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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TXN-IL1B (FusionGDB2 ID:HG7295TG3553)

Fusion Gene Summary for TXN-IL1B

check button Fusion gene summary
Fusion gene informationFusion gene name: TXN-IL1B
Fusion gene ID: hg7295tg3553
HgeneTgene
Gene symbol

TXN

IL1B

Gene ID

7295

3553

Gene namethioredoxininterleukin 1 beta
SynonymsTRDX|TRX|TRX1IL-1|IL1-BETA|IL1F2|IL1beta
Cytomap('TXN')('IL1B')

9q31.3

2q14.1

Type of geneprotein-codingprotein-coding
DescriptionthioredoxinADFATL-derived factorSASPTXN delta 3surface-associated sulphydryl proteintesticular tissue protein Li 199thioredoxin delta 3interleukin-1 betaIL-1 betacatabolininterleukin 1betapreinterleukin 1 betapro-interleukin-1-beta
Modification date2020032720200329
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000374515, ENST00000374517, 
ENST00000487892, 
Fusion gene scores* DoF score5 X 6 X 3=904 X 6 X 3=72
# samples 66
** MAII scorelog2(6/90*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/72*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TXN [Title/Abstract] AND IL1B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTXN(113007068)-IL1B(113587644), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTXN

GO:0009314

response to radiation

11118054

HgeneTXN

GO:0043388

positive regulation of DNA binding

11118054

HgeneTXN

GO:0055114

oxidation-reduction process

11118054

TgeneIL1B

GO:0000187

activation of MAPK activity

10748004

TgeneIL1B

GO:0001934

positive regulation of protein phosphorylation

10748004

TgeneIL1B

GO:0006954

inflammatory response

10748004|21147091

TgeneIL1B

GO:0008284

positive regulation of cell proliferation

25204733

TgeneIL1B

GO:0008285

negative regulation of cell proliferation

3493774

TgeneIL1B

GO:0010575

positive regulation of vascular endothelial growth factor production

12958148

TgeneIL1B

GO:0010628

positive regulation of gene expression

11090614|21559518|23817958|25327529|26687115|29384235

TgeneIL1B

GO:0010718

positive regulation of epithelial to mesenchymal transition

25204733

TgeneIL1B

GO:0019221

cytokine-mediated signaling pathway

10748004

TgeneIL1B

GO:0030213

hyaluronan biosynthetic process

15100360

TgeneIL1B

GO:0030335

positive regulation of cell migration

25204733

TgeneIL1B

GO:0030730

sequestering of triglyceride

19032770

TgeneIL1B

GO:0031663

lipopolysaccharide-mediated signaling pathway

21147091

TgeneIL1B

GO:0032496

response to lipopolysaccharide

19193853

TgeneIL1B

GO:0032725

positive regulation of granulocyte macrophage colony-stimulating factor production

20027291

TgeneIL1B

GO:0032729

positive regulation of interferon-gamma production

10653850|20027291

TgeneIL1B

GO:0032757

positive regulation of interleukin-8 production

19524870

TgeneIL1B

GO:0034116

positive regulation of heterotypic cell-cell adhesion

15100360

TgeneIL1B

GO:0035505

positive regulation of myosin light chain kinase activity

18390750

TgeneIL1B

GO:0035690

cellular response to drug

19158679

TgeneIL1B

GO:0042102

positive regulation of T cell proliferation

1919436

TgeneIL1B

GO:0043122

regulation of I-kappaB kinase/NF-kappaB signaling

10748004

TgeneIL1B

GO:0045429

positive regulation of nitric oxide biosynthetic process

8383325

TgeneIL1B

GO:0045766

positive regulation of angiogenesis

25204733

TgeneIL1B

GO:0045893

positive regulation of transcription, DNA-templated

15100360

TgeneIL1B

GO:0050796

regulation of insulin secretion

8383325

TgeneIL1B

GO:0050995

negative regulation of lipid catabolic process

19032770

TgeneIL1B

GO:0050999

regulation of nitric-oxide synthase activity

15899045

TgeneIL1B

GO:0051044

positive regulation of membrane protein ectodomain proteolysis

18373975

TgeneIL1B

GO:0051091

positive regulation of DNA-binding transcription factor activity

10748004

TgeneIL1B

GO:0051092

positive regulation of NF-kappaB transcription factor activity

10383454|12958148|25327529

TgeneIL1B

GO:0060559

positive regulation of calcidiol 1-monooxygenase activity

16720713|17023519

TgeneIL1B

GO:0070372

regulation of ERK1 and ERK2 cascade

25204733

TgeneIL1B

GO:0070487

monocyte aggregation

15100360

TgeneIL1B

GO:0070498

interleukin-1-mediated signaling pathway

25327529

TgeneIL1B

GO:0070555

response to interleukin-1

29441883

TgeneIL1B

GO:0071310

cellular response to organic substance

19158679

TgeneIL1B

GO:0071407

cellular response to organic cyclic compound

21147091

TgeneIL1B

GO:0071639

positive regulation of monocyte chemotactic protein-1 production

19524870

TgeneIL1B

GO:1901224

positive regulation of NIK/NF-kappaB signaling

18390750

TgeneIL1B

GO:1902680

positive regulation of RNA biosynthetic process

29384235

TgeneIL1B

GO:1903140

regulation of establishment of endothelial barrier

25816133

TgeneIL1B

GO:1903597

negative regulation of gap junction assembly

11090614

TgeneIL1B

GO:2000556

positive regulation of T-helper 1 cell cytokine production

10653850

TgeneIL1B

GO:2001240

negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

10748004



check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/AAA362147TXNchr9

113007068

-IL1Bchr2

113587644

-


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Fusion Gene ORF analysis for TXN-IL1B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3UTRENST00000374515ENST00000263341TXNchr9

113007068

-IL1Bchr2

113587644

-
intron-3UTRENST00000374517ENST00000263341TXNchr9

113007068

-IL1Bchr2

113587644

-
intron-3UTRENST00000487892ENST00000263341TXNchr9

113007068

-IL1Bchr2

113587644

-
intron-intronENST00000374515ENST00000491056TXNchr9

113007068

-IL1Bchr2

113587644

-
intron-intronENST00000374517ENST00000491056TXNchr9

113007068

-IL1Bchr2

113587644

-
intron-intronENST00000487892ENST00000491056TXNchr9

113007068

-IL1Bchr2

113587644

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for TXN-IL1B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)


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Fusion Protein Features for TXN-IL1B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:113007068/:113587644)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for TXN-IL1B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for TXN-IL1B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TXN-IL1B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TXN-IL1B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneTXNC0006142Malignant neoplasm of breast1CTD_human
HgeneTXNC0006287Bronchopulmonary Dysplasia1CTD_human
HgeneTXNC0011616Contact Dermatitis1CTD_human
HgeneTXNC0023895Liver diseases1CTD_human
HgeneTXNC0027626Neoplasm Invasiveness1CTD_human
HgeneTXNC0027627Neoplasm Metastasis1CTD_human
HgeneTXNC0027659Neoplasms, Experimental1CTD_human
HgeneTXNC0086565Liver Dysfunction1CTD_human
HgeneTXNC0162351Contact hypersensitivity1CTD_human
HgeneTXNC0242488Acute Lung Injury1CTD_human
HgeneTXNC0345967Malignant mesothelioma1CTD_human
HgeneTXNC0678222Breast Carcinoma1CTD_human
HgeneTXNC1257931Mammary Neoplasms, Human1CTD_human
HgeneTXNC1458155Mammary Neoplasms1CTD_human
HgeneTXNC4704874Mammary Carcinoma, Human1CTD_human
TgeneC0021368Inflammation9CTD_human
TgeneC0020429Hyperalgesia6CTD_human
TgeneC0458247Allodynia6CTD_human
TgeneC0751211Hyperalgesia, Primary6CTD_human
TgeneC0751212Hyperalgesia, Secondary6CTD_human
TgeneC0751213Tactile Allodynia6CTD_human
TgeneC0751214Hyperalgesia, Thermal6CTD_human
TgeneC2936719Mechanical Allodynia6CTD_human
TgeneC0005586Bipolar Disorder5PSYGENET
TgeneC0011570Mental Depression5PSYGENET
TgeneC0011581Depressive disorder5PSYGENET
TgeneC0015967Fever5CTD_human
TgeneC0035126Reperfusion Injury5CTD_human
TgeneC0041696Unipolar Depression5PSYGENET
TgeneC1269683Major Depressive Disorder5PSYGENET
TgeneC0001973Alcoholic Intoxication, Chronic4PSYGENET
TgeneC0003865Arthritis, Adjuvant-Induced4CTD_human
TgeneC0007786Brain Ischemia4CTD_human
TgeneC0009324Ulcerative Colitis4CTD_human
TgeneC0917798Cerebral Ischemia4CTD_human
TgeneC0971858Arthritis, Collagen-Induced4CTD_human
TgeneC0993582Arthritis, Experimental4CTD_human
TgeneC0003873Rheumatoid Arthritis3CTD_human
TgeneC0006142Malignant neoplasm of breast3CTD_human
TgeneC0007102Malignant tumor of colon3CTD_human
TgeneC0009375Colonic Neoplasms3CTD_human
TgeneC0020538Hypertensive disease3CTD_human
TgeneC0024623Malignant neoplasm of stomach3CTD_human
TgeneC0027051Myocardial Infarction3CTD_human
TgeneC0027540Necrosis3CTD_human
TgeneC0038356Stomach Neoplasms3CTD_human
TgeneC0678222Breast Carcinoma3CTD_human
TgeneC1257931Mammary Neoplasms, Human3CTD_human
TgeneC1458155Mammary Neoplasms3CTD_human
TgeneC1708349Hereditary Diffuse Gastric Cancer3CTD_human
TgeneC4704874Mammary Carcinoma, Human3CTD_human
TgeneC0009319Colitis2CTD_human
TgeneC0017658Glomerulonephritis2CTD_human
TgeneC0019193Hepatitis, Toxic2CTD_human
TgeneC0020649Hypotension2CTD_human
TgeneC0024121Lung Neoplasms2CTD_human
TgeneC0026769Multiple Sclerosis2CTD_human
TgeneC0034069Pulmonary Fibrosis2CTD_human
TgeneC0037274Dermatologic disorders2CTD_human
TgeneC0242379Malignant neoplasm of lung2CTD_human
TgeneC0751324Multiple Sclerosis, Acute Fulminating2CTD_human
TgeneC0860207Drug-Induced Liver Disease2CTD_human
TgeneC1262760Hepatitis, Drug-Induced2CTD_human
TgeneC1704377Bright Disease2CTD_human
TgeneC3658290Drug-Induced Acute Liver Injury2CTD_human
TgeneC4277682Chemical and Drug Induced Liver Injury2CTD_human
TgeneC4279912Chemically-Induced Liver Toxicity2CTD_human
TgeneC4721507Alveolitis, Fibrosing2CTD_human
TgeneC0000786Spontaneous abortion1CTD_human
TgeneC0000822Abortion, Tubal1CTD_human
TgeneC0001418Adenocarcinoma1CTD_human
TgeneC0002152Alloxan Diabetes1CTD_human
TgeneC0002395Alzheimer's Disease1CTD_human
TgeneC0003123Anorexia1CTD_human
TgeneC0003165Anthracosis1CTD_human
TgeneC0004096Asthma1CTD_human
TgeneC0005398Cholestasis, Extrahepatic1CTD_human
TgeneC0006287Bronchopulmonary Dysplasia1CTD_human
TgeneC0006663Calcinosis1CTD_human
TgeneC0006826Malignant Neoplasms1CTD_human
TgeneC0011265Presenile dementia1CTD_human
TgeneC0011615Dermatitis, Atopic1CTD_human
TgeneC0011633Dermatomyositis1CTD_human
TgeneC0011853Diabetes Mellitus, Experimental1CTD_human
TgeneC0014324Entamoebiasis1CTD_human
TgeneC0016059Fibrosis1CTD_human
TgeneC0017154Gastritis, Atrophic1CTD_human
TgeneC0017636Glioblastoma1CTD_human
TgeneC0018099Gout1CTD_human
TgeneC0018800Cardiomegaly1CTD_human
TgeneC0018801Heart failure1CTD_human
TgeneC0018802Congestive heart failure1CTD_human
TgeneC0018824Heart valve disease1CTD_human
TgeneC0019061Hemolytic-Uremic Syndrome1CTD_human
TgeneC0020452Hyperemia1CTD_human
TgeneC0020517Hypersensitivity1CTD_human
TgeneC0020615Hypoglycemia1CTD_human
TgeneC0022333Jacksonian Seizure1CTD_human
TgeneC0022541Kearns-Sayre syndrome1CTD_human
TgeneC0023186Learning Disorders1CTD_human
TgeneC0023212Left-Sided Heart Failure1CTD_human
TgeneC0023283Leishmaniasis, Cutaneous1CTD_human
TgeneC0023290Leishmaniasis, Visceral1CTD_human
TgeneC0023380Lethargy1CTD_human
TgeneC0023518Leukocytosis1CTD_human
TgeneC0023893Liver Cirrhosis, Experimental1CTD_human
TgeneC0024312Lymphopenia1CTD_human
TgeneC0024799Marginal ulcer1CTD_human
TgeneC0024809Marijuana Abuse1PSYGENET
TgeneC0025261Memory Disorders1CTD_human
TgeneC0026848Myopathy1CTD_human
TgeneC0027626Neoplasm Invasiveness1CTD_human
TgeneC0027651Neoplasms1CTD_human
TgeneC0027947Neutropenia1CTD_human
TgeneC0029408Degenerative polyarthritis1CTD_human
TgeneC0029458Osteoporosis, Postmenopausal1CTD_human
TgeneC0030246Pustulosis of Palms and Soles1CTD_human
TgeneC0030920Peptic Ulcer1CTD_human
TgeneC0032231Pleurisy1CTD_human
TgeneC0032285Pneumonia1CTD_human
TgeneC0032300Lobar Pneumonia1CTD_human
TgeneC0033141Cardiomyopathies, Primary1CTD_human
TgeneC0033860Psoriasis1CTD_human
TgeneC0036341Schizophrenia1CTD_human
TgeneC0036529Myocardial Diseases, Secondary1CTD_human
TgeneC0036572Seizures1CTD_human
TgeneC0037116Silicosis1CTD_human
TgeneC0038358Gastric ulcer1CTD_human
TgeneC0038433Streptozotocin Diabetes1CTD_human
TgeneC0038454Cerebrovascular accident1CTD_human
TgeneC0040136Thyroid Neoplasm1CTD_human
TgeneC0040997Trigeminal Neuralgia1CTD_human
TgeneC0042109Urticaria1CTD_human
TgeneC0042484Venous Engorgement1CTD_human
TgeneC0085655Polymyositis1CTD_human
TgeneC0086196Eczema, Infantile1CTD_human
TgeneC0086540Leishmaniasis, New World1CTD_human
TgeneC0086541Urban cutaneous leishmaniasis1CTD_human
TgeneC0086692Benign Neoplasm1CTD_human
TgeneC0086743Osteoarthrosis Deformans1CTD_human
TgeneC0149958Complex partial seizures1CTD_human
TgeneC0151468Thyroid Gland Follicular Adenoma1CTD_human
TgeneC0151744Myocardial Ischemia1CTD_human
TgeneC0151857Pleocytosis1CTD_human
TgeneC0162668Megaconial Myopathies1CTD_human
TgeneC0162669Pleoconial Myopathies1CTD_human
TgeneC0162670Mitochondrial Myopathies1CTD_human
TgeneC0162671MELAS Syndrome1CTD_human
TgeneC0162672MERRF Syndrome1CTD_human
TgeneC0162674Chronic progressive external ophthalmoplegia1CTD_human
TgeneC0178824Reactive Hyperemia1CTD_human
TgeneC0205641Adenocarcinoma, Basal Cell1CTD_human
TgeneC0205642Adenocarcinoma, Oxyphilic1CTD_human
TgeneC0205643Carcinoma, Cribriform1CTD_human
TgeneC0205644Carcinoma, Granular Cell1CTD_human
TgeneC0205645Adenocarcinoma, Tubular1CTD_human
TgeneC0221056Adult type dermatomyositis1CTD_human
TgeneC0233794Memory impairment1CTD_human
TgeneC0234533Generalized seizures1CTD_human
TgeneC0234535Clonic Seizures1CTD_human
TgeneC0235527Heart Failure, Right-Sided1CTD_human
TgeneC0238281Middle Cerebral Artery Syndrome1CTD_human
TgeneC0263628Tumoral calcinosis1CTD_human
TgeneC0263666Dermatomyositis, Childhood Type1CTD_human
TgeneC0263984Polymyositis Ossificans1CTD_human
TgeneC0270824Visual seizure1CTD_human
TgeneC0270844Tonic Seizures1CTD_human
TgeneC0270846Epileptic drop attack1CTD_human
TgeneC0271708Fasting Hypoglycemia1CTD_human
TgeneC0271710Reactive hypoglycemia1CTD_human
TgeneC0274861Arsenic Poisoning, Inorganic1CTD_human
TgeneC0274862Nervous System, Organic Arsenic Poisoning1CTD_human
TgeneC0276496Familial Alzheimer Disease (FAD)1CTD_human
TgeneC0311375Arsenic Poisoning1CTD_human
TgeneC0333233Active Hyperemia1CTD_human
TgeneC0333355Inflammatory disease of mucous membrane1CTD_human
TgeneC0334588Giant Cell Glioblastoma1CTD_human
TgeneC0343755HIV Wasting Syndrome1CTD_human
TgeneC0393786Trigeminal Neuralgia, Idiopathic1CTD_human
TgeneC0393787Secondary Trigeminal Neuralgia1CTD_human
TgeneC0422850Seizures, Somatosensory1CTD_human
TgeneC0422852Seizures, Auditory1CTD_human
TgeneC0422853Olfactory seizure1CTD_human
TgeneC0422854Gustatory seizure1CTD_human
TgeneC0422855Vertiginous seizure1CTD_human
TgeneC0494463Alzheimer Disease, Late Onset1CTD_human
TgeneC0494475Tonic - clonic seizures1CTD_human
TgeneC0521174Microcalcification1CTD_human
TgeneC0546126Acute Confusional Senile Dementia1CTD_human
TgeneC0549473Thyroid carcinoma1CTD_human
TgeneC0554591Polymyositis, Idiopathic1CTD_human
TgeneC0677050Manganese Poisoning1CTD_human
TgeneC0740376Middle Cerebral Artery Thrombosis1CTD_human
TgeneC0740391Middle Cerebral Artery Occlusion1CTD_human
TgeneC0740392Infarction, Middle Cerebral Artery1CTD_human
TgeneC0750900Alzheimer's Disease, Focal Onset1CTD_human
TgeneC0750901Alzheimer Disease, Early Onset1CTD_human
TgeneC0751056Non-epileptic convulsion1CTD_human
TgeneC0751110Single Seizure1CTD_human
TgeneC0751123Atonic Absence Seizures1CTD_human
TgeneC0751262Adult Learning Disorders1CTD_human
TgeneC0751263Learning Disturbance1CTD_human
TgeneC0751265Learning Disabilities1CTD_human
TgeneC0751292Age-Related Memory Disorders1CTD_human
TgeneC0751293Memory Disorder, Semantic1CTD_human
TgeneC0751294Memory Disorder, Spatial1CTD_human
TgeneC0751295Memory Loss1CTD_human
TgeneC0751494Convulsive Seizures1CTD_human
TgeneC0751495Seizures, Focal1CTD_human
TgeneC0751496Seizures, Sensory1CTD_human
TgeneC0751508Long Sleeper Syndrome1CTD_human
TgeneC0751509Short Sleeper Syndrome1CTD_human
TgeneC0751510Sleep-Related Neurogenic Tachypnea1CTD_human
TgeneC0751511Subwakefullness Syndrome1CTD_human
TgeneC0751845Middle Cerebral Artery Embolus1CTD_human
TgeneC0751846Left Middle Cerebral Artery Infarction1CTD_human
TgeneC0751847Embolic Infarction, Middle Cerebral Artery1CTD_human
TgeneC0751848Thrombotic Infarction, Middle Cerebral Artery1CTD_human
TgeneC0751849Right Middle Cerebral Artery Infarction1CTD_human
TgeneC0751851Arsenic Encephalopathy1CTD_human
TgeneC0751852Arsenic Induced Polyneuropathy1CTD_human
TgeneC0751956Acute Cerebrovascular Accidents1CTD_human
TgeneC0851578Sleep Disorders1CTD_human
TgeneC0878544Cardiomyopathies1CTD_human
TgeneC0887898Experimental Lung Inflammation1CTD_human
TgeneC0917796Optic Atrophy, Hereditary, Leber1CTD_human
TgeneC0949496Luft Disease1CTD_human
TgeneC1330966Developmental Academic Disorder1CTD_human
TgeneC1383860Cardiac Hypertrophy1CTD_human
TgeneC1527304Allergic Reaction1CTD_human
TgeneC1621958Glioblastoma Multiforme1CTD_human
TgeneC1623038Cirrhosis1CTD_human
TgeneC1858361Pyogenic Arthritis, Pyoderma Gangrenosum and Acne1CTD_human
TgeneC1959583Myocardial Failure1CTD_human
TgeneC1961112Heart Decompensation1CTD_human
TgeneC3495874Nonepileptic Seizures1CTD_human
TgeneC3714636Pneumonitis1CTD_human
TgeneC3830362Early Pregnancy Loss1CTD_human
TgeneC4042891Sleep Wake Disorders1CTD_human
TgeneC4048158Convulsions1CTD_human
TgeneC4316791Entamoeba histolytica Infection1CTD_human
TgeneC4316903Absence Seizures1CTD_human
TgeneC4317109Epileptic Seizures1CTD_human
TgeneC4317123Myoclonic Seizures1CTD_human
TgeneC4505436Generalized Absence Seizures1CTD_human
TgeneC4552766Miscarriage1CTD_human