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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:UQCRC2-SRSF7 (FusionGDB2 ID:HG7385TG6432) |
Fusion Gene Summary for UQCRC2-SRSF7 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: UQCRC2-SRSF7 | Fusion gene ID: hg7385tg6432 | Hgene | Tgene | Gene symbol | UQCRC2 | SRSF7 | Gene ID | 7385 | 6432 |
| Gene name | ubiquinol-cytochrome c reductase core protein 2 | serine and arginine rich splicing factor 7 | |
| Synonyms | MC3DN5|QCR2|UQCR2 | 9G8|AAG3|SFRS7 | |
| Cytomap | ('UQCRC2')('SRSF7') 16p12.2 | 2p22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cytochrome b-c1 complex subunit 2, mitochondrialcomplex III subunit 2cytochrome bc-1 complex core protein IIubiquinol-cytochrome c reductase core protein IIubiquinol-cytochrome-c reductase complex core protein 2 | serine/arginine-rich splicing factor 7SR splicing factor 7aging-associated protein 3splicing factor 9G8splicing factor, arginine/serine-rich 7, 35kDa | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000268379, ENST00000561553, | ||
| Fusion gene scores | * DoF score | 12 X 8 X 6=576 | 10 X 5 X 7=350 |
| # samples | 13 | 10 | |
| ** MAII score | log2(13/576*10)=-2.14755718841386 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(10/350*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: UQCRC2 [Title/Abstract] AND SRSF7 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | UQCRC2(21987564)-SRSF7(38973889), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | UQCRC2-SRSF7 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. UQCRC2-SRSF7 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | SRSF7 | GO:0008380 | RNA splicing | 8013463 |
| Tgene | SRSF7 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome | 15009664 |
| Fusion gene breakpoints across UQCRC2 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across SRSF7 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | Non-Cancer | 269N | UQCRC2 | chr16 | 21987564 | + | SRSF7 | chr2 | 38973889 | - |
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Fusion Gene ORF analysis for UQCRC2-SRSF7 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000268379 | ENST00000313117 | UQCRC2 | chr16 | 21987564 | + | SRSF7 | chr2 | 38973889 | - |
| In-frame | ENST00000268379 | ENST00000409276 | UQCRC2 | chr16 | 21987564 | + | SRSF7 | chr2 | 38973889 | - |
| In-frame | ENST00000268379 | ENST00000446327 | UQCRC2 | chr16 | 21987564 | + | SRSF7 | chr2 | 38973889 | - |
| In-frame | ENST00000561553 | ENST00000313117 | UQCRC2 | chr16 | 21987564 | + | SRSF7 | chr2 | 38973889 | - |
| In-frame | ENST00000561553 | ENST00000409276 | UQCRC2 | chr16 | 21987564 | + | SRSF7 | chr2 | 38973889 | - |
| In-frame | ENST00000561553 | ENST00000446327 | UQCRC2 | chr16 | 21987564 | + | SRSF7 | chr2 | 38973889 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000268379 | UQCRC2 | chr16 | 21987564 | + | ENST00000313117 | SRSF7 | chr2 | 38973889 | - | 3567 | 1888 | 764 | 2032 | 422 |
| ENST00000268379 | UQCRC2 | chr16 | 21987564 | + | ENST00000446327 | SRSF7 | chr2 | 38973889 | - | 2380 | 1888 | 764 | 1996 | 410 |
| ENST00000268379 | UQCRC2 | chr16 | 21987564 | + | ENST00000409276 | SRSF7 | chr2 | 38973889 | - | 2273 | 1888 | 764 | 2032 | 422 |
| ENST00000561553 | UQCRC2 | chr16 | 21987564 | + | ENST00000313117 | SRSF7 | chr2 | 38973889 | - | 2856 | 1177 | 53 | 1321 | 422 |
| ENST00000561553 | UQCRC2 | chr16 | 21987564 | + | ENST00000446327 | SRSF7 | chr2 | 38973889 | - | 1669 | 1177 | 53 | 1285 | 410 |
| ENST00000561553 | UQCRC2 | chr16 | 21987564 | + | ENST00000409276 | SRSF7 | chr2 | 38973889 | - | 1562 | 1177 | 53 | 1321 | 422 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000268379 | ENST00000313117 | UQCRC2 | chr16 | 21987564 | + | SRSF7 | chr2 | 38973889 | - | 0.001583181 | 0.9984168 |
| ENST00000268379 | ENST00000446327 | UQCRC2 | chr16 | 21987564 | + | SRSF7 | chr2 | 38973889 | - | 0.002148126 | 0.99785185 |
| ENST00000268379 | ENST00000409276 | UQCRC2 | chr16 | 21987564 | + | SRSF7 | chr2 | 38973889 | - | 0.00364077 | 0.99635917 |
| ENST00000561553 | ENST00000313117 | UQCRC2 | chr16 | 21987564 | + | SRSF7 | chr2 | 38973889 | - | 0.001476331 | 0.99852365 |
| ENST00000561553 | ENST00000446327 | UQCRC2 | chr16 | 21987564 | + | SRSF7 | chr2 | 38973889 | - | 0.001823185 | 0.9981768 |
| ENST00000561553 | ENST00000409276 | UQCRC2 | chr16 | 21987564 | + | SRSF7 | chr2 | 38973889 | - | 0.003249888 | 0.9967501 |
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Fusion Genomic Features for UQCRC2-SRSF7 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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Fusion Protein Features for UQCRC2-SRSF7 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:21987564/chr2:38973889) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000313117 | 4 | 8 | 211_218 | 190 | 239.0 | Repeat | Note=5%3B approximate | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000313117 | 4 | 8 | 219_226 | 190 | 239.0 | Repeat | Note=6%3B approximate | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000446327 | 4 | 7 | 211_218 | 190 | 227.0 | Repeat | Note=5%3B approximate | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000446327 | 4 | 7 | 219_226 | 190 | 227.0 | Repeat | Note=6%3B approximate |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000313117 | 4 | 8 | 121_238 | 190 | 239.0 | Compositional bias | Note=Arg/Ser-rich (RS domain) | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000446327 | 4 | 7 | 121_238 | 190 | 227.0 | Compositional bias | Note=Arg/Ser-rich (RS domain) | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000313117 | 4 | 8 | 11_84 | 190 | 239.0 | Domain | RRM | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000446327 | 4 | 7 | 11_84 | 190 | 227.0 | Domain | RRM | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000313117 | 4 | 8 | 153_226 | 190 | 239.0 | Region | Note=6 X 8 AA repeats of R-R-S-R-S-X-S-X | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000446327 | 4 | 7 | 153_226 | 190 | 227.0 | Region | Note=6 X 8 AA repeats of R-R-S-R-S-X-S-X | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000313117 | 4 | 8 | 153_160 | 190 | 239.0 | Repeat | Note=1 | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000313117 | 4 | 8 | 161_168 | 190 | 239.0 | Repeat | Note=2 | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000313117 | 4 | 8 | 169_176 | 190 | 239.0 | Repeat | Note=3 | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000313117 | 4 | 8 | 177_184 | 190 | 239.0 | Repeat | Note=4 | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000446327 | 4 | 7 | 153_160 | 190 | 227.0 | Repeat | Note=1 | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000446327 | 4 | 7 | 161_168 | 190 | 227.0 | Repeat | Note=2 | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000446327 | 4 | 7 | 169_176 | 190 | 227.0 | Repeat | Note=3 | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000446327 | 4 | 7 | 177_184 | 190 | 227.0 | Repeat | Note=4 | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000313117 | 4 | 8 | 104_120 | 190 | 239.0 | Zinc finger | CCHC-type | |
| Tgene | SRSF7 | chr16:21987564 | chr2:38973889 | ENST00000446327 | 4 | 7 | 104_120 | 190 | 227.0 | Zinc finger | CCHC-type |
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Fusion Gene Sequence for UQCRC2-SRSF7 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >97015_97015_1_UQCRC2-SRSF7_UQCRC2_chr16_21987564_ENST00000268379_SRSF7_chr2_38973889_ENST00000313117_length(transcript)=3567nt_BP=1888nt ACTATCCAAAACATTTCTATTTTCCTAACACAAAAACTATAGCTAAGTTTTTATATTCTATGTAGCCCCAGCCTAGGACGTAAATTCCAC GAGACCAAAAGCCTTGTGATGATTCCCCGAGGTTGCTGACCCTCCCGGTGTGTCCCGGGCCTGCTCTGGGGGACACAGCGGCGAATACGT TGAACGAGGCCCCTGTTTCACGGAGCTAAAGATCCAGTAAGGACTTCACCCAGCGAGAGGCAACTACGCCGGGCTTCGATACCCAATACC TCTGCAGAAAGGTGGAGTGGCAGGAATCTCCTGAAGCCTCCAACGTCCAGGAACGCGGAAACCCAGGGCCTCCAGTGCAGGTGTCATCCC GGAGGGCGCATGCGGAGTCCCAAGAGAGGCGCGTCCCATTGGACAATGCTGAGCGGAAGAGCCCAAGATAGCGGGGGGAGTTGTGACAGG CTGCTGCAGACGTACTTAGAAAAGGGGTGCATACTGGATATTCAGGCTAGGAGAAGAACGCAAAAAGCAGTGACGTACATTATTCTCTGC ATATATTTACTTGGGAAATTGTGCGTCTCCCTATTCTGAGTCTTGGAGGAATTGGACTGGTCCAACCTTATAAAGAGAGCAGTAGAGCGC GGCAGTATAGAGAGTACCTCACGAAGGGGACGTGGGAAAGTGTTAGCGGGGAACGCTGGGAAACTCCCGGCCTCCGCCACCATCTTGCTT TCCTTTAATCCGGCAGTGACCGTGTGTCAGAACAATCTTGAATCATGAAGCTACTAACCAGAGCCGGCTCTTTCTCGAGATTTTATTCCC TCAAAGTTGCCCCCAAAGTTAAAGCCACAGCTGCGCCTGCAGGAGCACCGCCACAACCTCAGGACCTTGAGTTTACCAAGTTACCAAATG GCTTGGTGATTGCTTCTTTGGAAAACTATTCTCCTGTATCAAGAATTGGTTTGTTCATTAAAGCAGGCAGTAGATATGAGGACTTCAGCA ATTTAGGAACCACCCATTTGCTGCGTCTTACATCCAGTCTGACGACAAAAGGAGCTTCATCTTTCAAGATAACCCGTGGAATTGAAGCAG TTGGTGGCAAATTAAGTGTGACCGCAACAAGGGAAAACATGGCTTATACTGTGGAATGCCTGCGGGGTGATGTTGATATTCTAATGGAGT TCCTGCTCAATGTCACCACAGCACCAGAATTTCGTCGTTGGGAAGTAGCTGACCTTCAGCCTCAGCTAAAGATTGACAAAGCTGTGGCCT TTCAGAATCCGCAGACTCATGTCATTGAAAATTTGCATGCAGCAGCTTACCGGAATGCCTTGGCTAATCCCTTGTATTGTCCTGACTATA GGATTGGAAAAGTGACATCAGAGGAGTTACATTACTTCGTTCAGAACCATTTCACAAGTGCAAGAATGGCTTTGATTGGACTTGGTGTGA GTCATCCTGTTCTAAAGCAAGTTGCTGAACAGTTTCTCAACATGAGGGGTGGGCTTGGTTTATCTGGTGCAAAGGCCAACTACCGTGGAG GTGAAATCCGAGAACAGAATGGAGACAGTCTTGTCCATGCTGCTTTTGTAGCAGAAAGTGCTGTCGCGGGAAGTGCAGAGGCAAATGCAT TTAGTGTTCTTCAGCATGTCCTCGGTGCTGGGCCACATGTCAAGAGGGGCAGCAACACCACCAGCCATCTGCACCAGGCTGTTGCCAAGG CAACTCAGCAGCCATTTGATGTTTCTGCATTTAATGCCAGTTACTCAGATTCTGGACTCTTTGGGATTTATACTATCTCCCAGGCCACAG CTGCTGGAGATGTTATCAAGGCTGCCTATAATCAAGTAAAAACAATAGCTCAAGGAAACCTTTCCAACACAGATGTCCAAGCTGCCAAAT CCCCGTCGAGGTCAAGATCAAGATCCAGGTCTATTTCACGACCAAGAAGCAGCCGATCAAAGTCCAGATCTCCATCTCCAAAAAGAAGTC GTTCCCCATCAGGAAGTCCTCGCAGAAGTGCAAGTCCTGAAAGAATGGACTGAAGCTCTCAAGTTCACCCTTTAGGGAAAAGTTATTTTG TTTACATTATTATAAGGGATTTGTGATGTCTGTAAAGTGTAACCTAGGAAAGATAATTCAACCATCTAATCAAAATGGATCTGGATTACT ATGTAAATTCACAGCAGTAAGATAATATAAATTTTGTTGAATGTATTAACATCATATGGTCTGAAAATGTGGGTTTTTATTTGGCACATT TAAATAAAATGTTTCTAACTAGATTTTTGATTTGTGTTCAATATTAACACTTCTTAATTTGATATATTTGAGAGTCAGACATTATAATTG TTAACCTTATTCATACATACCTACATTCAGAATTGAAAGGTGTTGGTTAAGTCTTGAACATCACTATTCTATGCATAAAACTTGGCCAGG ATCTTAAGGGACTTTGAAAATTCCATCTTACCCTTGTAGCTCTGGGTAAGATGACCTGAGTCCCTTATGATACAGCCTGAATGCATCATG ACAGATCCTTAAGTTAGCTAATCCGTTTGAAGTTGGTGTTAGTAGGTATTGTATGATCAGTGGTGAAGCAAGTAGGACCACTGATGTGTC TAAATGAGCATGACAGGAACTAAACGAAACTGATTAAATGTATGAGAAATAGAAACATTTCTGGATGATCTTTATACTAATTGCAGCTTT CAGGCTACTAGGTGGCATAGTGTTAATTAGGACTCCCCAAGATATGGGGAGTTCTACTCTCAATGGTCTTGTTTCTTTGCTTTCTACATT AGTTAACCAGTTTTATACCAAAAAATGCATGTTTGAGGAATTGTCTGAAATTGGGACAAAACACCTTCATGTAAACCAGCTTTGCAAAAT TTTCCAGCCCAGATACTCTTCATCTATTCAAATGGATTGTCTTATTCTGAGCAAAGACCTGTTGTTAATCTTCAAGCTAGGTTTTGCAGT TCCCAACCACAACATTCTTCTATTTTGCCAGGCTGGTGCAAAGTAATTAAAGATGTCAATCAGAAATGTCAATGAGACTAAAGTGGTTTT GTAAATCTCAGCTATATTTAGCAACACTCCATGTAGCTAATATTTTTTGGTAGCATCTGGTAGACCTTAGAATGTTACATAGCCAGTAGG TTCTTTATTCAAATTTTAAGTATCTTAAGAATAGTAGGGCAGTAACAGTTACTTTTGAGAGTTTTCTGGTCAAGCTTTTACCAGGCATTC TCTAGCCTTGGTACAAAAAAAAAAAAACCTGCTGGTTGCGCAGATACCTAGGCTTGTCCATTTTATGCATTTCAGCAAAGTCATTGGATA CTATTGCAACTTGGGAATACTGGTCTGCATCAAGTTTATTCGGTAGTTTGACCGCTAGTATGTTGGAAGTTATTTGGATTGTTTTTGGAA TTTTGACTGGCTGAATTATGGTTGGTATAAAGTTATGTGTATAACTGGCAGGCTTATTTATCTGTTGCACTTGGTTAGCTTTAATTGTTC >97015_97015_1_UQCRC2-SRSF7_UQCRC2_chr16_21987564_ENST00000268379_SRSF7_chr2_38973889_ENST00000313117_length(amino acids)=422AA_BP=375 MKLLTRAGSFSRFYSLKVAPKVKATAAPAGAPPQPQDLEFTKLPNGLVIASLENYSPVSRIGLFIKAGSRYEDFSNLGTTHLLRLTSSLT TKGASSFKITRGIEAVGGKLSVTATRENMAYTVECLRGDVDILMEFLLNVTTAPEFRRWEVADLQPQLKIDKAVAFQNPQTHVIENLHAA AYRNALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGVSHPVLKQVAEQFLNMRGGLGLSGAKANYRGGEIREQNGDSLVHAA FVAESAVAGSAEANAFSVLQHVLGAGPHVKRGSNTTSHLHQAVAKATQQPFDVSAFNASYSDSGLFGIYTISQATAAGDVIKAAYNQVKT -------------------------------------------------------------- >97015_97015_2_UQCRC2-SRSF7_UQCRC2_chr16_21987564_ENST00000268379_SRSF7_chr2_38973889_ENST00000409276_length(transcript)=2273nt_BP=1888nt ACTATCCAAAACATTTCTATTTTCCTAACACAAAAACTATAGCTAAGTTTTTATATTCTATGTAGCCCCAGCCTAGGACGTAAATTCCAC GAGACCAAAAGCCTTGTGATGATTCCCCGAGGTTGCTGACCCTCCCGGTGTGTCCCGGGCCTGCTCTGGGGGACACAGCGGCGAATACGT TGAACGAGGCCCCTGTTTCACGGAGCTAAAGATCCAGTAAGGACTTCACCCAGCGAGAGGCAACTACGCCGGGCTTCGATACCCAATACC TCTGCAGAAAGGTGGAGTGGCAGGAATCTCCTGAAGCCTCCAACGTCCAGGAACGCGGAAACCCAGGGCCTCCAGTGCAGGTGTCATCCC GGAGGGCGCATGCGGAGTCCCAAGAGAGGCGCGTCCCATTGGACAATGCTGAGCGGAAGAGCCCAAGATAGCGGGGGGAGTTGTGACAGG CTGCTGCAGACGTACTTAGAAAAGGGGTGCATACTGGATATTCAGGCTAGGAGAAGAACGCAAAAAGCAGTGACGTACATTATTCTCTGC ATATATTTACTTGGGAAATTGTGCGTCTCCCTATTCTGAGTCTTGGAGGAATTGGACTGGTCCAACCTTATAAAGAGAGCAGTAGAGCGC GGCAGTATAGAGAGTACCTCACGAAGGGGACGTGGGAAAGTGTTAGCGGGGAACGCTGGGAAACTCCCGGCCTCCGCCACCATCTTGCTT TCCTTTAATCCGGCAGTGACCGTGTGTCAGAACAATCTTGAATCATGAAGCTACTAACCAGAGCCGGCTCTTTCTCGAGATTTTATTCCC TCAAAGTTGCCCCCAAAGTTAAAGCCACAGCTGCGCCTGCAGGAGCACCGCCACAACCTCAGGACCTTGAGTTTACCAAGTTACCAAATG GCTTGGTGATTGCTTCTTTGGAAAACTATTCTCCTGTATCAAGAATTGGTTTGTTCATTAAAGCAGGCAGTAGATATGAGGACTTCAGCA ATTTAGGAACCACCCATTTGCTGCGTCTTACATCCAGTCTGACGACAAAAGGAGCTTCATCTTTCAAGATAACCCGTGGAATTGAAGCAG TTGGTGGCAAATTAAGTGTGACCGCAACAAGGGAAAACATGGCTTATACTGTGGAATGCCTGCGGGGTGATGTTGATATTCTAATGGAGT TCCTGCTCAATGTCACCACAGCACCAGAATTTCGTCGTTGGGAAGTAGCTGACCTTCAGCCTCAGCTAAAGATTGACAAAGCTGTGGCCT TTCAGAATCCGCAGACTCATGTCATTGAAAATTTGCATGCAGCAGCTTACCGGAATGCCTTGGCTAATCCCTTGTATTGTCCTGACTATA GGATTGGAAAAGTGACATCAGAGGAGTTACATTACTTCGTTCAGAACCATTTCACAAGTGCAAGAATGGCTTTGATTGGACTTGGTGTGA GTCATCCTGTTCTAAAGCAAGTTGCTGAACAGTTTCTCAACATGAGGGGTGGGCTTGGTTTATCTGGTGCAAAGGCCAACTACCGTGGAG GTGAAATCCGAGAACAGAATGGAGACAGTCTTGTCCATGCTGCTTTTGTAGCAGAAAGTGCTGTCGCGGGAAGTGCAGAGGCAAATGCAT TTAGTGTTCTTCAGCATGTCCTCGGTGCTGGGCCACATGTCAAGAGGGGCAGCAACACCACCAGCCATCTGCACCAGGCTGTTGCCAAGG CAACTCAGCAGCCATTTGATGTTTCTGCATTTAATGCCAGTTACTCAGATTCTGGACTCTTTGGGATTTATACTATCTCCCAGGCCACAG CTGCTGGAGATGTTATCAAGGCTGCCTATAATCAAGTAAAAACAATAGCTCAAGGAAACCTTTCCAACACAGATGTCCAAGCTGCCAAAT CCCCGTCGAGGTCAAGATCAAGATCCAGGTCTATTTCACGACCAAGAAGCAGCCGATCAAAGTCCAGATCTCCATCTCCAAAAAGAAGTC GTTCCCCATCAGGAAGTCCTCGCAGAAGTGCAAGTCCTGAAAGAATGGACTGAAGCTCTCAAGTTCACCCTTTAGGGAAAAGTTATTTTG TTTACATTATTATAAGGGATTTGTGATGTCTGTAAAGTGTAACCTAGGAAAGATAATTCAACCATCTAATCAAAATGGATCTGGATTACT ATGTAAATTCACAGCAGTAAGATAATATAAATTTTGTTGAATGTATTAACATCATATGGTCTGAAAATGTGGGTTTTTATTTGGCACATT >97015_97015_2_UQCRC2-SRSF7_UQCRC2_chr16_21987564_ENST00000268379_SRSF7_chr2_38973889_ENST00000409276_length(amino acids)=422AA_BP=375 MKLLTRAGSFSRFYSLKVAPKVKATAAPAGAPPQPQDLEFTKLPNGLVIASLENYSPVSRIGLFIKAGSRYEDFSNLGTTHLLRLTSSLT TKGASSFKITRGIEAVGGKLSVTATRENMAYTVECLRGDVDILMEFLLNVTTAPEFRRWEVADLQPQLKIDKAVAFQNPQTHVIENLHAA AYRNALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGVSHPVLKQVAEQFLNMRGGLGLSGAKANYRGGEIREQNGDSLVHAA FVAESAVAGSAEANAFSVLQHVLGAGPHVKRGSNTTSHLHQAVAKATQQPFDVSAFNASYSDSGLFGIYTISQATAAGDVIKAAYNQVKT -------------------------------------------------------------- >97015_97015_3_UQCRC2-SRSF7_UQCRC2_chr16_21987564_ENST00000268379_SRSF7_chr2_38973889_ENST00000446327_length(transcript)=2380nt_BP=1888nt ACTATCCAAAACATTTCTATTTTCCTAACACAAAAACTATAGCTAAGTTTTTATATTCTATGTAGCCCCAGCCTAGGACGTAAATTCCAC GAGACCAAAAGCCTTGTGATGATTCCCCGAGGTTGCTGACCCTCCCGGTGTGTCCCGGGCCTGCTCTGGGGGACACAGCGGCGAATACGT TGAACGAGGCCCCTGTTTCACGGAGCTAAAGATCCAGTAAGGACTTCACCCAGCGAGAGGCAACTACGCCGGGCTTCGATACCCAATACC TCTGCAGAAAGGTGGAGTGGCAGGAATCTCCTGAAGCCTCCAACGTCCAGGAACGCGGAAACCCAGGGCCTCCAGTGCAGGTGTCATCCC GGAGGGCGCATGCGGAGTCCCAAGAGAGGCGCGTCCCATTGGACAATGCTGAGCGGAAGAGCCCAAGATAGCGGGGGGAGTTGTGACAGG CTGCTGCAGACGTACTTAGAAAAGGGGTGCATACTGGATATTCAGGCTAGGAGAAGAACGCAAAAAGCAGTGACGTACATTATTCTCTGC ATATATTTACTTGGGAAATTGTGCGTCTCCCTATTCTGAGTCTTGGAGGAATTGGACTGGTCCAACCTTATAAAGAGAGCAGTAGAGCGC GGCAGTATAGAGAGTACCTCACGAAGGGGACGTGGGAAAGTGTTAGCGGGGAACGCTGGGAAACTCCCGGCCTCCGCCACCATCTTGCTT TCCTTTAATCCGGCAGTGACCGTGTGTCAGAACAATCTTGAATCATGAAGCTACTAACCAGAGCCGGCTCTTTCTCGAGATTTTATTCCC TCAAAGTTGCCCCCAAAGTTAAAGCCACAGCTGCGCCTGCAGGAGCACCGCCACAACCTCAGGACCTTGAGTTTACCAAGTTACCAAATG GCTTGGTGATTGCTTCTTTGGAAAACTATTCTCCTGTATCAAGAATTGGTTTGTTCATTAAAGCAGGCAGTAGATATGAGGACTTCAGCA ATTTAGGAACCACCCATTTGCTGCGTCTTACATCCAGTCTGACGACAAAAGGAGCTTCATCTTTCAAGATAACCCGTGGAATTGAAGCAG TTGGTGGCAAATTAAGTGTGACCGCAACAAGGGAAAACATGGCTTATACTGTGGAATGCCTGCGGGGTGATGTTGATATTCTAATGGAGT TCCTGCTCAATGTCACCACAGCACCAGAATTTCGTCGTTGGGAAGTAGCTGACCTTCAGCCTCAGCTAAAGATTGACAAAGCTGTGGCCT TTCAGAATCCGCAGACTCATGTCATTGAAAATTTGCATGCAGCAGCTTACCGGAATGCCTTGGCTAATCCCTTGTATTGTCCTGACTATA GGATTGGAAAAGTGACATCAGAGGAGTTACATTACTTCGTTCAGAACCATTTCACAAGTGCAAGAATGGCTTTGATTGGACTTGGTGTGA GTCATCCTGTTCTAAAGCAAGTTGCTGAACAGTTTCTCAACATGAGGGGTGGGCTTGGTTTATCTGGTGCAAAGGCCAACTACCGTGGAG GTGAAATCCGAGAACAGAATGGAGACAGTCTTGTCCATGCTGCTTTTGTAGCAGAAAGTGCTGTCGCGGGAAGTGCAGAGGCAAATGCAT TTAGTGTTCTTCAGCATGTCCTCGGTGCTGGGCCACATGTCAAGAGGGGCAGCAACACCACCAGCCATCTGCACCAGGCTGTTGCCAAGG CAACTCAGCAGCCATTTGATGTTTCTGCATTTAATGCCAGTTACTCAGATTCTGGACTCTTTGGGATTTATACTATCTCCCAGGCCACAG CTGCTGGAGATGTTATCAAGGCTGCCTATAATCAAGTAAAAACAATAGCTCAAGGAAACCTTTCCAACACAGATGTCCAAGCTGCCAAAT CCCCGTCGAGGTCAAGATCAAGATCCAGGTCTATTTCACGACCAAGAAGCAGTCGTTCCCCATCAGGAAGTCCTCGCAGAAGTGCAAGTC CTGAAAGAATGGACTGAAGCTCTCAAGTTCACCCTTTAGGGAAAAGTTATTTTGTTTACATTATTATAAGGGATTTGTGATGTCTGTAAA GTGTAACCTAGGAAAGATAATTCAACCATCTAATCAAAATGGATCTGGATTACTATGTAAATTCACAGCAGTAAGATAATATAAATTTTG TTGAATGTATTAACATCATATGGTCTGAAAATGTGGGTTTTTATTTGGCACATTTAAATAAAATGTTTCTAACTAGATTTTTGATTTGTG TTCAATATTAACACTTCTTAATTTGATATATTTGAGAGTCAGACATTATAATTGTTAACCTTATTCATACATACCTACATTCAGAATTGA >97015_97015_3_UQCRC2-SRSF7_UQCRC2_chr16_21987564_ENST00000268379_SRSF7_chr2_38973889_ENST00000446327_length(amino acids)=410AA_BP=375 MKLLTRAGSFSRFYSLKVAPKVKATAAPAGAPPQPQDLEFTKLPNGLVIASLENYSPVSRIGLFIKAGSRYEDFSNLGTTHLLRLTSSLT TKGASSFKITRGIEAVGGKLSVTATRENMAYTVECLRGDVDILMEFLLNVTTAPEFRRWEVADLQPQLKIDKAVAFQNPQTHVIENLHAA AYRNALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGVSHPVLKQVAEQFLNMRGGLGLSGAKANYRGGEIREQNGDSLVHAA FVAESAVAGSAEANAFSVLQHVLGAGPHVKRGSNTTSHLHQAVAKATQQPFDVSAFNASYSDSGLFGIYTISQATAAGDVIKAAYNQVKT -------------------------------------------------------------- >97015_97015_4_UQCRC2-SRSF7_UQCRC2_chr16_21987564_ENST00000561553_SRSF7_chr2_38973889_ENST00000313117_length(transcript)=2856nt_BP=1177nt ATCTTGCTTTCCTTTAATCCGGCAGTGACCGTGTGTCAGAACAATCTTGAATCATGAAGCTACTAACCAGAGCCGGCTCTTTCTCGAGAT TTTATTCCCTCAAAGTTGCCCCCAAAGTTAAAGCCACAGCTGCGCCTGCAGGAGCACCGCCACAACCTCAGGACCTTGAGTTTACCAAGT TACCAAATGGCTTGGTGATTGCTTCTTTGGAAAACTATTCTCCTGTATCAAGAATTGGTTTGTTCATTAAAGCAGGCAGTAGATATGAGG ACTTCAGCAATTTAGGAACCACCCATTTGCTGCGTCTTACATCCAGTCTGACGACAAAAGGAGCTTCATCTTTCAAGATAACCCGTGGAA TTGAAGCAGTTGGTGGCAAATTAAGTGTGACCGCAACAAGGGAAAACATGGCTTATACTGTGGAATGCCTGCGGGGTGATGTTGATATTC TAATGGAGTTCCTGCTCAATGTCACCACAGCACCAGAATTTCGTCGTTGGGAAGTAGCTGACCTTCAGCCTCAGCTAAAGATTGACAAAG CTGTGGCCTTTCAGAATCCGCAGACTCATGTCATTGAAAATTTGCATGCAGCAGCTTACCGGAATGCCTTGGCTAATCCCTTGTATTGTC CTGACTATAGGATTGGAAAAGTGACATCAGAGGAGTTACATTACTTCGTTCAGAACCATTTCACAAGTGCAAGAATGGCTTTGATTGGAC TTGGTGTGAGTCATCCTGTTCTAAAGCAAGTTGCTGAACAGTTTCTCAACATGAGGGGTGGGCTTGGTTTATCTGGTGCAAAGGCCAACT ACCGTGGAGGTGAAATCCGAGAACAGAATGGAGACAGTCTTGTCCATGCTGCTTTTGTAGCAGAAAGTGCTGTCGCGGGAAGTGCAGAGG CAAATGCATTTAGTGTTCTTCAGCATGTCCTCGGTGCTGGGCCACATGTCAAGAGGGGCAGCAACACCACCAGCCATCTGCACCAGGCTG TTGCCAAGGCAACTCAGCAGCCATTTGATGTTTCTGCATTTAATGCCAGTTACTCAGATTCTGGACTCTTTGGGATTTATACTATCTCCC AGGCCACAGCTGCTGGAGATGTTATCAAGGCTGCCTATAATCAAGTAAAAACAATAGCTCAAGGAAACCTTTCCAACACAGATGTCCAAG CTGCCAAATCCCCGTCGAGGTCAAGATCAAGATCCAGGTCTATTTCACGACCAAGAAGCAGCCGATCAAAGTCCAGATCTCCATCTCCAA AAAGAAGTCGTTCCCCATCAGGAAGTCCTCGCAGAAGTGCAAGTCCTGAAAGAATGGACTGAAGCTCTCAAGTTCACCCTTTAGGGAAAA GTTATTTTGTTTACATTATTATAAGGGATTTGTGATGTCTGTAAAGTGTAACCTAGGAAAGATAATTCAACCATCTAATCAAAATGGATC TGGATTACTATGTAAATTCACAGCAGTAAGATAATATAAATTTTGTTGAATGTATTAACATCATATGGTCTGAAAATGTGGGTTTTTATT TGGCACATTTAAATAAAATGTTTCTAACTAGATTTTTGATTTGTGTTCAATATTAACACTTCTTAATTTGATATATTTGAGAGTCAGACA TTATAATTGTTAACCTTATTCATACATACCTACATTCAGAATTGAAAGGTGTTGGTTAAGTCTTGAACATCACTATTCTATGCATAAAAC TTGGCCAGGATCTTAAGGGACTTTGAAAATTCCATCTTACCCTTGTAGCTCTGGGTAAGATGACCTGAGTCCCTTATGATACAGCCTGAA TGCATCATGACAGATCCTTAAGTTAGCTAATCCGTTTGAAGTTGGTGTTAGTAGGTATTGTATGATCAGTGGTGAAGCAAGTAGGACCAC TGATGTGTCTAAATGAGCATGACAGGAACTAAACGAAACTGATTAAATGTATGAGAAATAGAAACATTTCTGGATGATCTTTATACTAAT TGCAGCTTTCAGGCTACTAGGTGGCATAGTGTTAATTAGGACTCCCCAAGATATGGGGAGTTCTACTCTCAATGGTCTTGTTTCTTTGCT TTCTACATTAGTTAACCAGTTTTATACCAAAAAATGCATGTTTGAGGAATTGTCTGAAATTGGGACAAAACACCTTCATGTAAACCAGCT TTGCAAAATTTTCCAGCCCAGATACTCTTCATCTATTCAAATGGATTGTCTTATTCTGAGCAAAGACCTGTTGTTAATCTTCAAGCTAGG TTTTGCAGTTCCCAACCACAACATTCTTCTATTTTGCCAGGCTGGTGCAAAGTAATTAAAGATGTCAATCAGAAATGTCAATGAGACTAA AGTGGTTTTGTAAATCTCAGCTATATTTAGCAACACTCCATGTAGCTAATATTTTTTGGTAGCATCTGGTAGACCTTAGAATGTTACATA GCCAGTAGGTTCTTTATTCAAATTTTAAGTATCTTAAGAATAGTAGGGCAGTAACAGTTACTTTTGAGAGTTTTCTGGTCAAGCTTTTAC CAGGCATTCTCTAGCCTTGGTACAAAAAAAAAAAAACCTGCTGGTTGCGCAGATACCTAGGCTTGTCCATTTTATGCATTTCAGCAAAGT CATTGGATACTATTGCAACTTGGGAATACTGGTCTGCATCAAGTTTATTCGGTAGTTTGACCGCTAGTATGTTGGAAGTTATTTGGATTG TTTTTGGAATTTTGACTGGCTGAATTATGGTTGGTATAAAGTTATGTGTATAACTGGCAGGCTTATTTATCTGTTGCACTTGGTTAGCTT >97015_97015_4_UQCRC2-SRSF7_UQCRC2_chr16_21987564_ENST00000561553_SRSF7_chr2_38973889_ENST00000313117_length(amino acids)=422AA_BP=375 MKLLTRAGSFSRFYSLKVAPKVKATAAPAGAPPQPQDLEFTKLPNGLVIASLENYSPVSRIGLFIKAGSRYEDFSNLGTTHLLRLTSSLT TKGASSFKITRGIEAVGGKLSVTATRENMAYTVECLRGDVDILMEFLLNVTTAPEFRRWEVADLQPQLKIDKAVAFQNPQTHVIENLHAA AYRNALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGVSHPVLKQVAEQFLNMRGGLGLSGAKANYRGGEIREQNGDSLVHAA FVAESAVAGSAEANAFSVLQHVLGAGPHVKRGSNTTSHLHQAVAKATQQPFDVSAFNASYSDSGLFGIYTISQATAAGDVIKAAYNQVKT -------------------------------------------------------------- >97015_97015_5_UQCRC2-SRSF7_UQCRC2_chr16_21987564_ENST00000561553_SRSF7_chr2_38973889_ENST00000409276_length(transcript)=1562nt_BP=1177nt ATCTTGCTTTCCTTTAATCCGGCAGTGACCGTGTGTCAGAACAATCTTGAATCATGAAGCTACTAACCAGAGCCGGCTCTTTCTCGAGAT TTTATTCCCTCAAAGTTGCCCCCAAAGTTAAAGCCACAGCTGCGCCTGCAGGAGCACCGCCACAACCTCAGGACCTTGAGTTTACCAAGT TACCAAATGGCTTGGTGATTGCTTCTTTGGAAAACTATTCTCCTGTATCAAGAATTGGTTTGTTCATTAAAGCAGGCAGTAGATATGAGG ACTTCAGCAATTTAGGAACCACCCATTTGCTGCGTCTTACATCCAGTCTGACGACAAAAGGAGCTTCATCTTTCAAGATAACCCGTGGAA TTGAAGCAGTTGGTGGCAAATTAAGTGTGACCGCAACAAGGGAAAACATGGCTTATACTGTGGAATGCCTGCGGGGTGATGTTGATATTC TAATGGAGTTCCTGCTCAATGTCACCACAGCACCAGAATTTCGTCGTTGGGAAGTAGCTGACCTTCAGCCTCAGCTAAAGATTGACAAAG CTGTGGCCTTTCAGAATCCGCAGACTCATGTCATTGAAAATTTGCATGCAGCAGCTTACCGGAATGCCTTGGCTAATCCCTTGTATTGTC CTGACTATAGGATTGGAAAAGTGACATCAGAGGAGTTACATTACTTCGTTCAGAACCATTTCACAAGTGCAAGAATGGCTTTGATTGGAC TTGGTGTGAGTCATCCTGTTCTAAAGCAAGTTGCTGAACAGTTTCTCAACATGAGGGGTGGGCTTGGTTTATCTGGTGCAAAGGCCAACT ACCGTGGAGGTGAAATCCGAGAACAGAATGGAGACAGTCTTGTCCATGCTGCTTTTGTAGCAGAAAGTGCTGTCGCGGGAAGTGCAGAGG CAAATGCATTTAGTGTTCTTCAGCATGTCCTCGGTGCTGGGCCACATGTCAAGAGGGGCAGCAACACCACCAGCCATCTGCACCAGGCTG TTGCCAAGGCAACTCAGCAGCCATTTGATGTTTCTGCATTTAATGCCAGTTACTCAGATTCTGGACTCTTTGGGATTTATACTATCTCCC AGGCCACAGCTGCTGGAGATGTTATCAAGGCTGCCTATAATCAAGTAAAAACAATAGCTCAAGGAAACCTTTCCAACACAGATGTCCAAG CTGCCAAATCCCCGTCGAGGTCAAGATCAAGATCCAGGTCTATTTCACGACCAAGAAGCAGCCGATCAAAGTCCAGATCTCCATCTCCAA AAAGAAGTCGTTCCCCATCAGGAAGTCCTCGCAGAAGTGCAAGTCCTGAAAGAATGGACTGAAGCTCTCAAGTTCACCCTTTAGGGAAAA GTTATTTTGTTTACATTATTATAAGGGATTTGTGATGTCTGTAAAGTGTAACCTAGGAAAGATAATTCAACCATCTAATCAAAATGGATC TGGATTACTATGTAAATTCACAGCAGTAAGATAATATAAATTTTGTTGAATGTATTAACATCATATGGTCTGAAAATGTGGGTTTTTATT >97015_97015_5_UQCRC2-SRSF7_UQCRC2_chr16_21987564_ENST00000561553_SRSF7_chr2_38973889_ENST00000409276_length(amino acids)=422AA_BP=375 MKLLTRAGSFSRFYSLKVAPKVKATAAPAGAPPQPQDLEFTKLPNGLVIASLENYSPVSRIGLFIKAGSRYEDFSNLGTTHLLRLTSSLT TKGASSFKITRGIEAVGGKLSVTATRENMAYTVECLRGDVDILMEFLLNVTTAPEFRRWEVADLQPQLKIDKAVAFQNPQTHVIENLHAA AYRNALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGVSHPVLKQVAEQFLNMRGGLGLSGAKANYRGGEIREQNGDSLVHAA FVAESAVAGSAEANAFSVLQHVLGAGPHVKRGSNTTSHLHQAVAKATQQPFDVSAFNASYSDSGLFGIYTISQATAAGDVIKAAYNQVKT -------------------------------------------------------------- >97015_97015_6_UQCRC2-SRSF7_UQCRC2_chr16_21987564_ENST00000561553_SRSF7_chr2_38973889_ENST00000446327_length(transcript)=1669nt_BP=1177nt ATCTTGCTTTCCTTTAATCCGGCAGTGACCGTGTGTCAGAACAATCTTGAATCATGAAGCTACTAACCAGAGCCGGCTCTTTCTCGAGAT TTTATTCCCTCAAAGTTGCCCCCAAAGTTAAAGCCACAGCTGCGCCTGCAGGAGCACCGCCACAACCTCAGGACCTTGAGTTTACCAAGT TACCAAATGGCTTGGTGATTGCTTCTTTGGAAAACTATTCTCCTGTATCAAGAATTGGTTTGTTCATTAAAGCAGGCAGTAGATATGAGG ACTTCAGCAATTTAGGAACCACCCATTTGCTGCGTCTTACATCCAGTCTGACGACAAAAGGAGCTTCATCTTTCAAGATAACCCGTGGAA TTGAAGCAGTTGGTGGCAAATTAAGTGTGACCGCAACAAGGGAAAACATGGCTTATACTGTGGAATGCCTGCGGGGTGATGTTGATATTC TAATGGAGTTCCTGCTCAATGTCACCACAGCACCAGAATTTCGTCGTTGGGAAGTAGCTGACCTTCAGCCTCAGCTAAAGATTGACAAAG CTGTGGCCTTTCAGAATCCGCAGACTCATGTCATTGAAAATTTGCATGCAGCAGCTTACCGGAATGCCTTGGCTAATCCCTTGTATTGTC CTGACTATAGGATTGGAAAAGTGACATCAGAGGAGTTACATTACTTCGTTCAGAACCATTTCACAAGTGCAAGAATGGCTTTGATTGGAC TTGGTGTGAGTCATCCTGTTCTAAAGCAAGTTGCTGAACAGTTTCTCAACATGAGGGGTGGGCTTGGTTTATCTGGTGCAAAGGCCAACT ACCGTGGAGGTGAAATCCGAGAACAGAATGGAGACAGTCTTGTCCATGCTGCTTTTGTAGCAGAAAGTGCTGTCGCGGGAAGTGCAGAGG CAAATGCATTTAGTGTTCTTCAGCATGTCCTCGGTGCTGGGCCACATGTCAAGAGGGGCAGCAACACCACCAGCCATCTGCACCAGGCTG TTGCCAAGGCAACTCAGCAGCCATTTGATGTTTCTGCATTTAATGCCAGTTACTCAGATTCTGGACTCTTTGGGATTTATACTATCTCCC AGGCCACAGCTGCTGGAGATGTTATCAAGGCTGCCTATAATCAAGTAAAAACAATAGCTCAAGGAAACCTTTCCAACACAGATGTCCAAG CTGCCAAATCCCCGTCGAGGTCAAGATCAAGATCCAGGTCTATTTCACGACCAAGAAGCAGTCGTTCCCCATCAGGAAGTCCTCGCAGAA GTGCAAGTCCTGAAAGAATGGACTGAAGCTCTCAAGTTCACCCTTTAGGGAAAAGTTATTTTGTTTACATTATTATAAGGGATTTGTGAT GTCTGTAAAGTGTAACCTAGGAAAGATAATTCAACCATCTAATCAAAATGGATCTGGATTACTATGTAAATTCACAGCAGTAAGATAATA TAAATTTTGTTGAATGTATTAACATCATATGGTCTGAAAATGTGGGTTTTTATTTGGCACATTTAAATAAAATGTTTCTAACTAGATTTT TGATTTGTGTTCAATATTAACACTTCTTAATTTGATATATTTGAGAGTCAGACATTATAATTGTTAACCTTATTCATACATACCTACATT >97015_97015_6_UQCRC2-SRSF7_UQCRC2_chr16_21987564_ENST00000561553_SRSF7_chr2_38973889_ENST00000446327_length(amino acids)=410AA_BP=375 MKLLTRAGSFSRFYSLKVAPKVKATAAPAGAPPQPQDLEFTKLPNGLVIASLENYSPVSRIGLFIKAGSRYEDFSNLGTTHLLRLTSSLT TKGASSFKITRGIEAVGGKLSVTATRENMAYTVECLRGDVDILMEFLLNVTTAPEFRRWEVADLQPQLKIDKAVAFQNPQTHVIENLHAA AYRNALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGVSHPVLKQVAEQFLNMRGGLGLSGAKANYRGGEIREQNGDSLVHAA FVAESAVAGSAEANAFSVLQHVLGAGPHVKRGSNTTSHLHQAVAKATQQPFDVSAFNASYSDSGLFGIYTISQATAAGDVIKAAYNQVKT -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for UQCRC2-SRSF7 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for UQCRC2-SRSF7 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for UQCRC2-SRSF7 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | UQCRC2 | C0028754 | Obesity | 1 | CTD_human |
| Hgene | UQCRC2 | C3554608 | MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 5 | 1 | GENOMICS_ENGLAND;UNIPROT |
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