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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:HM13-BCL2L1 (FusionGDB2 ID:HG81502TG598)

Fusion Gene Summary for HM13-BCL2L1

check button Fusion gene summary
Fusion gene informationFusion gene name: HM13-BCL2L1
Fusion gene ID: hg81502tg598
HgeneTgene
Gene symbol

HM13

BCL2L1

Gene ID

81502

598

Gene namehistocompatibility minor 13BCL2 like 1
SynonymsH13|IMP1|IMPAS|IMPAS-1|MSTP086|PSENL3|PSL3|SPP|SPPL1BCL-XL/S|BCL2L|BCLX|Bcl-X|PPP1R52
Cytomap('HM13')('BCL2L1')

20q11.21

20q11.21

Type of geneprotein-codingprotein-coding
Descriptionminor histocompatibility antigen H13intramembrane protease 1minor histocompatibility antigen 13presenilin-like protein 3signal peptide peptidase betasignal peptide peptidase like 1bcl-2-like protein 1apoptosis regulator Bcl-Xprotein phosphatase 1, regulatory subunit 52
Modification date2020031320200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000492709, ENST00000335574, 
ENST00000340852, ENST00000376127, 
ENST00000398174, 
Fusion gene scores* DoF score12 X 11 X 7=92410 X 5 X 10=500
# samples 1311
** MAII scorelog2(13/924*10)=-2.8293812283876
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/500*10)=-2.18442457113743
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: HM13 [Title/Abstract] AND BCL2L1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointHM13(30126064)-BCL2L1(30253889), # samples:2
Anticipated loss of major functional domain due to fusion event.HM13-BCL2L1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
HM13-BCL2L1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
HM13-BCL2L1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
HM13-BCL2L1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
HM13-BCL2L1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
HM13-BCL2L1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneHM13

GO:0033619

membrane protein proteolysis

14741365

TgeneBCL2L1

GO:0001836

release of cytochrome c from mitochondria

9843949

TgeneBCL2L1

GO:0019050

suppression by virus of host apoptotic process

15231831

TgeneBCL2L1

GO:0034097

response to cytokine

9184696

TgeneBCL2L1

GO:0043066

negative regulation of apoptotic process

7650367|9388232

TgeneBCL2L1

GO:0046902

regulation of mitochondrial membrane permeability

9843949

TgeneBCL2L1

GO:0051881

regulation of mitochondrial membrane potential

9843949

TgeneBCL2L1

GO:1900118

negative regulation of execution phase of apoptosis

20673843

TgeneBCL2L1

GO:1902042

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

26582200

TgeneBCL2L1

GO:1902230

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

16608847

TgeneBCL2L1

GO:1902236

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

29507230

TgeneBCL2L1

GO:1903077

negative regulation of protein localization to plasma membrane

21041309

TgeneBCL2L1

GO:2001243

negative regulation of intrinsic apoptotic signaling pathway

12011449


check buttonFusion gene breakpoints across HM13 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across BCL2L1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-GC-A3I6-01AHM13chr20

30115385

+BCL2L1chr20

30253889

-
ChimerDB4BLCATCGA-GC-A3I6-01AHM13chr20

30126064

+BCL2L1chr20

30253889

-
ChimerDB4BLCATCGA-GC-A3I6HM13chr20

30126064

+BCL2L1chr20

30253889

-


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Fusion Gene ORF analysis for HM13-BCL2L1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000492709ENST00000307677HM13chr20

30126064

+BCL2L1chr20

30253889

-
3UTR-3CDSENST00000492709ENST00000376055HM13chr20

30126064

+BCL2L1chr20

30253889

-
3UTR-3CDSENST00000492709ENST00000376062HM13chr20

30126064

+BCL2L1chr20

30253889

-
3UTR-3CDSENST00000492709ENST00000420653HM13chr20

30126064

+BCL2L1chr20

30253889

-
Frame-shiftENST00000335574ENST00000307677HM13chr20

30115385

+BCL2L1chr20

30253889

-
Frame-shiftENST00000335574ENST00000376055HM13chr20

30115385

+BCL2L1chr20

30253889

-
Frame-shiftENST00000335574ENST00000376055HM13chr20

30126064

+BCL2L1chr20

30253889

-
Frame-shiftENST00000335574ENST00000376062HM13chr20

30126064

+BCL2L1chr20

30253889

-
Frame-shiftENST00000335574ENST00000420653HM13chr20

30115385

+BCL2L1chr20

30253889

-
Frame-shiftENST00000335574ENST00000420653HM13chr20

30126064

+BCL2L1chr20

30253889

-
Frame-shiftENST00000340852ENST00000307677HM13chr20

30115385

+BCL2L1chr20

30253889

-
Frame-shiftENST00000340852ENST00000376055HM13chr20

30115385

+BCL2L1chr20

30253889

-
Frame-shiftENST00000340852ENST00000376055HM13chr20

30126064

+BCL2L1chr20

30253889

-
Frame-shiftENST00000340852ENST00000376062HM13chr20

30126064

+BCL2L1chr20

30253889

-
Frame-shiftENST00000340852ENST00000420653HM13chr20

30115385

+BCL2L1chr20

30253889

-
Frame-shiftENST00000340852ENST00000420653HM13chr20

30126064

+BCL2L1chr20

30253889

-
Frame-shiftENST00000376127ENST00000307677HM13chr20

30115385

+BCL2L1chr20

30253889

-
Frame-shiftENST00000376127ENST00000376055HM13chr20

30115385

+BCL2L1chr20

30253889

-
Frame-shiftENST00000376127ENST00000376055HM13chr20

30126064

+BCL2L1chr20

30253889

-
Frame-shiftENST00000376127ENST00000376062HM13chr20

30126064

+BCL2L1chr20

30253889

-
Frame-shiftENST00000376127ENST00000420653HM13chr20

30115385

+BCL2L1chr20

30253889

-
Frame-shiftENST00000376127ENST00000420653HM13chr20

30126064

+BCL2L1chr20

30253889

-
Frame-shiftENST00000398174ENST00000307677HM13chr20

30115385

+BCL2L1chr20

30253889

-
Frame-shiftENST00000398174ENST00000376055HM13chr20

30115385

+BCL2L1chr20

30253889

-
Frame-shiftENST00000398174ENST00000376055HM13chr20

30126064

+BCL2L1chr20

30253889

-
Frame-shiftENST00000398174ENST00000376062HM13chr20

30126064

+BCL2L1chr20

30253889

-
Frame-shiftENST00000398174ENST00000420653HM13chr20

30115385

+BCL2L1chr20

30253889

-
Frame-shiftENST00000398174ENST00000420653HM13chr20

30126064

+BCL2L1chr20

30253889

-
In-frameENST00000335574ENST00000307677HM13chr20

30126064

+BCL2L1chr20

30253889

-
In-frameENST00000335574ENST00000376062HM13chr20

30115385

+BCL2L1chr20

30253889

-
In-frameENST00000340852ENST00000307677HM13chr20

30126064

+BCL2L1chr20

30253889

-
In-frameENST00000340852ENST00000376062HM13chr20

30115385

+BCL2L1chr20

30253889

-
In-frameENST00000376127ENST00000307677HM13chr20

30126064

+BCL2L1chr20

30253889

-
In-frameENST00000376127ENST00000376062HM13chr20

30115385

+BCL2L1chr20

30253889

-
In-frameENST00000398174ENST00000307677HM13chr20

30126064

+BCL2L1chr20

30253889

-
In-frameENST00000398174ENST00000376062HM13chr20

30115385

+BCL2L1chr20

30253889

-
intron-3CDSENST00000492709ENST00000307677HM13chr20

30115385

+BCL2L1chr20

30253889

-
intron-3CDSENST00000492709ENST00000376055HM13chr20

30115385

+BCL2L1chr20

30253889

-
intron-3CDSENST00000492709ENST00000376062HM13chr20

30115385

+BCL2L1chr20

30253889

-
intron-3CDSENST00000492709ENST00000420653HM13chr20

30115385

+BCL2L1chr20

30253889

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000398174HM13chr2030126064+ENST00000307677BCL2L1chr2030253889-212448947637196
ENST00000340852HM13chr2030126064+ENST00000307677BCL2L1chr2030253889-212448947637196
ENST00000335574HM13chr2030126064+ENST00000307677BCL2L1chr2030253889-212448947637196
ENST00000376127HM13chr2030126064+ENST00000307677BCL2L1chr2030253889-209345816606196
ENST00000398174HM13chr2030115385+ENST00000376062BCL2L1chr2030253889-204140612851869194
ENST00000340852HM13chr2030115385+ENST00000376062BCL2L1chr2030253889-204140612851869194
ENST00000335574HM13chr2030115385+ENST00000376062BCL2L1chr2030253889-204140612851869194
ENST00000376127HM13chr2030115385+ENST00000376062BCL2L1chr2030253889-201037512541838194

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000398174ENST00000307677HM13chr2030126064+BCL2L1chr2030253889-0.41507670.58492327
ENST00000340852ENST00000307677HM13chr2030126064+BCL2L1chr2030253889-0.41507670.58492327
ENST00000335574ENST00000307677HM13chr2030126064+BCL2L1chr2030253889-0.41507670.58492327
ENST00000376127ENST00000307677HM13chr2030126064+BCL2L1chr2030253889-0.360830040.63916993
ENST00000398174ENST00000376062HM13chr2030115385+BCL2L1chr2030253889-0.43325880.56674117
ENST00000340852ENST00000376062HM13chr2030115385+BCL2L1chr2030253889-0.43325880.56674117
ENST00000335574ENST00000376062HM13chr2030115385+BCL2L1chr2030253889-0.43325880.56674117
ENST00000376127ENST00000376062HM13chr2030115385+BCL2L1chr2030253889-0.363059730.6369403

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Fusion Genomic Features for HM13-BCL2L1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for HM13-BCL2L1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:30126064/chr20:30253889)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+2131_3194442.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+21353_7794442.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+2121_3194378.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+21253_7794378.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+2111_3194336.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+21153_7794336.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+2131_3194427.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+21353_7794427.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+3131_31121442.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+31353_77121442.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+31399_100121442.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+3121_31121378.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+31253_77121378.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+31299_100121378.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+3111_31121336.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+31153_77121336.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+31199_100121336.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+3131_31121427.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+31353_77121427.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+31399_100121427.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+21332_5294442.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+21232_5294378.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+21132_5294336.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+21332_5294427.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+313101_121121442.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+31332_52121442.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+31378_98121442.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+312101_121121378.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+31232_52121378.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+31278_98121378.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+311101_121121336.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+31132_52121336.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+31178_98121336.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+313101_121121427.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+31332_52121427.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+31378_98121427.0TransmembraneHelical
TgeneBCL2L1chr20:30115385chr20:30253889ENST0000037605513129_148125171.0MotifNote=BH1
TgeneBCL2L1chr20:30115385chr20:30253889ENST0000037605513180_195125171.0MotifNote=BH2
TgeneBCL2L1chr20:30126064chr20:30253889ENST0000037605513129_148125171.0MotifNote=BH1
TgeneBCL2L1chr20:30126064chr20:30253889ENST0000037605513180_195125171.0MotifNote=BH2
TgeneBCL2L1chr20:30115385chr20:30253889ENST0000030767713210_226188234.0TransmembraneHelical
TgeneBCL2L1chr20:30115385chr20:30253889ENST0000037605513210_226125171.0TransmembraneHelical
TgeneBCL2L1chr20:30115385chr20:30253889ENST0000037606202210_226188234.0TransmembraneHelical
TgeneBCL2L1chr20:30115385chr20:30253889ENST0000042065313210_226188234.0TransmembraneHelical
TgeneBCL2L1chr20:30126064chr20:30253889ENST0000030767713210_226188234.0TransmembraneHelical
TgeneBCL2L1chr20:30126064chr20:30253889ENST0000037605513210_226125171.0TransmembraneHelical
TgeneBCL2L1chr20:30126064chr20:30253889ENST0000037606202210_226188234.0TransmembraneHelical
TgeneBCL2L1chr20:30126064chr20:30253889ENST0000042065313210_226188234.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+213317_31994442.0MotifNote=PAL
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+212317_31994378.0MotifNote=PAL
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+211317_31994336.0MotifNote=PAL
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+213317_31994427.0MotifNote=PAL
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+313317_319121442.0MotifNote=PAL
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+312317_319121378.0MotifNote=PAL
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+311317_319121336.0MotifNote=PAL
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+313317_319121427.0MotifNote=PAL
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+213122_15794442.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+213179_18194442.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+213203_20994442.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+213231_25694442.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+213278_29094442.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+213312_31494442.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+213336_37794442.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+21399_10094442.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+212122_15794378.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+212179_18194378.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+212203_20994378.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+212231_25694378.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+212278_29094378.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+212312_31494378.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+212336_37794378.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+21299_10094378.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+211122_15794336.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+211179_18194336.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+211203_20994336.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+211231_25694336.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+211278_29094336.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+211312_31494336.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+211336_37794336.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+21199_10094336.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+213122_15794427.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+213179_18194427.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+213203_20994427.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+213231_25694427.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+213278_29094427.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+213312_31494427.0Topological domainLumenal
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+213336_37794427.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+21399_10094427.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+313122_157121442.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+313179_181121442.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+313203_209121442.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+313231_256121442.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+313278_290121442.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+313312_314121442.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+313336_377121442.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+312122_157121378.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+312179_181121378.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+312203_209121378.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+312231_256121378.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+312278_290121378.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+312312_314121378.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+312336_377121378.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+311122_157121336.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+311179_181121336.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+311203_209121336.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+311231_256121336.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+311278_290121336.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+311312_314121336.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+311336_377121336.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+313122_157121427.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+313179_181121427.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+313203_209121427.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+313231_256121427.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+313278_290121427.0Topological domainCytoplasmic
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+313312_314121427.0Topological domainLumenal
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+313336_377121427.0Topological domainCytoplasmic
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+213101_12194442.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+213158_17894442.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+213182_20294442.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+213210_23094442.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+213257_27794442.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+213291_31194442.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+213315_33594442.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000335574+21378_9894442.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+212101_12194378.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+212158_17894378.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+212182_20294378.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+212210_23094378.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+212257_27794378.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+212291_31194378.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+212315_33594378.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000340852+21278_9894378.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+211101_12194336.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+211158_17894336.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+211182_20294336.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+211210_23094336.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+211257_27794336.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+211291_31194336.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+211315_33594336.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000376127+21178_9894336.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+213101_12194427.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+213158_17894427.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+213182_20294427.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+213210_23094427.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+213257_27794427.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+213291_31194427.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+213315_33594427.0TransmembraneHelical
HgeneHM13chr20:30115385chr20:30253889ENST00000398174+21378_9894427.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+313158_178121442.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+313182_202121442.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+313210_230121442.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+313257_277121442.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+313291_311121442.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000335574+313315_335121442.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+312158_178121378.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+312182_202121378.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+312210_230121378.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+312257_277121378.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+312291_311121378.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000340852+312315_335121378.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+311158_178121336.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+311182_202121336.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+311210_230121336.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+311257_277121336.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+311291_311121336.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000376127+311315_335121336.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+313158_178121427.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+313182_202121427.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+313210_230121427.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+313257_277121427.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+313291_311121427.0TransmembraneHelical
HgeneHM13chr20:30126064chr20:30253889ENST00000398174+313315_335121427.0TransmembraneHelical
TgeneBCL2L1chr20:30115385chr20:30253889ENST0000030767713129_148188234.0MotifNote=BH1
TgeneBCL2L1chr20:30115385chr20:30253889ENST0000030767713180_195188234.0MotifNote=BH2
TgeneBCL2L1chr20:30115385chr20:30253889ENST00000307677134_24188234.0MotifNote=BH4
TgeneBCL2L1chr20:30115385chr20:30253889ENST000003076771386_100188234.0MotifNote=BH3
TgeneBCL2L1chr20:30115385chr20:30253889ENST00000376055134_24125171.0MotifNote=BH4
TgeneBCL2L1chr20:30115385chr20:30253889ENST000003760551386_100125171.0MotifNote=BH3
TgeneBCL2L1chr20:30115385chr20:30253889ENST0000037606202129_148188234.0MotifNote=BH1
TgeneBCL2L1chr20:30115385chr20:30253889ENST0000037606202180_195188234.0MotifNote=BH2
TgeneBCL2L1chr20:30115385chr20:30253889ENST00000376062024_24188234.0MotifNote=BH4
TgeneBCL2L1chr20:30115385chr20:30253889ENST000003760620286_100188234.0MotifNote=BH3
TgeneBCL2L1chr20:30115385chr20:30253889ENST0000042065313129_148188234.0MotifNote=BH1
TgeneBCL2L1chr20:30115385chr20:30253889ENST0000042065313180_195188234.0MotifNote=BH2
TgeneBCL2L1chr20:30115385chr20:30253889ENST00000420653134_24188234.0MotifNote=BH4
TgeneBCL2L1chr20:30115385chr20:30253889ENST000004206531386_100188234.0MotifNote=BH3
TgeneBCL2L1chr20:30126064chr20:30253889ENST0000030767713129_148188234.0MotifNote=BH1
TgeneBCL2L1chr20:30126064chr20:30253889ENST0000030767713180_195188234.0MotifNote=BH2
TgeneBCL2L1chr20:30126064chr20:30253889ENST00000307677134_24188234.0MotifNote=BH4
TgeneBCL2L1chr20:30126064chr20:30253889ENST000003076771386_100188234.0MotifNote=BH3
TgeneBCL2L1chr20:30126064chr20:30253889ENST00000376055134_24125171.0MotifNote=BH4
TgeneBCL2L1chr20:30126064chr20:30253889ENST000003760551386_100125171.0MotifNote=BH3
TgeneBCL2L1chr20:30126064chr20:30253889ENST0000037606202129_148188234.0MotifNote=BH1
TgeneBCL2L1chr20:30126064chr20:30253889ENST0000037606202180_195188234.0MotifNote=BH2
TgeneBCL2L1chr20:30126064chr20:30253889ENST00000376062024_24188234.0MotifNote=BH4
TgeneBCL2L1chr20:30126064chr20:30253889ENST000003760620286_100188234.0MotifNote=BH3
TgeneBCL2L1chr20:30126064chr20:30253889ENST0000042065313129_148188234.0MotifNote=BH1
TgeneBCL2L1chr20:30126064chr20:30253889ENST0000042065313180_195188234.0MotifNote=BH2
TgeneBCL2L1chr20:30126064chr20:30253889ENST00000420653134_24188234.0MotifNote=BH4
TgeneBCL2L1chr20:30126064chr20:30253889ENST000004206531386_100188234.0MotifNote=BH3


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Fusion Gene Sequence for HM13-BCL2L1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>36744_36744_1_HM13-BCL2L1_HM13_chr20_30115385_ENST00000335574_BCL2L1_chr20_30253889_ENST00000376062_length(transcript)=2041nt_BP=406nt
GGAGGGAGCACGTCACTTCCTGTTGCCTTAGGGGAACGTGGCTTTCCCTGCAGAGCCGGTGTCTCCGCCTGCGTCCCTGCTGCAGCAACC
GGAGCTGGAGTCGGATCCCGAACGCACCCTCGCCATGGACTCGGCCCTCAGCGATCCGCATAACGGCAGTGCCGAGGCAGGCGGCCCCAC
CAACAGCACTACGCGGCCGCCTTCCACGCCCGAGGGCATCGCGCTGGCCTACGGCAGCCTCCTGCTCATGGCGCTGCTGCCCATCTTCTT
CGGCGCCCTGCGCTCCGTACGCTGCGCCCGCGGCAAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGCCGCCCGCTTCCC
CATCATCGCCAGCTGCACACTCTTGGGGCTCTACCTCTTTTTCAAAGATACTTTTGTGGAACTCTATGGGAACAATGCAGCAGCCGAGAG
CCGAAAGGGCCAGGAACGCTTCAACCGCTGGTTCCTGACGGGCATGACTGTGGCCGGCGTGGTTCTGCTGGGCTCACTCTTCAGTCGGAA
ATGACCAGACACTGACCATCCACTCTACCCTCCCACCCCCTTCTCTGCTCCACCACATCCTCCGTCCAGCCGCCATTGCCACCAGGAGAA
CCACTACATGCAGCCCATGCCCACCTGCCCATCACAGGGTTGGGCCCAGATCTGGTCCCTTGCAGCTAGTTTTCTAGAATTTATCACACT
TCTGTGAGACCCCCACACCTCAGTTCCCTTGGCCTCAGAATTCACAAAATTTCCACAAAATCTGTCCAAAGGAGGCTGGCAGGTATGGAA
GGGTTTGTGGCTGGGGGCAGGAGGGCCCTACCTGATTGGTGCAACCCTTACCCCTTAGCCTCCCTGAAAATGTTTTTCTGCCAGGGAGCT
TGAAAGTTTTCAGAACCTCTTCCCCAGAAAGGAGACTAGATTGCCTTTGTTTTGATGTTTGTGGCCTCAGAATTGATCATTTTCCCCCCA
CTCTCCCCACACTAACCTGGGTTCCCTTTCCTTCCATCCCTACCCCCTAAGAGCCATTTAGGGGCCACTTTTGACTAGGGATTCAGGCTG
CTTGGGATAAAGATGCAAGGACCAGGACTCCCTCCTCACCTCTGGACTGGCTAGAGTCCTCACTCCCAGTCCAAATGTCCTCCAGAAGCC
TCTGGCTAGAGGCCAGCCCCACCCAGGAGGGAGGGGGCTATAGCTACAGGAAGCACCCCATGCCAAAGCTAGGGTGGCCCTTGCAGTTCA
GCACCACCCTAGTCCCTTCCCCTCCCTGGCTCCCATGACCATACTGAGGGACCAACTGGGCCCAAGACAGATGCCCCAGAGCTGTTTATG
GCCTCAGCTGCCTCACTTCCTACAAGAGCAGCCTGTGGCATCTTTGCCTTGGGCTGCTCCTCATGGTGGGTTCAGGGGACTCAGCCCTGA
GGTGAAAGGGAGCTATCAGGAACAGCTATGGGAGCCCCAGGGTCTTCCCTACCTCAGGCAGGAAGGGCAGGAAGGAGAGCCTGCTGCATG
GGGTGGGGTAGGGCTGACTAGAAGGGCCAGTCCTGCCTGGCCAGGCAGATCTGTGCCCCATGCCTGTCCAGCCTGGGCAGCCAGGCTGCC
AAGGCCAGAGTGGCCTGGCCAGGAGCTCTTCAGGCCTCCCTCTCTCTTCTGCTCCACCCTTGGCCTGTCTCATCCCCAGGGGTCCCAGCC
ACCCCGGGCTCTCTGCTGTACATATTTGAGACTAGTTTTTATTCCTTGTGAAGATGATATACTATTTTTGTTAAGCGTGTCTGTATTTAT
GTGTGAGGAGCTGCTGGCTTGCAGTGCGCGTGCACGTGGAGAGCTGGTGCCCGGAGATTGGACGGCCTGATGCTCCCTCCCCTGCCCTGG
TCCAGGGAAGCTGGCCGAGGGTCCTGGCTCCTGAGGGGCATCTGCCCCTCCCCCAACCCCCACCCCACACTTGTTCCAGCTCTTTGAAAT

>36744_36744_1_HM13-BCL2L1_HM13_chr20_30115385_ENST00000335574_BCL2L1_chr20_30253889_ENST00000376062_length(amino acids)=194AA_BP=
MAPMTILRDQLGPRQMPQSCLWPQLPHFLQEQPVASLPWAAPHGGFRGLSPEVKGSYQEQLWEPQGLPYLRQEGQEGEPAAWGGVGLTRR
ASPAWPGRSVPHACPAWAARLPRPEWPGQELFRPPSLFCSTLGLSHPQGSQPPRALCCTYLRLVFIPCEDDILFLLSVSVFMCEELLACS

--------------------------------------------------------------
>36744_36744_2_HM13-BCL2L1_HM13_chr20_30115385_ENST00000340852_BCL2L1_chr20_30253889_ENST00000376062_length(transcript)=2041nt_BP=406nt
GGAGGGAGCACGTCACTTCCTGTTGCCTTAGGGGAACGTGGCTTTCCCTGCAGAGCCGGTGTCTCCGCCTGCGTCCCTGCTGCAGCAACC
GGAGCTGGAGTCGGATCCCGAACGCACCCTCGCCATGGACTCGGCCCTCAGCGATCCGCATAACGGCAGTGCCGAGGCAGGCGGCCCCAC
CAACAGCACTACGCGGCCGCCTTCCACGCCCGAGGGCATCGCGCTGGCCTACGGCAGCCTCCTGCTCATGGCGCTGCTGCCCATCTTCTT
CGGCGCCCTGCGCTCCGTACGCTGCGCCCGCGGCAAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGCCGCCCGCTTCCC
CATCATCGCCAGCTGCACACTCTTGGGGCTCTACCTCTTTTTCAAAGATACTTTTGTGGAACTCTATGGGAACAATGCAGCAGCCGAGAG
CCGAAAGGGCCAGGAACGCTTCAACCGCTGGTTCCTGACGGGCATGACTGTGGCCGGCGTGGTTCTGCTGGGCTCACTCTTCAGTCGGAA
ATGACCAGACACTGACCATCCACTCTACCCTCCCACCCCCTTCTCTGCTCCACCACATCCTCCGTCCAGCCGCCATTGCCACCAGGAGAA
CCACTACATGCAGCCCATGCCCACCTGCCCATCACAGGGTTGGGCCCAGATCTGGTCCCTTGCAGCTAGTTTTCTAGAATTTATCACACT
TCTGTGAGACCCCCACACCTCAGTTCCCTTGGCCTCAGAATTCACAAAATTTCCACAAAATCTGTCCAAAGGAGGCTGGCAGGTATGGAA
GGGTTTGTGGCTGGGGGCAGGAGGGCCCTACCTGATTGGTGCAACCCTTACCCCTTAGCCTCCCTGAAAATGTTTTTCTGCCAGGGAGCT
TGAAAGTTTTCAGAACCTCTTCCCCAGAAAGGAGACTAGATTGCCTTTGTTTTGATGTTTGTGGCCTCAGAATTGATCATTTTCCCCCCA
CTCTCCCCACACTAACCTGGGTTCCCTTTCCTTCCATCCCTACCCCCTAAGAGCCATTTAGGGGCCACTTTTGACTAGGGATTCAGGCTG
CTTGGGATAAAGATGCAAGGACCAGGACTCCCTCCTCACCTCTGGACTGGCTAGAGTCCTCACTCCCAGTCCAAATGTCCTCCAGAAGCC
TCTGGCTAGAGGCCAGCCCCACCCAGGAGGGAGGGGGCTATAGCTACAGGAAGCACCCCATGCCAAAGCTAGGGTGGCCCTTGCAGTTCA
GCACCACCCTAGTCCCTTCCCCTCCCTGGCTCCCATGACCATACTGAGGGACCAACTGGGCCCAAGACAGATGCCCCAGAGCTGTTTATG
GCCTCAGCTGCCTCACTTCCTACAAGAGCAGCCTGTGGCATCTTTGCCTTGGGCTGCTCCTCATGGTGGGTTCAGGGGACTCAGCCCTGA
GGTGAAAGGGAGCTATCAGGAACAGCTATGGGAGCCCCAGGGTCTTCCCTACCTCAGGCAGGAAGGGCAGGAAGGAGAGCCTGCTGCATG
GGGTGGGGTAGGGCTGACTAGAAGGGCCAGTCCTGCCTGGCCAGGCAGATCTGTGCCCCATGCCTGTCCAGCCTGGGCAGCCAGGCTGCC
AAGGCCAGAGTGGCCTGGCCAGGAGCTCTTCAGGCCTCCCTCTCTCTTCTGCTCCACCCTTGGCCTGTCTCATCCCCAGGGGTCCCAGCC
ACCCCGGGCTCTCTGCTGTACATATTTGAGACTAGTTTTTATTCCTTGTGAAGATGATATACTATTTTTGTTAAGCGTGTCTGTATTTAT
GTGTGAGGAGCTGCTGGCTTGCAGTGCGCGTGCACGTGGAGAGCTGGTGCCCGGAGATTGGACGGCCTGATGCTCCCTCCCCTGCCCTGG
TCCAGGGAAGCTGGCCGAGGGTCCTGGCTCCTGAGGGGCATCTGCCCCTCCCCCAACCCCCACCCCACACTTGTTCCAGCTCTTTGAAAT

>36744_36744_2_HM13-BCL2L1_HM13_chr20_30115385_ENST00000340852_BCL2L1_chr20_30253889_ENST00000376062_length(amino acids)=194AA_BP=
MAPMTILRDQLGPRQMPQSCLWPQLPHFLQEQPVASLPWAAPHGGFRGLSPEVKGSYQEQLWEPQGLPYLRQEGQEGEPAAWGGVGLTRR
ASPAWPGRSVPHACPAWAARLPRPEWPGQELFRPPSLFCSTLGLSHPQGSQPPRALCCTYLRLVFIPCEDDILFLLSVSVFMCEELLACS

--------------------------------------------------------------
>36744_36744_3_HM13-BCL2L1_HM13_chr20_30115385_ENST00000376127_BCL2L1_chr20_30253889_ENST00000376062_length(transcript)=2010nt_BP=375nt
GGGAACGTGGCTTTCCCTGCAGAGCCGGTGTCTCCGCCTGCGTCCCTGCTGCAGCAACCGGAGCTGGAGTCGGATCCCGAACGCACCCTC
GCCATGGACTCGGCCCTCAGCGATCCGCATAACGGCAGTGCCGAGGCAGGCGGCCCCACCAACAGCACTACGCGGCCGCCTTCCACGCCC
GAGGGCATCGCGCTGGCCTACGGCAGCCTCCTGCTCATGGCGCTGCTGCCCATCTTCTTCGGCGCCCTGCGCTCCGTACGCTGCGCCCGC
GGCAAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGCCGCCCGCTTCCCCATCATCGCCAGCTGCACACTCTTGGGGCTC
TACCTCTTTTTCAAAGATACTTTTGTGGAACTCTATGGGAACAATGCAGCAGCCGAGAGCCGAAAGGGCCAGGAACGCTTCAACCGCTGG
TTCCTGACGGGCATGACTGTGGCCGGCGTGGTTCTGCTGGGCTCACTCTTCAGTCGGAAATGACCAGACACTGACCATCCACTCTACCCT
CCCACCCCCTTCTCTGCTCCACCACATCCTCCGTCCAGCCGCCATTGCCACCAGGAGAACCACTACATGCAGCCCATGCCCACCTGCCCA
TCACAGGGTTGGGCCCAGATCTGGTCCCTTGCAGCTAGTTTTCTAGAATTTATCACACTTCTGTGAGACCCCCACACCTCAGTTCCCTTG
GCCTCAGAATTCACAAAATTTCCACAAAATCTGTCCAAAGGAGGCTGGCAGGTATGGAAGGGTTTGTGGCTGGGGGCAGGAGGGCCCTAC
CTGATTGGTGCAACCCTTACCCCTTAGCCTCCCTGAAAATGTTTTTCTGCCAGGGAGCTTGAAAGTTTTCAGAACCTCTTCCCCAGAAAG
GAGACTAGATTGCCTTTGTTTTGATGTTTGTGGCCTCAGAATTGATCATTTTCCCCCCACTCTCCCCACACTAACCTGGGTTCCCTTTCC
TTCCATCCCTACCCCCTAAGAGCCATTTAGGGGCCACTTTTGACTAGGGATTCAGGCTGCTTGGGATAAAGATGCAAGGACCAGGACTCC
CTCCTCACCTCTGGACTGGCTAGAGTCCTCACTCCCAGTCCAAATGTCCTCCAGAAGCCTCTGGCTAGAGGCCAGCCCCACCCAGGAGGG
AGGGGGCTATAGCTACAGGAAGCACCCCATGCCAAAGCTAGGGTGGCCCTTGCAGTTCAGCACCACCCTAGTCCCTTCCCCTCCCTGGCT
CCCATGACCATACTGAGGGACCAACTGGGCCCAAGACAGATGCCCCAGAGCTGTTTATGGCCTCAGCTGCCTCACTTCCTACAAGAGCAG
CCTGTGGCATCTTTGCCTTGGGCTGCTCCTCATGGTGGGTTCAGGGGACTCAGCCCTGAGGTGAAAGGGAGCTATCAGGAACAGCTATGG
GAGCCCCAGGGTCTTCCCTACCTCAGGCAGGAAGGGCAGGAAGGAGAGCCTGCTGCATGGGGTGGGGTAGGGCTGACTAGAAGGGCCAGT
CCTGCCTGGCCAGGCAGATCTGTGCCCCATGCCTGTCCAGCCTGGGCAGCCAGGCTGCCAAGGCCAGAGTGGCCTGGCCAGGAGCTCTTC
AGGCCTCCCTCTCTCTTCTGCTCCACCCTTGGCCTGTCTCATCCCCAGGGGTCCCAGCCACCCCGGGCTCTCTGCTGTACATATTTGAGA
CTAGTTTTTATTCCTTGTGAAGATGATATACTATTTTTGTTAAGCGTGTCTGTATTTATGTGTGAGGAGCTGCTGGCTTGCAGTGCGCGT
GCACGTGGAGAGCTGGTGCCCGGAGATTGGACGGCCTGATGCTCCCTCCCCTGCCCTGGTCCAGGGAAGCTGGCCGAGGGTCCTGGCTCC
TGAGGGGCATCTGCCCCTCCCCCAACCCCCACCCCACACTTGTTCCAGCTCTTTGAAATAGTCTGTGTGAAGGTGAAAGTGCAGTTCAGT

>36744_36744_3_HM13-BCL2L1_HM13_chr20_30115385_ENST00000376127_BCL2L1_chr20_30253889_ENST00000376062_length(amino acids)=194AA_BP=
MAPMTILRDQLGPRQMPQSCLWPQLPHFLQEQPVASLPWAAPHGGFRGLSPEVKGSYQEQLWEPQGLPYLRQEGQEGEPAAWGGVGLTRR
ASPAWPGRSVPHACPAWAARLPRPEWPGQELFRPPSLFCSTLGLSHPQGSQPPRALCCTYLRLVFIPCEDDILFLLSVSVFMCEELLACS

--------------------------------------------------------------
>36744_36744_4_HM13-BCL2L1_HM13_chr20_30115385_ENST00000398174_BCL2L1_chr20_30253889_ENST00000376062_length(transcript)=2041nt_BP=406nt
GGAGGGAGCACGTCACTTCCTGTTGCCTTAGGGGAACGTGGCTTTCCCTGCAGAGCCGGTGTCTCCGCCTGCGTCCCTGCTGCAGCAACC
GGAGCTGGAGTCGGATCCCGAACGCACCCTCGCCATGGACTCGGCCCTCAGCGATCCGCATAACGGCAGTGCCGAGGCAGGCGGCCCCAC
CAACAGCACTACGCGGCCGCCTTCCACGCCCGAGGGCATCGCGCTGGCCTACGGCAGCCTCCTGCTCATGGCGCTGCTGCCCATCTTCTT
CGGCGCCCTGCGCTCCGTACGCTGCGCCCGCGGCAAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGCCGCCCGCTTCCC
CATCATCGCCAGCTGCACACTCTTGGGGCTCTACCTCTTTTTCAAAGATACTTTTGTGGAACTCTATGGGAACAATGCAGCAGCCGAGAG
CCGAAAGGGCCAGGAACGCTTCAACCGCTGGTTCCTGACGGGCATGACTGTGGCCGGCGTGGTTCTGCTGGGCTCACTCTTCAGTCGGAA
ATGACCAGACACTGACCATCCACTCTACCCTCCCACCCCCTTCTCTGCTCCACCACATCCTCCGTCCAGCCGCCATTGCCACCAGGAGAA
CCACTACATGCAGCCCATGCCCACCTGCCCATCACAGGGTTGGGCCCAGATCTGGTCCCTTGCAGCTAGTTTTCTAGAATTTATCACACT
TCTGTGAGACCCCCACACCTCAGTTCCCTTGGCCTCAGAATTCACAAAATTTCCACAAAATCTGTCCAAAGGAGGCTGGCAGGTATGGAA
GGGTTTGTGGCTGGGGGCAGGAGGGCCCTACCTGATTGGTGCAACCCTTACCCCTTAGCCTCCCTGAAAATGTTTTTCTGCCAGGGAGCT
TGAAAGTTTTCAGAACCTCTTCCCCAGAAAGGAGACTAGATTGCCTTTGTTTTGATGTTTGTGGCCTCAGAATTGATCATTTTCCCCCCA
CTCTCCCCACACTAACCTGGGTTCCCTTTCCTTCCATCCCTACCCCCTAAGAGCCATTTAGGGGCCACTTTTGACTAGGGATTCAGGCTG
CTTGGGATAAAGATGCAAGGACCAGGACTCCCTCCTCACCTCTGGACTGGCTAGAGTCCTCACTCCCAGTCCAAATGTCCTCCAGAAGCC
TCTGGCTAGAGGCCAGCCCCACCCAGGAGGGAGGGGGCTATAGCTACAGGAAGCACCCCATGCCAAAGCTAGGGTGGCCCTTGCAGTTCA
GCACCACCCTAGTCCCTTCCCCTCCCTGGCTCCCATGACCATACTGAGGGACCAACTGGGCCCAAGACAGATGCCCCAGAGCTGTTTATG
GCCTCAGCTGCCTCACTTCCTACAAGAGCAGCCTGTGGCATCTTTGCCTTGGGCTGCTCCTCATGGTGGGTTCAGGGGACTCAGCCCTGA
GGTGAAAGGGAGCTATCAGGAACAGCTATGGGAGCCCCAGGGTCTTCCCTACCTCAGGCAGGAAGGGCAGGAAGGAGAGCCTGCTGCATG
GGGTGGGGTAGGGCTGACTAGAAGGGCCAGTCCTGCCTGGCCAGGCAGATCTGTGCCCCATGCCTGTCCAGCCTGGGCAGCCAGGCTGCC
AAGGCCAGAGTGGCCTGGCCAGGAGCTCTTCAGGCCTCCCTCTCTCTTCTGCTCCACCCTTGGCCTGTCTCATCCCCAGGGGTCCCAGCC
ACCCCGGGCTCTCTGCTGTACATATTTGAGACTAGTTTTTATTCCTTGTGAAGATGATATACTATTTTTGTTAAGCGTGTCTGTATTTAT
GTGTGAGGAGCTGCTGGCTTGCAGTGCGCGTGCACGTGGAGAGCTGGTGCCCGGAGATTGGACGGCCTGATGCTCCCTCCCCTGCCCTGG
TCCAGGGAAGCTGGCCGAGGGTCCTGGCTCCTGAGGGGCATCTGCCCCTCCCCCAACCCCCACCCCACACTTGTTCCAGCTCTTTGAAAT

>36744_36744_4_HM13-BCL2L1_HM13_chr20_30115385_ENST00000398174_BCL2L1_chr20_30253889_ENST00000376062_length(amino acids)=194AA_BP=
MAPMTILRDQLGPRQMPQSCLWPQLPHFLQEQPVASLPWAAPHGGFRGLSPEVKGSYQEQLWEPQGLPYLRQEGQEGEPAAWGGVGLTRR
ASPAWPGRSVPHACPAWAARLPRPEWPGQELFRPPSLFCSTLGLSHPQGSQPPRALCCTYLRLVFIPCEDDILFLLSVSVFMCEELLACS

--------------------------------------------------------------
>36744_36744_5_HM13-BCL2L1_HM13_chr20_30126064_ENST00000335574_BCL2L1_chr20_30253889_ENST00000307677_length(transcript)=2124nt_BP=489nt
GGAGGGAGCACGTCACTTCCTGTTGCCTTAGGGGAACGTGGCTTTCCCTGCAGAGCCGGTGTCTCCGCCTGCGTCCCTGCTGCAGCAACC
GGAGCTGGAGTCGGATCCCGAACGCACCCTCGCCATGGACTCGGCCCTCAGCGATCCGCATAACGGCAGTGCCGAGGCAGGCGGCCCCAC
CAACAGCACTACGCGGCCGCCTTCCACGCCCGAGGGCATCGCGCTGGCCTACGGCAGCCTCCTGCTCATGGCGCTGCTGCCCATCTTCTT
CGGCGCCCTGCGCTCCGTACGCTGCGCCCGCGGCAAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGCCGCCCGCTTCCC
CATCATCGCCAGCTGCACACTCTTGGGGCTCTACCTCTTTTTCAAAATATTCTCCCAGGAGTACATCAACCTCCTGCTGTCCATGTATTT
CTTCGTGCTGGGAATCCTGGCCCTGTCCCACACCATCAGGATACTTTTGTGGAACTCTATGGGAACAATGCAGCAGCCGAGAGCCGAAAG
GGCCAGGAACGCTTCAACCGCTGGTTCCTGACGGGCATGACTGTGGCCGGCGTGGTTCTGCTGGGCTCACTCTTCAGTCGGAAATGACCA
GACACTGACCATCCACTCTACCCTCCCACCCCCTTCTCTGCTCCACCACATCCTCCGTCCAGCCGCCATTGCCACCAGGAGAACCACTAC
ATGCAGCCCATGCCCACCTGCCCATCACAGGGTTGGGCCCAGATCTGGTCCCTTGCAGCTAGTTTTCTAGAATTTATCACACTTCTGTGA
GACCCCCACACCTCAGTTCCCTTGGCCTCAGAATTCACAAAATTTCCACAAAATCTGTCCAAAGGAGGCTGGCAGGTATGGAAGGGTTTG
TGGCTGGGGGCAGGAGGGCCCTACCTGATTGGTGCAACCCTTACCCCTTAGCCTCCCTGAAAATGTTTTTCTGCCAGGGAGCTTGAAAGT
TTTCAGAACCTCTTCCCCAGAAAGGAGACTAGATTGCCTTTGTTTTGATGTTTGTGGCCTCAGAATTGATCATTTTCCCCCCACTCTCCC
CACACTAACCTGGGTTCCCTTTCCTTCCATCCCTACCCCCTAAGAGCCATTTAGGGGCCACTTTTGACTAGGGATTCAGGCTGCTTGGGA
TAAAGATGCAAGGACCAGGACTCCCTCCTCACCTCTGGACTGGCTAGAGTCCTCACTCCCAGTCCAAATGTCCTCCAGAAGCCTCTGGCT
AGAGGCCAGCCCCACCCAGGAGGGAGGGGGCTATAGCTACAGGAAGCACCCCATGCCAAAGCTAGGGTGGCCCTTGCAGTTCAGCACCAC
CCTAGTCCCTTCCCCTCCCTGGCTCCCATGACCATACTGAGGGACCAACTGGGCCCAAGACAGATGCCCCAGAGCTGTTTATGGCCTCAG
CTGCCTCACTTCCTACAAGAGCAGCCTGTGGCATCTTTGCCTTGGGCTGCTCCTCATGGTGGGTTCAGGGGACTCAGCCCTGAGGTGAAA
GGGAGCTATCAGGAACAGCTATGGGAGCCCCAGGGTCTTCCCTACCTCAGGCAGGAAGGGCAGGAAGGAGAGCCTGCTGCATGGGGTGGG
GTAGGGCTGACTAGAAGGGCCAGTCCTGCCTGGCCAGGCAGATCTGTGCCCCATGCCTGTCCAGCCTGGGCAGCCAGGCTGCCAAGGCCA
GAGTGGCCTGGCCAGGAGCTCTTCAGGCCTCCCTCTCTCTTCTGCTCCACCCTTGGCCTGTCTCATCCCCAGGGGTCCCAGCCACCCCGG
GCTCTCTGCTGTACATATTTGAGACTAGTTTTTATTCCTTGTGAAGATGATATACTATTTTTGTTAAGCGTGTCTGTATTTATGTGTGAG
GAGCTGCTGGCTTGCAGTGCGCGTGCACGTGGAGAGCTGGTGCCCGGAGATTGGACGGCCTGATGCTCCCTCCCCTGCCCTGGTCCAGGG
AAGCTGGCCGAGGGTCCTGGCTCCTGAGGGGCATCTGCCCCTCCCCCAACCCCCACCCCACACTTGTTCCAGCTCTTTGAAATAGTCTGT

>36744_36744_5_HM13-BCL2L1_HM13_chr20_30126064_ENST00000335574_BCL2L1_chr20_30253889_ENST00000307677_length(amino acids)=196AA_BP=141
MQSRCLRLRPCCSNRSWSRIPNAPSPWTRPSAIRITAVPRQAAPPTALRGRLPRPRASRWPTAASCSWRCCPSSSAPCAPYAAPAARMLQ
TCLKQSPAGMPPASPSSPAAHSWGSTSFSKYSPRSTSTSCCPCISSCWESWPCPTPSGYFCGTLWEQCSSREPKGPGTLQPLVPDGHDCG

--------------------------------------------------------------
>36744_36744_6_HM13-BCL2L1_HM13_chr20_30126064_ENST00000340852_BCL2L1_chr20_30253889_ENST00000307677_length(transcript)=2124nt_BP=489nt
GGAGGGAGCACGTCACTTCCTGTTGCCTTAGGGGAACGTGGCTTTCCCTGCAGAGCCGGTGTCTCCGCCTGCGTCCCTGCTGCAGCAACC
GGAGCTGGAGTCGGATCCCGAACGCACCCTCGCCATGGACTCGGCCCTCAGCGATCCGCATAACGGCAGTGCCGAGGCAGGCGGCCCCAC
CAACAGCACTACGCGGCCGCCTTCCACGCCCGAGGGCATCGCGCTGGCCTACGGCAGCCTCCTGCTCATGGCGCTGCTGCCCATCTTCTT
CGGCGCCCTGCGCTCCGTACGCTGCGCCCGCGGCAAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGCCGCCCGCTTCCC
CATCATCGCCAGCTGCACACTCTTGGGGCTCTACCTCTTTTTCAAAATATTCTCCCAGGAGTACATCAACCTCCTGCTGTCCATGTATTT
CTTCGTGCTGGGAATCCTGGCCCTGTCCCACACCATCAGGATACTTTTGTGGAACTCTATGGGAACAATGCAGCAGCCGAGAGCCGAAAG
GGCCAGGAACGCTTCAACCGCTGGTTCCTGACGGGCATGACTGTGGCCGGCGTGGTTCTGCTGGGCTCACTCTTCAGTCGGAAATGACCA
GACACTGACCATCCACTCTACCCTCCCACCCCCTTCTCTGCTCCACCACATCCTCCGTCCAGCCGCCATTGCCACCAGGAGAACCACTAC
ATGCAGCCCATGCCCACCTGCCCATCACAGGGTTGGGCCCAGATCTGGTCCCTTGCAGCTAGTTTTCTAGAATTTATCACACTTCTGTGA
GACCCCCACACCTCAGTTCCCTTGGCCTCAGAATTCACAAAATTTCCACAAAATCTGTCCAAAGGAGGCTGGCAGGTATGGAAGGGTTTG
TGGCTGGGGGCAGGAGGGCCCTACCTGATTGGTGCAACCCTTACCCCTTAGCCTCCCTGAAAATGTTTTTCTGCCAGGGAGCTTGAAAGT
TTTCAGAACCTCTTCCCCAGAAAGGAGACTAGATTGCCTTTGTTTTGATGTTTGTGGCCTCAGAATTGATCATTTTCCCCCCACTCTCCC
CACACTAACCTGGGTTCCCTTTCCTTCCATCCCTACCCCCTAAGAGCCATTTAGGGGCCACTTTTGACTAGGGATTCAGGCTGCTTGGGA
TAAAGATGCAAGGACCAGGACTCCCTCCTCACCTCTGGACTGGCTAGAGTCCTCACTCCCAGTCCAAATGTCCTCCAGAAGCCTCTGGCT
AGAGGCCAGCCCCACCCAGGAGGGAGGGGGCTATAGCTACAGGAAGCACCCCATGCCAAAGCTAGGGTGGCCCTTGCAGTTCAGCACCAC
CCTAGTCCCTTCCCCTCCCTGGCTCCCATGACCATACTGAGGGACCAACTGGGCCCAAGACAGATGCCCCAGAGCTGTTTATGGCCTCAG
CTGCCTCACTTCCTACAAGAGCAGCCTGTGGCATCTTTGCCTTGGGCTGCTCCTCATGGTGGGTTCAGGGGACTCAGCCCTGAGGTGAAA
GGGAGCTATCAGGAACAGCTATGGGAGCCCCAGGGTCTTCCCTACCTCAGGCAGGAAGGGCAGGAAGGAGAGCCTGCTGCATGGGGTGGG
GTAGGGCTGACTAGAAGGGCCAGTCCTGCCTGGCCAGGCAGATCTGTGCCCCATGCCTGTCCAGCCTGGGCAGCCAGGCTGCCAAGGCCA
GAGTGGCCTGGCCAGGAGCTCTTCAGGCCTCCCTCTCTCTTCTGCTCCACCCTTGGCCTGTCTCATCCCCAGGGGTCCCAGCCACCCCGG
GCTCTCTGCTGTACATATTTGAGACTAGTTTTTATTCCTTGTGAAGATGATATACTATTTTTGTTAAGCGTGTCTGTATTTATGTGTGAG
GAGCTGCTGGCTTGCAGTGCGCGTGCACGTGGAGAGCTGGTGCCCGGAGATTGGACGGCCTGATGCTCCCTCCCCTGCCCTGGTCCAGGG
AAGCTGGCCGAGGGTCCTGGCTCCTGAGGGGCATCTGCCCCTCCCCCAACCCCCACCCCACACTTGTTCCAGCTCTTTGAAATAGTCTGT

>36744_36744_6_HM13-BCL2L1_HM13_chr20_30126064_ENST00000340852_BCL2L1_chr20_30253889_ENST00000307677_length(amino acids)=196AA_BP=141
MQSRCLRLRPCCSNRSWSRIPNAPSPWTRPSAIRITAVPRQAAPPTALRGRLPRPRASRWPTAASCSWRCCPSSSAPCAPYAAPAARMLQ
TCLKQSPAGMPPASPSSPAAHSWGSTSFSKYSPRSTSTSCCPCISSCWESWPCPTPSGYFCGTLWEQCSSREPKGPGTLQPLVPDGHDCG

--------------------------------------------------------------
>36744_36744_7_HM13-BCL2L1_HM13_chr20_30126064_ENST00000376127_BCL2L1_chr20_30253889_ENST00000307677_length(transcript)=2093nt_BP=458nt
GGGAACGTGGCTTTCCCTGCAGAGCCGGTGTCTCCGCCTGCGTCCCTGCTGCAGCAACCGGAGCTGGAGTCGGATCCCGAACGCACCCTC
GCCATGGACTCGGCCCTCAGCGATCCGCATAACGGCAGTGCCGAGGCAGGCGGCCCCACCAACAGCACTACGCGGCCGCCTTCCACGCCC
GAGGGCATCGCGCTGGCCTACGGCAGCCTCCTGCTCATGGCGCTGCTGCCCATCTTCTTCGGCGCCCTGCGCTCCGTACGCTGCGCCCGC
GGCAAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGCCGCCCGCTTCCCCATCATCGCCAGCTGCACACTCTTGGGGCTC
TACCTCTTTTTCAAAATATTCTCCCAGGAGTACATCAACCTCCTGCTGTCCATGTATTTCTTCGTGCTGGGAATCCTGGCCCTGTCCCAC
ACCATCAGGATACTTTTGTGGAACTCTATGGGAACAATGCAGCAGCCGAGAGCCGAAAGGGCCAGGAACGCTTCAACCGCTGGTTCCTGA
CGGGCATGACTGTGGCCGGCGTGGTTCTGCTGGGCTCACTCTTCAGTCGGAAATGACCAGACACTGACCATCCACTCTACCCTCCCACCC
CCTTCTCTGCTCCACCACATCCTCCGTCCAGCCGCCATTGCCACCAGGAGAACCACTACATGCAGCCCATGCCCACCTGCCCATCACAGG
GTTGGGCCCAGATCTGGTCCCTTGCAGCTAGTTTTCTAGAATTTATCACACTTCTGTGAGACCCCCACACCTCAGTTCCCTTGGCCTCAG
AATTCACAAAATTTCCACAAAATCTGTCCAAAGGAGGCTGGCAGGTATGGAAGGGTTTGTGGCTGGGGGCAGGAGGGCCCTACCTGATTG
GTGCAACCCTTACCCCTTAGCCTCCCTGAAAATGTTTTTCTGCCAGGGAGCTTGAAAGTTTTCAGAACCTCTTCCCCAGAAAGGAGACTA
GATTGCCTTTGTTTTGATGTTTGTGGCCTCAGAATTGATCATTTTCCCCCCACTCTCCCCACACTAACCTGGGTTCCCTTTCCTTCCATC
CCTACCCCCTAAGAGCCATTTAGGGGCCACTTTTGACTAGGGATTCAGGCTGCTTGGGATAAAGATGCAAGGACCAGGACTCCCTCCTCA
CCTCTGGACTGGCTAGAGTCCTCACTCCCAGTCCAAATGTCCTCCAGAAGCCTCTGGCTAGAGGCCAGCCCCACCCAGGAGGGAGGGGGC
TATAGCTACAGGAAGCACCCCATGCCAAAGCTAGGGTGGCCCTTGCAGTTCAGCACCACCCTAGTCCCTTCCCCTCCCTGGCTCCCATGA
CCATACTGAGGGACCAACTGGGCCCAAGACAGATGCCCCAGAGCTGTTTATGGCCTCAGCTGCCTCACTTCCTACAAGAGCAGCCTGTGG
CATCTTTGCCTTGGGCTGCTCCTCATGGTGGGTTCAGGGGACTCAGCCCTGAGGTGAAAGGGAGCTATCAGGAACAGCTATGGGAGCCCC
AGGGTCTTCCCTACCTCAGGCAGGAAGGGCAGGAAGGAGAGCCTGCTGCATGGGGTGGGGTAGGGCTGACTAGAAGGGCCAGTCCTGCCT
GGCCAGGCAGATCTGTGCCCCATGCCTGTCCAGCCTGGGCAGCCAGGCTGCCAAGGCCAGAGTGGCCTGGCCAGGAGCTCTTCAGGCCTC
CCTCTCTCTTCTGCTCCACCCTTGGCCTGTCTCATCCCCAGGGGTCCCAGCCACCCCGGGCTCTCTGCTGTACATATTTGAGACTAGTTT
TTATTCCTTGTGAAGATGATATACTATTTTTGTTAAGCGTGTCTGTATTTATGTGTGAGGAGCTGCTGGCTTGCAGTGCGCGTGCACGTG
GAGAGCTGGTGCCCGGAGATTGGACGGCCTGATGCTCCCTCCCCTGCCCTGGTCCAGGGAAGCTGGCCGAGGGTCCTGGCTCCTGAGGGG
CATCTGCCCCTCCCCCAACCCCCACCCCACACTTGTTCCAGCTCTTTGAAATAGTCTGTGTGAAGGTGAAAGTGCAGTTCAGTAATAAAC

>36744_36744_7_HM13-BCL2L1_HM13_chr20_30126064_ENST00000376127_BCL2L1_chr20_30253889_ENST00000307677_length(amino acids)=196AA_BP=141
MQSRCLRLRPCCSNRSWSRIPNAPSPWTRPSAIRITAVPRQAAPPTALRGRLPRPRASRWPTAASCSWRCCPSSSAPCAPYAAPAARMLQ
TCLKQSPAGMPPASPSSPAAHSWGSTSFSKYSPRSTSTSCCPCISSCWESWPCPTPSGYFCGTLWEQCSSREPKGPGTLQPLVPDGHDCG

--------------------------------------------------------------
>36744_36744_8_HM13-BCL2L1_HM13_chr20_30126064_ENST00000398174_BCL2L1_chr20_30253889_ENST00000307677_length(transcript)=2124nt_BP=489nt
GGAGGGAGCACGTCACTTCCTGTTGCCTTAGGGGAACGTGGCTTTCCCTGCAGAGCCGGTGTCTCCGCCTGCGTCCCTGCTGCAGCAACC
GGAGCTGGAGTCGGATCCCGAACGCACCCTCGCCATGGACTCGGCCCTCAGCGATCCGCATAACGGCAGTGCCGAGGCAGGCGGCCCCAC
CAACAGCACTACGCGGCCGCCTTCCACGCCCGAGGGCATCGCGCTGGCCTACGGCAGCCTCCTGCTCATGGCGCTGCTGCCCATCTTCTT
CGGCGCCCTGCGCTCCGTACGCTGCGCCCGCGGCAAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGCCGCCCGCTTCCC
CATCATCGCCAGCTGCACACTCTTGGGGCTCTACCTCTTTTTCAAAATATTCTCCCAGGAGTACATCAACCTCCTGCTGTCCATGTATTT
CTTCGTGCTGGGAATCCTGGCCCTGTCCCACACCATCAGGATACTTTTGTGGAACTCTATGGGAACAATGCAGCAGCCGAGAGCCGAAAG
GGCCAGGAACGCTTCAACCGCTGGTTCCTGACGGGCATGACTGTGGCCGGCGTGGTTCTGCTGGGCTCACTCTTCAGTCGGAAATGACCA
GACACTGACCATCCACTCTACCCTCCCACCCCCTTCTCTGCTCCACCACATCCTCCGTCCAGCCGCCATTGCCACCAGGAGAACCACTAC
ATGCAGCCCATGCCCACCTGCCCATCACAGGGTTGGGCCCAGATCTGGTCCCTTGCAGCTAGTTTTCTAGAATTTATCACACTTCTGTGA
GACCCCCACACCTCAGTTCCCTTGGCCTCAGAATTCACAAAATTTCCACAAAATCTGTCCAAAGGAGGCTGGCAGGTATGGAAGGGTTTG
TGGCTGGGGGCAGGAGGGCCCTACCTGATTGGTGCAACCCTTACCCCTTAGCCTCCCTGAAAATGTTTTTCTGCCAGGGAGCTTGAAAGT
TTTCAGAACCTCTTCCCCAGAAAGGAGACTAGATTGCCTTTGTTTTGATGTTTGTGGCCTCAGAATTGATCATTTTCCCCCCACTCTCCC
CACACTAACCTGGGTTCCCTTTCCTTCCATCCCTACCCCCTAAGAGCCATTTAGGGGCCACTTTTGACTAGGGATTCAGGCTGCTTGGGA
TAAAGATGCAAGGACCAGGACTCCCTCCTCACCTCTGGACTGGCTAGAGTCCTCACTCCCAGTCCAAATGTCCTCCAGAAGCCTCTGGCT
AGAGGCCAGCCCCACCCAGGAGGGAGGGGGCTATAGCTACAGGAAGCACCCCATGCCAAAGCTAGGGTGGCCCTTGCAGTTCAGCACCAC
CCTAGTCCCTTCCCCTCCCTGGCTCCCATGACCATACTGAGGGACCAACTGGGCCCAAGACAGATGCCCCAGAGCTGTTTATGGCCTCAG
CTGCCTCACTTCCTACAAGAGCAGCCTGTGGCATCTTTGCCTTGGGCTGCTCCTCATGGTGGGTTCAGGGGACTCAGCCCTGAGGTGAAA
GGGAGCTATCAGGAACAGCTATGGGAGCCCCAGGGTCTTCCCTACCTCAGGCAGGAAGGGCAGGAAGGAGAGCCTGCTGCATGGGGTGGG
GTAGGGCTGACTAGAAGGGCCAGTCCTGCCTGGCCAGGCAGATCTGTGCCCCATGCCTGTCCAGCCTGGGCAGCCAGGCTGCCAAGGCCA
GAGTGGCCTGGCCAGGAGCTCTTCAGGCCTCCCTCTCTCTTCTGCTCCACCCTTGGCCTGTCTCATCCCCAGGGGTCCCAGCCACCCCGG
GCTCTCTGCTGTACATATTTGAGACTAGTTTTTATTCCTTGTGAAGATGATATACTATTTTTGTTAAGCGTGTCTGTATTTATGTGTGAG
GAGCTGCTGGCTTGCAGTGCGCGTGCACGTGGAGAGCTGGTGCCCGGAGATTGGACGGCCTGATGCTCCCTCCCCTGCCCTGGTCCAGGG
AAGCTGGCCGAGGGTCCTGGCTCCTGAGGGGCATCTGCCCCTCCCCCAACCCCCACCCCACACTTGTTCCAGCTCTTTGAAATAGTCTGT

>36744_36744_8_HM13-BCL2L1_HM13_chr20_30126064_ENST00000398174_BCL2L1_chr20_30253889_ENST00000307677_length(amino acids)=196AA_BP=141
MQSRCLRLRPCCSNRSWSRIPNAPSPWTRPSAIRITAVPRQAAPPTALRGRLPRPRASRWPTAASCSWRCCPSSSAPCAPYAAPAARMLQ
TCLKQSPAGMPPASPSSPAAHSWGSTSFSKYSPRSTSTSCCPCISSCWESWPCPTPSGYFCGTLWEQCSSREPKGPGTLQPLVPDGHDCG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for HM13-BCL2L1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for HM13-BCL2L1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for HM13-BCL2L1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0019207Hepatoma, Morris2CTD_human
TgeneC0019208Hepatoma, Novikoff2CTD_human
TgeneC0023904Liver Neoplasms, Experimental2CTD_human
TgeneC0086404Experimental Hepatoma2CTD_human
TgeneC2239176Liver carcinoma2CTD_human
TgeneC0001430Adenoma1CTD_human
TgeneC0002152Alloxan Diabetes1CTD_human
TgeneC0007097Carcinoma1CTD_human
TgeneC0010417Cryptorchidism1CTD_human
TgeneC0011853Diabetes Mellitus, Experimental1CTD_human
TgeneC0011860Diabetes Mellitus, Non-Insulin-Dependent1CTD_human
TgeneC0018671Head and Neck Neoplasms1CTD_human
TgeneC0018675Head Neoplasms1CTD_human
TgeneC0023895Liver diseases1CTD_human
TgeneC0024121Lung Neoplasms1CTD_human
TgeneC0024623Malignant neoplasm of stomach1CTD_human
TgeneC0026764Multiple Myeloma1CTD_human
TgeneC0027051Myocardial Infarction1CTD_human
TgeneC0027533Neck Neoplasms1CTD_human
TgeneC0030297Pancreatic Neoplasm1CTD_human
TgeneC0038356Stomach Neoplasms1CTD_human
TgeneC0038433Streptozotocin Diabetes1CTD_human
TgeneC0086565Liver Dysfunction1CTD_human
TgeneC0149504Encephalopathy, Toxic1CTD_human
TgeneC0154659Toxic Encephalitis1CTD_human
TgeneC0205646Adenoma, Basal Cell1CTD_human
TgeneC0205647Follicular adenoma1CTD_human
TgeneC0205648Adenoma, Microcystic1CTD_human
TgeneC0205649Adenoma, Monomorphic1CTD_human
TgeneC0205650Papillary adenoma1CTD_human
TgeneC0205651Adenoma, Trabecular1CTD_human
TgeneC0205696Anaplastic carcinoma1CTD_human
TgeneC0205697Carcinoma, Spindle-Cell1CTD_human
TgeneC0205698Undifferentiated carcinoma1CTD_human
TgeneC0205699Carcinomatosis1CTD_human
TgeneC0235032Neurotoxicity Syndromes1CTD_human
TgeneC0242350Erectile dysfunction1CTD_human
TgeneC0242379Malignant neoplasm of lung1CTD_human
TgeneC0278996Malignant Head and Neck Neoplasm1CTD_human
TgeneC0346647Malignant neoplasm of pancreas1CTD_human
TgeneC0431663Bilateral Cryptorchidism1CTD_human
TgeneC0431664Unilateral Cryptorchidism1CTD_human
TgeneC0746787Cancer of Neck1CTD_human
TgeneC0751177Cancer of Head1CTD_human
TgeneC0887900Upper Aerodigestive Tract Neoplasms1CTD_human
TgeneC1384666hearing impairment1CTD_human
TgeneC1563730Abdominal Cryptorchidism1CTD_human
TgeneC1563731Inguinal Cryptorchidism1CTD_human
TgeneC1708349Hereditary Diffuse Gastric Cancer1CTD_human
TgeneC1862939AMYOTROPHIC LATERAL SCLEROSIS 11CTD_human
TgeneC1862941Amyotrophic Lateral Sclerosis, Sporadic1CTD_human
TgeneC2937358Cerebral Hemorrhage1CTD_human
TgeneC4551993Amyotrophic Lateral Sclerosis, Familial1CTD_human