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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:USP34-FAM161A (FusionGDB2 ID:HG9736TG84140) |
Fusion Gene Summary for USP34-FAM161A |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: USP34-FAM161A | Fusion gene ID: hg9736tg84140 | Hgene | Tgene | Gene symbol | USP34 | FAM161A | Gene ID | 9736 | 84140 |
| Gene name | ubiquitin specific peptidase 34 | FAM161 centrosomal protein A | |
| Synonyms | - | RP28 | |
| Cytomap | ('USP34')('FAM161A') 2p15 | 2p15 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ubiquitin carboxyl-terminal hydrolase 34deubiquitinating enzyme 34ubiquitin specific protease 34ubiquitin thioesterase 34ubiquitin thiolesterase 34ubiquitin-specific-processing protease 34 | protein FAM161AFAM161A, centrosomal proteinfamily with sequence similarity 161 member Aretinitis pigmentosa 28 (autosomal recessive) | |
| Modification date | 20200313 | 20200327 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000398571, ENST00000472689, | ||
| Fusion gene scores | * DoF score | 30 X 29 X 14=12180 | 3 X 4 X 3=36 |
| # samples | 37 | 4 | |
| ** MAII score | log2(37/12180*10)=-5.04084505227738 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: USP34 [Title/Abstract] AND FAM161A [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | USP34(61486846)-FAM161A(62054393), # samples:4 | ||
| Anticipated loss of major functional domain due to fusion event. | USP34-FAM161A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. USP34-FAM161A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. USP34-FAM161A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. USP34-FAM161A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | USP34 | GO:0016579 | protein deubiquitination | 14715245 |
| Hgene | USP34 | GO:0071108 | protein K48-linked deubiquitination | 21383061 |
| Hgene | USP34 | GO:0090263 | positive regulation of canonical Wnt signaling pathway | 21383061 |
| Tgene | FAM161A | GO:1901985 | positive regulation of protein acetylation | 22791751 |
| Fusion gene breakpoints across USP34 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across FAM161A (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BLCA | TCGA-BL-A13J-01A | USP34 | chr2 | 61486846 | - | FAM161A | chr2 | 62054393 | - |
| ChimerDB4 | BLCA | TCGA-BL-A13J-01B | USP34 | chr2 | 61486846 | - | FAM161A | chr2 | 62054393 | - |
| ChimerDB4 | STAD | TCGA-BR-A4QI-01A | USP34 | chr2 | 61597456 | - | FAM161A | chr2 | 62069495 | - |
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Fusion Gene ORF analysis for USP34-FAM161A |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000398571 | ENST00000404929 | USP34 | chr2 | 61486846 | - | FAM161A | chr2 | 62054393 | - |
| In-frame | ENST00000398571 | ENST00000404929 | USP34 | chr2 | 61597456 | - | FAM161A | chr2 | 62069495 | - |
| In-frame | ENST00000398571 | ENST00000405894 | USP34 | chr2 | 61486846 | - | FAM161A | chr2 | 62054393 | - |
| In-frame | ENST00000398571 | ENST00000405894 | USP34 | chr2 | 61597456 | - | FAM161A | chr2 | 62069495 | - |
| intron-3CDS | ENST00000472689 | ENST00000404929 | USP34 | chr2 | 61486846 | - | FAM161A | chr2 | 62054393 | - |
| intron-3CDS | ENST00000472689 | ENST00000404929 | USP34 | chr2 | 61597456 | - | FAM161A | chr2 | 62069495 | - |
| intron-3CDS | ENST00000472689 | ENST00000405894 | USP34 | chr2 | 61486846 | - | FAM161A | chr2 | 62054393 | - |
| intron-3CDS | ENST00000472689 | ENST00000405894 | USP34 | chr2 | 61597456 | - | FAM161A | chr2 | 62069495 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000398571 | USP34 | chr2 | 61486846 | - | ENST00000404929 | FAM161A | chr2 | 62054393 | - | 7820 | 5921 | 77 | 6220 | 2047 |
| ENST00000398571 | USP34 | chr2 | 61486846 | - | ENST00000405894 | FAM161A | chr2 | 62054393 | - | 7820 | 5921 | 77 | 6220 | 2047 |
| ENST00000398571 | USP34 | chr2 | 61597456 | - | ENST00000404929 | FAM161A | chr2 | 62069495 | - | 4895 | 1328 | 77 | 3295 | 1072 |
| ENST00000398571 | USP34 | chr2 | 61597456 | - | ENST00000405894 | FAM161A | chr2 | 62069495 | - | 4727 | 1328 | 77 | 3127 | 1016 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000398571 | ENST00000404929 | USP34 | chr2 | 61486846 | - | FAM161A | chr2 | 62054393 | - | 0.000403067 | 0.9995969 |
| ENST00000398571 | ENST00000405894 | USP34 | chr2 | 61486846 | - | FAM161A | chr2 | 62054393 | - | 0.000403067 | 0.9995969 |
| ENST00000398571 | ENST00000404929 | USP34 | chr2 | 61597456 | - | FAM161A | chr2 | 62069495 | - | 0.000147636 | 0.9998523 |
| ENST00000398571 | ENST00000405894 | USP34 | chr2 | 61597456 | - | FAM161A | chr2 | 62069495 | - | 0.000140614 | 0.99985933 |
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Fusion Genomic Features for USP34-FAM161A |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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Fusion Protein Features for USP34-FAM161A |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:61486846/chr2:62054393) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | FAM161A | chr2:61597456 | chr2:62069495 | ENST00000404929 | 0 | 7 | 296_320 | 61 | 717.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | FAM161A | chr2:61597456 | chr2:62069495 | ENST00000404929 | 0 | 7 | 522_552 | 61 | 717.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | FAM161A | chr2:61597456 | chr2:62069495 | ENST00000404929 | 0 | 7 | 93_120 | 61 | 717.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | FAM161A | chr2:61597456 | chr2:62069495 | ENST00000405894 | 0 | 6 | 296_320 | 61 | 661.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | FAM161A | chr2:61597456 | chr2:62069495 | ENST00000405894 | 0 | 6 | 522_552 | 61 | 661.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | FAM161A | chr2:61597456 | chr2:62069495 | ENST00000405894 | 0 | 6 | 93_120 | 61 | 661.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | FAM161A | chr2:61486846 | chr2:62054393 | ENST00000405894 | 3 | 6 | 609_658 | 561 | 661.0 | Compositional bias | Note=Glu-rich | |
| Tgene | FAM161A | chr2:61597456 | chr2:62069495 | ENST00000404929 | 0 | 7 | 609_658 | 61 | 717.0 | Compositional bias | Note=Glu-rich | |
| Tgene | FAM161A | chr2:61597456 | chr2:62069495 | ENST00000405894 | 0 | 6 | 609_658 | 61 | 661.0 | Compositional bias | Note=Glu-rich |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | USP34 | chr2:61486846 | chr2:62054393 | ENST00000398571 | - | 44 | 80 | 1894_2239 | 1948 | 3547.0 | Domain | Note=USP |
| Hgene | USP34 | chr2:61597456 | chr2:62069495 | ENST00000398571 | - | 10 | 80 | 1894_2239 | 417 | 3547.0 | Domain | Note=USP |
| Tgene | FAM161A | chr2:61486846 | chr2:62054393 | ENST00000404929 | 4 | 7 | 296_320 | 617 | 717.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | FAM161A | chr2:61486846 | chr2:62054393 | ENST00000404929 | 4 | 7 | 522_552 | 617 | 717.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | FAM161A | chr2:61486846 | chr2:62054393 | ENST00000404929 | 4 | 7 | 93_120 | 617 | 717.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | FAM161A | chr2:61486846 | chr2:62054393 | ENST00000405894 | 3 | 6 | 296_320 | 561 | 661.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | FAM161A | chr2:61486846 | chr2:62054393 | ENST00000405894 | 3 | 6 | 522_552 | 561 | 661.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | FAM161A | chr2:61486846 | chr2:62054393 | ENST00000405894 | 3 | 6 | 93_120 | 561 | 661.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | FAM161A | chr2:61486846 | chr2:62054393 | ENST00000404929 | 4 | 7 | 47_52 | 617 | 717.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | FAM161A | chr2:61486846 | chr2:62054393 | ENST00000404929 | 4 | 7 | 609_658 | 617 | 717.0 | Compositional bias | Note=Glu-rich | |
| Tgene | FAM161A | chr2:61486846 | chr2:62054393 | ENST00000405894 | 3 | 6 | 47_52 | 561 | 661.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | FAM161A | chr2:61597456 | chr2:62069495 | ENST00000404929 | 0 | 7 | 47_52 | 61 | 717.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | FAM161A | chr2:61597456 | chr2:62069495 | ENST00000405894 | 0 | 6 | 47_52 | 61 | 661.0 | Compositional bias | Note=Poly-Glu |
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Fusion Gene Sequence for USP34-FAM161A |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >97395_97395_1_USP34-FAM161A_USP34_chr2_61486846_ENST00000398571_FAM161A_chr2_62054393_ENST00000404929_length(transcript)=7820nt_BP=5921nt TCTCTCCCCTCCCCCCCGCCGGTCGGGATCAGTCAGTGTGATCCGAAGCGGGGGAGGGGGGGGGCGGCGGCCGAACGATGTGCGAGAACT GCGCAGACCTGGTGGAGGTGTTAAATGAAATATCAGATGTAGAAGGTGGTGATGGACTGCAGCTCAGAAAGGAACATACTCTCAAAATAT TTACTTATATCAATTCCTGGACACAGAGGCAATGTCTATGCTGCTTCAAGGAATATAAGCATTTGGAGATTTTTAATCAAGTAGTGTGTG CACTTATTAACTTAGTGATTGCCCAAGTTCAAGTGCTCCGGGACCAGCTTTGTAAACATTGTACTACCATTAACATAGATTCCACGTGGC AAGATGAGAGTAATCAAGCAGAAGAACCACTGAATATAGATAGAGAGTGTAATGAAGGAAGTACAGAAAGACAAAAATCAATAGAAAAAA AATCAAACTCTACAAGAATTTGTAATCTGACTGAGGAGGAATCTTCAAAGAGTTCTGATCCTTTTAGTTTATGGAGTACAGATGAGAAGG AAAAACTCTTACTATGTGTGGCAAAAATTTTTCAAATTCAGTTTCCCTTATATACTGCTTACAAGCATAATACTCACCCTACTATTGAGG ATATATCAACTCAAGAAAGTAACATATTAGGGGCATTCTGTGATATGAATGATGTAGAAGTACCATTGCATTTGCTTCGTTATGTATGTT TGTTTTGTGGGAAAAATGGCCTTTCTCTCATGAAGGATTGCTTTGAATATGGAACTCCTGAAACTTTGCCATTTCTTATAGCACATGCGT TTATTACAGTTGTGTCTAATATTAGAATATGGCTACATATTCCCGCTGTCATGCAGCACATTATACCTTTTAGGACCTATGTTATTAGGT ATTTATGCAAGCTCTCGGATCAGGAGTTACGACAGAGTGCAGCTCGTAACATGGCTGACTTAATGTGGAGCACAGTCAAAGAACCATTGG ATACAACATTATGCTTTGATAAAGAAAGCCTAGATCTTGCATTTAAGTACTTTATGTCACCTACTTTGACTATGAGGTTGGCTGGATTGA GTCAGATAACAAATCAACTCCATACCTTCAATGATGTGTGCAATAATGAATCATTAGTATCGGACACAGAAACGTCCATTGCAAAAGAAC TTGCAGACTGGCTTATTAGCAACAATGTGGTGGAGCATATATTTGGACCAAATTTACATATTGAGATTATCAAACAGTGCCAAGTGATTT TGAATTTTTTGGCAGCAGAAGGGCGACTGAGTACTCAACATATTGACTGTATTTGGGCTGCAGCACAGTTGAAACATTGTAGTCGGTATA TACATGACTTATTTCCTTCACTCATCAAGAATTTGGATCCCGTACCACTTAGACATCTACTTAATCTGGTCTCAGCTCTTGAGCCAAGTG TTCATACTGAACAGACACTGTACTTGGCATCCATGTTAATTAAAGCACTGTGGAATAACGCACTAGCAGCTAAGGCTCAGTTATCTAAAC AGAGTTCTTTTGCATCTTTATTAAATACTAATATTCCCATTGGAAATAAGAAAGAGGAAGAAGAGCTTAGAAGAACAGCTCCATCACCTT GGTCACCTGCAGCTAGTCCTCAAAGCAGTGATAATAGCGATACACATCAAAGTGGAGGTAGTGACATTGAAATGGATGAGCAACTTATTA ATAGAACCAAACATGTGCAACAACGACTTTCAGACACAGAGGAATCCATGCAGGGAAGTTCTGACGAAACTGCCAACAGTGGTGAAGATG GAAGCAGTGGTCCTGGTAGCAGTAGTGGGCATAGTGATGGATCTAGCAATGAGGTTAATTCTAGCCACGCAAGCCAGTCAGCTGGGAGCC CTGGCAGTGAGGTACAGTCAGAAGACATTGCAGATATTGAAGCCCTCAAAGAGGAAGATGAAGACGATGATCATGGTCATAATCCTCCCA AAAGCAGTTGTGGTACAGATCTTCGGAATAGAAAGTTAGAGAGTCAAGCAGGCATTTGCCTGGGGGACTCCCAAGGCATGTCAGAAAGAA ATGGGACAAGCAGCGGAACAGGAAAGGACCTGGTTTTTAACACTGAATCATTGCCATCAGTAGATAATCGAATGCGAATGCTGGATGCTT GTTCACACTCTGAAGACCCAGAACATGATATTTCAGGGGAAATGAATGCTACTCATATAGCACAAGGGTCTCAGGAGTCTTGTATCACAC GAACTGGGGACTTCCTTGGGGAGACTATTGGGAATGAATTATTTAATTGTCGACAATTTATTGGTCCACAGCATCACCACCACCACCACC ACCATCACCACCACCACGATGGGCATATGGTTGATGATATGCTAAGTGCAGATGATGTCAGTTGTAGTAGCTCCCAGGTTAGTGCAAAAT CAGAAAAAAATATGGCTGATTTTGATGGTGAAGAATCTGGATGTGAAGAGGAGCTAGTTCAGATTAATTCACATGCGGAACTGACATCTC ACCTCCAACAACATCTTCCCAATTTAGCTTCCATTTACCATGAACATCTTAGTCAAGGACCTGTAGTTCATAAACATCAATTCAACAGTA ATGCTGTTACAGACATTAATTTGGATAATGTTTGCAAGAAAGGAAATACTTTGTTGTGGGATATAGTCCAAGATGAAGATGCAGTTAATC TTTCTGAAGGATTAATAAATGAAGCAGAGAAACTTCTTTGTTCGTTAGTATGTTGGTTTACAGATAGACAAATTCGAATGAGATTCATTG AAGGTTGCCTTGAAAACTTGGGAAACAACAGATCAGTAGTAATTTCACTTCGTCTTCTTCCAAAACTATTTGGTACTTTTCAGCAGTTTG GGAGCAGTTACGATACACACTGGATAACAATGTGGGCAGAAAAAGAACTGAACATGATGAAGCTTTTCTTTGATAATTTGGTATACTACA TTCAAACTGTGAGAGAAGGAAGACAAAAACATGCACTGTACAGCCATAGTGCTGAAGTTCAAGTTCGTCTTCAATTCTTGACTTGTGTAT TTTCAACTCTGGGATCACCTGATCATTTCAGGTTAAGTTTAGAGCAAGTTGACATCTTATGGCATTGTTTAGTAGAAGATTCTGAATGTT ATGATGATGCACTCCATTGGTTTTTAAATCAAGTTCGAAGTAAAGATCAACATGCTATGGGTATGGAAACCTACAAACATCTTTTCCTGG AGAAGATGCCCCAGCTAAAACCTGAAACAATTAGCATGACTGGCTTAAACCTGTTTCAGCATCTCTGTAACTTGGCTCGATTGGCTACCA GTGCCTATGATGGTTGTTCAAATTCTGAGCTGTGTGGTATGGACCAATTTTGGGGCATTGCTTTAAGAGCACAATCTGGTGATGTCAGTC GAGCAGCTATCCAGTATATTAACTCCTATTATATTAATGGTAAAACAGGTTTGGAGAAGGAGCAAGAATTTATTAGTAAGTGCATGGAGA GTCTTATGATAGCTTCTAGCAGTCTTGAACAGGAATCACACTCAAGTCTCATGGTTATAGAAAGAGGACTCCTTATGCTGAAGACACATC TGGAAGCGTTTAGGAGAAGGTTTGCATATCATCTGAGACAGTGGCAAATTGAAGGCACTGGTATTAGTAGTCATTTGAAAGCACTGAGTG ACAAACAGTCTCTGCCGCTAAGGGTTGTATGCCAGCCAGCTGGACTTCCTGACAAGATGACTATTGAAATGTATCCTAGTGACCAGGTAG CAGATCTTAGGGCTGAAGTAACTCATTGGTATGAAAATTTACAGAAAGAACAAATAAATCAACAAGCTCAGCTTCAGGAGTTTGGTCAAA GCAACCGAAAAGGAGAGTTTCCTGGAGGCCTCATGGGACCTGTCAGGATGATTTCATCTGGACACGAGTTAACAACAGATTATGATGAAA AAGCACTTCATGAGCTTGGTTTTAAGGATATGCAGATGGTATTTGTATCTTTGGGTGCACCAAGGAGAGAGCGGAAAGGGGAAGGTGTTC AGCTGCCAGCATCTTGCCTCCCACCCCCTCAGAAGGACAACATTCCAATGCTTTTGCTTTTACAAGAGCCTCATTTAACTACTCTTTTTG ATTTATTAGAGATGCTTGCATCATTTAAACCACCCTCAGGAAAAGTGGCAGTGGATGATAGTGAGAGCTTACGATGTGAAGAACTTCATC TTCATGCAGAAAATCTGTCTAGGCGGGTCTGGGAGCTACTGATGCTTCTTCCTACATGTCCTAATATGTTGATGGCATTCCAGAATATCT CAGATGAGCAGAGTAATGATGGATTTAATTGGAAAGAACTTCTCAAAATTAAGAGCGCCCACAAGCTATTGTATGCTCTGGAAATTATTG AAGCACTGGGAAAACCTAATAGAAGAATAAGGAGGGAGTCTACGGGAAGTTACAGTGATCTTTATCCAGATTCAGATGATTCAAGTGAAG ATCAAGTGGAAAATAGTAAAAATTCCTGGAGTTGCAAGTTTGTTGCTGCTGGAGGGCTTCAACAGTTATTAGAAATTTTTAATTCTGGAA TTCTAGAGCCTAAAGAGCAGGAATCATGGACTGTGTGGCAGCTAGACTGTCTTGCTTGCTTGCTGAAGTTAATATGCCAGTTTGCAGTAG ATCCATCCGATTTGGATTTAGCTTATCATGATGTCTTTGCCTGGTCTGGTATAGCGGAAAGCCATAGGAAAAGAACCTGGCCTGGCAAAT CAAGGAAGGCTGCTGGTGATCATGCTAAGGGTCTTCATATACCACGATTAACAGAGGTATTTCTTGTTCTTGTCCAAGGAACCAGTTTGA TTCAGCGACTTATGTCTGTTGCTTATACGTATGATAATCTGGCTCCTAGAGTTTTAAAAGCTCAGTCTGATCACAGGTCTAGACATGAAG TTTCACATTATTCAATGTGGCTCTTGGTGAGTTGGGCTCATTGCTGTTCTTTAGTGAAATCTAGCCTTGCTGATAGCGATCATTTACAAG ATTGGCTAAAGAAATTGACTCTCCTTATTCCTGAGACTGCAGTTCGTCATGAATCATGCAGTGGTCTCTATAAGTTATCCCTGTCAGGGC TGGATGGAGGAGACTCAATCAATCGTTCTTTTCTGCTATTGGCTGCCTCAACATTATTGAAATTTCTTCCTGATGCTCAAGCACTCAAAC CTATTAGGATAGATGATTATGAGGAAGAACCAATATTAAAACCAGGATGTAAAGAGTATTTTTGGTTGTTATGCAAATTAGTTGACAACA TACATATAAAGGACGCTAGTCAGACAACGCTCCTCGACTTAGATGCCTTGGCAAGACATTTGGCTGACTGTATTCGAAGTAGGGAGATCC TTGATCATCAGGATGGTAATGTAGAAGATGATGGGCTTACAGGACTCCTAAGGCTTGCAACAAGTGTTGTTAAACACAAACCACCCTTTA AATTTTCAAGGGAAGGACAGGAATTTTTGAGAGATATCTTCAATCTCCTGTTTTTGTTGCCAAGTCTAAAGGACCGACAACAGCCAAAGT GCAAATCACATTCTTCAAGAGCTGCCGCTTACGATTTGTTAGTAGAGATGGTAAAGGGGTCTGTTGAGAACTACAGGCTAATACACAACT GGGTTATGGCACAACACATGCAGTCCCATGCACCTTATAAATGGGATTACTGGCCTCATGAAGATGTCCGTGCTGAATGTAGATTTGTTG GCCTTACTAACCTTGGAGCTACTTGTTACTTAGCTTCTACTATTCAGCAACTTTATATGATACCTGAGGCAAGACAGGCTGTCTTCACTG CCAAGTATTCAGAGGATATGAAGCACAAGACCACTCTTCTGGAGCTTCAGAAAATGTTTACATATTTAATGAAAAATGCAAGAATGGCAG CAGAAAAGCATTATTCTAATACCCTAAAAGCACTAGGAATATCTGATGAGTTTGTTTCAAAGAAAGGCCAAAGTGGAAAAGTACTTGAGT ACTTCAACAATCAAGAGACGAAAAGTGTCACTGAAGACAAAGAAAGCTTTAATGAAGAAGAAAAAATAGAAGAAAGAGAGAATGGGGAAG AAAATTATTTTATTGATACCAACAGCCAGGATTCTTACAAGGAAAAAGATGAAGCCAATGAGGAAAGTGAAGAAGAGAAATCTGTTGAAG AATCACACTGAATCATCAAGGTCTCCTCTCTATGCCCTTGCTGTTGTTTGCAGCGTCAGGGTGTCAGCAGCCGCATTTGTGTTTAGAACA TCTGTGGGGACGCTTCTGATATGTGCAGGGCTGTTGATCAAAGTCATCTGTAGCCTGAAAAGCCTGAATCCAGCTGATTGGTCATTTGAT CAGTTAGAGTAAGGCTTTGCCTATTCAGTTTTAAAAATCATTGTGTATTATCTGTTTGCAACTATGATTTTGTATTTTTAAAAAGTGAGA ACCACAGCTGTCACAAACTGATTAGTTATAAAAATATACATTATTTCATTAATTTTACTGGAAAAAATGGCTTAGTATTGAAAGGAGAGA GAAGTATTGGTCTTTGGTGGTTTACTTTTTAAAAATTTTGGAAAGTGTGAATCAATAACTATTTTTAATTATACTATTTGCCCATTCTTT TTCTCTGCAGTGCATTTCACAGAATAAATCCTCTAACTTGTTTTGCTGCTCTGAGCCATTTTTAAAAGTATAGAAAAAACGCCGGGTATG GTGGCTCATGCCTGTAATCCCAGCATTTTGGGAGGCCGAGACGGGTGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGAT GAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGTGGGCGCCTGTAGTCCCAGCTACTTGGGAGGCAGAGGCAGGA GAATGGCATGAACCCAGGAGGCAGAGCTTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCTTGGGCAACAGAGCGAGACTCCGTCTC CAAAAAAAAAAAAAAAGTATAGAAAAAAATGGATACTTGCAAATTTACATTTATTTTTGCACTGAGAGTTTACTGTTAAATTGTCTACAC CATCATCCCTTTTTCTTTTTATCCTTAGTTCTAGTCCAAATTATTTTTGATTTGTAAATTATTAGGAAAGTTTTTATACTAGTTTTTTTA ACCCTATGTATTATTACAGATGGAAGTAATTATGGCATGTGTGAGTTATAATCTAAATTAGGGGCAAGTATCCCTTTTTTTATATGATGA AATTGTGCATAATAACTTGGCTAGGGCAAGTCTCCAAAGTAATTCAGATTTAACTCTTCACTGCTAGACCCAGTTGTGTTCAACTTTTTA CATATTATTGCCAACACACTTTATCTCTCTGTGTACAGTGTTAATCTGATTTTATAAATCTATATTTTTTTCTTTAAGCAAATTTTTGTT TTAAAATTTGAAGCCAATCATAAAGATAATATAGCATAAGACATTTTCTTTTCTAAAAACAATCAGCATCATTTTAAAAGGATGAACTAA TACAGGTGTATGTAATAGCAGTGTTTCCAAACTGGCAATTTATGCTTTAAATTTAAAAATAAGGTCATTTTTCTCCATCAGGGGCAAATG TTTACTTGTAATTTTCTTCCTACAGTTCGTGTTAAATTACTTTTTACTATTATTATATTGTAAACTCCTTGGGATTTGGCACCATTTAAA >97395_97395_1_USP34-FAM161A_USP34_chr2_61486846_ENST00000398571_FAM161A_chr2_62054393_ENST00000404929_length(amino acids)=2047AA_BP=1946 MCENCADLVEVLNEISDVEGGDGLQLRKEHTLKIFTYINSWTQRQCLCCFKEYKHLEIFNQVVCALINLVIAQVQVLRDQLCKHCTTINI DSTWQDESNQAEEPLNIDRECNEGSTERQKSIEKKSNSTRICNLTEEESSKSSDPFSLWSTDEKEKLLLCVAKIFQIQFPLYTAYKHNTH PTIEDISTQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHIIPFRT YVIRYLCKLSDQELRQSAARNMADLMWSTVKEPLDTTLCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETS IAKELADWLISNNVVEHIFGPNLHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKHCSRYIHDLFPSLIKNLDPVPLRHLLNLVSA LEPSVHTEQTLYLASMLIKALWNNALAAKAQLSKQSSFASLLNTNIPIGNKKEEEELRRTAPSPWSPAASPQSSDNSDTHQSGGSDIEMD EQLINRTKHVQQRLSDTEESMQGSSDETANSGEDGSSGPGSSSGHSDGSSNEVNSSHASQSAGSPGSEVQSEDIADIEALKEEDEDDDHG HNPPKSSCGTDLRNRKLESQAGICLGDSQGMSERNGTSSGTGKDLVFNTESLPSVDNRMRMLDACSHSEDPEHDISGEMNATHIAQGSQE SCITRTGDFLGETIGNELFNCRQFIGPQHHHHHHHHHHHHDGHMVDDMLSADDVSCSSSQVSAKSEKNMADFDGEESGCEEELVQINSHA ELTSHLQQHLPNLASIYHEHLSQGPVVHKHQFNSNAVTDINLDNVCKKGNTLLWDIVQDEDAVNLSEGLINEAEKLLCSLVCWFTDRQIR MRFIEGCLENLGNNRSVVISLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMKLFFDNLVYYIQTVREGRQKHALYSHSAEVQVRLQF LTCVFSTLGSPDHFRLSLEQVDILWHCLVEDSECYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHLCNLA RLATSAYDGCSNSELCGMDQFWGIALRAQSGDVSRAAIQYINSYYINGKTGLEKEQEFISKCMESLMIASSSLEQESHSSLMVIERGLLM LKTHLEAFRRRFAYHLRQWQIEGTGISSHLKALSDKQSLPLRVVCQPAGLPDKMTIEMYPSDQVADLRAEVTHWYENLQKEQINQQAQLQ EFGQSNRKGEFPGGLMGPVRMISSGHELTTDYDEKALHELGFKDMQMVFVSLGAPRRERKGEGVQLPASCLPPPQKDNIPMLLLLQEPHL TTLFDLLEMLASFKPPSGKVAVDDSESLRCEELHLHAENLSRRVWELLMLLPTCPNMLMAFQNISDEQSNDGFNWKELLKIKSAHKLLYA LEIIEALGKPNRRIRRESTGSYSDLYPDSDDSSEDQVENSKNSWSCKFVAAGGLQQLLEIFNSGILEPKEQESWTVWQLDCLACLLKLIC QFAVDPSDLDLAYHDVFAWSGIAESHRKRTWPGKSRKAAGDHAKGLHIPRLTEVFLVLVQGTSLIQRLMSVAYTYDNLAPRVLKAQSDHR SRHEVSHYSMWLLVSWAHCCSLVKSSLADSDHLQDWLKKLTLLIPETAVRHESCSGLYKLSLSGLDGGDSINRSFLLLAASTLLKFLPDA QALKPIRIDDYEEEPILKPGCKEYFWLLCKLVDNIHIKDASQTTLLDLDALARHLADCIRSREILDHQDGNVEDDGLTGLLRLATSVVKH KPPFKFSREGQEFLRDIFNLLFLLPSLKDRQQPKCKSHSSRAAAYDLLVEMVKGSVENYRLIHNWVMAQHMQSHAPYKWDYWPHEDVRAE CRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLLELQKMFTYLMKNARMAAEKHYSNTLKALGISDEFVSKKGQSG -------------------------------------------------------------- >97395_97395_2_USP34-FAM161A_USP34_chr2_61486846_ENST00000398571_FAM161A_chr2_62054393_ENST00000405894_length(transcript)=7820nt_BP=5921nt TCTCTCCCCTCCCCCCCGCCGGTCGGGATCAGTCAGTGTGATCCGAAGCGGGGGAGGGGGGGGGCGGCGGCCGAACGATGTGCGAGAACT GCGCAGACCTGGTGGAGGTGTTAAATGAAATATCAGATGTAGAAGGTGGTGATGGACTGCAGCTCAGAAAGGAACATACTCTCAAAATAT TTACTTATATCAATTCCTGGACACAGAGGCAATGTCTATGCTGCTTCAAGGAATATAAGCATTTGGAGATTTTTAATCAAGTAGTGTGTG CACTTATTAACTTAGTGATTGCCCAAGTTCAAGTGCTCCGGGACCAGCTTTGTAAACATTGTACTACCATTAACATAGATTCCACGTGGC AAGATGAGAGTAATCAAGCAGAAGAACCACTGAATATAGATAGAGAGTGTAATGAAGGAAGTACAGAAAGACAAAAATCAATAGAAAAAA AATCAAACTCTACAAGAATTTGTAATCTGACTGAGGAGGAATCTTCAAAGAGTTCTGATCCTTTTAGTTTATGGAGTACAGATGAGAAGG AAAAACTCTTACTATGTGTGGCAAAAATTTTTCAAATTCAGTTTCCCTTATATACTGCTTACAAGCATAATACTCACCCTACTATTGAGG ATATATCAACTCAAGAAAGTAACATATTAGGGGCATTCTGTGATATGAATGATGTAGAAGTACCATTGCATTTGCTTCGTTATGTATGTT TGTTTTGTGGGAAAAATGGCCTTTCTCTCATGAAGGATTGCTTTGAATATGGAACTCCTGAAACTTTGCCATTTCTTATAGCACATGCGT TTATTACAGTTGTGTCTAATATTAGAATATGGCTACATATTCCCGCTGTCATGCAGCACATTATACCTTTTAGGACCTATGTTATTAGGT ATTTATGCAAGCTCTCGGATCAGGAGTTACGACAGAGTGCAGCTCGTAACATGGCTGACTTAATGTGGAGCACAGTCAAAGAACCATTGG ATACAACATTATGCTTTGATAAAGAAAGCCTAGATCTTGCATTTAAGTACTTTATGTCACCTACTTTGACTATGAGGTTGGCTGGATTGA GTCAGATAACAAATCAACTCCATACCTTCAATGATGTGTGCAATAATGAATCATTAGTATCGGACACAGAAACGTCCATTGCAAAAGAAC TTGCAGACTGGCTTATTAGCAACAATGTGGTGGAGCATATATTTGGACCAAATTTACATATTGAGATTATCAAACAGTGCCAAGTGATTT TGAATTTTTTGGCAGCAGAAGGGCGACTGAGTACTCAACATATTGACTGTATTTGGGCTGCAGCACAGTTGAAACATTGTAGTCGGTATA TACATGACTTATTTCCTTCACTCATCAAGAATTTGGATCCCGTACCACTTAGACATCTACTTAATCTGGTCTCAGCTCTTGAGCCAAGTG TTCATACTGAACAGACACTGTACTTGGCATCCATGTTAATTAAAGCACTGTGGAATAACGCACTAGCAGCTAAGGCTCAGTTATCTAAAC AGAGTTCTTTTGCATCTTTATTAAATACTAATATTCCCATTGGAAATAAGAAAGAGGAAGAAGAGCTTAGAAGAACAGCTCCATCACCTT GGTCACCTGCAGCTAGTCCTCAAAGCAGTGATAATAGCGATACACATCAAAGTGGAGGTAGTGACATTGAAATGGATGAGCAACTTATTA ATAGAACCAAACATGTGCAACAACGACTTTCAGACACAGAGGAATCCATGCAGGGAAGTTCTGACGAAACTGCCAACAGTGGTGAAGATG GAAGCAGTGGTCCTGGTAGCAGTAGTGGGCATAGTGATGGATCTAGCAATGAGGTTAATTCTAGCCACGCAAGCCAGTCAGCTGGGAGCC CTGGCAGTGAGGTACAGTCAGAAGACATTGCAGATATTGAAGCCCTCAAAGAGGAAGATGAAGACGATGATCATGGTCATAATCCTCCCA AAAGCAGTTGTGGTACAGATCTTCGGAATAGAAAGTTAGAGAGTCAAGCAGGCATTTGCCTGGGGGACTCCCAAGGCATGTCAGAAAGAA ATGGGACAAGCAGCGGAACAGGAAAGGACCTGGTTTTTAACACTGAATCATTGCCATCAGTAGATAATCGAATGCGAATGCTGGATGCTT GTTCACACTCTGAAGACCCAGAACATGATATTTCAGGGGAAATGAATGCTACTCATATAGCACAAGGGTCTCAGGAGTCTTGTATCACAC GAACTGGGGACTTCCTTGGGGAGACTATTGGGAATGAATTATTTAATTGTCGACAATTTATTGGTCCACAGCATCACCACCACCACCACC ACCATCACCACCACCACGATGGGCATATGGTTGATGATATGCTAAGTGCAGATGATGTCAGTTGTAGTAGCTCCCAGGTTAGTGCAAAAT CAGAAAAAAATATGGCTGATTTTGATGGTGAAGAATCTGGATGTGAAGAGGAGCTAGTTCAGATTAATTCACATGCGGAACTGACATCTC ACCTCCAACAACATCTTCCCAATTTAGCTTCCATTTACCATGAACATCTTAGTCAAGGACCTGTAGTTCATAAACATCAATTCAACAGTA ATGCTGTTACAGACATTAATTTGGATAATGTTTGCAAGAAAGGAAATACTTTGTTGTGGGATATAGTCCAAGATGAAGATGCAGTTAATC TTTCTGAAGGATTAATAAATGAAGCAGAGAAACTTCTTTGTTCGTTAGTATGTTGGTTTACAGATAGACAAATTCGAATGAGATTCATTG AAGGTTGCCTTGAAAACTTGGGAAACAACAGATCAGTAGTAATTTCACTTCGTCTTCTTCCAAAACTATTTGGTACTTTTCAGCAGTTTG GGAGCAGTTACGATACACACTGGATAACAATGTGGGCAGAAAAAGAACTGAACATGATGAAGCTTTTCTTTGATAATTTGGTATACTACA TTCAAACTGTGAGAGAAGGAAGACAAAAACATGCACTGTACAGCCATAGTGCTGAAGTTCAAGTTCGTCTTCAATTCTTGACTTGTGTAT TTTCAACTCTGGGATCACCTGATCATTTCAGGTTAAGTTTAGAGCAAGTTGACATCTTATGGCATTGTTTAGTAGAAGATTCTGAATGTT ATGATGATGCACTCCATTGGTTTTTAAATCAAGTTCGAAGTAAAGATCAACATGCTATGGGTATGGAAACCTACAAACATCTTTTCCTGG AGAAGATGCCCCAGCTAAAACCTGAAACAATTAGCATGACTGGCTTAAACCTGTTTCAGCATCTCTGTAACTTGGCTCGATTGGCTACCA GTGCCTATGATGGTTGTTCAAATTCTGAGCTGTGTGGTATGGACCAATTTTGGGGCATTGCTTTAAGAGCACAATCTGGTGATGTCAGTC GAGCAGCTATCCAGTATATTAACTCCTATTATATTAATGGTAAAACAGGTTTGGAGAAGGAGCAAGAATTTATTAGTAAGTGCATGGAGA GTCTTATGATAGCTTCTAGCAGTCTTGAACAGGAATCACACTCAAGTCTCATGGTTATAGAAAGAGGACTCCTTATGCTGAAGACACATC TGGAAGCGTTTAGGAGAAGGTTTGCATATCATCTGAGACAGTGGCAAATTGAAGGCACTGGTATTAGTAGTCATTTGAAAGCACTGAGTG ACAAACAGTCTCTGCCGCTAAGGGTTGTATGCCAGCCAGCTGGACTTCCTGACAAGATGACTATTGAAATGTATCCTAGTGACCAGGTAG CAGATCTTAGGGCTGAAGTAACTCATTGGTATGAAAATTTACAGAAAGAACAAATAAATCAACAAGCTCAGCTTCAGGAGTTTGGTCAAA GCAACCGAAAAGGAGAGTTTCCTGGAGGCCTCATGGGACCTGTCAGGATGATTTCATCTGGACACGAGTTAACAACAGATTATGATGAAA AAGCACTTCATGAGCTTGGTTTTAAGGATATGCAGATGGTATTTGTATCTTTGGGTGCACCAAGGAGAGAGCGGAAAGGGGAAGGTGTTC AGCTGCCAGCATCTTGCCTCCCACCCCCTCAGAAGGACAACATTCCAATGCTTTTGCTTTTACAAGAGCCTCATTTAACTACTCTTTTTG ATTTATTAGAGATGCTTGCATCATTTAAACCACCCTCAGGAAAAGTGGCAGTGGATGATAGTGAGAGCTTACGATGTGAAGAACTTCATC TTCATGCAGAAAATCTGTCTAGGCGGGTCTGGGAGCTACTGATGCTTCTTCCTACATGTCCTAATATGTTGATGGCATTCCAGAATATCT CAGATGAGCAGAGTAATGATGGATTTAATTGGAAAGAACTTCTCAAAATTAAGAGCGCCCACAAGCTATTGTATGCTCTGGAAATTATTG AAGCACTGGGAAAACCTAATAGAAGAATAAGGAGGGAGTCTACGGGAAGTTACAGTGATCTTTATCCAGATTCAGATGATTCAAGTGAAG ATCAAGTGGAAAATAGTAAAAATTCCTGGAGTTGCAAGTTTGTTGCTGCTGGAGGGCTTCAACAGTTATTAGAAATTTTTAATTCTGGAA TTCTAGAGCCTAAAGAGCAGGAATCATGGACTGTGTGGCAGCTAGACTGTCTTGCTTGCTTGCTGAAGTTAATATGCCAGTTTGCAGTAG ATCCATCCGATTTGGATTTAGCTTATCATGATGTCTTTGCCTGGTCTGGTATAGCGGAAAGCCATAGGAAAAGAACCTGGCCTGGCAAAT CAAGGAAGGCTGCTGGTGATCATGCTAAGGGTCTTCATATACCACGATTAACAGAGGTATTTCTTGTTCTTGTCCAAGGAACCAGTTTGA TTCAGCGACTTATGTCTGTTGCTTATACGTATGATAATCTGGCTCCTAGAGTTTTAAAAGCTCAGTCTGATCACAGGTCTAGACATGAAG TTTCACATTATTCAATGTGGCTCTTGGTGAGTTGGGCTCATTGCTGTTCTTTAGTGAAATCTAGCCTTGCTGATAGCGATCATTTACAAG ATTGGCTAAAGAAATTGACTCTCCTTATTCCTGAGACTGCAGTTCGTCATGAATCATGCAGTGGTCTCTATAAGTTATCCCTGTCAGGGC TGGATGGAGGAGACTCAATCAATCGTTCTTTTCTGCTATTGGCTGCCTCAACATTATTGAAATTTCTTCCTGATGCTCAAGCACTCAAAC CTATTAGGATAGATGATTATGAGGAAGAACCAATATTAAAACCAGGATGTAAAGAGTATTTTTGGTTGTTATGCAAATTAGTTGACAACA TACATATAAAGGACGCTAGTCAGACAACGCTCCTCGACTTAGATGCCTTGGCAAGACATTTGGCTGACTGTATTCGAAGTAGGGAGATCC TTGATCATCAGGATGGTAATGTAGAAGATGATGGGCTTACAGGACTCCTAAGGCTTGCAACAAGTGTTGTTAAACACAAACCACCCTTTA AATTTTCAAGGGAAGGACAGGAATTTTTGAGAGATATCTTCAATCTCCTGTTTTTGTTGCCAAGTCTAAAGGACCGACAACAGCCAAAGT GCAAATCACATTCTTCAAGAGCTGCCGCTTACGATTTGTTAGTAGAGATGGTAAAGGGGTCTGTTGAGAACTACAGGCTAATACACAACT GGGTTATGGCACAACACATGCAGTCCCATGCACCTTATAAATGGGATTACTGGCCTCATGAAGATGTCCGTGCTGAATGTAGATTTGTTG GCCTTACTAACCTTGGAGCTACTTGTTACTTAGCTTCTACTATTCAGCAACTTTATATGATACCTGAGGCAAGACAGGCTGTCTTCACTG CCAAGTATTCAGAGGATATGAAGCACAAGACCACTCTTCTGGAGCTTCAGAAAATGTTTACATATTTAATGAAAAATGCAAGAATGGCAG CAGAAAAGCATTATTCTAATACCCTAAAAGCACTAGGAATATCTGATGAGTTTGTTTCAAAGAAAGGCCAAAGTGGAAAAGTACTTGAGT ACTTCAACAATCAAGAGACGAAAAGTGTCACTGAAGACAAAGAAAGCTTTAATGAAGAAGAAAAAATAGAAGAAAGAGAGAATGGGGAAG AAAATTATTTTATTGATACCAACAGCCAGGATTCTTACAAGGAAAAAGATGAAGCCAATGAGGAAAGTGAAGAAGAGAAATCTGTTGAAG AATCACACTGAATCATCAAGGTCTCCTCTCTATGCCCTTGCTGTTGTTTGCAGCGTCAGGGTGTCAGCAGCCGCATTTGTGTTTAGAACA TCTGTGGGGACGCTTCTGATATGTGCAGGGCTGTTGATCAAAGTCATCTGTAGCCTGAAAAGCCTGAATCCAGCTGATTGGTCATTTGAT CAGTTAGAGTAAGGCTTTGCCTATTCAGTTTTAAAAATCATTGTGTATTATCTGTTTGCAACTATGATTTTGTATTTTTAAAAAGTGAGA ACCACAGCTGTCACAAACTGATTAGTTATAAAAATATACATTATTTCATTAATTTTACTGGAAAAAATGGCTTAGTATTGAAAGGAGAGA GAAGTATTGGTCTTTGGTGGTTTACTTTTTAAAAATTTTGGAAAGTGTGAATCAATAACTATTTTTAATTATACTATTTGCCCATTCTTT TTCTCTGCAGTGCATTTCACAGAATAAATCCTCTAACTTGTTTTGCTGCTCTGAGCCATTTTTAAAAGTATAGAAAAAACGCCGGGTATG GTGGCTCATGCCTGTAATCCCAGCATTTTGGGAGGCCGAGACGGGTGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGAT GAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGTGGGCGCCTGTAGTCCCAGCTACTTGGGAGGCAGAGGCAGGA GAATGGCATGAACCCAGGAGGCAGAGCTTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCTTGGGCAACAGAGCGAGACTCCGTCTC CAAAAAAAAAAAAAAAGTATAGAAAAAAATGGATACTTGCAAATTTACATTTATTTTTGCACTGAGAGTTTACTGTTAAATTGTCTACAC CATCATCCCTTTTTCTTTTTATCCTTAGTTCTAGTCCAAATTATTTTTGATTTGTAAATTATTAGGAAAGTTTTTATACTAGTTTTTTTA ACCCTATGTATTATTACAGATGGAAGTAATTATGGCATGTGTGAGTTATAATCTAAATTAGGGGCAAGTATCCCTTTTTTTATATGATGA AATTGTGCATAATAACTTGGCTAGGGCAAGTCTCCAAAGTAATTCAGATTTAACTCTTCACTGCTAGACCCAGTTGTGTTCAACTTTTTA CATATTATTGCCAACACACTTTATCTCTCTGTGTACAGTGTTAATCTGATTTTATAAATCTATATTTTTTTCTTTAAGCAAATTTTTGTT TTAAAATTTGAAGCCAATCATAAAGATAATATAGCATAAGACATTTTCTTTTCTAAAAACAATCAGCATCATTTTAAAAGGATGAACTAA TACAGGTGTATGTAATAGCAGTGTTTCCAAACTGGCAATTTATGCTTTAAATTTAAAAATAAGGTCATTTTTCTCCATCAGGGGCAAATG TTTACTTGTAATTTTCTTCCTACAGTTCGTGTTAAATTACTTTTTACTATTATTATATTGTAAACTCCTTGGGATTTGGCACCATTTAAA >97395_97395_2_USP34-FAM161A_USP34_chr2_61486846_ENST00000398571_FAM161A_chr2_62054393_ENST00000405894_length(amino acids)=2047AA_BP=1946 MCENCADLVEVLNEISDVEGGDGLQLRKEHTLKIFTYINSWTQRQCLCCFKEYKHLEIFNQVVCALINLVIAQVQVLRDQLCKHCTTINI DSTWQDESNQAEEPLNIDRECNEGSTERQKSIEKKSNSTRICNLTEEESSKSSDPFSLWSTDEKEKLLLCVAKIFQIQFPLYTAYKHNTH PTIEDISTQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHIIPFRT YVIRYLCKLSDQELRQSAARNMADLMWSTVKEPLDTTLCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETS IAKELADWLISNNVVEHIFGPNLHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKHCSRYIHDLFPSLIKNLDPVPLRHLLNLVSA LEPSVHTEQTLYLASMLIKALWNNALAAKAQLSKQSSFASLLNTNIPIGNKKEEEELRRTAPSPWSPAASPQSSDNSDTHQSGGSDIEMD EQLINRTKHVQQRLSDTEESMQGSSDETANSGEDGSSGPGSSSGHSDGSSNEVNSSHASQSAGSPGSEVQSEDIADIEALKEEDEDDDHG HNPPKSSCGTDLRNRKLESQAGICLGDSQGMSERNGTSSGTGKDLVFNTESLPSVDNRMRMLDACSHSEDPEHDISGEMNATHIAQGSQE SCITRTGDFLGETIGNELFNCRQFIGPQHHHHHHHHHHHHDGHMVDDMLSADDVSCSSSQVSAKSEKNMADFDGEESGCEEELVQINSHA ELTSHLQQHLPNLASIYHEHLSQGPVVHKHQFNSNAVTDINLDNVCKKGNTLLWDIVQDEDAVNLSEGLINEAEKLLCSLVCWFTDRQIR MRFIEGCLENLGNNRSVVISLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMKLFFDNLVYYIQTVREGRQKHALYSHSAEVQVRLQF LTCVFSTLGSPDHFRLSLEQVDILWHCLVEDSECYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHLCNLA RLATSAYDGCSNSELCGMDQFWGIALRAQSGDVSRAAIQYINSYYINGKTGLEKEQEFISKCMESLMIASSSLEQESHSSLMVIERGLLM LKTHLEAFRRRFAYHLRQWQIEGTGISSHLKALSDKQSLPLRVVCQPAGLPDKMTIEMYPSDQVADLRAEVTHWYENLQKEQINQQAQLQ EFGQSNRKGEFPGGLMGPVRMISSGHELTTDYDEKALHELGFKDMQMVFVSLGAPRRERKGEGVQLPASCLPPPQKDNIPMLLLLQEPHL TTLFDLLEMLASFKPPSGKVAVDDSESLRCEELHLHAENLSRRVWELLMLLPTCPNMLMAFQNISDEQSNDGFNWKELLKIKSAHKLLYA LEIIEALGKPNRRIRRESTGSYSDLYPDSDDSSEDQVENSKNSWSCKFVAAGGLQQLLEIFNSGILEPKEQESWTVWQLDCLACLLKLIC QFAVDPSDLDLAYHDVFAWSGIAESHRKRTWPGKSRKAAGDHAKGLHIPRLTEVFLVLVQGTSLIQRLMSVAYTYDNLAPRVLKAQSDHR SRHEVSHYSMWLLVSWAHCCSLVKSSLADSDHLQDWLKKLTLLIPETAVRHESCSGLYKLSLSGLDGGDSINRSFLLLAASTLLKFLPDA QALKPIRIDDYEEEPILKPGCKEYFWLLCKLVDNIHIKDASQTTLLDLDALARHLADCIRSREILDHQDGNVEDDGLTGLLRLATSVVKH KPPFKFSREGQEFLRDIFNLLFLLPSLKDRQQPKCKSHSSRAAAYDLLVEMVKGSVENYRLIHNWVMAQHMQSHAPYKWDYWPHEDVRAE CRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLLELQKMFTYLMKNARMAAEKHYSNTLKALGISDEFVSKKGQSG -------------------------------------------------------------- >97395_97395_3_USP34-FAM161A_USP34_chr2_61597456_ENST00000398571_FAM161A_chr2_62069495_ENST00000404929_length(transcript)=4895nt_BP=1328nt TCTCTCCCCTCCCCCCCGCCGGTCGGGATCAGTCAGTGTGATCCGAAGCGGGGGAGGGGGGGGGCGGCGGCCGAACGATGTGCGAGAACT GCGCAGACCTGGTGGAGGTGTTAAATGAAATATCAGATGTAGAAGGTGGTGATGGACTGCAGCTCAGAAAGGAACATACTCTCAAAATAT TTACTTATATCAATTCCTGGACACAGAGGCAATGTCTATGCTGCTTCAAGGAATATAAGCATTTGGAGATTTTTAATCAAGTAGTGTGTG CACTTATTAACTTAGTGATTGCCCAAGTTCAAGTGCTCCGGGACCAGCTTTGTAAACATTGTACTACCATTAACATAGATTCCACGTGGC AAGATGAGAGTAATCAAGCAGAAGAACCACTGAATATAGATAGAGAGTGTAATGAAGGAAGTACAGAAAGACAAAAATCAATAGAAAAAA AATCAAACTCTACAAGAATTTGTAATCTGACTGAGGAGGAATCTTCAAAGAGTTCTGATCCTTTTAGTTTATGGAGTACAGATGAGAAGG AAAAACTCTTACTATGTGTGGCAAAAATTTTTCAAATTCAGTTTCCCTTATATACTGCTTACAAGCATAATACTCACCCTACTATTGAGG ATATATCAACTCAAGAAAGTAACATATTAGGGGCATTCTGTGATATGAATGATGTAGAAGTACCATTGCATTTGCTTCGTTATGTATGTT TGTTTTGTGGGAAAAATGGCCTTTCTCTCATGAAGGATTGCTTTGAATATGGAACTCCTGAAACTTTGCCATTTCTTATAGCACATGCGT TTATTACAGTTGTGTCTAATATTAGAATATGGCTACATATTCCCGCTGTCATGCAGCACATTATACCTTTTAGGACCTATGTTATTAGGT ATTTATGCAAGCTCTCGGATCAGGAGTTACGACAGAGTGCAGCTCGTAACATGGCTGACTTAATGTGGAGCACAGTCAAAGAACCATTGG ATACAACATTATGCTTTGATAAAGAAAGCCTAGATCTTGCATTTAAGTACTTTATGTCACCTACTTTGACTATGAGGTTGGCTGGATTGA GTCAGATAACAAATCAACTCCATACCTTCAATGATGTGTGCAATAATGAATCATTAGTATCGGACACAGAAACGTCCATTGCAAAAGAAC TTGCAGACTGGCTTATTAGCAACAATGTGGTGGAGCATATATTTGGACCAAATTTACATATTGAGATTATCAAACAGTGCCAAGTGATTT TGAATTTTTTGGCAGCAGAAGGGCGACTGAGTACTCAACATATTGACTGTATTTGGGCTGCAGCACAGGCTGATTTGAACACCAGCTTTT CTGGGGTGGATGAACATGCACCGATAAGCTATGAGGACTTTGTGAACTTTCCTGATATTCACCACTCTAATGAGGAGTATTTCAAGAAAG TAGAAGAGTTGAAGGCTGCCCACATAGAAACTATGGCAAAATTAGAGAAAATGTACCAGGATAAATTACATTTAAAGGAAGTTCAGCCAG TGGTCATCAGAGAAGACTCTCTTAGTGACTCTTCCAGATCTGTATCAGAAAAGAACTCCTATCACCCTGTCTCATTAATGACATCATTTT CAGAGCCTGATTTAGGCCAGTCTTCCTCCTTGTATGTGTCCTCCTCTGAAGAGGAGTTACCCAACCTAGAAAAAGAGTATCCTAGGAAAA ACAGAATGATGACCTATGCTAAGGAGCTCATCAACAATATGTGGACAGACTTTTGTGTTGAGGATTATATTCGCTGTAAAGATACTGGCT TCCATGCAGCTGAAAAAAGAAGGAAGAAACGAAAAGAATGGGTGCCCACAATTACAGTACCGGAGCCTTTTCAAATGATGATAAGAGAAC AGAAGAAAAAAGAAGAGTCCATGAAATCTAAATCAGATATCGAAATGGTACATAAAGCGCTCAAAAAACAAGAAGAGGATCCAGAGTATA AGAAGAAATTCCGAGCCAATCCAGTTCCTGCATCTGTCTTTCTCCCCCTTTACCATGATTTAGTCAAGCAAAAAGAAGAACGGAGAAGGT CTCTGAAGGAGAAAAGCAAAGAAGCTCTTTTGGCCTCACAAAAGCCATTTAAATTTATAGCAAGGGAGGAACAGAAGCGAGCAGCCCGGG AAAAGCAGCTGAGAGACTTTCTTAAGTATAAAAAGAAAACAAATCGATTTAAAGCCAGACCCATTCCTCGATCTACTTATGGTTCAACTA CCAATGACAAGTTAAAAGAAGAAGAGCTCTATCGAAACCTTAGGACACAGCTGAGAGCCCAGGAGCATTTACAGAACTCATCTCCTCTGC CTTGTAGGTCAGCTTGTGGATGCAGGAACCCCAGGTGTCCTGAACAGGCTGTAAAGTTGAAGTGTAAACACAAGGTTAGGTGCCCAACTC CTGATTTTGAGGACCTTCCTGAGAGATACCAGAAACACCTCTCAGAACACAAGTCTCCAAAACTCTTAACAGTGTGTAAACCATTTGATC TTCATGCATCTCCACATGCATCTATTAAAAGAGAAAAAATTTTGGCAGACATCGAAGCAGATGAAGAAAATTTAAAAGAAACACGTTGGC CTTATTTGTCTCCAAGGCGTAAGTCACCAGTAAGATGTGCAGGTGTAAACCCTGTGCCTTGTAACTGCAACCCTCCCGTGCCCACGGTAT CTTCCAGAGGACGAGAACAAGCCGTAAGGAGATCACTTGAGGAAAAGAAAATGTTGGAAGAAGAGAGAAATCGGATCCTAACTAAACAGA AGCAAAGAATGAAAGAATTGCAGAAACTCCTGACAACCCGGGCTAAGGCTTATGACTCACATCAAAGTTTAGCTCAAATATCTAAATCCA GAGTAAAATGTCTCAGAAAGAGCGAAAAGGAAAGGATGAGAGAATACCAACGAGAACTAGAAGAAAGAGAAGAAAAATTAAAAAAGAGGC CACTGCTATTTGAAAGAGTTGCTCAGAAAAATGCAAGAATGGCAGCAGAAAAGCATTATTCTAATACCCTAAAAGCACTAGGAATATCTG ATGAGTTTGTTTCAAAGAAAGGCCAAAGTGGAAAAGTACTTGAGTACTTCAACAATCAAGAGACGAAAAGTGTCACTGAAGACAAAGAAA GCTTTAATGAAGAAGAAAAAATAGAAGAAAGAGAGAATGGGGAAGAAAATTATTTTATTGATACCAACAGCCAGGATTCTTACAAGGAAA AAGATGAAGCCAATGAGGAAAGTGAAGAAGAGAAATCTGTTGAAGAATCACACTGAATCATCAAGGTCTCCTCTCTATGCCCTTGCTGTT GTTTGCAGCGTCAGGGTGTCAGCAGCCGCATTTGTGTTTAGAACATCTGTGGGGACGCTTCTGATATGTGCAGGGCTGTTGATCAAAGTC ATCTGTAGCCTGAAAAGCCTGAATCCAGCTGATTGGTCATTTGATCAGTTAGAGTAAGGCTTTGCCTATTCAGTTTTAAAAATCATTGTG TATTATCTGTTTGCAACTATGATTTTGTATTTTTAAAAAGTGAGAACCACAGCTGTCACAAACTGATTAGTTATAAAAATATACATTATT TCATTAATTTTACTGGAAAAAATGGCTTAGTATTGAAAGGAGAGAGAAGTATTGGTCTTTGGTGGTTTACTTTTTAAAAATTTTGGAAAG TGTGAATCAATAACTATTTTTAATTATACTATTTGCCCATTCTTTTTCTCTGCAGTGCATTTCACAGAATAAATCCTCTAACTTGTTTTG CTGCTCTGAGCCATTTTTAAAAGTATAGAAAAAACGCCGGGTATGGTGGCTCATGCCTGTAATCCCAGCATTTTGGGAGGCCGAGACGGG TGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGATGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCAGGCGTGG TGGTGGGCGCCTGTAGTCCCAGCTACTTGGGAGGCAGAGGCAGGAGAATGGCATGAACCCAGGAGGCAGAGCTTGCAGTGAGCCGAGATC GCGCCACTGCACTCCAGCTTGGGCAACAGAGCGAGACTCCGTCTCCAAAAAAAAAAAAAAAGTATAGAAAAAAATGGATACTTGCAAATT TACATTTATTTTTGCACTGAGAGTTTACTGTTAAATTGTCTACACCATCATCCCTTTTTCTTTTTATCCTTAGTTCTAGTCCAAATTATT TTTGATTTGTAAATTATTAGGAAAGTTTTTATACTAGTTTTTTTAACCCTATGTATTATTACAGATGGAAGTAATTATGGCATGTGTGAG TTATAATCTAAATTAGGGGCAAGTATCCCTTTTTTTATATGATGAAATTGTGCATAATAACTTGGCTAGGGCAAGTCTCCAAAGTAATTC AGATTTAACTCTTCACTGCTAGACCCAGTTGTGTTCAACTTTTTACATATTATTGCCAACACACTTTATCTCTCTGTGTACAGTGTTAAT CTGATTTTATAAATCTATATTTTTTTCTTTAAGCAAATTTTTGTTTTAAAATTTGAAGCCAATCATAAAGATAATATAGCATAAGACATT TTCTTTTCTAAAAACAATCAGCATCATTTTAAAAGGATGAACTAATACAGGTGTATGTAATAGCAGTGTTTCCAAACTGGCAATTTATGC TTTAAATTTAAAAATAAGGTCATTTTTCTCCATCAGGGGCAAATGTTTACTTGTAATTTTCTTCCTACAGTTCGTGTTAAATTACTTTTT ACTATTATTATATTGTAAACTCCTTGGGATTTGGCACCATTTAAAAATTCATCTTTGTATTCCCTTAATATTTGGAACAGTATTGTACAT >97395_97395_3_USP34-FAM161A_USP34_chr2_61597456_ENST00000398571_FAM161A_chr2_62069495_ENST00000404929_length(amino acids)=1072AA_BP=416 MCENCADLVEVLNEISDVEGGDGLQLRKEHTLKIFTYINSWTQRQCLCCFKEYKHLEIFNQVVCALINLVIAQVQVLRDQLCKHCTTINI DSTWQDESNQAEEPLNIDRECNEGSTERQKSIEKKSNSTRICNLTEEESSKSSDPFSLWSTDEKEKLLLCVAKIFQIQFPLYTAYKHNTH PTIEDISTQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHIIPFRT YVIRYLCKLSDQELRQSAARNMADLMWSTVKEPLDTTLCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETS IAKELADWLISNNVVEHIFGPNLHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQADLNTSFSGVDEHAPISYEDFVNFPDIHHSNEE YFKKVEELKAAHIETMAKLEKMYQDKLHLKEVQPVVIREDSLSDSSRSVSEKNSYHPVSLMTSFSEPDLGQSSSLYVSSSEEELPNLEKE YPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKKQEE DPEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFKARPIPRST YGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVC KPFDLHASPHASIKREKILADIEADEENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRRSLEEKKMLEEERNRI LTKQKQRMKELQKLLTTRAKAYDSHQSLAQISKSRVKCLRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKA -------------------------------------------------------------- >97395_97395_4_USP34-FAM161A_USP34_chr2_61597456_ENST00000398571_FAM161A_chr2_62069495_ENST00000405894_length(transcript)=4727nt_BP=1328nt TCTCTCCCCTCCCCCCCGCCGGTCGGGATCAGTCAGTGTGATCCGAAGCGGGGGAGGGGGGGGGCGGCGGCCGAACGATGTGCGAGAACT GCGCAGACCTGGTGGAGGTGTTAAATGAAATATCAGATGTAGAAGGTGGTGATGGACTGCAGCTCAGAAAGGAACATACTCTCAAAATAT TTACTTATATCAATTCCTGGACACAGAGGCAATGTCTATGCTGCTTCAAGGAATATAAGCATTTGGAGATTTTTAATCAAGTAGTGTGTG CACTTATTAACTTAGTGATTGCCCAAGTTCAAGTGCTCCGGGACCAGCTTTGTAAACATTGTACTACCATTAACATAGATTCCACGTGGC AAGATGAGAGTAATCAAGCAGAAGAACCACTGAATATAGATAGAGAGTGTAATGAAGGAAGTACAGAAAGACAAAAATCAATAGAAAAAA AATCAAACTCTACAAGAATTTGTAATCTGACTGAGGAGGAATCTTCAAAGAGTTCTGATCCTTTTAGTTTATGGAGTACAGATGAGAAGG AAAAACTCTTACTATGTGTGGCAAAAATTTTTCAAATTCAGTTTCCCTTATATACTGCTTACAAGCATAATACTCACCCTACTATTGAGG ATATATCAACTCAAGAAAGTAACATATTAGGGGCATTCTGTGATATGAATGATGTAGAAGTACCATTGCATTTGCTTCGTTATGTATGTT TGTTTTGTGGGAAAAATGGCCTTTCTCTCATGAAGGATTGCTTTGAATATGGAACTCCTGAAACTTTGCCATTTCTTATAGCACATGCGT TTATTACAGTTGTGTCTAATATTAGAATATGGCTACATATTCCCGCTGTCATGCAGCACATTATACCTTTTAGGACCTATGTTATTAGGT ATTTATGCAAGCTCTCGGATCAGGAGTTACGACAGAGTGCAGCTCGTAACATGGCTGACTTAATGTGGAGCACAGTCAAAGAACCATTGG ATACAACATTATGCTTTGATAAAGAAAGCCTAGATCTTGCATTTAAGTACTTTATGTCACCTACTTTGACTATGAGGTTGGCTGGATTGA GTCAGATAACAAATCAACTCCATACCTTCAATGATGTGTGCAATAATGAATCATTAGTATCGGACACAGAAACGTCCATTGCAAAAGAAC TTGCAGACTGGCTTATTAGCAACAATGTGGTGGAGCATATATTTGGACCAAATTTACATATTGAGATTATCAAACAGTGCCAAGTGATTT TGAATTTTTTGGCAGCAGAAGGGCGACTGAGTACTCAACATATTGACTGTATTTGGGCTGCAGCACAGGCTGATTTGAACACCAGCTTTT CTGGGGTGGATGAACATGCACCGATAAGCTATGAGGACTTTGTGAACTTTCCTGATATTCACCACTCTAATGAGGAGTATTTCAAGAAAG TAGAAGAGTTGAAGGCTGCCCACATAGAAACTATGGCAAAATTAGAGAAAATGTACCAGGATAAATTACATTTAAAGGAAGTTCAGCCAG TGGTCATCAGAGAAGACTCTCTTAGTGACTCTTCCAGATCTGTATCAGAAAAGAACTCCTATCACCCTGTCTCATTAATGACATCATTTT CAGAGCCTGATTTAGGCCAGTCTTCCTCCTTGTATGTGTCCTCCTCTGAAGAGGAGTTACCCAACCTAGAAAAAGAGTATCCTAGGAAAA ACAGAATGATGACCTATGCTAAGGAGCTCATCAACAATATGTGGACAGACTTTTGTGTTGAGGATTATATTCGCTGTAAAGATACTGGCT TCCATGCAGCTGAAAAAAGAAGGAAGAAACGAAAAGAATGGGTGCCCACAATTACAGTACCGGAGCCTTTTCAAATGATGATAAGAGAAC AGAAGAAAAAAGAAGAGTCCATGAAATCTAAATCAGATATCGAAATGGTACATAAAGCGCTCAAAAAACAAGAAGAGGATCCAGAGTATA AGAAGAAATTCCGAGCCAATCCAGTTCCTGCATCTGTCTTTCTCCCCCTTTACCATGATTTAGTCAAGCAAAAAGAAGAACGGAGAAGGT CTCTGAAGGAGAAAAGCAAAGAAGCTCTTTTGGCCTCACAAAAGCCATTTAAATTTATAGCAAGGGAGGAACAGAAGCGAGCAGCCCGGG AAAAGCAGCTGAGAGACTTTCTTAAGTATAAAAAGAAAACAAATCGATTTAAAGCCAGACCCATTCCTCGATCTACTTATGGTTCAACTA CCAATGACAAGTTAAAAGAAGAAGAGCTCTATCGAAACCTTAGGACACAGCTGAGAGCCCAGGAGCATTTACAGAACTCATCTCCTCTGC CTTGTAGGTCAGCTTGTGGATGCAGGAACCCCAGGTGTCCTGAACAGGCTGTAAAGTTGAAGTGTAAACACAAGGTTAGGTGCCCAACTC CTGATTTTGAGGACCTTCCTGAGAGATACCAGAAACACCTCTCAGAACACAAGTCTCCAAAACTCTTAACAGTGTGTAAACCATTTGATC TTCATGCATCTCCACATGCATCTATTAAAAGAGAAAAAATTTTGGCAGACATCGAAGCAGATGAAGAAAATTTAAAAGAAACACGTTGGC CTTATTTGTCTCCAAGGCGTAAGTCACCAGTAAGATGTGCAGGTGTAAACCCTGTGCCTTGTAACTGCAACCCTCCCGTGCCCACGGTAT CTTCCAGAGGACGAGAACAAGCCGTAAGAAAGAGCGAAAAGGAAAGGATGAGAGAATACCAACGAGAACTAGAAGAAAGAGAAGAAAAAT TAAAAAAGAGGCCACTGCTATTTGAAAGAGTTGCTCAGAAAAATGCAAGAATGGCAGCAGAAAAGCATTATTCTAATACCCTAAAAGCAC TAGGAATATCTGATGAGTTTGTTTCAAAGAAAGGCCAAAGTGGAAAAGTACTTGAGTACTTCAACAATCAAGAGACGAAAAGTGTCACTG AAGACAAAGAAAGCTTTAATGAAGAAGAAAAAATAGAAGAAAGAGAGAATGGGGAAGAAAATTATTTTATTGATACCAACAGCCAGGATT CTTACAAGGAAAAAGATGAAGCCAATGAGGAAAGTGAAGAAGAGAAATCTGTTGAAGAATCACACTGAATCATCAAGGTCTCCTCTCTAT GCCCTTGCTGTTGTTTGCAGCGTCAGGGTGTCAGCAGCCGCATTTGTGTTTAGAACATCTGTGGGGACGCTTCTGATATGTGCAGGGCTG TTGATCAAAGTCATCTGTAGCCTGAAAAGCCTGAATCCAGCTGATTGGTCATTTGATCAGTTAGAGTAAGGCTTTGCCTATTCAGTTTTA AAAATCATTGTGTATTATCTGTTTGCAACTATGATTTTGTATTTTTAAAAAGTGAGAACCACAGCTGTCACAAACTGATTAGTTATAAAA ATATACATTATTTCATTAATTTTACTGGAAAAAATGGCTTAGTATTGAAAGGAGAGAGAAGTATTGGTCTTTGGTGGTTTACTTTTTAAA AATTTTGGAAAGTGTGAATCAATAACTATTTTTAATTATACTATTTGCCCATTCTTTTTCTCTGCAGTGCATTTCACAGAATAAATCCTC TAACTTGTTTTGCTGCTCTGAGCCATTTTTAAAAGTATAGAAAAAACGCCGGGTATGGTGGCTCATGCCTGTAATCCCAGCATTTTGGGA GGCCGAGACGGGTGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGATGAAACCCCGTCTCTACTAAAAATACAAAAAATT AGCCAGGCGTGGTGGTGGGCGCCTGTAGTCCCAGCTACTTGGGAGGCAGAGGCAGGAGAATGGCATGAACCCAGGAGGCAGAGCTTGCAG TGAGCCGAGATCGCGCCACTGCACTCCAGCTTGGGCAACAGAGCGAGACTCCGTCTCCAAAAAAAAAAAAAAAGTATAGAAAAAAATGGA TACTTGCAAATTTACATTTATTTTTGCACTGAGAGTTTACTGTTAAATTGTCTACACCATCATCCCTTTTTCTTTTTATCCTTAGTTCTA GTCCAAATTATTTTTGATTTGTAAATTATTAGGAAAGTTTTTATACTAGTTTTTTTAACCCTATGTATTATTACAGATGGAAGTAATTAT GGCATGTGTGAGTTATAATCTAAATTAGGGGCAAGTATCCCTTTTTTTATATGATGAAATTGTGCATAATAACTTGGCTAGGGCAAGTCT CCAAAGTAATTCAGATTTAACTCTTCACTGCTAGACCCAGTTGTGTTCAACTTTTTACATATTATTGCCAACACACTTTATCTCTCTGTG TACAGTGTTAATCTGATTTTATAAATCTATATTTTTTTCTTTAAGCAAATTTTTGTTTTAAAATTTGAAGCCAATCATAAAGATAATATA GCATAAGACATTTTCTTTTCTAAAAACAATCAGCATCATTTTAAAAGGATGAACTAATACAGGTGTATGTAATAGCAGTGTTTCCAAACT GGCAATTTATGCTTTAAATTTAAAAATAAGGTCATTTTTCTCCATCAGGGGCAAATGTTTACTTGTAATTTTCTTCCTACAGTTCGTGTT AAATTACTTTTTACTATTATTATATTGTAAACTCCTTGGGATTTGGCACCATTTAAAAATTCATCTTTGTATTCCCTTAATATTTGGAAC >97395_97395_4_USP34-FAM161A_USP34_chr2_61597456_ENST00000398571_FAM161A_chr2_62069495_ENST00000405894_length(amino acids)=1016AA_BP=416 MCENCADLVEVLNEISDVEGGDGLQLRKEHTLKIFTYINSWTQRQCLCCFKEYKHLEIFNQVVCALINLVIAQVQVLRDQLCKHCTTINI DSTWQDESNQAEEPLNIDRECNEGSTERQKSIEKKSNSTRICNLTEEESSKSSDPFSLWSTDEKEKLLLCVAKIFQIQFPLYTAYKHNTH PTIEDISTQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHIIPFRT YVIRYLCKLSDQELRQSAARNMADLMWSTVKEPLDTTLCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETS IAKELADWLISNNVVEHIFGPNLHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQADLNTSFSGVDEHAPISYEDFVNFPDIHHSNEE YFKKVEELKAAHIETMAKLEKMYQDKLHLKEVQPVVIREDSLSDSSRSVSEKNSYHPVSLMTSFSEPDLGQSSSLYVSSSEEELPNLEKE YPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKKQEE DPEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFKARPIPRST YGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVC KPFDLHASPHASIKREKILADIEADEENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRKSEKERMREYQRELEE REEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDT -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for USP34-FAM161A |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for USP34-FAM161A |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for USP34-FAM161A |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | USP34 | C0004238 | Atrial Fibrillation | 1 | CTD_human |
| Hgene | USP34 | C0235480 | Paroxysmal atrial fibrillation | 1 | CTD_human |
| Hgene | USP34 | C2585653 | Persistent atrial fibrillation | 1 | CTD_human |
| Hgene | USP34 | C3468561 | familial atrial fibrillation | 1 | CTD_human |
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