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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ABI1-GDI2 (FusionGDB2 ID:HG10006TG2665)

Fusion Gene Summary for ABI1-GDI2

check button Fusion gene summary
Fusion gene informationFusion gene name: ABI1-GDI2
Fusion gene ID: hg10006tg2665
HgeneTgene
Gene symbol

ABI1

GDI2

Gene ID

10006

2665

Gene nameabl interactor 1GDP dissociation inhibitor 2
SynonymsABI-1|ABLBP4|E3B1|NAP1BP|SSH3BP|SSH3BP1HEL-S-46e|RABGDIB
Cytomap('ABI1')('GDI2')

10p12.1

10p15.1

Type of geneprotein-codingprotein-coding
Descriptionabl interactor 1Abelson interactor 1Abl-interactor protein 1 longabl-binding protein 4eps8 SH3 domain-binding proteininteractor protein AblBP4nap1 binding proteinspectrin SH3 domain-binding protein 1rab GDP dissociation inhibitor betaGDI-2epididymis secretory sperm binding protein Li 46eguanosine diphosphate dissociation inhibitor 2rab GDI betarab GDP-dissociation inhibitor, beta
Modification date2020032720200313
UniProtAcc

Q8IZP0

.
Ensembl transtripts involved in fusion geneENST00000346832, ENST00000355394, 
ENST00000359188, ENST00000376134, 
ENST00000376137, ENST00000376138, 
ENST00000376139, ENST00000376140, 
ENST00000376142, ENST00000376160, 
ENST00000376166, ENST00000376170, 
ENST00000490841, ENST00000536334, 
ENST00000473481, 
Fusion gene scores* DoF score15 X 10 X 8=120019 X 10 X 8=1520
# samples 1520
** MAII scorelog2(15/1200*10)=-3
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(20/1520*10)=-2.92599941855622
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ABI1 [Title/Abstract] AND GDI2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointABI1(27112067)-GDI2(5842668), # samples:1
Anticipated loss of major functional domain due to fusion event.ABI1-GDI2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABI1-GDI2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABI1-GDI2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ABI1-GDI2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneABI1

GO:0018108

peptidyl-tyrosine phosphorylation

17101133


check buttonFusion gene breakpoints across ABI1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across GDI2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerERR315371ABI1chr10

27112067

-GDI2chr10

5842668

-


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Fusion Gene ORF analysis for ABI1-GDI2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000346832ENST00000380132ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000346832ENST00000380181ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000346832ENST00000479928ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000355394ENST00000380132ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000355394ENST00000380181ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000355394ENST00000479928ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000359188ENST00000380132ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000359188ENST00000380181ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000359188ENST00000479928ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376134ENST00000380132ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376134ENST00000380181ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376134ENST00000479928ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376137ENST00000380132ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376137ENST00000380181ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376137ENST00000479928ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376138ENST00000380132ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376138ENST00000380181ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376138ENST00000479928ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376139ENST00000380132ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376139ENST00000380181ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376139ENST00000479928ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376140ENST00000380132ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376140ENST00000380181ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376140ENST00000479928ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376142ENST00000380132ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376142ENST00000380181ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376142ENST00000479928ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376160ENST00000380132ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376160ENST00000380181ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376160ENST00000479928ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376166ENST00000380132ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376166ENST00000380181ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376166ENST00000479928ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376170ENST00000380132ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376170ENST00000380181ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000376170ENST00000479928ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000490841ENST00000380132ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000490841ENST00000380181ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000490841ENST00000479928ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000536334ENST00000380132ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000536334ENST00000380181ABI1chr10

27112067

-GDI2chr10

5842668

-
5CDS-intronENST00000536334ENST00000479928ABI1chr10

27112067

-GDI2chr10

5842668

-
5UTR-3CDSENST00000473481ENST00000380191ABI1chr10

27112067

-GDI2chr10

5842668

-
5UTR-intronENST00000473481ENST00000380132ABI1chr10

27112067

-GDI2chr10

5842668

-
5UTR-intronENST00000473481ENST00000380181ABI1chr10

27112067

-GDI2chr10

5842668

-
5UTR-intronENST00000473481ENST00000479928ABI1chr10

27112067

-GDI2chr10

5842668

-
In-frameENST00000346832ENST00000380191ABI1chr10

27112067

-GDI2chr10

5842668

-
In-frameENST00000355394ENST00000380191ABI1chr10

27112067

-GDI2chr10

5842668

-
In-frameENST00000359188ENST00000380191ABI1chr10

27112067

-GDI2chr10

5842668

-
In-frameENST00000376134ENST00000380191ABI1chr10

27112067

-GDI2chr10

5842668

-
In-frameENST00000376137ENST00000380191ABI1chr10

27112067

-GDI2chr10

5842668

-
In-frameENST00000376138ENST00000380191ABI1chr10

27112067

-GDI2chr10

5842668

-
In-frameENST00000376139ENST00000380191ABI1chr10

27112067

-GDI2chr10

5842668

-
In-frameENST00000376140ENST00000380191ABI1chr10

27112067

-GDI2chr10

5842668

-
In-frameENST00000376142ENST00000380191ABI1chr10

27112067

-GDI2chr10

5842668

-
In-frameENST00000376160ENST00000380191ABI1chr10

27112067

-GDI2chr10

5842668

-
In-frameENST00000376166ENST00000380191ABI1chr10

27112067

-GDI2chr10

5842668

-
In-frameENST00000376170ENST00000380191ABI1chr10

27112067

-GDI2chr10

5842668

-
In-frameENST00000490841ENST00000380191ABI1chr10

27112067

-GDI2chr10

5842668

-
In-frameENST00000536334ENST00000380191ABI1chr10

27112067

-GDI2chr10

5842668

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000376170ABI1chr1027112067-ENST00000380191GDI2chr105842668-2390314291606525
ENST00000359188ABI1chr1027112067-ENST00000380191GDI2chr105842668-2433357721649525
ENST00000376142ABI1chr1027112067-ENST00000380191GDI2chr105842668-2433357721649525
ENST00000376139ABI1chr1027112067-ENST00000380191GDI2chr105842668-24693931081685525
ENST00000376160ABI1chr1027112067-ENST00000380191GDI2chr105842668-24713951101687525
ENST00000376166ABI1chr1027112067-ENST00000380191GDI2chr105842668-24844081231700525
ENST00000376138ABI1chr1027112067-ENST00000380191GDI2chr105842668-25284521671744525
ENST00000355394ABI1chr1027112067-ENST00000380191GDI2chr105842668-25855092241801525
ENST00000490841ABI1chr1027112067-ENST00000380191GDI2chr105842668-25855092241801525
ENST00000376137ABI1chr1027112067-ENST00000380191GDI2chr105842668-25855092241801525
ENST00000346832ABI1chr1027112067-ENST00000380191GDI2chr105842668-26365602241852542
ENST00000536334ABI1chr1027112067-ENST00000380191GDI2chr105842668-25855092241801525
ENST00000376134ABI1chr1027112067-ENST00000380191GDI2chr105842668-25855092241801525
ENST00000376140ABI1chr1027112067-ENST00000380191GDI2chr105842668-236128501577525

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000376170ENST00000380191ABI1chr1027112067-GDI2chr105842668-0.0003310250.99966896
ENST00000359188ENST00000380191ABI1chr1027112067-GDI2chr105842668-0.000316320.99968374
ENST00000376142ENST00000380191ABI1chr1027112067-GDI2chr105842668-0.000316320.99968374
ENST00000376139ENST00000380191ABI1chr1027112067-GDI2chr105842668-0.0003079840.9996921
ENST00000376160ENST00000380191ABI1chr1027112067-GDI2chr105842668-0.0003065690.9996935
ENST00000376166ENST00000380191ABI1chr1027112067-GDI2chr105842668-0.0003139970.999686
ENST00000376138ENST00000380191ABI1chr1027112067-GDI2chr105842668-0.0002982770.9997017
ENST00000355394ENST00000380191ABI1chr1027112067-GDI2chr105842668-0.0002927810.99970716
ENST00000490841ENST00000380191ABI1chr1027112067-GDI2chr105842668-0.0002927810.99970716
ENST00000376137ENST00000380191ABI1chr1027112067-GDI2chr105842668-0.0002927810.99970716
ENST00000346832ENST00000380191ABI1chr1027112067-GDI2chr105842668-0.0003449020.9996551
ENST00000536334ENST00000380191ABI1chr1027112067-GDI2chr105842668-0.0002927810.99970716
ENST00000376134ENST00000380191ABI1chr1027112067-GDI2chr105842668-0.0002927810.99970716
ENST00000376140ENST00000380191ABI1chr1027112067-GDI2chr105842668-0.0003260630.99967396

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Fusion Genomic Features for ABI1-GDI2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ABI1-GDI2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:27112067/chr10:5842668)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ABI1

Q8IZP0

.
FUNCTION: May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1/c-Abl-mediated phosphorylation of ENAH. Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level. In brain, seems to regulate the dendritic outgrowth and branching as well as to determine the shape and number of synaptic contacts of developing neurons. {ECO:0000269|PubMed:11003655, ECO:0000269|PubMed:18328268}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABI1chr10:27112067chr10:5842668ENST00000346832-31245_107112497.0Domaint-SNARE coiled-coil homology
HgeneABI1chr10:27112067chr10:5842668ENST00000346832-31218_79112497.0RegionRequired for binding to WASF1
HgeneABI1chr10:27112067chr10:5842668ENST00000359188-21118_7995481.0RegionRequired for binding to WASF1
HgeneABI1chr10:27112067chr10:5842668ENST00000376138-21018_7995453.0RegionRequired for binding to WASF1
HgeneABI1chr10:27112067chr10:5842668ENST00000376139-21018_7995477.0RegionRequired for binding to WASF1
HgeneABI1chr10:27112067chr10:5842668ENST00000376140-21118_7995482.0RegionRequired for binding to WASF1
HgeneABI1chr10:27112067chr10:5842668ENST00000376142-21218_7995509.0RegionRequired for binding to WASF1
HgeneABI1chr10:27112067chr10:5842668ENST00000376166-2918_7995447.0RegionRequired for binding to WASF1
HgeneABI1chr10:27112067chr10:5842668ENST00000376170-21018_7995452.0RegionRequired for binding to WASF1
HgeneABI1chr10:27112067chr10:5842668ENST00000490841-2718_7995330.0RegionRequired for binding to WASF1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABI1chr10:27112067chr10:5842668ENST00000346832-312260_418112497.0Compositional biasNote=Pro-rich
HgeneABI1chr10:27112067chr10:5842668ENST00000359188-211260_41895481.0Compositional biasNote=Pro-rich
HgeneABI1chr10:27112067chr10:5842668ENST00000376138-210260_41895453.0Compositional biasNote=Pro-rich
HgeneABI1chr10:27112067chr10:5842668ENST00000376139-210260_41895477.0Compositional biasNote=Pro-rich
HgeneABI1chr10:27112067chr10:5842668ENST00000376140-211260_41895482.0Compositional biasNote=Pro-rich
HgeneABI1chr10:27112067chr10:5842668ENST00000376142-212260_41895509.0Compositional biasNote=Pro-rich
HgeneABI1chr10:27112067chr10:5842668ENST00000376166-29260_41895447.0Compositional biasNote=Pro-rich
HgeneABI1chr10:27112067chr10:5842668ENST00000376170-210260_41895452.0Compositional biasNote=Pro-rich
HgeneABI1chr10:27112067chr10:5842668ENST00000490841-27260_41895330.0Compositional biasNote=Pro-rich
HgeneABI1chr10:27112067chr10:5842668ENST00000346832-312446_505112497.0DomainSH3
HgeneABI1chr10:27112067chr10:5842668ENST00000359188-211446_50595481.0DomainSH3
HgeneABI1chr10:27112067chr10:5842668ENST00000359188-21145_10795481.0Domaint-SNARE coiled-coil homology
HgeneABI1chr10:27112067chr10:5842668ENST00000376138-210446_50595453.0DomainSH3
HgeneABI1chr10:27112067chr10:5842668ENST00000376138-21045_10795453.0Domaint-SNARE coiled-coil homology
HgeneABI1chr10:27112067chr10:5842668ENST00000376139-210446_50595477.0DomainSH3
HgeneABI1chr10:27112067chr10:5842668ENST00000376139-21045_10795477.0Domaint-SNARE coiled-coil homology
HgeneABI1chr10:27112067chr10:5842668ENST00000376140-211446_50595482.0DomainSH3
HgeneABI1chr10:27112067chr10:5842668ENST00000376140-21145_10795482.0Domaint-SNARE coiled-coil homology
HgeneABI1chr10:27112067chr10:5842668ENST00000376142-212446_50595509.0DomainSH3
HgeneABI1chr10:27112067chr10:5842668ENST00000376142-21245_10795509.0Domaint-SNARE coiled-coil homology
HgeneABI1chr10:27112067chr10:5842668ENST00000376166-29446_50595447.0DomainSH3
HgeneABI1chr10:27112067chr10:5842668ENST00000376166-2945_10795447.0Domaint-SNARE coiled-coil homology
HgeneABI1chr10:27112067chr10:5842668ENST00000376170-210446_50595452.0DomainSH3
HgeneABI1chr10:27112067chr10:5842668ENST00000376170-21045_10795452.0Domaint-SNARE coiled-coil homology
HgeneABI1chr10:27112067chr10:5842668ENST00000490841-27446_50595330.0DomainSH3
HgeneABI1chr10:27112067chr10:5842668ENST00000490841-2745_10795330.0Domaint-SNARE coiled-coil homology


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Fusion Gene Sequence for ABI1-GDI2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>447_447_1_ABI1-GDI2_ABI1_chr10_27112067_ENST00000346832_GDI2_chr10_5842668_ENST00000380191_length(transcript)=2636nt_BP=560nt
GAGAAATAAACGCTCGCGAGAGAACGAGGTTCAGGCGGCTGCACGAAGGGGGTGGAGGGGGGCTGGAGAGAGTGAGGAGGAAGGGGAGGA
GGTGCCGTCCCACAATACCAGGCGGGAGGGCGGGTAGGCGGTTTGTATCCGGGCTGTGAGGTGCTCGGAGCCTCGGCGGACCTTGCTGCC
TCTGTCTCTTTAACGCGAGAGGAAGCGATGCAGAGGGGTGGAAAATGGCAGAGCTGCAGATGTTACTAGAGGAGGAGATCCCGTCTGGCA
AGAGGGCGCTGATCGAGAGTTACCAGAACCTGACTCGGGTGGCAGACTACTGTGAAAACAACTACATACAGAGACATGGTTTTGCTGTGT
TGCTGTGTCTGCTCTCAAACTCCTGGCCTCAGGCTACAGACAAGAGAAAAGCTTTAGAGGAGACCAAAGCCTATACAACCCAATCTCTAG
CTAGTGTTGCTTATCAAATAAATGCATTGGCCAACAATGTACTCCAGTTGCTGGATATCCAAGCCTCTCAGCTTCGGAGAATGGAGTCTT
CCATCAATCATATCTCACAGGAATGTATCCTGTCAGGTATAATGTCAGTGAATGGCAAGAAAGTTCTTCATATGGATCGAAACCCTTACT
ACGGAGGAGAGAGTGCATCTATAACACCATTGGAAGATTTATACAAAAGATTTAAAATACCAGGATCACCACCCGAGTCAATGGGGAGAG
GAAGAGACTGGAATGTTGACTTGATTCCCAAGTTCCTTATGGCTAATGGTCAGCTGGTTAAGATGCTGCTTTATACAGAGGTAACTCGCT
ATCTGGATTTTAAAGTGACTGAAGGGAGCTTTGTCTATAAGGGTGGAAAAATCTACAAGGTTCCTTCCACTGAAGCAGAAGCCCTGGCAT
CTAGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTAGTGTATGTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTG
AAGGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAATTTGATTTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTC
TTGCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAAACCATTAATAGAATTAAACTTTACAGTGAATCTTTGGCAAGAT
ATGGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTGCCCCAAGGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCT
ATATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAAGTAATTGGTGTAAAATCTGAAGGAGAAATTGCTCGCTGTAAGC
AGCTCATCTGTGACCCCAGCTACGTAAAAGATCGGGTAGAAAAAGTGGGCCAGGTGATCAGAGTTATTTGCATCCTCAGCCACCCCATCA
AGAACACCAATGATGCCAACTCCTGCCAGATCATTATTCCACAGAACCAAGTCAATCGAAAGTCAGATATCTACGTCTGCATGATCTCCT
TTGCGCACAATGTAGCAGCACAAGGGAAGTACATTGCTATAGTTAGTACAACTGTGGAAACCAAGGAGCCTGAGAAGGAAATCAGACCAG
CTTTGGAGCTCTTGGAACCAATTGAACAGAAATTTGTTAGCATCAGTGACCTCCTGGTACCAAAAGACTTGGGAACAGAAAGCCAGATCT
TTATTTCCCGCACATATGATGCCACCACTCATTTTGAGACAACGTGTGATGACATTAAAAACATCTATAAGAGGATGACAGGATCAGAGT
TTGACTTTGAGGAAATGAAGCGCAAGAAGAATGACATCTATGGGGAAGACTAACAGCAGTACATGTTATTATGTAATTAGGACACATTTA
AAATTTGGCAAATAATGCATATAATGAAATCAATATTGTAAGGCCTGCTTTTGTAATGAAAATGGAGAGAATGAAGAGCGCTGTGCCAGT
AAATACTCCCCTTCACCTTTCTAATTATTAACTTGTTTTCATGGAGTGGCTATTCAGCATTGGCAGTTACCACATTCTGTTCAATTTAAC
CAAACTGGCTTTTTTTTTTTCTAGTGAAGTTAAACAAACATTGGGATACCGACACAGACAACTTGAGACAGTTTTTTTAATCTTTTAATC
AGTGTAGCTATGTGCTGCTGCTGCTCAAGAGCTGGATCCATACAGGTTGTGTGTCATCTGTCCTCTTGAGGTTCAGGAGATTCTAAATTG
AATATTCCACGGTTTGGGACAGCATCCGGAAGTTTTCCCTATGACTTTATATTTTGTATTATGTCAAATGTTATGGCAGGGCCCAAATAG
CATAGCCACAAGTTTGGTTTATGTGGGCATAAAATTCTAACCAAACCCCAGACATAGGGAGTCATTTGGAGAAAGCCTGTATGTGGTGTT
TTAACCTAATAAAGTTGATGAGAGAGAAGGGGAGAGGAAGCGAACATAAAGCGGGTCAAGTGTAGTGCATCTTTTGTATCTCAGGCGTGG
CTTCTTCAGTGGACCAAGCTGCAATGCAGTATTGACTTGACAGAGCCTCTACTTCTGTCTCAAAATGGCTCCAAATGATTTCTGTACTGC

>447_447_1_ABI1-GDI2_ABI1_chr10_27112067_ENST00000346832_GDI2_chr10_5842668_ENST00000380191_length(amino acids)=542AA_BP=112
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQRHGFAVLLCLLSNSWPQATDKRKALEETKAYTTQSLASVAYQINALANNVL
QLLDIQASQLRRMESSINHISQECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMA
NGQLVKMLLYTEVTRYLDFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYK
KFDLGQDVIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNG
KVIGVKSEGEIARCKQLICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIV
STTVETKEPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATTHFETTCDDIKNIYKRMTGSEFDFEEMKRKKNDIYG

--------------------------------------------------------------
>447_447_2_ABI1-GDI2_ABI1_chr10_27112067_ENST00000355394_GDI2_chr10_5842668_ENST00000380191_length(transcript)=2585nt_BP=509nt
GAGAAATAAACGCTCGCGAGAGAACGAGGTTCAGGCGGCTGCACGAAGGGGGTGGAGGGGGGCTGGAGAGAGTGAGGAGGAAGGGGAGGA
GGTGCCGTCCCACAATACCAGGCGGGAGGGCGGGTAGGCGGTTTGTATCCGGGCTGTGAGGTGCTCGGAGCCTCGGCGGACCTTGCTGCC
TCTGTCTCTTTAACGCGAGAGGAAGCGATGCAGAGGGGTGGAAAATGGCAGAGCTGCAGATGTTACTAGAGGAGGAGATCCCGTCTGGCA
AGAGGGCGCTGATCGAGAGTTACCAGAACCTGACTCGGGTGGCAGACTACTGTGAAAACAACTACATACAGGCTACAGACAAGAGAAAAG
CTTTAGAGGAGACCAAAGCCTATACAACCCAATCTCTAGCTAGTGTTGCTTATCAAATAAATGCATTGGCCAACAATGTACTCCAGTTGC
TGGATATCCAAGCCTCTCAGCTTCGGAGAATGGAGTCTTCCATCAATCATATCTCACAGGAATGTATCCTGTCAGGTATAATGTCAGTGA
ATGGCAAGAAAGTTCTTCATATGGATCGAAACCCTTACTACGGAGGAGAGAGTGCATCTATAACACCATTGGAAGATTTATACAAAAGAT
TTAAAATACCAGGATCACCACCCGAGTCAATGGGGAGAGGAAGAGACTGGAATGTTGACTTGATTCCCAAGTTCCTTATGGCTAATGGTC
AGCTGGTTAAGATGCTGCTTTATACAGAGGTAACTCGCTATCTGGATTTTAAAGTGACTGAAGGGAGCTTTGTCTATAAGGGTGGAAAAA
TCTACAAGGTTCCTTCCACTGAAGCAGAAGCCCTGGCATCTAGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTAGTGT
ATGTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTGAAGGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAATTTG
ATTTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTCTTGCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAAACCA
TTAATAGAATTAAACTTTACAGTGAATCTTTGGCAAGATATGGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTGCCCC
AAGGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCTATATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAAGTAA
TTGGTGTAAAATCTGAAGGAGAAATTGCTCGCTGTAAGCAGCTCATCTGTGACCCCAGCTACGTAAAAGATCGGGTAGAAAAAGTGGGCC
AGGTGATCAGAGTTATTTGCATCCTCAGCCACCCCATCAAGAACACCAATGATGCCAACTCCTGCCAGATCATTATTCCACAGAACCAAG
TCAATCGAAAGTCAGATATCTACGTCTGCATGATCTCCTTTGCGCACAATGTAGCAGCACAAGGGAAGTACATTGCTATAGTTAGTACAA
CTGTGGAAACCAAGGAGCCTGAGAAGGAAATCAGACCAGCTTTGGAGCTCTTGGAACCAATTGAACAGAAATTTGTTAGCATCAGTGACC
TCCTGGTACCAAAAGACTTGGGAACAGAAAGCCAGATCTTTATTTCCCGCACATATGATGCCACCACTCATTTTGAGACAACGTGTGATG
ACATTAAAAACATCTATAAGAGGATGACAGGATCAGAGTTTGACTTTGAGGAAATGAAGCGCAAGAAGAATGACATCTATGGGGAAGACT
AACAGCAGTACATGTTATTATGTAATTAGGACACATTTAAAATTTGGCAAATAATGCATATAATGAAATCAATATTGTAAGGCCTGCTTT
TGTAATGAAAATGGAGAGAATGAAGAGCGCTGTGCCAGTAAATACTCCCCTTCACCTTTCTAATTATTAACTTGTTTTCATGGAGTGGCT
ATTCAGCATTGGCAGTTACCACATTCTGTTCAATTTAACCAAACTGGCTTTTTTTTTTTCTAGTGAAGTTAAACAAACATTGGGATACCG
ACACAGACAACTTGAGACAGTTTTTTTAATCTTTTAATCAGTGTAGCTATGTGCTGCTGCTGCTCAAGAGCTGGATCCATACAGGTTGTG
TGTCATCTGTCCTCTTGAGGTTCAGGAGATTCTAAATTGAATATTCCACGGTTTGGGACAGCATCCGGAAGTTTTCCCTATGACTTTATA
TTTTGTATTATGTCAAATGTTATGGCAGGGCCCAAATAGCATAGCCACAAGTTTGGTTTATGTGGGCATAAAATTCTAACCAAACCCCAG
ACATAGGGAGTCATTTGGAGAAAGCCTGTATGTGGTGTTTTAACCTAATAAAGTTGATGAGAGAGAAGGGGAGAGGAAGCGAACATAAAG
CGGGTCAAGTGTAGTGCATCTTTTGTATCTCAGGCGTGGCTTCTTCAGTGGACCAAGCTGCAATGCAGTATTGACTTGACAGAGCCTCTA

>447_447_2_ABI1-GDI2_ABI1_chr10_27112067_ENST00000355394_GDI2_chr10_5842668_ENST00000380191_length(amino acids)=525AA_BP=95
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSI
NHISQECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYL
DFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALA
LYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQL
ICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPAL

--------------------------------------------------------------
>447_447_3_ABI1-GDI2_ABI1_chr10_27112067_ENST00000359188_GDI2_chr10_5842668_ENST00000380191_length(transcript)=2433nt_BP=357nt
GCTCGGAGCCTCGGCGGACCTTGCTGCCTCTGTCTCTTTAACGCGAGAGGAAGCGATGCAGAGGGGTGGAAAATGGCAGAGCTGCAGATG
TTACTAGAGGAGGAGATCCCGTCTGGCAAGAGGGCGCTGATCGAGAGTTACCAGAACCTGACTCGGGTGGCAGACTACTGTGAAAACAAC
TACATACAGGCTACAGACAAGAGAAAAGCTTTAGAGGAGACCAAAGCCTATACAACCCAATCTCTAGCTAGTGTTGCTTATCAAATAAAT
GCATTGGCCAACAATGTACTCCAGTTGCTGGATATCCAAGCCTCTCAGCTTCGGAGAATGGAGTCTTCCATCAATCATATCTCACAGGAA
TGTATCCTGTCAGGTATAATGTCAGTGAATGGCAAGAAAGTTCTTCATATGGATCGAAACCCTTACTACGGAGGAGAGAGTGCATCTATA
ACACCATTGGAAGATTTATACAAAAGATTTAAAATACCAGGATCACCACCCGAGTCAATGGGGAGAGGAAGAGACTGGAATGTTGACTTG
ATTCCCAAGTTCCTTATGGCTAATGGTCAGCTGGTTAAGATGCTGCTTTATACAGAGGTAACTCGCTATCTGGATTTTAAAGTGACTGAA
GGGAGCTTTGTCTATAAGGGTGGAAAAATCTACAAGGTTCCTTCCACTGAAGCAGAAGCCCTGGCATCTAGCCTAATGGGATTGTTTGAA
AAACGTCGCTTCAGGAAATTCCTAGTGTATGTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTGAAGGCATTGATCCTAAGAAGACC
ACAATGCGAGATGTGTATAAGAAATTTGATTTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTCTTGCACTTTACAGAACTGATGAT
TACTTAGATCAACCGTGTTATGAAACCATTAATAGAATTAAACTTTACAGTGAATCTTTGGCAAGATATGGCAAAAGCCCATACCTTTAT
CCACTCTATGGCCTTGGAGAACTGCCCCAAGGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCTATATGCTGAATAAACCCATTGAA
GAAATCATTGTACAGAATGGAAAAGTAATTGGTGTAAAATCTGAAGGAGAAATTGCTCGCTGTAAGCAGCTCATCTGTGACCCCAGCTAC
GTAAAAGATCGGGTAGAAAAAGTGGGCCAGGTGATCAGAGTTATTTGCATCCTCAGCCACCCCATCAAGAACACCAATGATGCCAACTCC
TGCCAGATCATTATTCCACAGAACCAAGTCAATCGAAAGTCAGATATCTACGTCTGCATGATCTCCTTTGCGCACAATGTAGCAGCACAA
GGGAAGTACATTGCTATAGTTAGTACAACTGTGGAAACCAAGGAGCCTGAGAAGGAAATCAGACCAGCTTTGGAGCTCTTGGAACCAATT
GAACAGAAATTTGTTAGCATCAGTGACCTCCTGGTACCAAAAGACTTGGGAACAGAAAGCCAGATCTTTATTTCCCGCACATATGATGCC
ACCACTCATTTTGAGACAACGTGTGATGACATTAAAAACATCTATAAGAGGATGACAGGATCAGAGTTTGACTTTGAGGAAATGAAGCGC
AAGAAGAATGACATCTATGGGGAAGACTAACAGCAGTACATGTTATTATGTAATTAGGACACATTTAAAATTTGGCAAATAATGCATATA
ATGAAATCAATATTGTAAGGCCTGCTTTTGTAATGAAAATGGAGAGAATGAAGAGCGCTGTGCCAGTAAATACTCCCCTTCACCTTTCTA
ATTATTAACTTGTTTTCATGGAGTGGCTATTCAGCATTGGCAGTTACCACATTCTGTTCAATTTAACCAAACTGGCTTTTTTTTTTTCTA
GTGAAGTTAAACAAACATTGGGATACCGACACAGACAACTTGAGACAGTTTTTTTAATCTTTTAATCAGTGTAGCTATGTGCTGCTGCTG
CTCAAGAGCTGGATCCATACAGGTTGTGTGTCATCTGTCCTCTTGAGGTTCAGGAGATTCTAAATTGAATATTCCACGGTTTGGGACAGC
ATCCGGAAGTTTTCCCTATGACTTTATATTTTGTATTATGTCAAATGTTATGGCAGGGCCCAAATAGCATAGCCACAAGTTTGGTTTATG
TGGGCATAAAATTCTAACCAAACCCCAGACATAGGGAGTCATTTGGAGAAAGCCTGTATGTGGTGTTTTAACCTAATAAAGTTGATGAGA
GAGAAGGGGAGAGGAAGCGAACATAAAGCGGGTCAAGTGTAGTGCATCTTTTGTATCTCAGGCGTGGCTTCTTCAGTGGACCAAGCTGCA
ATGCAGTATTGACTTGACAGAGCCTCTACTTCTGTCTCAAAATGGCTCCAAATGATTTCTGTACTGCAAAATAAAGCCAAATTCTGGAAA

>447_447_3_ABI1-GDI2_ABI1_chr10_27112067_ENST00000359188_GDI2_chr10_5842668_ENST00000380191_length(amino acids)=525AA_BP=95
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSI
NHISQECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYL
DFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALA
LYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQL
ICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPAL

--------------------------------------------------------------
>447_447_4_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376134_GDI2_chr10_5842668_ENST00000380191_length(transcript)=2585nt_BP=509nt
GAGAAATAAACGCTCGCGAGAGAACGAGGTTCAGGCGGCTGCACGAAGGGGGTGGAGGGGGGCTGGAGAGAGTGAGGAGGAAGGGGAGGA
GGTGCCGTCCCACAATACCAGGCGGGAGGGCGGGTAGGCGGTTTGTATCCGGGCTGTGAGGTGCTCGGAGCCTCGGCGGACCTTGCTGCC
TCTGTCTCTTTAACGCGAGAGGAAGCGATGCAGAGGGGTGGAAAATGGCAGAGCTGCAGATGTTACTAGAGGAGGAGATCCCGTCTGGCA
AGAGGGCGCTGATCGAGAGTTACCAGAACCTGACTCGGGTGGCAGACTACTGTGAAAACAACTACATACAGGCTACAGACAAGAGAAAAG
CTTTAGAGGAGACCAAAGCCTATACAACCCAATCTCTAGCTAGTGTTGCTTATCAAATAAATGCATTGGCCAACAATGTACTCCAGTTGC
TGGATATCCAAGCCTCTCAGCTTCGGAGAATGGAGTCTTCCATCAATCATATCTCACAGGAATGTATCCTGTCAGGTATAATGTCAGTGA
ATGGCAAGAAAGTTCTTCATATGGATCGAAACCCTTACTACGGAGGAGAGAGTGCATCTATAACACCATTGGAAGATTTATACAAAAGAT
TTAAAATACCAGGATCACCACCCGAGTCAATGGGGAGAGGAAGAGACTGGAATGTTGACTTGATTCCCAAGTTCCTTATGGCTAATGGTC
AGCTGGTTAAGATGCTGCTTTATACAGAGGTAACTCGCTATCTGGATTTTAAAGTGACTGAAGGGAGCTTTGTCTATAAGGGTGGAAAAA
TCTACAAGGTTCCTTCCACTGAAGCAGAAGCCCTGGCATCTAGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTAGTGT
ATGTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTGAAGGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAATTTG
ATTTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTCTTGCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAAACCA
TTAATAGAATTAAACTTTACAGTGAATCTTTGGCAAGATATGGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTGCCCC
AAGGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCTATATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAAGTAA
TTGGTGTAAAATCTGAAGGAGAAATTGCTCGCTGTAAGCAGCTCATCTGTGACCCCAGCTACGTAAAAGATCGGGTAGAAAAAGTGGGCC
AGGTGATCAGAGTTATTTGCATCCTCAGCCACCCCATCAAGAACACCAATGATGCCAACTCCTGCCAGATCATTATTCCACAGAACCAAG
TCAATCGAAAGTCAGATATCTACGTCTGCATGATCTCCTTTGCGCACAATGTAGCAGCACAAGGGAAGTACATTGCTATAGTTAGTACAA
CTGTGGAAACCAAGGAGCCTGAGAAGGAAATCAGACCAGCTTTGGAGCTCTTGGAACCAATTGAACAGAAATTTGTTAGCATCAGTGACC
TCCTGGTACCAAAAGACTTGGGAACAGAAAGCCAGATCTTTATTTCCCGCACATATGATGCCACCACTCATTTTGAGACAACGTGTGATG
ACATTAAAAACATCTATAAGAGGATGACAGGATCAGAGTTTGACTTTGAGGAAATGAAGCGCAAGAAGAATGACATCTATGGGGAAGACT
AACAGCAGTACATGTTATTATGTAATTAGGACACATTTAAAATTTGGCAAATAATGCATATAATGAAATCAATATTGTAAGGCCTGCTTT
TGTAATGAAAATGGAGAGAATGAAGAGCGCTGTGCCAGTAAATACTCCCCTTCACCTTTCTAATTATTAACTTGTTTTCATGGAGTGGCT
ATTCAGCATTGGCAGTTACCACATTCTGTTCAATTTAACCAAACTGGCTTTTTTTTTTTCTAGTGAAGTTAAACAAACATTGGGATACCG
ACACAGACAACTTGAGACAGTTTTTTTAATCTTTTAATCAGTGTAGCTATGTGCTGCTGCTGCTCAAGAGCTGGATCCATACAGGTTGTG
TGTCATCTGTCCTCTTGAGGTTCAGGAGATTCTAAATTGAATATTCCACGGTTTGGGACAGCATCCGGAAGTTTTCCCTATGACTTTATA
TTTTGTATTATGTCAAATGTTATGGCAGGGCCCAAATAGCATAGCCACAAGTTTGGTTTATGTGGGCATAAAATTCTAACCAAACCCCAG
ACATAGGGAGTCATTTGGAGAAAGCCTGTATGTGGTGTTTTAACCTAATAAAGTTGATGAGAGAGAAGGGGAGAGGAAGCGAACATAAAG
CGGGTCAAGTGTAGTGCATCTTTTGTATCTCAGGCGTGGCTTCTTCAGTGGACCAAGCTGCAATGCAGTATTGACTTGACAGAGCCTCTA

>447_447_4_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376134_GDI2_chr10_5842668_ENST00000380191_length(amino acids)=525AA_BP=95
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSI
NHISQECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYL
DFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALA
LYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQL
ICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPAL

--------------------------------------------------------------
>447_447_5_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376137_GDI2_chr10_5842668_ENST00000380191_length(transcript)=2585nt_BP=509nt
GAGAAATAAACGCTCGCGAGAGAACGAGGTTCAGGCGGCTGCACGAAGGGGGTGGAGGGGGGCTGGAGAGAGTGAGGAGGAAGGGGAGGA
GGTGCCGTCCCACAATACCAGGCGGGAGGGCGGGTAGGCGGTTTGTATCCGGGCTGTGAGGTGCTCGGAGCCTCGGCGGACCTTGCTGCC
TCTGTCTCTTTAACGCGAGAGGAAGCGATGCAGAGGGGTGGAAAATGGCAGAGCTGCAGATGTTACTAGAGGAGGAGATCCCGTCTGGCA
AGAGGGCGCTGATCGAGAGTTACCAGAACCTGACTCGGGTGGCAGACTACTGTGAAAACAACTACATACAGGCTACAGACAAGAGAAAAG
CTTTAGAGGAGACCAAAGCCTATACAACCCAATCTCTAGCTAGTGTTGCTTATCAAATAAATGCATTGGCCAACAATGTACTCCAGTTGC
TGGATATCCAAGCCTCTCAGCTTCGGAGAATGGAGTCTTCCATCAATCATATCTCACAGGAATGTATCCTGTCAGGTATAATGTCAGTGA
ATGGCAAGAAAGTTCTTCATATGGATCGAAACCCTTACTACGGAGGAGAGAGTGCATCTATAACACCATTGGAAGATTTATACAAAAGAT
TTAAAATACCAGGATCACCACCCGAGTCAATGGGGAGAGGAAGAGACTGGAATGTTGACTTGATTCCCAAGTTCCTTATGGCTAATGGTC
AGCTGGTTAAGATGCTGCTTTATACAGAGGTAACTCGCTATCTGGATTTTAAAGTGACTGAAGGGAGCTTTGTCTATAAGGGTGGAAAAA
TCTACAAGGTTCCTTCCACTGAAGCAGAAGCCCTGGCATCTAGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTAGTGT
ATGTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTGAAGGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAATTTG
ATTTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTCTTGCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAAACCA
TTAATAGAATTAAACTTTACAGTGAATCTTTGGCAAGATATGGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTGCCCC
AAGGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCTATATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAAGTAA
TTGGTGTAAAATCTGAAGGAGAAATTGCTCGCTGTAAGCAGCTCATCTGTGACCCCAGCTACGTAAAAGATCGGGTAGAAAAAGTGGGCC
AGGTGATCAGAGTTATTTGCATCCTCAGCCACCCCATCAAGAACACCAATGATGCCAACTCCTGCCAGATCATTATTCCACAGAACCAAG
TCAATCGAAAGTCAGATATCTACGTCTGCATGATCTCCTTTGCGCACAATGTAGCAGCACAAGGGAAGTACATTGCTATAGTTAGTACAA
CTGTGGAAACCAAGGAGCCTGAGAAGGAAATCAGACCAGCTTTGGAGCTCTTGGAACCAATTGAACAGAAATTTGTTAGCATCAGTGACC
TCCTGGTACCAAAAGACTTGGGAACAGAAAGCCAGATCTTTATTTCCCGCACATATGATGCCACCACTCATTTTGAGACAACGTGTGATG
ACATTAAAAACATCTATAAGAGGATGACAGGATCAGAGTTTGACTTTGAGGAAATGAAGCGCAAGAAGAATGACATCTATGGGGAAGACT
AACAGCAGTACATGTTATTATGTAATTAGGACACATTTAAAATTTGGCAAATAATGCATATAATGAAATCAATATTGTAAGGCCTGCTTT
TGTAATGAAAATGGAGAGAATGAAGAGCGCTGTGCCAGTAAATACTCCCCTTCACCTTTCTAATTATTAACTTGTTTTCATGGAGTGGCT
ATTCAGCATTGGCAGTTACCACATTCTGTTCAATTTAACCAAACTGGCTTTTTTTTTTTCTAGTGAAGTTAAACAAACATTGGGATACCG
ACACAGACAACTTGAGACAGTTTTTTTAATCTTTTAATCAGTGTAGCTATGTGCTGCTGCTGCTCAAGAGCTGGATCCATACAGGTTGTG
TGTCATCTGTCCTCTTGAGGTTCAGGAGATTCTAAATTGAATATTCCACGGTTTGGGACAGCATCCGGAAGTTTTCCCTATGACTTTATA
TTTTGTATTATGTCAAATGTTATGGCAGGGCCCAAATAGCATAGCCACAAGTTTGGTTTATGTGGGCATAAAATTCTAACCAAACCCCAG
ACATAGGGAGTCATTTGGAGAAAGCCTGTATGTGGTGTTTTAACCTAATAAAGTTGATGAGAGAGAAGGGGAGAGGAAGCGAACATAAAG
CGGGTCAAGTGTAGTGCATCTTTTGTATCTCAGGCGTGGCTTCTTCAGTGGACCAAGCTGCAATGCAGTATTGACTTGACAGAGCCTCTA

>447_447_5_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376137_GDI2_chr10_5842668_ENST00000380191_length(amino acids)=525AA_BP=95
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSI
NHISQECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYL
DFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALA
LYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQL
ICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPAL

--------------------------------------------------------------
>447_447_6_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376138_GDI2_chr10_5842668_ENST00000380191_length(transcript)=2528nt_BP=452nt
GGGGGCTGGAGAGAGTGAGGAGGAAGGGGAGGAGGTGCCGTCCCACAATACCAGGCGGGAGGGCGGGTAGGCGGTTTGTATCCGGGCTGT
GAGGTGCTCGGAGCCTCGGCGGACCTTGCTGCCTCTGTCTCTTTAACGCGAGAGGAAGCGATGCAGAGGGGTGGAAAATGGCAGAGCTGC
AGATGTTACTAGAGGAGGAGATCCCGTCTGGCAAGAGGGCGCTGATCGAGAGTTACCAGAACCTGACTCGGGTGGCAGACTACTGTGAAA
ACAACTACATACAGGCTACAGACAAGAGAAAAGCTTTAGAGGAGACCAAAGCCTATACAACCCAATCTCTAGCTAGTGTTGCTTATCAAA
TAAATGCATTGGCCAACAATGTACTCCAGTTGCTGGATATCCAAGCCTCTCAGCTTCGGAGAATGGAGTCTTCCATCAATCATATCTCAC
AGGAATGTATCCTGTCAGGTATAATGTCAGTGAATGGCAAGAAAGTTCTTCATATGGATCGAAACCCTTACTACGGAGGAGAGAGTGCAT
CTATAACACCATTGGAAGATTTATACAAAAGATTTAAAATACCAGGATCACCACCCGAGTCAATGGGGAGAGGAAGAGACTGGAATGTTG
ACTTGATTCCCAAGTTCCTTATGGCTAATGGTCAGCTGGTTAAGATGCTGCTTTATACAGAGGTAACTCGCTATCTGGATTTTAAAGTGA
CTGAAGGGAGCTTTGTCTATAAGGGTGGAAAAATCTACAAGGTTCCTTCCACTGAAGCAGAAGCCCTGGCATCTAGCCTAATGGGATTGT
TTGAAAAACGTCGCTTCAGGAAATTCCTAGTGTATGTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTGAAGGCATTGATCCTAAGA
AGACCACAATGCGAGATGTGTATAAGAAATTTGATTTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTCTTGCACTTTACAGAACTG
ATGATTACTTAGATCAACCGTGTTATGAAACCATTAATAGAATTAAACTTTACAGTGAATCTTTGGCAAGATATGGCAAAAGCCCATACC
TTTATCCACTCTATGGCCTTGGAGAACTGCCCCAAGGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCTATATGCTGAATAAACCCA
TTGAAGAAATCATTGTACAGAATGGAAAAGTAATTGGTGTAAAATCTGAAGGAGAAATTGCTCGCTGTAAGCAGCTCATCTGTGACCCCA
GCTACGTAAAAGATCGGGTAGAAAAAGTGGGCCAGGTGATCAGAGTTATTTGCATCCTCAGCCACCCCATCAAGAACACCAATGATGCCA
ACTCCTGCCAGATCATTATTCCACAGAACCAAGTCAATCGAAAGTCAGATATCTACGTCTGCATGATCTCCTTTGCGCACAATGTAGCAG
CACAAGGGAAGTACATTGCTATAGTTAGTACAACTGTGGAAACCAAGGAGCCTGAGAAGGAAATCAGACCAGCTTTGGAGCTCTTGGAAC
CAATTGAACAGAAATTTGTTAGCATCAGTGACCTCCTGGTACCAAAAGACTTGGGAACAGAAAGCCAGATCTTTATTTCCCGCACATATG
ATGCCACCACTCATTTTGAGACAACGTGTGATGACATTAAAAACATCTATAAGAGGATGACAGGATCAGAGTTTGACTTTGAGGAAATGA
AGCGCAAGAAGAATGACATCTATGGGGAAGACTAACAGCAGTACATGTTATTATGTAATTAGGACACATTTAAAATTTGGCAAATAATGC
ATATAATGAAATCAATATTGTAAGGCCTGCTTTTGTAATGAAAATGGAGAGAATGAAGAGCGCTGTGCCAGTAAATACTCCCCTTCACCT
TTCTAATTATTAACTTGTTTTCATGGAGTGGCTATTCAGCATTGGCAGTTACCACATTCTGTTCAATTTAACCAAACTGGCTTTTTTTTT
TTCTAGTGAAGTTAAACAAACATTGGGATACCGACACAGACAACTTGAGACAGTTTTTTTAATCTTTTAATCAGTGTAGCTATGTGCTGC
TGCTGCTCAAGAGCTGGATCCATACAGGTTGTGTGTCATCTGTCCTCTTGAGGTTCAGGAGATTCTAAATTGAATATTCCACGGTTTGGG
ACAGCATCCGGAAGTTTTCCCTATGACTTTATATTTTGTATTATGTCAAATGTTATGGCAGGGCCCAAATAGCATAGCCACAAGTTTGGT
TTATGTGGGCATAAAATTCTAACCAAACCCCAGACATAGGGAGTCATTTGGAGAAAGCCTGTATGTGGTGTTTTAACCTAATAAAGTTGA
TGAGAGAGAAGGGGAGAGGAAGCGAACATAAAGCGGGTCAAGTGTAGTGCATCTTTTGTATCTCAGGCGTGGCTTCTTCAGTGGACCAAG
CTGCAATGCAGTATTGACTTGACAGAGCCTCTACTTCTGTCTCAAAATGGCTCCAAATGATTTCTGTACTGCAAAATAAAGCCAAATTCT

>447_447_6_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376138_GDI2_chr10_5842668_ENST00000380191_length(amino acids)=525AA_BP=95
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSI
NHISQECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYL
DFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALA
LYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQL
ICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPAL

--------------------------------------------------------------
>447_447_7_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376139_GDI2_chr10_5842668_ENST00000380191_length(transcript)=2469nt_BP=393nt
AGGGCGGGTAGGCGGTTTGTATCCGGGCTGTGAGGTGCTCGGAGCCTCGGCGGACCTTGCTGCCTCTGTCTCTTTAACGCGAGAGGAAGC
GATGCAGAGGGGTGGAAAATGGCAGAGCTGCAGATGTTACTAGAGGAGGAGATCCCGTCTGGCAAGAGGGCGCTGATCGAGAGTTACCAG
AACCTGACTCGGGTGGCAGACTACTGTGAAAACAACTACATACAGGCTACAGACAAGAGAAAAGCTTTAGAGGAGACCAAAGCCTATACA
ACCCAATCTCTAGCTAGTGTTGCTTATCAAATAAATGCATTGGCCAACAATGTACTCCAGTTGCTGGATATCCAAGCCTCTCAGCTTCGG
AGAATGGAGTCTTCCATCAATCATATCTCACAGGAATGTATCCTGTCAGGTATAATGTCAGTGAATGGCAAGAAAGTTCTTCATATGGAT
CGAAACCCTTACTACGGAGGAGAGAGTGCATCTATAACACCATTGGAAGATTTATACAAAAGATTTAAAATACCAGGATCACCACCCGAG
TCAATGGGGAGAGGAAGAGACTGGAATGTTGACTTGATTCCCAAGTTCCTTATGGCTAATGGTCAGCTGGTTAAGATGCTGCTTTATACA
GAGGTAACTCGCTATCTGGATTTTAAAGTGACTGAAGGGAGCTTTGTCTATAAGGGTGGAAAAATCTACAAGGTTCCTTCCACTGAAGCA
GAAGCCCTGGCATCTAGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTAGTGTATGTTGCCAACTTCGATGAAAAAGAT
CCAAGAACTTTTGAAGGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAATTTGATTTGGGTCAAGACGTTATAGATTTT
ACTGGTCATGCTCTTGCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAAACCATTAATAGAATTAAACTTTACAGTGAA
TCTTTGGCAAGATATGGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTGCCCCAAGGATTTGCAAGGCTAAGTGCTATT
TATGGAGGTACCTATATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAAGTAATTGGTGTAAAATCTGAAGGAGAAATT
GCTCGCTGTAAGCAGCTCATCTGTGACCCCAGCTACGTAAAAGATCGGGTAGAAAAAGTGGGCCAGGTGATCAGAGTTATTTGCATCCTC
AGCCACCCCATCAAGAACACCAATGATGCCAACTCCTGCCAGATCATTATTCCACAGAACCAAGTCAATCGAAAGTCAGATATCTACGTC
TGCATGATCTCCTTTGCGCACAATGTAGCAGCACAAGGGAAGTACATTGCTATAGTTAGTACAACTGTGGAAACCAAGGAGCCTGAGAAG
GAAATCAGACCAGCTTTGGAGCTCTTGGAACCAATTGAACAGAAATTTGTTAGCATCAGTGACCTCCTGGTACCAAAAGACTTGGGAACA
GAAAGCCAGATCTTTATTTCCCGCACATATGATGCCACCACTCATTTTGAGACAACGTGTGATGACATTAAAAACATCTATAAGAGGATG
ACAGGATCAGAGTTTGACTTTGAGGAAATGAAGCGCAAGAAGAATGACATCTATGGGGAAGACTAACAGCAGTACATGTTATTATGTAAT
TAGGACACATTTAAAATTTGGCAAATAATGCATATAATGAAATCAATATTGTAAGGCCTGCTTTTGTAATGAAAATGGAGAGAATGAAGA
GCGCTGTGCCAGTAAATACTCCCCTTCACCTTTCTAATTATTAACTTGTTTTCATGGAGTGGCTATTCAGCATTGGCAGTTACCACATTC
TGTTCAATTTAACCAAACTGGCTTTTTTTTTTTCTAGTGAAGTTAAACAAACATTGGGATACCGACACAGACAACTTGAGACAGTTTTTT
TAATCTTTTAATCAGTGTAGCTATGTGCTGCTGCTGCTCAAGAGCTGGATCCATACAGGTTGTGTGTCATCTGTCCTCTTGAGGTTCAGG
AGATTCTAAATTGAATATTCCACGGTTTGGGACAGCATCCGGAAGTTTTCCCTATGACTTTATATTTTGTATTATGTCAAATGTTATGGC
AGGGCCCAAATAGCATAGCCACAAGTTTGGTTTATGTGGGCATAAAATTCTAACCAAACCCCAGACATAGGGAGTCATTTGGAGAAAGCC
TGTATGTGGTGTTTTAACCTAATAAAGTTGATGAGAGAGAAGGGGAGAGGAAGCGAACATAAAGCGGGTCAAGTGTAGTGCATCTTTTGT
ATCTCAGGCGTGGCTTCTTCAGTGGACCAAGCTGCAATGCAGTATTGACTTGACAGAGCCTCTACTTCTGTCTCAAAATGGCTCCAAATG

>447_447_7_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376139_GDI2_chr10_5842668_ENST00000380191_length(amino acids)=525AA_BP=95
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSI
NHISQECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYL
DFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALA
LYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQL
ICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPAL

--------------------------------------------------------------
>447_447_8_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376140_GDI2_chr10_5842668_ENST00000380191_length(transcript)=2361nt_BP=285nt
ATGGCAGAGCTGCAGATGTTACTAGAGGAGGAGATCCCGTCTGGCAAGAGGGCGCTGATCGAGAGTTACCAGAACCTGACTCGGGTGGCA
GACTACTGTGAAAACAACTACATACAGGCTACAGACAAGAGAAAAGCTTTAGAGGAGACCAAAGCCTATACAACCCAATCTCTAGCTAGT
GTTGCTTATCAAATAAATGCATTGGCCAACAATGTACTCCAGTTGCTGGATATCCAAGCCTCTCAGCTTCGGAGAATGGAGTCTTCCATC
AATCATATCTCACAGGAATGTATCCTGTCAGGTATAATGTCAGTGAATGGCAAGAAAGTTCTTCATATGGATCGAAACCCTTACTACGGA
GGAGAGAGTGCATCTATAACACCATTGGAAGATTTATACAAAAGATTTAAAATACCAGGATCACCACCCGAGTCAATGGGGAGAGGAAGA
GACTGGAATGTTGACTTGATTCCCAAGTTCCTTATGGCTAATGGTCAGCTGGTTAAGATGCTGCTTTATACAGAGGTAACTCGCTATCTG
GATTTTAAAGTGACTGAAGGGAGCTTTGTCTATAAGGGTGGAAAAATCTACAAGGTTCCTTCCACTGAAGCAGAAGCCCTGGCATCTAGC
CTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTAGTGTATGTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTGAAGGC
ATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAATTTGATTTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTCTTGCA
CTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAAACCATTAATAGAATTAAACTTTACAGTGAATCTTTGGCAAGATATGGC
AAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTGCCCCAAGGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCTATATG
CTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAAGTAATTGGTGTAAAATCTGAAGGAGAAATTGCTCGCTGTAAGCAGCTC
ATCTGTGACCCCAGCTACGTAAAAGATCGGGTAGAAAAAGTGGGCCAGGTGATCAGAGTTATTTGCATCCTCAGCCACCCCATCAAGAAC
ACCAATGATGCCAACTCCTGCCAGATCATTATTCCACAGAACCAAGTCAATCGAAAGTCAGATATCTACGTCTGCATGATCTCCTTTGCG
CACAATGTAGCAGCACAAGGGAAGTACATTGCTATAGTTAGTACAACTGTGGAAACCAAGGAGCCTGAGAAGGAAATCAGACCAGCTTTG
GAGCTCTTGGAACCAATTGAACAGAAATTTGTTAGCATCAGTGACCTCCTGGTACCAAAAGACTTGGGAACAGAAAGCCAGATCTTTATT
TCCCGCACATATGATGCCACCACTCATTTTGAGACAACGTGTGATGACATTAAAAACATCTATAAGAGGATGACAGGATCAGAGTTTGAC
TTTGAGGAAATGAAGCGCAAGAAGAATGACATCTATGGGGAAGACTAACAGCAGTACATGTTATTATGTAATTAGGACACATTTAAAATT
TGGCAAATAATGCATATAATGAAATCAATATTGTAAGGCCTGCTTTTGTAATGAAAATGGAGAGAATGAAGAGCGCTGTGCCAGTAAATA
CTCCCCTTCACCTTTCTAATTATTAACTTGTTTTCATGGAGTGGCTATTCAGCATTGGCAGTTACCACATTCTGTTCAATTTAACCAAAC
TGGCTTTTTTTTTTTCTAGTGAAGTTAAACAAACATTGGGATACCGACACAGACAACTTGAGACAGTTTTTTTAATCTTTTAATCAGTGT
AGCTATGTGCTGCTGCTGCTCAAGAGCTGGATCCATACAGGTTGTGTGTCATCTGTCCTCTTGAGGTTCAGGAGATTCTAAATTGAATAT
TCCACGGTTTGGGACAGCATCCGGAAGTTTTCCCTATGACTTTATATTTTGTATTATGTCAAATGTTATGGCAGGGCCCAAATAGCATAG
CCACAAGTTTGGTTTATGTGGGCATAAAATTCTAACCAAACCCCAGACATAGGGAGTCATTTGGAGAAAGCCTGTATGTGGTGTTTTAAC
CTAATAAAGTTGATGAGAGAGAAGGGGAGAGGAAGCGAACATAAAGCGGGTCAAGTGTAGTGCATCTTTTGTATCTCAGGCGTGGCTTCT
TCAGTGGACCAAGCTGCAATGCAGTATTGACTTGACAGAGCCTCTACTTCTGTCTCAAAATGGCTCCAAATGATTTCTGTACTGCAAAAT

>447_447_8_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376140_GDI2_chr10_5842668_ENST00000380191_length(amino acids)=525AA_BP=95
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSI
NHISQECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYL
DFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALA
LYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQL
ICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPAL

--------------------------------------------------------------
>447_447_9_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376142_GDI2_chr10_5842668_ENST00000380191_length(transcript)=2433nt_BP=357nt
GCTCGGAGCCTCGGCGGACCTTGCTGCCTCTGTCTCTTTAACGCGAGAGGAAGCGATGCAGAGGGGTGGAAAATGGCAGAGCTGCAGATG
TTACTAGAGGAGGAGATCCCGTCTGGCAAGAGGGCGCTGATCGAGAGTTACCAGAACCTGACTCGGGTGGCAGACTACTGTGAAAACAAC
TACATACAGGCTACAGACAAGAGAAAAGCTTTAGAGGAGACCAAAGCCTATACAACCCAATCTCTAGCTAGTGTTGCTTATCAAATAAAT
GCATTGGCCAACAATGTACTCCAGTTGCTGGATATCCAAGCCTCTCAGCTTCGGAGAATGGAGTCTTCCATCAATCATATCTCACAGGAA
TGTATCCTGTCAGGTATAATGTCAGTGAATGGCAAGAAAGTTCTTCATATGGATCGAAACCCTTACTACGGAGGAGAGAGTGCATCTATA
ACACCATTGGAAGATTTATACAAAAGATTTAAAATACCAGGATCACCACCCGAGTCAATGGGGAGAGGAAGAGACTGGAATGTTGACTTG
ATTCCCAAGTTCCTTATGGCTAATGGTCAGCTGGTTAAGATGCTGCTTTATACAGAGGTAACTCGCTATCTGGATTTTAAAGTGACTGAA
GGGAGCTTTGTCTATAAGGGTGGAAAAATCTACAAGGTTCCTTCCACTGAAGCAGAAGCCCTGGCATCTAGCCTAATGGGATTGTTTGAA
AAACGTCGCTTCAGGAAATTCCTAGTGTATGTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTGAAGGCATTGATCCTAAGAAGACC
ACAATGCGAGATGTGTATAAGAAATTTGATTTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTCTTGCACTTTACAGAACTGATGAT
TACTTAGATCAACCGTGTTATGAAACCATTAATAGAATTAAACTTTACAGTGAATCTTTGGCAAGATATGGCAAAAGCCCATACCTTTAT
CCACTCTATGGCCTTGGAGAACTGCCCCAAGGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCTATATGCTGAATAAACCCATTGAA
GAAATCATTGTACAGAATGGAAAAGTAATTGGTGTAAAATCTGAAGGAGAAATTGCTCGCTGTAAGCAGCTCATCTGTGACCCCAGCTAC
GTAAAAGATCGGGTAGAAAAAGTGGGCCAGGTGATCAGAGTTATTTGCATCCTCAGCCACCCCATCAAGAACACCAATGATGCCAACTCC
TGCCAGATCATTATTCCACAGAACCAAGTCAATCGAAAGTCAGATATCTACGTCTGCATGATCTCCTTTGCGCACAATGTAGCAGCACAA
GGGAAGTACATTGCTATAGTTAGTACAACTGTGGAAACCAAGGAGCCTGAGAAGGAAATCAGACCAGCTTTGGAGCTCTTGGAACCAATT
GAACAGAAATTTGTTAGCATCAGTGACCTCCTGGTACCAAAAGACTTGGGAACAGAAAGCCAGATCTTTATTTCCCGCACATATGATGCC
ACCACTCATTTTGAGACAACGTGTGATGACATTAAAAACATCTATAAGAGGATGACAGGATCAGAGTTTGACTTTGAGGAAATGAAGCGC
AAGAAGAATGACATCTATGGGGAAGACTAACAGCAGTACATGTTATTATGTAATTAGGACACATTTAAAATTTGGCAAATAATGCATATA
ATGAAATCAATATTGTAAGGCCTGCTTTTGTAATGAAAATGGAGAGAATGAAGAGCGCTGTGCCAGTAAATACTCCCCTTCACCTTTCTA
ATTATTAACTTGTTTTCATGGAGTGGCTATTCAGCATTGGCAGTTACCACATTCTGTTCAATTTAACCAAACTGGCTTTTTTTTTTTCTA
GTGAAGTTAAACAAACATTGGGATACCGACACAGACAACTTGAGACAGTTTTTTTAATCTTTTAATCAGTGTAGCTATGTGCTGCTGCTG
CTCAAGAGCTGGATCCATACAGGTTGTGTGTCATCTGTCCTCTTGAGGTTCAGGAGATTCTAAATTGAATATTCCACGGTTTGGGACAGC
ATCCGGAAGTTTTCCCTATGACTTTATATTTTGTATTATGTCAAATGTTATGGCAGGGCCCAAATAGCATAGCCACAAGTTTGGTTTATG
TGGGCATAAAATTCTAACCAAACCCCAGACATAGGGAGTCATTTGGAGAAAGCCTGTATGTGGTGTTTTAACCTAATAAAGTTGATGAGA
GAGAAGGGGAGAGGAAGCGAACATAAAGCGGGTCAAGTGTAGTGCATCTTTTGTATCTCAGGCGTGGCTTCTTCAGTGGACCAAGCTGCA
ATGCAGTATTGACTTGACAGAGCCTCTACTTCTGTCTCAAAATGGCTCCAAATGATTTCTGTACTGCAAAATAAAGCCAAATTCTGGAAA

>447_447_9_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376142_GDI2_chr10_5842668_ENST00000380191_length(amino acids)=525AA_BP=95
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSI
NHISQECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYL
DFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALA
LYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQL
ICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPAL

--------------------------------------------------------------
>447_447_10_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376160_GDI2_chr10_5842668_ENST00000380191_length(transcript)=2471nt_BP=395nt
GGAGGGCGGGTAGGCGGTTTGTATCCGGGCTGTGAGGTGCTCGGAGCCTCGGCGGACCTTGCTGCCTCTGTCTCTTTAACGCGAGAGGAA
GCGATGCAGAGGGGTGGAAAATGGCAGAGCTGCAGATGTTACTAGAGGAGGAGATCCCGTCTGGCAAGAGGGCGCTGATCGAGAGTTACC
AGAACCTGACTCGGGTGGCAGACTACTGTGAAAACAACTACATACAGGCTACAGACAAGAGAAAAGCTTTAGAGGAGACCAAAGCCTATA
CAACCCAATCTCTAGCTAGTGTTGCTTATCAAATAAATGCATTGGCCAACAATGTACTCCAGTTGCTGGATATCCAAGCCTCTCAGCTTC
GGAGAATGGAGTCTTCCATCAATCATATCTCACAGGAATGTATCCTGTCAGGTATAATGTCAGTGAATGGCAAGAAAGTTCTTCATATGG
ATCGAAACCCTTACTACGGAGGAGAGAGTGCATCTATAACACCATTGGAAGATTTATACAAAAGATTTAAAATACCAGGATCACCACCCG
AGTCAATGGGGAGAGGAAGAGACTGGAATGTTGACTTGATTCCCAAGTTCCTTATGGCTAATGGTCAGCTGGTTAAGATGCTGCTTTATA
CAGAGGTAACTCGCTATCTGGATTTTAAAGTGACTGAAGGGAGCTTTGTCTATAAGGGTGGAAAAATCTACAAGGTTCCTTCCACTGAAG
CAGAAGCCCTGGCATCTAGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTAGTGTATGTTGCCAACTTCGATGAAAAAG
ATCCAAGAACTTTTGAAGGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAATTTGATTTGGGTCAAGACGTTATAGATT
TTACTGGTCATGCTCTTGCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAAACCATTAATAGAATTAAACTTTACAGTG
AATCTTTGGCAAGATATGGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTGCCCCAAGGATTTGCAAGGCTAAGTGCTA
TTTATGGAGGTACCTATATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAAGTAATTGGTGTAAAATCTGAAGGAGAAA
TTGCTCGCTGTAAGCAGCTCATCTGTGACCCCAGCTACGTAAAAGATCGGGTAGAAAAAGTGGGCCAGGTGATCAGAGTTATTTGCATCC
TCAGCCACCCCATCAAGAACACCAATGATGCCAACTCCTGCCAGATCATTATTCCACAGAACCAAGTCAATCGAAAGTCAGATATCTACG
TCTGCATGATCTCCTTTGCGCACAATGTAGCAGCACAAGGGAAGTACATTGCTATAGTTAGTACAACTGTGGAAACCAAGGAGCCTGAGA
AGGAAATCAGACCAGCTTTGGAGCTCTTGGAACCAATTGAACAGAAATTTGTTAGCATCAGTGACCTCCTGGTACCAAAAGACTTGGGAA
CAGAAAGCCAGATCTTTATTTCCCGCACATATGATGCCACCACTCATTTTGAGACAACGTGTGATGACATTAAAAACATCTATAAGAGGA
TGACAGGATCAGAGTTTGACTTTGAGGAAATGAAGCGCAAGAAGAATGACATCTATGGGGAAGACTAACAGCAGTACATGTTATTATGTA
ATTAGGACACATTTAAAATTTGGCAAATAATGCATATAATGAAATCAATATTGTAAGGCCTGCTTTTGTAATGAAAATGGAGAGAATGAA
GAGCGCTGTGCCAGTAAATACTCCCCTTCACCTTTCTAATTATTAACTTGTTTTCATGGAGTGGCTATTCAGCATTGGCAGTTACCACAT
TCTGTTCAATTTAACCAAACTGGCTTTTTTTTTTTCTAGTGAAGTTAAACAAACATTGGGATACCGACACAGACAACTTGAGACAGTTTT
TTTAATCTTTTAATCAGTGTAGCTATGTGCTGCTGCTGCTCAAGAGCTGGATCCATACAGGTTGTGTGTCATCTGTCCTCTTGAGGTTCA
GGAGATTCTAAATTGAATATTCCACGGTTTGGGACAGCATCCGGAAGTTTTCCCTATGACTTTATATTTTGTATTATGTCAAATGTTATG
GCAGGGCCCAAATAGCATAGCCACAAGTTTGGTTTATGTGGGCATAAAATTCTAACCAAACCCCAGACATAGGGAGTCATTTGGAGAAAG
CCTGTATGTGGTGTTTTAACCTAATAAAGTTGATGAGAGAGAAGGGGAGAGGAAGCGAACATAAAGCGGGTCAAGTGTAGTGCATCTTTT
GTATCTCAGGCGTGGCTTCTTCAGTGGACCAAGCTGCAATGCAGTATTGACTTGACAGAGCCTCTACTTCTGTCTCAAAATGGCTCCAAA

>447_447_10_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376160_GDI2_chr10_5842668_ENST00000380191_length(amino acids)=525AA_BP=95
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSI
NHISQECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYL
DFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALA
LYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQL
ICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPAL

--------------------------------------------------------------
>447_447_11_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376166_GDI2_chr10_5842668_ENST00000380191_length(transcript)=2484nt_BP=408nt
ACAATACCAGGCGGGAGGGCGGGTAGGCGGTTTGTATCCGGGCTGTGAGGTGCTCGGAGCCTCGGCGGACCTTGCTGCCTCTGTCTCTTT
AACGCGAGAGGAAGCGATGCAGAGGGGTGGAAAATGGCAGAGCTGCAGATGTTACTAGAGGAGGAGATCCCGTCTGGCAAGAGGGCGCTG
ATCGAGAGTTACCAGAACCTGACTCGGGTGGCAGACTACTGTGAAAACAACTACATACAGGCTACAGACAAGAGAAAAGCTTTAGAGGAG
ACCAAAGCCTATACAACCCAATCTCTAGCTAGTGTTGCTTATCAAATAAATGCATTGGCCAACAATGTACTCCAGTTGCTGGATATCCAA
GCCTCTCAGCTTCGGAGAATGGAGTCTTCCATCAATCATATCTCACAGGAATGTATCCTGTCAGGTATAATGTCAGTGAATGGCAAGAAA
GTTCTTCATATGGATCGAAACCCTTACTACGGAGGAGAGAGTGCATCTATAACACCATTGGAAGATTTATACAAAAGATTTAAAATACCA
GGATCACCACCCGAGTCAATGGGGAGAGGAAGAGACTGGAATGTTGACTTGATTCCCAAGTTCCTTATGGCTAATGGTCAGCTGGTTAAG
ATGCTGCTTTATACAGAGGTAACTCGCTATCTGGATTTTAAAGTGACTGAAGGGAGCTTTGTCTATAAGGGTGGAAAAATCTACAAGGTT
CCTTCCACTGAAGCAGAAGCCCTGGCATCTAGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTAGTGTATGTTGCCAAC
TTCGATGAAAAAGATCCAAGAACTTTTGAAGGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAATTTGATTTGGGTCAA
GACGTTATAGATTTTACTGGTCATGCTCTTGCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAAACCATTAATAGAATT
AAACTTTACAGTGAATCTTTGGCAAGATATGGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTGCCCCAAGGATTTGCA
AGGCTAAGTGCTATTTATGGAGGTACCTATATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAAGTAATTGGTGTAAAA
TCTGAAGGAGAAATTGCTCGCTGTAAGCAGCTCATCTGTGACCCCAGCTACGTAAAAGATCGGGTAGAAAAAGTGGGCCAGGTGATCAGA
GTTATTTGCATCCTCAGCCACCCCATCAAGAACACCAATGATGCCAACTCCTGCCAGATCATTATTCCACAGAACCAAGTCAATCGAAAG
TCAGATATCTACGTCTGCATGATCTCCTTTGCGCACAATGTAGCAGCACAAGGGAAGTACATTGCTATAGTTAGTACAACTGTGGAAACC
AAGGAGCCTGAGAAGGAAATCAGACCAGCTTTGGAGCTCTTGGAACCAATTGAACAGAAATTTGTTAGCATCAGTGACCTCCTGGTACCA
AAAGACTTGGGAACAGAAAGCCAGATCTTTATTTCCCGCACATATGATGCCACCACTCATTTTGAGACAACGTGTGATGACATTAAAAAC
ATCTATAAGAGGATGACAGGATCAGAGTTTGACTTTGAGGAAATGAAGCGCAAGAAGAATGACATCTATGGGGAAGACTAACAGCAGTAC
ATGTTATTATGTAATTAGGACACATTTAAAATTTGGCAAATAATGCATATAATGAAATCAATATTGTAAGGCCTGCTTTTGTAATGAAAA
TGGAGAGAATGAAGAGCGCTGTGCCAGTAAATACTCCCCTTCACCTTTCTAATTATTAACTTGTTTTCATGGAGTGGCTATTCAGCATTG
GCAGTTACCACATTCTGTTCAATTTAACCAAACTGGCTTTTTTTTTTTCTAGTGAAGTTAAACAAACATTGGGATACCGACACAGACAAC
TTGAGACAGTTTTTTTAATCTTTTAATCAGTGTAGCTATGTGCTGCTGCTGCTCAAGAGCTGGATCCATACAGGTTGTGTGTCATCTGTC
CTCTTGAGGTTCAGGAGATTCTAAATTGAATATTCCACGGTTTGGGACAGCATCCGGAAGTTTTCCCTATGACTTTATATTTTGTATTAT
GTCAAATGTTATGGCAGGGCCCAAATAGCATAGCCACAAGTTTGGTTTATGTGGGCATAAAATTCTAACCAAACCCCAGACATAGGGAGT
CATTTGGAGAAAGCCTGTATGTGGTGTTTTAACCTAATAAAGTTGATGAGAGAGAAGGGGAGAGGAAGCGAACATAAAGCGGGTCAAGTG
TAGTGCATCTTTTGTATCTCAGGCGTGGCTTCTTCAGTGGACCAAGCTGCAATGCAGTATTGACTTGACAGAGCCTCTACTTCTGTCTCA

>447_447_11_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376166_GDI2_chr10_5842668_ENST00000380191_length(amino acids)=525AA_BP=95
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSI
NHISQECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYL
DFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALA
LYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQL
ICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPAL

--------------------------------------------------------------
>447_447_12_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376170_GDI2_chr10_5842668_ENST00000380191_length(transcript)=2390nt_BP=314nt
CGAGAGGAAGCGATGCAGAGGGGTGGAAAATGGCAGAGCTGCAGATGTTACTAGAGGAGGAGATCCCGTCTGGCAAGAGGGCGCTGATCG
AGAGTTACCAGAACCTGACTCGGGTGGCAGACTACTGTGAAAACAACTACATACAGGCTACAGACAAGAGAAAAGCTTTAGAGGAGACCA
AAGCCTATACAACCCAATCTCTAGCTAGTGTTGCTTATCAAATAAATGCATTGGCCAACAATGTACTCCAGTTGCTGGATATCCAAGCCT
CTCAGCTTCGGAGAATGGAGTCTTCCATCAATCATATCTCACAGGAATGTATCCTGTCAGGTATAATGTCAGTGAATGGCAAGAAAGTTC
TTCATATGGATCGAAACCCTTACTACGGAGGAGAGAGTGCATCTATAACACCATTGGAAGATTTATACAAAAGATTTAAAATACCAGGAT
CACCACCCGAGTCAATGGGGAGAGGAAGAGACTGGAATGTTGACTTGATTCCCAAGTTCCTTATGGCTAATGGTCAGCTGGTTAAGATGC
TGCTTTATACAGAGGTAACTCGCTATCTGGATTTTAAAGTGACTGAAGGGAGCTTTGTCTATAAGGGTGGAAAAATCTACAAGGTTCCTT
CCACTGAAGCAGAAGCCCTGGCATCTAGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTAGTGTATGTTGCCAACTTCG
ATGAAAAAGATCCAAGAACTTTTGAAGGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAATTTGATTTGGGTCAAGACG
TTATAGATTTTACTGGTCATGCTCTTGCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAAACCATTAATAGAATTAAAC
TTTACAGTGAATCTTTGGCAAGATATGGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTGCCCCAAGGATTTGCAAGGC
TAAGTGCTATTTATGGAGGTACCTATATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAAGTAATTGGTGTAAAATCTG
AAGGAGAAATTGCTCGCTGTAAGCAGCTCATCTGTGACCCCAGCTACGTAAAAGATCGGGTAGAAAAAGTGGGCCAGGTGATCAGAGTTA
TTTGCATCCTCAGCCACCCCATCAAGAACACCAATGATGCCAACTCCTGCCAGATCATTATTCCACAGAACCAAGTCAATCGAAAGTCAG
ATATCTACGTCTGCATGATCTCCTTTGCGCACAATGTAGCAGCACAAGGGAAGTACATTGCTATAGTTAGTACAACTGTGGAAACCAAGG
AGCCTGAGAAGGAAATCAGACCAGCTTTGGAGCTCTTGGAACCAATTGAACAGAAATTTGTTAGCATCAGTGACCTCCTGGTACCAAAAG
ACTTGGGAACAGAAAGCCAGATCTTTATTTCCCGCACATATGATGCCACCACTCATTTTGAGACAACGTGTGATGACATTAAAAACATCT
ATAAGAGGATGACAGGATCAGAGTTTGACTTTGAGGAAATGAAGCGCAAGAAGAATGACATCTATGGGGAAGACTAACAGCAGTACATGT
TATTATGTAATTAGGACACATTTAAAATTTGGCAAATAATGCATATAATGAAATCAATATTGTAAGGCCTGCTTTTGTAATGAAAATGGA
GAGAATGAAGAGCGCTGTGCCAGTAAATACTCCCCTTCACCTTTCTAATTATTAACTTGTTTTCATGGAGTGGCTATTCAGCATTGGCAG
TTACCACATTCTGTTCAATTTAACCAAACTGGCTTTTTTTTTTTCTAGTGAAGTTAAACAAACATTGGGATACCGACACAGACAACTTGA
GACAGTTTTTTTAATCTTTTAATCAGTGTAGCTATGTGCTGCTGCTGCTCAAGAGCTGGATCCATACAGGTTGTGTGTCATCTGTCCTCT
TGAGGTTCAGGAGATTCTAAATTGAATATTCCACGGTTTGGGACAGCATCCGGAAGTTTTCCCTATGACTTTATATTTTGTATTATGTCA
AATGTTATGGCAGGGCCCAAATAGCATAGCCACAAGTTTGGTTTATGTGGGCATAAAATTCTAACCAAACCCCAGACATAGGGAGTCATT
TGGAGAAAGCCTGTATGTGGTGTTTTAACCTAATAAAGTTGATGAGAGAGAAGGGGAGAGGAAGCGAACATAAAGCGGGTCAAGTGTAGT
GCATCTTTTGTATCTCAGGCGTGGCTTCTTCAGTGGACCAAGCTGCAATGCAGTATTGACTTGACAGAGCCTCTACTTCTGTCTCAAAAT

>447_447_12_ABI1-GDI2_ABI1_chr10_27112067_ENST00000376170_GDI2_chr10_5842668_ENST00000380191_length(amino acids)=525AA_BP=95
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSI
NHISQECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYL
DFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALA
LYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQL
ICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPAL

--------------------------------------------------------------
>447_447_13_ABI1-GDI2_ABI1_chr10_27112067_ENST00000490841_GDI2_chr10_5842668_ENST00000380191_length(transcript)=2585nt_BP=509nt
GAGAAATAAACGCTCGCGAGAGAACGAGGTTCAGGCGGCTGCACGAAGGGGGTGGAGGGGGGCTGGAGAGAGTGAGGAGGAAGGGGAGGA
GGTGCCGTCCCACAATACCAGGCGGGAGGGCGGGTAGGCGGTTTGTATCCGGGCTGTGAGGTGCTCGGAGCCTCGGCGGACCTTGCTGCC
TCTGTCTCTTTAACGCGAGAGGAAGCGATGCAGAGGGGTGGAAAATGGCAGAGCTGCAGATGTTACTAGAGGAGGAGATCCCGTCTGGCA
AGAGGGCGCTGATCGAGAGTTACCAGAACCTGACTCGGGTGGCAGACTACTGTGAAAACAACTACATACAGGCTACAGACAAGAGAAAAG
CTTTAGAGGAGACCAAAGCCTATACAACCCAATCTCTAGCTAGTGTTGCTTATCAAATAAATGCATTGGCCAACAATGTACTCCAGTTGC
TGGATATCCAAGCCTCTCAGCTTCGGAGAATGGAGTCTTCCATCAATCATATCTCACAGGAATGTATCCTGTCAGGTATAATGTCAGTGA
ATGGCAAGAAAGTTCTTCATATGGATCGAAACCCTTACTACGGAGGAGAGAGTGCATCTATAACACCATTGGAAGATTTATACAAAAGAT
TTAAAATACCAGGATCACCACCCGAGTCAATGGGGAGAGGAAGAGACTGGAATGTTGACTTGATTCCCAAGTTCCTTATGGCTAATGGTC
AGCTGGTTAAGATGCTGCTTTATACAGAGGTAACTCGCTATCTGGATTTTAAAGTGACTGAAGGGAGCTTTGTCTATAAGGGTGGAAAAA
TCTACAAGGTTCCTTCCACTGAAGCAGAAGCCCTGGCATCTAGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTAGTGT
ATGTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTGAAGGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAATTTG
ATTTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTCTTGCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAAACCA
TTAATAGAATTAAACTTTACAGTGAATCTTTGGCAAGATATGGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTGCCCC
AAGGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCTATATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAAGTAA
TTGGTGTAAAATCTGAAGGAGAAATTGCTCGCTGTAAGCAGCTCATCTGTGACCCCAGCTACGTAAAAGATCGGGTAGAAAAAGTGGGCC
AGGTGATCAGAGTTATTTGCATCCTCAGCCACCCCATCAAGAACACCAATGATGCCAACTCCTGCCAGATCATTATTCCACAGAACCAAG
TCAATCGAAAGTCAGATATCTACGTCTGCATGATCTCCTTTGCGCACAATGTAGCAGCACAAGGGAAGTACATTGCTATAGTTAGTACAA
CTGTGGAAACCAAGGAGCCTGAGAAGGAAATCAGACCAGCTTTGGAGCTCTTGGAACCAATTGAACAGAAATTTGTTAGCATCAGTGACC
TCCTGGTACCAAAAGACTTGGGAACAGAAAGCCAGATCTTTATTTCCCGCACATATGATGCCACCACTCATTTTGAGACAACGTGTGATG
ACATTAAAAACATCTATAAGAGGATGACAGGATCAGAGTTTGACTTTGAGGAAATGAAGCGCAAGAAGAATGACATCTATGGGGAAGACT
AACAGCAGTACATGTTATTATGTAATTAGGACACATTTAAAATTTGGCAAATAATGCATATAATGAAATCAATATTGTAAGGCCTGCTTT
TGTAATGAAAATGGAGAGAATGAAGAGCGCTGTGCCAGTAAATACTCCCCTTCACCTTTCTAATTATTAACTTGTTTTCATGGAGTGGCT
ATTCAGCATTGGCAGTTACCACATTCTGTTCAATTTAACCAAACTGGCTTTTTTTTTTTCTAGTGAAGTTAAACAAACATTGGGATACCG
ACACAGACAACTTGAGACAGTTTTTTTAATCTTTTAATCAGTGTAGCTATGTGCTGCTGCTGCTCAAGAGCTGGATCCATACAGGTTGTG
TGTCATCTGTCCTCTTGAGGTTCAGGAGATTCTAAATTGAATATTCCACGGTTTGGGACAGCATCCGGAAGTTTTCCCTATGACTTTATA
TTTTGTATTATGTCAAATGTTATGGCAGGGCCCAAATAGCATAGCCACAAGTTTGGTTTATGTGGGCATAAAATTCTAACCAAACCCCAG
ACATAGGGAGTCATTTGGAGAAAGCCTGTATGTGGTGTTTTAACCTAATAAAGTTGATGAGAGAGAAGGGGAGAGGAAGCGAACATAAAG
CGGGTCAAGTGTAGTGCATCTTTTGTATCTCAGGCGTGGCTTCTTCAGTGGACCAAGCTGCAATGCAGTATTGACTTGACAGAGCCTCTA

>447_447_13_ABI1-GDI2_ABI1_chr10_27112067_ENST00000490841_GDI2_chr10_5842668_ENST00000380191_length(amino acids)=525AA_BP=95
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSI
NHISQECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYL
DFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALA
LYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQL
ICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPAL

--------------------------------------------------------------
>447_447_14_ABI1-GDI2_ABI1_chr10_27112067_ENST00000536334_GDI2_chr10_5842668_ENST00000380191_length(transcript)=2585nt_BP=509nt
GAGAAATAAACGCTCGCGAGAGAACGAGGTTCAGGCGGCTGCACGAAGGGGGTGGAGGGGGGCTGGAGAGAGTGAGGAGGAAGGGGAGGA
GGTGCCGTCCCACAATACCAGGCGGGAGGGCGGGTAGGCGGTTTGTATCCGGGCTGTGAGGTGCTCGGAGCCTCGGCGGACCTTGCTGCC
TCTGTCTCTTTAACGCGAGAGGAAGCGATGCAGAGGGGTGGAAAATGGCAGAGCTGCAGATGTTACTAGAGGAGGAGATCCCGTCTGGCA
AGAGGGCGCTGATCGAGAGTTACCAGAACCTGACTCGGGTGGCAGACTACTGTGAAAACAACTACATACAGGCTACAGACAAGAGAAAAG
CTTTAGAGGAGACCAAAGCCTATACAACCCAATCTCTAGCTAGTGTTGCTTATCAAATAAATGCATTGGCCAACAATGTACTCCAGTTGC
TGGATATCCAAGCCTCTCAGCTTCGGAGAATGGAGTCTTCCATCAATCATATCTCACAGGAATGTATCCTGTCAGGTATAATGTCAGTGA
ATGGCAAGAAAGTTCTTCATATGGATCGAAACCCTTACTACGGAGGAGAGAGTGCATCTATAACACCATTGGAAGATTTATACAAAAGAT
TTAAAATACCAGGATCACCACCCGAGTCAATGGGGAGAGGAAGAGACTGGAATGTTGACTTGATTCCCAAGTTCCTTATGGCTAATGGTC
AGCTGGTTAAGATGCTGCTTTATACAGAGGTAACTCGCTATCTGGATTTTAAAGTGACTGAAGGGAGCTTTGTCTATAAGGGTGGAAAAA
TCTACAAGGTTCCTTCCACTGAAGCAGAAGCCCTGGCATCTAGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTAGTGT
ATGTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTGAAGGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAATTTG
ATTTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTCTTGCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAAACCA
TTAATAGAATTAAACTTTACAGTGAATCTTTGGCAAGATATGGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTGCCCC
AAGGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCTATATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAAGTAA
TTGGTGTAAAATCTGAAGGAGAAATTGCTCGCTGTAAGCAGCTCATCTGTGACCCCAGCTACGTAAAAGATCGGGTAGAAAAAGTGGGCC
AGGTGATCAGAGTTATTTGCATCCTCAGCCACCCCATCAAGAACACCAATGATGCCAACTCCTGCCAGATCATTATTCCACAGAACCAAG
TCAATCGAAAGTCAGATATCTACGTCTGCATGATCTCCTTTGCGCACAATGTAGCAGCACAAGGGAAGTACATTGCTATAGTTAGTACAA
CTGTGGAAACCAAGGAGCCTGAGAAGGAAATCAGACCAGCTTTGGAGCTCTTGGAACCAATTGAACAGAAATTTGTTAGCATCAGTGACC
TCCTGGTACCAAAAGACTTGGGAACAGAAAGCCAGATCTTTATTTCCCGCACATATGATGCCACCACTCATTTTGAGACAACGTGTGATG
ACATTAAAAACATCTATAAGAGGATGACAGGATCAGAGTTTGACTTTGAGGAAATGAAGCGCAAGAAGAATGACATCTATGGGGAAGACT
AACAGCAGTACATGTTATTATGTAATTAGGACACATTTAAAATTTGGCAAATAATGCATATAATGAAATCAATATTGTAAGGCCTGCTTT
TGTAATGAAAATGGAGAGAATGAAGAGCGCTGTGCCAGTAAATACTCCCCTTCACCTTTCTAATTATTAACTTGTTTTCATGGAGTGGCT
ATTCAGCATTGGCAGTTACCACATTCTGTTCAATTTAACCAAACTGGCTTTTTTTTTTTCTAGTGAAGTTAAACAAACATTGGGATACCG
ACACAGACAACTTGAGACAGTTTTTTTAATCTTTTAATCAGTGTAGCTATGTGCTGCTGCTGCTCAAGAGCTGGATCCATACAGGTTGTG
TGTCATCTGTCCTCTTGAGGTTCAGGAGATTCTAAATTGAATATTCCACGGTTTGGGACAGCATCCGGAAGTTTTCCCTATGACTTTATA
TTTTGTATTATGTCAAATGTTATGGCAGGGCCCAAATAGCATAGCCACAAGTTTGGTTTATGTGGGCATAAAATTCTAACCAAACCCCAG
ACATAGGGAGTCATTTGGAGAAAGCCTGTATGTGGTGTTTTAACCTAATAAAGTTGATGAGAGAGAAGGGGAGAGGAAGCGAACATAAAG
CGGGTCAAGTGTAGTGCATCTTTTGTATCTCAGGCGTGGCTTCTTCAGTGGACCAAGCTGCAATGCAGTATTGACTTGACAGAGCCTCTA

>447_447_14_ABI1-GDI2_ABI1_chr10_27112067_ENST00000536334_GDI2_chr10_5842668_ENST00000380191_length(amino acids)=525AA_BP=95
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSI
NHISQECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYL
DFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALA
LYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQL
ICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPAL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ABI1-GDI2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ABI1-GDI2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ABI1-GDI2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneABI1C0019193Hepatitis, Toxic1CTD_human
HgeneABI1C0860207Drug-Induced Liver Disease1CTD_human
HgeneABI1C1262760Hepatitis, Drug-Induced1CTD_human
HgeneABI1C3658290Drug-Induced Acute Liver Injury1CTD_human
HgeneABI1C4277682Chemical and Drug Induced Liver Injury1CTD_human
HgeneABI1C4279912Chemically-Induced Liver Toxicity1CTD_human
TgeneC0279626Squamous cell carcinoma of esophagus1CTD_human