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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:CDH3-C16orf70 (FusionGDB2 ID:HG1001TG80262)

Fusion Gene Summary for CDH3-C16orf70

Fusion gene summary

Fusion gene information	Fusion gene name: CDH3-C16orf70
	Fusion gene ID: hg1001tg80262
		Hgene	Tgene
	Gene symbol	CDH3	C16orf70
	Gene ID	1001	80262
	Gene name	cadherin 3	chromosome 16 open reading frame 70
	Synonyms	CDHP\|HJMD\|PCAD	C16orf6\|LIN10\|lin-10
	Cytomap	('CDH3')('C16orf70') 16q22.1	16q22.1
	Type of gene	protein-coding	protein-coding
	Description	cadherin-3cadherin 3, type 1, P-cadherin (placental)calcium-dependent adhesion protein, placental	UPF0183 protein C16orf70lin-10 homolog
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000264012, ENST00000429102, ENST00000569117, ENST00000581171,
Fusion gene scores	* DoF score	12 X 8 X 6=576	7 X 7 X 6=294
	# samples	15	8
	** MAII score	log2(15/576*10)=-1.94110631094643 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(8/294*10)=-1.877744249949 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: CDH3 [Title/Abstract] AND C16orf70 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	CDH3(68679653)-C16orf70(67154015), # samples:3
Anticipated loss of major functional domain due to fusion event.	CDH3-C16orf70 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CDH3-C16orf70 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across CDH3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across C16orf70 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	ESCA	TCGA-L5-A4OS-01A	CDH3	chr16	68679653	-	C16orf70	chr16	67154015	+
ChimerDB4	ESCA	TCGA-L5-A4OS-01A	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+
ChimerDB4	ESCA	TCGA-L5-A4OS	CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+
ChimerDB4	ESCA	TCGA-L5-A4OS	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+

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Fusion Gene ORF analysis for CDH3-C16orf70

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-3UTR	ENST00000264012	ENST00000569683	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+
5CDS-3UTR	ENST00000264012	ENST00000569683	CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+
5CDS-3UTR	ENST00000429102	ENST00000569683	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+
5CDS-3UTR	ENST00000429102	ENST00000569683	CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+
In-frame	ENST00000264012	ENST00000219139	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+
In-frame	ENST00000264012	ENST00000219139	CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+
In-frame	ENST00000264012	ENST00000569600	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+
In-frame	ENST00000264012	ENST00000569600	CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+
In-frame	ENST00000429102	ENST00000219139	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+
In-frame	ENST00000429102	ENST00000219139	CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+
In-frame	ENST00000429102	ENST00000569600	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+
In-frame	ENST00000429102	ENST00000569600	CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+
intron-3CDS	ENST00000569117	ENST00000219139	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+
intron-3CDS	ENST00000569117	ENST00000219139	CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+
intron-3CDS	ENST00000569117	ENST00000569600	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+
intron-3CDS	ENST00000569117	ENST00000569600	CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+
intron-3CDS	ENST00000581171	ENST00000219139	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+
intron-3CDS	ENST00000581171	ENST00000219139	CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+
intron-3CDS	ENST00000581171	ENST00000569600	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+
intron-3CDS	ENST00000581171	ENST00000569600	CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+
intron-3UTR	ENST00000569117	ENST00000569683	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+
intron-3UTR	ENST00000569117	ENST00000569683	CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+
intron-3UTR	ENST00000581171	ENST00000569683	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+
intron-3UTR	ENST00000581171	ENST00000569683	CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000264012	CDH3	chr16	68679653	+	ENST00000569600	C16orf70	chr16	67154015	+	1909	704	346	1908	521
ENST00000264012	CDH3	chr16	68679653	+	ENST00000219139	C16orf70	chr16	67154015	+	3317	704	346	1908	520
ENST00000429102	CDH3	chr16	68679653	+	ENST00000569600	C16orf70	chr16	67154015	+	1752	547	189	1751	520
ENST00000429102	CDH3	chr16	68679653	+	ENST00000219139	C16orf70	chr16	67154015	+	3160	547	189	1751	520
ENST00000264012	CDH3	chr16	68679653	+	ENST00000569600	C16orf70	chr16	67154014	+	1909	704	346	1908	521
ENST00000264012	CDH3	chr16	68679653	+	ENST00000219139	C16orf70	chr16	67154014	+	3317	704	346	1908	520
ENST00000429102	CDH3	chr16	68679653	+	ENST00000569600	C16orf70	chr16	67154014	+	1752	547	189	1751	520
ENST00000429102	CDH3	chr16	68679653	+	ENST00000219139	C16orf70	chr16	67154014	+	3160	547	189	1751	520

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000264012	ENST00000569600	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+	0.001606517	0.9983935
ENST00000264012	ENST00000219139	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+	0.000601087	0.99939895
ENST00000429102	ENST00000569600	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+	0.00190712	0.99809283
ENST00000429102	ENST00000219139	CDH3	chr16	68679653	+	C16orf70	chr16	67154015	+	0.000638943	0.9993611
ENST00000264012	ENST00000569600	CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+	0.001606517	0.9983935
ENST00000264012	ENST00000219139	CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+	0.000601087	0.99939895
ENST00000429102	ENST00000569600	CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+	0.00190712	0.99809283
ENST00000429102	ENST00000219139	CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+	0.000638943	0.9993611

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Fusion Genomic Features for CDH3-C16orf70

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+	1.29E-05	0.9999871
CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+	1.29E-05	0.9999871
CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+	1.29E-05	0.9999871
CDH3	chr16	68679653	+	C16orf70	chr16	67154014	+	1.29E-05	0.9999871

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CDH3-C16orf70

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:68679653/chr16:67154015)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000264012

785_800

830.0

Compositional bias

Note=Ser-rich

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000429102

785_800

785.0

Compositional bias

Note=Ser-rich

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000264012

785_800

830.0

Compositional bias

Note=Ser-rich

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000429102

785_800

785.0

Compositional bias

Note=Ser-rich

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000264012

108_215

830.0

Domain

Cadherin 1

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000264012

216_328

830.0

Domain

Cadherin 2

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000264012

329_440

830.0

Domain

Cadherin 3

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000264012

441_546

830.0

Domain

Cadherin 4

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000264012

547_650

830.0

Domain

Cadherin 5

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000429102

108_215

785.0

Domain

Cadherin 1

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000429102

216_328

785.0

Domain

Cadherin 2

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000429102

329_440

785.0

Domain

Cadherin 3

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000429102

441_546

785.0

Domain

Cadherin 4

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000429102

547_650

785.0

Domain

Cadherin 5

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000264012

108_215

830.0

Domain

Cadherin 1

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000264012

216_328

830.0

Domain

Cadherin 2

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000264012

329_440

830.0

Domain

Cadherin 3

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000264012

441_546

830.0

Domain

Cadherin 4

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000264012

547_650

830.0

Domain

Cadherin 5

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000429102

108_215

785.0

Domain

Cadherin 1

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000429102

216_328

785.0

Domain

Cadherin 2

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000429102

329_440

785.0

Domain

Cadherin 3

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000429102

441_546

785.0

Domain

Cadherin 4

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000429102

547_650

785.0

Domain

Cadherin 5

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000264012

108_654

830.0

Topological domain

Extracellular

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000264012

678_829

830.0

Topological domain

Cytoplasmic

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000429102

108_654

785.0

Topological domain

Extracellular

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000429102

678_829

785.0

Topological domain

Cytoplasmic

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000264012

108_654

830.0

Topological domain

Extracellular

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000264012

678_829

830.0

Topological domain

Cytoplasmic

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000429102

108_654

785.0

Topological domain

Extracellular

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000429102

678_829

785.0

Topological domain

Cytoplasmic

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000264012

655_677

830.0

Transmembrane

Helical

Hgene

CDH3

chr16:68679653

chr16:67154014

ENST00000429102

655_677

785.0

Transmembrane

Helical

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000264012

655_677

830.0

Transmembrane

Helical

Hgene

CDH3

chr16:68679653

chr16:67154015

ENST00000429102

655_677

785.0

Transmembrane

Helical

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Fusion Gene Sequence for CDH3-C16orf70

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>15071_15071_1_CDH3-C16orf70_CDH3_chr16_68679653_ENST00000264012_C16orf70_chr16_67154014_ENST00000219139_length(transcript)=3317nt_BP=704nt
GGCTGGCACGGGAGGTGGAGAAAGAGGCTTGGGCGGCCCCGCTGTAGCCGCGTGTGGGAGGACGCACGGGCCTGCTTCAAAGCTTTGGGA
TAACAGCGCCTCCGGGGGATAATGAATGCGGAGCCTCCGTTTTCAGTCGACTTCAGATGTGTCTCCACTTTTTTCCGCTGTAGCCGCAAG
GCAAGGAAACATTTCTCTTCCCGTACTGAGGAGGCTGAGGAGTGCACTGGGTGTTCTTTTCTCCTCTAACCCAGAACTGCGAGACAGAGG
CTGAGTCCCTGTAAAGAACAGCTCCAGAAAAGCCAGGAGAGCGCAGGAGGGCATCCGGGAGGCCAGGAGGGGTTCGCTGGGGCCTCAACC
GCACCCACATCGGTCCCACCTGCGAGGGGGCGGGACCTCGTGGCGCTGGACCAATCAGCACCCACCTGCGCTCACCTGGCCTCCTCCCGC
TGGCTCCCGGGGGCTGCGGTGCTCAAAGGGGCAAGAGCTGAGCGGAACACCGGCCCGCCGTCGCGGCAGCTGCTTCACCCCTCTCTCTGC
AGCCATGGGGCTCCCTCGTGGACCTCTCGCGTCTCTCCTCCTTCTCCAGGTTTGCTGGCTGCAGTGCGCGGCCTCCGAGCCGTGCCGGGC
GGTCTTCAGGGAGGCTGAAGTGACCTTGGAGGCGGGAGGCGCGGAGCAGGAGCCCGGCCAGGCGCTGGGGAAAGGAATGCCTCTGGCTCA
GGCAGTAGCCATTCTTCAGAAGCACTGTCGCATCATCAAAAACGTCCAGGTTCTCTACAGTGAACAGTCTCCTCTAAGCCATGACCTCAT
TCTTAACCTGACTCAGGACGGGATCAAACTAATGTTTGATGCTTTCAATCAGAGACTTAAGGTGATCGAAGTATGTGATTTGACTAAAGT
AAAGTTAAAATATTGTGGCGTGCATTTTAATTCTCAGGCCATAGCTCCTACCATTGAACAGATTGACCAGTCTTTTGGCGCAACCCATCC
TGGAGTGTACAACTCCGCTGAGCAGCTCTTCCATCTCAACTTCAGAGGACTGTCTTTCTCTTTTCAGTTAGACTCATGGACTGAGGCTCC
AAAGTATGAGCCCAATTTTGCCCATGGCCTGGCTTCTCTCCAGATACCCCATGGAGCAACTGTAAAACGAATGTACATCTACAGTGGCAA
CAGCCTGCAGGATACCAAGGCTCCCATGATGCCTCTGAGCTGTTTCCTGGGCAATGTCTATGCTGAGAGTGTAGATGTTCTTCGAGATGG
AACTGGACCTGCAGGTTTACGACTTCGCCTACTTGCTGCAGGTTGTGGACCTGGCCTATTAGCAGATGCCAAGATGCGGGTATTTGAACG
TTCAGTGTATTTTGGTGATTCCTGCCAAGATGTTCTTAGCATGCTTGGCTCTCCACACAAAGTCTTCTATAAATCAGAAGACAAGATGAA
AATTCATTCTCCTTCCCCTCATAAACAAGTTCCATCGAAGTGTAATGACTACTTTTTTAACTACTTCACTCTTGGAGTGGACATCCTCTT
TGATGCGAATACACACAAAGTGAAGAAGTTTGTTCTACACACCAATTACCCTGGGCATTATAATTTCAACATTTATCATCGCTGTGAGTT
CAAGATCCCACTAGCCATAAAGAAAGAAAACGCAGATGGTCAGACAGAAACATGCACGACCTACAGCAAGTGGGACAACATCCAGGAGCT
CCTGGGCCACCCTGTGGAGAAGCCTGTTGTCCTGCACAGGTCTTCCTCCCCAAACAACACCAACCCATTTGGTTCCACATTCTGCTTTGG
TCTTCAGCGAATGATCTTTGAGGTCATGCAGAACAACCACATTGCCTCGGTGACCCTGTATGGCCCCCCCAGGCCTGGTAGCCACCTGAG
AACAGCGGAACTCCCCTAGGGACACCACCACCCATGCCCCTCTGTCCCGTGGAACTGTGCATCACATCCTGCTCAGTGGGCCTCTGTACC
ACCCTGTGGGTTTTCTTGGACACCTGGCCAGTGCTGAAGGGCTGTTGTGATGTTCTGAGGTTGGGCTCAGGCTGGGTGCTCTGCCATGGG
CTGAGTGGCCCAGATATTCTTCTGTCCATCTTTGGCCTGCTGGTGCCAGCAGGGGACACAGACTGCAAAGAGAAGCACAAAGTTTGAGCC
TTGATTCCTGGACCCAGGAGCTCTCAACTAACAAGGAGGCAGGAGAGGTCAACCCTTGTCCCATGCACATTGGGAAGACTTGGGGCTCTT
TCTGTGACTGAGGACACAGGCACCCAGGATAAGGACAAGGTCCTGCCTTTGGCTCCACATTGCCACATGACCCTTAAGGCAAGCAGGTAG
CGTGTCCATAGTACTTGGTTGCGACATTTGCACTACATCCACTTTAGTTACTTGATGAGCTGGCTGTGGCCAGGGTGGCCCACCTGCCCT
TCCCTGTTCCTTTCTTGCACGCGCTCCCTGCCTGGGCACACCAAACTGGTTGAAACACAGCTTTCTACCATCCAGGTACATGCCCAGGCC
TGGTTCTCACCCCTGTTGGAGTCAGCTTTCAAGATTGCCTGTGCCCCTGCTCTGCCCCATCCTGGCTGGCAGGGCTGCATGTTTCCATCC
TGTTTGCCTCTTTTATTTAATGCCAAAGTTTTAGCCAAAGACATCTTCCTACTTTTGTTGTGTTTCAGCATTCTGTTCTGCACTGTGGGC
TGGCTCTCTGCCCCAACCCTGGGCACTGGCCCCTGGCTGGGCCATTTCATGGCTCAAAGCCTCTGGGGGCTCAAGGAAGGCTGGGCTGCT
CAGTCCCTTCATGGGTCTTGCTAATGGAAAGTAGCATATATGTGCTTTAAAAATATTAATCCTTTTGAAAAGAACTGAGAAGAAAAATGT
ATAATTTTATCCCATTTTTAATATTTTGGTCTAGCAACTTGTGATACATAGATGACAATTTTGTGAGTTTTTCAAATGTGTGTACAGATT
TTTGTAAATATGACTCTTTTGTAATTAACTCATGTACAGCCTCATCCTGTATAGTTTAATGATGAATGTGCAGGGGACCTGTCTCAGGCT
CCTATATGGTTCCTGGGCCTTATAGCCAGGTTTGTGTGGCGCTCCCGACTTTTGTGACTGACTGGTGTCTTCCCATTTGGACTGTGGCCT
GGCCAGAGCCCCTTGCATATCCCCACTGTCAGGGGCAGCCAGGACTGTTCCCATCCTCCTGGAATGGGGGAACCTTCCTTATCCCCTGCC
CACATCCCCTCTCCAATAAAGCACCTGTGCCCTCAGCAATGGCCTGCCATGTGCTGTTGCTGGGATGTTTGTATTAA

>15071_15071_1_CDH3-C16orf70_CDH3_chr16_68679653_ENST00000264012_C16orf70_chr16_67154014_ENST00000219139_length(amino acids)=520AA_BP=119
MGPQPHPHRSHLRGGGTSWRWTNQHPPALTWPPPAGSRGLRCSKGQELSGTPARRRGSCFTPLSAAMGLPRGPLASLLLLQVCWLQCAAS
EPCRAVFREAEVTLEAGGAEQEPGQALGKGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVC
DLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMY
IYSGNSLQDTKAPMMPLSCFLGNVYAESVDVLRDGTGPAGLRLRLLAAGCGPGLLADAKMRVFERSVYFGDSCQDVLSMLGSPHKVFYKS
EDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENADGQTETCTTYSKWD
NIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGSHLRTAELP

--------------------------------------------------------------
>15071_15071_2_CDH3-C16orf70_CDH3_chr16_68679653_ENST00000264012_C16orf70_chr16_67154014_ENST00000569600_length(transcript)=1909nt_BP=704nt
GGCTGGCACGGGAGGTGGAGAAAGAGGCTTGGGCGGCCCCGCTGTAGCCGCGTGTGGGAGGACGCACGGGCCTGCTTCAAAGCTTTGGGA
TAACAGCGCCTCCGGGGGATAATGAATGCGGAGCCTCCGTTTTCAGTCGACTTCAGATGTGTCTCCACTTTTTTCCGCTGTAGCCGCAAG
GCAAGGAAACATTTCTCTTCCCGTACTGAGGAGGCTGAGGAGTGCACTGGGTGTTCTTTTCTCCTCTAACCCAGAACTGCGAGACAGAGG
CTGAGTCCCTGTAAAGAACAGCTCCAGAAAAGCCAGGAGAGCGCAGGAGGGCATCCGGGAGGCCAGGAGGGGTTCGCTGGGGCCTCAACC
GCACCCACATCGGTCCCACCTGCGAGGGGGCGGGACCTCGTGGCGCTGGACCAATCAGCACCCACCTGCGCTCACCTGGCCTCCTCCCGC
TGGCTCCCGGGGGCTGCGGTGCTCAAAGGGGCAAGAGCTGAGCGGAACACCGGCCCGCCGTCGCGGCAGCTGCTTCACCCCTCTCTCTGC
AGCCATGGGGCTCCCTCGTGGACCTCTCGCGTCTCTCCTCCTTCTCCAGGTTTGCTGGCTGCAGTGCGCGGCCTCCGAGCCGTGCCGGGC
GGTCTTCAGGGAGGCTGAAGTGACCTTGGAGGCGGGAGGCGCGGAGCAGGAGCCCGGCCAGGCGCTGGGGAAAGGAATGCCTCTGGCTCA
GGCAGTAGCCATTCTTCAGAAGCACTGTCGCATCATCAAAAACGTCCAGGTTCTCTACAGTGAACAGTCTCCTCTAAGCCATGACCTCAT
TCTTAACCTGACTCAGGACGGGATCAAACTAATGTTTGATGCTTTCAATCAGAGACTTAAGGTGATCGAAGTATGTGATTTGACTAAAGT
AAAGTTAAAATATTGTGGCGTGCATTTTAATTCTCAGGCCATAGCTCCTACCATTGAACAGATTGACCAGTCTTTTGGCGCAACCCATCC
TGGAGTGTACAACTCCGCTGAGCAGCTCTTCCATCTCAACTTCAGAGGACTGTCTTTCTCTTTTCAGTTAGACTCATGGACTGAGGCTCC
AAAGTATGAGCCCAATTTTGCCCATGGCCTGGCTTCTCTCCAGATACCCCATGGAGCAACTGTAAAACGAATGTACATCTACAGTGGCAA
CAGCCTGCAGGATACCAAGGCTCCCATGATGCCTCTGAGCTGTTTCCTGGGCAATGTCTATGCTGAGAGTGTAGATGTTCTTCGAGATGG
AACTGGACCTGCAGGTTTACGACTTCGCCTACTTGCTGCAGGTTGTGGACCTGGCCTATTAGCAGATGCCAAGATGCGGGTATTTGAACG
TTCAGTGTATTTTGGTGATTCCTGCCAAGATGTTCTTAGCATGCTTGGCTCTCCACACAAAGTCTTCTATAAATCAGAAGACAAGATGAA
AATTCATTCTCCTTCCCCTCATAAACAAGTTCCATCGAAGTGTAATGACTACTTTTTTAACTACTTCACTCTTGGAGTGGACATCCTCTT
TGATGCGAATACACACAAAGTGAAGAAGTTTGTTCTACACACCAATTACCCTGGGCATTATAATTTCAACATTTATCATCGCTGTGAGTT
CAAGATCCCACTAGCCATAAAGAAAGAAAACGCAGATGGTCAGACAGAAACATGCACGACCTACAGCAAGTGGGACAACATCCAGGAGCT
CCTGGGCCACCCTGTGGAGAAGCCTGTTGTCCTGCACAGGTCTTCCTCCCCAAACAACACCAACCCATTTGGTTCCACATTCTGCTTTGG
TCTTCAGCGAATGATCTTTGAGGTCATGCAGAACAACCACATTGCCTCGGTGACCCTGTATGGCCCCCCCAGGCCTGGTAGCCACCTGAG
AACAGCGGAACTCCCCTAG

>15071_15071_2_CDH3-C16orf70_CDH3_chr16_68679653_ENST00000264012_C16orf70_chr16_67154014_ENST00000569600_length(amino acids)=521AA_BP=119
MGPQPHPHRSHLRGGGTSWRWTNQHPPALTWPPPAGSRGLRCSKGQELSGTPARRRGSCFTPLSAAMGLPRGPLASLLLLQVCWLQCAAS
EPCRAVFREAEVTLEAGGAEQEPGQALGKGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVC
DLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMY
IYSGNSLQDTKAPMMPLSCFLGNVYAESVDVLRDGTGPAGLRLRLLAAGCGPGLLADAKMRVFERSVYFGDSCQDVLSMLGSPHKVFYKS
EDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENADGQTETCTTYSKWD
NIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGSHLRTAELPX

--------------------------------------------------------------
>15071_15071_3_CDH3-C16orf70_CDH3_chr16_68679653_ENST00000264012_C16orf70_chr16_67154015_ENST00000219139_length(transcript)=3317nt_BP=704nt
GGCTGGCACGGGAGGTGGAGAAAGAGGCTTGGGCGGCCCCGCTGTAGCCGCGTGTGGGAGGACGCACGGGCCTGCTTCAAAGCTTTGGGA
TAACAGCGCCTCCGGGGGATAATGAATGCGGAGCCTCCGTTTTCAGTCGACTTCAGATGTGTCTCCACTTTTTTCCGCTGTAGCCGCAAG
GCAAGGAAACATTTCTCTTCCCGTACTGAGGAGGCTGAGGAGTGCACTGGGTGTTCTTTTCTCCTCTAACCCAGAACTGCGAGACAGAGG
CTGAGTCCCTGTAAAGAACAGCTCCAGAAAAGCCAGGAGAGCGCAGGAGGGCATCCGGGAGGCCAGGAGGGGTTCGCTGGGGCCTCAACC
GCACCCACATCGGTCCCACCTGCGAGGGGGCGGGACCTCGTGGCGCTGGACCAATCAGCACCCACCTGCGCTCACCTGGCCTCCTCCCGC
TGGCTCCCGGGGGCTGCGGTGCTCAAAGGGGCAAGAGCTGAGCGGAACACCGGCCCGCCGTCGCGGCAGCTGCTTCACCCCTCTCTCTGC
AGCCATGGGGCTCCCTCGTGGACCTCTCGCGTCTCTCCTCCTTCTCCAGGTTTGCTGGCTGCAGTGCGCGGCCTCCGAGCCGTGCCGGGC
GGTCTTCAGGGAGGCTGAAGTGACCTTGGAGGCGGGAGGCGCGGAGCAGGAGCCCGGCCAGGCGCTGGGGAAAGGAATGCCTCTGGCTCA
GGCAGTAGCCATTCTTCAGAAGCACTGTCGCATCATCAAAAACGTCCAGGTTCTCTACAGTGAACAGTCTCCTCTAAGCCATGACCTCAT
TCTTAACCTGACTCAGGACGGGATCAAACTAATGTTTGATGCTTTCAATCAGAGACTTAAGGTGATCGAAGTATGTGATTTGACTAAAGT
AAAGTTAAAATATTGTGGCGTGCATTTTAATTCTCAGGCCATAGCTCCTACCATTGAACAGATTGACCAGTCTTTTGGCGCAACCCATCC
TGGAGTGTACAACTCCGCTGAGCAGCTCTTCCATCTCAACTTCAGAGGACTGTCTTTCTCTTTTCAGTTAGACTCATGGACTGAGGCTCC
AAAGTATGAGCCCAATTTTGCCCATGGCCTGGCTTCTCTCCAGATACCCCATGGAGCAACTGTAAAACGAATGTACATCTACAGTGGCAA
CAGCCTGCAGGATACCAAGGCTCCCATGATGCCTCTGAGCTGTTTCCTGGGCAATGTCTATGCTGAGAGTGTAGATGTTCTTCGAGATGG
AACTGGACCTGCAGGTTTACGACTTCGCCTACTTGCTGCAGGTTGTGGACCTGGCCTATTAGCAGATGCCAAGATGCGGGTATTTGAACG
TTCAGTGTATTTTGGTGATTCCTGCCAAGATGTTCTTAGCATGCTTGGCTCTCCACACAAAGTCTTCTATAAATCAGAAGACAAGATGAA
AATTCATTCTCCTTCCCCTCATAAACAAGTTCCATCGAAGTGTAATGACTACTTTTTTAACTACTTCACTCTTGGAGTGGACATCCTCTT
TGATGCGAATACACACAAAGTGAAGAAGTTTGTTCTACACACCAATTACCCTGGGCATTATAATTTCAACATTTATCATCGCTGTGAGTT
CAAGATCCCACTAGCCATAAAGAAAGAAAACGCAGATGGTCAGACAGAAACATGCACGACCTACAGCAAGTGGGACAACATCCAGGAGCT
CCTGGGCCACCCTGTGGAGAAGCCTGTTGTCCTGCACAGGTCTTCCTCCCCAAACAACACCAACCCATTTGGTTCCACATTCTGCTTTGG
TCTTCAGCGAATGATCTTTGAGGTCATGCAGAACAACCACATTGCCTCGGTGACCCTGTATGGCCCCCCCAGGCCTGGTAGCCACCTGAG
AACAGCGGAACTCCCCTAGGGACACCACCACCCATGCCCCTCTGTCCCGTGGAACTGTGCATCACATCCTGCTCAGTGGGCCTCTGTACC
ACCCTGTGGGTTTTCTTGGACACCTGGCCAGTGCTGAAGGGCTGTTGTGATGTTCTGAGGTTGGGCTCAGGCTGGGTGCTCTGCCATGGG
CTGAGTGGCCCAGATATTCTTCTGTCCATCTTTGGCCTGCTGGTGCCAGCAGGGGACACAGACTGCAAAGAGAAGCACAAAGTTTGAGCC
TTGATTCCTGGACCCAGGAGCTCTCAACTAACAAGGAGGCAGGAGAGGTCAACCCTTGTCCCATGCACATTGGGAAGACTTGGGGCTCTT
TCTGTGACTGAGGACACAGGCACCCAGGATAAGGACAAGGTCCTGCCTTTGGCTCCACATTGCCACATGACCCTTAAGGCAAGCAGGTAG
CGTGTCCATAGTACTTGGTTGCGACATTTGCACTACATCCACTTTAGTTACTTGATGAGCTGGCTGTGGCCAGGGTGGCCCACCTGCCCT
TCCCTGTTCCTTTCTTGCACGCGCTCCCTGCCTGGGCACACCAAACTGGTTGAAACACAGCTTTCTACCATCCAGGTACATGCCCAGGCC
TGGTTCTCACCCCTGTTGGAGTCAGCTTTCAAGATTGCCTGTGCCCCTGCTCTGCCCCATCCTGGCTGGCAGGGCTGCATGTTTCCATCC
TGTTTGCCTCTTTTATTTAATGCCAAAGTTTTAGCCAAAGACATCTTCCTACTTTTGTTGTGTTTCAGCATTCTGTTCTGCACTGTGGGC
TGGCTCTCTGCCCCAACCCTGGGCACTGGCCCCTGGCTGGGCCATTTCATGGCTCAAAGCCTCTGGGGGCTCAAGGAAGGCTGGGCTGCT
CAGTCCCTTCATGGGTCTTGCTAATGGAAAGTAGCATATATGTGCTTTAAAAATATTAATCCTTTTGAAAAGAACTGAGAAGAAAAATGT
ATAATTTTATCCCATTTTTAATATTTTGGTCTAGCAACTTGTGATACATAGATGACAATTTTGTGAGTTTTTCAAATGTGTGTACAGATT
TTTGTAAATATGACTCTTTTGTAATTAACTCATGTACAGCCTCATCCTGTATAGTTTAATGATGAATGTGCAGGGGACCTGTCTCAGGCT
CCTATATGGTTCCTGGGCCTTATAGCCAGGTTTGTGTGGCGCTCCCGACTTTTGTGACTGACTGGTGTCTTCCCATTTGGACTGTGGCCT
GGCCAGAGCCCCTTGCATATCCCCACTGTCAGGGGCAGCCAGGACTGTTCCCATCCTCCTGGAATGGGGGAACCTTCCTTATCCCCTGCC
CACATCCCCTCTCCAATAAAGCACCTGTGCCCTCAGCAATGGCCTGCCATGTGCTGTTGCTGGGATGTTTGTATTAA

>15071_15071_3_CDH3-C16orf70_CDH3_chr16_68679653_ENST00000264012_C16orf70_chr16_67154015_ENST00000219139_length(amino acids)=520AA_BP=119
MGPQPHPHRSHLRGGGTSWRWTNQHPPALTWPPPAGSRGLRCSKGQELSGTPARRRGSCFTPLSAAMGLPRGPLASLLLLQVCWLQCAAS
EPCRAVFREAEVTLEAGGAEQEPGQALGKGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVC
DLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMY
IYSGNSLQDTKAPMMPLSCFLGNVYAESVDVLRDGTGPAGLRLRLLAAGCGPGLLADAKMRVFERSVYFGDSCQDVLSMLGSPHKVFYKS
EDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENADGQTETCTTYSKWD
NIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGSHLRTAELP

--------------------------------------------------------------
>15071_15071_4_CDH3-C16orf70_CDH3_chr16_68679653_ENST00000264012_C16orf70_chr16_67154015_ENST00000569600_length(transcript)=1909nt_BP=704nt
GGCTGGCACGGGAGGTGGAGAAAGAGGCTTGGGCGGCCCCGCTGTAGCCGCGTGTGGGAGGACGCACGGGCCTGCTTCAAAGCTTTGGGA
TAACAGCGCCTCCGGGGGATAATGAATGCGGAGCCTCCGTTTTCAGTCGACTTCAGATGTGTCTCCACTTTTTTCCGCTGTAGCCGCAAG
GCAAGGAAACATTTCTCTTCCCGTACTGAGGAGGCTGAGGAGTGCACTGGGTGTTCTTTTCTCCTCTAACCCAGAACTGCGAGACAGAGG
CTGAGTCCCTGTAAAGAACAGCTCCAGAAAAGCCAGGAGAGCGCAGGAGGGCATCCGGGAGGCCAGGAGGGGTTCGCTGGGGCCTCAACC
GCACCCACATCGGTCCCACCTGCGAGGGGGCGGGACCTCGTGGCGCTGGACCAATCAGCACCCACCTGCGCTCACCTGGCCTCCTCCCGC
TGGCTCCCGGGGGCTGCGGTGCTCAAAGGGGCAAGAGCTGAGCGGAACACCGGCCCGCCGTCGCGGCAGCTGCTTCACCCCTCTCTCTGC
AGCCATGGGGCTCCCTCGTGGACCTCTCGCGTCTCTCCTCCTTCTCCAGGTTTGCTGGCTGCAGTGCGCGGCCTCCGAGCCGTGCCGGGC
GGTCTTCAGGGAGGCTGAAGTGACCTTGGAGGCGGGAGGCGCGGAGCAGGAGCCCGGCCAGGCGCTGGGGAAAGGAATGCCTCTGGCTCA
GGCAGTAGCCATTCTTCAGAAGCACTGTCGCATCATCAAAAACGTCCAGGTTCTCTACAGTGAACAGTCTCCTCTAAGCCATGACCTCAT
TCTTAACCTGACTCAGGACGGGATCAAACTAATGTTTGATGCTTTCAATCAGAGACTTAAGGTGATCGAAGTATGTGATTTGACTAAAGT
AAAGTTAAAATATTGTGGCGTGCATTTTAATTCTCAGGCCATAGCTCCTACCATTGAACAGATTGACCAGTCTTTTGGCGCAACCCATCC
TGGAGTGTACAACTCCGCTGAGCAGCTCTTCCATCTCAACTTCAGAGGACTGTCTTTCTCTTTTCAGTTAGACTCATGGACTGAGGCTCC
AAAGTATGAGCCCAATTTTGCCCATGGCCTGGCTTCTCTCCAGATACCCCATGGAGCAACTGTAAAACGAATGTACATCTACAGTGGCAA
CAGCCTGCAGGATACCAAGGCTCCCATGATGCCTCTGAGCTGTTTCCTGGGCAATGTCTATGCTGAGAGTGTAGATGTTCTTCGAGATGG
AACTGGACCTGCAGGTTTACGACTTCGCCTACTTGCTGCAGGTTGTGGACCTGGCCTATTAGCAGATGCCAAGATGCGGGTATTTGAACG
TTCAGTGTATTTTGGTGATTCCTGCCAAGATGTTCTTAGCATGCTTGGCTCTCCACACAAAGTCTTCTATAAATCAGAAGACAAGATGAA
AATTCATTCTCCTTCCCCTCATAAACAAGTTCCATCGAAGTGTAATGACTACTTTTTTAACTACTTCACTCTTGGAGTGGACATCCTCTT
TGATGCGAATACACACAAAGTGAAGAAGTTTGTTCTACACACCAATTACCCTGGGCATTATAATTTCAACATTTATCATCGCTGTGAGTT
CAAGATCCCACTAGCCATAAAGAAAGAAAACGCAGATGGTCAGACAGAAACATGCACGACCTACAGCAAGTGGGACAACATCCAGGAGCT
CCTGGGCCACCCTGTGGAGAAGCCTGTTGTCCTGCACAGGTCTTCCTCCCCAAACAACACCAACCCATTTGGTTCCACATTCTGCTTTGG
TCTTCAGCGAATGATCTTTGAGGTCATGCAGAACAACCACATTGCCTCGGTGACCCTGTATGGCCCCCCCAGGCCTGGTAGCCACCTGAG
AACAGCGGAACTCCCCTAG

>15071_15071_4_CDH3-C16orf70_CDH3_chr16_68679653_ENST00000264012_C16orf70_chr16_67154015_ENST00000569600_length(amino acids)=521AA_BP=119
MGPQPHPHRSHLRGGGTSWRWTNQHPPALTWPPPAGSRGLRCSKGQELSGTPARRRGSCFTPLSAAMGLPRGPLASLLLLQVCWLQCAAS
EPCRAVFREAEVTLEAGGAEQEPGQALGKGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVC
DLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMY
IYSGNSLQDTKAPMMPLSCFLGNVYAESVDVLRDGTGPAGLRLRLLAAGCGPGLLADAKMRVFERSVYFGDSCQDVLSMLGSPHKVFYKS
EDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENADGQTETCTTYSKWD
NIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGSHLRTAELPX

--------------------------------------------------------------
>15071_15071_5_CDH3-C16orf70_CDH3_chr16_68679653_ENST00000429102_C16orf70_chr16_67154014_ENST00000219139_length(transcript)=3160nt_BP=547nt
CTTTTTTCCGCTGTAGCCGCAAGGCAAGGAAACATTTCTCTTCCCGTACTGAGGAGGCTGAGGAGTGCACTGGGTGTTCTTTTCTCCTCT
AACCCAGAACTGCGAGACAGAGGCTGAGTCCCTGTAAAGAACAGCTCCAGAAAAGCCAGGAGAGCGCAGGAGGGCATCCGGGAGGCCAGG
AGGGGTTCGCTGGGGCCTCAACCGCACCCACATCGGTCCCACCTGCGAGGGGGCGGGACCTCGTGGCGCTGGACCAATCAGCACCCACCT
GCGCTCACCTGGCCTCCTCCCGCTGGCTCCCGGGGGCTGCGGTGCTCAAAGGGGCAAGAGCTGAGCGGAACACCGGCCCGCCGTCGCGGC
AGCTGCTTCACCCCTCTCTCTGCAGCCATGGGGCTCCCTCGTGGACCTCTCGCGTCTCTCCTCCTTCTCCAGGTTTGCTGGCTGCAGTGC
GCGGCCTCCGAGCCGTGCCGGGCGGTCTTCAGGGAGGCTGAAGTGACCTTGGAGGCGGGAGGCGCGGAGCAGGAGCCCGGCCAGGCGCTG
GGGAAAGGAATGCCTCTGGCTCAGGCAGTAGCCATTCTTCAGAAGCACTGTCGCATCATCAAAAACGTCCAGGTTCTCTACAGTGAACAG
TCTCCTCTAAGCCATGACCTCATTCTTAACCTGACTCAGGACGGGATCAAACTAATGTTTGATGCTTTCAATCAGAGACTTAAGGTGATC
GAAGTATGTGATTTGACTAAAGTAAAGTTAAAATATTGTGGCGTGCATTTTAATTCTCAGGCCATAGCTCCTACCATTGAACAGATTGAC
CAGTCTTTTGGCGCAACCCATCCTGGAGTGTACAACTCCGCTGAGCAGCTCTTCCATCTCAACTTCAGAGGACTGTCTTTCTCTTTTCAG
TTAGACTCATGGACTGAGGCTCCAAAGTATGAGCCCAATTTTGCCCATGGCCTGGCTTCTCTCCAGATACCCCATGGAGCAACTGTAAAA
CGAATGTACATCTACAGTGGCAACAGCCTGCAGGATACCAAGGCTCCCATGATGCCTCTGAGCTGTTTCCTGGGCAATGTCTATGCTGAG
AGTGTAGATGTTCTTCGAGATGGAACTGGACCTGCAGGTTTACGACTTCGCCTACTTGCTGCAGGTTGTGGACCTGGCCTATTAGCAGAT
GCCAAGATGCGGGTATTTGAACGTTCAGTGTATTTTGGTGATTCCTGCCAAGATGTTCTTAGCATGCTTGGCTCTCCACACAAAGTCTTC
TATAAATCAGAAGACAAGATGAAAATTCATTCTCCTTCCCCTCATAAACAAGTTCCATCGAAGTGTAATGACTACTTTTTTAACTACTTC
ACTCTTGGAGTGGACATCCTCTTTGATGCGAATACACACAAAGTGAAGAAGTTTGTTCTACACACCAATTACCCTGGGCATTATAATTTC
AACATTTATCATCGCTGTGAGTTCAAGATCCCACTAGCCATAAAGAAAGAAAACGCAGATGGTCAGACAGAAACATGCACGACCTACAGC
AAGTGGGACAACATCCAGGAGCTCCTGGGCCACCCTGTGGAGAAGCCTGTTGTCCTGCACAGGTCTTCCTCCCCAAACAACACCAACCCA
TTTGGTTCCACATTCTGCTTTGGTCTTCAGCGAATGATCTTTGAGGTCATGCAGAACAACCACATTGCCTCGGTGACCCTGTATGGCCCC
CCCAGGCCTGGTAGCCACCTGAGAACAGCGGAACTCCCCTAGGGACACCACCACCCATGCCCCTCTGTCCCGTGGAACTGTGCATCACAT
CCTGCTCAGTGGGCCTCTGTACCACCCTGTGGGTTTTCTTGGACACCTGGCCAGTGCTGAAGGGCTGTTGTGATGTTCTGAGGTTGGGCT
CAGGCTGGGTGCTCTGCCATGGGCTGAGTGGCCCAGATATTCTTCTGTCCATCTTTGGCCTGCTGGTGCCAGCAGGGGACACAGACTGCA
AAGAGAAGCACAAAGTTTGAGCCTTGATTCCTGGACCCAGGAGCTCTCAACTAACAAGGAGGCAGGAGAGGTCAACCCTTGTCCCATGCA
CATTGGGAAGACTTGGGGCTCTTTCTGTGACTGAGGACACAGGCACCCAGGATAAGGACAAGGTCCTGCCTTTGGCTCCACATTGCCACA
TGACCCTTAAGGCAAGCAGGTAGCGTGTCCATAGTACTTGGTTGCGACATTTGCACTACATCCACTTTAGTTACTTGATGAGCTGGCTGT
GGCCAGGGTGGCCCACCTGCCCTTCCCTGTTCCTTTCTTGCACGCGCTCCCTGCCTGGGCACACCAAACTGGTTGAAACACAGCTTTCTA
CCATCCAGGTACATGCCCAGGCCTGGTTCTCACCCCTGTTGGAGTCAGCTTTCAAGATTGCCTGTGCCCCTGCTCTGCCCCATCCTGGCT
GGCAGGGCTGCATGTTTCCATCCTGTTTGCCTCTTTTATTTAATGCCAAAGTTTTAGCCAAAGACATCTTCCTACTTTTGTTGTGTTTCA
GCATTCTGTTCTGCACTGTGGGCTGGCTCTCTGCCCCAACCCTGGGCACTGGCCCCTGGCTGGGCCATTTCATGGCTCAAAGCCTCTGGG
GGCTCAAGGAAGGCTGGGCTGCTCAGTCCCTTCATGGGTCTTGCTAATGGAAAGTAGCATATATGTGCTTTAAAAATATTAATCCTTTTG
AAAAGAACTGAGAAGAAAAATGTATAATTTTATCCCATTTTTAATATTTTGGTCTAGCAACTTGTGATACATAGATGACAATTTTGTGAG
TTTTTCAAATGTGTGTACAGATTTTTGTAAATATGACTCTTTTGTAATTAACTCATGTACAGCCTCATCCTGTATAGTTTAATGATGAAT
GTGCAGGGGACCTGTCTCAGGCTCCTATATGGTTCCTGGGCCTTATAGCCAGGTTTGTGTGGCGCTCCCGACTTTTGTGACTGACTGGTG
TCTTCCCATTTGGACTGTGGCCTGGCCAGAGCCCCTTGCATATCCCCACTGTCAGGGGCAGCCAGGACTGTTCCCATCCTCCTGGAATGG
GGGAACCTTCCTTATCCCCTGCCCACATCCCCTCTCCAATAAAGCACCTGTGCCCTCAGCAATGGCCTGCCATGTGCTGTTGCTGGGATG
TTTGTATTAA

>15071_15071_5_CDH3-C16orf70_CDH3_chr16_68679653_ENST00000429102_C16orf70_chr16_67154014_ENST00000219139_length(amino acids)=520AA_BP=119
MGPQPHPHRSHLRGGGTSWRWTNQHPPALTWPPPAGSRGLRCSKGQELSGTPARRRGSCFTPLSAAMGLPRGPLASLLLLQVCWLQCAAS
EPCRAVFREAEVTLEAGGAEQEPGQALGKGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVC
DLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMY
IYSGNSLQDTKAPMMPLSCFLGNVYAESVDVLRDGTGPAGLRLRLLAAGCGPGLLADAKMRVFERSVYFGDSCQDVLSMLGSPHKVFYKS
EDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENADGQTETCTTYSKWD
NIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGSHLRTAELP

--------------------------------------------------------------
>15071_15071_6_CDH3-C16orf70_CDH3_chr16_68679653_ENST00000429102_C16orf70_chr16_67154014_ENST00000569600_length(transcript)=1752nt_BP=547nt
CTTTTTTCCGCTGTAGCCGCAAGGCAAGGAAACATTTCTCTTCCCGTACTGAGGAGGCTGAGGAGTGCACTGGGTGTTCTTTTCTCCTCT
AACCCAGAACTGCGAGACAGAGGCTGAGTCCCTGTAAAGAACAGCTCCAGAAAAGCCAGGAGAGCGCAGGAGGGCATCCGGGAGGCCAGG
AGGGGTTCGCTGGGGCCTCAACCGCACCCACATCGGTCCCACCTGCGAGGGGGCGGGACCTCGTGGCGCTGGACCAATCAGCACCCACCT
GCGCTCACCTGGCCTCCTCCCGCTGGCTCCCGGGGGCTGCGGTGCTCAAAGGGGCAAGAGCTGAGCGGAACACCGGCCCGCCGTCGCGGC
AGCTGCTTCACCCCTCTCTCTGCAGCCATGGGGCTCCCTCGTGGACCTCTCGCGTCTCTCCTCCTTCTCCAGGTTTGCTGGCTGCAGTGC
GCGGCCTCCGAGCCGTGCCGGGCGGTCTTCAGGGAGGCTGAAGTGACCTTGGAGGCGGGAGGCGCGGAGCAGGAGCCCGGCCAGGCGCTG
GGGAAAGGAATGCCTCTGGCTCAGGCAGTAGCCATTCTTCAGAAGCACTGTCGCATCATCAAAAACGTCCAGGTTCTCTACAGTGAACAG
TCTCCTCTAAGCCATGACCTCATTCTTAACCTGACTCAGGACGGGATCAAACTAATGTTTGATGCTTTCAATCAGAGACTTAAGGTGATC
GAAGTATGTGATTTGACTAAAGTAAAGTTAAAATATTGTGGCGTGCATTTTAATTCTCAGGCCATAGCTCCTACCATTGAACAGATTGAC
CAGTCTTTTGGCGCAACCCATCCTGGAGTGTACAACTCCGCTGAGCAGCTCTTCCATCTCAACTTCAGAGGACTGTCTTTCTCTTTTCAG
TTAGACTCATGGACTGAGGCTCCAAAGTATGAGCCCAATTTTGCCCATGGCCTGGCTTCTCTCCAGATACCCCATGGAGCAACTGTAAAA
CGAATGTACATCTACAGTGGCAACAGCCTGCAGGATACCAAGGCTCCCATGATGCCTCTGAGCTGTTTCCTGGGCAATGTCTATGCTGAG
AGTGTAGATGTTCTTCGAGATGGAACTGGACCTGCAGGTTTACGACTTCGCCTACTTGCTGCAGGTTGTGGACCTGGCCTATTAGCAGAT
GCCAAGATGCGGGTATTTGAACGTTCAGTGTATTTTGGTGATTCCTGCCAAGATGTTCTTAGCATGCTTGGCTCTCCACACAAAGTCTTC
TATAAATCAGAAGACAAGATGAAAATTCATTCTCCTTCCCCTCATAAACAAGTTCCATCGAAGTGTAATGACTACTTTTTTAACTACTTC
ACTCTTGGAGTGGACATCCTCTTTGATGCGAATACACACAAAGTGAAGAAGTTTGTTCTACACACCAATTACCCTGGGCATTATAATTTC
AACATTTATCATCGCTGTGAGTTCAAGATCCCACTAGCCATAAAGAAAGAAAACGCAGATGGTCAGACAGAAACATGCACGACCTACAGC
AAGTGGGACAACATCCAGGAGCTCCTGGGCCACCCTGTGGAGAAGCCTGTTGTCCTGCACAGGTCTTCCTCCCCAAACAACACCAACCCA
TTTGGTTCCACATTCTGCTTTGGTCTTCAGCGAATGATCTTTGAGGTCATGCAGAACAACCACATTGCCTCGGTGACCCTGTATGGCCCC
CCCAGGCCTGGTAGCCACCTGAGAACAGCGGAACTCCCCTAG

>15071_15071_6_CDH3-C16orf70_CDH3_chr16_68679653_ENST00000429102_C16orf70_chr16_67154014_ENST00000569600_length(amino acids)=520AA_BP=119
MGPQPHPHRSHLRGGGTSWRWTNQHPPALTWPPPAGSRGLRCSKGQELSGTPARRRGSCFTPLSAAMGLPRGPLASLLLLQVCWLQCAAS
EPCRAVFREAEVTLEAGGAEQEPGQALGKGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVC
DLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMY
IYSGNSLQDTKAPMMPLSCFLGNVYAESVDVLRDGTGPAGLRLRLLAAGCGPGLLADAKMRVFERSVYFGDSCQDVLSMLGSPHKVFYKS
EDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENADGQTETCTTYSKWD
NIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGSHLRTAELP

--------------------------------------------------------------
>15071_15071_7_CDH3-C16orf70_CDH3_chr16_68679653_ENST00000429102_C16orf70_chr16_67154015_ENST00000219139_length(transcript)=3160nt_BP=547nt
CTTTTTTCCGCTGTAGCCGCAAGGCAAGGAAACATTTCTCTTCCCGTACTGAGGAGGCTGAGGAGTGCACTGGGTGTTCTTTTCTCCTCT
AACCCAGAACTGCGAGACAGAGGCTGAGTCCCTGTAAAGAACAGCTCCAGAAAAGCCAGGAGAGCGCAGGAGGGCATCCGGGAGGCCAGG
AGGGGTTCGCTGGGGCCTCAACCGCACCCACATCGGTCCCACCTGCGAGGGGGCGGGACCTCGTGGCGCTGGACCAATCAGCACCCACCT
GCGCTCACCTGGCCTCCTCCCGCTGGCTCCCGGGGGCTGCGGTGCTCAAAGGGGCAAGAGCTGAGCGGAACACCGGCCCGCCGTCGCGGC
AGCTGCTTCACCCCTCTCTCTGCAGCCATGGGGCTCCCTCGTGGACCTCTCGCGTCTCTCCTCCTTCTCCAGGTTTGCTGGCTGCAGTGC
GCGGCCTCCGAGCCGTGCCGGGCGGTCTTCAGGGAGGCTGAAGTGACCTTGGAGGCGGGAGGCGCGGAGCAGGAGCCCGGCCAGGCGCTG
GGGAAAGGAATGCCTCTGGCTCAGGCAGTAGCCATTCTTCAGAAGCACTGTCGCATCATCAAAAACGTCCAGGTTCTCTACAGTGAACAG
TCTCCTCTAAGCCATGACCTCATTCTTAACCTGACTCAGGACGGGATCAAACTAATGTTTGATGCTTTCAATCAGAGACTTAAGGTGATC
GAAGTATGTGATTTGACTAAAGTAAAGTTAAAATATTGTGGCGTGCATTTTAATTCTCAGGCCATAGCTCCTACCATTGAACAGATTGAC
CAGTCTTTTGGCGCAACCCATCCTGGAGTGTACAACTCCGCTGAGCAGCTCTTCCATCTCAACTTCAGAGGACTGTCTTTCTCTTTTCAG
TTAGACTCATGGACTGAGGCTCCAAAGTATGAGCCCAATTTTGCCCATGGCCTGGCTTCTCTCCAGATACCCCATGGAGCAACTGTAAAA
CGAATGTACATCTACAGTGGCAACAGCCTGCAGGATACCAAGGCTCCCATGATGCCTCTGAGCTGTTTCCTGGGCAATGTCTATGCTGAG
AGTGTAGATGTTCTTCGAGATGGAACTGGACCTGCAGGTTTACGACTTCGCCTACTTGCTGCAGGTTGTGGACCTGGCCTATTAGCAGAT
GCCAAGATGCGGGTATTTGAACGTTCAGTGTATTTTGGTGATTCCTGCCAAGATGTTCTTAGCATGCTTGGCTCTCCACACAAAGTCTTC
TATAAATCAGAAGACAAGATGAAAATTCATTCTCCTTCCCCTCATAAACAAGTTCCATCGAAGTGTAATGACTACTTTTTTAACTACTTC
ACTCTTGGAGTGGACATCCTCTTTGATGCGAATACACACAAAGTGAAGAAGTTTGTTCTACACACCAATTACCCTGGGCATTATAATTTC
AACATTTATCATCGCTGTGAGTTCAAGATCCCACTAGCCATAAAGAAAGAAAACGCAGATGGTCAGACAGAAACATGCACGACCTACAGC
AAGTGGGACAACATCCAGGAGCTCCTGGGCCACCCTGTGGAGAAGCCTGTTGTCCTGCACAGGTCTTCCTCCCCAAACAACACCAACCCA
TTTGGTTCCACATTCTGCTTTGGTCTTCAGCGAATGATCTTTGAGGTCATGCAGAACAACCACATTGCCTCGGTGACCCTGTATGGCCCC
CCCAGGCCTGGTAGCCACCTGAGAACAGCGGAACTCCCCTAGGGACACCACCACCCATGCCCCTCTGTCCCGTGGAACTGTGCATCACAT
CCTGCTCAGTGGGCCTCTGTACCACCCTGTGGGTTTTCTTGGACACCTGGCCAGTGCTGAAGGGCTGTTGTGATGTTCTGAGGTTGGGCT
CAGGCTGGGTGCTCTGCCATGGGCTGAGTGGCCCAGATATTCTTCTGTCCATCTTTGGCCTGCTGGTGCCAGCAGGGGACACAGACTGCA
AAGAGAAGCACAAAGTTTGAGCCTTGATTCCTGGACCCAGGAGCTCTCAACTAACAAGGAGGCAGGAGAGGTCAACCCTTGTCCCATGCA
CATTGGGAAGACTTGGGGCTCTTTCTGTGACTGAGGACACAGGCACCCAGGATAAGGACAAGGTCCTGCCTTTGGCTCCACATTGCCACA
TGACCCTTAAGGCAAGCAGGTAGCGTGTCCATAGTACTTGGTTGCGACATTTGCACTACATCCACTTTAGTTACTTGATGAGCTGGCTGT
GGCCAGGGTGGCCCACCTGCCCTTCCCTGTTCCTTTCTTGCACGCGCTCCCTGCCTGGGCACACCAAACTGGTTGAAACACAGCTTTCTA
CCATCCAGGTACATGCCCAGGCCTGGTTCTCACCCCTGTTGGAGTCAGCTTTCAAGATTGCCTGTGCCCCTGCTCTGCCCCATCCTGGCT
GGCAGGGCTGCATGTTTCCATCCTGTTTGCCTCTTTTATTTAATGCCAAAGTTTTAGCCAAAGACATCTTCCTACTTTTGTTGTGTTTCA
GCATTCTGTTCTGCACTGTGGGCTGGCTCTCTGCCCCAACCCTGGGCACTGGCCCCTGGCTGGGCCATTTCATGGCTCAAAGCCTCTGGG
GGCTCAAGGAAGGCTGGGCTGCTCAGTCCCTTCATGGGTCTTGCTAATGGAAAGTAGCATATATGTGCTTTAAAAATATTAATCCTTTTG
AAAAGAACTGAGAAGAAAAATGTATAATTTTATCCCATTTTTAATATTTTGGTCTAGCAACTTGTGATACATAGATGACAATTTTGTGAG
TTTTTCAAATGTGTGTACAGATTTTTGTAAATATGACTCTTTTGTAATTAACTCATGTACAGCCTCATCCTGTATAGTTTAATGATGAAT
GTGCAGGGGACCTGTCTCAGGCTCCTATATGGTTCCTGGGCCTTATAGCCAGGTTTGTGTGGCGCTCCCGACTTTTGTGACTGACTGGTG
TCTTCCCATTTGGACTGTGGCCTGGCCAGAGCCCCTTGCATATCCCCACTGTCAGGGGCAGCCAGGACTGTTCCCATCCTCCTGGAATGG
GGGAACCTTCCTTATCCCCTGCCCACATCCCCTCTCCAATAAAGCACCTGTGCCCTCAGCAATGGCCTGCCATGTGCTGTTGCTGGGATG
TTTGTATTAA

>15071_15071_7_CDH3-C16orf70_CDH3_chr16_68679653_ENST00000429102_C16orf70_chr16_67154015_ENST00000219139_length(amino acids)=520AA_BP=119
MGPQPHPHRSHLRGGGTSWRWTNQHPPALTWPPPAGSRGLRCSKGQELSGTPARRRGSCFTPLSAAMGLPRGPLASLLLLQVCWLQCAAS
EPCRAVFREAEVTLEAGGAEQEPGQALGKGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVC
DLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMY
IYSGNSLQDTKAPMMPLSCFLGNVYAESVDVLRDGTGPAGLRLRLLAAGCGPGLLADAKMRVFERSVYFGDSCQDVLSMLGSPHKVFYKS
EDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENADGQTETCTTYSKWD
NIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGSHLRTAELP

--------------------------------------------------------------
>15071_15071_8_CDH3-C16orf70_CDH3_chr16_68679653_ENST00000429102_C16orf70_chr16_67154015_ENST00000569600_length(transcript)=1752nt_BP=547nt
CTTTTTTCCGCTGTAGCCGCAAGGCAAGGAAACATTTCTCTTCCCGTACTGAGGAGGCTGAGGAGTGCACTGGGTGTTCTTTTCTCCTCT
AACCCAGAACTGCGAGACAGAGGCTGAGTCCCTGTAAAGAACAGCTCCAGAAAAGCCAGGAGAGCGCAGGAGGGCATCCGGGAGGCCAGG
AGGGGTTCGCTGGGGCCTCAACCGCACCCACATCGGTCCCACCTGCGAGGGGGCGGGACCTCGTGGCGCTGGACCAATCAGCACCCACCT
GCGCTCACCTGGCCTCCTCCCGCTGGCTCCCGGGGGCTGCGGTGCTCAAAGGGGCAAGAGCTGAGCGGAACACCGGCCCGCCGTCGCGGC
AGCTGCTTCACCCCTCTCTCTGCAGCCATGGGGCTCCCTCGTGGACCTCTCGCGTCTCTCCTCCTTCTCCAGGTTTGCTGGCTGCAGTGC
GCGGCCTCCGAGCCGTGCCGGGCGGTCTTCAGGGAGGCTGAAGTGACCTTGGAGGCGGGAGGCGCGGAGCAGGAGCCCGGCCAGGCGCTG
GGGAAAGGAATGCCTCTGGCTCAGGCAGTAGCCATTCTTCAGAAGCACTGTCGCATCATCAAAAACGTCCAGGTTCTCTACAGTGAACAG
TCTCCTCTAAGCCATGACCTCATTCTTAACCTGACTCAGGACGGGATCAAACTAATGTTTGATGCTTTCAATCAGAGACTTAAGGTGATC
GAAGTATGTGATTTGACTAAAGTAAAGTTAAAATATTGTGGCGTGCATTTTAATTCTCAGGCCATAGCTCCTACCATTGAACAGATTGAC
CAGTCTTTTGGCGCAACCCATCCTGGAGTGTACAACTCCGCTGAGCAGCTCTTCCATCTCAACTTCAGAGGACTGTCTTTCTCTTTTCAG
TTAGACTCATGGACTGAGGCTCCAAAGTATGAGCCCAATTTTGCCCATGGCCTGGCTTCTCTCCAGATACCCCATGGAGCAACTGTAAAA
CGAATGTACATCTACAGTGGCAACAGCCTGCAGGATACCAAGGCTCCCATGATGCCTCTGAGCTGTTTCCTGGGCAATGTCTATGCTGAG
AGTGTAGATGTTCTTCGAGATGGAACTGGACCTGCAGGTTTACGACTTCGCCTACTTGCTGCAGGTTGTGGACCTGGCCTATTAGCAGAT
GCCAAGATGCGGGTATTTGAACGTTCAGTGTATTTTGGTGATTCCTGCCAAGATGTTCTTAGCATGCTTGGCTCTCCACACAAAGTCTTC
TATAAATCAGAAGACAAGATGAAAATTCATTCTCCTTCCCCTCATAAACAAGTTCCATCGAAGTGTAATGACTACTTTTTTAACTACTTC
ACTCTTGGAGTGGACATCCTCTTTGATGCGAATACACACAAAGTGAAGAAGTTTGTTCTACACACCAATTACCCTGGGCATTATAATTTC
AACATTTATCATCGCTGTGAGTTCAAGATCCCACTAGCCATAAAGAAAGAAAACGCAGATGGTCAGACAGAAACATGCACGACCTACAGC
AAGTGGGACAACATCCAGGAGCTCCTGGGCCACCCTGTGGAGAAGCCTGTTGTCCTGCACAGGTCTTCCTCCCCAAACAACACCAACCCA
TTTGGTTCCACATTCTGCTTTGGTCTTCAGCGAATGATCTTTGAGGTCATGCAGAACAACCACATTGCCTCGGTGACCCTGTATGGCCCC
CCCAGGCCTGGTAGCCACCTGAGAACAGCGGAACTCCCCTAG

>15071_15071_8_CDH3-C16orf70_CDH3_chr16_68679653_ENST00000429102_C16orf70_chr16_67154015_ENST00000569600_length(amino acids)=520AA_BP=119
MGPQPHPHRSHLRGGGTSWRWTNQHPPALTWPPPAGSRGLRCSKGQELSGTPARRRGSCFTPLSAAMGLPRGPLASLLLLQVCWLQCAAS
EPCRAVFREAEVTLEAGGAEQEPGQALGKGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVC
DLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMY
IYSGNSLQDTKAPMMPLSCFLGNVYAESVDVLRDGTGPAGLRLRLLAAGCGPGLLADAKMRVFERSVYFGDSCQDVLSMLGSPHKVFYKS
EDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENADGQTETCTTYSKWD
NIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGSHLRTAELP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CDH3-C16orf70

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for CDH3-C16orf70

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for CDH3-C16orf70

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	CDH3	C1832162	HYPOTRICHOSIS, CONGENITAL, WITH JUVENILE MACULAR DYSTROPHY	3	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
Hgene	CDH3	C1857041	Ectodermal dysplasia, ectrodactyly, and macular dystrophy	3	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
Hgene	CDH3	C0009324	Ulcerative Colitis	1	CTD_human
Hgene	CDH3	C0010093	Corpus Luteum Cyst	1	CTD_human
Hgene	CDH3	C0029927	Ovarian Cysts	1	CTD_human

Fusion Gene Studies in Kim Lab

Fusion gene:CDH3-C16orf70 (FusionGDB2 ID:HG1001TG80262)

Fusion Gene Summary for CDH3-C16orf70

Fusion Gene ORF analysis for CDH3-C16orf70

Fusion Genomic Features for CDH3-C16orf70

Fusion Protein Features for CDH3-C16orf70

Fusion Gene Sequence for CDH3-C16orf70

Fusion Gene PPI Analysis for CDH3-C16orf70

Related Drugs for CDH3-C16orf70

Related Diseases for CDH3-C16orf70

Fusion Gene Studies
in Kim Lab