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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TSPAN3-ELF1 (FusionGDB2 ID:HG10099TG1997)

Fusion Gene Summary for TSPAN3-ELF1

check button Fusion gene summary
Fusion gene informationFusion gene name: TSPAN3-ELF1
Fusion gene ID: hg10099tg1997
HgeneTgene
Gene symbol

TSPAN3

ELF1

Gene ID

10099

1997

Gene nametetraspanin 3E74 like ETS transcription factor 1
SynonymsTM4-A|TM4SF8|TSPAN-3EFTUD1|RIA1
Cytomap('TSPAN3')('ELF1')

15q24.3

13q14.11

Type of geneprotein-codingprotein-coding
Descriptiontetraspanin-3tetraspan 3tetraspan TM4SFtetraspanin TM4-Atransmembrane 4 superfamily member 8ETS-related transcription factor Elf-1E74-like factor 1 (ets domain transcription factor)
Modification date2020032220200313
UniProtAcc.

P32519

Ensembl transtripts involved in fusion geneENST00000267970, ENST00000346495, 
ENST00000424443, ENST00000559494, 
ENST00000558394, ENST00000558745, 
ENST00000561277, 
Fusion gene scores* DoF score13 X 10 X 7=91013 X 11 X 5=715
# samples 1413
** MAII scorelog2(14/910*10)=-2.70043971814109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/715*10)=-2.4594316186373
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TSPAN3 [Title/Abstract] AND ELF1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTSPAN3(77363234)-ELF1(41533152), # samples:1
Anticipated loss of major functional domain due to fusion event.TSPAN3-ELF1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
TSPAN3-ELF1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneELF1

GO:0045893

positive regulation of transcription, DNA-templated

19674970

TgeneELF1

GO:0045944

positive regulation of transcription by RNA polymerase II

8756667|14970218|19674970


check buttonFusion gene breakpoints across TSPAN3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ELF1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-4371-01ATSPAN3chr15

77363234

-ELF1chr13

41533152

-


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Fusion Gene ORF analysis for TSPAN3-ELF1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000267970ENST00000239882TSPAN3chr15

77363234

-ELF1chr13

41533152

-
5CDS-5UTRENST00000267970ENST00000498824TSPAN3chr15

77363234

-ELF1chr13

41533152

-
5CDS-5UTRENST00000346495ENST00000239882TSPAN3chr15

77363234

-ELF1chr13

41533152

-
5CDS-5UTRENST00000346495ENST00000498824TSPAN3chr15

77363234

-ELF1chr13

41533152

-
5CDS-5UTRENST00000424443ENST00000239882TSPAN3chr15

77363234

-ELF1chr13

41533152

-
5CDS-5UTRENST00000424443ENST00000498824TSPAN3chr15

77363234

-ELF1chr13

41533152

-
5CDS-5UTRENST00000559494ENST00000239882TSPAN3chr15

77363234

-ELF1chr13

41533152

-
5CDS-5UTRENST00000559494ENST00000498824TSPAN3chr15

77363234

-ELF1chr13

41533152

-
5UTR-3CDSENST00000558394ENST00000442101TSPAN3chr15

77363234

-ELF1chr13

41533152

-
5UTR-5UTRENST00000558394ENST00000239882TSPAN3chr15

77363234

-ELF1chr13

41533152

-
5UTR-5UTRENST00000558394ENST00000498824TSPAN3chr15

77363234

-ELF1chr13

41533152

-
In-frameENST00000267970ENST00000442101TSPAN3chr15

77363234

-ELF1chr13

41533152

-
In-frameENST00000346495ENST00000442101TSPAN3chr15

77363234

-ELF1chr13

41533152

-
In-frameENST00000424443ENST00000442101TSPAN3chr15

77363234

-ELF1chr13

41533152

-
In-frameENST00000559494ENST00000442101TSPAN3chr15

77363234

-ELF1chr13

41533152

-
intron-3CDSENST00000558745ENST00000442101TSPAN3chr15

77363234

-ELF1chr13

41533152

-
intron-3CDSENST00000561277ENST00000442101TSPAN3chr15

77363234

-ELF1chr13

41533152

-
intron-5UTRENST00000558745ENST00000239882TSPAN3chr15

77363234

-ELF1chr13

41533152

-
intron-5UTRENST00000558745ENST00000498824TSPAN3chr15

77363234

-ELF1chr13

41533152

-
intron-5UTRENST00000561277ENST00000239882TSPAN3chr15

77363234

-ELF1chr13

41533152

-
intron-5UTRENST00000561277ENST00000498824TSPAN3chr15

77363234

-ELF1chr13

41533152

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000267970TSPAN3chr1577363234-ENST00000442101ELF1chr1341533152-3558337252052675
ENST00000346495TSPAN3chr1577363234-ENST00000442101ELF1chr1341533152-343921821933643
ENST00000424443TSPAN3chr1577363234-ENST00000442101ELF1chr1341533152-343921821933643
ENST00000559494TSPAN3chr1577363234-ENST00000442101ELF1chr1341533152-3364143801858592

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000267970ENST00000442101TSPAN3chr1577363234-ELF1chr1341533152-0.0004563380.9995436
ENST00000346495ENST00000442101TSPAN3chr1577363234-ELF1chr1341533152-0.0003906290.9996094
ENST00000424443ENST00000442101TSPAN3chr1577363234-ELF1chr1341533152-0.0003906290.9996094
ENST00000559494ENST00000442101TSPAN3chr1577363234-ELF1chr1341533152-0.0003761960.9996238

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Fusion Genomic Features for TSPAN3-ELF1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for TSPAN3-ELF1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:77363234/chr13:41533152)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ELF1

P32519

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer. {ECO:0000269|PubMed:8756667}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000267970-171_1121254.0Topological domainCytoplasmic
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000346495-161_1121229.0Topological domainCytoplasmic
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000424443-161_1121190.0Topological domainCytoplasmic
TgeneELF1chr15:77363234chr13:41533152ENST000002398821975_8024620.0Compositional biasNote=Poly-Asp
TgeneELF1chr15:77363234chr13:41533152ENST000004421010875_8024596.0Compositional biasNote=Poly-Asp
TgeneELF1chr15:77363234chr13:41533152ENST0000023988219208_29024620.0DNA bindingETS
TgeneELF1chr15:77363234chr13:41533152ENST0000044210108208_29024596.0DNA bindingETS

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000267970-17107_21221254.0Topological domainExtracellular
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000267970-17234_25321254.0Topological domainCytoplasmic
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000267970-1733_5021254.0Topological domainExtracellular
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000267970-1772_8521254.0Topological domainCytoplasmic
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000346495-16107_21221229.0Topological domainExtracellular
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000346495-16234_25321229.0Topological domainCytoplasmic
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000346495-1633_5021229.0Topological domainExtracellular
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000346495-1672_8521229.0Topological domainCytoplasmic
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000424443-16107_21221190.0Topological domainExtracellular
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000424443-16234_25321190.0Topological domainCytoplasmic
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000424443-1633_5021190.0Topological domainExtracellular
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000424443-1672_8521190.0Topological domainCytoplasmic
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000267970-1712_3221254.0TransmembraneHelical
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000267970-17213_23321254.0TransmembraneHelical
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000267970-1751_7121254.0TransmembraneHelical
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000267970-1786_10621254.0TransmembraneHelical
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000346495-1612_3221229.0TransmembraneHelical
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000346495-16213_23321229.0TransmembraneHelical
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000346495-1651_7121229.0TransmembraneHelical
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000346495-1686_10621229.0TransmembraneHelical
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000424443-1612_3221190.0TransmembraneHelical
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000424443-16213_23321190.0TransmembraneHelical
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000424443-1651_7121190.0TransmembraneHelical
HgeneTSPAN3chr15:77363234chr13:41533152ENST00000424443-1686_10621190.0TransmembraneHelical


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Fusion Gene Sequence for TSPAN3-ELF1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>94754_94754_1_TSPAN3-ELF1_TSPAN3_chr15_77363234_ENST00000267970_ELF1_chr13_41533152_ENST00000442101_length(transcript)=3558nt_BP=337nt
CTGCAGCCTCCGCAGAGGCGATTGGCTGAAGCTACCGGCCGCGTGGGGCGGGACTCGGTTGCCAGGGAGCGGCGCGGGAGCCCTGAGGGG
ACTGCGGCGGCTGCGCGGAGGAGCGAGGCACTTGCTGGGGTCGGGGCTGCGCGACGGCGCAGGGGCTGCGGGGAGCGCCGCGCAGGCCGT
GCAGTTCCTAGCGAGGAGGCGCCGCCGCCATTGCCGCTCTCTCGGTGAGCGCAGCCCCGCTCTCCGGGCCGGGCCTTCGCGGGCCACCGG
CGCCATGGGCCAGTGCGGCATCACCTCCTCCAAGACCGTGCTGGTCTTTCTCAACCTCATCTTCTGGCTTGGTGATCCAGCTATTTTTCC
TGCCGTAATTGTGGAACATGTTCCTGGTGCTGATATTCTCAATAGTTATGCCGGTCTAGCCTGTGTGGAAGAGCCCAATGACATGATTAC
TGAGAGTTCACTGGATGTTGCTGAAGAAGAAATCATAGACGATGATGATGATGACATCACCCTTACAGTTGAAGCTTCTTGTCATGACGG
GGATGAAACAATTGAAACTATTGAGGCTGCTGAGGCACTCCTCAATATGGATTCCCCTGGCCCTATGCTGGATGAAAAACGAATAAATGG
GATTCCTGAAGTGATGGAAACACAGCAGGTGCAAGAAAAATATGCAGACTCACCGGGAGCCTCATCACCAGAACAGCCTAAGAGGAAAAA
AGGAAGAAAAACTAAACCACCACGACCAGATTCCCCAGCCACTACGCCAAATATATCTGTGAAGAAGAAAAACAAAGATGGAAAGGGAAA
CACAATTTATCTTTGGGAGTTTTTACTGGCACTGCTCCAGGACAAGGCTACTTGTCCTAAATACATCAAGTGGACCCAGCGAGAGAAAGG
CATTTTTAAATTGGTGGATTCTAAAGCAGTGTCCAGGTTGTGGGGGAAGCACAAAAACAAACCTGATATGAATTATGAGACCATGGGAAG
AGCACTCAGGTACTATTACCAAAGGGGTATTCTGGCAAAAGTGGAAGGTCAGCGCTTGGTGTATCAGTTTAAAGAAATGCCAAAAGATCT
TATATATATAAATGATGAGGATCCAAGTTCCAGCATAGAGTCTTCAGATCCATCGCTATCTTCATCAGCCACTTCAAATAGGAATCAAAC
CAGCCGGTCGAGAGTATCTTCAAGTCCAGGGGTAAAAGGAGGAGCCACTACAGTTCTAAAACCAGGGAATTCTAAAGCTGCAAAACCCAA
AGATCCTGTGGAAGTTGCACAACCATCAGAAGTTTTGAGGACAGTGCAGCCCACGCAGTCTCCATATCCTACCCAGCTCTTCCGGACTGT
TCATGTAGTACAGCCAGTACAGGCTGTCCCAGAGGGAGAAGCAGCTAGAACCAGTACCATGCAGGATGAAACATTAAATTCTTCCGTTCA
GAGTATTAGGACTATACAGGCTCCAACCCAAGTTCCAGTGGTTGTGTCTCCTAGGAATCAGCAGTTGCATACAGTAACACTCCAAACAGT
GCCACTCACAACAGTTATAGCCAGCACAGATCCATCAGCAGGTACTGGATCTCAGAAGTTTATTTTACAAGCCATTCCATCATCACAGCC
CATGACAGTACTGAAAGAAAATGTCATGCTGCAGTCACAAAAGGCGGGCTCTCCTCCTTCAATTGTCTTGGGCCCTGCCCAGGTTCAGCA
GGTCCTTACTAGCAATGTTCAGACCATTTGCAATGGAACCGTCAGTGTGGCTTCCTCTCCATCCTTCAGTGCTACTGCACCTGTGGTGAC
CTTTTCTCCTCGCAGTTCACAGCTGGTTGCTCACCCACCTGGCACTGTAATCACTTCAGTTATCAAAACTCAAGAAACAAAAACTCTTAC
ACAGGAAGTAGAGAAAAAGGAATCTGAAGATCATTTGAAAGAGAACACTGAGAAAACGGAGCAGCAGCCACAGCCTTATGTGATGGTAGT
GTCCAGTTCCAATGGATTTACTTCTCAGGTAGCTATGAAACAAAACGAACTGCTGGAACCCAACTCTTTTTAGTTAATATACCAAAGCTT
ATGAATAATTGTTTGTTAATTGAACATTTTCAATTATATGCAGACTGACTGATTCTAAGATAAATTCTAAGGAGGTTTCTAATTTTGTAA
TTGTTAAAAATAGAGTTAATTTTGACTTTGTTAGATGAGGGAGGAAAACTCAACTGTTTCTCTTTGTTATCTAAATGTTTCAGAATTCAA
TCGTGAAGGAACAGGCATTTTACACTATGAAGACATTCTTTTGAGATTTTTATTTCAGTTGCTATATCATAAGCATTTTTAAAGTTTCTT
TTCTAATTTTACATTGTATTAGATTTTCTGATTCTTTTGTAAATACAGAACTTAAATAGAAGGCAACAGGAAATTTATATAGGAACTATT
TTCATTCCACTTGTGTAAGTTAAGTCTTGACTCTTTCAAATGCAAAAAACCTATTTTATGCTTTGTTAAAATTATGGTGTCACTTAGATT
GACTTTAGTTGACTGCACTATATAATATAGAACTATGAATATGTAGAATAACATGAAAAATTGGAGGTGCTGGTGGTATGGCTGACCCTG
TTTCAGAAGCAGGATAGTATAAAAGCATCAGCCTAAGAATGGCACTCCCACTAACTAGCTATGTAATCTTGACCTCTTTGGGCTTTAGTT
CCTCTCATAAAAGGAAGAGATGTATTGGATTAGACTAGATGATCACCACTTTCTCTTCTAGTTCTAATTTTTTTAATTCTAATACCTATA
TTTTCAAGTTATGTCAATTAAATCATTATCAGGTTATTTCCTAATGTAAGAATAGCTAAAATGTTGCAGAGAAATAAGTGACCCAACAAA
ATTTATTCATCTGTTATGGGTAAGATCTGCCATAAATTCTTCCTAAATAATTTGTTTACTAACTCTTTAGGCCACTGTGCTTTGCGGTCC
ATTAGTAAACTTGTGTTGCTAAGTGCTAAACAGAATACTGCTATTTTGAGAGAGTCAAGACTCTTTCTTAAGGGCCAAGAAAGCAACTTG
AGCCTTGGGCTAATCTGGCTGAGTAGTCAGTTATAAAAGCATAATTGCTTTATATTTTGGATCATTTTTTACTGGGGGCGGACTTGGGGG
GGGTTGCATACAAAGATAACATATATATCCAACTTTCTGAAATGAAATGTTTTTAGATTACTTTTTCAACTGTAAATAATGTACATTTAA
TGTCACAAGAAAAAAATGTCTTCTGCAAATTTTCTAGTATAACAGAAATTTTTGTAGATGAAAAAAATCATTATGTTTAGAGGTCTAATG
CTATGTTTTCATATTACAGAGTGAATTTGTATTTAAACAAAAATTTAAATTTTGGAATCCTCTAAACATTTTTGTATCTTTAATTGGTTT
ATTATTAAATAAATCATATAAAAATTCTCAGTGTCTGTTTTCAGGCAAAAGTTTCTTAAAGAATAAGTGTGCAGAGAATATTACTAGAAC
ATCAGCATTACTTAATGTTTATAAATAAATTTCATTAGTCAGAATTGC

>94754_94754_1_TSPAN3-ELF1_TSPAN3_chr15_77363234_ENST00000267970_ELF1_chr13_41533152_ENST00000442101_length(amino acids)=675AA_BP=104
MKLPAAWGGTRLPGSGAGALRGLRRLRGGARHLLGSGLRDGAGAAGSAAQAVQFLARRRRRHCRSLGERSPALRAGPSRATGAMGQCGIT
SSKTVLVFLNLIFWLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHDGDETIETIE
AAEALLNMDSPGPMLDEKRINGIPEVMETQQVQEKYADSPGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFL
LALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYINDEDP
SSSIESSDPSLSSSATSNRNQTSRSRVSSSPGVKGGATTVLKPGNSKAAKPKDPVEVAQPSEVLRTVQPTQSPYPTQLFRTVHVVQPVQA
VPEGEAARTSTMQDETLNSSVQSIRTIQAPTQVPVVVSPRNQQLHTVTLQTVPLTTVIASTDPSAGTGSQKFILQAIPSSQPMTVLKENV
MLQSQKAGSPPSIVLGPAQVQQVLTSNVQTICNGTVSVASSPSFSATAPVVTFSPRSSQLVAHPPGTVITSVIKTQETKTLTQEVEKKES
EDHLKENTEKTEQQPQPYVMVVSSSNGFTSQVAMKQNELLEPNSF

--------------------------------------------------------------
>94754_94754_2_TSPAN3-ELF1_TSPAN3_chr15_77363234_ENST00000346495_ELF1_chr13_41533152_ENST00000442101_length(transcript)=3439nt_BP=218nt
ACTTGCTGGGGTCGGGGCTGCGCGACGGCGCAGGGGCTGCGGGGAGCGCCGCGCAGGCCGTGCAGTTCCTAGCGAGGAGGCGCCGCCGCC
ATTGCCGCTCTCTCGGTGAGCGCAGCCCCGCTCTCCGGGCCGGGCCTTCGCGGGCCACCGGCGCCATGGGCCAGTGCGGCATCACCTCCT
CCAAGACCGTGCTGGTCTTTCTCAACCTCATCTTCTGGCTTGGTGATCCAGCTATTTTTCCTGCCGTAATTGTGGAACATGTTCCTGGTG
CTGATATTCTCAATAGTTATGCCGGTCTAGCCTGTGTGGAAGAGCCCAATGACATGATTACTGAGAGTTCACTGGATGTTGCTGAAGAAG
AAATCATAGACGATGATGATGATGACATCACCCTTACAGTTGAAGCTTCTTGTCATGACGGGGATGAAACAATTGAAACTATTGAGGCTG
CTGAGGCACTCCTCAATATGGATTCCCCTGGCCCTATGCTGGATGAAAAACGAATAAATGGGATTCCTGAAGTGATGGAAACACAGCAGG
TGCAAGAAAAATATGCAGACTCACCGGGAGCCTCATCACCAGAACAGCCTAAGAGGAAAAAAGGAAGAAAAACTAAACCACCACGACCAG
ATTCCCCAGCCACTACGCCAAATATATCTGTGAAGAAGAAAAACAAAGATGGAAAGGGAAACACAATTTATCTTTGGGAGTTTTTACTGG
CACTGCTCCAGGACAAGGCTACTTGTCCTAAATACATCAAGTGGACCCAGCGAGAGAAAGGCATTTTTAAATTGGTGGATTCTAAAGCAG
TGTCCAGGTTGTGGGGGAAGCACAAAAACAAACCTGATATGAATTATGAGACCATGGGAAGAGCACTCAGGTACTATTACCAAAGGGGTA
TTCTGGCAAAAGTGGAAGGTCAGCGCTTGGTGTATCAGTTTAAAGAAATGCCAAAAGATCTTATATATATAAATGATGAGGATCCAAGTT
CCAGCATAGAGTCTTCAGATCCATCGCTATCTTCATCAGCCACTTCAAATAGGAATCAAACCAGCCGGTCGAGAGTATCTTCAAGTCCAG
GGGTAAAAGGAGGAGCCACTACAGTTCTAAAACCAGGGAATTCTAAAGCTGCAAAACCCAAAGATCCTGTGGAAGTTGCACAACCATCAG
AAGTTTTGAGGACAGTGCAGCCCACGCAGTCTCCATATCCTACCCAGCTCTTCCGGACTGTTCATGTAGTACAGCCAGTACAGGCTGTCC
CAGAGGGAGAAGCAGCTAGAACCAGTACCATGCAGGATGAAACATTAAATTCTTCCGTTCAGAGTATTAGGACTATACAGGCTCCAACCC
AAGTTCCAGTGGTTGTGTCTCCTAGGAATCAGCAGTTGCATACAGTAACACTCCAAACAGTGCCACTCACAACAGTTATAGCCAGCACAG
ATCCATCAGCAGGTACTGGATCTCAGAAGTTTATTTTACAAGCCATTCCATCATCACAGCCCATGACAGTACTGAAAGAAAATGTCATGC
TGCAGTCACAAAAGGCGGGCTCTCCTCCTTCAATTGTCTTGGGCCCTGCCCAGGTTCAGCAGGTCCTTACTAGCAATGTTCAGACCATTT
GCAATGGAACCGTCAGTGTGGCTTCCTCTCCATCCTTCAGTGCTACTGCACCTGTGGTGACCTTTTCTCCTCGCAGTTCACAGCTGGTTG
CTCACCCACCTGGCACTGTAATCACTTCAGTTATCAAAACTCAAGAAACAAAAACTCTTACACAGGAAGTAGAGAAAAAGGAATCTGAAG
ATCATTTGAAAGAGAACACTGAGAAAACGGAGCAGCAGCCACAGCCTTATGTGATGGTAGTGTCCAGTTCCAATGGATTTACTTCTCAGG
TAGCTATGAAACAAAACGAACTGCTGGAACCCAACTCTTTTTAGTTAATATACCAAAGCTTATGAATAATTGTTTGTTAATTGAACATTT
TCAATTATATGCAGACTGACTGATTCTAAGATAAATTCTAAGGAGGTTTCTAATTTTGTAATTGTTAAAAATAGAGTTAATTTTGACTTT
GTTAGATGAGGGAGGAAAACTCAACTGTTTCTCTTTGTTATCTAAATGTTTCAGAATTCAATCGTGAAGGAACAGGCATTTTACACTATG
AAGACATTCTTTTGAGATTTTTATTTCAGTTGCTATATCATAAGCATTTTTAAAGTTTCTTTTCTAATTTTACATTGTATTAGATTTTCT
GATTCTTTTGTAAATACAGAACTTAAATAGAAGGCAACAGGAAATTTATATAGGAACTATTTTCATTCCACTTGTGTAAGTTAAGTCTTG
ACTCTTTCAAATGCAAAAAACCTATTTTATGCTTTGTTAAAATTATGGTGTCACTTAGATTGACTTTAGTTGACTGCACTATATAATATA
GAACTATGAATATGTAGAATAACATGAAAAATTGGAGGTGCTGGTGGTATGGCTGACCCTGTTTCAGAAGCAGGATAGTATAAAAGCATC
AGCCTAAGAATGGCACTCCCACTAACTAGCTATGTAATCTTGACCTCTTTGGGCTTTAGTTCCTCTCATAAAAGGAAGAGATGTATTGGA
TTAGACTAGATGATCACCACTTTCTCTTCTAGTTCTAATTTTTTTAATTCTAATACCTATATTTTCAAGTTATGTCAATTAAATCATTAT
CAGGTTATTTCCTAATGTAAGAATAGCTAAAATGTTGCAGAGAAATAAGTGACCCAACAAAATTTATTCATCTGTTATGGGTAAGATCTG
CCATAAATTCTTCCTAAATAATTTGTTTACTAACTCTTTAGGCCACTGTGCTTTGCGGTCCATTAGTAAACTTGTGTTGCTAAGTGCTAA
ACAGAATACTGCTATTTTGAGAGAGTCAAGACTCTTTCTTAAGGGCCAAGAAAGCAACTTGAGCCTTGGGCTAATCTGGCTGAGTAGTCA
GTTATAAAAGCATAATTGCTTTATATTTTGGATCATTTTTTACTGGGGGCGGACTTGGGGGGGGTTGCATACAAAGATAACATATATATC
CAACTTTCTGAAATGAAATGTTTTTAGATTACTTTTTCAACTGTAAATAATGTACATTTAATGTCACAAGAAAAAAATGTCTTCTGCAAA
TTTTCTAGTATAACAGAAATTTTTGTAGATGAAAAAAATCATTATGTTTAGAGGTCTAATGCTATGTTTTCATATTACAGAGTGAATTTG
TATTTAAACAAAAATTTAAATTTTGGAATCCTCTAAACATTTTTGTATCTTTAATTGGTTTATTATTAAATAAATCATATAAAAATTCTC
AGTGTCTGTTTTCAGGCAAAAGTTTCTTAAAGAATAAGTGTGCAGAGAATATTACTAGAACATCAGCATTACTTAATGTTTATAAATAAA
TTTCATTAGTCAGAATTGC

>94754_94754_2_TSPAN3-ELF1_TSPAN3_chr15_77363234_ENST00000346495_ELF1_chr13_41533152_ENST00000442101_length(amino acids)=643AA_BP=72
LLGSGLRDGAGAAGSAAQAVQFLARRRRRHCRSLGERSPALRAGPSRATGAMGQCGITSSKTVLVFLNLIFWLGDPAIFPAVIVEHVPGA
DILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHDGDETIETIEAAEALLNMDSPGPMLDEKRINGIPEVMETQQV
QEKYADSPGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAV
SRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYINDEDPSSSIESSDPSLSSSATSNRNQTSRSRVSSSPG
VKGGATTVLKPGNSKAAKPKDPVEVAQPSEVLRTVQPTQSPYPTQLFRTVHVVQPVQAVPEGEAARTSTMQDETLNSSVQSIRTIQAPTQ
VPVVVSPRNQQLHTVTLQTVPLTTVIASTDPSAGTGSQKFILQAIPSSQPMTVLKENVMLQSQKAGSPPSIVLGPAQVQQVLTSNVQTIC
NGTVSVASSPSFSATAPVVTFSPRSSQLVAHPPGTVITSVIKTQETKTLTQEVEKKESEDHLKENTEKTEQQPQPYVMVVSSSNGFTSQV
AMKQNELLEPNSF

--------------------------------------------------------------
>94754_94754_3_TSPAN3-ELF1_TSPAN3_chr15_77363234_ENST00000424443_ELF1_chr13_41533152_ENST00000442101_length(transcript)=3439nt_BP=218nt
ACTTGCTGGGGTCGGGGCTGCGCGACGGCGCAGGGGCTGCGGGGAGCGCCGCGCAGGCCGTGCAGTTCCTAGCGAGGAGGCGCCGCCGCC
ATTGCCGCTCTCTCGGTGAGCGCAGCCCCGCTCTCCGGGCCGGGCCTTCGCGGGCCACCGGCGCCATGGGCCAGTGCGGCATCACCTCCT
CCAAGACCGTGCTGGTCTTTCTCAACCTCATCTTCTGGCTTGGTGATCCAGCTATTTTTCCTGCCGTAATTGTGGAACATGTTCCTGGTG
CTGATATTCTCAATAGTTATGCCGGTCTAGCCTGTGTGGAAGAGCCCAATGACATGATTACTGAGAGTTCACTGGATGTTGCTGAAGAAG
AAATCATAGACGATGATGATGATGACATCACCCTTACAGTTGAAGCTTCTTGTCATGACGGGGATGAAACAATTGAAACTATTGAGGCTG
CTGAGGCACTCCTCAATATGGATTCCCCTGGCCCTATGCTGGATGAAAAACGAATAAATGGGATTCCTGAAGTGATGGAAACACAGCAGG
TGCAAGAAAAATATGCAGACTCACCGGGAGCCTCATCACCAGAACAGCCTAAGAGGAAAAAAGGAAGAAAAACTAAACCACCACGACCAG
ATTCCCCAGCCACTACGCCAAATATATCTGTGAAGAAGAAAAACAAAGATGGAAAGGGAAACACAATTTATCTTTGGGAGTTTTTACTGG
CACTGCTCCAGGACAAGGCTACTTGTCCTAAATACATCAAGTGGACCCAGCGAGAGAAAGGCATTTTTAAATTGGTGGATTCTAAAGCAG
TGTCCAGGTTGTGGGGGAAGCACAAAAACAAACCTGATATGAATTATGAGACCATGGGAAGAGCACTCAGGTACTATTACCAAAGGGGTA
TTCTGGCAAAAGTGGAAGGTCAGCGCTTGGTGTATCAGTTTAAAGAAATGCCAAAAGATCTTATATATATAAATGATGAGGATCCAAGTT
CCAGCATAGAGTCTTCAGATCCATCGCTATCTTCATCAGCCACTTCAAATAGGAATCAAACCAGCCGGTCGAGAGTATCTTCAAGTCCAG
GGGTAAAAGGAGGAGCCACTACAGTTCTAAAACCAGGGAATTCTAAAGCTGCAAAACCCAAAGATCCTGTGGAAGTTGCACAACCATCAG
AAGTTTTGAGGACAGTGCAGCCCACGCAGTCTCCATATCCTACCCAGCTCTTCCGGACTGTTCATGTAGTACAGCCAGTACAGGCTGTCC
CAGAGGGAGAAGCAGCTAGAACCAGTACCATGCAGGATGAAACATTAAATTCTTCCGTTCAGAGTATTAGGACTATACAGGCTCCAACCC
AAGTTCCAGTGGTTGTGTCTCCTAGGAATCAGCAGTTGCATACAGTAACACTCCAAACAGTGCCACTCACAACAGTTATAGCCAGCACAG
ATCCATCAGCAGGTACTGGATCTCAGAAGTTTATTTTACAAGCCATTCCATCATCACAGCCCATGACAGTACTGAAAGAAAATGTCATGC
TGCAGTCACAAAAGGCGGGCTCTCCTCCTTCAATTGTCTTGGGCCCTGCCCAGGTTCAGCAGGTCCTTACTAGCAATGTTCAGACCATTT
GCAATGGAACCGTCAGTGTGGCTTCCTCTCCATCCTTCAGTGCTACTGCACCTGTGGTGACCTTTTCTCCTCGCAGTTCACAGCTGGTTG
CTCACCCACCTGGCACTGTAATCACTTCAGTTATCAAAACTCAAGAAACAAAAACTCTTACACAGGAAGTAGAGAAAAAGGAATCTGAAG
ATCATTTGAAAGAGAACACTGAGAAAACGGAGCAGCAGCCACAGCCTTATGTGATGGTAGTGTCCAGTTCCAATGGATTTACTTCTCAGG
TAGCTATGAAACAAAACGAACTGCTGGAACCCAACTCTTTTTAGTTAATATACCAAAGCTTATGAATAATTGTTTGTTAATTGAACATTT
TCAATTATATGCAGACTGACTGATTCTAAGATAAATTCTAAGGAGGTTTCTAATTTTGTAATTGTTAAAAATAGAGTTAATTTTGACTTT
GTTAGATGAGGGAGGAAAACTCAACTGTTTCTCTTTGTTATCTAAATGTTTCAGAATTCAATCGTGAAGGAACAGGCATTTTACACTATG
AAGACATTCTTTTGAGATTTTTATTTCAGTTGCTATATCATAAGCATTTTTAAAGTTTCTTTTCTAATTTTACATTGTATTAGATTTTCT
GATTCTTTTGTAAATACAGAACTTAAATAGAAGGCAACAGGAAATTTATATAGGAACTATTTTCATTCCACTTGTGTAAGTTAAGTCTTG
ACTCTTTCAAATGCAAAAAACCTATTTTATGCTTTGTTAAAATTATGGTGTCACTTAGATTGACTTTAGTTGACTGCACTATATAATATA
GAACTATGAATATGTAGAATAACATGAAAAATTGGAGGTGCTGGTGGTATGGCTGACCCTGTTTCAGAAGCAGGATAGTATAAAAGCATC
AGCCTAAGAATGGCACTCCCACTAACTAGCTATGTAATCTTGACCTCTTTGGGCTTTAGTTCCTCTCATAAAAGGAAGAGATGTATTGGA
TTAGACTAGATGATCACCACTTTCTCTTCTAGTTCTAATTTTTTTAATTCTAATACCTATATTTTCAAGTTATGTCAATTAAATCATTAT
CAGGTTATTTCCTAATGTAAGAATAGCTAAAATGTTGCAGAGAAATAAGTGACCCAACAAAATTTATTCATCTGTTATGGGTAAGATCTG
CCATAAATTCTTCCTAAATAATTTGTTTACTAACTCTTTAGGCCACTGTGCTTTGCGGTCCATTAGTAAACTTGTGTTGCTAAGTGCTAA
ACAGAATACTGCTATTTTGAGAGAGTCAAGACTCTTTCTTAAGGGCCAAGAAAGCAACTTGAGCCTTGGGCTAATCTGGCTGAGTAGTCA
GTTATAAAAGCATAATTGCTTTATATTTTGGATCATTTTTTACTGGGGGCGGACTTGGGGGGGGTTGCATACAAAGATAACATATATATC
CAACTTTCTGAAATGAAATGTTTTTAGATTACTTTTTCAACTGTAAATAATGTACATTTAATGTCACAAGAAAAAAATGTCTTCTGCAAA
TTTTCTAGTATAACAGAAATTTTTGTAGATGAAAAAAATCATTATGTTTAGAGGTCTAATGCTATGTTTTCATATTACAGAGTGAATTTG
TATTTAAACAAAAATTTAAATTTTGGAATCCTCTAAACATTTTTGTATCTTTAATTGGTTTATTATTAAATAAATCATATAAAAATTCTC
AGTGTCTGTTTTCAGGCAAAAGTTTCTTAAAGAATAAGTGTGCAGAGAATATTACTAGAACATCAGCATTACTTAATGTTTATAAATAAA
TTTCATTAGTCAGAATTGC

>94754_94754_3_TSPAN3-ELF1_TSPAN3_chr15_77363234_ENST00000424443_ELF1_chr13_41533152_ENST00000442101_length(amino acids)=643AA_BP=72
LLGSGLRDGAGAAGSAAQAVQFLARRRRRHCRSLGERSPALRAGPSRATGAMGQCGITSSKTVLVFLNLIFWLGDPAIFPAVIVEHVPGA
DILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHDGDETIETIEAAEALLNMDSPGPMLDEKRINGIPEVMETQQV
QEKYADSPGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAV
SRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYINDEDPSSSIESSDPSLSSSATSNRNQTSRSRVSSSPG
VKGGATTVLKPGNSKAAKPKDPVEVAQPSEVLRTVQPTQSPYPTQLFRTVHVVQPVQAVPEGEAARTSTMQDETLNSSVQSIRTIQAPTQ
VPVVVSPRNQQLHTVTLQTVPLTTVIASTDPSAGTGSQKFILQAIPSSQPMTVLKENVMLQSQKAGSPPSIVLGPAQVQQVLTSNVQTIC
NGTVSVASSPSFSATAPVVTFSPRSSQLVAHPPGTVITSVIKTQETKTLTQEVEKKESEDHLKENTEKTEQQPQPYVMVVSSSNGFTSQV
AMKQNELLEPNSF

--------------------------------------------------------------
>94754_94754_4_TSPAN3-ELF1_TSPAN3_chr15_77363234_ENST00000559494_ELF1_chr13_41533152_ENST00000442101_length(transcript)=3364nt_BP=143nt
GGAGGCGCCGCCGCCATTGCCGCTCTCTCGGTGAGCGCAGCCCCGCTCTCCGGGCCGGGCCTTCGCGGGCCACCGGCGCCATGGGCCAGT
GCGGCATCACCTCCTCCAAGACCGTGCTGGTCTTTCTCAACCTCATCTTCTGGCTTGGTGATCCAGCTATTTTTCCTGCCGTAATTGTGG
AACATGTTCCTGGTGCTGATATTCTCAATAGTTATGCCGGTCTAGCCTGTGTGGAAGAGCCCAATGACATGATTACTGAGAGTTCACTGG
ATGTTGCTGAAGAAGAAATCATAGACGATGATGATGATGACATCACCCTTACAGTTGAAGCTTCTTGTCATGACGGGGATGAAACAATTG
AAACTATTGAGGCTGCTGAGGCACTCCTCAATATGGATTCCCCTGGCCCTATGCTGGATGAAAAACGAATAAATGGGATTCCTGAAGTGA
TGGAAACACAGCAGGTGCAAGAAAAATATGCAGACTCACCGGGAGCCTCATCACCAGAACAGCCTAAGAGGAAAAAAGGAAGAAAAACTA
AACCACCACGACCAGATTCCCCAGCCACTACGCCAAATATATCTGTGAAGAAGAAAAACAAAGATGGAAAGGGAAACACAATTTATCTTT
GGGAGTTTTTACTGGCACTGCTCCAGGACAAGGCTACTTGTCCTAAATACATCAAGTGGACCCAGCGAGAGAAAGGCATTTTTAAATTGG
TGGATTCTAAAGCAGTGTCCAGGTTGTGGGGGAAGCACAAAAACAAACCTGATATGAATTATGAGACCATGGGAAGAGCACTCAGGTACT
ATTACCAAAGGGGTATTCTGGCAAAAGTGGAAGGTCAGCGCTTGGTGTATCAGTTTAAAGAAATGCCAAAAGATCTTATATATATAAATG
ATGAGGATCCAAGTTCCAGCATAGAGTCTTCAGATCCATCGCTATCTTCATCAGCCACTTCAAATAGGAATCAAACCAGCCGGTCGAGAG
TATCTTCAAGTCCAGGGGTAAAAGGAGGAGCCACTACAGTTCTAAAACCAGGGAATTCTAAAGCTGCAAAACCCAAAGATCCTGTGGAAG
TTGCACAACCATCAGAAGTTTTGAGGACAGTGCAGCCCACGCAGTCTCCATATCCTACCCAGCTCTTCCGGACTGTTCATGTAGTACAGC
CAGTACAGGCTGTCCCAGAGGGAGAAGCAGCTAGAACCAGTACCATGCAGGATGAAACATTAAATTCTTCCGTTCAGAGTATTAGGACTA
TACAGGCTCCAACCCAAGTTCCAGTGGTTGTGTCTCCTAGGAATCAGCAGTTGCATACAGTAACACTCCAAACAGTGCCACTCACAACAG
TTATAGCCAGCACAGATCCATCAGCAGGTACTGGATCTCAGAAGTTTATTTTACAAGCCATTCCATCATCACAGCCCATGACAGTACTGA
AAGAAAATGTCATGCTGCAGTCACAAAAGGCGGGCTCTCCTCCTTCAATTGTCTTGGGCCCTGCCCAGGTTCAGCAGGTCCTTACTAGCA
ATGTTCAGACCATTTGCAATGGAACCGTCAGTGTGGCTTCCTCTCCATCCTTCAGTGCTACTGCACCTGTGGTGACCTTTTCTCCTCGCA
GTTCACAGCTGGTTGCTCACCCACCTGGCACTGTAATCACTTCAGTTATCAAAACTCAAGAAACAAAAACTCTTACACAGGAAGTAGAGA
AAAAGGAATCTGAAGATCATTTGAAAGAGAACACTGAGAAAACGGAGCAGCAGCCACAGCCTTATGTGATGGTAGTGTCCAGTTCCAATG
GATTTACTTCTCAGGTAGCTATGAAACAAAACGAACTGCTGGAACCCAACTCTTTTTAGTTAATATACCAAAGCTTATGAATAATTGTTT
GTTAATTGAACATTTTCAATTATATGCAGACTGACTGATTCTAAGATAAATTCTAAGGAGGTTTCTAATTTTGTAATTGTTAAAAATAGA
GTTAATTTTGACTTTGTTAGATGAGGGAGGAAAACTCAACTGTTTCTCTTTGTTATCTAAATGTTTCAGAATTCAATCGTGAAGGAACAG
GCATTTTACACTATGAAGACATTCTTTTGAGATTTTTATTTCAGTTGCTATATCATAAGCATTTTTAAAGTTTCTTTTCTAATTTTACAT
TGTATTAGATTTTCTGATTCTTTTGTAAATACAGAACTTAAATAGAAGGCAACAGGAAATTTATATAGGAACTATTTTCATTCCACTTGT
GTAAGTTAAGTCTTGACTCTTTCAAATGCAAAAAACCTATTTTATGCTTTGTTAAAATTATGGTGTCACTTAGATTGACTTTAGTTGACT
GCACTATATAATATAGAACTATGAATATGTAGAATAACATGAAAAATTGGAGGTGCTGGTGGTATGGCTGACCCTGTTTCAGAAGCAGGA
TAGTATAAAAGCATCAGCCTAAGAATGGCACTCCCACTAACTAGCTATGTAATCTTGACCTCTTTGGGCTTTAGTTCCTCTCATAAAAGG
AAGAGATGTATTGGATTAGACTAGATGATCACCACTTTCTCTTCTAGTTCTAATTTTTTTAATTCTAATACCTATATTTTCAAGTTATGT
CAATTAAATCATTATCAGGTTATTTCCTAATGTAAGAATAGCTAAAATGTTGCAGAGAAATAAGTGACCCAACAAAATTTATTCATCTGT
TATGGGTAAGATCTGCCATAAATTCTTCCTAAATAATTTGTTTACTAACTCTTTAGGCCACTGTGCTTTGCGGTCCATTAGTAAACTTGT
GTTGCTAAGTGCTAAACAGAATACTGCTATTTTGAGAGAGTCAAGACTCTTTCTTAAGGGCCAAGAAAGCAACTTGAGCCTTGGGCTAAT
CTGGCTGAGTAGTCAGTTATAAAAGCATAATTGCTTTATATTTTGGATCATTTTTTACTGGGGGCGGACTTGGGGGGGGTTGCATACAAA
GATAACATATATATCCAACTTTCTGAAATGAAATGTTTTTAGATTACTTTTTCAACTGTAAATAATGTACATTTAATGTCACAAGAAAAA
AATGTCTTCTGCAAATTTTCTAGTATAACAGAAATTTTTGTAGATGAAAAAAATCATTATGTTTAGAGGTCTAATGCTATGTTTTCATAT
TACAGAGTGAATTTGTATTTAAACAAAAATTTAAATTTTGGAATCCTCTAAACATTTTTGTATCTTTAATTGGTTTATTATTAAATAAAT
CATATAAAAATTCTCAGTGTCTGTTTTCAGGCAAAAGTTTCTTAAAGAATAAGTGTGCAGAGAATATTACTAGAACATCAGCATTACTTA
ATGTTTATAAATAAATTTCATTAGTCAGAATTGC

>94754_94754_4_TSPAN3-ELF1_TSPAN3_chr15_77363234_ENST00000559494_ELF1_chr13_41533152_ENST00000442101_length(amino acids)=592AA_BP=21
MGQCGITSSKTVLVFLNLIFWLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHDGD
ETIETIEAAEALLNMDSPGPMLDEKRINGIPEVMETQQVQEKYADSPGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNT
IYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLI
YINDEDPSSSIESSDPSLSSSATSNRNQTSRSRVSSSPGVKGGATTVLKPGNSKAAKPKDPVEVAQPSEVLRTVQPTQSPYPTQLFRTVH
VVQPVQAVPEGEAARTSTMQDETLNSSVQSIRTIQAPTQVPVVVSPRNQQLHTVTLQTVPLTTVIASTDPSAGTGSQKFILQAIPSSQPM
TVLKENVMLQSQKAGSPPSIVLGPAQVQQVLTSNVQTICNGTVSVASSPSFSATAPVVTFSPRSSQLVAHPPGTVITSVIKTQETKTLTQ
EVEKKESEDHLKENTEKTEQQPQPYVMVVSSSNGFTSQVAMKQNELLEPNSF

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TSPAN3-ELF1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TSPAN3-ELF1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TSPAN3-ELF1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource