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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DCAF7-VMP1 (FusionGDB2 ID:HG10238TG81671)

Fusion Gene Summary for DCAF7-VMP1

check button Fusion gene summary
Fusion gene informationFusion gene name: DCAF7-VMP1
Fusion gene ID: hg10238tg81671
HgeneTgene
Gene symbol

DCAF7

VMP1

Gene ID

10238

81671

Gene nameDDB1 and CUL4 associated factor 7vacuole membrane protein 1
SynonymsAN11|HAN11|SWAN-1|WDR68EPG3|TANGO5|TMEM49
Cytomap('DCAF7')('VMP1')

17q23.3

17q23.1

Type of geneprotein-codingprotein-coding
DescriptionDDB1- and CUL4-associated factor 7WD repeat-containing protein 68WD repeat-containing protein An11 homologhuman anthocyaninseven-WD-repeat protein of the AN11 family-1vacuole membrane protein 1ectopic P-granules autophagy protein 3 homologtransmembrane protein 49transport and golgi organization 5 homolog
Modification date2020031320200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000577702, ENST00000310827, 
ENST00000415273, ENST00000431926, 
Fusion gene scores* DoF score7 X 7 X 4=19642 X 34 X 19=27132
# samples 11151
** MAII scorelog2(11/196*10)=-0.833350130590549
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(151/27132*10)=-4.16737494326024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DCAF7 [Title/Abstract] AND VMP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDCAF7(61628176)-VMP1(57808782), # samples:2
Anticipated loss of major functional domain due to fusion event.DCAF7-VMP1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DCAF7-VMP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across DCAF7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across VMP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A18R-01ADCAF7chr17

61628175

+VMP1chr17

57808781

+
ChimerDB4BRCATCGA-BH-A18R-01ADCAF7chr17

61628176

-VMP1chr17

57808782

+
ChimerDB4BRCATCGA-BH-A18R-01ADCAF7chr17

61628176

+VMP1chr17

57808782

+
ChimerDB4BRCATCGA-BH-A18RDCAF7chr17

61628176

+VMP1chr17

57808781

+
ChimerDB4BRCATCGA-BH-A18RDCAF7chr17

61628176

+VMP1chr17

57842331

+


Top

Fusion Gene ORF analysis for DCAF7-VMP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000577702ENST00000262291DCAF7chr17

61628176

+VMP1chr17

57842331

+
3UTR-3CDSENST00000577702ENST00000537567DCAF7chr17

61628176

+VMP1chr17

57842331

+
3UTR-5UTRENST00000577702ENST00000262291DCAF7chr17

61628175

+VMP1chr17

57808781

+
3UTR-5UTRENST00000577702ENST00000262291DCAF7chr17

61628176

+VMP1chr17

57808782

+
3UTR-5UTRENST00000577702ENST00000262291DCAF7chr17

61628176

+VMP1chr17

57808781

+
3UTR-5UTRENST00000577702ENST00000536180DCAF7chr17

61628175

+VMP1chr17

57808781

+
3UTR-5UTRENST00000577702ENST00000536180DCAF7chr17

61628176

+VMP1chr17

57808782

+
3UTR-5UTRENST00000577702ENST00000536180DCAF7chr17

61628176

+VMP1chr17

57808781

+
3UTR-5UTRENST00000577702ENST00000536180DCAF7chr17

61628176

+VMP1chr17

57842331

+
3UTR-5UTRENST00000577702ENST00000537567DCAF7chr17

61628175

+VMP1chr17

57808781

+
3UTR-5UTRENST00000577702ENST00000537567DCAF7chr17

61628176

+VMP1chr17

57808782

+
3UTR-5UTRENST00000577702ENST00000537567DCAF7chr17

61628176

+VMP1chr17

57808781

+
3UTR-5UTRENST00000577702ENST00000539763DCAF7chr17

61628175

+VMP1chr17

57808781

+
3UTR-5UTRENST00000577702ENST00000539763DCAF7chr17

61628176

+VMP1chr17

57808782

+
3UTR-5UTRENST00000577702ENST00000539763DCAF7chr17

61628176

+VMP1chr17

57808781

+
3UTR-5UTRENST00000577702ENST00000539763DCAF7chr17

61628176

+VMP1chr17

57842331

+
3UTR-5UTRENST00000577702ENST00000545362DCAF7chr17

61628175

+VMP1chr17

57808781

+
3UTR-5UTRENST00000577702ENST00000545362DCAF7chr17

61628176

+VMP1chr17

57808782

+
3UTR-5UTRENST00000577702ENST00000545362DCAF7chr17

61628176

+VMP1chr17

57808781

+
3UTR-intronENST00000577702ENST00000545362DCAF7chr17

61628176

+VMP1chr17

57842331

+
3UTR-intronENST00000577702ENST00000588617DCAF7chr17

61628175

+VMP1chr17

57808781

+
3UTR-intronENST00000577702ENST00000588617DCAF7chr17

61628176

+VMP1chr17

57808782

+
3UTR-intronENST00000577702ENST00000588617DCAF7chr17

61628176

+VMP1chr17

57808781

+
3UTR-intronENST00000577702ENST00000588617DCAF7chr17

61628176

+VMP1chr17

57842331

+
5CDS-5UTRENST00000310827ENST00000262291DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-5UTRENST00000310827ENST00000262291DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-5UTRENST00000310827ENST00000262291DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-5UTRENST00000310827ENST00000536180DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-5UTRENST00000310827ENST00000536180DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-5UTRENST00000310827ENST00000536180DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-5UTRENST00000310827ENST00000536180DCAF7chr17

61628176

+VMP1chr17

57842331

+
5CDS-5UTRENST00000310827ENST00000537567DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-5UTRENST00000310827ENST00000537567DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-5UTRENST00000310827ENST00000537567DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-5UTRENST00000310827ENST00000539763DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-5UTRENST00000310827ENST00000539763DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-5UTRENST00000310827ENST00000539763DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-5UTRENST00000310827ENST00000539763DCAF7chr17

61628176

+VMP1chr17

57842331

+
5CDS-5UTRENST00000310827ENST00000545362DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-5UTRENST00000310827ENST00000545362DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-5UTRENST00000310827ENST00000545362DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-5UTRENST00000415273ENST00000262291DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-5UTRENST00000415273ENST00000262291DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-5UTRENST00000415273ENST00000262291DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-5UTRENST00000415273ENST00000536180DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-5UTRENST00000415273ENST00000536180DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-5UTRENST00000415273ENST00000536180DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-5UTRENST00000415273ENST00000536180DCAF7chr17

61628176

+VMP1chr17

57842331

+
5CDS-5UTRENST00000415273ENST00000537567DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-5UTRENST00000415273ENST00000537567DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-5UTRENST00000415273ENST00000537567DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-5UTRENST00000415273ENST00000539763DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-5UTRENST00000415273ENST00000539763DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-5UTRENST00000415273ENST00000539763DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-5UTRENST00000415273ENST00000539763DCAF7chr17

61628176

+VMP1chr17

57842331

+
5CDS-5UTRENST00000415273ENST00000545362DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-5UTRENST00000415273ENST00000545362DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-5UTRENST00000415273ENST00000545362DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-5UTRENST00000431926ENST00000262291DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-5UTRENST00000431926ENST00000262291DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-5UTRENST00000431926ENST00000262291DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-5UTRENST00000431926ENST00000536180DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-5UTRENST00000431926ENST00000536180DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-5UTRENST00000431926ENST00000536180DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-5UTRENST00000431926ENST00000536180DCAF7chr17

61628176

+VMP1chr17

57842331

+
5CDS-5UTRENST00000431926ENST00000537567DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-5UTRENST00000431926ENST00000537567DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-5UTRENST00000431926ENST00000537567DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-5UTRENST00000431926ENST00000539763DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-5UTRENST00000431926ENST00000539763DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-5UTRENST00000431926ENST00000539763DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-5UTRENST00000431926ENST00000539763DCAF7chr17

61628176

+VMP1chr17

57842331

+
5CDS-5UTRENST00000431926ENST00000545362DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-5UTRENST00000431926ENST00000545362DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-5UTRENST00000431926ENST00000545362DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-intronENST00000310827ENST00000545362DCAF7chr17

61628176

+VMP1chr17

57842331

+
5CDS-intronENST00000310827ENST00000588617DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-intronENST00000310827ENST00000588617DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-intronENST00000310827ENST00000588617DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-intronENST00000310827ENST00000588617DCAF7chr17

61628176

+VMP1chr17

57842331

+
5CDS-intronENST00000415273ENST00000545362DCAF7chr17

61628176

+VMP1chr17

57842331

+
5CDS-intronENST00000415273ENST00000588617DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-intronENST00000415273ENST00000588617DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-intronENST00000415273ENST00000588617DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-intronENST00000415273ENST00000588617DCAF7chr17

61628176

+VMP1chr17

57842331

+
5CDS-intronENST00000431926ENST00000545362DCAF7chr17

61628176

+VMP1chr17

57842331

+
5CDS-intronENST00000431926ENST00000588617DCAF7chr17

61628175

+VMP1chr17

57808781

+
5CDS-intronENST00000431926ENST00000588617DCAF7chr17

61628176

+VMP1chr17

57808782

+
5CDS-intronENST00000431926ENST00000588617DCAF7chr17

61628176

+VMP1chr17

57808781

+
5CDS-intronENST00000431926ENST00000588617DCAF7chr17

61628176

+VMP1chr17

57842331

+
In-frameENST00000310827ENST00000262291DCAF7chr17

61628176

+VMP1chr17

57842331

+
In-frameENST00000310827ENST00000537567DCAF7chr17

61628176

+VMP1chr17

57842331

+
In-frameENST00000415273ENST00000262291DCAF7chr17

61628176

+VMP1chr17

57842331

+
In-frameENST00000415273ENST00000537567DCAF7chr17

61628176

+VMP1chr17

57842331

+
In-frameENST00000431926ENST00000262291DCAF7chr17

61628176

+VMP1chr17

57842331

+
In-frameENST00000431926ENST00000537567DCAF7chr17

61628176

+VMP1chr17

57842331

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000310827DCAF7chr1761628176+ENST00000262291VMP1chr1757842331+23433552171161314
ENST00000310827DCAF7chr1761628176+ENST00000537567VMP1chr1757842331+14223552171161314
ENST00000431926DCAF7chr1761628176+ENST00000262291VMP1chr1757842331+23223341961140314
ENST00000431926DCAF7chr1761628176+ENST00000537567VMP1chr1757842331+14013341961140314
ENST00000415273DCAF7chr1761628176+ENST00000262291VMP1chr1757842331+23043161781122314
ENST00000415273DCAF7chr1761628176+ENST00000537567VMP1chr1757842331+13833161781122314

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000310827ENST00000262291DCAF7chr1761628176+VMP1chr1757842331+0.0003536370.9996463
ENST00000310827ENST00000537567DCAF7chr1761628176+VMP1chr1757842331+0.0010632370.9989367
ENST00000431926ENST00000262291DCAF7chr1761628176+VMP1chr1757842331+0.0003633710.99963665
ENST00000431926ENST00000537567DCAF7chr1761628176+VMP1chr1757842331+0.0011791940.99882084
ENST00000415273ENST00000262291DCAF7chr1761628176+VMP1chr1757842331+0.00035750.9996425
ENST00000415273ENST00000537567DCAF7chr1761628176+VMP1chr1757842331+0.001128310.9988716

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Fusion Genomic Features for DCAF7-VMP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DCAF7chr1761628176+VMP1chr1757808781+4.12E-060.9999958
DCAF7chr1761628176+VMP1chr1757808781+4.12E-060.9999958
DCAF7chr1761628176+VMP1chr1757842331+7.85E-070.99999917
DCAF7chr1761628176+VMP1chr1757808781+4.12E-060.9999958
DCAF7chr1761628176+VMP1chr1757808781+4.12E-060.9999958
DCAF7chr1761628176+VMP1chr1757842331+7.85E-070.99999917

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for DCAF7-VMP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:61628176/chr17:57808782)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneVMP1chr17:61628176chr17:57842331ENST00000262291412173_316138407.0RegionVTT domain
TgeneVMP1chr17:61628176chr17:57842331ENST00000262291412272_273138407.0Topological domainCytoplasmic
TgeneVMP1chr17:61628176chr17:57842331ENST00000262291412295_305138407.0Topological domainExtracellular
TgeneVMP1chr17:61628176chr17:57842331ENST00000262291412327_363138407.0Topological domainCytoplasmic
TgeneVMP1chr17:61628176chr17:57842331ENST00000262291412385_406138407.0Topological domainExtracellular
TgeneVMP1chr17:61628176chr17:57842331ENST00000262291412251_271138407.0TransmembraneHelical
TgeneVMP1chr17:61628176chr17:57842331ENST00000262291412274_294138407.0TransmembraneHelical
TgeneVMP1chr17:61628176chr17:57842331ENST00000262291412306_326138407.0TransmembraneHelical
TgeneVMP1chr17:61628176chr17:57842331ENST00000262291412364_384138407.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDCAF7chr17:61628176chr17:57842331ENST00000310827+18108_15046343.0RepeatNote=WD 3
HgeneDCAF7chr17:61628176chr17:57842331ENST00000310827+18165_20646343.0RepeatNote=WD 4
HgeneDCAF7chr17:61628176chr17:57842331ENST00000310827+18213_25246343.0RepeatNote=WD 5
HgeneDCAF7chr17:61628176chr17:57842331ENST00000310827+18257_29646343.0RepeatNote=WD 6
HgeneDCAF7chr17:61628176chr17:57842331ENST00000310827+18303_34246343.0RepeatNote=WD 7
HgeneDCAF7chr17:61628176chr17:57842331ENST00000310827+1860_10046343.0RepeatNote=WD 2
HgeneDCAF7chr17:61628176chr17:57842331ENST00000310827+186_5246343.0RepeatNote=WD 1
TgeneVMP1chr17:61628176chr17:57842331ENST00000262291412131_250138407.0Topological domainExtracellular
TgeneVMP1chr17:61628176chr17:57842331ENST000002622914122_43138407.0Topological domainCytoplasmic
TgeneVMP1chr17:61628176chr17:57842331ENST0000026229141265_77138407.0Topological domainExtracellular
TgeneVMP1chr17:61628176chr17:57842331ENST0000026229141299_109138407.0Topological domainCytoplasmic
TgeneVMP1chr17:61628176chr17:57842331ENST00000262291412110_130138407.0TransmembraneHelical
TgeneVMP1chr17:61628176chr17:57842331ENST0000026229141244_64138407.0TransmembraneHelical
TgeneVMP1chr17:61628176chr17:57842331ENST0000026229141278_98138407.0TransmembraneHelical


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Fusion Gene Sequence for DCAF7-VMP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>21539_21539_1_DCAF7-VMP1_DCAF7_chr17_61628176_ENST00000310827_VMP1_chr17_57842331_ENST00000262291_length(transcript)=2343nt_BP=355nt
AAAACGGAAGGTGGTTGTCGTCCGTTCCCAAGCTGGTTTGAAACTAGGGGTCGGGCTCGGCCGTCGTCGTTGTTTGTCGCCGCATCCCCG
CTTCCGGGTTAGGCCGTTCCTGCCCGCCCCCTCCTCTCCTCCCTTCGGACCCATAGATCTCAGGCTCGGCTCCCCGCCCGCCGCAGCCCA
CTGTTGACCCGGCCCGTACTGCGGCCCCGTGGCCACCATGTCCCTGCACGGCAAACGGAAGGAGATCTACAAGTATGAAGCGCCCTGGAC
AGTCTACGCGATGAACTGGAGTGTGCGGCCCGATAAGCGCTTTCGCTTGGCGCTGGGCAGCTTCGTGGAGGAGTACAACAACAAGGGTCC
ACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGA
TGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAAT
CGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGAT
GCTGGAACATGCAGAGTCTGCACAAGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAAT
TTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGG
TGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAAT
GGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCA
CCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCAT
CCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATAAGTAGAGAA
AGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTTTCCAACCTG
TATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGTAAGGTATCC
ACCCTCGATGCAATCCACCTTGTGTTTTCTTAGGGTGGAATGTGATGTTCAGCAGCAAACTTGCAACAGACTGGCCTTCTGTTTGTTACT
TTCAAAAGGCCCACATGATACAATTAGAGAATTCCCACCGCACAAAAAAAGTTCCTAAGTATGTTAAATATGTCAAGCTTTTTAGGCTTG
TCACAAATGATTGCTTTGTTTTCCTAAGTCATCAAAATGTATATAAATTATCTAGATTGGATAACAGTCTTGCATGTTTATCATGTTACA
ATTTAATATTCCATCCTGCCCAACCCTTCCTCTCCCATCCTCAAAAAAGGGCCATTTTATGATGCATTGCACACCCTCTGGGGAAATTGA
TCTTTAAATTTTGAGACAGTATAAGGAAAATCTGGTTGGTGTCTTACAAGTGAGCTGACACCATTTTTTATTCTGTGTATTTAGAATGAA
GTCTTGAAAAAAACTTTATAAAGACATCTTTAATCATTCCAAAATTGTGTCCGTTTTCTTGAGCGTTTTGATTTTTTACTTTTAGCTTAT
ACCAGCTGAATGGCAGCCTTGCCTAATCCACCTACAACAAGAATTTCTTAAGCTTTCTTTTATTTGCATGAGAGAGCCACTACCAAGGCA
TGTTTTGTTATGCTGAAACTGGGCTGCTGCATACTGCTAAATGGCACCTCTGGGATTGGCCTACCTGGGGATTTCTTGGTTTGTGAAAAC
AGGAGAGGAGAAATATCTCATACAAGTGAAAGGATACTGGAGAGAGAAATTACCCATTTCTAAAAAAAAACCACACTCTGTCGTATCTGT
GTTAATGTTTTCTAGCATGTACTCTGGTTTCAACAGACACAAATTTATATGTTAACCCAGTTTTCTTGCCGTTCTGTAAGTGTTTTATTC
TTAGTGTGATTTTTTTCCATTGGGATGTTTTTGATTGAACTTGTTCATTTTGTTTTGCTTGGGAGGAAAATAAACAATTTTACTTTTTTC

>21539_21539_1_DCAF7-VMP1_DCAF7_chr17_61628176_ENST00000310827_VMP1_chr17_57842331_ENST00000262291_length(amino acids)=314AA_BP=46
MSLHGKRKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWS
IISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFD
LAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGEN

--------------------------------------------------------------
>21539_21539_2_DCAF7-VMP1_DCAF7_chr17_61628176_ENST00000310827_VMP1_chr17_57842331_ENST00000537567_length(transcript)=1422nt_BP=355nt
AAAACGGAAGGTGGTTGTCGTCCGTTCCCAAGCTGGTTTGAAACTAGGGGTCGGGCTCGGCCGTCGTCGTTGTTTGTCGCCGCATCCCCG
CTTCCGGGTTAGGCCGTTCCTGCCCGCCCCCTCCTCTCCTCCCTTCGGACCCATAGATCTCAGGCTCGGCTCCCCGCCCGCCGCAGCCCA
CTGTTGACCCGGCCCGTACTGCGGCCCCGTGGCCACCATGTCCCTGCACGGCAAACGGAAGGAGATCTACAAGTATGAAGCGCCCTGGAC
AGTCTACGCGATGAACTGGAGTGTGCGGCCCGATAAGCGCTTTCGCTTGGCGCTGGGCAGCTTCGTGGAGGAGTACAACAACAAGGGTCC
ACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGA
TGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAAT
CGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGAT
GCTGGAACATGCAGAGTCTGCACAAGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAAT
TTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGG
TGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAAT
GGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCA
CCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCAT
CCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATAAGTAGAGAA
AGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTTTCCAACCTG
TATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGTAAGGTATCC

>21539_21539_2_DCAF7-VMP1_DCAF7_chr17_61628176_ENST00000310827_VMP1_chr17_57842331_ENST00000537567_length(amino acids)=314AA_BP=46
MSLHGKRKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWS
IISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFD
LAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGEN

--------------------------------------------------------------
>21539_21539_3_DCAF7-VMP1_DCAF7_chr17_61628176_ENST00000415273_VMP1_chr17_57842331_ENST00000262291_length(transcript)=2304nt_BP=316nt
GAAACTAGGGGTCGGGCTCGGCCGTCGTCGTTGTTTGTCGCCGCATCCCCGCTTCCGGGTTAGGCCGTTCCTGCCCGCCCCCTCCTCTCC
TCCCTTCGGACCCATAGATCTCAGGCTCGGCTCCCCGCCCGCCGCAGCCCACTGTTGACCCGGCCCGTACTGCGGCCCCGTGGCCACCAT
GTCCCTGCACGGCAAACGGAAGGAGATCTACAAGTATGAAGCGCCCTGGACAGTCTACGCGATGAACTGGAGTGTGCGGCCCGATAAGCG
CTTTCGCTTGGCGCTGGGCAGCTTCGTGGAGGAGTACAACAACAAGGGTCCACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAA
TTCAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTAT
CATCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCG
CCTCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGACTTTGCCTCCCG
GGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCT
GGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATAT
CCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATC
TCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTG
GTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAA
ACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATAAGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCC
TTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTTTCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGT
CCATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGTAAGGTATCCACCCTCGATGCAATCCACCTTGTGTTTTCTTAGGGTGGA
ATGTGATGTTCAGCAGCAAACTTGCAACAGACTGGCCTTCTGTTTGTTACTTTCAAAAGGCCCACATGATACAATTAGAGAATTCCCACC
GCACAAAAAAAGTTCCTAAGTATGTTAAATATGTCAAGCTTTTTAGGCTTGTCACAAATGATTGCTTTGTTTTCCTAAGTCATCAAAATG
TATATAAATTATCTAGATTGGATAACAGTCTTGCATGTTTATCATGTTACAATTTAATATTCCATCCTGCCCAACCCTTCCTCTCCCATC
CTCAAAAAAGGGCCATTTTATGATGCATTGCACACCCTCTGGGGAAATTGATCTTTAAATTTTGAGACAGTATAAGGAAAATCTGGTTGG
TGTCTTACAAGTGAGCTGACACCATTTTTTATTCTGTGTATTTAGAATGAAGTCTTGAAAAAAACTTTATAAAGACATCTTTAATCATTC
CAAAATTGTGTCCGTTTTCTTGAGCGTTTTGATTTTTTACTTTTAGCTTATACCAGCTGAATGGCAGCCTTGCCTAATCCACCTACAACA
AGAATTTCTTAAGCTTTCTTTTATTTGCATGAGAGAGCCACTACCAAGGCATGTTTTGTTATGCTGAAACTGGGCTGCTGCATACTGCTA
AATGGCACCTCTGGGATTGGCCTACCTGGGGATTTCTTGGTTTGTGAAAACAGGAGAGGAGAAATATCTCATACAAGTGAAAGGATACTG
GAGAGAGAAATTACCCATTTCTAAAAAAAAACCACACTCTGTCGTATCTGTGTTAATGTTTTCTAGCATGTACTCTGGTTTCAACAGACA
CAAATTTATATGTTAACCCAGTTTTCTTGCCGTTCTGTAAGTGTTTTATTCTTAGTGTGATTTTTTTCCATTGGGATGTTTTTGATTGAA

>21539_21539_3_DCAF7-VMP1_DCAF7_chr17_61628176_ENST00000415273_VMP1_chr17_57842331_ENST00000262291_length(amino acids)=314AA_BP=46
MSLHGKRKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWS
IISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFD
LAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGEN

--------------------------------------------------------------
>21539_21539_4_DCAF7-VMP1_DCAF7_chr17_61628176_ENST00000415273_VMP1_chr17_57842331_ENST00000537567_length(transcript)=1383nt_BP=316nt
GAAACTAGGGGTCGGGCTCGGCCGTCGTCGTTGTTTGTCGCCGCATCCCCGCTTCCGGGTTAGGCCGTTCCTGCCCGCCCCCTCCTCTCC
TCCCTTCGGACCCATAGATCTCAGGCTCGGCTCCCCGCCCGCCGCAGCCCACTGTTGACCCGGCCCGTACTGCGGCCCCGTGGCCACCAT
GTCCCTGCACGGCAAACGGAAGGAGATCTACAAGTATGAAGCGCCCTGGACAGTCTACGCGATGAACTGGAGTGTGCGGCCCGATAAGCG
CTTTCGCTTGGCGCTGGGCAGCTTCGTGGAGGAGTACAACAACAAGGGTCCACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAA
TTCAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTAT
CATCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCG
CCTCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGACTTTGCCTCCCG
GGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCT
GGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATAT
CCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATC
TCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTG
GTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAA
ACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATAAGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCC
TTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTTTCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGT
CCATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGTAAGGTATCCACCCTCGATGCAATCCACCTTGTGTTTTCTTAGGGTGGA

>21539_21539_4_DCAF7-VMP1_DCAF7_chr17_61628176_ENST00000415273_VMP1_chr17_57842331_ENST00000537567_length(amino acids)=314AA_BP=46
MSLHGKRKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWS
IISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFD
LAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGEN

--------------------------------------------------------------
>21539_21539_5_DCAF7-VMP1_DCAF7_chr17_61628176_ENST00000431926_VMP1_chr17_57842331_ENST00000262291_length(transcript)=2322nt_BP=334nt
CCGTTCCCAAGCTGGTTTGAAACTAGGGGTCGGGCTCGGCCGTCGTCGTTGTTTGTCGCCGCATCCCCGCTTCCGGGTTAGGCCGTTCCT
GCCCGCCCCCTCCTCTCCTCCCTTCGGACCCATAGATCTCAGGCTCGGCTCCCCGCCCGCCGCAGCCCACTGTTGACCCGGCCCGTACTG
CGGCCCCGTGGCCACCATGTCCCTGCACGGCAAACGGAAGGAGATCTACAAGTATGAAGCGCCCTGGACAGTCTACGCGATGAACTGGAG
TGTGCGGCCCGATAAGCGCTTTCGCTTGGCGCTGGGCAGCTTCGTGGAGGAGTACAACAACAAGGGTCCACATATAGCCTCAGTTACATT
AGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAAC
CATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTT
CATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGC
ACAAGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCC
AAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGC
AATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGT
CCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCAC
ACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCAT
GGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATAAGTAGAGAAAGTTTTAAACTGCAGAAATTG
GAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTTTCCAACCTGTATCAATTTTTACAACTTTTT
TCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGTAAGGTATCCACCCTCGATGCAATCCACCTT
GTGTTTTCTTAGGGTGGAATGTGATGTTCAGCAGCAAACTTGCAACAGACTGGCCTTCTGTTTGTTACTTTCAAAAGGCCCACATGATAC
AATTAGAGAATTCCCACCGCACAAAAAAAGTTCCTAAGTATGTTAAATATGTCAAGCTTTTTAGGCTTGTCACAAATGATTGCTTTGTTT
TCCTAAGTCATCAAAATGTATATAAATTATCTAGATTGGATAACAGTCTTGCATGTTTATCATGTTACAATTTAATATTCCATCCTGCCC
AACCCTTCCTCTCCCATCCTCAAAAAAGGGCCATTTTATGATGCATTGCACACCCTCTGGGGAAATTGATCTTTAAATTTTGAGACAGTA
TAAGGAAAATCTGGTTGGTGTCTTACAAGTGAGCTGACACCATTTTTTATTCTGTGTATTTAGAATGAAGTCTTGAAAAAAACTTTATAA
AGACATCTTTAATCATTCCAAAATTGTGTCCGTTTTCTTGAGCGTTTTGATTTTTTACTTTTAGCTTATACCAGCTGAATGGCAGCCTTG
CCTAATCCACCTACAACAAGAATTTCTTAAGCTTTCTTTTATTTGCATGAGAGAGCCACTACCAAGGCATGTTTTGTTATGCTGAAACTG
GGCTGCTGCATACTGCTAAATGGCACCTCTGGGATTGGCCTACCTGGGGATTTCTTGGTTTGTGAAAACAGGAGAGGAGAAATATCTCAT
ACAAGTGAAAGGATACTGGAGAGAGAAATTACCCATTTCTAAAAAAAAACCACACTCTGTCGTATCTGTGTTAATGTTTTCTAGCATGTA
CTCTGGTTTCAACAGACACAAATTTATATGTTAACCCAGTTTTCTTGCCGTTCTGTAAGTGTTTTATTCTTAGTGTGATTTTTTTCCATT

>21539_21539_5_DCAF7-VMP1_DCAF7_chr17_61628176_ENST00000431926_VMP1_chr17_57842331_ENST00000262291_length(amino acids)=314AA_BP=46
MSLHGKRKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWS
IISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFD
LAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGEN

--------------------------------------------------------------
>21539_21539_6_DCAF7-VMP1_DCAF7_chr17_61628176_ENST00000431926_VMP1_chr17_57842331_ENST00000537567_length(transcript)=1401nt_BP=334nt
CCGTTCCCAAGCTGGTTTGAAACTAGGGGTCGGGCTCGGCCGTCGTCGTTGTTTGTCGCCGCATCCCCGCTTCCGGGTTAGGCCGTTCCT
GCCCGCCCCCTCCTCTCCTCCCTTCGGACCCATAGATCTCAGGCTCGGCTCCCCGCCCGCCGCAGCCCACTGTTGACCCGGCCCGTACTG
CGGCCCCGTGGCCACCATGTCCCTGCACGGCAAACGGAAGGAGATCTACAAGTATGAAGCGCCCTGGACAGTCTACGCGATGAACTGGAG
TGTGCGGCCCGATAAGCGCTTTCGCTTGGCGCTGGGCAGCTTCGTGGAGGAGTACAACAACAAGGGTCCACATATAGCCTCAGTTACATT
AGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAAC
CATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTT
CATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGC
ACAAGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCC
AAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGC
AATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGT
CCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCAC
ACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCAT
GGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATAAGTAGAGAAAGTTTTAAACTGCAGAAATTG
GAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTTTCCAACCTGTATCAATTTTTACAACTTTTT
TCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGTAAGGTATCCACCCTCGATGCAATCCACCTT

>21539_21539_6_DCAF7-VMP1_DCAF7_chr17_61628176_ENST00000431926_VMP1_chr17_57842331_ENST00000537567_length(amino acids)=314AA_BP=46
MSLHGKRKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWS
IISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFD
LAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGEN

--------------------------------------------------------------

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Fusion Gene PPI Analysis for DCAF7-VMP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DCAF7-VMP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DCAF7-VMP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneDCAF7C0376634Craniofacial Abnormalities1CTD_human
HgeneDCAF7C1860789Leukemia, Megakaryoblastic, of Down Syndrome1CTD_human