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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:AGPAT2-CDC42SE1 (FusionGDB2 ID:HG10555TG56882)

Fusion Gene Summary for AGPAT2-CDC42SE1

check button Fusion gene summary
Fusion gene informationFusion gene name: AGPAT2-CDC42SE1
Fusion gene ID: hg10555tg56882
HgeneTgene
Gene symbol

AGPAT2

CDC42SE1

Gene ID

10555

56882

Gene name1-acylglycerol-3-phosphate O-acyltransferase 2CDC42 small effector 1
Synonyms1-AGPAT2|BSCL|BSCL1|LPAAB|LPAAT-betaSCIP1|SPEC1
Cytomap('AGPAT2')('CDC42SE1')

9q34.3

1q21.3

Type of geneprotein-codingprotein-coding
Description1-acyl-sn-glycerol-3-phosphate acyltransferase beta1-AGP acyltransferase 21-AGPAT 21-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)lysophosphatidic acid acyltransferase-betatesticular tissue protein Li 143CDC42 small effector protein 11300002M12RikCDC42-binding protein SCIP1signaling molecule SPEC1 betasmall effector of CDC42 protein 1small protein effector 1 of Cdc42
Modification date2020031320200313
UniProtAcc

O15120

.
Ensembl transtripts involved in fusion geneENST00000371694, ENST00000371696, 
ENST00000538402, 
Fusion gene scores* DoF score1 X 1 X 1=17 X 8 X 5=280
# samples 19
** MAII scorelog2(1/1*10)=3.32192809488736log2(9/280*10)=-1.63742992061529
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AGPAT2 [Title/Abstract] AND CDC42SE1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAGPAT2(139571413)-CDC42SE1(151027602), # samples:3
Anticipated loss of major functional domain due to fusion event.AGPAT2-CDC42SE1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
AGPAT2-CDC42SE1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
AGPAT2-CDC42SE1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
AGPAT2-CDC42SE1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
AGPAT2-CDC42SE1 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
AGPAT2-CDC42SE1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across AGPAT2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CDC42SE1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A0C0-01AAGPAT2chr9

139571413

-CDC42SE1chr1

151027602

-


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Fusion Gene ORF analysis for AGPAT2-CDC42SE1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000371694ENST00000492796AGPAT2chr9

139571413

-CDC42SE1chr1

151027602

-
5CDS-5UTRENST00000371696ENST00000492796AGPAT2chr9

139571413

-CDC42SE1chr1

151027602

-
5CDS-5UTRENST00000538402ENST00000492796AGPAT2chr9

139571413

-CDC42SE1chr1

151027602

-
Frame-shiftENST00000538402ENST00000357235AGPAT2chr9

139571413

-CDC42SE1chr1

151027602

-
Frame-shiftENST00000538402ENST00000439374AGPAT2chr9

139571413

-CDC42SE1chr1

151027602

-
Frame-shiftENST00000538402ENST00000540998AGPAT2chr9

139571413

-CDC42SE1chr1

151027602

-
In-frameENST00000371694ENST00000357235AGPAT2chr9

139571413

-CDC42SE1chr1

151027602

-
In-frameENST00000371694ENST00000439374AGPAT2chr9

139571413

-CDC42SE1chr1

151027602

-
In-frameENST00000371694ENST00000540998AGPAT2chr9

139571413

-CDC42SE1chr1

151027602

-
In-frameENST00000371696ENST00000357235AGPAT2chr9

139571413

-CDC42SE1chr1

151027602

-
In-frameENST00000371696ENST00000439374AGPAT2chr9

139571413

-CDC42SE1chr1

151027602

-
In-frameENST00000371696ENST00000540998AGPAT2chr9

139571413

-CDC42SE1chr1

151027602

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000371694AGPAT2chr9139571413-ENST00000439374CDC42SE1chr1151027602-309253341718225
ENST00000371694AGPAT2chr9139571413-ENST00000540998CDC42SE1chr1151027602-309053341718225
ENST00000371694AGPAT2chr9139571413-ENST00000357235CDC42SE1chr1151027602-309053341718225
ENST00000371696AGPAT2chr9139571413-ENST00000439374CDC42SE1chr1151027602-311755866743225
ENST00000371696AGPAT2chr9139571413-ENST00000540998CDC42SE1chr1151027602-311555866743225
ENST00000371696AGPAT2chr9139571413-ENST00000357235CDC42SE1chr1151027602-311555866743225

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000371694ENST00000439374AGPAT2chr9139571413-CDC42SE1chr1151027602-0.0024861960.9975138
ENST00000371694ENST00000540998AGPAT2chr9139571413-CDC42SE1chr1151027602-0.0026002750.9973997
ENST00000371694ENST00000357235AGPAT2chr9139571413-CDC42SE1chr1151027602-0.0026002750.9973997
ENST00000371696ENST00000439374AGPAT2chr9139571413-CDC42SE1chr1151027602-0.0026020690.9973979
ENST00000371696ENST00000540998AGPAT2chr9139571413-CDC42SE1chr1151027602-0.0027147460.99728525
ENST00000371696ENST00000357235AGPAT2chr9139571413-CDC42SE1chr1151027602-0.0027147460.99728525

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Fusion Genomic Features for AGPAT2-CDC42SE1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for AGPAT2-CDC42SE1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:139571413/chr1:151027602)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
AGPAT2

O15120

.
FUNCTION: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. {ECO:0000269|PubMed:15629135, ECO:0000269|PubMed:19075029, ECO:0000269|PubMed:21873652, ECO:0000269|PubMed:9242711}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000371694-3598_103164247.0MotifHXXXXD motif
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000371696-3698_103164279.0MotifHXXXXD motif
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000538402-3798_103164379.6666666666667MotifHXXXXD motif
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000371694-3524_29164247.0Topological domainLumenal
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000371694-3551_121164247.0Topological domainCytoplasmic
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000371696-3624_29164279.0Topological domainLumenal
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000371696-3651_121164279.0Topological domainCytoplasmic
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000538402-3724_29164379.6666666666667Topological domainLumenal
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000538402-3751_121164379.6666666666667Topological domainCytoplasmic
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000371694-35122_142164247.0TransmembraneHelical
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000371694-3530_50164247.0TransmembraneHelical
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000371696-36122_142164279.0TransmembraneHelical
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000371696-3630_50164279.0TransmembraneHelical
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000538402-37122_142164379.6666666666667TransmembraneHelical
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000538402-3730_50164379.6666666666667TransmembraneHelical
TgeneCDC42SE1chr9:139571413chr1:151027602ENST000003572351530_4318732.6666666666666DomainCRIB
TgeneCDC42SE1chr9:139571413chr1:151027602ENST000004393744830_4318854.6666666666666DomainCRIB
TgeneCDC42SE1chr9:139571413chr1:151027602ENST000005409982630_4318793.0DomainCRIB
TgeneCDC42SE1chr9:139571413chr1:151027602ENST000003572351519_2418732.6666666666666RegionNote=Mediates phosphoinositide-binding
TgeneCDC42SE1chr9:139571413chr1:151027602ENST000004393744819_2418854.6666666666666RegionNote=Mediates phosphoinositide-binding
TgeneCDC42SE1chr9:139571413chr1:151027602ENST000005409982619_2418793.0RegionNote=Mediates phosphoinositide-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000371694-35172_175164247.0MotifEGTR motif
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000371696-36172_175164279.0MotifEGTR motif
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000538402-37172_175164379.6666666666667MotifEGTR motif
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000371694-35143_278164247.0Topological domainLumenal
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000371696-36143_278164279.0Topological domainLumenal
HgeneAGPAT2chr9:139571413chr1:151027602ENST00000538402-37143_278164379.6666666666667Topological domainLumenal


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Fusion Gene Sequence for AGPAT2-CDC42SE1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>2927_2927_1_AGPAT2-CDC42SE1_AGPAT2_chr9_139571413_ENST00000371694_CDC42SE1_chr1_151027602_ENST00000357235_length(transcript)=3090nt_BP=533nt
CGGGAGCGAGCTGGCGGCGCCGTCGGGCGCCGGGCCGGGCCATGGAGCTGTGGCCGTGTCTGGCCGCGGCGCTGCTGTTGCTGCTGCTGC
TGGTGCAGCTGAGCCGCGCGGCCGAGTTCTACGCCAAGGTCGCCCTGTACTGCGCGCTGTGCTTCACGGTGTCCGCCGTGGCCTCGCTCG
TCTGCCTGCTGCGCCACGGCGGCCGGACGGTGGAGAACATGAGCATCATCGGCTGGTTCGTGCGAAGCTTCAAGTACTTTTACGGGCTCC
GCTTCGAGGTGCGGGACCCGCGCAGGCTGCAGGAGGCCCGTCCCTGTGTCATCGTCTCCAACCACCAGAGCATCCTGGACATGATGGGCC
TCATGGAGGTCCTTCCGGAGCGCTGCGTGCAGATCGCCAAGCGGGAGCTGCTCTTCCTGGGGCCCGTGGGCCTCATCATGTACCTCGGGG
GCGTCTTCTTCATCAACCGGCAGCGCTCTAGCACTGCCATGACAGTGATGGCCGACCTGGGCGAGCGCATGGTCAGGGAGAACAAGAAGA
AGAGAAGACGGATTGACCGGACCATGATTGGGGAACCAATGAATTTTGTTCACCTGACTCACATTGGCTCAGGGGAGATGGGGGCCGGAG
ATGGACTTGCCATGACAGGTGCAGTTCAGGAGCAGATGAGATCCAAGGGAAACCGAGATAGGCCATGGAGCAATTCTAGGGGCTTATAGC
TCCAATAATGGAATGGTTCTGCCATCTTGAAACCCCCATTCTGTTTCCAGCCCAGAAGAAATGCTGCCCCTACCAGATCCCTCCTTGAAC
CAGTGATCTAAGGACCCCTCTTTTCCCTATCTGCCTAACAGTGCCTCACAAGGCTTGGGGGCTGGACTCCCTCTACTCCCTCTGGCCATA
GCCCCTCCTGGAGATGGGGTCAAGGCAGCAGGACTGATCAAGTGACTACTGGTTAGCCAGAGGAGCTCAGCTGAAGCCCTGGAAACCCTC
AGGTCTGAGATAGGAGTTCTCTAGGAACCTGGAATGAGTTCCTGTCTCCTGAATGATGGTCTGGGTGCCACCTGTTTTTAAACTCTTAAA
CCTGGAACTCCTTAAATGGGGTAGGTGGGTGAGATTATCAAAGCTGAAGCTGGCTTTGCTGAGAAGCTCCCTACCTCCCTGCCCTTCTCC
TCCTTCCTGCTGGAATGAACTAAAGCAGATGTCAAGCAGGGGCTGGTGGGGGTGCCTACTCCCTTTTCCACTCTATCTTTAGATTTCAAA
CCTTAGGCTTACAGCCCCTCAATATCTCTCTGCTAACACCAGTGTCTCTTTCTAGTTAGGCCTCTAATCTTCTGTTTCTGTTTACCAGCT
TCCCAGCAACTTTCCTTTTTTAAAATATTAAAAATTTAATTCAGGTTCTCTTAATTATCCTCATCCTGCTGTTGCCTCCGCCCTTAACTC
TATCCCTATTAGGAACCTTGTTTCCCACCGAATAAGAGTTAAGGTAAGAGGTAGCTCTTCACCTGATGACATTCCATTTAAGTTTTGGGG
CATCTTTCCTGCCCTCTGCCAACCTCCCTGCTGGCCCAGGTGAGAGGAGGAAGAGGGGTCTGGAAAGAAACCCAGAATGCGGCAGAACTA
GGAGTAAGTCCATCTCAAGGTGGACTTCTGATCATTGAGGATGGTGAGATAAATAGGTTGAAAACAATCATCTGTGAGTTTAGGAGTCTT
AAGATCCTCACAGCACGGGAGCAGGGAGAGGCTCTAGAACAAGGTTTCACAACCGAGATGCCTTTGACATTTTGGGCTGAAGTGTTCTTT
GTAAGGAAAACCTGTTTCCTATTTTGTGCATTACAGGATATTTAGCAGCAACCCTGGCCCACTCTAGTTATGACAACCAAAAATGTCTCT
ATACATTGCCAGATTTCTCCTAGGGGGCAAAATCGCCTCCATTTGAGAACCACAACTCTAAAGTCAAGATATTTTTCTCTGAAGTGATTT
CTGCTTGGCACGCTACCCTCATCATCTTACTCATCTTAAGCCCGAGCCATGGATCAACTAGGAGCCCATATAAATGAGGCTCAGTAGGGC
TGCACATAATCTCCAAACAATTCTTTATTCAGTGTTTTGCTTGTGTTTGCATGTTGCTATGATGGACAGGTCCCCCTCCTCCATTCTTGC
CCTCTGGAGAAGTGGTTCCTGCAGTGTAGAGATATGAACAGGGTATGGTAGGATTGGGGAAAGGGGAGAGAGAAGCAGTAGATACACTCC
TTATCCTCCCCAAATTTTAAGCTCTATTTCTGTGCCCTAGTCCTAGACACACATTAGACTCAGGGAGTTTTGTCTGAAGACCAGGTCCCA
CTGCCCCCTGGCTGAAGAGTCTGCTTTAAATGGGAAAACAACGTAGGAGCAGGGGTTTTTAGGCACTTTCAGTATTCTCAGGTGTTCTTC
GTTCTGGCCCTTCCAGGGTAATTAGGAAGGCAGAACAAGACAGATGAGCTCCTGCCTGCTCTGAGACAAGAAGGGTGGGGTCTCATTAGC
TTTGCAACAGGAAACATCCTGTTTTATGGTAGTGGGGTCAGGAATGTAGGAACTGGTATCCATTCTGCCAATTCCACCACCCATTCAGTT
TGCTTATCCCTACAGAACAGTGACTGAGGTTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCAAATTTCCATGTATTTTCTGCCATTTTTCA
GGGTCTAAGATTGGTCATACATTCCCAATTTACTCTCAGTTCCAGTCAAGCTGGTTGCTCTGAAAGTAACCCAGCTTGTTGCTCTAAAAT
ACCTCAGTAGCCTGAGTGTTATACTAGAGATCTAAAGGGTTAACAGGATAGGGTGGAAAGGTTAGAGACTCCTAGAAATCTCTGGTCACC
GTGATCTTCGGCCTCATTCTAATACCTGTTCTTTGGACAGTCTTTTTCCTTTGGTGCTCTCTTGCCTTTAGCTACCTTCTCTAATATGTA
TGCTACCATCACTAATAAAGTGATGGGAATGGGTTTGAGAGTCGTAATTTATATTAAAAAGTTGTTGGACTTTTAAATACATTTTTTCAA

>2927_2927_1_AGPAT2-CDC42SE1_AGPAT2_chr9_139571413_ENST00000371694_CDC42SE1_chr1_151027602_ENST00000357235_length(amino acids)=225AA_BP=164
MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEAR
PCVIVSNHQSILDMMGLMEVLPERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENKKKRRRIDRTMIGEPM

--------------------------------------------------------------
>2927_2927_2_AGPAT2-CDC42SE1_AGPAT2_chr9_139571413_ENST00000371694_CDC42SE1_chr1_151027602_ENST00000439374_length(transcript)=3092nt_BP=533nt
CGGGAGCGAGCTGGCGGCGCCGTCGGGCGCCGGGCCGGGCCATGGAGCTGTGGCCGTGTCTGGCCGCGGCGCTGCTGTTGCTGCTGCTGC
TGGTGCAGCTGAGCCGCGCGGCCGAGTTCTACGCCAAGGTCGCCCTGTACTGCGCGCTGTGCTTCACGGTGTCCGCCGTGGCCTCGCTCG
TCTGCCTGCTGCGCCACGGCGGCCGGACGGTGGAGAACATGAGCATCATCGGCTGGTTCGTGCGAAGCTTCAAGTACTTTTACGGGCTCC
GCTTCGAGGTGCGGGACCCGCGCAGGCTGCAGGAGGCCCGTCCCTGTGTCATCGTCTCCAACCACCAGAGCATCCTGGACATGATGGGCC
TCATGGAGGTCCTTCCGGAGCGCTGCGTGCAGATCGCCAAGCGGGAGCTGCTCTTCCTGGGGCCCGTGGGCCTCATCATGTACCTCGGGG
GCGTCTTCTTCATCAACCGGCAGCGCTCTAGCACTGCCATGACAGTGATGGCCGACCTGGGCGAGCGCATGGTCAGGGAGAACAAGAAGA
AGAGAAGACGGATTGACCGGACCATGATTGGGGAACCAATGAATTTTGTTCACCTGACTCACATTGGCTCAGGGGAGATGGGGGCCGGAG
ATGGACTTGCCATGACAGGTGCAGTTCAGGAGCAGATGAGATCCAAGGGAAACCGAGATAGGCCATGGAGCAATTCTAGGGGCTTATAGC
TCCAATAATGGAATGGTTCTGCCATCTTGAAACCCCCATTCTGTTTCCAGCCCAGAAGAAATGCTGCCCCTACCAGATCCCTCCTTGAAC
CAGTGATCTAAGGACCCCTCTTTTCCCTATCTGCCTAACAGTGCCTCACAAGGCTTGGGGGCTGGACTCCCTCTACTCCCTCTGGCCATA
GCCCCTCCTGGAGATGGGGTCAAGGCAGCAGGACTGATCAAGTGACTACTGGTTAGCCAGAGGAGCTCAGCTGAAGCCCTGGAAACCCTC
AGGTCTGAGATAGGAGTTCTCTAGGAACCTGGAATGAGTTCCTGTCTCCTGAATGATGGTCTGGGTGCCACCTGTTTTTAAACTCTTAAA
CCTGGAACTCCTTAAATGGGGTAGGTGGGTGAGATTATCAAAGCTGAAGCTGGCTTTGCTGAGAAGCTCCCTACCTCCCTGCCCTTCTCC
TCCTTCCTGCTGGAATGAACTAAAGCAGATGTCAAGCAGGGGCTGGTGGGGGTGCCTACTCCCTTTTCCACTCTATCTTTAGATTTCAAA
CCTTAGGCTTACAGCCCCTCAATATCTCTCTGCTAACACCAGTGTCTCTTTCTAGTTAGGCCTCTAATCTTCTGTTTCTGTTTACCAGCT
TCCCAGCAACTTTCCTTTTTTAAAATATTAAAAATTTAATTCAGGTTCTCTTAATTATCCTCATCCTGCTGTTGCCTCCGCCCTTAACTC
TATCCCTATTAGGAACCTTGTTTCCCACCGAATAAGAGTTAAGGTAAGAGGTAGCTCTTCACCTGATGACATTCCATTTAAGTTTTGGGG
CATCTTTCCTGCCCTCTGCCAACCTCCCTGCTGGCCCAGGTGAGAGGAGGAAGAGGGGTCTGGAAAGAAACCCAGAATGCGGCAGAACTA
GGAGTAAGTCCATCTCAAGGTGGACTTCTGATCATTGAGGATGGTGAGATAAATAGGTTGAAAACAATCATCTGTGAGTTTAGGAGTCTT
AAGATCCTCACAGCACGGGAGCAGGGAGAGGCTCTAGAACAAGGTTTCACAACCGAGATGCCTTTGACATTTTGGGCTGAAGTGTTCTTT
GTAAGGAAAACCTGTTTCCTATTTTGTGCATTACAGGATATTTAGCAGCAACCCTGGCCCACTCTAGTTATGACAACCAAAAATGTCTCT
ATACATTGCCAGATTTCTCCTAGGGGGCAAAATCGCCTCCATTTGAGAACCACAACTCTAAAGTCAAGATATTTTTCTCTGAAGTGATTT
CTGCTTGGCACGCTACCCTCATCATCTTACTCATCTTAAGCCCGAGCCATGGATCAACTAGGAGCCCATATAAATGAGGCTCAGTAGGGC
TGCACATAATCTCCAAACAATTCTTTATTCAGTGTTTTGCTTGTGTTTGCATGTTGCTATGATGGACAGGTCCCCCTCCTCCATTCTTGC
CCTCTGGAGAAGTGGTTCCTGCAGTGTAGAGATATGAACAGGGTATGGTAGGATTGGGGAAAGGGGAGAGAGAAGCAGTAGATACACTCC
TTATCCTCCCCAAATTTTAAGCTCTATTTCTGTGCCCTAGTCCTAGACACACATTAGACTCAGGGAGTTTTGTCTGAAGACCAGGTCCCA
CTGCCCCCTGGCTGAAGAGTCTGCTTTAAATGGGAAAACAACGTAGGAGCAGGGGTTTTTAGGCACTTTCAGTATTCTCAGGTGTTCTTC
GTTCTGGCCCTTCCAGGGTAATTAGGAAGGCAGAACAAGACAGATGAGCTCCTGCCTGCTCTGAGACAAGAAGGGTGGGGTCTCATTAGC
TTTGCAACAGGAAACATCCTGTTTTATGGTAGTGGGGTCAGGAATGTAGGAACTGGTATCCATTCTGCCAATTCCACCACCCATTCAGTT
TGCTTATCCCTACAGAACAGTGACTGAGGTTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCAAATTTCCATGTATTTTCTGCCATTTTTCA
GGGTCTAAGATTGGTCATACATTCCCAATTTACTCTCAGTTCCAGTCAAGCTGGTTGCTCTGAAAGTAACCCAGCTTGTTGCTCTAAAAT
ACCTCAGTAGCCTGAGTGTTATACTAGAGATCTAAAGGGTTAACAGGATAGGGTGGAAAGGTTAGAGACTCCTAGAAATCTCTGGTCACC
GTGATCTTCGGCCTCATTCTAATACCTGTTCTTTGGACAGTCTTTTTCCTTTGGTGCTCTCTTGCCTTTAGCTACCTTCTCTAATATGTA
TGCTACCATCACTAATAAAGTGATGGGAATGGGTTTGAGAGTCGTAATTTATATTAAAAAGTTGTTGGACTTTTAAATACATTTTTTCAA

>2927_2927_2_AGPAT2-CDC42SE1_AGPAT2_chr9_139571413_ENST00000371694_CDC42SE1_chr1_151027602_ENST00000439374_length(amino acids)=225AA_BP=164
MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEAR
PCVIVSNHQSILDMMGLMEVLPERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENKKKRRRIDRTMIGEPM

--------------------------------------------------------------
>2927_2927_3_AGPAT2-CDC42SE1_AGPAT2_chr9_139571413_ENST00000371694_CDC42SE1_chr1_151027602_ENST00000540998_length(transcript)=3090nt_BP=533nt
CGGGAGCGAGCTGGCGGCGCCGTCGGGCGCCGGGCCGGGCCATGGAGCTGTGGCCGTGTCTGGCCGCGGCGCTGCTGTTGCTGCTGCTGC
TGGTGCAGCTGAGCCGCGCGGCCGAGTTCTACGCCAAGGTCGCCCTGTACTGCGCGCTGTGCTTCACGGTGTCCGCCGTGGCCTCGCTCG
TCTGCCTGCTGCGCCACGGCGGCCGGACGGTGGAGAACATGAGCATCATCGGCTGGTTCGTGCGAAGCTTCAAGTACTTTTACGGGCTCC
GCTTCGAGGTGCGGGACCCGCGCAGGCTGCAGGAGGCCCGTCCCTGTGTCATCGTCTCCAACCACCAGAGCATCCTGGACATGATGGGCC
TCATGGAGGTCCTTCCGGAGCGCTGCGTGCAGATCGCCAAGCGGGAGCTGCTCTTCCTGGGGCCCGTGGGCCTCATCATGTACCTCGGGG
GCGTCTTCTTCATCAACCGGCAGCGCTCTAGCACTGCCATGACAGTGATGGCCGACCTGGGCGAGCGCATGGTCAGGGAGAACAAGAAGA
AGAGAAGACGGATTGACCGGACCATGATTGGGGAACCAATGAATTTTGTTCACCTGACTCACATTGGCTCAGGGGAGATGGGGGCCGGAG
ATGGACTTGCCATGACAGGTGCAGTTCAGGAGCAGATGAGATCCAAGGGAAACCGAGATAGGCCATGGAGCAATTCTAGGGGCTTATAGC
TCCAATAATGGAATGGTTCTGCCATCTTGAAACCCCCATTCTGTTTCCAGCCCAGAAGAAATGCTGCCCCTACCAGATCCCTCCTTGAAC
CAGTGATCTAAGGACCCCTCTTTTCCCTATCTGCCTAACAGTGCCTCACAAGGCTTGGGGGCTGGACTCCCTCTACTCCCTCTGGCCATA
GCCCCTCCTGGAGATGGGGTCAAGGCAGCAGGACTGATCAAGTGACTACTGGTTAGCCAGAGGAGCTCAGCTGAAGCCCTGGAAACCCTC
AGGTCTGAGATAGGAGTTCTCTAGGAACCTGGAATGAGTTCCTGTCTCCTGAATGATGGTCTGGGTGCCACCTGTTTTTAAACTCTTAAA
CCTGGAACTCCTTAAATGGGGTAGGTGGGTGAGATTATCAAAGCTGAAGCTGGCTTTGCTGAGAAGCTCCCTACCTCCCTGCCCTTCTCC
TCCTTCCTGCTGGAATGAACTAAAGCAGATGTCAAGCAGGGGCTGGTGGGGGTGCCTACTCCCTTTTCCACTCTATCTTTAGATTTCAAA
CCTTAGGCTTACAGCCCCTCAATATCTCTCTGCTAACACCAGTGTCTCTTTCTAGTTAGGCCTCTAATCTTCTGTTTCTGTTTACCAGCT
TCCCAGCAACTTTCCTTTTTTAAAATATTAAAAATTTAATTCAGGTTCTCTTAATTATCCTCATCCTGCTGTTGCCTCCGCCCTTAACTC
TATCCCTATTAGGAACCTTGTTTCCCACCGAATAAGAGTTAAGGTAAGAGGTAGCTCTTCACCTGATGACATTCCATTTAAGTTTTGGGG
CATCTTTCCTGCCCTCTGCCAACCTCCCTGCTGGCCCAGGTGAGAGGAGGAAGAGGGGTCTGGAAAGAAACCCAGAATGCGGCAGAACTA
GGAGTAAGTCCATCTCAAGGTGGACTTCTGATCATTGAGGATGGTGAGATAAATAGGTTGAAAACAATCATCTGTGAGTTTAGGAGTCTT
AAGATCCTCACAGCACGGGAGCAGGGAGAGGCTCTAGAACAAGGTTTCACAACCGAGATGCCTTTGACATTTTGGGCTGAAGTGTTCTTT
GTAAGGAAAACCTGTTTCCTATTTTGTGCATTACAGGATATTTAGCAGCAACCCTGGCCCACTCTAGTTATGACAACCAAAAATGTCTCT
ATACATTGCCAGATTTCTCCTAGGGGGCAAAATCGCCTCCATTTGAGAACCACAACTCTAAAGTCAAGATATTTTTCTCTGAAGTGATTT
CTGCTTGGCACGCTACCCTCATCATCTTACTCATCTTAAGCCCGAGCCATGGATCAACTAGGAGCCCATATAAATGAGGCTCAGTAGGGC
TGCACATAATCTCCAAACAATTCTTTATTCAGTGTTTTGCTTGTGTTTGCATGTTGCTATGATGGACAGGTCCCCCTCCTCCATTCTTGC
CCTCTGGAGAAGTGGTTCCTGCAGTGTAGAGATATGAACAGGGTATGGTAGGATTGGGGAAAGGGGAGAGAGAAGCAGTAGATACACTCC
TTATCCTCCCCAAATTTTAAGCTCTATTTCTGTGCCCTAGTCCTAGACACACATTAGACTCAGGGAGTTTTGTCTGAAGACCAGGTCCCA
CTGCCCCCTGGCTGAAGAGTCTGCTTTAAATGGGAAAACAACGTAGGAGCAGGGGTTTTTAGGCACTTTCAGTATTCTCAGGTGTTCTTC
GTTCTGGCCCTTCCAGGGTAATTAGGAAGGCAGAACAAGACAGATGAGCTCCTGCCTGCTCTGAGACAAGAAGGGTGGGGTCTCATTAGC
TTTGCAACAGGAAACATCCTGTTTTATGGTAGTGGGGTCAGGAATGTAGGAACTGGTATCCATTCTGCCAATTCCACCACCCATTCAGTT
TGCTTATCCCTACAGAACAGTGACTGAGGTTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCAAATTTCCATGTATTTTCTGCCATTTTTCA
GGGTCTAAGATTGGTCATACATTCCCAATTTACTCTCAGTTCCAGTCAAGCTGGTTGCTCTGAAAGTAACCCAGCTTGTTGCTCTAAAAT
ACCTCAGTAGCCTGAGTGTTATACTAGAGATCTAAAGGGTTAACAGGATAGGGTGGAAAGGTTAGAGACTCCTAGAAATCTCTGGTCACC
GTGATCTTCGGCCTCATTCTAATACCTGTTCTTTGGACAGTCTTTTTCCTTTGGTGCTCTCTTGCCTTTAGCTACCTTCTCTAATATGTA
TGCTACCATCACTAATAAAGTGATGGGAATGGGTTTGAGAGTCGTAATTTATATTAAAAAGTTGTTGGACTTTTAAATACATTTTTTCAA

>2927_2927_3_AGPAT2-CDC42SE1_AGPAT2_chr9_139571413_ENST00000371694_CDC42SE1_chr1_151027602_ENST00000540998_length(amino acids)=225AA_BP=164
MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEAR
PCVIVSNHQSILDMMGLMEVLPERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENKKKRRRIDRTMIGEPM

--------------------------------------------------------------
>2927_2927_4_AGPAT2-CDC42SE1_AGPAT2_chr9_139571413_ENST00000371696_CDC42SE1_chr1_151027602_ENST00000357235_length(transcript)=3115nt_BP=558nt
CGCGGGGGAGAAGCGGGAGCGGGAGCGGGAGCGAGCTGGCGGCGCCGTCGGGCGCCGGGCCGGGCCATGGAGCTGTGGCCGTGTCTGGCC
GCGGCGCTGCTGTTGCTGCTGCTGCTGGTGCAGCTGAGCCGCGCGGCCGAGTTCTACGCCAAGGTCGCCCTGTACTGCGCGCTGTGCTTC
ACGGTGTCCGCCGTGGCCTCGCTCGTCTGCCTGCTGCGCCACGGCGGCCGGACGGTGGAGAACATGAGCATCATCGGCTGGTTCGTGCGA
AGCTTCAAGTACTTTTACGGGCTCCGCTTCGAGGTGCGGGACCCGCGCAGGCTGCAGGAGGCCCGTCCCTGTGTCATCGTCTCCAACCAC
CAGAGCATCCTGGACATGATGGGCCTCATGGAGGTCCTTCCGGAGCGCTGCGTGCAGATCGCCAAGCGGGAGCTGCTCTTCCTGGGGCCC
GTGGGCCTCATCATGTACCTCGGGGGCGTCTTCTTCATCAACCGGCAGCGCTCTAGCACTGCCATGACAGTGATGGCCGACCTGGGCGAG
CGCATGGTCAGGGAGAACAAGAAGAAGAGAAGACGGATTGACCGGACCATGATTGGGGAACCAATGAATTTTGTTCACCTGACTCACATT
GGCTCAGGGGAGATGGGGGCCGGAGATGGACTTGCCATGACAGGTGCAGTTCAGGAGCAGATGAGATCCAAGGGAAACCGAGATAGGCCA
TGGAGCAATTCTAGGGGCTTATAGCTCCAATAATGGAATGGTTCTGCCATCTTGAAACCCCCATTCTGTTTCCAGCCCAGAAGAAATGCT
GCCCCTACCAGATCCCTCCTTGAACCAGTGATCTAAGGACCCCTCTTTTCCCTATCTGCCTAACAGTGCCTCACAAGGCTTGGGGGCTGG
ACTCCCTCTACTCCCTCTGGCCATAGCCCCTCCTGGAGATGGGGTCAAGGCAGCAGGACTGATCAAGTGACTACTGGTTAGCCAGAGGAG
CTCAGCTGAAGCCCTGGAAACCCTCAGGTCTGAGATAGGAGTTCTCTAGGAACCTGGAATGAGTTCCTGTCTCCTGAATGATGGTCTGGG
TGCCACCTGTTTTTAAACTCTTAAACCTGGAACTCCTTAAATGGGGTAGGTGGGTGAGATTATCAAAGCTGAAGCTGGCTTTGCTGAGAA
GCTCCCTACCTCCCTGCCCTTCTCCTCCTTCCTGCTGGAATGAACTAAAGCAGATGTCAAGCAGGGGCTGGTGGGGGTGCCTACTCCCTT
TTCCACTCTATCTTTAGATTTCAAACCTTAGGCTTACAGCCCCTCAATATCTCTCTGCTAACACCAGTGTCTCTTTCTAGTTAGGCCTCT
AATCTTCTGTTTCTGTTTACCAGCTTCCCAGCAACTTTCCTTTTTTAAAATATTAAAAATTTAATTCAGGTTCTCTTAATTATCCTCATC
CTGCTGTTGCCTCCGCCCTTAACTCTATCCCTATTAGGAACCTTGTTTCCCACCGAATAAGAGTTAAGGTAAGAGGTAGCTCTTCACCTG
ATGACATTCCATTTAAGTTTTGGGGCATCTTTCCTGCCCTCTGCCAACCTCCCTGCTGGCCCAGGTGAGAGGAGGAAGAGGGGTCTGGAA
AGAAACCCAGAATGCGGCAGAACTAGGAGTAAGTCCATCTCAAGGTGGACTTCTGATCATTGAGGATGGTGAGATAAATAGGTTGAAAAC
AATCATCTGTGAGTTTAGGAGTCTTAAGATCCTCACAGCACGGGAGCAGGGAGAGGCTCTAGAACAAGGTTTCACAACCGAGATGCCTTT
GACATTTTGGGCTGAAGTGTTCTTTGTAAGGAAAACCTGTTTCCTATTTTGTGCATTACAGGATATTTAGCAGCAACCCTGGCCCACTCT
AGTTATGACAACCAAAAATGTCTCTATACATTGCCAGATTTCTCCTAGGGGGCAAAATCGCCTCCATTTGAGAACCACAACTCTAAAGTC
AAGATATTTTTCTCTGAAGTGATTTCTGCTTGGCACGCTACCCTCATCATCTTACTCATCTTAAGCCCGAGCCATGGATCAACTAGGAGC
CCATATAAATGAGGCTCAGTAGGGCTGCACATAATCTCCAAACAATTCTTTATTCAGTGTTTTGCTTGTGTTTGCATGTTGCTATGATGG
ACAGGTCCCCCTCCTCCATTCTTGCCCTCTGGAGAAGTGGTTCCTGCAGTGTAGAGATATGAACAGGGTATGGTAGGATTGGGGAAAGGG
GAGAGAGAAGCAGTAGATACACTCCTTATCCTCCCCAAATTTTAAGCTCTATTTCTGTGCCCTAGTCCTAGACACACATTAGACTCAGGG
AGTTTTGTCTGAAGACCAGGTCCCACTGCCCCCTGGCTGAAGAGTCTGCTTTAAATGGGAAAACAACGTAGGAGCAGGGGTTTTTAGGCA
CTTTCAGTATTCTCAGGTGTTCTTCGTTCTGGCCCTTCCAGGGTAATTAGGAAGGCAGAACAAGACAGATGAGCTCCTGCCTGCTCTGAG
ACAAGAAGGGTGGGGTCTCATTAGCTTTGCAACAGGAAACATCCTGTTTTATGGTAGTGGGGTCAGGAATGTAGGAACTGGTATCCATTC
TGCCAATTCCACCACCCATTCAGTTTGCTTATCCCTACAGAACAGTGACTGAGGTTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCAAATT
TCCATGTATTTTCTGCCATTTTTCAGGGTCTAAGATTGGTCATACATTCCCAATTTACTCTCAGTTCCAGTCAAGCTGGTTGCTCTGAAA
GTAACCCAGCTTGTTGCTCTAAAATACCTCAGTAGCCTGAGTGTTATACTAGAGATCTAAAGGGTTAACAGGATAGGGTGGAAAGGTTAG
AGACTCCTAGAAATCTCTGGTCACCGTGATCTTCGGCCTCATTCTAATACCTGTTCTTTGGACAGTCTTTTTCCTTTGGTGCTCTCTTGC
CTTTAGCTACCTTCTCTAATATGTATGCTACCATCACTAATAAAGTGATGGGAATGGGTTTGAGAGTCGTAATTTATATTAAAAAGTTGT

>2927_2927_4_AGPAT2-CDC42SE1_AGPAT2_chr9_139571413_ENST00000371696_CDC42SE1_chr1_151027602_ENST00000357235_length(amino acids)=225AA_BP=164
MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEAR
PCVIVSNHQSILDMMGLMEVLPERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENKKKRRRIDRTMIGEPM

--------------------------------------------------------------
>2927_2927_5_AGPAT2-CDC42SE1_AGPAT2_chr9_139571413_ENST00000371696_CDC42SE1_chr1_151027602_ENST00000439374_length(transcript)=3117nt_BP=558nt
CGCGGGGGAGAAGCGGGAGCGGGAGCGGGAGCGAGCTGGCGGCGCCGTCGGGCGCCGGGCCGGGCCATGGAGCTGTGGCCGTGTCTGGCC
GCGGCGCTGCTGTTGCTGCTGCTGCTGGTGCAGCTGAGCCGCGCGGCCGAGTTCTACGCCAAGGTCGCCCTGTACTGCGCGCTGTGCTTC
ACGGTGTCCGCCGTGGCCTCGCTCGTCTGCCTGCTGCGCCACGGCGGCCGGACGGTGGAGAACATGAGCATCATCGGCTGGTTCGTGCGA
AGCTTCAAGTACTTTTACGGGCTCCGCTTCGAGGTGCGGGACCCGCGCAGGCTGCAGGAGGCCCGTCCCTGTGTCATCGTCTCCAACCAC
CAGAGCATCCTGGACATGATGGGCCTCATGGAGGTCCTTCCGGAGCGCTGCGTGCAGATCGCCAAGCGGGAGCTGCTCTTCCTGGGGCCC
GTGGGCCTCATCATGTACCTCGGGGGCGTCTTCTTCATCAACCGGCAGCGCTCTAGCACTGCCATGACAGTGATGGCCGACCTGGGCGAG
CGCATGGTCAGGGAGAACAAGAAGAAGAGAAGACGGATTGACCGGACCATGATTGGGGAACCAATGAATTTTGTTCACCTGACTCACATT
GGCTCAGGGGAGATGGGGGCCGGAGATGGACTTGCCATGACAGGTGCAGTTCAGGAGCAGATGAGATCCAAGGGAAACCGAGATAGGCCA
TGGAGCAATTCTAGGGGCTTATAGCTCCAATAATGGAATGGTTCTGCCATCTTGAAACCCCCATTCTGTTTCCAGCCCAGAAGAAATGCT
GCCCCTACCAGATCCCTCCTTGAACCAGTGATCTAAGGACCCCTCTTTTCCCTATCTGCCTAACAGTGCCTCACAAGGCTTGGGGGCTGG
ACTCCCTCTACTCCCTCTGGCCATAGCCCCTCCTGGAGATGGGGTCAAGGCAGCAGGACTGATCAAGTGACTACTGGTTAGCCAGAGGAG
CTCAGCTGAAGCCCTGGAAACCCTCAGGTCTGAGATAGGAGTTCTCTAGGAACCTGGAATGAGTTCCTGTCTCCTGAATGATGGTCTGGG
TGCCACCTGTTTTTAAACTCTTAAACCTGGAACTCCTTAAATGGGGTAGGTGGGTGAGATTATCAAAGCTGAAGCTGGCTTTGCTGAGAA
GCTCCCTACCTCCCTGCCCTTCTCCTCCTTCCTGCTGGAATGAACTAAAGCAGATGTCAAGCAGGGGCTGGTGGGGGTGCCTACTCCCTT
TTCCACTCTATCTTTAGATTTCAAACCTTAGGCTTACAGCCCCTCAATATCTCTCTGCTAACACCAGTGTCTCTTTCTAGTTAGGCCTCT
AATCTTCTGTTTCTGTTTACCAGCTTCCCAGCAACTTTCCTTTTTTAAAATATTAAAAATTTAATTCAGGTTCTCTTAATTATCCTCATC
CTGCTGTTGCCTCCGCCCTTAACTCTATCCCTATTAGGAACCTTGTTTCCCACCGAATAAGAGTTAAGGTAAGAGGTAGCTCTTCACCTG
ATGACATTCCATTTAAGTTTTGGGGCATCTTTCCTGCCCTCTGCCAACCTCCCTGCTGGCCCAGGTGAGAGGAGGAAGAGGGGTCTGGAA
AGAAACCCAGAATGCGGCAGAACTAGGAGTAAGTCCATCTCAAGGTGGACTTCTGATCATTGAGGATGGTGAGATAAATAGGTTGAAAAC
AATCATCTGTGAGTTTAGGAGTCTTAAGATCCTCACAGCACGGGAGCAGGGAGAGGCTCTAGAACAAGGTTTCACAACCGAGATGCCTTT
GACATTTTGGGCTGAAGTGTTCTTTGTAAGGAAAACCTGTTTCCTATTTTGTGCATTACAGGATATTTAGCAGCAACCCTGGCCCACTCT
AGTTATGACAACCAAAAATGTCTCTATACATTGCCAGATTTCTCCTAGGGGGCAAAATCGCCTCCATTTGAGAACCACAACTCTAAAGTC
AAGATATTTTTCTCTGAAGTGATTTCTGCTTGGCACGCTACCCTCATCATCTTACTCATCTTAAGCCCGAGCCATGGATCAACTAGGAGC
CCATATAAATGAGGCTCAGTAGGGCTGCACATAATCTCCAAACAATTCTTTATTCAGTGTTTTGCTTGTGTTTGCATGTTGCTATGATGG
ACAGGTCCCCCTCCTCCATTCTTGCCCTCTGGAGAAGTGGTTCCTGCAGTGTAGAGATATGAACAGGGTATGGTAGGATTGGGGAAAGGG
GAGAGAGAAGCAGTAGATACACTCCTTATCCTCCCCAAATTTTAAGCTCTATTTCTGTGCCCTAGTCCTAGACACACATTAGACTCAGGG
AGTTTTGTCTGAAGACCAGGTCCCACTGCCCCCTGGCTGAAGAGTCTGCTTTAAATGGGAAAACAACGTAGGAGCAGGGGTTTTTAGGCA
CTTTCAGTATTCTCAGGTGTTCTTCGTTCTGGCCCTTCCAGGGTAATTAGGAAGGCAGAACAAGACAGATGAGCTCCTGCCTGCTCTGAG
ACAAGAAGGGTGGGGTCTCATTAGCTTTGCAACAGGAAACATCCTGTTTTATGGTAGTGGGGTCAGGAATGTAGGAACTGGTATCCATTC
TGCCAATTCCACCACCCATTCAGTTTGCTTATCCCTACAGAACAGTGACTGAGGTTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCAAATT
TCCATGTATTTTCTGCCATTTTTCAGGGTCTAAGATTGGTCATACATTCCCAATTTACTCTCAGTTCCAGTCAAGCTGGTTGCTCTGAAA
GTAACCCAGCTTGTTGCTCTAAAATACCTCAGTAGCCTGAGTGTTATACTAGAGATCTAAAGGGTTAACAGGATAGGGTGGAAAGGTTAG
AGACTCCTAGAAATCTCTGGTCACCGTGATCTTCGGCCTCATTCTAATACCTGTTCTTTGGACAGTCTTTTTCCTTTGGTGCTCTCTTGC
CTTTAGCTACCTTCTCTAATATGTATGCTACCATCACTAATAAAGTGATGGGAATGGGTTTGAGAGTCGTAATTTATATTAAAAAGTTGT

>2927_2927_5_AGPAT2-CDC42SE1_AGPAT2_chr9_139571413_ENST00000371696_CDC42SE1_chr1_151027602_ENST00000439374_length(amino acids)=225AA_BP=164
MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEAR
PCVIVSNHQSILDMMGLMEVLPERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENKKKRRRIDRTMIGEPM

--------------------------------------------------------------
>2927_2927_6_AGPAT2-CDC42SE1_AGPAT2_chr9_139571413_ENST00000371696_CDC42SE1_chr1_151027602_ENST00000540998_length(transcript)=3115nt_BP=558nt
CGCGGGGGAGAAGCGGGAGCGGGAGCGGGAGCGAGCTGGCGGCGCCGTCGGGCGCCGGGCCGGGCCATGGAGCTGTGGCCGTGTCTGGCC
GCGGCGCTGCTGTTGCTGCTGCTGCTGGTGCAGCTGAGCCGCGCGGCCGAGTTCTACGCCAAGGTCGCCCTGTACTGCGCGCTGTGCTTC
ACGGTGTCCGCCGTGGCCTCGCTCGTCTGCCTGCTGCGCCACGGCGGCCGGACGGTGGAGAACATGAGCATCATCGGCTGGTTCGTGCGA
AGCTTCAAGTACTTTTACGGGCTCCGCTTCGAGGTGCGGGACCCGCGCAGGCTGCAGGAGGCCCGTCCCTGTGTCATCGTCTCCAACCAC
CAGAGCATCCTGGACATGATGGGCCTCATGGAGGTCCTTCCGGAGCGCTGCGTGCAGATCGCCAAGCGGGAGCTGCTCTTCCTGGGGCCC
GTGGGCCTCATCATGTACCTCGGGGGCGTCTTCTTCATCAACCGGCAGCGCTCTAGCACTGCCATGACAGTGATGGCCGACCTGGGCGAG
CGCATGGTCAGGGAGAACAAGAAGAAGAGAAGACGGATTGACCGGACCATGATTGGGGAACCAATGAATTTTGTTCACCTGACTCACATT
GGCTCAGGGGAGATGGGGGCCGGAGATGGACTTGCCATGACAGGTGCAGTTCAGGAGCAGATGAGATCCAAGGGAAACCGAGATAGGCCA
TGGAGCAATTCTAGGGGCTTATAGCTCCAATAATGGAATGGTTCTGCCATCTTGAAACCCCCATTCTGTTTCCAGCCCAGAAGAAATGCT
GCCCCTACCAGATCCCTCCTTGAACCAGTGATCTAAGGACCCCTCTTTTCCCTATCTGCCTAACAGTGCCTCACAAGGCTTGGGGGCTGG
ACTCCCTCTACTCCCTCTGGCCATAGCCCCTCCTGGAGATGGGGTCAAGGCAGCAGGACTGATCAAGTGACTACTGGTTAGCCAGAGGAG
CTCAGCTGAAGCCCTGGAAACCCTCAGGTCTGAGATAGGAGTTCTCTAGGAACCTGGAATGAGTTCCTGTCTCCTGAATGATGGTCTGGG
TGCCACCTGTTTTTAAACTCTTAAACCTGGAACTCCTTAAATGGGGTAGGTGGGTGAGATTATCAAAGCTGAAGCTGGCTTTGCTGAGAA
GCTCCCTACCTCCCTGCCCTTCTCCTCCTTCCTGCTGGAATGAACTAAAGCAGATGTCAAGCAGGGGCTGGTGGGGGTGCCTACTCCCTT
TTCCACTCTATCTTTAGATTTCAAACCTTAGGCTTACAGCCCCTCAATATCTCTCTGCTAACACCAGTGTCTCTTTCTAGTTAGGCCTCT
AATCTTCTGTTTCTGTTTACCAGCTTCCCAGCAACTTTCCTTTTTTAAAATATTAAAAATTTAATTCAGGTTCTCTTAATTATCCTCATC
CTGCTGTTGCCTCCGCCCTTAACTCTATCCCTATTAGGAACCTTGTTTCCCACCGAATAAGAGTTAAGGTAAGAGGTAGCTCTTCACCTG
ATGACATTCCATTTAAGTTTTGGGGCATCTTTCCTGCCCTCTGCCAACCTCCCTGCTGGCCCAGGTGAGAGGAGGAAGAGGGGTCTGGAA
AGAAACCCAGAATGCGGCAGAACTAGGAGTAAGTCCATCTCAAGGTGGACTTCTGATCATTGAGGATGGTGAGATAAATAGGTTGAAAAC
AATCATCTGTGAGTTTAGGAGTCTTAAGATCCTCACAGCACGGGAGCAGGGAGAGGCTCTAGAACAAGGTTTCACAACCGAGATGCCTTT
GACATTTTGGGCTGAAGTGTTCTTTGTAAGGAAAACCTGTTTCCTATTTTGTGCATTACAGGATATTTAGCAGCAACCCTGGCCCACTCT
AGTTATGACAACCAAAAATGTCTCTATACATTGCCAGATTTCTCCTAGGGGGCAAAATCGCCTCCATTTGAGAACCACAACTCTAAAGTC
AAGATATTTTTCTCTGAAGTGATTTCTGCTTGGCACGCTACCCTCATCATCTTACTCATCTTAAGCCCGAGCCATGGATCAACTAGGAGC
CCATATAAATGAGGCTCAGTAGGGCTGCACATAATCTCCAAACAATTCTTTATTCAGTGTTTTGCTTGTGTTTGCATGTTGCTATGATGG
ACAGGTCCCCCTCCTCCATTCTTGCCCTCTGGAGAAGTGGTTCCTGCAGTGTAGAGATATGAACAGGGTATGGTAGGATTGGGGAAAGGG
GAGAGAGAAGCAGTAGATACACTCCTTATCCTCCCCAAATTTTAAGCTCTATTTCTGTGCCCTAGTCCTAGACACACATTAGACTCAGGG
AGTTTTGTCTGAAGACCAGGTCCCACTGCCCCCTGGCTGAAGAGTCTGCTTTAAATGGGAAAACAACGTAGGAGCAGGGGTTTTTAGGCA
CTTTCAGTATTCTCAGGTGTTCTTCGTTCTGGCCCTTCCAGGGTAATTAGGAAGGCAGAACAAGACAGATGAGCTCCTGCCTGCTCTGAG
ACAAGAAGGGTGGGGTCTCATTAGCTTTGCAACAGGAAACATCCTGTTTTATGGTAGTGGGGTCAGGAATGTAGGAACTGGTATCCATTC
TGCCAATTCCACCACCCATTCAGTTTGCTTATCCCTACAGAACAGTGACTGAGGTTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCAAATT
TCCATGTATTTTCTGCCATTTTTCAGGGTCTAAGATTGGTCATACATTCCCAATTTACTCTCAGTTCCAGTCAAGCTGGTTGCTCTGAAA
GTAACCCAGCTTGTTGCTCTAAAATACCTCAGTAGCCTGAGTGTTATACTAGAGATCTAAAGGGTTAACAGGATAGGGTGGAAAGGTTAG
AGACTCCTAGAAATCTCTGGTCACCGTGATCTTCGGCCTCATTCTAATACCTGTTCTTTGGACAGTCTTTTTCCTTTGGTGCTCTCTTGC
CTTTAGCTACCTTCTCTAATATGTATGCTACCATCACTAATAAAGTGATGGGAATGGGTTTGAGAGTCGTAATTTATATTAAAAAGTTGT

>2927_2927_6_AGPAT2-CDC42SE1_AGPAT2_chr9_139571413_ENST00000371696_CDC42SE1_chr1_151027602_ENST00000540998_length(amino acids)=225AA_BP=164
MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEAR
PCVIVSNHQSILDMMGLMEVLPERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENKKKRRRIDRTMIGEPM

--------------------------------------------------------------

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Fusion Gene PPI Analysis for AGPAT2-CDC42SE1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AGPAT2-CDC42SE1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AGPAT2-CDC42SE1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneAGPAT2C1720862Congenital Generalized Lipodystrophy Type 13CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneAGPAT2C0023787Lipodystrophy2GENOMICS_ENGLAND
TgeneC0023893Liver Cirrhosis, Experimental1CTD_human