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in Kim Lab

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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ASCC3-SIM1 (FusionGDB2 ID:HG10973TG6492)

Fusion Gene Summary for ASCC3-SIM1

check button Fusion gene summary
Fusion gene informationFusion gene name: ASCC3-SIM1
Fusion gene ID: hg10973tg6492
HgeneTgene
Gene symbol

ASCC3

SIM1

Gene ID

10973

6492

Gene nameactivating signal cointegrator 1 complex subunit 3SIM bHLH transcription factor 1
SynonymsASC1p200|HELIC1|RNAHbHLHe14
Cytomap('ASCC3')('SIM1')

6q16.3

6q16.3

Type of geneprotein-codingprotein-coding
Descriptionactivating signal cointegrator 1 complex subunit 3ASC-1 complex subunit P200RNA helicase familyhelicase, ATP binding 1trip4 complex subunit p200single-minded homolog 1class E basic helix-loop-helix protein 14single-minded family bHLH transcription factor 1
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000369162, ENST00000369143, 
ENST00000522650, 		ENST00000369143, 
ENST00000522650, ENST00000369162, 
Fusion gene scores* DoF score13 X 16 X 12=24964 X 4 X 3=48
# samples 145
** MAII scorelog2(14/2496*10)=-4.15611920191728
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/48*10)=0.0588936890535686
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: ASCC3 [Title/Abstract] AND SIM1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointASCC3(101037510)-SIM1(100901720), # samples:1
Anticipated loss of major functional domain due to fusion event.ASCC3-SIM1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ASCC3-SIM1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ASCC3-SIM1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ASCC3-SIM1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
SIM1-ASCC3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
SIM1-ASCC3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneASCC3

GO:0006307

DNA dealkylation involved in DNA repair

22055184

HgeneASCC3

GO:0032508

DNA duplex unwinding

22055184


check buttonFusion gene breakpoints across ASCC3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across SIM1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-85-7843-01AASCC3chr6

101037510

-SIM1chr6

100901720

-


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Fusion Gene ORF analysis for ASCC3-SIM1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000369162ENST00000262901ASCC3chr6

101037510

-SIM1chr6

100901720

-
In-frameENST00000369162ENST00000369208ASCC3chr6

101037510

-SIM1chr6

100901720

-
intron-3CDSENST00000369143ENST00000262901ASCC3chr6

101037510

-SIM1chr6

100901720

-
intron-3CDSENST00000369143ENST00000369208ASCC3chr6

101037510

-SIM1chr6

100901720

-
intron-3CDSENST00000522650ENST00000262901ASCC3chr6

101037510

-SIM1chr6

100901720

-
intron-3CDSENST00000522650ENST00000369208ASCC3chr6

101037510

-SIM1chr6

100901720

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000369162ASCC3chr6101037510-ENST00000369208SIM1chr6100901720-13367589534560051886
ENST00000369162ASCC3chr6101037510-ENST00000262901SIM1chr6100901720-9510589534560051886

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000369162ENST00000369208ASCC3chr6101037510-SIM1chr6100901720-8.74E-050.9999126
ENST00000369162ENST00000262901ASCC3chr6101037510-SIM1chr6100901720-0.0003574860.9996425

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Fusion Genomic Features for ASCC3-SIM1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ASCC3-SIM1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:101037510/chr6:100901720)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneASCC3chr6:101037510chr6:100901720ENST00000369162-364218_7918502203.0Coiled coilOntology_term=ECO:0000255
HgeneASCC3chr6:101037510chr6:100901720ENST00000369162-3642328_35618502203.0Coiled coilOntology_term=ECO:0000255
HgeneASCC3chr6:101037510chr6:100901720ENST00000369162-36421336_151118502203.0DomainHelicase ATP-binding 2
HgeneASCC3chr6:101037510chr6:100901720ENST00000369162-36421544_173918502203.0DomainHelicase C-terminal 2
HgeneASCC3chr6:101037510chr6:100901720ENST00000369162-3642486_66918502203.0DomainHelicase ATP-binding 1
HgeneASCC3chr6:101037510chr6:100901720ENST00000369162-3642728_91418502203.0DomainHelicase C-terminal 1
HgeneASCC3chr6:101037510chr6:100901720ENST00000369162-3642978_128718502203.0DomainNote=SEC63 1
HgeneASCC3chr6:101037510chr6:100901720ENST00000369162-36421453_145618502203.0MotifNote=DEIH box
HgeneASCC3chr6:101037510chr6:100901720ENST00000369162-3642611_61418502203.0MotifNote=DEVH box
HgeneASCC3chr6:101037510chr6:100901720ENST00000369162-36421349_135618502203.0Nucleotide bindingATP
HgeneASCC3chr6:101037510chr6:100901720ENST00000369162-3642499_50618502203.0Nucleotide bindingATP
TgeneSIM1chr6:101037510chr6:100901720ENST00000262901011218_28858767.0DomainPAS 2
TgeneSIM1chr6:101037510chr6:100901720ENST00000262901011292_33558767.0DomainNote=PAC
TgeneSIM1chr6:101037510chr6:100901720ENST00000262901011336_76658767.0DomainSingle-minded C-terminal
TgeneSIM1chr6:101037510chr6:100901720ENST0000026290101177_14758767.0DomainPAS 1
TgeneSIM1chr6:101037510chr6:100901720ENST00000369208112218_28858767.0DomainPAS 2
TgeneSIM1chr6:101037510chr6:100901720ENST00000369208112292_33558767.0DomainNote=PAC
TgeneSIM1chr6:101037510chr6:100901720ENST00000369208112336_76658767.0DomainSingle-minded C-terminal
TgeneSIM1chr6:101037510chr6:100901720ENST0000036920811277_14758767.0DomainPAS 1
TgeneSIM1chr6:101037510chr6:100901720ENST00000262901011368_38758767.0MotifNuclear localization signal
TgeneSIM1chr6:101037510chr6:100901720ENST00000369208112368_38758767.0MotifNuclear localization signal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneASCC3chr6:101037510chr6:100901720ENST00000369143-1418_790112.0Coiled coilOntology_term=ECO:0000255
HgeneASCC3chr6:101037510chr6:100901720ENST00000369143-14328_3560112.0Coiled coilOntology_term=ECO:0000255
HgeneASCC3chr6:101037510chr6:100901720ENST00000522650-11318_790732.0Coiled coilOntology_term=ECO:0000255
HgeneASCC3chr6:101037510chr6:100901720ENST00000522650-113328_3560732.0Coiled coilOntology_term=ECO:0000255
HgeneASCC3chr6:101037510chr6:100901720ENST00000369143-141336_15110112.0DomainHelicase ATP-binding 2
HgeneASCC3chr6:101037510chr6:100901720ENST00000369143-141544_17390112.0DomainHelicase C-terminal 2
HgeneASCC3chr6:101037510chr6:100901720ENST00000369143-141812_21760112.0DomainNote=SEC63 2
HgeneASCC3chr6:101037510chr6:100901720ENST00000369143-14486_6690112.0DomainHelicase ATP-binding 1
HgeneASCC3chr6:101037510chr6:100901720ENST00000369143-14728_9140112.0DomainHelicase C-terminal 1
HgeneASCC3chr6:101037510chr6:100901720ENST00000369143-14978_12870112.0DomainNote=SEC63 1
HgeneASCC3chr6:101037510chr6:100901720ENST00000369162-36421812_217618502203.0DomainNote=SEC63 2
HgeneASCC3chr6:101037510chr6:100901720ENST00000522650-1131336_15110732.0DomainHelicase ATP-binding 2
HgeneASCC3chr6:101037510chr6:100901720ENST00000522650-1131544_17390732.0DomainHelicase C-terminal 2
HgeneASCC3chr6:101037510chr6:100901720ENST00000522650-1131812_21760732.0DomainNote=SEC63 2
HgeneASCC3chr6:101037510chr6:100901720ENST00000522650-113486_6690732.0DomainHelicase ATP-binding 1
HgeneASCC3chr6:101037510chr6:100901720ENST00000522650-113728_9140732.0DomainHelicase C-terminal 1
HgeneASCC3chr6:101037510chr6:100901720ENST00000522650-113978_12870732.0DomainNote=SEC63 1
HgeneASCC3chr6:101037510chr6:100901720ENST00000369143-141453_14560112.0MotifNote=DEIH box
HgeneASCC3chr6:101037510chr6:100901720ENST00000369143-14611_6140112.0MotifNote=DEVH box
HgeneASCC3chr6:101037510chr6:100901720ENST00000522650-1131453_14560732.0MotifNote=DEIH box
HgeneASCC3chr6:101037510chr6:100901720ENST00000522650-113611_6140732.0MotifNote=DEVH box
HgeneASCC3chr6:101037510chr6:100901720ENST00000369143-141349_13560112.0Nucleotide bindingATP
HgeneASCC3chr6:101037510chr6:100901720ENST00000369143-14499_5060112.0Nucleotide bindingATP
HgeneASCC3chr6:101037510chr6:100901720ENST00000522650-1131349_13560732.0Nucleotide bindingATP
HgeneASCC3chr6:101037510chr6:100901720ENST00000522650-113499_5060732.0Nucleotide bindingATP
TgeneSIM1chr6:101037510chr6:100901720ENST000002629010111_5358767.0DomainbHLH
TgeneSIM1chr6:101037510chr6:100901720ENST000003692081121_5358767.0DomainbHLH


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Fusion Gene Sequence for ASCC3-SIM1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>7065_7065_1_ASCC3-SIM1_ASCC3_chr6_101037510_ENST00000369162_SIM1_chr6_100901720_ENST00000262901_length(transcript)=9510nt_BP=5895nt
AGCGGGGCGGTGACGTGTAGGCCGGCGCCAGCTCCACTCTGTCCCTCCTCGCCGGGTCTGTGCGTCTTTGCGTCTGTCTGTCTGACTGAT
GGTCCTCACACGCGGTTCCCTGTGACTGGGCGCGACCCCGGCAAGCGCGGCTTGGAGGGCGGACGGGGCGCGGCGATACAGCTGCCCGCT
CGCATCTTTGGCCCTGCGCTCAGCTCCTCACCCGGCGTGGGAAGTTAAAGTAAAACCGAAAGGGAAGAAGGCGCGGTGGCAGGAGCTGAC
AGAGTGATGGGAAACGCGTGAGCCAGGCCGAGAGTTTCAGGTTTCTTGCTGTATGGATCACTGATTGAATAATAGATGGCTTTACCTCGT
CTCACAGGAGCCTTGCGTTCCTTTTCAAATGTCACCAAGCAAGATAATTATAATGAAGAAGTGGCTGACTTAAAGATAAAGCGATCTAAA
CTTCATGAACAAGTTTTAGATTTGGGCCTGACATGGAAGAAGATAATAAAATTTTTGAATGAAAAACTGGAGAAGAGTAAAATGCAAAGT
ATAAATGAAGACTTAAAAGATATATTACATGCTGCAAAGCAGATAGTTGGAACTGATAATGGGAGAGAAGCAATTGAAAGTGGGGCTGCA
TTTCTCTTCATGACATTTCACTTGAAGGACTCTGTTGGTCACAAGGAAACAAAGGCTATCAAACAGATGTTTGGCCCCTTTCCTTCATCA
TCTGCCACTGCAGCTTGTAATGCTACTAATCGAATTATTTCTCATTTTAGTCAAGATGATCTTACTGCTCTTGTGCAGATGACAGAAAAA
GAACATGGCGATAGGGTTTTTTTTGGTAAAAATTTAGCATTTTCATTTGACATGCATGATTTGGACCACTTTGACGAACTGCCAATAAAT
GGTGAAACTCAGAAAACTATAAGCCTAGATTATAAGAAGTTTCTGAATGAACATCTCCAGGAGGCTTGCACCCCAGAACTCAAGCCTGTG
GAAAAAACAAATGGCTCCTTTTTGTGGTGTGAAGTTGAAAAGTACCTAAATTCAACTTTGAAGGAAATGACTGAAGTGCCAAGAGTAGAA
GATCTTTGCTGTACTTTATATGATATGCTTGCTTCTATTAAAAGTGGTGATGAACTTCAGGATGAGCTATTTGAACTGCTGGGACCTGAA
GGACTTGAACTTATTGAGAAACTCCTCCAGAACAGAATTACAATTGTGGATAGATTTCTTAATTCTTCAAATGATCATAGGTTTCAGGCT
CTTCAAGACAATTGTAAAAAAATTTTAGGAGAAAATGCTAAACCCAATTATGGTTGTCAAGTCACTATTCAGTCTGAACAAGAAAAGCAG
TTAATGAAACAATATCGACGTGAAGAAAAAAGAATTGCCAGACGAGAAAAAAAGGCTGGAGAAGATTTAGAAGTTTCAGAAGGACTTATG
TGCTTTGATCCTAAGGAATTGCGGATACAAAGAGAACAGGCACTTCTGAATGCTAGAAGTGTTCCAATTCTGAGCAGGCAGAGAGATGCA
GACGTTGAAAAAATACATTATCCCCATGTGTATGATTCCCAGGCTGAAGCCATGAAAACATCAGCATTTATTGCTGGTGCAAAGATGATT
TTGCCAGAAGGAATCCAAAGAGAGAATAACAAGCTTTATGAAGAAGTAAGGATTCCCTACAGCGAACCAATGCCACTCAGCTTTGAGGAA
AAGCCAGTTTATATCCAAGACTTAGATGAGATCGGACAGCTGGCTTTTAAAGGAATGAAGAGACTCAATAGAATCCAGTCAATAGTGTTT
GAGACTGCCTACAACACCAATGAGAACATGCTGATTTGTGCCCCTACAGGAGCTGGAAAAACCAACATTGCAATGCTGACAGTCTTGCAT
GAAATTCGCCAACATTTTCAACAAGGTGTTATCAAAAAGAATGAATTTAAGATTGTATATGTTGCTCCAATGAAAGCCTTGGCAGCTGAA
ATGACAGATTACTTCAGCAGACGTCTAGAGCCACTAGGCATCATTGTGAAAGAATTGACTGGTGACATGCAGTTGTCCAAAAGTGAAATT
TTACGAACTCAGATGCTTGTGACCACACCAGAAAAATGGGATGTAGTGACAAGAAAGAGTGTTGGGGATGTAGCTCTTTCCCAGATTGTA
AGGCTCCTTATTCTTGATGAAGTTCATTTGCTGCATGAAGATAGAGGACCAGTATTAGAAAGCATAGTTGCCCGTACTTTACGGCAGGTG
GAATCCACACAGAGTATGATAAGGATTCTCGGACTGTCTGCAACTTTACCTAACTACCTCGATGTTGCCACATTTTTACATGTTAATCCA
TACATTGGACTTTTCTTCTTTGATGGCCGTTTTCGACCAGTACCTCTTGGACAGACATTTTTGGGGATTAAATGTGCAAATAAGATGCAG
CAGTTGAATAACATGGATGAAGTATGTTATGAAAATGTTTTGAAGCAAGTAAAGGCTGGACACCAGGTGATGGTGTTTGTACATGCTCGA
AATGCCACTGTAAGAACAGCTATGTCTCTAATAGAAAGAGCAAAAAATTGTGGCCATATTCCCTTCTTTTTTCCTACCCAAGGACATGAC
TATGTACTTGCAGAAAAACAGGTACAAAGGTCGAGAAATAAGCAAGTACGAGAATTATTCCCAGATGGTTTTAGTATTCATCATGCAGGA
ATGCTTCGGCAGGACAGAAATTTAGTTGAAAACTTGTTTTCTAATGGGCATATCAAAGTCCTAGTGTGTACAGCTACGTTAGCCTGGGGT
GTCAATCTTCCCGCCCATGCTGTTATTATTAAGGGAACACAAATATATGCTGCAAAAAGAGGCTCCTTTGTTGACCTTGGAATTTTAGAT
GTCATGCAGATATTTGGTCGAGCTGGACGACCACAATTTGACAAATTTGGGGAAGGAATAATTATAACAACGCATGATAAACTCAGCCAT
TACCTCACTTTGCTCACTCAACGAAACCCAATTGAGAGTCAGTTTCTGGAAAGCCTTGCAGATAACCTAAATGCAGAGATTGCTCTGGGA
ACAGTTACTAATGTGGAAGAAGCAGTGAAGTGGATAAGTTACACTTATCTTTATGTACGGATGAGAGCAAATCCATTAGCATATGGCATC
AGTCACAAGGCTTATCAGATTGACCCAACATTAAGAAAGCATCGAGAACAGTTGGTCATTGAAGTTGGACGAAAACTAGACAAAGCTCAG
ATGATTCGTTTTGAGGAGCGAACTGGATATTTTTCCTCAACTGATTTGGGTAGAACTGCCAGCCATTACTATATTAAATACAACACCATT
GAGACCTTTAATGAACTCTTTGATGCTCACAAAACAGAAGGTGATATCTTTGCCATAGTCTCCAAAGCTGAAGAATTTGATCAAATTAAG
GTCAGAGAAGAGGAAATAGAGGAGTTAGATACCTTATTAAGCAATTTTTGTGAACTCTCCACTCCTGGAGGTGTAGAGAATAGTTATGGG
AAAATAAACATCTTACTTCAAACTTATATCAGCCGAGGAGAAATGGACAGTTTCTCCCTTATATCAGATTCTGCATATGTTGCACAGAAT
GCAGCTAGAATTGTCCGTGCTCTTTTTGAAATTGCTCTGAGGAAACGTTGGCCTACCATGACCTACAGGCTCCTGAATCTTAGTAAAGTC
ATTGACAAGAGGCTTTGGGGTTGGGCTAGCCCTTTGAGACAATTTTCAATCCTACCACCACACATCCTAACAAGATTAGAAGAAAAAAAG
CTTACTGTGGATAAGCTGAAAGACATGAGGAAAGATGAAATAGGTCACATTTTACATCATGTGAATATTGGACTGAAGGTCAAACAATGT
GTTCATCAGATTCCTTCTGTTATGATGGAAGCATCCATTCAGCCTATCACAAGGACTGTCCTCCGAGTGACACTCAGCATCTATGCTGAT
TTCACTTGGAATGATCAGGTACATGGGACAGTAGGAGAACCTTGGTGGATTTGGGTAGAAGATCCTACAAATGATCATATTTATCATTCA
GAGTATTTTCTAGCTCTAAAAAAACAAGTCATTAGTAAAGAAGCCCAACTACTGGTATTTACAATCCCTATTTTTGAGCCTTTGCCTTCC
CAATACTACATCCGAGCAGTGTCTGATAGATGGTTGGGTGCTGAGGCAGTATGTATTATCAACTTTCAACATCTAATTCTACCAGAGAGA
CATCCTCCTCATACAGAATTACTGGATCTTCAGCCTTTACCAATCACAGCTTTGGGATGTAAAGCATATGAAGCCCTGTACAACTTCAGC
CACTTTAACCCTGTACAGACACAAATATTTCATACATTGTATCACACGGATTGTAATGTCCTACTTGGAGCACCTACTGGATCGGGAAAG
ACTGTTGCAGCTGAATTAGCCATTTTCAGAGTCTTCAACAAATACCCTACTTCAAAGGCGGTATATATTGCACCCCTAAAAGCCCTAGTA
CGTGAAAGAATGGATGATTGGAAAGTTAGAATAGAAGAAAAACTTGGTAAAAAAGTTATTGAACTAACAGGGGATGTGACTCCTGATATG
AAATCCATTGCCAAGGCTGACCTTATCGTCACTACGCCAGAGAAGTGGGATGGAGTCAGCAGAAGCTGGCAAAATAGGAACTATGTTCAG
CAAGTCACTATTCTCATCATAGATGAGATCCATCTGCTTGGGGAGGAAAGAGGCCCTGTTCTAGAGGTCATTGTATCTCGAACAAATTTT
ATCTCATCACACACAGAAAAGCCTGTTAGAATAGTTGGACTATCTACTGCATTAGCTAATGCCAGAGACCTTGCTGATTGGCTCAATATT
AAGCAGATGGGCTTGTTTAACTTCCGACCATCAGTACGCCCAGTTCCACTGGAAGTTCACATTCAAGGCTTTCCAGGTCAACATTACTGT
CCTCGTATGGCTAGTATGAACAAGCCTGCATTTCAGGCAATTAGAAGCCATTCTCCAGCCAAACCTGTTTTGATATTTGTCTCATCAAGA
CGTCAAACTCGTCTTACTGCTTTGGAATTGATCGCCTTCCTGGCTACTGAAGAAGATCCAAAGCAGTGGTTAAACATGGATGAAAGAGAG
ATGGAGAACATCATTGCAACAGTAAGAGATTCCAACCTCAAGCTGACCCTTGCTTTCGGGATAGGAATGCATCATGCTGGACTACATGAG
AGGGACCGAAAAACAGTAGAGGAACTATTTGTAAACTGTAAAGTTCAGGTTCTTATTGCTACAAGCACATTAGCCTGGGGTGTAAACTTT
CCAGCTCATTTAGTAATTATTAAGGGAACAGAATACTATGATGGAAAAACAAGACGTTATGTGGATTTTCCCATTACAGATGTCCTCCAG
ATGATGGGGCGTGCTGGGAGGCCGCAGTTCGATGACCAAGGCAAAGCTGTAATTCTAGTTCATGACATAAAGAAAGACTTTTATAAAAAA
TTTCTTTATGAACCTTTCCCAGTAGAATCAAGTTTATTAGGAGTGCTCTCTGACCACTTAAATGCAGAGATTGCTGGTGGTACAATTACA
TCTAAGCAAGATGCATTGGATTATATCACCTGGACTTACTTTTTCCGACGTCTTATCATGAATCCCAGCTATTACAATTTGGGTGATGTG
AGCCATGATTCTGTGAACAAGTTTCTGTCCCATCTGATTGAGAAGTCCCTGATTGAATTGGAACTTTCCTACTGTATTGAAATTGGAGAG
GATAATCGCAGCATTGAACCTCTAACTTATGGCCGAATTGCCTCCTATTACTATTTGAAGCATCAAACAGTTAAAATGTTCAAGGACCGC
TTGAAGCCTGAATGCAGTACTGAAGAACTGCTTTCAATTCTAAGTGGCTCGGCGAGGCGTGGGGCCACTCAAGTCGGACCAGCCCCCTGG
ACAACGTTGGCCGAGAACTGGGCTCCCATCTGCTCCAGACCCTGGATGGCTTCATCTTCGTGGTAGCCCCAGATGGGAAGATCATGTACA
TCTCAGAGACAGCCTCAGTCCACTTGGGTCTTTCTCAGGTAGAGCTGACCGGAAACAGCATTTATGAATACATTCACCCGGCAGACCACG
ACGAGATGACGGCGGTGCTCACCGCCCATCAACCCTACCACTCTCACTTCGTGCAGGAGTATGAGATCGAGCGCTCCTTCTTCCTGAGGA
TGAAGTGCGTCTTGGCCAAGCGTAACGCCGGCCTCACCTGTGGCGGCTACAAGGTCATCCACTGCAGCGGCTACTTGAAGATCCGCCAGT
ACAGCCTGGACATGTCCCCCTTCGACGGCTGCTACCAAAACGTGGGCCTGGTGGCCGTGGGCCACTCGCTGCCTCCCAGCGCCGTCACGG
AGATCAAGCTACACAGCAATATGTTTATGTTCCGCGCCAGCCTGGACATGAAGCTCATCTTTCTGGACTCCAGGGTGGCGGAGCTGACGG
GGTACGAACCTCAGGACCTGATTGAGAAGACTCTGTACCACCATGTGCACGGCTGCGACACCTTCCACCTGCGCTGCGCGCACCATTTGC
TGCTGGTGAAGGGACAGGTGACCACCAAGTACTACAGGTTCCTGGCGAAACACGGCGGCTGGGTATGGGTGCAGAGCTACGCGACCATCG
TGCACAACAGTCGCTCCTCCAGGCCACACTGTATCGTCAGCGTCAACTATGTCCTCACAGACACAGAATACAAAGGGCTGCAGCTCTCCC
TGGATCAGATCTCAGCCTCCAAACCAGCCTTCTCCTATACCAGCAGCTCCACCCCCACCATGACTGACAACAGAAAGGGGGCCAAATCCC
GGCTCTCCAGCTCAAAGTCAAAATCCAGGACTTCCCCATACCCTCAGTATTCGGGATTTCACACAGAAAGATCGGAATCTGATCATGACA
GCCAGTGGGGCGGAAGTCCCTTGACCGACACGGCCTCTCCGCAGCTTCTGGACCCCGCCGATAGGCCTGGCTCCCAGCACGACGCATCGT
GCGCCTACAGACAGTTTTCGGACCGCAGCTCTCTCTGCTATGGCTTTGCGCTTGACCACTCGAGGCTGGTGGAAGAGAGGCATTTCCATA
CCCAGGCCTGTGAAGGAGGCCGATGTGAGGCAGGCAGGTACTTCCTGGGAACGCCGCAGGCCGGGAGGGAGCCCTGGTGGGGCTCTCGCG
CAGCCTTGCCCCTGACAAAGGCCTCCCCAGAAAGCAGAGAAGCCTATGAAAACAGCATGCCTCACATCGCTTCAGTCCACAGGATCCATG
GGCGAGGTCATTGGGATGAAGATAGTGTGGTCAGTTCTCCAGACCCTGGGTCGGCCAGTGAATCAGGTGACCGATATCGTACTGAGCAGT
ATCAAAGTAGCCCACATGAACCCAGCAAAATTGAAACTCTTATAAGAGCCACTCAGCAAATGATTAAAGAAGAAGAGAACAGATTACAGC
TAAGGAAAGCCCCCTCAGACCAACTGGCTTCCATTAATGGGGCTGGGAAAAAACACTCCCTGTGTTTTGCAAACTACCAACAGCCCCCAC
CAACAGGTGAAGTCTGCCATGGCTCTGCTCTTGCCAACACTTCACCATGTGACCATATCCAGCAGAGAGAGGGAAAAATGTTGAGCCCCC
ATGAAAATGACTATGACAACAGTCCCACCGCACTATCTCGGATAAGTAGTCCCAATTCGGATCGCATTTCAAAATCCAGTTTGATCCTAG
CTAAAGACTATCTGCATTCGGATATATCTCCTCATCAGACAGCAGGAGACCACCCTACTGTCTCTCCAAACTGCTTTGGCTCTCACCGGC
AGTATTTTGACAAGCATGCTTACACATTAACTGGATATGCCCTGGAGCACTTATATGACAGCGAAACCATTAGAAACTATTCCTTGGGCT
GTAATGGCTCACACTTTGATGTAACTTCCCATCTGAGGATGCAACCAGACCCAGCACAAGGACACAAGGGAACATCTGTTATAATAACCA
ACGGAAGCTGATGTTTTGCTGAAATATTTTGTTCTTTAAGGATCTCTGAAACATATTTATAGTTTAATACCCCATTACCAGCATTTACTA
TGCCACAGATTGTTAGAGAGTATAACTTAAGTTACTGGGTATTTGATACGTGTTCCTATAAAATCAAAGAAAACATAGCACTAGCATTCA
GGGTTATACACAGAAAAGGGAGCTAAATTGAATACACAAATTTCCCCTCTAATTATATGGGAACCAGAATAGATAAATTTTGACTTGAAA
AATATTCATGTAGATCAAGTGTGCATATATACTACATGAGAGGACTGATGAATGACAACATTGCATTGTGACTATCCAGTGATCCTCAAA
CACACAAACTATTACTTACAAACTGCGGTATACATTTTACATATGGAAATATAGGCTATGTAATGTAAATACATCAAAAATGGGTAATTT
TCTTTGACTCTGTCACACTAAACTTCTTAACGAAATTTCCATTCCCAAAATAACTGAGAAAGAGAGAGATACATCTTATAAACTGACTTC
TTTGTGGTTTCAAATCAGCCAGCTCATTTGGTTCAGGCATAAATTAGAGAAATGGTTCTGGATATGGTGCAAAAATGAGTTTTCACCTGG
TATCCATTATAAACAATCAGGAAGAGGTAATTTTTCACCTTGCTTTTCAGTTAGACAAGGACCAGGATTGCACTGACATGGCGCTGAGGG
TTTTTCTAAGTAAGAACACTGAGATATTGGGACACACATCAAAAACCTGGAGTGCTCAATTGGAAGTAGTTCTATGAATATGGAAAGGCC
AGAGGCAGAGTGAAATAAAATGCTATCTCAAAGTTTAACACAATTTAAGGGCTCAGCATAAGTAAACAACATATTTGGGGTTTGCTTGTA
AAACCAACTAAATAAAAAATTCAAACCAATTCACCCAGAAAAAAGACCAATAGGTGCAAAAATAAAAGGAAAACCAGTGAAGTGCCACAT
GACAGCAGTGTTAAGTGTTTGAAAACGTTTCAAAGCACATATGTGCCAATGTGACAACATGTGGAAAGCCTCAGGAGAGAGTCTAAGATA
AAAGCTTAGGCTGATAGACAAGTAGTTAAGAGCTAAGAGCAGTACTCTGAAGGAATAGGCAAAATGTTTATTTTCCTTATTGTTTGTAAA
CAACAAACTTGGTCTTACATCTGTGTGGTATAGTAGAAAGGCCAGCTGACTAGATCTCTGGATTCTAATTTTGGCCCTACCTGTAACTTA
ATTTTGTGACCACAGTTGTACCATTCACCGTGCCTGGGCTCTAGTTTCCTGGTTTGTAAGGCAGCCCCAGCGTTCATGTTCTGTGATAGA
GCAGAACTGAACTTATTACCTAATTAACTCTCTGCTATGAGTTGTCAAGACTGATCATTCTGTTTTTTCTGTACACAGAAGTTTAGATGC

>7065_7065_1_ASCC3-SIM1_ASCC3_chr6_101037510_ENST00000369162_SIM1_chr6_100901720_ENST00000262901_length(amino acids)=1886AA_BP=0
MALPRLTGALRSFSNVTKQDNYNEEVADLKIKRSKLHEQVLDLGLTWKKIIKFLNEKLEKSKMQSINEDLKDILHAAKQIVGTDNGREAI
ESGAAFLFMTFHLKDSVGHKETKAIKQMFGPFPSSSATAACNATNRIISHFSQDDLTALVQMTEKEHGDRVFFGKNLAFSFDMHDLDHFD
ELPINGETQKTISLDYKKFLNEHLQEACTPELKPVEKTNGSFLWCEVEKYLNSTLKEMTEVPRVEDLCCTLYDMLASIKSGDELQDELFE
LLGPEGLELIEKLLQNRITIVDRFLNSSNDHRFQALQDNCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDLEV
SEGLMCFDPKELRIQREQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKTSAFIAGAKMILPEGIQRENNKLYEEVRIPYSEPMP
LSFEEKPVYIQDLDEIGQLAFKGMKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMK
ALAAEMTDYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEVHLLHEDRGPVLESIVAR
TLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMV
FVHARNATVRTAMSLIERAKNCGHIPFFFPTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTA
TLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNA
EIALGTVTNVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIRFEERTGYFSSTDLGRTASHYYI
KYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEIEELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSA
YVAQNAARIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTVDKLKDMRKDEIGHILHHVNIGL
KVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIF
EPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFNPVQTQIFHTLYHTDCNVLLGAP
TGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQN
RNYVQQVTILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRPVPLEVHIQGFP
GQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHH
AGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKK
DFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYC

--------------------------------------------------------------
>7065_7065_2_ASCC3-SIM1_ASCC3_chr6_101037510_ENST00000369162_SIM1_chr6_100901720_ENST00000369208_length(transcript)=13367nt_BP=5895nt
AGCGGGGCGGTGACGTGTAGGCCGGCGCCAGCTCCACTCTGTCCCTCCTCGCCGGGTCTGTGCGTCTTTGCGTCTGTCTGTCTGACTGAT
GGTCCTCACACGCGGTTCCCTGTGACTGGGCGCGACCCCGGCAAGCGCGGCTTGGAGGGCGGACGGGGCGCGGCGATACAGCTGCCCGCT
CGCATCTTTGGCCCTGCGCTCAGCTCCTCACCCGGCGTGGGAAGTTAAAGTAAAACCGAAAGGGAAGAAGGCGCGGTGGCAGGAGCTGAC
AGAGTGATGGGAAACGCGTGAGCCAGGCCGAGAGTTTCAGGTTTCTTGCTGTATGGATCACTGATTGAATAATAGATGGCTTTACCTCGT
CTCACAGGAGCCTTGCGTTCCTTTTCAAATGTCACCAAGCAAGATAATTATAATGAAGAAGTGGCTGACTTAAAGATAAAGCGATCTAAA
CTTCATGAACAAGTTTTAGATTTGGGCCTGACATGGAAGAAGATAATAAAATTTTTGAATGAAAAACTGGAGAAGAGTAAAATGCAAAGT
ATAAATGAAGACTTAAAAGATATATTACATGCTGCAAAGCAGATAGTTGGAACTGATAATGGGAGAGAAGCAATTGAAAGTGGGGCTGCA
TTTCTCTTCATGACATTTCACTTGAAGGACTCTGTTGGTCACAAGGAAACAAAGGCTATCAAACAGATGTTTGGCCCCTTTCCTTCATCA
TCTGCCACTGCAGCTTGTAATGCTACTAATCGAATTATTTCTCATTTTAGTCAAGATGATCTTACTGCTCTTGTGCAGATGACAGAAAAA
GAACATGGCGATAGGGTTTTTTTTGGTAAAAATTTAGCATTTTCATTTGACATGCATGATTTGGACCACTTTGACGAACTGCCAATAAAT
GGTGAAACTCAGAAAACTATAAGCCTAGATTATAAGAAGTTTCTGAATGAACATCTCCAGGAGGCTTGCACCCCAGAACTCAAGCCTGTG
GAAAAAACAAATGGCTCCTTTTTGTGGTGTGAAGTTGAAAAGTACCTAAATTCAACTTTGAAGGAAATGACTGAAGTGCCAAGAGTAGAA
GATCTTTGCTGTACTTTATATGATATGCTTGCTTCTATTAAAAGTGGTGATGAACTTCAGGATGAGCTATTTGAACTGCTGGGACCTGAA
GGACTTGAACTTATTGAGAAACTCCTCCAGAACAGAATTACAATTGTGGATAGATTTCTTAATTCTTCAAATGATCATAGGTTTCAGGCT
CTTCAAGACAATTGTAAAAAAATTTTAGGAGAAAATGCTAAACCCAATTATGGTTGTCAAGTCACTATTCAGTCTGAACAAGAAAAGCAG
TTAATGAAACAATATCGACGTGAAGAAAAAAGAATTGCCAGACGAGAAAAAAAGGCTGGAGAAGATTTAGAAGTTTCAGAAGGACTTATG
TGCTTTGATCCTAAGGAATTGCGGATACAAAGAGAACAGGCACTTCTGAATGCTAGAAGTGTTCCAATTCTGAGCAGGCAGAGAGATGCA
GACGTTGAAAAAATACATTATCCCCATGTGTATGATTCCCAGGCTGAAGCCATGAAAACATCAGCATTTATTGCTGGTGCAAAGATGATT
TTGCCAGAAGGAATCCAAAGAGAGAATAACAAGCTTTATGAAGAAGTAAGGATTCCCTACAGCGAACCAATGCCACTCAGCTTTGAGGAA
AAGCCAGTTTATATCCAAGACTTAGATGAGATCGGACAGCTGGCTTTTAAAGGAATGAAGAGACTCAATAGAATCCAGTCAATAGTGTTT
GAGACTGCCTACAACACCAATGAGAACATGCTGATTTGTGCCCCTACAGGAGCTGGAAAAACCAACATTGCAATGCTGACAGTCTTGCAT
GAAATTCGCCAACATTTTCAACAAGGTGTTATCAAAAAGAATGAATTTAAGATTGTATATGTTGCTCCAATGAAAGCCTTGGCAGCTGAA
ATGACAGATTACTTCAGCAGACGTCTAGAGCCACTAGGCATCATTGTGAAAGAATTGACTGGTGACATGCAGTTGTCCAAAAGTGAAATT
TTACGAACTCAGATGCTTGTGACCACACCAGAAAAATGGGATGTAGTGACAAGAAAGAGTGTTGGGGATGTAGCTCTTTCCCAGATTGTA
AGGCTCCTTATTCTTGATGAAGTTCATTTGCTGCATGAAGATAGAGGACCAGTATTAGAAAGCATAGTTGCCCGTACTTTACGGCAGGTG
GAATCCACACAGAGTATGATAAGGATTCTCGGACTGTCTGCAACTTTACCTAACTACCTCGATGTTGCCACATTTTTACATGTTAATCCA
TACATTGGACTTTTCTTCTTTGATGGCCGTTTTCGACCAGTACCTCTTGGACAGACATTTTTGGGGATTAAATGTGCAAATAAGATGCAG
CAGTTGAATAACATGGATGAAGTATGTTATGAAAATGTTTTGAAGCAAGTAAAGGCTGGACACCAGGTGATGGTGTTTGTACATGCTCGA
AATGCCACTGTAAGAACAGCTATGTCTCTAATAGAAAGAGCAAAAAATTGTGGCCATATTCCCTTCTTTTTTCCTACCCAAGGACATGAC
TATGTACTTGCAGAAAAACAGGTACAAAGGTCGAGAAATAAGCAAGTACGAGAATTATTCCCAGATGGTTTTAGTATTCATCATGCAGGA
ATGCTTCGGCAGGACAGAAATTTAGTTGAAAACTTGTTTTCTAATGGGCATATCAAAGTCCTAGTGTGTACAGCTACGTTAGCCTGGGGT
GTCAATCTTCCCGCCCATGCTGTTATTATTAAGGGAACACAAATATATGCTGCAAAAAGAGGCTCCTTTGTTGACCTTGGAATTTTAGAT
GTCATGCAGATATTTGGTCGAGCTGGACGACCACAATTTGACAAATTTGGGGAAGGAATAATTATAACAACGCATGATAAACTCAGCCAT
TACCTCACTTTGCTCACTCAACGAAACCCAATTGAGAGTCAGTTTCTGGAAAGCCTTGCAGATAACCTAAATGCAGAGATTGCTCTGGGA
ACAGTTACTAATGTGGAAGAAGCAGTGAAGTGGATAAGTTACACTTATCTTTATGTACGGATGAGAGCAAATCCATTAGCATATGGCATC
AGTCACAAGGCTTATCAGATTGACCCAACATTAAGAAAGCATCGAGAACAGTTGGTCATTGAAGTTGGACGAAAACTAGACAAAGCTCAG
ATGATTCGTTTTGAGGAGCGAACTGGATATTTTTCCTCAACTGATTTGGGTAGAACTGCCAGCCATTACTATATTAAATACAACACCATT
GAGACCTTTAATGAACTCTTTGATGCTCACAAAACAGAAGGTGATATCTTTGCCATAGTCTCCAAAGCTGAAGAATTTGATCAAATTAAG
GTCAGAGAAGAGGAAATAGAGGAGTTAGATACCTTATTAAGCAATTTTTGTGAACTCTCCACTCCTGGAGGTGTAGAGAATAGTTATGGG
AAAATAAACATCTTACTTCAAACTTATATCAGCCGAGGAGAAATGGACAGTTTCTCCCTTATATCAGATTCTGCATATGTTGCACAGAAT
GCAGCTAGAATTGTCCGTGCTCTTTTTGAAATTGCTCTGAGGAAACGTTGGCCTACCATGACCTACAGGCTCCTGAATCTTAGTAAAGTC
ATTGACAAGAGGCTTTGGGGTTGGGCTAGCCCTTTGAGACAATTTTCAATCCTACCACCACACATCCTAACAAGATTAGAAGAAAAAAAG
CTTACTGTGGATAAGCTGAAAGACATGAGGAAAGATGAAATAGGTCACATTTTACATCATGTGAATATTGGACTGAAGGTCAAACAATGT
GTTCATCAGATTCCTTCTGTTATGATGGAAGCATCCATTCAGCCTATCACAAGGACTGTCCTCCGAGTGACACTCAGCATCTATGCTGAT
TTCACTTGGAATGATCAGGTACATGGGACAGTAGGAGAACCTTGGTGGATTTGGGTAGAAGATCCTACAAATGATCATATTTATCATTCA
GAGTATTTTCTAGCTCTAAAAAAACAAGTCATTAGTAAAGAAGCCCAACTACTGGTATTTACAATCCCTATTTTTGAGCCTTTGCCTTCC
CAATACTACATCCGAGCAGTGTCTGATAGATGGTTGGGTGCTGAGGCAGTATGTATTATCAACTTTCAACATCTAATTCTACCAGAGAGA
CATCCTCCTCATACAGAATTACTGGATCTTCAGCCTTTACCAATCACAGCTTTGGGATGTAAAGCATATGAAGCCCTGTACAACTTCAGC
CACTTTAACCCTGTACAGACACAAATATTTCATACATTGTATCACACGGATTGTAATGTCCTACTTGGAGCACCTACTGGATCGGGAAAG
ACTGTTGCAGCTGAATTAGCCATTTTCAGAGTCTTCAACAAATACCCTACTTCAAAGGCGGTATATATTGCACCCCTAAAAGCCCTAGTA
CGTGAAAGAATGGATGATTGGAAAGTTAGAATAGAAGAAAAACTTGGTAAAAAAGTTATTGAACTAACAGGGGATGTGACTCCTGATATG
AAATCCATTGCCAAGGCTGACCTTATCGTCACTACGCCAGAGAAGTGGGATGGAGTCAGCAGAAGCTGGCAAAATAGGAACTATGTTCAG
CAAGTCACTATTCTCATCATAGATGAGATCCATCTGCTTGGGGAGGAAAGAGGCCCTGTTCTAGAGGTCATTGTATCTCGAACAAATTTT
ATCTCATCACACACAGAAAAGCCTGTTAGAATAGTTGGACTATCTACTGCATTAGCTAATGCCAGAGACCTTGCTGATTGGCTCAATATT
AAGCAGATGGGCTTGTTTAACTTCCGACCATCAGTACGCCCAGTTCCACTGGAAGTTCACATTCAAGGCTTTCCAGGTCAACATTACTGT
CCTCGTATGGCTAGTATGAACAAGCCTGCATTTCAGGCAATTAGAAGCCATTCTCCAGCCAAACCTGTTTTGATATTTGTCTCATCAAGA
CGTCAAACTCGTCTTACTGCTTTGGAATTGATCGCCTTCCTGGCTACTGAAGAAGATCCAAAGCAGTGGTTAAACATGGATGAAAGAGAG
ATGGAGAACATCATTGCAACAGTAAGAGATTCCAACCTCAAGCTGACCCTTGCTTTCGGGATAGGAATGCATCATGCTGGACTACATGAG
AGGGACCGAAAAACAGTAGAGGAACTATTTGTAAACTGTAAAGTTCAGGTTCTTATTGCTACAAGCACATTAGCCTGGGGTGTAAACTTT
CCAGCTCATTTAGTAATTATTAAGGGAACAGAATACTATGATGGAAAAACAAGACGTTATGTGGATTTTCCCATTACAGATGTCCTCCAG
ATGATGGGGCGTGCTGGGAGGCCGCAGTTCGATGACCAAGGCAAAGCTGTAATTCTAGTTCATGACATAAAGAAAGACTTTTATAAAAAA
TTTCTTTATGAACCTTTCCCAGTAGAATCAAGTTTATTAGGAGTGCTCTCTGACCACTTAAATGCAGAGATTGCTGGTGGTACAATTACA
TCTAAGCAAGATGCATTGGATTATATCACCTGGACTTACTTTTTCCGACGTCTTATCATGAATCCCAGCTATTACAATTTGGGTGATGTG
AGCCATGATTCTGTGAACAAGTTTCTGTCCCATCTGATTGAGAAGTCCCTGATTGAATTGGAACTTTCCTACTGTATTGAAATTGGAGAG
GATAATCGCAGCATTGAACCTCTAACTTATGGCCGAATTGCCTCCTATTACTATTTGAAGCATCAAACAGTTAAAATGTTCAAGGACCGC
TTGAAGCCTGAATGCAGTACTGAAGAACTGCTTTCAATTCTAAGTGGCTCGGCGAGGCGTGGGGCCACTCAAGTCGGACCAGCCCCCTGG
ACAACGTTGGCCGAGAACTGGGCTCCCATCTGCTCCAGACCCTGGATGGCTTCATCTTCGTGGTAGCCCCAGATGGGAAGATCATGTACA
TCTCAGAGACAGCCTCAGTCCACTTGGGTCTTTCTCAGGTAGAGCTGACCGGAAACAGCATTTATGAATACATTCACCCGGCAGACCACG
ACGAGATGACGGCGGTGCTCACCGCCCATCAACCCTACCACTCTCACTTCGTGCAGGAGTATGAGATCGAGCGCTCCTTCTTCCTGAGGA
TGAAGTGCGTCTTGGCCAAGCGTAACGCCGGCCTCACCTGTGGCGGCTACAAGGTCATCCACTGCAGCGGCTACTTGAAGATCCGCCAGT
ACAGCCTGGACATGTCCCCCTTCGACGGCTGCTACCAAAACGTGGGCCTGGTGGCCGTGGGCCACTCGCTGCCTCCCAGCGCCGTCACGG
AGATCAAGCTACACAGCAATATGTTTATGTTCCGCGCCAGCCTGGACATGAAGCTCATCTTTCTGGACTCCAGGGTGGCGGAGCTGACGG
GGTACGAACCTCAGGACCTGATTGAGAAGACTCTGTACCACCATGTGCACGGCTGCGACACCTTCCACCTGCGCTGCGCGCACCATTTGC
TGCTGGTGAAGGGACAGGTGACCACCAAGTACTACAGGTTCCTGGCGAAACACGGCGGCTGGGTATGGGTGCAGAGCTACGCGACCATCG
TGCACAACAGTCGCTCCTCCAGGCCACACTGTATCGTCAGCGTCAACTATGTCCTCACAGACACAGAATACAAAGGGCTGCAGCTCTCCC
TGGATCAGATCTCAGCCTCCAAACCAGCCTTCTCCTATACCAGCAGCTCCACCCCCACCATGACTGACAACAGAAAGGGGGCCAAATCCC
GGCTCTCCAGCTCAAAGTCAAAATCCAGGACTTCCCCATACCCTCAGTATTCGGGATTTCACACAGAAAGATCGGAATCTGATCATGACA
GCCAGTGGGGCGGAAGTCCCTTGACCGACACGGCCTCTCCGCAGCTTCTGGACCCCGCCGATAGGCCTGGCTCCCAGCACGACGCATCGT
GCGCCTACAGACAGTTTTCGGACCGCAGCTCTCTCTGCTATGGCTTTGCGCTTGACCACTCGAGGCTGGTGGAAGAGAGGCATTTCCATA
CCCAGGCCTGTGAAGGAGGCCGATGTGAGGCAGGCAGGTACTTCCTGGGAACGCCGCAGGCCGGGAGGGAGCCCTGGTGGGGCTCTCGCG
CAGCCTTGCCCCTGACAAAGGCCTCCCCAGAAAGCAGAGAAGCCTATGAAAACAGCATGCCTCACATCGCTTCAGTCCACAGGATCCATG
GGCGAGGTCATTGGGATGAAGATAGTGTGGTCAGTTCTCCAGACCCTGGGTCGGCCAGTGAATCAGGTGACCGATATCGTACTGAGCAGT
ATCAAAGTAGCCCACATGAACCCAGCAAAATTGAAACTCTTATAAGAGCCACTCAGCAAATGATTAAAGAAGAAGAGAACAGATTACAGC
TAAGGAAAGCCCCCTCAGACCAACTGGCTTCCATTAATGGGGCTGGGAAAAAACACTCCCTGTGTTTTGCAAACTACCAACAGCCCCCAC
CAACAGGTGAAGTCTGCCATGGCTCTGCTCTTGCCAACACTTCACCATGTGACCATATCCAGCAGAGAGAGGGAAAAATGTTGAGCCCCC
ATGAAAATGACTATGACAACAGTCCCACCGCACTATCTCGGATAAGTAGTCCCAATTCGGATCGCATTTCAAAATCCAGTTTGATCCTAG
CTAAAGACTATCTGCATTCGGATATATCTCCTCATCAGACAGCAGGAGACCACCCTACTGTCTCTCCAAACTGCTTTGGCTCTCACCGGC
AGTATTTTGACAAGCATGCTTACACATTAACTGGATATGCCCTGGAGCACTTATATGACAGCGAAACCATTAGAAACTATTCCTTGGGCT
GTAATGGCTCACACTTTGATGTAACTTCCCATCTGAGGATGCAACCAGACCCAGCACAAGGACACAAGGGAACATCTGTTATAATAACCA
ACGGAAGCTGATGTTTTGCTGAAATATTTTGTTCTTTAAGGATCTCTGAAACATATTTATAGTTTAATACCCCATTACCAGCATTTACTA
TGCCACAGATTGTTAGAGAGTATAACTTAAGTTACTGGGTATTTGATACGTGTTCCTATAAAATCAAAGAAAACATAGCACTAGCATTCA
GGGTTATACACAGAAAAGGGAGCTAAATTGAATACACAAATTTCCCCTCTAATTATATGGGAACCAGAATAGATAAATTTTGACTTGAAA
AATATTCATGTAGATCAAGTGTGCATATATACTACATGAGAGGACTGATGAATGACAACATTGCATTGTGACTATCCAGTGATCCTCAAA
CACACAAACTATTACTTACAAACTGCGGTATACATTTTACATATGGAAATATAGGCTATGTAATGTAAATACATCAAAAATGGGTAATTT
TCTTTGACTCTGTCACACTAAACTTCTTAACGAAATTTCCATTCCCAAAATAACTGAGAAAGAGAGAGATACATCTTATAAACTGACTTC
TTTGTGGTTTCAAATCAGCCAGCTCATTTGGTTCAGGCATAAATTAGAGAAATGGTTCTGGATATGGTGCAAAAATGAGTTTTCACCTGG
TATCCATTATAAACAATCAGGAAGAGGTAATTTTTCACCTTGCTTTTCAGTTAGACAAGGACCAGGATTGCACTGACATGGCGCTGAGGG
TTTTTCTAAGTAAGAACACTGAGATATTGGGACACACATCAAAAACCTGGAGTGCTCAATTGGAAGTAGTTCTATGAATATGGAAAGGCC
AGAGGCAGAGTGAAATAAAATGCTATCTCAAAGTTTAACACAATTTAAGGGCTCAGCATAAGTAAACAACATATTTGGGGTTTGCTTGTA
AAACCAACTAAATAAAAAATTCAAACCAATTCACCCAGAAAAAAGACCAATAGGTGCAAAAATAAAAGGAAAACCAGTGAAGTGCCACAT
GACAGCAGTGTTAAGTGTTTGAAAACGTTTCAAAGCACATATGTGCCAATGTGACAACATGTGGAAAGCCTCAGGAGAGAGTCTAAGATA
AAAGCTTAGGCTGATAGACAAGTAGTTAAGAGCTAAGAGCAGTACTCTGAAGGAATAGGCAAAATGTTTATTTTCCTTATTGTTTGTAAA
CAACAAACTTGGTCTTACATCTGTGTGGTATAGTAGAAAGGCCAGCTGACTAGATCTCTGGATTCTAATTTTGGCCCTACCTGTAACTTA
ATTTTGTGACCACAGTTGTACCATTCACCGTGCCTGGGCTCTAGTTTCCTGGTTTGTAAGGCAGCCCCAGCGTTCATGTTCTGTGATAGA
GCAGAACTGAACTTATTACCTAATTAACTCTCTGCTATGAGTTGTCAAGACTGATCATTCTGTTTTTTCTGTACACAGAAGTTTAGATGC
TTTGTGACTTAAGCAGGTGTGTGGGCTCCTTTAGGCAGGTTACAGTTAACTTTCTAGATTTAGCCAAAATGTAGTTGGTAGAAATTTATG
ACAGAGAAGAAAAATAGCAAGATTTATTTAATGCTCTATTCTCTAGTAATTAAAGCAAAATGATATAAGTGATTAGAGAGATTTCATAGA
TAATATTTCCTAGGAGTCCCGTGCCCAAAACTCTTGCCATATTTAAGGAAGGGAATGTACTGGCAGAACTTGACTTACAATTTTGGAAAC
AGAACATGAAATTGAATACTCAGGGATTAGTAGTATATTTTCATCATTTAACACAGTTATTTCACAGTCCATAGGTAGGTGACAATCTGA
ACGATAATATGAAAGATGAGTACTGGGTTGTTTGTATATGAAAGGAGAGGCTACATAAAATTAAATAATGTTAACATTTGTGCTGTAAAT
GCAAAAAAGTGCAAGTAAGTGAGAAAGTTAGTGGTTATATATATTTTCAAAAAATTCAAAGTGCAGTTGACCCTTGAATAACATGGGTTT
GAACTGTGCAGATTCACTTATGTGTGGTTTTTTTTCCAATCAAATGCAGATAAAAAACCCAGTATTTGGAGAAATGTGAAACCTGAGTAT
ACAGAGGGCGATGTTTTGTATAAGTGAGCGCCACAGGGCCAACAGGCAGGACTTGAGTATGTGAGAATTTGATTATATGGGGGTAATCCT
GGAACCAACTCCCTGTTTATACCAAGGGGTGACCATACAATAAAAACTAAGTTTTGAATTATACAAAAAAGAGTATTTAGTAATTTTGAG
AAAATTATTTATGAGAAATCCTGGAATACATAAAATGGAGTTTTGATCAATTTGCAACATGAAGTAATGTCTTAAGAATGCTAAAGGTTT
TGTAGAATTCTGTAGATTGATAGATGTTTGGAAGAAAAAATATTTGATGAATATGGTGTATTTTGGAAAGGTAATTTTCACAGATGGGTA
TTTCTGGTGGCTATATATTCTACCAAATGTGCCAGGGACAGAAGCTAAAAGAAATGGAAACTTAAGAACCAGGGAAAATGAACTGATATT
AAAGAAAAGGCTGTCACTAAAGGAATTTCAGTGGAATTTTTATATGGAAGATAGTTAACTGGTGAGAAGAAGAAATTATGAATTTCACAG
ATGAGAGTAATCAGAAGGAATAATGCTCTTTAAAATGACATGACCAATATTTTTAAGAGAATACAGAATTAACTAAATTATATATTGATT
CAAAATTTTGGTAGATTGACCCAGTTTTAAGTACATAACCATTTTAAAATTTACTGAATGTCAATAATTTTATAGTAGCAGTTTTATTAC
ATTACATAAAATGTCATATTGACTCACTATATTGTATAGCTTACATTTTTTGCAATATGGCATGATTATCACAAAATGACCCAAGGTAAG
TTAAGACATTTGATGACAATGTACTTTCTTAATATACATGTGAATGTGTTAAAATGTGTTTATAATCTACATTATTTTGTTCTGTGCAGC
AACATATTTCCTCATAATGAAGATGTCATCTGTGTCTTTTAAAAATAGTATATAAAATAACTACGTTCCCGATAATTTAATCAGTTAAAC
TTAATATGGCTTTAGTTTTAATTCTTGATTTCCATAACTTTGCCAAATGTTGAGAAACATGAAACTTGATTGAAATAGATACAGAAGTAT
GATTTTCATATCACCTTGGGGATACATAAAAATGTGCTCTATCCAATTACTGGTATAATATGTATCAATTCATTAGATGATACATAGCTC
ATGGTTTTGTAGAATTCTGGTTTCTAGTGATAATAAGTATCTTTATTGCCCATTTCACCTGCCATACCTACTTTAAAAATTTGGATGACC
AAAGAAGTGAATGAAGTTTCCCCAATCTTTCTTGGGAAAATTCTGTTTAAATTGTTATTGGGAATATATAGATTTGATGTGTTATTTTGG
GATGTGTAATATTAATGTCACAATCACTACAGGTCAGATATTTAGGTGTGCTTCGGTCCACAAGTCTTTTGTCATATTGTGCTCGCTTAC
CTAAACTGTAATTGCCTGATAAAAGATAATATGACAGTGCTGAGGTGACATTCAAAATGAGACGGGATGCAATAAATGATTGCCTTCAGT
ATTTACACAGAAAAACCACTTGCTCTTTCTTGGTTATATTTCATAGGGCTAGATTGTTTCCATCGGGCACTATTCTTAATTCACTCTATA
CCGTGTTGTCACATGCTGCCTCTGGGCAGAGAATCCCACTTAAAATAAGCTTTAGGGGATCTTCTAGAAAAGGGTAGTGTGCTCCAATTT
TTATTTCTCCTTCTTATGGGGGATGAGGATCAATTATAGTACAAGACCATTTGGAAAATATGCATATATATTTTAAAATGAAATACAAGA
TTTCCGCCCTCAAGATCTAAACCAAGTAAGTTTGATGGATGGCAGCACAGATAAAGAAATCTTCTGAATACACATTTGATTTTTATAGCT
CTCTCTTTCAAGAGTAGGATATTACTAAGATATTCAGTGCAATCTATCAGTCCTAGTAGTATTTAGAAGTGACAGAGTGAATGCTGATAT
TTGGAAAATTGAGCATTTGACCATTTTGGGGTCACTCACCTGGCCTAGTGGAATAGCTTACACTTTAATACAATCAAACACAGTCTTTCT
GATATAAAATGTTTGAATGCCCAGATTTGGTTCCCTAGTTCACTCAAATCATAGATGTTGACATACATCCTGTTTTCATAATGATTTTAA
AAAGAATGTAAATCCTATGGTCCTCCAAATAAATGATTCAACGTTTATGTAAATGTCAAGTTTTTGTGAATAGGGATTTATGTCTAAGAC
AGAAAAATCTACTGAACTAGTTCTTACTGTGGAACTAATTGTGGATAAAACATTCGTTATCATCTAAATTTTAAATGAATGACAACAGTT
ATGGACACATGCAAAAGGTATCAGACATAGAAAATATTGTTGGGGGAAATTTCTGTGTGGTGCTAATTTCTTGTAAGGGTTGTACAGATA
GTGCTTAACTCAAAAAGTGAGAGTGTGGTCATTGCCAAATAGGGGTTTGCTCAGAGTTCCTTCTCTAGGACTGTATGCAGAAAGCATACA
CACACACATACGCACACAGAAAAATATGATTTTTATATCATATTCATGAAAATGTGCCATATCCAATTATAACACACACACACACACACA
CACACACACACACACACACACATAAATAAATAAATGATGGTTCACATAAGAAATCCTAATTGCTAATTTTAAACCAAACATTTGTAGTTT
TGTTTATTGCAACTTTGCTGCATGGGACTTTGCTTTCATAAATCTATATGGGGTTGGGGTTAATTTGCCCTAATTTGCTGACCTGGGACA
CATGTAATCACTGTTAAACTTACACCCGGTAACCCTGATGTGTTTACATTTCAAAAGAAATGAAATTGGCCTGGAAAAAAATTTTGGAAG
TACTGTAAGTCTTTTTTCTTTTTTTTTCCGAAGGGAAATATTTCAAAAAAGGAAACATTATGAGTAGACACTTCAAAAAAGATAAAATAT
TTTACATTTGTTTTTTGACTAATGTGCTATAAAAAGGATTATATTTGTGAGAAAAGATACTGATCGCCAATATTTCAAATACCGTCTTGC
AATGTATAGTTTTTAGTGACATTGTAGTATAAAGCTGTAATTTGAAATTTTACTTTGGAATGTAAAGTAGAAAATATTAGCTATGTCAAT
GATATCTTGCAAAGTGTTCCCATTTATAATTATTTATATTGTAAATAGCTTTCTGAAGTAAATTCGAAGTTAATGTGCATAAAATGTATT

>7065_7065_2_ASCC3-SIM1_ASCC3_chr6_101037510_ENST00000369162_SIM1_chr6_100901720_ENST00000369208_length(amino acids)=1886AA_BP=0
MALPRLTGALRSFSNVTKQDNYNEEVADLKIKRSKLHEQVLDLGLTWKKIIKFLNEKLEKSKMQSINEDLKDILHAAKQIVGTDNGREAI
ESGAAFLFMTFHLKDSVGHKETKAIKQMFGPFPSSSATAACNATNRIISHFSQDDLTALVQMTEKEHGDRVFFGKNLAFSFDMHDLDHFD
ELPINGETQKTISLDYKKFLNEHLQEACTPELKPVEKTNGSFLWCEVEKYLNSTLKEMTEVPRVEDLCCTLYDMLASIKSGDELQDELFE
LLGPEGLELIEKLLQNRITIVDRFLNSSNDHRFQALQDNCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDLEV
SEGLMCFDPKELRIQREQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKTSAFIAGAKMILPEGIQRENNKLYEEVRIPYSEPMP
LSFEEKPVYIQDLDEIGQLAFKGMKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMK
ALAAEMTDYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEVHLLHEDRGPVLESIVAR
TLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMV
FVHARNATVRTAMSLIERAKNCGHIPFFFPTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTA
TLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNA
EIALGTVTNVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIRFEERTGYFSSTDLGRTASHYYI
KYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEIEELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSA
YVAQNAARIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTVDKLKDMRKDEIGHILHHVNIGL
KVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIF
EPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFNPVQTQIFHTLYHTDCNVLLGAP
TGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQN
RNYVQQVTILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRPVPLEVHIQGFP
GQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHH
AGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKK
DFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYC

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Fusion Gene PPI Analysis for ASCC3-SIM1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ASCC3-SIM1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ASCC3-SIM1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneASCC3C0020796Profound Mental Retardation1CTD_human
HgeneASCC3C0025363Mental Retardation, Psychosocial1CTD_human
HgeneASCC3C0917816Mental deficiency1CTD_human
HgeneASCC3C3714756Intellectual Disability1CTD_human
TgeneC0006142Malignant neoplasm of breast1CTD_human
TgeneC0020456Hyperglycemia1CTD_human
TgeneC0028754Obesity1GENOMICS_ENGLAND
TgeneC0678222Breast Carcinoma1CTD_human
TgeneC1257931Mammary Neoplasms, Human1CTD_human
TgeneC1458155Mammary Neoplasms1CTD_human
TgeneC1855520Hyperglycemia, Postprandial1CTD_human
TgeneC4704874Mammary Carcinoma, Human1CTD_human