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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Fusion gene:FGFR1OP-ABCC4 (FusionGDB2 ID:HG11116TG10257)

Fusion Gene Summary for FGFR1OP-ABCC4

check button Fusion gene summary
Fusion gene informationFusion gene name: FGFR1OP-ABCC4
Fusion gene ID: hg11116tg10257
HgeneTgene
Gene symbol

FGFR1OP

ABCC4

Gene ID

11116

10257

Gene namecentrosomal protein 43ATP binding cassette subfamily C member 4
SynonymsFGFR1OP|FOPMOAT-B|MOATB|MRP4
Cytomap('FGFR1OP')('ABCC4')

6q27

13q32.1

Type of geneprotein-codingprotein-coding
DescriptionFGFR1 oncogene partnerfibroblast growth factor receptor 1 oncogene partnermultidrug resistance-associated protein 4MRP/cMOAT-related ABC transporterbA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4)canalicular multispecific organic anion transporter (ABC superfamily)multi-specific organic anion transporter
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000476078, ENST00000349556, 
ENST00000366847, 
Fusion gene scores* DoF score7 X 9 X 5=31520 X 18 X 5=1800
# samples 621
** MAII scorelog2(6/315*10)=-2.39231742277876
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(21/1800*10)=-3.09953567355091
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FGFR1OP [Title/Abstract] AND ABCC4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFGFR1OP(167417299)-ABCC4(95847191), # samples:4
Anticipated loss of major functional domain due to fusion event.FGFR1OP-ABCC4 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
FGFR1OP-ABCC4 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
FGFR1OP-ABCC4 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
FGFR1OP-ABCC4 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFGFR1OP

GO:0006469

negative regulation of protein kinase activity

17888034

HgeneFGFR1OP

GO:0008284

positive regulation of cell proliferation

17888034

HgeneFGFR1OP

GO:0030307

positive regulation of cell growth

17888034

HgeneFGFR1OP

GO:0030335

positive regulation of cell migration

17888034

TgeneABCC4

GO:0032310

prostaglandin secretion

25173977


check buttonFusion gene breakpoints across FGFR1OP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ABCC4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-EB-A431-01AFGFR1OPchr6

167417299

-ABCC4chr13

95847191

-
ChimerDB4SKCMTCGA-EB-A431-01AFGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
ChimerDB4SKCMTCGA-EB-A431FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-


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Fusion Gene ORF analysis for FGFR1OP-ABCC4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000476078ENST00000376887FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
3UTR-3CDSENST00000476078ENST00000412704FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
3UTR-3CDSENST00000476078ENST00000431522FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
3UTR-3CDSENST00000476078ENST00000536256FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
3UTR-3UTRENST00000476078ENST00000538287FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
3UTR-intronENST00000476078ENST00000474158FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
5CDS-3UTRENST00000349556ENST00000538287FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
5CDS-3UTRENST00000366847ENST00000538287FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
5CDS-intronENST00000349556ENST00000474158FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
5CDS-intronENST00000366847ENST00000474158FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
In-frameENST00000349556ENST00000376887FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
In-frameENST00000349556ENST00000412704FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
In-frameENST00000349556ENST00000431522FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
In-frameENST00000349556ENST00000536256FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
In-frameENST00000366847ENST00000376887FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
In-frameENST00000366847ENST00000412704FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
In-frameENST00000366847ENST00000431522FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-
In-frameENST00000366847ENST00000536256FGFR1OPchr6

167417299

+ABCC4chr13

95847191

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000366847FGFR1OPchr6167417299+ENST00000412704ABCC4chr1395847191-49535312133206997
ENST00000366847FGFR1OPchr6167417299+ENST00000376887ABCC4chr1395847191-509253121333471044
ENST00000366847FGFR1OPchr6167417299+ENST00000536256ABCC4chr1395847191-23165312131949578
ENST00000366847FGFR1OPchr6167417299+ENST00000431522ABCC4chr1395847191-23145312131949578
ENST00000349556FGFR1OPchr6167417299+ENST00000412704ABCC4chr1395847191-472730552980991
ENST00000349556FGFR1OPchr6167417299+ENST00000376887ABCC4chr1395847191-4866305531211038
ENST00000349556FGFR1OPchr6167417299+ENST00000536256ABCC4chr1395847191-209030551723572
ENST00000349556FGFR1OPchr6167417299+ENST00000431522ABCC4chr1395847191-208830551723572

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000366847ENST00000412704FGFR1OPchr6167417299+ABCC4chr1395847191-0.0001951990.9998048
ENST00000366847ENST00000376887FGFR1OPchr6167417299+ABCC4chr1395847191-0.0002839650.999716
ENST00000366847ENST00000536256FGFR1OPchr6167417299+ABCC4chr1395847191-0.0009623510.9990376
ENST00000366847ENST00000431522FGFR1OPchr6167417299+ABCC4chr1395847191-0.0009641740.99903584
ENST00000349556ENST00000412704FGFR1OPchr6167417299+ABCC4chr1395847191-0.0001728320.9998272
ENST00000349556ENST00000376887FGFR1OPchr6167417299+ABCC4chr1395847191-0.000229570.99977046
ENST00000349556ENST00000536256FGFR1OPchr6167417299+ABCC4chr1395847191-0.0008742990.99912566
ENST00000349556ENST00000431522FGFR1OPchr6167417299+ABCC4chr1395847191-0.000872060.9991279

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Fusion Genomic Features for FGFR1OP-ABCC4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for FGFR1OP-ABCC4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:167417299/chr13:95847191)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFGFR1OPchr6:167417299chr13:95847191ENST00000349556+41270_102100380.0DomainLisH
HgeneFGFR1OPchr6:167417299chr13:95847191ENST00000366847+41370_102100400.0DomainLisH
TgeneABCC4chr6:167417299chr13:95847191ENST000003768877311041_12743871326.0DomainABC transporter 2
TgeneABCC4chr6:167417299chr13:95847191ENST00000376887731410_6333871326.0DomainABC transporter 1
TgeneABCC4chr6:167417299chr13:95847191ENST00000376887731714_10053871326.0DomainABC transmembrane type-1 2
TgeneABCC4chr6:167417299chr13:95847191ENST000004127047301041_12743871279.0DomainABC transporter 2
TgeneABCC4chr6:167417299chr13:95847191ENST00000412704730410_6333871279.0DomainABC transporter 1
TgeneABCC4chr6:167417299chr13:95847191ENST00000412704730714_10053871279.0DomainABC transmembrane type-1 2
TgeneABCC4chr6:167417299chr13:95847191ENST000004315227211041_1274387860.0DomainABC transporter 2
TgeneABCC4chr6:167417299chr13:95847191ENST00000431522721410_633387860.0DomainABC transporter 1
TgeneABCC4chr6:167417299chr13:95847191ENST00000431522721714_1005387860.0DomainABC transmembrane type-1 2
TgeneABCC4chr6:167417299chr13:95847191ENST000003768877311322_13253871326.0MotifNote=PDZ-binding
TgeneABCC4chr6:167417299chr13:95847191ENST000004127047301322_13253871279.0MotifNote=PDZ-binding
TgeneABCC4chr6:167417299chr13:95847191ENST000004315227211322_1325387860.0MotifNote=PDZ-binding
TgeneABCC4chr6:167417299chr13:95847191ENST000003768877311075_10823871326.0Nucleotide bindingATP 2
TgeneABCC4chr6:167417299chr13:95847191ENST00000376887731445_4523871326.0Nucleotide bindingATP 1
TgeneABCC4chr6:167417299chr13:95847191ENST000004127047301075_10823871279.0Nucleotide bindingATP 2
TgeneABCC4chr6:167417299chr13:95847191ENST00000412704730445_4523871279.0Nucleotide bindingATP 1
TgeneABCC4chr6:167417299chr13:95847191ENST000004315227211075_1082387860.0Nucleotide bindingATP 2
TgeneABCC4chr6:167417299chr13:95847191ENST00000431522721445_452387860.0Nucleotide bindingATP 1
TgeneABCC4chr6:167417299chr13:95847191ENST000003768877311038_10583871326.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000376887731440_4603871326.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000376887731710_7303871326.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000376887731771_7913871326.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000376887731836_8563871326.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000376887731858_8783871326.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000376887731954_9743871326.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000376887731977_9973871326.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST000004127047301038_10583871279.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000412704730440_4603871279.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000412704730710_7303871279.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000412704730771_7913871279.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000412704730836_8563871279.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000412704730858_8783871279.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000412704730954_9743871279.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000412704730977_9973871279.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST000004315227211038_1058387860.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000431522721440_460387860.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000431522721710_730387860.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000431522721771_791387860.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000431522721836_856387860.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000431522721858_878387860.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000431522721954_974387860.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000431522721977_997387860.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneABCC4chr6:167417299chr13:95847191ENST0000037688773192_3773871326.0DomainABC transmembrane type-1 1
TgeneABCC4chr6:167417299chr13:95847191ENST0000041270473092_3773871279.0DomainABC transmembrane type-1 1
TgeneABCC4chr6:167417299chr13:95847191ENST0000043152272192_377387860.0DomainABC transmembrane type-1 1
TgeneABCC4chr6:167417299chr13:95847191ENST00000376887731136_1563871326.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000376887731207_2273871326.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000376887731228_2483871326.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000376887731328_3483871326.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000376887731351_3713871326.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST0000037688773193_1133871326.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000412704730136_1563871279.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000412704730207_2273871279.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000412704730228_2483871279.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000412704730328_3483871279.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000412704730351_3713871279.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST0000041270473093_1133871279.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000431522721136_156387860.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000431522721207_227387860.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000431522721228_248387860.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000431522721328_348387860.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST00000431522721351_371387860.0TransmembraneHelical
TgeneABCC4chr6:167417299chr13:95847191ENST0000043152272193_113387860.0TransmembraneHelical


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Fusion Gene Sequence for FGFR1OP-ABCC4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>30254_30254_1_FGFR1OP-ABCC4_FGFR1OP_chr6_167417299_ENST00000349556_ABCC4_chr13_95847191_ENST00000376887_length(transcript)=4866nt_BP=305nt
GCAAGATGGCGGCGACGGCGGCCGCAGTGGTGGCCGAGGAGGACACGGAGCTGCGGGACCTGCTGGTGCAGACGCTGGAGAACAGCGGGG
TCCTGAACCGCATCAAGGCTGAACTCCGAGCAGCTGTGTTTTTAGCACTAGAGGAGCAAGAAAAAGTAGAGAACAAAACTCCTTTAGTTA
ATGAGAGCCTGAAAAAGTTTTTAAATACCAAAGACGGTCGTTTAGTGGCTAGTCTTGTTGCAGAATTTCTTCAGTTTTTTAACCTTGACT
TTACTTTGGCTGTTTTTCAACCTGAAACTAGCACAACCTTTTTGCTACTTGATGAGATATCACAGCGCAACCGTCAGCTGCCGTCAGATG
GTAAAAAGATGGTGCATGTGCAGGATTTTACTGCTTTTTGGGATAAGGCATCAGAGACCCCAACTCTACAAGGCCTTTCCTTTACTGTCA
GACCTGGCGAATTGTTAGCTGTGGTCGGCCCCGTGGGAGCAGGGAAGTCATCACTGTTAAGTGCCGTGCTCGGGGAATTGGCCCCAAGTC
ACGGGCTGGTCAGCGTGCATGGAAGAATTGCCTATGTGTCTCAGCAGCCCTGGGTGTTCTCGGGAACTCTGAGGAGTAATATTTTATTTG
GGAAGAAATACGAAAAGGAACGATATGAAAAAGTCATAAAGGCTTGTGCTCTGAAAAAGGATTTACAGCTGTTGGAGGATGGTGATCTGA
CTGTGATAGGAGATCGGGGAACCACGCTGAGTGGAGGGCAGAAAGCACGGGTAAACCTTGCAAGAGCAGTGTATCAAGATGCTGACATCT
ATCTCCTGGACGATCCTCTCAGTGCAGTAGATGCGGAAGTTAGCAGACACTTGTTCGAACTGTGTATTTGTCAAATTTTGCATGAGAAGA
TCACAATTTTAGTGACTCATCAGTTGCAGTACCTCAAAGCTGCAAGTCAGATTCTGATATTGAAAGATGGTAAAATGGTGCAGAAGGGGA
CTTACACTGAGTTCCTAAAATCTGGTATAGATTTTGGCTCCCTTTTAAAGAAGGATAATGAGGAAAGTGAACAACCTCCAGTTCCAGGAA
CTCCCACACTAAGGAATCGTACCTTCTCAGAGTCTTCGGTTTGGTCTCAACAATCTTCTAGACCCTCCTTGAAAGATGGTGCTCTGGAGA
GCCAAGATACAGAGAATGTCCCAGTTACACTATCAGAGGAGAACCGTTCTGAAGGAAAAGTTGGTTTTCAGGCCTATAAGAATTACTTCA
GAGCTGGTGCTCACTGGATTGTCTTCATTTTCCTTATTCTCCTAAACACTGCAGCTCAGGTTGCCTATGTGCTTCAAGATTGGTGGCTTT
CATACTGGGCAAACAAACAAAGTATGCTAAATGTCACTGTAAATGGAGGAGGAAATGTAACCGAGAAGCTAGATCTTAACTGGTACTTAG
GAATTTATTCAGGTTTAACTGTAGCTACCGTTCTTTTTGGCATAGCAAGATCTCTATTGGTATTCTACGTCCTTGTTAACTCTTCACAAA
CTTTGCACAACAAAATGTTTGAGTCAATTCTGAAAGCTCCGGTATTATTCTTTGATAGAAATCCAATAGGAAGAATTTTAAATCGTTTCT
CCAAAGACATTGGACACTTGGATGATTTGCTGCCGCTGACGTTTTTAGATTTCATCCAGACATTGCTACAAGTGGTTGGTGTGGTCTCTG
TGGCTGTGGCCGTGATTCCTTGGATCGCAATACCCTTGGTTCCCCTTGGAATCATTTTCATTTTTCTTCGGCGATATTTTTTGGAAACGT
CAAGAGATGTGAAGCGCCTGGAATCTACAACTCGGAGTCCAGTGTTTTCCCACTTATCATCTTCTCTCCAGGGGCTCTGGACCATCCGGG
CATACAAAGCAGAAGAGAGGTGTCAGGAACTGTTTGATGCACACCAGGATTTACATTCAGAGGCTTGGTTCTTGTTTTTGACAACGTCCC
GCTGGTTTGCCGTCCGTCTGGATGCCATCTGTGCCATGTTTGTCATCATCGTTGCCTTTGGGTCCCTGATTCTGGCAAAAACTCTGGATG
CCGGGCAGGTTGGTTTGGCACTGTCCTATGCCCTCACGCTCATGGGGATGTTTCAGTGGTGTGTTCGACAAAGTGCTGAAGTTGAGAATA
TGATGATCTCAGTAGAAAGGGTCATTGAATACACAGACCTTGAAAAAGAAGCACCTTGGGAATATCAGAAACGCCCACCACCAGCCTGGC
CCCATGAAGGAGTGATAATCTTTGACAATGTGAACTTCATGTACAGTCCAGGTGGGCCTCTGGTACTGAAGCATCTGACAGCACTCATTA
AATCACAAGAAAAGGTTGGCATTGTGGGAAGAACCGGAGCTGGAAAAAGTTCCCTCATCTCAGCCCTTTTTAGATTGTCAGAACCCGAAG
GTAAAATTTGGATTGATAAGATCTTGACAACTGAAATTGGACTTCACGATTTAAGGAAGAAGATGTCAATCATACCTCAGGAACCTGTTT
TGTTCACTGGAACAATGAGGAAAAACCTGGATCCCTTTAATGAGCACACGGATGAGGAACTGTGGAATGCCTTACAAGAGGTACAACTTA
AAGAAACCATTGAAGATCTTCCTGGTAAAATGGATACTGAATTAGCAGAATCAGGATCCAATTTTAGTGTTGGACAAAGACAACTGGTGT
GCCTTGCCAGGGCAATTCTCAGGAAAAATCAGATATTGATTATTGATGAAGCGACGGCAAATGTGGATCCAAGAACTGATGAGTTAATAC
AAAAAAAAATCCGGGAGAAATTTGCCCACTGCACCGTGCTAACCATTGCACACAGATTGAACACCATTATTGACAGCGACAAGATAATGG
TTTTAGATTCAGGAAGACTGAAAGAATATGATGAGCCGTATGTTTTGCTGCAAAATAAAGAGAGCCTATTTTACAAGATGGTGCAACAAC
TGGGCAAGGCAGAAGCCGCTGCCCTCACTGAAACAGCAAAACAGGTATACTTCAAAAGAAATTATCCACATATTGGTCACACTGACCACA
TGGTTACAAACACTTCCAATGGACAGCCCTCGACCTTAACTATTTTCGAGACAGCACTGTGAATCCAACCAAAATGTCAAGTCCGTTCCG
AAGGCATTTTCCACTAGTTTTTGGACTATGTAAACCACATTGTACTTTTTTTTACTTTGGCAACAAATATTTATACATACAAGATGCTAG
TTCATTTGAATATTTCTCCCAACTTATCCAAGGATCTCCAGCTCTAACAAAATGGTTTATTTTTATTTAAATGTCAATAGTTGTTTTTTA
AAATCCAAATCAGAGGTGCAGGCCACCAGTTAAATGCCGTCTATCAGGTTTTGTGCCTTAAGAGACTACAGAGTCAAAGCTCATTTTTAA
AGGAGTAGGACAAAGTTGTCACAGGTTTTTGTTGTTGTTTTTATTGCCCCCAAAATTACATGTTAATTTCCATTTATATCAGGGATTCTA
TTTACTTGAAGACTGTGAAGTTGCCATTTTGTCTCATTGTTTTCTTTGACATAACTAGGATCCATTATTTCCCCTGAAGGCTTCTTGTTA
GAAAATAGTACAGTTACAACCAATAGGAACAACAAAAAGAAAAAGTTTGTGACATTGTAGTAGGGAGTGTGTACCCCTTACTCCCCATCA
AAAAAAAAAATGGATACATGGTTAAAGGATAGAAGGGCAATATTTTATCATATGTTCTAAAAGAGAAGGAAGAGAAAATACTACTTTCTC
AAAATGGAAGCCCTTAAAGGTGCTTTGATACTGAAGGACACAAATGTGACCGTCCATCCTCCTTTAGAGTTGCATGACTTGGACACGGTA
ACTGTTGCAGTTTTAGACTCAGCATTGTGACACTTCCCAAGAAGGCCAAACCTCTAACCGACATTCCTGAAATACGTGGCATTATTCTTT
TTTGGATTTCTCATTTATGGAAGGCTAACCCTCTGTTGACTGTAAGCCTTTTGGTTTGGGCTGTATTGAAATCCTTTCTAAATTGCATGA
ATAGGCTCTGCTAACGTGATGAGACAAACTGAAAATTATTGCAAGCATTGACTATAATTATGCAGTACGTTCTCAGGATGCATCCAGGGG
TTCATTTTCATGAGCCTGTCCAGGTTAGTTTACTCCTGACCACTAATAGCATTGTCATTTGGGCTTTCTGTTGAATGAATCAACAAACCA
CAATACTTCCTGGGACCTTTTGTACTTTATTTGAACTATGAGTCTTTAATTTTTCCTGATGATGGTGGCTGTAATATGTTGAGTTCAGTT
TACTAAAGGTTTTACTATTATGGTTTGAAGTGGAGTCTCATGACCTCTCAGAATAAGGTGTCACCTCCCTGAAATTGCATATATGTATAT
AGACATGCACACGTGTGCATTTGTTTGTATACATATATTTGTCCTTCGTATAGCAAGTTTTTTGCTCATCAGCAGAGAGCAACAGATGTT
TTATTGAGTGAAGCCTTAAAAAGCACACACCACACACAGCTAACTGCCAAAATACATTGACCGTAGTAGCTGTTCAACTCCTAGTACTTA
GAAATACACGTATGGTTAATGTTCAGTCCAACAAACCACACACAGTAAATGTTTATTAATAGTCATGGTTCGTATTTTAGGTGACTGAAA
TTGCATCAGTGATCATAATGAGGTTTGTTAAAACGATAGCTATATTCAAAATGTCTATATGTTTATTTGGACTTTTGAGGTTAAAGACAG
TCATATAAACGTCCTGTTTCTGTTTTAATGTTATCATAGAATTTTTTAATGAAACTAAATTCAATTGAAATAAATGATAGTTTTCATCTC
CATTCA

>30254_30254_1_FGFR1OP-ABCC4_FGFR1OP_chr6_167417299_ENST00000349556_ABCC4_chr13_95847191_ENST00000376887_length(amino acids)=1038AA_BP=100
MAATAAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNESLKKFLNTKDGRLVASLVAEFLQFFNLDFT
LAVFQPETSTTFLLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHG
LVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYL
LDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEESEQPPVPGTP
TLRNRTFSESSVWSQQSSRPSLKDGALESQDTENVPVTLSEENRSEGKVGFQAYKNYFRAGAHWIVFIFLILLNTAAQVAYVLQDWWLSY
WANKQSMLNVTVNGGGNVTEKLDLNWYLGIYSGLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSK
DIGHLDDLLPLTFLDFIQTLLQVVGVVSVAVAVIPWIAIPLVPLGIIFIFLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAY
KAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAMFVIIVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMM
ISVERVIEYTDLEKEAPWEYQKRPPPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGK
IWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQLVCL
ARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNKESLFYKMVQQLG
KAEAAALTETAKQVYFKRNYPHIGHTDHMVTNTSNGQPSTLTIFETAL

--------------------------------------------------------------
>30254_30254_2_FGFR1OP-ABCC4_FGFR1OP_chr6_167417299_ENST00000349556_ABCC4_chr13_95847191_ENST00000412704_length(transcript)=4727nt_BP=305nt
GCAAGATGGCGGCGACGGCGGCCGCAGTGGTGGCCGAGGAGGACACGGAGCTGCGGGACCTGCTGGTGCAGACGCTGGAGAACAGCGGGG
TCCTGAACCGCATCAAGGCTGAACTCCGAGCAGCTGTGTTTTTAGCACTAGAGGAGCAAGAAAAAGTAGAGAACAAAACTCCTTTAGTTA
ATGAGAGCCTGAAAAAGTTTTTAAATACCAAAGACGGTCGTTTAGTGGCTAGTCTTGTTGCAGAATTTCTTCAGTTTTTTAACCTTGACT
TTACTTTGGCTGTTTTTCAACCTGAAACTAGCACAACCTTTTTGCTACTTGATGAGATATCACAGCGCAACCGTCAGCTGCCGTCAGATG
GTAAAAAGATGGTGCATGTGCAGGATTTTACTGCTTTTTGGGATAAGGCATCAGAGACCCCAACTCTACAAGGCCTTTCCTTTACTGTCA
GACCTGGCGAATTGTTAGCTGTGGTCGGCCCCGTGGGAGCAGGGAAGTCATCACTGTTAAGTGCCGTGCTCGGGGAATTGGCCCCAAGTC
ACGGGCTGGTCAGCGTGCATGGAAGAATTGCCTATGTGTCTCAGCAGCCCTGGGTGTTCTCGGGAACTCTGAGGAGTAATATTTTATTTG
GGAAGAAATACGAAAAGGAACGATATGAAAAAGTCATAAAGGCTTGTGCTCTGAAAAAGGATTTACAGCTGTTGGAGGATGGTGATCTGA
CTGTGATAGGAGATCGGGGAACCACGCTGAGTGGAGGGCAGAAAGCACGGGTAAACCTTGCAAGAGCAGTGTATCAAGATGCTGACATCT
ATCTCCTGGACGATCCTCTCAGTGCAGTAGATGCGGAAGTTAGCAGACACTTGTTCGAACTGTGTATTTGTCAAATTTTGCATGAGAAGA
TCACAATTTTAGTGACTCATCAGTTGCAGTACCTCAAAGCTGCAAGTCAGATTCTGATATTGAAAGATGGTAAAATGGTGCAGAAGGGGA
CTTACACTGAGTTCCTAAAATCTGGTATAGATTTTGGCTCCCTTTTAAAGAAGGATAATGAGGAAAGTGAACAACCTCCAGTTCCAGGAA
CTCCCACACTAAGGAATCGTACCTTCTCAGAGTCTTCGGTTTGGTCTCAACAATCTTCTAGACCCTCCTTGAAAGATGGTGCTCTGGAGA
GCCAAGATGTTGCCTATGTGCTTCAAGATTGGTGGCTTTCATACTGGGCAAACAAACAAAGTATGCTAAATGTCACTGTAAATGGAGGAG
GAAATGTAACCGAGAAGCTAGATCTTAACTGGTACTTAGGAATTTATTCAGGTTTAACTGTAGCTACCGTTCTTTTTGGCATAGCAAGAT
CTCTATTGGTATTCTACGTCCTTGTTAACTCTTCACAAACTTTGCACAACAAAATGTTTGAGTCAATTCTGAAAGCTCCGGTATTATTCT
TTGATAGAAATCCAATAGGAAGAATTTTAAATCGTTTCTCCAAAGACATTGGACACTTGGATGATTTGCTGCCGCTGACGTTTTTAGATT
TCATCCAGACATTGCTACAAGTGGTTGGTGTGGTCTCTGTGGCTGTGGCCGTGATTCCTTGGATCGCAATACCCTTGGTTCCCCTTGGAA
TCATTTTCATTTTTCTTCGGCGATATTTTTTGGAAACGTCAAGAGATGTGAAGCGCCTGGAATCTACAACTCGGAGTCCAGTGTTTTCCC
ACTTATCATCTTCTCTCCAGGGGCTCTGGACCATCCGGGCATACAAAGCAGAAGAGAGGTGTCAGGAACTGTTTGATGCACACCAGGATT
TACATTCAGAGGCTTGGTTCTTGTTTTTGACAACGTCCCGCTGGTTTGCCGTCCGTCTGGATGCCATCTGTGCCATGTTTGTCATCATCG
TTGCCTTTGGGTCCCTGATTCTGGCAAAAACTCTGGATGCCGGGCAGGTTGGTTTGGCACTGTCCTATGCCCTCACGCTCATGGGGATGT
TTCAGTGGTGTGTTCGACAAAGTGCTGAAGTTGAGAATATGATGATCTCAGTAGAAAGGGTCATTGAATACACAGACCTTGAAAAAGAAG
CACCTTGGGAATATCAGAAACGCCCACCACCAGCCTGGCCCCATGAAGGAGTGATAATCTTTGACAATGTGAACTTCATGTACAGTCCAG
GTGGGCCTCTGGTACTGAAGCATCTGACAGCACTCATTAAATCACAAGAAAAGGTTGGCATTGTGGGAAGAACCGGAGCTGGAAAAAGTT
CCCTCATCTCAGCCCTTTTTAGATTGTCAGAACCCGAAGGTAAAATTTGGATTGATAAGATCTTGACAACTGAAATTGGACTTCACGATT
TAAGGAAGAAGATGTCAATCATACCTCAGGAACCTGTTTTGTTCACTGGAACAATGAGGAAAAACCTGGATCCCTTTAATGAGCACACGG
ATGAGGAACTGTGGAATGCCTTACAAGAGGTACAACTTAAAGAAACCATTGAAGATCTTCCTGGTAAAATGGATACTGAATTAGCAGAAT
CAGGATCCAATTTTAGTGTTGGACAAAGACAACTGGTGTGCCTTGCCAGGGCAATTCTCAGGAAAAATCAGATATTGATTATTGATGAAG
CGACGGCAAATGTGGATCCAAGAACTGATGAGTTAATACAAAAAAAAATCCGGGAGAAATTTGCCCACTGCACCGTGCTAACCATTGCAC
ACAGATTGAACACCATTATTGACAGCGACAAGATAATGGTTTTAGATTCAGGAAGACTGAAAGAATATGATGAGCCGTATGTTTTGCTGC
AAAATAAAGAGAGCCTATTTTACAAGATGGTGCAACAACTGGGCAAGGCAGAAGCCGCTGCCCTCACTGAAACAGCAAAACAGGTATACT
TCAAAAGAAATTATCCACATATTGGTCACACTGACCACATGGTTACAAACACTTCCAATGGACAGCCCTCGACCTTAACTATTTTCGAGA
CAGCACTGTGAATCCAACCAAAATGTCAAGTCCGTTCCGAAGGCATTTTCCACTAGTTTTTGGACTATGTAAACCACATTGTACTTTTTT
TTACTTTGGCAACAAATATTTATACATACAAGATGCTAGTTCATTTGAATATTTCTCCCAACTTATCCAAGGATCTCCAGCTCTAACAAA
ATGGTTTATTTTTATTTAAATGTCAATAGTTGTTTTTTAAAATCCAAATCAGAGGTGCAGGCCACCAGTTAAATGCCGTCTATCAGGTTT
TGTGCCTTAAGAGACTACAGAGTCAAAGCTCATTTTTAAAGGAGTAGGACAAAGTTGTCACAGGTTTTTGTTGTTGTTTTTATTGCCCCC
AAAATTACATGTTAATTTCCATTTATATCAGGGATTCTATTTACTTGAAGACTGTGAAGTTGCCATTTTGTCTCATTGTTTTCTTTGACA
TAACTAGGATCCATTATTTCCCCTGAAGGCTTCTTGTTAGAAAATAGTACAGTTACAACCAATAGGAACAACAAAAAGAAAAAGTTTGTG
ACATTGTAGTAGGGAGTGTGTACCCCTTACTCCCCATCAAAAAAAAAAATGGATACATGGTTAAAGGATAGAAGGGCAATATTTTATCAT
ATGTTCTAAAAGAGAAGGAAGAGAAAATACTACTTTCTCAAAATGGAAGCCCTTAAAGGTGCTTTGATACTGAAGGACACAAATGTGACC
GTCCATCCTCCTTTAGAGTTGCATGACTTGGACACGGTAACTGTTGCAGTTTTAGACTCAGCATTGTGACACTTCCCAAGAAGGCCAAAC
CTCTAACCGACATTCCTGAAATACGTGGCATTATTCTTTTTTGGATTTCTCATTTATGGAAGGCTAACCCTCTGTTGACTGTAAGCCTTT
TGGTTTGGGCTGTATTGAAATCCTTTCTAAATTGCATGAATAGGCTCTGCTAACGTGATGAGACAAACTGAAAATTATTGCAAGCATTGA
CTATAATTATGCAGTACGTTCTCAGGATGCATCCAGGGGTTCATTTTCATGAGCCTGTCCAGGTTAGTTTACTCCTGACCACTAATAGCA
TTGTCATTTGGGCTTTCTGTTGAATGAATCAACAAACCACAATACTTCCTGGGACCTTTTGTACTTTATTTGAACTATGAGTCTTTAATT
TTTCCTGATGATGGTGGCTGTAATATGTTGAGTTCAGTTTACTAAAGGTTTTACTATTATGGTTTGAAGTGGAGTCTCATGACCTCTCAG
AATAAGGTGTCACCTCCCTGAAATTGCATATATGTATATAGACATGCACACGTGTGCATTTGTTTGTATACATATATTTGTCCTTCGTAT
AGCAAGTTTTTTGCTCATCAGCAGAGAGCAACAGATGTTTTATTGAGTGAAGCCTTAAAAAGCACACACCACACACAGCTAACTGCCAAA
ATACATTGACCGTAGTAGCTGTTCAACTCCTAGTACTTAGAAATACACGTATGGTTAATGTTCAGTCCAACAAACCACACACAGTAAATG
TTTATTAATAGTCATGGTTCGTATTTTAGGTGACTGAAATTGCATCAGTGATCATAATGAGGTTTGTTAAAACGATAGCTATATTCAAAA
TGTCTATATGTTTATTTGGACTTTTGAGGTTAAAGACAGTCATATAAACGTCCTGTTTCTGTTTTAATGTTATCATAGAATTTTTTAATG
AAACTAAATTCAATTGAAATAAATGATAGTTTTCATCTCCATTCAGA

>30254_30254_2_FGFR1OP-ABCC4_FGFR1OP_chr6_167417299_ENST00000349556_ABCC4_chr13_95847191_ENST00000412704_length(amino acids)=991AA_BP=100
MAATAAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNESLKKFLNTKDGRLVASLVAEFLQFFNLDFT
LAVFQPETSTTFLLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHG
LVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYL
LDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEESEQPPVPGTP
TLRNRTFSESSVWSQQSSRPSLKDGALESQDVAYVLQDWWLSYWANKQSMLNVTVNGGGNVTEKLDLNWYLGIYSGLTVATVLFGIARSL
LVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDLLPLTFLDFIQTLLQVVGVVSVAVAVIPWIAIPLVPLGII
FIFLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAMFVIIVA
FGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIEYTDLEKEAPWEYQKRPPPAWPHEGVIIFDNVNFMYSPGG
PLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDE
ELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHR
LNTIIDSDKIMVLDSGRLKEYDEPYVLLQNKESLFYKMVQQLGKAEAAALTETAKQVYFKRNYPHIGHTDHMVTNTSNGQPSTLTIFETA
L

--------------------------------------------------------------
>30254_30254_3_FGFR1OP-ABCC4_FGFR1OP_chr6_167417299_ENST00000349556_ABCC4_chr13_95847191_ENST00000431522_length(transcript)=2088nt_BP=305nt
GCAAGATGGCGGCGACGGCGGCCGCAGTGGTGGCCGAGGAGGACACGGAGCTGCGGGACCTGCTGGTGCAGACGCTGGAGAACAGCGGGG
TCCTGAACCGCATCAAGGCTGAACTCCGAGCAGCTGTGTTTTTAGCACTAGAGGAGCAAGAAAAAGTAGAGAACAAAACTCCTTTAGTTA
ATGAGAGCCTGAAAAAGTTTTTAAATACCAAAGACGGTCGTTTAGTGGCTAGTCTTGTTGCAGAATTTCTTCAGTTTTTTAACCTTGACT
TTACTTTGGCTGTTTTTCAACCTGAAACTAGCACAACCTTTTTGCTACTTGATGAGATATCACAGCGCAACCGTCAGCTGCCGTCAGATG
GTAAAAAGATGGTGCATGTGCAGGATTTTACTGCTTTTTGGGATAAGGCATCAGAGACCCCAACTCTACAAGGCCTTTCCTTTACTGTCA
GACCTGGCGAATTGTTAGCTGTGGTCGGCCCCGTGGGAGCAGGGAAGTCATCACTGTTAAGTGCCGTGCTCGGGGAATTGGCCCCAAGTC
ACGGGCTGGTCAGCGTGCATGGAAGAATTGCCTATGTGTCTCAGCAGCCCTGGGTGTTCTCGGGAACTCTGAGGAGTAATATTTTATTTG
GGAAGAAATACGAAAAGGAACGATATGAAAAAGTCATAAAGGCTTGTGCTCTGAAAAAGGATTTACAGCTGTTGGAGGATGGTGATCTGA
CTGTGATAGGAGATCGGGGAACCACGCTGAGTGGAGGGCAGAAAGCACGGGTAAACCTTGCAAGAGCAGTGTATCAAGATGCTGACATCT
ATCTCCTGGACGATCCTCTCAGTGCAGTAGATGCGGAAGTTAGCAGACACTTGTTCGAACTGTGTATTTGTCAAATTTTGCATGAGAAGA
TCACAATTTTAGTGACTCATCAGTTGCAGTACCTCAAAGCTGCAAGTCAGATTCTGATATTGAAAGATGGTAAAATGGTGCAGAAGGGGA
CTTACACTGAGTTCCTAAAATCTGGTATAGATTTTGGCTCCCTTTTAAAGAAGGATAATGAGGAAAGTGAACAACCTCCAGTTCCAGGAA
CTCCCACACTAAGGAATCGTACCTTCTCAGAGTCTTCGGTTTGGTCTCAACAATCTTCTAGACCCTCCTTGAAAGATGGTGCTCTGGAGA
GCCAAGATACAGAGAATGTCCCAGTTACACTATCAGAGGAGAACCGTTCTGAAGGAAAAGTTGGTTTTCAGGCCTATAAGAATTACTTCA
GAGCTGGTGCTCACTGGATTGTCTTCATTTTCCTTATTCTCCTAAACACTGCAGCTCAGGTTGCCTATGTGCTTCAAGATTGGTGGCTTT
CATACTGGGCAAACAAACAAAGTATGCTAAATGTCACTGTAAATGGAGGAGGAAATGTAACCGAGAAGCTAGATCTTAACTGGTACTTAG
GAATTTATTCAGGTTTAACTGTAGCTACCGTTCTTTTTGGCATAGCAAGATCTCTATTGGTATTCTACGTCCTTGTTAACTCTTCACAAA
CTTTGCACAACAAAATGTTTGAGTCAATTCTGAAAGCTCCGGTATTATTCTTTGATAGAAATCCAATAGGAAGAATTTTAAATCGTTTCT
CCAAAGACATTGGACACTTGGATGATTTGCTGCCGCTGACGTTTTTAGATTTCATCCAGAGATGGGATCTCGCTGTGTTGTCCTGGCTGG
TCTCAAACTCCTAGGCTCAAGCAATCCTCCTCCCTCCTCAAGCAAACCTCAGTGCTGGGATTATAGGCATGAGCCACTGTACCTGGCTAA
ATGTTGTTTTTTTGATATTCAATTTTTGTTTATAGAATTTTCATTTGTTTTGCTCTTATACTTTTCATCTTTTTATGTTTATTGACCAAT
TAAATATCATTTGGGTAAGCACCTATTTAAGTGTCTTAACAATTTTTCTATTGAGTACTCTGGGTTTTTGTTTTGTTTTTCTTACTGATT
TGTAGAATTCTTTATGTATTCTGAATTGCAGATACCTTCCTTCTGTACTAATGCTTATCTTTTTAGCCCTGTAATATTGTGTTTTCATAA
ACATACTTATCAATCTTT

>30254_30254_3_FGFR1OP-ABCC4_FGFR1OP_chr6_167417299_ENST00000349556_ABCC4_chr13_95847191_ENST00000431522_length(amino acids)=572AA_BP=100
MAATAAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNESLKKFLNTKDGRLVASLVAEFLQFFNLDFT
LAVFQPETSTTFLLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHG
LVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYL
LDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEESEQPPVPGTP
TLRNRTFSESSVWSQQSSRPSLKDGALESQDTENVPVTLSEENRSEGKVGFQAYKNYFRAGAHWIVFIFLILLNTAAQVAYVLQDWWLSY
WANKQSMLNVTVNGGGNVTEKLDLNWYLGIYSGLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSK
DIGHLDDLLPLTFLDFIQRWDLAVLSWLVSNS

--------------------------------------------------------------
>30254_30254_4_FGFR1OP-ABCC4_FGFR1OP_chr6_167417299_ENST00000349556_ABCC4_chr13_95847191_ENST00000536256_length(transcript)=2090nt_BP=305nt
GCAAGATGGCGGCGACGGCGGCCGCAGTGGTGGCCGAGGAGGACACGGAGCTGCGGGACCTGCTGGTGCAGACGCTGGAGAACAGCGGGG
TCCTGAACCGCATCAAGGCTGAACTCCGAGCAGCTGTGTTTTTAGCACTAGAGGAGCAAGAAAAAGTAGAGAACAAAACTCCTTTAGTTA
ATGAGAGCCTGAAAAAGTTTTTAAATACCAAAGACGGTCGTTTAGTGGCTAGTCTTGTTGCAGAATTTCTTCAGTTTTTTAACCTTGACT
TTACTTTGGCTGTTTTTCAACCTGAAACTAGCACAACCTTTTTGCTACTTGATGAGATATCACAGCGCAACCGTCAGCTGCCGTCAGATG
GTAAAAAGATGGTGCATGTGCAGGATTTTACTGCTTTTTGGGATAAGGCATCAGAGACCCCAACTCTACAAGGCCTTTCCTTTACTGTCA
GACCTGGCGAATTGTTAGCTGTGGTCGGCCCCGTGGGAGCAGGGAAGTCATCACTGTTAAGTGCCGTGCTCGGGGAATTGGCCCCAAGTC
ACGGGCTGGTCAGCGTGCATGGAAGAATTGCCTATGTGTCTCAGCAGCCCTGGGTGTTCTCGGGAACTCTGAGGAGTAATATTTTATTTG
GGAAGAAATACGAAAAGGAACGATATGAAAAAGTCATAAAGGCTTGTGCTCTGAAAAAGGATTTACAGCTGTTGGAGGATGGTGATCTGA
CTGTGATAGGAGATCGGGGAACCACGCTGAGTGGAGGGCAGAAAGCACGGGTAAACCTTGCAAGAGCAGTGTATCAAGATGCTGACATCT
ATCTCCTGGACGATCCTCTCAGTGCAGTAGATGCGGAAGTTAGCAGACACTTGTTCGAACTGTGTATTTGTCAAATTTTGCATGAGAAGA
TCACAATTTTAGTGACTCATCAGTTGCAGTACCTCAAAGCTGCAAGTCAGATTCTGATATTGAAAGATGGTAAAATGGTGCAGAAGGGGA
CTTACACTGAGTTCCTAAAATCTGGTATAGATTTTGGCTCCCTTTTAAAGAAGGATAATGAGGAAAGTGAACAACCTCCAGTTCCAGGAA
CTCCCACACTAAGGAATCGTACCTTCTCAGAGTCTTCGGTTTGGTCTCAACAATCTTCTAGACCCTCCTTGAAAGATGGTGCTCTGGAGA
GCCAAGATACAGAGAATGTCCCAGTTACACTATCAGAGGAGAACCGTTCTGAAGGAAAAGTTGGTTTTCAGGCCTATAAGAATTACTTCA
GAGCTGGTGCTCACTGGATTGTCTTCATTTTCCTTATTCTCCTAAACACTGCAGCTCAGGTTGCCTATGTGCTTCAAGATTGGTGGCTTT
CATACTGGGCAAACAAACAAAGTATGCTAAATGTCACTGTAAATGGAGGAGGAAATGTAACCGAGAAGCTAGATCTTAACTGGTACTTAG
GAATTTATTCAGGTTTAACTGTAGCTACCGTTCTTTTTGGCATAGCAAGATCTCTATTGGTATTCTACGTCCTTGTTAACTCTTCACAAA
CTTTGCACAACAAAATGTTTGAGTCAATTCTGAAAGCTCCGGTATTATTCTTTGATAGAAATCCAATAGGAAGAATTTTAAATCGTTTCT
CCAAAGACATTGGACACTTGGATGATTTGCTGCCGCTGACGTTTTTAGATTTCATCCAGAGATGGGATCTCGCTGTGTTGTCCTGGCTGG
TCTCAAACTCCTAGGCTCAAGCAATCCTCCTCCCTCCTCAAGCAAACCTCAGTGCTGGGATTATAGGCATGAGCCACTGTACCTGGCTAA
ATGTTGTTTTTTTGATATTCAATTTTTGTTTATAGAATTTTCATTTGTTTTGCTCTTATACTTTTCATCTTTTTATGTTTATTGACCAAT
TAAATATCATTTGGGTAAGCACCTATTTAAGTGTCTTAACAATTTTTCTATTGAGTACTCTGGGTTTTTGTTTTGTTTTTCTTACTGATT
TGTAGAATTCTTTATGTATTCTGAATTGCAGATACCTTCCTTCTGTACTAATGCTTATCTTTTTAGCCCTGTAATATTGTGTTTTCATAA
ACATACTTATCAATCTTTTC

>30254_30254_4_FGFR1OP-ABCC4_FGFR1OP_chr6_167417299_ENST00000349556_ABCC4_chr13_95847191_ENST00000536256_length(amino acids)=572AA_BP=100
MAATAAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNESLKKFLNTKDGRLVASLVAEFLQFFNLDFT
LAVFQPETSTTFLLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHG
LVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYL
LDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEESEQPPVPGTP
TLRNRTFSESSVWSQQSSRPSLKDGALESQDTENVPVTLSEENRSEGKVGFQAYKNYFRAGAHWIVFIFLILLNTAAQVAYVLQDWWLSY
WANKQSMLNVTVNGGGNVTEKLDLNWYLGIYSGLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSK
DIGHLDDLLPLTFLDFIQRWDLAVLSWLVSNS

--------------------------------------------------------------
>30254_30254_5_FGFR1OP-ABCC4_FGFR1OP_chr6_167417299_ENST00000366847_ABCC4_chr13_95847191_ENST00000376887_length(transcript)=5092nt_BP=531nt
CGCCGACCCTAAGTTTCGGCGCTCAGTGGTCCGGCGCTCCCCAAGGCTCGGTGTCCAGCGTCAACCCCGAGGTCTCTATGCCCCGCCTCC
CGACGCCAGGGGGCAGGGCCAGCGCGCTGCGCGTCGGGGCGGGGCTTTGGCTGCGTCGGCCGCGTAGCCCGCGCGCGGAGCGTACCCTGC
TGCGGCCGTTGGCCGTTAGCGCGGCTTCGGCGGTTGTCTTGGAGAAGCAAGATGGCGGCGACGGCGGCCGCAGTGGTGGCCGAGGAGGAC
ACGGAGCTGCGGGACCTGCTGGTGCAGACGCTGGAGAACAGCGGGGTCCTGAACCGCATCAAGGCTGAACTCCGAGCAGCTGTGTTTTTA
GCACTAGAGGAGCAAGAAAAAGTAGAGAACAAAACTCCTTTAGTTAATGAGAGCCTGAAAAAGTTTTTAAATACCAAAGACGGTCGTTTA
GTGGCTAGTCTTGTTGCAGAATTTCTTCAGTTTTTTAACCTTGACTTTACTTTGGCTGTTTTTCAACCTGAAACTAGCACAACCTTTTTG
CTACTTGATGAGATATCACAGCGCAACCGTCAGCTGCCGTCAGATGGTAAAAAGATGGTGCATGTGCAGGATTTTACTGCTTTTTGGGAT
AAGGCATCAGAGACCCCAACTCTACAAGGCCTTTCCTTTACTGTCAGACCTGGCGAATTGTTAGCTGTGGTCGGCCCCGTGGGAGCAGGG
AAGTCATCACTGTTAAGTGCCGTGCTCGGGGAATTGGCCCCAAGTCACGGGCTGGTCAGCGTGCATGGAAGAATTGCCTATGTGTCTCAG
CAGCCCTGGGTGTTCTCGGGAACTCTGAGGAGTAATATTTTATTTGGGAAGAAATACGAAAAGGAACGATATGAAAAAGTCATAAAGGCT
TGTGCTCTGAAAAAGGATTTACAGCTGTTGGAGGATGGTGATCTGACTGTGATAGGAGATCGGGGAACCACGCTGAGTGGAGGGCAGAAA
GCACGGGTAAACCTTGCAAGAGCAGTGTATCAAGATGCTGACATCTATCTCCTGGACGATCCTCTCAGTGCAGTAGATGCGGAAGTTAGC
AGACACTTGTTCGAACTGTGTATTTGTCAAATTTTGCATGAGAAGATCACAATTTTAGTGACTCATCAGTTGCAGTACCTCAAAGCTGCA
AGTCAGATTCTGATATTGAAAGATGGTAAAATGGTGCAGAAGGGGACTTACACTGAGTTCCTAAAATCTGGTATAGATTTTGGCTCCCTT
TTAAAGAAGGATAATGAGGAAAGTGAACAACCTCCAGTTCCAGGAACTCCCACACTAAGGAATCGTACCTTCTCAGAGTCTTCGGTTTGG
TCTCAACAATCTTCTAGACCCTCCTTGAAAGATGGTGCTCTGGAGAGCCAAGATACAGAGAATGTCCCAGTTACACTATCAGAGGAGAAC
CGTTCTGAAGGAAAAGTTGGTTTTCAGGCCTATAAGAATTACTTCAGAGCTGGTGCTCACTGGATTGTCTTCATTTTCCTTATTCTCCTA
AACACTGCAGCTCAGGTTGCCTATGTGCTTCAAGATTGGTGGCTTTCATACTGGGCAAACAAACAAAGTATGCTAAATGTCACTGTAAAT
GGAGGAGGAAATGTAACCGAGAAGCTAGATCTTAACTGGTACTTAGGAATTTATTCAGGTTTAACTGTAGCTACCGTTCTTTTTGGCATA
GCAAGATCTCTATTGGTATTCTACGTCCTTGTTAACTCTTCACAAACTTTGCACAACAAAATGTTTGAGTCAATTCTGAAAGCTCCGGTA
TTATTCTTTGATAGAAATCCAATAGGAAGAATTTTAAATCGTTTCTCCAAAGACATTGGACACTTGGATGATTTGCTGCCGCTGACGTTT
TTAGATTTCATCCAGACATTGCTACAAGTGGTTGGTGTGGTCTCTGTGGCTGTGGCCGTGATTCCTTGGATCGCAATACCCTTGGTTCCC
CTTGGAATCATTTTCATTTTTCTTCGGCGATATTTTTTGGAAACGTCAAGAGATGTGAAGCGCCTGGAATCTACAACTCGGAGTCCAGTG
TTTTCCCACTTATCATCTTCTCTCCAGGGGCTCTGGACCATCCGGGCATACAAAGCAGAAGAGAGGTGTCAGGAACTGTTTGATGCACAC
CAGGATTTACATTCAGAGGCTTGGTTCTTGTTTTTGACAACGTCCCGCTGGTTTGCCGTCCGTCTGGATGCCATCTGTGCCATGTTTGTC
ATCATCGTTGCCTTTGGGTCCCTGATTCTGGCAAAAACTCTGGATGCCGGGCAGGTTGGTTTGGCACTGTCCTATGCCCTCACGCTCATG
GGGATGTTTCAGTGGTGTGTTCGACAAAGTGCTGAAGTTGAGAATATGATGATCTCAGTAGAAAGGGTCATTGAATACACAGACCTTGAA
AAAGAAGCACCTTGGGAATATCAGAAACGCCCACCACCAGCCTGGCCCCATGAAGGAGTGATAATCTTTGACAATGTGAACTTCATGTAC
AGTCCAGGTGGGCCTCTGGTACTGAAGCATCTGACAGCACTCATTAAATCACAAGAAAAGGTTGGCATTGTGGGAAGAACCGGAGCTGGA
AAAAGTTCCCTCATCTCAGCCCTTTTTAGATTGTCAGAACCCGAAGGTAAAATTTGGATTGATAAGATCTTGACAACTGAAATTGGACTT
CACGATTTAAGGAAGAAGATGTCAATCATACCTCAGGAACCTGTTTTGTTCACTGGAACAATGAGGAAAAACCTGGATCCCTTTAATGAG
CACACGGATGAGGAACTGTGGAATGCCTTACAAGAGGTACAACTTAAAGAAACCATTGAAGATCTTCCTGGTAAAATGGATACTGAATTA
GCAGAATCAGGATCCAATTTTAGTGTTGGACAAAGACAACTGGTGTGCCTTGCCAGGGCAATTCTCAGGAAAAATCAGATATTGATTATT
GATGAAGCGACGGCAAATGTGGATCCAAGAACTGATGAGTTAATACAAAAAAAAATCCGGGAGAAATTTGCCCACTGCACCGTGCTAACC
ATTGCACACAGATTGAACACCATTATTGACAGCGACAAGATAATGGTTTTAGATTCAGGAAGACTGAAAGAATATGATGAGCCGTATGTT
TTGCTGCAAAATAAAGAGAGCCTATTTTACAAGATGGTGCAACAACTGGGCAAGGCAGAAGCCGCTGCCCTCACTGAAACAGCAAAACAG
GTATACTTCAAAAGAAATTATCCACATATTGGTCACACTGACCACATGGTTACAAACACTTCCAATGGACAGCCCTCGACCTTAACTATT
TTCGAGACAGCACTGTGAATCCAACCAAAATGTCAAGTCCGTTCCGAAGGCATTTTCCACTAGTTTTTGGACTATGTAAACCACATTGTA
CTTTTTTTTACTTTGGCAACAAATATTTATACATACAAGATGCTAGTTCATTTGAATATTTCTCCCAACTTATCCAAGGATCTCCAGCTC
TAACAAAATGGTTTATTTTTATTTAAATGTCAATAGTTGTTTTTTAAAATCCAAATCAGAGGTGCAGGCCACCAGTTAAATGCCGTCTAT
CAGGTTTTGTGCCTTAAGAGACTACAGAGTCAAAGCTCATTTTTAAAGGAGTAGGACAAAGTTGTCACAGGTTTTTGTTGTTGTTTTTAT
TGCCCCCAAAATTACATGTTAATTTCCATTTATATCAGGGATTCTATTTACTTGAAGACTGTGAAGTTGCCATTTTGTCTCATTGTTTTC
TTTGACATAACTAGGATCCATTATTTCCCCTGAAGGCTTCTTGTTAGAAAATAGTACAGTTACAACCAATAGGAACAACAAAAAGAAAAA
GTTTGTGACATTGTAGTAGGGAGTGTGTACCCCTTACTCCCCATCAAAAAAAAAAATGGATACATGGTTAAAGGATAGAAGGGCAATATT
TTATCATATGTTCTAAAAGAGAAGGAAGAGAAAATACTACTTTCTCAAAATGGAAGCCCTTAAAGGTGCTTTGATACTGAAGGACACAAA
TGTGACCGTCCATCCTCCTTTAGAGTTGCATGACTTGGACACGGTAACTGTTGCAGTTTTAGACTCAGCATTGTGACACTTCCCAAGAAG
GCCAAACCTCTAACCGACATTCCTGAAATACGTGGCATTATTCTTTTTTGGATTTCTCATTTATGGAAGGCTAACCCTCTGTTGACTGTA
AGCCTTTTGGTTTGGGCTGTATTGAAATCCTTTCTAAATTGCATGAATAGGCTCTGCTAACGTGATGAGACAAACTGAAAATTATTGCAA
GCATTGACTATAATTATGCAGTACGTTCTCAGGATGCATCCAGGGGTTCATTTTCATGAGCCTGTCCAGGTTAGTTTACTCCTGACCACT
AATAGCATTGTCATTTGGGCTTTCTGTTGAATGAATCAACAAACCACAATACTTCCTGGGACCTTTTGTACTTTATTTGAACTATGAGTC
TTTAATTTTTCCTGATGATGGTGGCTGTAATATGTTGAGTTCAGTTTACTAAAGGTTTTACTATTATGGTTTGAAGTGGAGTCTCATGAC
CTCTCAGAATAAGGTGTCACCTCCCTGAAATTGCATATATGTATATAGACATGCACACGTGTGCATTTGTTTGTATACATATATTTGTCC
TTCGTATAGCAAGTTTTTTGCTCATCAGCAGAGAGCAACAGATGTTTTATTGAGTGAAGCCTTAAAAAGCACACACCACACACAGCTAAC
TGCCAAAATACATTGACCGTAGTAGCTGTTCAACTCCTAGTACTTAGAAATACACGTATGGTTAATGTTCAGTCCAACAAACCACACACA
GTAAATGTTTATTAATAGTCATGGTTCGTATTTTAGGTGACTGAAATTGCATCAGTGATCATAATGAGGTTTGTTAAAACGATAGCTATA
TTCAAAATGTCTATATGTTTATTTGGACTTTTGAGGTTAAAGACAGTCATATAAACGTCCTGTTTCTGTTTTAATGTTATCATAGAATTT
TTTAATGAAACTAAATTCAATTGAAATAAATGATAGTTTTCATCTCCATTCA

>30254_30254_5_FGFR1OP-ABCC4_FGFR1OP_chr6_167417299_ENST00000366847_ABCC4_chr13_95847191_ENST00000376887_length(amino acids)=1044AA_BP=106
MSWRSKMAATAAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNESLKKFLNTKDGRLVASLVAEFLQF
FNLDFTLAVFQPETSTTFLLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGE
LAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQ
DADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEESEQP
PVPGTPTLRNRTFSESSVWSQQSSRPSLKDGALESQDTENVPVTLSEENRSEGKVGFQAYKNYFRAGAHWIVFIFLILLNTAAQVAYVLQ
DWWLSYWANKQSMLNVTVNGGGNVTEKLDLNWYLGIYSGLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRI
LNRFSKDIGHLDDLLPLTFLDFIQTLLQVVGVVSVAVAVIPWIAIPLVPLGIIFIFLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGL
WTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAMFVIIVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSA
EVENMMISVERVIEYTDLEKEAPWEYQKRPPPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRL
SEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQ
RQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNKESLFYK
MVQQLGKAEAAALTETAKQVYFKRNYPHIGHTDHMVTNTSNGQPSTLTIFETAL

--------------------------------------------------------------
>30254_30254_6_FGFR1OP-ABCC4_FGFR1OP_chr6_167417299_ENST00000366847_ABCC4_chr13_95847191_ENST00000412704_length(transcript)=4953nt_BP=531nt
CGCCGACCCTAAGTTTCGGCGCTCAGTGGTCCGGCGCTCCCCAAGGCTCGGTGTCCAGCGTCAACCCCGAGGTCTCTATGCCCCGCCTCC
CGACGCCAGGGGGCAGGGCCAGCGCGCTGCGCGTCGGGGCGGGGCTTTGGCTGCGTCGGCCGCGTAGCCCGCGCGCGGAGCGTACCCTGC
TGCGGCCGTTGGCCGTTAGCGCGGCTTCGGCGGTTGTCTTGGAGAAGCAAGATGGCGGCGACGGCGGCCGCAGTGGTGGCCGAGGAGGAC
ACGGAGCTGCGGGACCTGCTGGTGCAGACGCTGGAGAACAGCGGGGTCCTGAACCGCATCAAGGCTGAACTCCGAGCAGCTGTGTTTTTA
GCACTAGAGGAGCAAGAAAAAGTAGAGAACAAAACTCCTTTAGTTAATGAGAGCCTGAAAAAGTTTTTAAATACCAAAGACGGTCGTTTA
GTGGCTAGTCTTGTTGCAGAATTTCTTCAGTTTTTTAACCTTGACTTTACTTTGGCTGTTTTTCAACCTGAAACTAGCACAACCTTTTTG
CTACTTGATGAGATATCACAGCGCAACCGTCAGCTGCCGTCAGATGGTAAAAAGATGGTGCATGTGCAGGATTTTACTGCTTTTTGGGAT
AAGGCATCAGAGACCCCAACTCTACAAGGCCTTTCCTTTACTGTCAGACCTGGCGAATTGTTAGCTGTGGTCGGCCCCGTGGGAGCAGGG
AAGTCATCACTGTTAAGTGCCGTGCTCGGGGAATTGGCCCCAAGTCACGGGCTGGTCAGCGTGCATGGAAGAATTGCCTATGTGTCTCAG
CAGCCCTGGGTGTTCTCGGGAACTCTGAGGAGTAATATTTTATTTGGGAAGAAATACGAAAAGGAACGATATGAAAAAGTCATAAAGGCT
TGTGCTCTGAAAAAGGATTTACAGCTGTTGGAGGATGGTGATCTGACTGTGATAGGAGATCGGGGAACCACGCTGAGTGGAGGGCAGAAA
GCACGGGTAAACCTTGCAAGAGCAGTGTATCAAGATGCTGACATCTATCTCCTGGACGATCCTCTCAGTGCAGTAGATGCGGAAGTTAGC
AGACACTTGTTCGAACTGTGTATTTGTCAAATTTTGCATGAGAAGATCACAATTTTAGTGACTCATCAGTTGCAGTACCTCAAAGCTGCA
AGTCAGATTCTGATATTGAAAGATGGTAAAATGGTGCAGAAGGGGACTTACACTGAGTTCCTAAAATCTGGTATAGATTTTGGCTCCCTT
TTAAAGAAGGATAATGAGGAAAGTGAACAACCTCCAGTTCCAGGAACTCCCACACTAAGGAATCGTACCTTCTCAGAGTCTTCGGTTTGG
TCTCAACAATCTTCTAGACCCTCCTTGAAAGATGGTGCTCTGGAGAGCCAAGATGTTGCCTATGTGCTTCAAGATTGGTGGCTTTCATAC
TGGGCAAACAAACAAAGTATGCTAAATGTCACTGTAAATGGAGGAGGAAATGTAACCGAGAAGCTAGATCTTAACTGGTACTTAGGAATT
TATTCAGGTTTAACTGTAGCTACCGTTCTTTTTGGCATAGCAAGATCTCTATTGGTATTCTACGTCCTTGTTAACTCTTCACAAACTTTG
CACAACAAAATGTTTGAGTCAATTCTGAAAGCTCCGGTATTATTCTTTGATAGAAATCCAATAGGAAGAATTTTAAATCGTTTCTCCAAA
GACATTGGACACTTGGATGATTTGCTGCCGCTGACGTTTTTAGATTTCATCCAGACATTGCTACAAGTGGTTGGTGTGGTCTCTGTGGCT
GTGGCCGTGATTCCTTGGATCGCAATACCCTTGGTTCCCCTTGGAATCATTTTCATTTTTCTTCGGCGATATTTTTTGGAAACGTCAAGA
GATGTGAAGCGCCTGGAATCTACAACTCGGAGTCCAGTGTTTTCCCACTTATCATCTTCTCTCCAGGGGCTCTGGACCATCCGGGCATAC
AAAGCAGAAGAGAGGTGTCAGGAACTGTTTGATGCACACCAGGATTTACATTCAGAGGCTTGGTTCTTGTTTTTGACAACGTCCCGCTGG
TTTGCCGTCCGTCTGGATGCCATCTGTGCCATGTTTGTCATCATCGTTGCCTTTGGGTCCCTGATTCTGGCAAAAACTCTGGATGCCGGG
CAGGTTGGTTTGGCACTGTCCTATGCCCTCACGCTCATGGGGATGTTTCAGTGGTGTGTTCGACAAAGTGCTGAAGTTGAGAATATGATG
ATCTCAGTAGAAAGGGTCATTGAATACACAGACCTTGAAAAAGAAGCACCTTGGGAATATCAGAAACGCCCACCACCAGCCTGGCCCCAT
GAAGGAGTGATAATCTTTGACAATGTGAACTTCATGTACAGTCCAGGTGGGCCTCTGGTACTGAAGCATCTGACAGCACTCATTAAATCA
CAAGAAAAGGTTGGCATTGTGGGAAGAACCGGAGCTGGAAAAAGTTCCCTCATCTCAGCCCTTTTTAGATTGTCAGAACCCGAAGGTAAA
ATTTGGATTGATAAGATCTTGACAACTGAAATTGGACTTCACGATTTAAGGAAGAAGATGTCAATCATACCTCAGGAACCTGTTTTGTTC
ACTGGAACAATGAGGAAAAACCTGGATCCCTTTAATGAGCACACGGATGAGGAACTGTGGAATGCCTTACAAGAGGTACAACTTAAAGAA
ACCATTGAAGATCTTCCTGGTAAAATGGATACTGAATTAGCAGAATCAGGATCCAATTTTAGTGTTGGACAAAGACAACTGGTGTGCCTT
GCCAGGGCAATTCTCAGGAAAAATCAGATATTGATTATTGATGAAGCGACGGCAAATGTGGATCCAAGAACTGATGAGTTAATACAAAAA
AAAATCCGGGAGAAATTTGCCCACTGCACCGTGCTAACCATTGCACACAGATTGAACACCATTATTGACAGCGACAAGATAATGGTTTTA
GATTCAGGAAGACTGAAAGAATATGATGAGCCGTATGTTTTGCTGCAAAATAAAGAGAGCCTATTTTACAAGATGGTGCAACAACTGGGC
AAGGCAGAAGCCGCTGCCCTCACTGAAACAGCAAAACAGGTATACTTCAAAAGAAATTATCCACATATTGGTCACACTGACCACATGGTT
ACAAACACTTCCAATGGACAGCCCTCGACCTTAACTATTTTCGAGACAGCACTGTGAATCCAACCAAAATGTCAAGTCCGTTCCGAAGGC
ATTTTCCACTAGTTTTTGGACTATGTAAACCACATTGTACTTTTTTTTACTTTGGCAACAAATATTTATACATACAAGATGCTAGTTCAT
TTGAATATTTCTCCCAACTTATCCAAGGATCTCCAGCTCTAACAAAATGGTTTATTTTTATTTAAATGTCAATAGTTGTTTTTTAAAATC
CAAATCAGAGGTGCAGGCCACCAGTTAAATGCCGTCTATCAGGTTTTGTGCCTTAAGAGACTACAGAGTCAAAGCTCATTTTTAAAGGAG
TAGGACAAAGTTGTCACAGGTTTTTGTTGTTGTTTTTATTGCCCCCAAAATTACATGTTAATTTCCATTTATATCAGGGATTCTATTTAC
TTGAAGACTGTGAAGTTGCCATTTTGTCTCATTGTTTTCTTTGACATAACTAGGATCCATTATTTCCCCTGAAGGCTTCTTGTTAGAAAA
TAGTACAGTTACAACCAATAGGAACAACAAAAAGAAAAAGTTTGTGACATTGTAGTAGGGAGTGTGTACCCCTTACTCCCCATCAAAAAA
AAAAATGGATACATGGTTAAAGGATAGAAGGGCAATATTTTATCATATGTTCTAAAAGAGAAGGAAGAGAAAATACTACTTTCTCAAAAT
GGAAGCCCTTAAAGGTGCTTTGATACTGAAGGACACAAATGTGACCGTCCATCCTCCTTTAGAGTTGCATGACTTGGACACGGTAACTGT
TGCAGTTTTAGACTCAGCATTGTGACACTTCCCAAGAAGGCCAAACCTCTAACCGACATTCCTGAAATACGTGGCATTATTCTTTTTTGG
ATTTCTCATTTATGGAAGGCTAACCCTCTGTTGACTGTAAGCCTTTTGGTTTGGGCTGTATTGAAATCCTTTCTAAATTGCATGAATAGG
CTCTGCTAACGTGATGAGACAAACTGAAAATTATTGCAAGCATTGACTATAATTATGCAGTACGTTCTCAGGATGCATCCAGGGGTTCAT
TTTCATGAGCCTGTCCAGGTTAGTTTACTCCTGACCACTAATAGCATTGTCATTTGGGCTTTCTGTTGAATGAATCAACAAACCACAATA
CTTCCTGGGACCTTTTGTACTTTATTTGAACTATGAGTCTTTAATTTTTCCTGATGATGGTGGCTGTAATATGTTGAGTTCAGTTTACTA
AAGGTTTTACTATTATGGTTTGAAGTGGAGTCTCATGACCTCTCAGAATAAGGTGTCACCTCCCTGAAATTGCATATATGTATATAGACA
TGCACACGTGTGCATTTGTTTGTATACATATATTTGTCCTTCGTATAGCAAGTTTTTTGCTCATCAGCAGAGAGCAACAGATGTTTTATT
GAGTGAAGCCTTAAAAAGCACACACCACACACAGCTAACTGCCAAAATACATTGACCGTAGTAGCTGTTCAACTCCTAGTACTTAGAAAT
ACACGTATGGTTAATGTTCAGTCCAACAAACCACACACAGTAAATGTTTATTAATAGTCATGGTTCGTATTTTAGGTGACTGAAATTGCA
TCAGTGATCATAATGAGGTTTGTTAAAACGATAGCTATATTCAAAATGTCTATATGTTTATTTGGACTTTTGAGGTTAAAGACAGTCATA
TAAACGTCCTGTTTCTGTTTTAATGTTATCATAGAATTTTTTAATGAAACTAAATTCAATTGAAATAAATGATAGTTTTCATCTCCATTC
AGA

>30254_30254_6_FGFR1OP-ABCC4_FGFR1OP_chr6_167417299_ENST00000366847_ABCC4_chr13_95847191_ENST00000412704_length(amino acids)=997AA_BP=106
MSWRSKMAATAAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNESLKKFLNTKDGRLVASLVAEFLQF
FNLDFTLAVFQPETSTTFLLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGE
LAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQ
DADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEESEQP
PVPGTPTLRNRTFSESSVWSQQSSRPSLKDGALESQDVAYVLQDWWLSYWANKQSMLNVTVNGGGNVTEKLDLNWYLGIYSGLTVATVLF
GIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDLLPLTFLDFIQTLLQVVGVVSVAVAVIPWIAIPL
VPLGIIFIFLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAM
FVIIVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIEYTDLEKEAPWEYQKRPPPAWPHEGVIIFDNVNF
MYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPF
NEHTDEELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTV
LTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNKESLFYKMVQQLGKAEAAALTETAKQVYFKRNYPHIGHTDHMVTNTSNGQPSTL
TIFETAL

--------------------------------------------------------------
>30254_30254_7_FGFR1OP-ABCC4_FGFR1OP_chr6_167417299_ENST00000366847_ABCC4_chr13_95847191_ENST00000431522_length(transcript)=2314nt_BP=531nt
CGCCGACCCTAAGTTTCGGCGCTCAGTGGTCCGGCGCTCCCCAAGGCTCGGTGTCCAGCGTCAACCCCGAGGTCTCTATGCCCCGCCTCC
CGACGCCAGGGGGCAGGGCCAGCGCGCTGCGCGTCGGGGCGGGGCTTTGGCTGCGTCGGCCGCGTAGCCCGCGCGCGGAGCGTACCCTGC
TGCGGCCGTTGGCCGTTAGCGCGGCTTCGGCGGTTGTCTTGGAGAAGCAAGATGGCGGCGACGGCGGCCGCAGTGGTGGCCGAGGAGGAC
ACGGAGCTGCGGGACCTGCTGGTGCAGACGCTGGAGAACAGCGGGGTCCTGAACCGCATCAAGGCTGAACTCCGAGCAGCTGTGTTTTTA
GCACTAGAGGAGCAAGAAAAAGTAGAGAACAAAACTCCTTTAGTTAATGAGAGCCTGAAAAAGTTTTTAAATACCAAAGACGGTCGTTTA
GTGGCTAGTCTTGTTGCAGAATTTCTTCAGTTTTTTAACCTTGACTTTACTTTGGCTGTTTTTCAACCTGAAACTAGCACAACCTTTTTG
CTACTTGATGAGATATCACAGCGCAACCGTCAGCTGCCGTCAGATGGTAAAAAGATGGTGCATGTGCAGGATTTTACTGCTTTTTGGGAT
AAGGCATCAGAGACCCCAACTCTACAAGGCCTTTCCTTTACTGTCAGACCTGGCGAATTGTTAGCTGTGGTCGGCCCCGTGGGAGCAGGG
AAGTCATCACTGTTAAGTGCCGTGCTCGGGGAATTGGCCCCAAGTCACGGGCTGGTCAGCGTGCATGGAAGAATTGCCTATGTGTCTCAG
CAGCCCTGGGTGTTCTCGGGAACTCTGAGGAGTAATATTTTATTTGGGAAGAAATACGAAAAGGAACGATATGAAAAAGTCATAAAGGCT
TGTGCTCTGAAAAAGGATTTACAGCTGTTGGAGGATGGTGATCTGACTGTGATAGGAGATCGGGGAACCACGCTGAGTGGAGGGCAGAAA
GCACGGGTAAACCTTGCAAGAGCAGTGTATCAAGATGCTGACATCTATCTCCTGGACGATCCTCTCAGTGCAGTAGATGCGGAAGTTAGC
AGACACTTGTTCGAACTGTGTATTTGTCAAATTTTGCATGAGAAGATCACAATTTTAGTGACTCATCAGTTGCAGTACCTCAAAGCTGCA
AGTCAGATTCTGATATTGAAAGATGGTAAAATGGTGCAGAAGGGGACTTACACTGAGTTCCTAAAATCTGGTATAGATTTTGGCTCCCTT
TTAAAGAAGGATAATGAGGAAAGTGAACAACCTCCAGTTCCAGGAACTCCCACACTAAGGAATCGTACCTTCTCAGAGTCTTCGGTTTGG
TCTCAACAATCTTCTAGACCCTCCTTGAAAGATGGTGCTCTGGAGAGCCAAGATACAGAGAATGTCCCAGTTACACTATCAGAGGAGAAC
CGTTCTGAAGGAAAAGTTGGTTTTCAGGCCTATAAGAATTACTTCAGAGCTGGTGCTCACTGGATTGTCTTCATTTTCCTTATTCTCCTA
AACACTGCAGCTCAGGTTGCCTATGTGCTTCAAGATTGGTGGCTTTCATACTGGGCAAACAAACAAAGTATGCTAAATGTCACTGTAAAT
GGAGGAGGAAATGTAACCGAGAAGCTAGATCTTAACTGGTACTTAGGAATTTATTCAGGTTTAACTGTAGCTACCGTTCTTTTTGGCATA
GCAAGATCTCTATTGGTATTCTACGTCCTTGTTAACTCTTCACAAACTTTGCACAACAAAATGTTTGAGTCAATTCTGAAAGCTCCGGTA
TTATTCTTTGATAGAAATCCAATAGGAAGAATTTTAAATCGTTTCTCCAAAGACATTGGACACTTGGATGATTTGCTGCCGCTGACGTTT
TTAGATTTCATCCAGAGATGGGATCTCGCTGTGTTGTCCTGGCTGGTCTCAAACTCCTAGGCTCAAGCAATCCTCCTCCCTCCTCAAGCA
AACCTCAGTGCTGGGATTATAGGCATGAGCCACTGTACCTGGCTAAATGTTGTTTTTTTGATATTCAATTTTTGTTTATAGAATTTTCAT
TTGTTTTGCTCTTATACTTTTCATCTTTTTATGTTTATTGACCAATTAAATATCATTTGGGTAAGCACCTATTTAAGTGTCTTAACAATT
TTTCTATTGAGTACTCTGGGTTTTTGTTTTGTTTTTCTTACTGATTTGTAGAATTCTTTATGTATTCTGAATTGCAGATACCTTCCTTCT
GTACTAATGCTTATCTTTTTAGCCCTGTAATATTGTGTTTTCATAAACATACTTATCAATCTTT

>30254_30254_7_FGFR1OP-ABCC4_FGFR1OP_chr6_167417299_ENST00000366847_ABCC4_chr13_95847191_ENST00000431522_length(amino acids)=578AA_BP=106
MSWRSKMAATAAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNESLKKFLNTKDGRLVASLVAEFLQF
FNLDFTLAVFQPETSTTFLLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGE
LAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQ
DADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEESEQP
PVPGTPTLRNRTFSESSVWSQQSSRPSLKDGALESQDTENVPVTLSEENRSEGKVGFQAYKNYFRAGAHWIVFIFLILLNTAAQVAYVLQ
DWWLSYWANKQSMLNVTVNGGGNVTEKLDLNWYLGIYSGLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRI
LNRFSKDIGHLDDLLPLTFLDFIQRWDLAVLSWLVSNS

--------------------------------------------------------------
>30254_30254_8_FGFR1OP-ABCC4_FGFR1OP_chr6_167417299_ENST00000366847_ABCC4_chr13_95847191_ENST00000536256_length(transcript)=2316nt_BP=531nt
CGCCGACCCTAAGTTTCGGCGCTCAGTGGTCCGGCGCTCCCCAAGGCTCGGTGTCCAGCGTCAACCCCGAGGTCTCTATGCCCCGCCTCC
CGACGCCAGGGGGCAGGGCCAGCGCGCTGCGCGTCGGGGCGGGGCTTTGGCTGCGTCGGCCGCGTAGCCCGCGCGCGGAGCGTACCCTGC
TGCGGCCGTTGGCCGTTAGCGCGGCTTCGGCGGTTGTCTTGGAGAAGCAAGATGGCGGCGACGGCGGCCGCAGTGGTGGCCGAGGAGGAC
ACGGAGCTGCGGGACCTGCTGGTGCAGACGCTGGAGAACAGCGGGGTCCTGAACCGCATCAAGGCTGAACTCCGAGCAGCTGTGTTTTTA
GCACTAGAGGAGCAAGAAAAAGTAGAGAACAAAACTCCTTTAGTTAATGAGAGCCTGAAAAAGTTTTTAAATACCAAAGACGGTCGTTTA
GTGGCTAGTCTTGTTGCAGAATTTCTTCAGTTTTTTAACCTTGACTTTACTTTGGCTGTTTTTCAACCTGAAACTAGCACAACCTTTTTG
CTACTTGATGAGATATCACAGCGCAACCGTCAGCTGCCGTCAGATGGTAAAAAGATGGTGCATGTGCAGGATTTTACTGCTTTTTGGGAT
AAGGCATCAGAGACCCCAACTCTACAAGGCCTTTCCTTTACTGTCAGACCTGGCGAATTGTTAGCTGTGGTCGGCCCCGTGGGAGCAGGG
AAGTCATCACTGTTAAGTGCCGTGCTCGGGGAATTGGCCCCAAGTCACGGGCTGGTCAGCGTGCATGGAAGAATTGCCTATGTGTCTCAG
CAGCCCTGGGTGTTCTCGGGAACTCTGAGGAGTAATATTTTATTTGGGAAGAAATACGAAAAGGAACGATATGAAAAAGTCATAAAGGCT
TGTGCTCTGAAAAAGGATTTACAGCTGTTGGAGGATGGTGATCTGACTGTGATAGGAGATCGGGGAACCACGCTGAGTGGAGGGCAGAAA
GCACGGGTAAACCTTGCAAGAGCAGTGTATCAAGATGCTGACATCTATCTCCTGGACGATCCTCTCAGTGCAGTAGATGCGGAAGTTAGC
AGACACTTGTTCGAACTGTGTATTTGTCAAATTTTGCATGAGAAGATCACAATTTTAGTGACTCATCAGTTGCAGTACCTCAAAGCTGCA
AGTCAGATTCTGATATTGAAAGATGGTAAAATGGTGCAGAAGGGGACTTACACTGAGTTCCTAAAATCTGGTATAGATTTTGGCTCCCTT
TTAAAGAAGGATAATGAGGAAAGTGAACAACCTCCAGTTCCAGGAACTCCCACACTAAGGAATCGTACCTTCTCAGAGTCTTCGGTTTGG
TCTCAACAATCTTCTAGACCCTCCTTGAAAGATGGTGCTCTGGAGAGCCAAGATACAGAGAATGTCCCAGTTACACTATCAGAGGAGAAC
CGTTCTGAAGGAAAAGTTGGTTTTCAGGCCTATAAGAATTACTTCAGAGCTGGTGCTCACTGGATTGTCTTCATTTTCCTTATTCTCCTA
AACACTGCAGCTCAGGTTGCCTATGTGCTTCAAGATTGGTGGCTTTCATACTGGGCAAACAAACAAAGTATGCTAAATGTCACTGTAAAT
GGAGGAGGAAATGTAACCGAGAAGCTAGATCTTAACTGGTACTTAGGAATTTATTCAGGTTTAACTGTAGCTACCGTTCTTTTTGGCATA
GCAAGATCTCTATTGGTATTCTACGTCCTTGTTAACTCTTCACAAACTTTGCACAACAAAATGTTTGAGTCAATTCTGAAAGCTCCGGTA
TTATTCTTTGATAGAAATCCAATAGGAAGAATTTTAAATCGTTTCTCCAAAGACATTGGACACTTGGATGATTTGCTGCCGCTGACGTTT
TTAGATTTCATCCAGAGATGGGATCTCGCTGTGTTGTCCTGGCTGGTCTCAAACTCCTAGGCTCAAGCAATCCTCCTCCCTCCTCAAGCA
AACCTCAGTGCTGGGATTATAGGCATGAGCCACTGTACCTGGCTAAATGTTGTTTTTTTGATATTCAATTTTTGTTTATAGAATTTTCAT
TTGTTTTGCTCTTATACTTTTCATCTTTTTATGTTTATTGACCAATTAAATATCATTTGGGTAAGCACCTATTTAAGTGTCTTAACAATT
TTTCTATTGAGTACTCTGGGTTTTTGTTTTGTTTTTCTTACTGATTTGTAGAATTCTTTATGTATTCTGAATTGCAGATACCTTCCTTCT
GTACTAATGCTTATCTTTTTAGCCCTGTAATATTGTGTTTTCATAAACATACTTATCAATCTTTTC

>30254_30254_8_FGFR1OP-ABCC4_FGFR1OP_chr6_167417299_ENST00000366847_ABCC4_chr13_95847191_ENST00000536256_length(amino acids)=578AA_BP=106
MSWRSKMAATAAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNESLKKFLNTKDGRLVASLVAEFLQF
FNLDFTLAVFQPETSTTFLLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGE
LAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQ
DADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEESEQP
PVPGTPTLRNRTFSESSVWSQQSSRPSLKDGALESQDTENVPVTLSEENRSEGKVGFQAYKNYFRAGAHWIVFIFLILLNTAAQVAYVLQ
DWWLSYWANKQSMLNVTVNGGGNVTEKLDLNWYLGIYSGLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRI
LNRFSKDIGHLDDLLPLTFLDFIQRWDLAVLSWLVSNS

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Fusion Gene PPI Analysis for FGFR1OP-ABCC4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FGFR1OP-ABCC4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FGFR1OP-ABCC4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0003873Rheumatoid Arthritis1CTD_human
TgeneC0009241Cognition Disorders1CTD_human
TgeneC0009402Colorectal Carcinoma1CTD_human
TgeneC0009404Colorectal Neoplasms1CTD_human
TgeneC0013146Drug abuse1CTD_human
TgeneC0013170Drug habituation1CTD_human
TgeneC0013221Drug toxicity1CTD_human
TgeneC0013222Drug Use Disorders1CTD_human
TgeneC0014175Endometriosis1CTD_human
TgeneC0027627Neoplasm Metastasis1CTD_human
TgeneC0029231Organic Mental Disorders, Substance-Induced1CTD_human
TgeneC0033578Prostatic Neoplasms1CTD_human
TgeneC0038580Substance Dependence1CTD_human
TgeneC0038586Substance Use Disorders1CTD_human
TgeneC0041755Adverse reaction to drug1CTD_human
TgeneC0236969Substance-Related Disorders1CTD_human
TgeneC0269102Endometrioma1CTD_human
TgeneC0342257Complications of Diabetes Mellitus1CTD_human
TgeneC0376358Malignant neoplasm of prostate1CTD_human
TgeneC0740858Substance abuse problem1CTD_human
TgeneC1510472Drug Dependence1CTD_human
TgeneC4316881Prescription Drug Abuse1CTD_human