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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BAZ2A-NACA (FusionGDB2 ID:HG11176TG4666)

Fusion Gene Summary for BAZ2A-NACA

check button Fusion gene summary
Fusion gene informationFusion gene name: BAZ2A-NACA
Fusion gene ID: hg11176tg4666
HgeneTgene
Gene symbol

BAZ2A

NACA

Gene ID

11176

4666

Gene namebromodomain adjacent to zinc finger domain 2Anascent polypeptide associated complex subunit alpha
SynonymsTIP5|WALp3HSD48|NAC-alpha|NACA1|skNAC
Cytomap('BAZ2A')('NACA')

12q13.3

12q13.3

Type of geneprotein-codingprotein-coding
Descriptionbromodomain adjacent to zinc finger domain protein 2ATTF-I interacting peptide 5TTF-I-interacting protein 5transcription termination factor I-interacting protein 5nascent polypeptide-associated complex subunit alphaalpha-NAC, muscle-specific formnascent-polypeptide-associated complex alpha polypeptide
Modification date2020031320200313
UniProtAcc.

E9PAV3

Ensembl transtripts involved in fusion geneENST00000549884, ENST00000179765, 
ENST00000379441, ENST00000551812, 
ENST00000553222, 
Fusion gene scores* DoF score16 X 18 X 8=230415 X 16 X 4=960
# samples 2015
** MAII scorelog2(20/2304*10)=-3.52606881166759
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(15/960*10)=-2.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BAZ2A [Title/Abstract] AND NACA [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBAZ2A(57024560)-NACA(57118307), # samples:2
BAZ2A(57023909)-NACA(57119237), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID


check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-VQ-AA6D-01ABAZ2Achr12

57023909

-NACAchr12

57108471

-
ChimerDB4STADTCGA-VQ-AA6D-01ABAZ2Achr12

57023909

-NACAchr12

57118307

-
ChimerDB4STADTCGA-VQ-AA6D-01ABAZ2Achr12

57023909

-NACAchr12

57119124

-
ChimerDB4STADTCGA-VQ-AA6D-01ABAZ2Achr12

57023909

-NACAchr12

57119237

-
ChimerDB4STADTCGA-VQ-AA6D-01ABAZ2Achr12

57024560

-NACAchr12

57108471

-
ChimerDB4STADTCGA-VQ-AA6D-01ABAZ2Achr12

57024560

-NACAchr12

57118307

-
ChimerDB4STADTCGA-VQ-AA6D-01ABAZ2Achr12

57024560

-NACAchr12

57119124

-
ChimerDB4STADTCGA-VQ-AA6D-01ABAZ2Achr12

57024560

-NACAchr12

57119237

-


Top

Fusion Gene ORF analysis for BAZ2A-NACA

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000549884ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57108471

-
5UTR-3CDSENST00000549884ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57108471

-
5UTR-3CDSENST00000549884ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57108471

-
5UTR-3CDSENST00000549884ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57108471

-
5UTR-3CDSENST00000549884ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57108471

-
5UTR-5UTRENST00000549884ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57118307

-
5UTR-5UTRENST00000549884ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57119124

-
5UTR-5UTRENST00000549884ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57119237

-
5UTR-5UTRENST00000549884ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57118307

-
5UTR-5UTRENST00000549884ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57118307

-
5UTR-5UTRENST00000549884ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57119124

-
5UTR-5UTRENST00000549884ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57119237

-
5UTR-5UTRENST00000549884ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57108471

-
5UTR-5UTRENST00000549884ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57118307

-
5UTR-5UTRENST00000549884ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57119124

-
5UTR-5UTRENST00000549884ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57108471

-
5UTR-5UTRENST00000549884ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57118307

-
5UTR-5UTRENST00000549884ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57118307

-
5UTR-5UTRENST00000549884ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57108471

-
5UTR-5UTRENST00000549884ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57118307

-
5UTR-5UTRENST00000549884ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57118307

-
5UTR-intronENST00000549884ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57119124

-
5UTR-intronENST00000549884ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57119237

-
5UTR-intronENST00000549884ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57119237

-
5UTR-intronENST00000549884ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57119124

-
5UTR-intronENST00000549884ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57119237

-
5UTR-intronENST00000549884ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57119124

-
5UTR-intronENST00000549884ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57119237

-
5UTR-intronENST00000549884ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57119124

-
5UTR-intronENST00000549884ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57119237

-
5UTR-intronENST00000549884ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57119124

-
5UTR-intronENST00000549884ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-3CDSENST00000179765ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000179765ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000179765ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000179765ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000179765ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000179765ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000179765ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000179765ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000179765ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000179765ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000379441ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000379441ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000379441ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000379441ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000379441ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000379441ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000379441ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000379441ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000379441ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000379441ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000549884ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000549884ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000549884ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000549884ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000549884ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000551812ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000551812ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000551812ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000551812ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000551812ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000551812ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000551812ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000551812ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000551812ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000551812ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000553222ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000553222ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000553222ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000553222ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000553222ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000553222ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000553222ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000553222ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-3CDSENST00000553222ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-3CDSENST00000553222ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-5UTRENST00000179765ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000179765ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-5UTRENST00000179765ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-5UTRENST00000179765ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000179765ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-5UTRENST00000179765ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-5UTRENST00000179765ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000179765ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000179765ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000179765ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-5UTRENST00000179765ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-5UTRENST00000179765ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000179765ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-5UTRENST00000179765ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-5UTRENST00000179765ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-5UTRENST00000179765ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000179765ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-5UTRENST00000179765ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-5UTRENST00000179765ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000179765ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-5UTRENST00000179765ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-5UTRENST00000179765ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000179765ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-5UTRENST00000179765ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000179765ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000179765ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000179765ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-5UTRENST00000179765ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000179765ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-5UTRENST00000179765ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000179765ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000179765ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000379441ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000379441ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-5UTRENST00000379441ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-5UTRENST00000379441ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000379441ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-5UTRENST00000379441ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-5UTRENST00000379441ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000379441ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000379441ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000379441ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-5UTRENST00000379441ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-5UTRENST00000379441ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000379441ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-5UTRENST00000379441ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-5UTRENST00000379441ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-5UTRENST00000379441ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000379441ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-5UTRENST00000379441ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-5UTRENST00000379441ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000379441ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-5UTRENST00000379441ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-5UTRENST00000379441ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000379441ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-5UTRENST00000379441ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000379441ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000379441ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000379441ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-5UTRENST00000379441ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000379441ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-5UTRENST00000379441ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000379441ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000379441ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000549884ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000549884ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-5UTRENST00000549884ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-5UTRENST00000549884ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000549884ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000549884ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-5UTRENST00000549884ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-5UTRENST00000549884ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-5UTRENST00000549884ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000549884ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-5UTRENST00000549884ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-5UTRENST00000549884ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000549884ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000549884ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-5UTRENST00000549884ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000549884ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000551812ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000551812ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-5UTRENST00000551812ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-5UTRENST00000551812ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000551812ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-5UTRENST00000551812ENST00000356769BAZ2Achr12

57024560

-NACAchr12

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-
intron-5UTRENST00000551812ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000551812ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000551812ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000551812ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-5UTRENST00000551812ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-5UTRENST00000551812ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000551812ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-5UTRENST00000551812ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-5UTRENST00000551812ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-5UTRENST00000551812ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000551812ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-5UTRENST00000551812ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-5UTRENST00000551812ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000551812ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-5UTRENST00000551812ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-5UTRENST00000551812ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000551812ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-5UTRENST00000551812ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000551812ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000551812ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000551812ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-5UTRENST00000551812ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000551812ENST00000551793BAZ2Achr12

57024560

-NACAchr12

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-
intron-5UTRENST00000551812ENST00000551793BAZ2Achr12

57024560

-NACAchr12

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-
intron-5UTRENST00000551812ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000551812ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000553222ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000553222ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-5UTRENST00000553222ENST00000356769BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-5UTRENST00000553222ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000553222ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-5UTRENST00000553222ENST00000356769BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-5UTRENST00000553222ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000553222ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000553222ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000553222ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-5UTRENST00000553222ENST00000454682BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-5UTRENST00000553222ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000553222ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-5UTRENST00000553222ENST00000454682BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-5UTRENST00000553222ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-5UTRENST00000553222ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000553222ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-5UTRENST00000553222ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-5UTRENST00000553222ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000553222ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-5UTRENST00000553222ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-5UTRENST00000553222ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000553222ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-5UTRENST00000553222ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000553222ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000553222ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000553222ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57108471

-
intron-5UTRENST00000553222ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000553222ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57108471

-
intron-5UTRENST00000553222ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-5UTRENST00000553222ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57118307

-
intron-5UTRENST00000553222ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57118307

-
intron-intronENST00000179765ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000179765ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000179765ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000179765ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000179765ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000179765ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000179765ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000179765ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000179765ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000179765ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000179765ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000179765ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000179765ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000179765ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000179765ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000179765ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000179765ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000179765ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000179765ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000179765ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000179765ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000179765ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000379441ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000379441ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000379441ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000379441ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000379441ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000379441ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000379441ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000379441ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000379441ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000379441ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000379441ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000379441ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000379441ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000379441ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000379441ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000379441ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000379441ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000379441ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000379441ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000379441ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000379441ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000379441ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000549884ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000549884ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000549884ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000549884ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000549884ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000549884ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000549884ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000549884ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000549884ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000549884ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000549884ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000551812ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000551812ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000551812ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000551812ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000551812ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000551812ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000551812ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000551812ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000551812ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000551812ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000551812ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000551812ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000551812ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000551812ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000551812ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000551812ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000551812ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000551812ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000551812ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000551812ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000551812ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000551812ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000553222ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000553222ENST00000393891BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000553222ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000553222ENST00000393891BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000553222ENST00000546392BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000553222ENST00000546392BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000553222ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000553222ENST00000548563BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000553222ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000553222ENST00000548563BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000553222ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000553222ENST00000550952BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000553222ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000553222ENST00000550952BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000553222ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000553222ENST00000551793BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000553222ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000553222ENST00000551793BAZ2Achr12

57024560

-NACAchr12

57119237

-
intron-intronENST00000553222ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57119124

-
intron-intronENST00000553222ENST00000552540BAZ2Achr12

57023909

-NACAchr12

57119237

-
intron-intronENST00000553222ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57119124

-
intron-intronENST00000553222ENST00000552540BAZ2Achr12

57024560

-NACAchr12

57119237

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

Top

Fusion Genomic Features for BAZ2A-NACA


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)


Top

Fusion Protein Features for BAZ2A-NACA


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:57024560/:57118307)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.NACA

E9PAV3

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Cardiac- and muscle-specific transcription factor. May act to regulate the expression of genes involved in the development of myotubes. Plays a critical role in ventricular cardiomyocyte expansion and regulates postnatal skeletal muscle growth and regeneration. Involved in the organized assembly of thick and thin filaments of myofibril sarcomeres (By similarity). {ECO:0000250|UniProtKB:P70670}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for BAZ2A-NACA


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for BAZ2A-NACA


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BAZ2A-NACA


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BAZ2A-NACA


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneBAZ2AC0033578Prostatic Neoplasms1CTD_human
HgeneBAZ2AC0376358Malignant neoplasm of prostate1CTD_human
TgeneC0004238Atrial Fibrillation2CTD_human
TgeneC0235480Paroxysmal atrial fibrillation2CTD_human
TgeneC2585653Persistent atrial fibrillation2CTD_human
TgeneC3468561familial atrial fibrillation2CTD_human