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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ARAP1-FADD (FusionGDB2 ID:HG116985TG8772)

Fusion Gene Summary for ARAP1-FADD

check button Fusion gene summary
Fusion gene informationFusion gene name: ARAP1-FADD
Fusion gene ID: hg116985tg8772
HgeneTgene
Gene symbol

ARAP1

FADD

Gene ID

116985

8772

Gene nameArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1Fas associated via death domain
SynonymsCENTD2GIG3|MORT1
Cytomap('ARAP1')('FADD')

11q13.4

11q13.3

Type of geneprotein-codingprotein-coding
Descriptionarf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1centaurin-delta-2cnt-d2FAS-associated death domain proteinFas (TNFRSF6)-associated via death domainFas-associating death domain-containing proteinFas-associating protein with death domaingrowth-inhibiting gene 3 proteinmediator of receptor-induced toxicity
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000393609, ENST00000334211, 
ENST00000359373, ENST00000393605, 
ENST00000426523, ENST00000429686, 
ENST00000455638, ENST00000495878, 
Fusion gene scores* DoF score15 X 15 X 9=20255 X 2 X 4=40
# samples 176
** MAII scorelog2(17/2025*10)=-3.57431525652165
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/40*10)=0.584962500721156
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: ARAP1 [Title/Abstract] AND FADD [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointARAP1(72412694)-FADD(70052239), # samples:3
Anticipated loss of major functional domain due to fusion event.ARAP1-FADD seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARAP1-FADD seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARAP1-FADD seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ARAP1-FADD seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ARAP1-FADD seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ARAP1-FADD seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneARAP1

GO:0043547

positive regulation of GTPase activity

11804590

TgeneFADD

GO:0032757

positive regulation of interleukin-8 production

16127453

TgeneFADD

GO:0032760

positive regulation of tumor necrosis factor production

16127453

TgeneFADD

GO:0036462

TRAIL-activated apoptotic signaling pathway

21785459

TgeneFADD

GO:0043065

positive regulation of apoptotic process

11821383

TgeneFADD

GO:0045862

positive regulation of proteolysis

18387192

TgeneFADD

GO:0045944

positive regulation of transcription by RNA polymerase II

16127453

TgeneFADD

GO:0097190

apoptotic signaling pathway

11101870

TgeneFADD

GO:0097191

extrinsic apoptotic signaling pathway

21785459

TgeneFADD

GO:0097202

activation of cysteine-type endopeptidase activity

18387192


check buttonFusion gene breakpoints across ARAP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across FADD (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-44-A4SU-01AARAP1chr11

72412694

-FADDchr11

70052239

+


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Fusion Gene ORF analysis for ARAP1-FADD

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000393609ENST00000301838ARAP1chr11

72412694

-FADDchr11

70052239

+
In-frameENST00000334211ENST00000301838ARAP1chr11

72412694

-FADDchr11

70052239

+
In-frameENST00000359373ENST00000301838ARAP1chr11

72412694

-FADDchr11

70052239

+
In-frameENST00000393605ENST00000301838ARAP1chr11

72412694

-FADDchr11

70052239

+
In-frameENST00000426523ENST00000301838ARAP1chr11

72412694

-FADDchr11

70052239

+
In-frameENST00000429686ENST00000301838ARAP1chr11

72412694

-FADDchr11

70052239

+
In-frameENST00000455638ENST00000301838ARAP1chr11

72412694

-FADDchr11

70052239

+
intron-3CDSENST00000495878ENST00000301838ARAP1chr11

72412694

-FADDchr11

70052239

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000359373ARAP1chr1172412694-ENST00000301838FADDchr1170052239+441231548103494894
ENST00000455638ARAP1chr1172412694-ENST00000301838FADDchr1170052239+3560230202642880
ENST00000393605ARAP1chr1172412694-ENST00000301838FADDchr1170052239+339621385442478644
ENST00000334211ARAP1chr1172412694-ENST00000301838FADDchr1170052239+356023025102642710
ENST00000426523ARAP1chr1172412694-ENST00000301838FADDchr1170052239+323019721802312710
ENST00000429686ARAP1chr1172412694-ENST00000301838FADDchr1170052239+304717891802129649

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000359373ENST00000301838ARAP1chr1172412694-FADDchr1170052239+0.0041113990.99588865
ENST00000455638ENST00000301838ARAP1chr1172412694-FADDchr1170052239+0.0054326470.9945674
ENST00000393605ENST00000301838ARAP1chr1172412694-FADDchr1170052239+0.0047976120.9952024
ENST00000334211ENST00000301838ARAP1chr1172412694-FADDchr1170052239+0.0032532450.9967468
ENST00000426523ENST00000301838ARAP1chr1172412694-FADDchr1170052239+0.0054144980.9945856
ENST00000429686ENST00000301838ARAP1chr1172412694-FADDchr1170052239+0.0061609080.9938391

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Fusion Genomic Features for ARAP1-FADD


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ARAP1chr1172412693-FADDchr1170052238+0.0001969170.9998031
ARAP1chr1172412693-FADDchr1170052238+0.0001969170.9998031

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ARAP1-FADD


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:72412694/chr11:70052239)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARAP1chr11:72412694chr11:70052239ENST00000334211-1433327_4195221206.0DomainPH 1
HgeneARAP1chr11:72412694chr11:70052239ENST00000334211-14336_705221206.0DomainSAM
HgeneARAP1chr11:72412694chr11:70052239ENST00000359373-1634327_4197671440.0DomainPH 1
HgeneARAP1chr11:72412694chr11:70052239ENST00000359373-1634440_5297671440.0DomainPH 2
HgeneARAP1chr11:72412694chr11:70052239ENST00000359373-1634535_6607671440.0DomainArf-GAP
HgeneARAP1chr11:72412694chr11:70052239ENST00000359373-16346_707671440.0DomainSAM
HgeneARAP1chr11:72412694chr11:70052239ENST00000393605-1130327_4195271211.0DomainPH 1
HgeneARAP1chr11:72412694chr11:70052239ENST00000393605-1130440_5295271211.0DomainPH 2
HgeneARAP1chr11:72412694chr11:70052239ENST00000393605-11306_705271211.0DomainSAM
HgeneARAP1chr11:72412694chr11:70052239ENST00000393609-1635327_4197671451.0DomainPH 1
HgeneARAP1chr11:72412694chr11:70052239ENST00000393609-1635440_5297671451.0DomainPH 2
HgeneARAP1chr11:72412694chr11:70052239ENST00000393609-1635535_6607671451.0DomainArf-GAP
HgeneARAP1chr11:72412694chr11:70052239ENST00000393609-16356_707671451.0DomainSAM
HgeneARAP1chr11:72412694chr11:70052239ENST00000429686-1331327_4194611134.0DomainPH 1
HgeneARAP1chr11:72412694chr11:70052239ENST00000429686-13316_704611134.0DomainSAM
HgeneARAP1chr11:72412694chr11:70052239ENST00000455638-1432327_4197671440.0DomainPH 1
HgeneARAP1chr11:72412694chr11:70052239ENST00000455638-1432440_5297671440.0DomainPH 2
HgeneARAP1chr11:72412694chr11:70052239ENST00000455638-1432535_6607671440.0DomainArf-GAP
HgeneARAP1chr11:72412694chr11:70052239ENST00000455638-14326_707671440.0DomainSAM
HgeneARAP1chr11:72412694chr11:70052239ENST00000359373-1634550_5767671440.0Zinc fingerC4-type
HgeneARAP1chr11:72412694chr11:70052239ENST00000393609-1635550_5767671451.0Zinc fingerC4-type
HgeneARAP1chr11:72412694chr11:70052239ENST00000455638-1432550_5767671440.0Zinc fingerC4-type
TgeneFADDchr11:72412694chr11:70052239ENST000003018380297_18195209.0DomainDeath

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARAP1chr11:72412694chr11:70052239ENST00000334211-14331172_12615221206.0DomainRas-associating
HgeneARAP1chr11:72412694chr11:70052239ENST00000334211-14331274_13965221206.0DomainPH 4
HgeneARAP1chr11:72412694chr11:70052239ENST00000334211-1433440_5295221206.0DomainPH 2
HgeneARAP1chr11:72412694chr11:70052239ENST00000334211-1433535_6605221206.0DomainArf-GAP
HgeneARAP1chr11:72412694chr11:70052239ENST00000334211-1433743_8505221206.0DomainPH 3
HgeneARAP1chr11:72412694chr11:70052239ENST00000334211-1433954_11395221206.0DomainRho-GAP
HgeneARAP1chr11:72412694chr11:70052239ENST00000359373-16341172_12617671440.0DomainRas-associating
HgeneARAP1chr11:72412694chr11:70052239ENST00000359373-16341274_13967671440.0DomainPH 4
HgeneARAP1chr11:72412694chr11:70052239ENST00000359373-1634743_8507671440.0DomainPH 3
HgeneARAP1chr11:72412694chr11:70052239ENST00000359373-1634954_11397671440.0DomainRho-GAP
HgeneARAP1chr11:72412694chr11:70052239ENST00000393605-11301172_12615271211.0DomainRas-associating
HgeneARAP1chr11:72412694chr11:70052239ENST00000393605-11301274_13965271211.0DomainPH 4
HgeneARAP1chr11:72412694chr11:70052239ENST00000393605-1130535_6605271211.0DomainArf-GAP
HgeneARAP1chr11:72412694chr11:70052239ENST00000393605-1130743_8505271211.0DomainPH 3
HgeneARAP1chr11:72412694chr11:70052239ENST00000393605-1130954_11395271211.0DomainRho-GAP
HgeneARAP1chr11:72412694chr11:70052239ENST00000393609-16351172_12617671451.0DomainRas-associating
HgeneARAP1chr11:72412694chr11:70052239ENST00000393609-16351274_13967671451.0DomainPH 4
HgeneARAP1chr11:72412694chr11:70052239ENST00000393609-1635743_8507671451.0DomainPH 3
HgeneARAP1chr11:72412694chr11:70052239ENST00000393609-1635954_11397671451.0DomainRho-GAP
HgeneARAP1chr11:72412694chr11:70052239ENST00000429686-13311172_12614611134.0DomainRas-associating
HgeneARAP1chr11:72412694chr11:70052239ENST00000429686-13311274_13964611134.0DomainPH 4
HgeneARAP1chr11:72412694chr11:70052239ENST00000429686-1331440_5294611134.0DomainPH 2
HgeneARAP1chr11:72412694chr11:70052239ENST00000429686-1331535_6604611134.0DomainArf-GAP
HgeneARAP1chr11:72412694chr11:70052239ENST00000429686-1331743_8504611134.0DomainPH 3
HgeneARAP1chr11:72412694chr11:70052239ENST00000429686-1331954_11394611134.0DomainRho-GAP
HgeneARAP1chr11:72412694chr11:70052239ENST00000455638-14321172_12617671440.0DomainRas-associating
HgeneARAP1chr11:72412694chr11:70052239ENST00000455638-14321274_13967671440.0DomainPH 4
HgeneARAP1chr11:72412694chr11:70052239ENST00000455638-1432743_8507671440.0DomainPH 3
HgeneARAP1chr11:72412694chr11:70052239ENST00000455638-1432954_11397671440.0DomainRho-GAP
HgeneARAP1chr11:72412694chr11:70052239ENST00000334211-1433550_5765221206.0Zinc fingerC4-type
HgeneARAP1chr11:72412694chr11:70052239ENST00000393605-1130550_5765271211.0Zinc fingerC4-type
HgeneARAP1chr11:72412694chr11:70052239ENST00000429686-1331550_5764611134.0Zinc fingerC4-type
TgeneFADDchr11:72412694chr11:70052239ENST00000301838023_8195209.0DomainDED


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Fusion Gene Sequence for ARAP1-FADD


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>5757_5757_1_ARAP1-FADD_ARAP1_chr11_72412694_ENST00000334211_FADD_chr11_70052239_ENST00000301838_length(transcript)=3560nt_BP=2302nt
ACTTTTCGCTTTCTCAGTGTTTTCAGGAAGTGTGTGTGTTGGCCACGGCTGCAGGAGGTGGGGGAGACACAAAGCAGGAAGCCTCCGGGA
GACCAGAGCTGGGTGCAGACATACACACACACATACACACAGACACACAGAGTCACACACACTCACACACACTCTCTCTCTCTCTCCCTC
TGTCTTTCTCTCTCTCTCTCTCTCTCTGTCCTTTCCTCCTGGACAGATCCACAGTTATACACAGAAACAAACACACACGCACGTAGAGAA
GTGATTCACAAACACTTAAAGACATAAATCACAGGTGCAAAGCCATACCTGGGCTCAAAAACCTCCAAGAGAACGCAGCCTCAGACCCAC
CCAGGGGCCAGGGGCCAGGCTGTTTGCGAGACCAGCCCAGGCGGGACCCAGGCTTGCACGGGCAGGTACACGACATTCTTGGGCATACGC
AGCCCGCCTGGCCGGAGCTGTGGGAGTCCTCAGCCCCAAGACCCAGCAGGCGTCTGAGGCCTGCCCACTAAGGAGGAGGAGTCATTGCTG
CCATCATTATCATCCCCTCCCCAGCCACAGTCTGAGGAGCCCCTGTCCACCCTCCCCCAGGGGCCTCCCCAGCCTCCCTCTCCACCTCCC
TGCCCCCCGGAGATACCTCCAAAGCCGGTACGCCTGTTCCCAGAGTTCGATGACTCTGACTACGATGAGGTCCCAGAGGAGGGGCCGGGG
GCCCCAGCCAGAGTGATGACCAAGAAGGAGGAGCCCCCACCGAGCCGAGTCCCACGGGCCGTGCGCGTGGCCAGTCTGCTGAGCGAGGGA
GAGGAACTGTCTGGGGACGACCAAGGGGATGAGGAAGAGGATGACCACGCCTATGAGGGCGTCCCCAATGGCGGATGGCATACCAGCAGC
CTGAGCTTGTCCTTGCCCAGCACAATAGCTGCGCCACACCCCATGGACGGGCCGCCTGGGGGCTCCACCCCCGTCACACCAGTCATCAAG
GCTGGCTGGCTGGACAAGAACCCACCGCAGGGATCTTACATCTATCAGAAACGATGGGTGAGACTGGATACTGATCACCTGCGATACTTT
GACAGTAACAAGGACGCTTACTCTAAGCGCTTTATCTCTGTGGCCTGCATCTCCCACGTGGCTGCCATCGGGGACCAGAAGTTTGAAGTG
ATCACAAACAACCGAACCTTTGCCTTCCGGGCAGAGAGTGATGTGGAGCGGAAGGAGTGGATGCAGGCCCTGCAGCAGGCCATGGCTGAG
CAGCGTGCCCGGGCCCGGCTCTCTAGCGCTTATCTGCTGGGAGTTCCAGGCTCAGAGCAGCCTGACCGCGCTGGCAGCCTGGAGCTTCGT
GGCTTCAAGAATAAGCTGTACGTGGCCGTGGTCGGGGACAAAGTGCAGCTCTACAAGAATCTAGAGGAGTACCACCTGGGCATTGGCATC
ACCTTCATCGACATGAGCGTGGGCAACGTGAAGGAAGTGGACCGGCGCAGCTTCGACCTCACCACGCCCTACCGCATCTTCAGCTTCTCT
GCTGACTCAGAGCTAGAGAAGGAGCAGTGGTTGGAGGCCATGCAGGGAGCCATCGCTGAGGCCCTGTCTACCTCGGAGGTGGCCGAGCGC
ATCTGGGCTGCAGCCCCCAACAGGTTCTGTGCTGACTGCGGGGCTCCTCAGCCTGACTGGGCCTCCATCAACCTCTGTGTTGTTATCTGC
AAGCGCTGTGCAGGGGAGCACCGTGGCCTGGGCGCTGGCGTCTCCAAGGTGCGGAGCCTGAAGATGGACAGGAAGGTGTGGACAGAAACA
CTTATCGAGCTCTTCTTACAGCTGGGGAATGGCGCTGGGAACCGCTTCTGGGCAGCCAACGTGCCCCCCAGTGAGGCCCTGCAGCCCAGC
AGCAGCCCCAGCACCCGGCGGTGCCACCTGGAGGCCAAGTACCGTGAGGGCAAGTACCGCCGCTACCACCCGCTCTTTGGCAACCAGGAG
GAGCTGGACAAGGCCCTGTGTGCTGCAGTCACCACCACAGACCTGGCTGAGACCCAGGCGCTCCTGGGCTGTGGGGCTGGGATCAACTGC
TTCTCGGGGGACCCTGAGGCCCCCACGCCCCTGGCTCTTGCAGAGCAGGCGGGGCAGACGCTGCAGATGGAATTCCTTCGGAACAACCGG
ACCACAGAGGTGCCTCGGCTGGACTCGATGAAGCCCCTGGAAAAGCACTACTCAGTTGTCCTGCCGACCGTGAGCCACAGTGGCTTCCTC
TACAAGACTGCCTCTGCCGGCAAGCTGCTACAGGACCGCCGGGCCCGGGAAGACCTGTGTGCAGCATTTAACGTCATATGTGATAATGTG
GGGAAAGATTGGAGAAGGCTGGCTCGTCAGCTCAAAGTCTCAGACACCAAGATCGACAGCATCGAGGACAGATACCCCCGCAACCTGACA
GAGCGTGTGCGGGAGTCACTGAGAATCTGGAAGAACACAGAGAAGGAGAACGCAACAGTGGCCCACCTGGTGGGGGCTCTCAGGTCCTGC
CAGATGAACCTGGTGGCTGACCTGGTACAAGAGGTTCAGCAGGCCCGTGACCTCCAGAACAGGAGTGGGGCCATGTCCCCGATGTCATGG
AACTCAGACGCATCTACCTCCGAAGCGTCCTGATGGGCCGCTGCTTTGCGCTGGTGGACCACAGGCATCTACACAGCCTGGACTTTGGTT
CTCTCCAGGAAGGTAGCCCAGCACTGTGAAGACCCAGCAGGAAGCCAGGCTGAGTGAGCCACAGACCACCTGCTTCTGAACTCAAGCTGC
GTTTATTAATGCCTCTCCCGCACCAGGCCGGGCTTGGGCCCTGCACAGATATTTCCATTTCTTCCTCACTATGACACTGAGCAAGATCTT
GTCTCCACTAAATGAGCTCCTGCGGGAGTAGTTGGAAAGTTGGAACCGTGTCCAGCACAGAAGGAATCTGTGCAGATGAGCAGTCACACT
GTTACTCCACAGCGGAGGAGACCAGCTCAGAGGCCCAGGAATCGGAGCGAAGCAGAGAGGTGGAGAACTGGGATTTGAACCCCCGCCATC
CTTCACCAGAGCCCATGCTCAACCACTGTGGCGTTCTGCTGCCCCTGCAGTTGGCAGAAAGGATGTTTTGTCCCATTTCCTTGGAGGCCA
CCGGGACAGACCTGGACACTAGGGTCAGGCGGGGTGCTGTGGTGGGGAGAGGCATGGCTGGGGTGGGGGTGGGGAGACCTGGTTGGCCGT
GGTCCAGCTCTTGGCCCCTGTGTGAGTTGAGTCTCCTCTCTGAGACTGCTAAGTAGGGGCAGTGATGGTTGCCAGGACGAATTGAGATAA
TATCTGTGAGGTGCTGATGAGTGATTGACACACAGCACTCTCTAAATCTTCCTTGTGAGGATTATGGGTCCTGCAATTCTACAGTTTCTT
ACTGTTTTGTATCAAAATCACTATCTTTCTGATAACAGAATTGCCAAGGCAGCGGGATCTCGTATCTTTAAAAAGCAGTCCTCTTATTCC

>5757_5757_1_ARAP1-FADD_ARAP1_chr11_72412694_ENST00000334211_FADD_chr11_70052239_ENST00000301838_length(amino acids)=710AA_BP=597
MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA
VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV
RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ
PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE
ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN
VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT
LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDS

--------------------------------------------------------------
>5757_5757_2_ARAP1-FADD_ARAP1_chr11_72412694_ENST00000359373_FADD_chr11_70052239_ENST00000301838_length(transcript)=4412nt_BP=3154nt
GATTCACAAGGAATGACCCTCTTCATCGCCTCTCCTAATTCAGTCCTCACAACAGTCCTTTTACAAATGGGACAACAGGTTAGAGGAAGT
CAGGCAGATTTCCAGCATCATAGAGAGTAAAGGACCAGGGAAGGATCAGGATTCAAGGACTGCACCCAGGCTCTGCTTCCAGCTTGCTGT
GTGACTTTGGGTAATTTTGTTCCCTTAGGGAACTGAGCTTTCTCATTTGTAAATGCAAACAGGCTGTTGGGAGGATCAAATGAGATCCAG
GGGTGAAAACAGCTTAGTTTACTTTCAGGAATTTACCCACGCGGTATATAAAGGCAAAATATTATTATAGTCAGGTGATTGTAGATTGAG
GAACCCATTTCCTCATTCTGCAAATTGCAAACCTGAGGGCCCAAAGAGGGACAGGGGCTTGCCCCAGGTCTCAGCAGGCTGTGAGCAAGA
GCTAAAGCCTAATCCTCCTGCCTTTGGGCCTGGAGCCCTTCCTTGTACCCCAGGGGTCAGTGTCTTTGTTGGATACAGGCTTAGATTGAC
TGACTGTACCCTGAGAACCTAGGGGAGTCCCTGTTCCCAATTCTTCTCCTACCCCCACCTTGGCCTGATGGAGGAAGACCCTGCTGTGTT
GAGATGAGCACCAGAGCCAAGAAGCTGAGGAGGATCTGGAGAATTCTGGAGGAAGAGGAGAGTGTTGCTGGAGCTGTACAGACCCTGCTT
CTCAGCTCCCGCCTCAGGCCGAGATGAGGAGCCCTTCAGAATAGCTGCTGTCTCTGGGAGGACCCGGGCGTCCTTGGCAGCCCAGCTGCT
CTGGACAAAGCCCTGCCAGTCAGGCCTCCGCTGGCAGGAACCATGGCAGAGGCTGGGGATGCTGCGCTATCGGTGGCCGAGTGGCTGCGG
GCATTGCACCTGGAGCAGTACACGGGGCTCTTTGAGCAGCATGGCCTGGTGTGGGCCACTGAGTGCCAAGGCCTCAGCGACACCCGCCTG
ATGGACATGGGCATGCTACTCCCTGGTCACCGCCGCCGCATCCTGGCTGGCCTGCTCCGTGCCCATACCTCACCGGCCCCTGCACCCCGC
CCCACCCCACGGCCTGTGCCCATGAAGCGCCACATCTTCCGCTCACCACCTGTGCCTGCCACTCCACCCGAGCCGCTGCCCACCACTACA
GAGGATGAGGGGCTCCCCGCTGCCCCACCCATCCCGCCCCGGAGGAGCTGCCTTCCGCCCACCTGCTTCACCACCCCATCCACAGCTGCC
CCAGACCCTGTGCTGCCCCCGCTGCCTGCTAAGCGGCATTTGGCAGAGCTGAGCGTTCCACCCGTGCCGCCCCGCACCGGACCCCCCCGC
CTGCTGGTGAGCCTGCCCACTAAGGAGGAGGAGTCATTGCTGCCATCATTATCATCCCCTCCCCAGCCACAGTCTGAGGAGCCCCTGTCC
ACCCTCCCCCAGGGGCCTCCCCAGCCTCCCTCTCCACCTCCCTGCCCCCCGGAGATACCTCCAAAGCCGGTACGCCTGTTCCCAGAGTTC
GATGACTCTGACTACGATGAGGTCCCAGAGGAGGGGCCGGGGGCCCCAGCCAGAGTGATGACCAAGAAGGAGGAGCCCCCACCGAGCCGA
GTCCCACGGGCCGTGCGCGTGGCCAGTCTGCTGAGCGAGGGAGAGGAACTGTCTGGGGACGACCAAGGGGATGAGGAAGAGGATGACCAC
GCCTATGAGGGCGTCCCCAATGGCGGATGGCATACCAGCAGCCTGAGCTTGTCCTTGCCCAGCACAATAGCTGCGCCACACCCCATGGAC
GGGCCGCCTGGGGGCTCCACCCCCGTCACACCAGTCATCAAGGCTGGCTGGCTGGACAAGAACCCACCGCAGGGATCTTACATCTATCAG
AAACGATGGGTGAGACTGGATACTGATCACCTGCGATACTTTGACAGTAACAAGGACGCTTACTCTAAGCGCTTTATCTCTGTGGCCTGC
ATCTCCCACGTGGCTGCCATCGGGGACCAGAAGTTTGAAGTGATCACAAACAACCGAACCTTTGCCTTCCGGGCAGAGAGTGATGTGGAG
CGGAAGGAGTGGATGCAGGCCCTGCAGCAGGCCATGGCTGAGCAGCGTGCCCGGGCCCGGCTCTCTAGCGCTTATCTGCTGGGAGTTCCA
GGCTCAGAGCAGCCTGACCGCGCTGGCAGCCTGGAGCTTCGTGGCTTCAAGAATAAGCTGTACGTGGCCGTGGTCGGGGACAAAGTGCAG
CTCTACAAGAATCTAGAGGAGTACCACCTGGGCATTGGCATCACCTTCATCGACATGAGCGTGGGCAACGTGAAGGAAGTGGACCGGCGC
AGCTTCGACCTCACCACGCCCTACCGCATCTTCAGCTTCTCTGCTGACTCAGAGCTAGAGAAGGAGCAGTGGTTGGAGGCCATGCAGGGA
GCCATCGCTGAGGCCCTGTCTACCTCGGAGGTGGCCGAGCGCATCTGGGCTGCAGCCCCCAACAGGTTCTGTGCTGACTGCGGGGCTCCT
CAGCCTGACTGGGCCTCCATCAACCTCTGTGTTGTTATCTGCAAGCGCTGTGCAGGGGAGCACCGTGGCCTGGGCGCTGGCGTCTCCAAG
GTGCGGAGCCTGAAGATGGACAGGAAGGTGTGGACAGAAACACTTATCGAGCTCTTCTTACAGCTGGGGAATGGCGCTGGGAACCGCTTC
TGGGCAGCCAACGTGCCCCCCAGTGAGGCCCTGCAGCCCAGCAGCAGCCCCAGCACCCGGCGGTGCCACCTGGAGGCCAAGTACCGTGAG
GGCAAGTACCGCCGCTACCACCCGCTCTTTGGCAACCAGGAGGAGCTGGACAAGGCCCTGTGTGCTGCAGTCACCACCACAGACCTGGCT
GAGACCCAGGCGCTCCTGGGCTGTGGGGCTGGGATCAACTGCTTCTCGGGGGACCCTGAGGCCCCCACGCCCCTGGCTCTTGCAGAGCAG
GCGGGGCAGACGCTGCAGATGGAATTCCTTCGGAACAACCGGACCACAGAGGTGCCTCGGCTGGACTCGATGAAGCCCCTGGAAAAGCAC
TACTCAGTTGTCCTGCCGACCGTGAGCCACAGTGGCTTCCTCTACAAGACTGCCTCTGCCGGCAAGCTGCTACAGGACCGCCGGGCCCGG
GAAGACCTGTGTGCAGCATTTAACGTCATATGTGATAATGTGGGGAAAGATTGGAGAAGGCTGGCTCGTCAGCTCAAAGTCTCAGACACC
AAGATCGACAGCATCGAGGACAGATACCCCCGCAACCTGACAGAGCGTGTGCGGGAGTCACTGAGAATCTGGAAGAACACAGAGAAGGAG
AACGCAACAGTGGCCCACCTGGTGGGGGCTCTCAGGTCCTGCCAGATGAACCTGGTGGCTGACCTGGTACAAGAGGTTCAGCAGGCCCGT
GACCTCCAGAACAGGAGTGGGGCCATGTCCCCGATGTCATGGAACTCAGACGCATCTACCTCCGAAGCGTCCTGATGGGCCGCTGCTTTG
CGCTGGTGGACCACAGGCATCTACACAGCCTGGACTTTGGTTCTCTCCAGGAAGGTAGCCCAGCACTGTGAAGACCCAGCAGGAAGCCAG
GCTGAGTGAGCCACAGACCACCTGCTTCTGAACTCAAGCTGCGTTTATTAATGCCTCTCCCGCACCAGGCCGGGCTTGGGCCCTGCACAG
ATATTTCCATTTCTTCCTCACTATGACACTGAGCAAGATCTTGTCTCCACTAAATGAGCTCCTGCGGGAGTAGTTGGAAAGTTGGAACCG
TGTCCAGCACAGAAGGAATCTGTGCAGATGAGCAGTCACACTGTTACTCCACAGCGGAGGAGACCAGCTCAGAGGCCCAGGAATCGGAGC
GAAGCAGAGAGGTGGAGAACTGGGATTTGAACCCCCGCCATCCTTCACCAGAGCCCATGCTCAACCACTGTGGCGTTCTGCTGCCCCTGC
AGTTGGCAGAAAGGATGTTTTGTCCCATTTCCTTGGAGGCCACCGGGACAGACCTGGACACTAGGGTCAGGCGGGGTGCTGTGGTGGGGA
GAGGCATGGCTGGGGTGGGGGTGGGGAGACCTGGTTGGCCGTGGTCCAGCTCTTGGCCCCTGTGTGAGTTGAGTCTCCTCTCTGAGACTG
CTAAGTAGGGGCAGTGATGGTTGCCAGGACGAATTGAGATAATATCTGTGAGGTGCTGATGAGTGATTGACACACAGCACTCTCTAAATC
TTCCTTGTGAGGATTATGGGTCCTGCAATTCTACAGTTTCTTACTGTTTTGTATCAAAATCACTATCTTTCTGATAACAGAATTGCCAAG
GCAGCGGGATCTCGTATCTTTAAAAAGCAGTCCTCTTATTCCTAAGGTAATCCTATTAAAACACAGCTTTACAACTTCCATACTACAAAA

>5757_5757_2_ARAP1-FADD_ARAP1_chr11_72412694_ENST00000359373_FADD_chr11_70052239_ENST00000301838_length(amino acids)=894AA_BP=781
MDKALPVRPPLAGTMAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPR
PTPRPVPMKRHIFRSPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPR
LLVSLPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSR
VPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQ
KRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVP
GSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQG
AIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRF
WAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQ
AGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREDLCAAFNVICDNVGKDWRRLARQLKVSDT

--------------------------------------------------------------
>5757_5757_3_ARAP1-FADD_ARAP1_chr11_72412694_ENST00000393605_FADD_chr11_70052239_ENST00000301838_length(transcript)=3396nt_BP=2138nt
GCCTGTCAGGGTGTTGTGGGGGTGCCCAGCTGCCTGTCAGACCCTGAGGACTACCAGACAGAGAGTGGGCAGCCATTTCCCGGGAGGCTT
CCCCTTCCCCCACCTCACTCTCTTGCCATACGGGGGTCAGGAGTCACGTGTAGCCACAGCGCTCTGGGCCAGGGGTCGGGGCTCTGGTGT
GGCTCCCCCAGGCCCTGGCTGTATGTGGGTGGGCATGTGGCCTCCCCCCACCCTGTGTGTTAGGAACTCGTGTCCTGTCCCGGAGTGTCT
GTCTCTGTTTCACTTCTTGTGTTCCCGTGTCTGTCTGTCTTGCATCCCTAGCCCGCAGTCTTTTTCTCTGTCCCTTTATCTTTCTGTTTT
TGTCTGTGTCCTAGGTCGGTTTCTGCCACTGGCTCTCCTGTCCCTGTGATCTGGGTCTCTGTGTGGTCTCCGCTGGCAGGGGGAGGGGAG
TGTGAGGAAACAGAACTAAAAGTGCTGGGCTGTGTGGGTCGGGGCTGTGTGGACAGAGGGGGCGTGGCAGCCCCGGGTGGGTGTGATCTG
TGGCTTGAAGGGAAGGATGACGCTGAGTGGGTCTCGGGGGCAGGAGGAGCCCCCACCGAGCCGAGTCCCACGGGCCGTGCGCGTGGCCAG
TCTGCTGAGCGAGGGAGAGGAACTGTCTGGGGACGACCAAGGGGATGAGGAAGAGGATGACCACGCCTATGAGGGCGTCCCCAATGGCGG
ATGGCATACCAGCAGCCTGAGCTTGTCCTTGCCCAGCACAATAGCTGCGCCACACCCCATGGACGGGCCGCCTGGGGGCTCCACCCCCGT
CACACCAGTCATCAAGGCTGGCTGGCTGGACAAGAACCCACCGCAGGGATCTTACATCTATCAGAAACGATGGGTGAGACTGGATACTGA
TCACCTGCGATACTTTGACAGTAACAAGGACGCTTACTCTAAGCGCTTTATCTCTGTGGCCTGCATCTCCCACGTGGCTGCCATCGGGGA
CCAGAAGTTTGAAGTGATCACAAACAACCGAACCTTTGCCTTCCGGGCAGAGAGTGATGTGGAGCGGAAGGAGTGGATGCAGGCCCTGCA
GCAGGCCATGGCTGAGCAGCGTGCCCGGGCCCGGCTCTCTAGCGCTTATCTGCTGGGAGTTCCAGGCTCAGAGCAGCCTGACCGCGCTGG
CAGCCTGGAGCTTCGTGGCTTCAAGAATAAGCTGTACGTGGCCGTGGTCGGGGACAAAGTGCAGCTCTACAAGAATCTAGAGGAGTACCA
CCTGGGCATTGGCATCACCTTCATCGACATGAGCGTGGGCAACGTGAAGGAAGTGGACCGGCGCAGCTTCGACCTCACCACGCCCTACCG
CATCTTCAGCTTCTCTGCTGACTCAGAGCTAGAGAAGGAGCAGTGGTTGGAGGCCATGCAGGGAGCCATCGCTGAGGCCCTGTCTACCTC
GGAGGTGGCCGAGCGCATCTGGGCTGCAGCCCCCAACAGGTTCTGTGCTGACTGCGGGGCTCCTCAGCCTGACTGGGCCTCCATCAACCT
CTGTGTTGTTATCTGCAAGCGCTGTGCAGGGGAGCACCGTGGCCTGGGCGCTGGCGTCTCCAAGGTGCGGAGCCTGAAGATGGACAGGAA
GGTGTGGACAGAAACACTTATCGAGCTCTTCTTACAGCTGGGGAATGGCGCTGGGAACCGCTTCTGGGCAGCCAACGTGCCCCCCAGTGA
GGCCCTGCAGCCCAGCAGCAGCCCCAGCACCCGGCGGTGCCACCTGGAGGCCAAGTACCGTGAGGGCAAGTACCGCCGCTACCACCCGCT
CTTTGGCAACCAGGAGGAGCTGGACAAGGCCCTGTGTGCTGCAGTCACCACCACAGACCTGGCTGAGACCCAGGCGCTCCTGGGCTGTGG
GGCTGGGATCAACTGCTTCTCGGGGGACCCTGAGGCCCCCACGCCCCTGGCTCTTGCAGAGCAGGCGGGGCAGACGCTGCAGATGGAATT
CCTTCGGAACAACCGGACCACAGAGGTGCCTCGGCTGGACTCGATGAAGCCCCTGGAAAAGCACTACTCAGTTGTCCTGCCGACCGTGAG
CCACAGTGGCTTCCTCTACAAGACTGCCTCTGCCGGCAAGCTGCTACAGGACCGCCGGGCCCGGGAAGACCTGTGTGCAGCATTTAACGT
CATATGTGATAATGTGGGGAAAGATTGGAGAAGGCTGGCTCGTCAGCTCAAAGTCTCAGACACCAAGATCGACAGCATCGAGGACAGATA
CCCCCGCAACCTGACAGAGCGTGTGCGGGAGTCACTGAGAATCTGGAAGAACACAGAGAAGGAGAACGCAACAGTGGCCCACCTGGTGGG
GGCTCTCAGGTCCTGCCAGATGAACCTGGTGGCTGACCTGGTACAAGAGGTTCAGCAGGCCCGTGACCTCCAGAACAGGAGTGGGGCCAT
GTCCCCGATGTCATGGAACTCAGACGCATCTACCTCCGAAGCGTCCTGATGGGCCGCTGCTTTGCGCTGGTGGACCACAGGCATCTACAC
AGCCTGGACTTTGGTTCTCTCCAGGAAGGTAGCCCAGCACTGTGAAGACCCAGCAGGAAGCCAGGCTGAGTGAGCCACAGACCACCTGCT
TCTGAACTCAAGCTGCGTTTATTAATGCCTCTCCCGCACCAGGCCGGGCTTGGGCCCTGCACAGATATTTCCATTTCTTCCTCACTATGA
CACTGAGCAAGATCTTGTCTCCACTAAATGAGCTCCTGCGGGAGTAGTTGGAAAGTTGGAACCGTGTCCAGCACAGAAGGAATCTGTGCA
GATGAGCAGTCACACTGTTACTCCACAGCGGAGGAGACCAGCTCAGAGGCCCAGGAATCGGAGCGAAGCAGAGAGGTGGAGAACTGGGAT
TTGAACCCCCGCCATCCTTCACCAGAGCCCATGCTCAACCACTGTGGCGTTCTGCTGCCCCTGCAGTTGGCAGAAAGGATGTTTTGTCCC
ATTTCCTTGGAGGCCACCGGGACAGACCTGGACACTAGGGTCAGGCGGGGTGCTGTGGTGGGGAGAGGCATGGCTGGGGTGGGGGTGGGG
AGACCTGGTTGGCCGTGGTCCAGCTCTTGGCCCCTGTGTGAGTTGAGTCTCCTCTCTGAGACTGCTAAGTAGGGGCAGTGATGGTTGCCA
GGACGAATTGAGATAATATCTGTGAGGTGCTGATGAGTGATTGACACACAGCACTCTCTAAATCTTCCTTGTGAGGATTATGGGTCCTGC
AATTCTACAGTTTCTTACTGTTTTGTATCAAAATCACTATCTTTCTGATAACAGAATTGCCAAGGCAGCGGGATCTCGTATCTTTAAAAA

>5757_5757_3_ARAP1-FADD_ARAP1_chr11_72412694_ENST00000393605_FADD_chr11_70052239_ENST00000301838_length(amino acids)=644AA_BP=531
MKGRMTLSGSRGQEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVT
PVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQ
AMAEQRARARLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRI
FSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKV
WTETLIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGA
GINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREDLCAAFNVI
CDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEVQQARDLQNRSGAMS

--------------------------------------------------------------
>5757_5757_4_ARAP1-FADD_ARAP1_chr11_72412694_ENST00000426523_FADD_chr11_70052239_ENST00000301838_length(transcript)=3230nt_BP=1972nt
ACCTCCAAGAGAACGCAGCCTCAGACCCACCCAGGGGCCAGGGGCCAGGCTGTTTGCGAGACCAGCCCAGGCGGGACCCAGGCTTGCACG
GGCAGGTACACGACATTCTTGGGCATACGCAGCCCGCCTGGCCGGAGCTGTGGGAGTCCTCAGCCCCAAGACCCAGCAGGCGTCTGAGGC
CTGCCCACTAAGGAGGAGGAGTCATTGCTGCCATCATTATCATCCCCTCCCCAGCCACAGTCTGAGGAGCCCCTGTCCACCCTCCCCCAG
GGGCCTCCCCAGCCTCCCTCTCCACCTCCCTGCCCCCCGGAGATACCTCCAAAGCCGGTACGCCTGTTCCCAGAGTTCGATGACTCTGAC
TACGATGAGGTCCCAGAGGAGGGGCCGGGGGCCCCAGCCAGAGTGATGACCAAGAAGGAGGAGCCCCCACCGAGCCGAGTCCCACGGGCC
GTGCGCGTGGCCAGTCTGCTGAGCGAGGGAGAGGAACTGTCTGGGGACGACCAAGGGGATGAGGAAGAGGATGACCACGCCTATGAGGGC
GTCCCCAATGGCGGATGGCATACCAGCAGCCTGAGCTTGTCCTTGCCCAGCACAATAGCTGCGCCACACCCCATGGACGGGCCGCCTGGG
GGCTCCACCCCCGTCACACCAGTCATCAAGGCTGGCTGGCTGGACAAGAACCCACCGCAGGGATCTTACATCTATCAGAAACGATGGGTG
AGACTGGATACTGATCACCTGCGATACTTTGACAGTAACAAGGACGCTTACTCTAAGCGCTTTATCTCTGTGGCCTGCATCTCCCACGTG
GCTGCCATCGGGGACCAGAAGTTTGAAGTGATCACAAACAACCGAACCTTTGCCTTCCGGGCAGAGAGTGATGTGGAGCGGAAGGAGTGG
ATGCAGGCCCTGCAGCAGGCCATGGCTGAGCAGCGTGCCCGGGCCCGGCTCTCTAGCGCTTATCTGCTGGGAGTTCCAGGCTCAGAGCAG
CCTGACCGCGCTGGCAGCCTGGAGCTTCGTGGCTTCAAGAATAAGCTGTACGTGGCCGTGGTCGGGGACAAAGTGCAGCTCTACAAGAAT
CTAGAGGAGTACCACCTGGGCATTGGCATCACCTTCATCGACATGAGCGTGGGCAACGTGAAGGAAGTGGACCGGCGCAGCTTCGACCTC
ACCACGCCCTACCGCATCTTCAGCTTCTCTGCTGACTCAGAGCTAGAGAAGGAGCAGTGGTTGGAGGCCATGCAGGGAGCCATCGCTGAG
GCCCTGTCTACCTCGGAGGTGGCCGAGCGCATCTGGGCTGCAGCCCCCAACAGGTTCTGTGCTGACTGCGGGGCTCCTCAGCCTGACTGG
GCCTCCATCAACCTCTGTGTTGTTATCTGCAAGCGCTGTGCAGGGGAGCACCGTGGCCTGGGCGCTGGCGTCTCCAAGGTGCGGAGCCTG
AAGATGGACAGGAAGGTGTGGACAGAAACACTTATCGAGCTCTTCTTACAGCTGGGGAATGGCGCTGGGAACCGCTTCTGGGCAGCCAAC
GTGCCCCCCAGTGAGGCCCTGCAGCCCAGCAGCAGCCCCAGCACCCGGCGGTGCCACCTGGAGGCCAAGTACCGTGAGGGCAAGTACCGC
CGCTACCACCCGCTCTTTGGCAACCAGGAGGAGCTGGACAAGGCCCTGTGTGCTGCAGTCACCACCACAGACCTGGCTGAGACCCAGGCG
CTCCTGGGCTGTGGGGCTGGGATCAACTGCTTCTCGGGGGACCCTGAGGCCCCCACGCCCCTGGCTCTTGCAGAGCAGGCGGGGCAGACG
CTGCAGATGGAATTCCTTCGGAACAACCGGACCACAGAGGTGCCTCGGCTGGACTCGATGAAGCCCCTGGAAAAGCACTACTCAGTTGTC
CTGCCGACCGTGAGCCACAGTGGCTTCCTCTACAAGACTGCCTCTGCCGGCAAGCTGCTACAGGACCGCCGGGCCCGGGAAGACCTGTGT
GCAGCATTTAACGTCATATGTGATAATGTGGGGAAAGATTGGAGAAGGCTGGCTCGTCAGCTCAAAGTCTCAGACACCAAGATCGACAGC
ATCGAGGACAGATACCCCCGCAACCTGACAGAGCGTGTGCGGGAGTCACTGAGAATCTGGAAGAACACAGAGAAGGAGAACGCAACAGTG
GCCCACCTGGTGGGGGCTCTCAGGTCCTGCCAGATGAACCTGGTGGCTGACCTGGTACAAGAGGTTCAGCAGGCCCGTGACCTCCAGAAC
AGGAGTGGGGCCATGTCCCCGATGTCATGGAACTCAGACGCATCTACCTCCGAAGCGTCCTGATGGGCCGCTGCTTTGCGCTGGTGGACC
ACAGGCATCTACACAGCCTGGACTTTGGTTCTCTCCAGGAAGGTAGCCCAGCACTGTGAAGACCCAGCAGGAAGCCAGGCTGAGTGAGCC
ACAGACCACCTGCTTCTGAACTCAAGCTGCGTTTATTAATGCCTCTCCCGCACCAGGCCGGGCTTGGGCCCTGCACAGATATTTCCATTT
CTTCCTCACTATGACACTGAGCAAGATCTTGTCTCCACTAAATGAGCTCCTGCGGGAGTAGTTGGAAAGTTGGAACCGTGTCCAGCACAG
AAGGAATCTGTGCAGATGAGCAGTCACACTGTTACTCCACAGCGGAGGAGACCAGCTCAGAGGCCCAGGAATCGGAGCGAAGCAGAGAGG
TGGAGAACTGGGATTTGAACCCCCGCCATCCTTCACCAGAGCCCATGCTCAACCACTGTGGCGTTCTGCTGCCCCTGCAGTTGGCAGAAA
GGATGTTTTGTCCCATTTCCTTGGAGGCCACCGGGACAGACCTGGACACTAGGGTCAGGCGGGGTGCTGTGGTGGGGAGAGGCATGGCTG
GGGTGGGGGTGGGGAGACCTGGTTGGCCGTGGTCCAGCTCTTGGCCCCTGTGTGAGTTGAGTCTCCTCTCTGAGACTGCTAAGTAGGGGC
AGTGATGGTTGCCAGGACGAATTGAGATAATATCTGTGAGGTGCTGATGAGTGATTGACACACAGCACTCTCTAAATCTTCCTTGTGAGG
ATTATGGGTCCTGCAATTCTACAGTTTCTTACTGTTTTGTATCAAAATCACTATCTTTCTGATAACAGAATTGCCAAGGCAGCGGGATCT

>5757_5757_4_ARAP1-FADD_ARAP1_chr11_72412694_ENST00000426523_FADD_chr11_70052239_ENST00000301838_length(amino acids)=710AA_BP=597
MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA
VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV
RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ
PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE
ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN
VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT
LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDS

--------------------------------------------------------------
>5757_5757_5_ARAP1-FADD_ARAP1_chr11_72412694_ENST00000429686_FADD_chr11_70052239_ENST00000301838_length(transcript)=3047nt_BP=1789nt
ACCTCCAAGAGAACGCAGCCTCAGACCCACCCAGGGGCCAGGGGCCAGGCTGTTTGCGAGACCAGCCCAGGCGGGACCCAGGCTTGCACG
GGCAGGTACACGACATTCTTGGGCATACGCAGCCCGCCTGGCCGGAGCTGTGGGAGTCCTCAGCCCCAAGACCCAGCAGGCGTCTGAGGC
CTGCCCACTAAGGAGGAGGAGTCATTGCTGCCATCATTATCATCCCCTCCCCAGCCACAGTCTGAGGAGCCCCTGTCCACCCTCCCCCAG
GGGCCTCCCCAGCCTCCCTCTCCACCTCCCTGCCCCCCGGAGATACCTCCAAAGCCGGTACGCCTGTTCCCAGAGTTCGATGACTCTGAC
TACGATGAGGTCCCAGAGGAGGGGCCGGGGGCCCCAGCCAGAGTGATGACCAAGAAGGAGGAGCCCCCACCGAGCCGAGTCCCACGGGCC
GTGCGCGTGGCCAGTCTGCTGAGCGAGGGAGAGGAACTGTCTGGGGACGACCAAGGGGATGAGGAAGAGGATGACCACGCCTATGAGGGC
GTCCCCAATGGCGGATGGCATACCAGCAGCCTGAGCTTGTCCTTGCCCAGCACAATAGCTGCGCCACACCCCATGGACGGGCCGCCTGGG
GGCTCCACCCCCGTCACACCAGTCATCAAGGCTGGCTGGCTGGACAAGAACCCACCGCAGGGATCTTACATCTATCAGAAACGATGGGTG
AGACTGGATACTGATCACCTGCGATACTTTGACAGTAACAAGGACGCTTACTCTAAGCGCTTTATCTCTGTGGCCTGCATCTCCCACGTG
GCTGCCATCGGGGACCAGAAGTTTGAAGTGATCACAAACAACCGAACCTTTGCCTTCCGGGCAGAGAGTGATGTGGAGCGGAAGGAGTGG
ATGCAGGCCCTGCAGCAGGCCATGGCTGAGCAGCGTGCCCGGGCCCGGCTCTCTAGCGCTTATCTGCTGGGAGTTCCAGGCTCAGAGCAG
CCTGACCGCGCTGGCAGCCTGGAGCTTCGTGGCTTCAAGAATAAGCTGTACGTGGCCGTGGTCGGGGACAAAGTGCAGCTCTACAAGAAT
CTAGAGGAGTACCACCTGGGCATTGGCATCACCTTCATCGACATGAGCGTGGGCAACGTGAAGGAAGTGGACCGGCGCAGCTTCGACCTC
ACCACGCCCTACCGCATCTTCAGCTTCTCTGCTGACTCAGAGCTAGAGAAGGAGCAGTGGTTGGAGGCCATGCAGGGAGCCATCGCTGAG
GCCCTGTCTACCTCGGAGGTGGCCGAGCGCATCTGGGCTGCAGCCCCCAACAGGTTCTGTGCTGACTGCGGGGCTCCTCAGCCTGACTGG
GCCTCCATCAACCTCTGTGTTGTTATCTGCAAGCGCTGTGCAGGGGAGCACCGTGGCCTGGGCGCTGGCGTCTCCAAGGTGCGGAGCCTG
AAGATGGACAGGAAGGTGTGGACAGAAACACTTATCGAGGCCCTGTGTGCTGCAGTCACCACCACAGACCTGGCTGAGACCCAGGCGCTC
CTGGGCTGTGGGGCTGGGATCAACTGCTTCTCGGGGGACCCTGAGGCCCCCACGCCCCTGGCTCTTGCAGAGCAGGCGGGGCAGACGCTG
CAGATGGAATTCCTTCGGAACAACCGGACCACAGAGGTGCCTCGGCTGGACTCGATGAAGCCCCTGGAAAAGCACTACTCAGTTGTCCTG
CCGACCGTGAGCCACAGTGGCTTCCTCTACAAGACTGCCTCTGCCGGCAAGCTGCTACAGGACCGCCGGGCCCGGGAAGACCTGTGTGCA
GCATTTAACGTCATATGTGATAATGTGGGGAAAGATTGGAGAAGGCTGGCTCGTCAGCTCAAAGTCTCAGACACCAAGATCGACAGCATC
GAGGACAGATACCCCCGCAACCTGACAGAGCGTGTGCGGGAGTCACTGAGAATCTGGAAGAACACAGAGAAGGAGAACGCAACAGTGGCC
CACCTGGTGGGGGCTCTCAGGTCCTGCCAGATGAACCTGGTGGCTGACCTGGTACAAGAGGTTCAGCAGGCCCGTGACCTCCAGAACAGG
AGTGGGGCCATGTCCCCGATGTCATGGAACTCAGACGCATCTACCTCCGAAGCGTCCTGATGGGCCGCTGCTTTGCGCTGGTGGACCACA
GGCATCTACACAGCCTGGACTTTGGTTCTCTCCAGGAAGGTAGCCCAGCACTGTGAAGACCCAGCAGGAAGCCAGGCTGAGTGAGCCACA
GACCACCTGCTTCTGAACTCAAGCTGCGTTTATTAATGCCTCTCCCGCACCAGGCCGGGCTTGGGCCCTGCACAGATATTTCCATTTCTT
CCTCACTATGACACTGAGCAAGATCTTGTCTCCACTAAATGAGCTCCTGCGGGAGTAGTTGGAAAGTTGGAACCGTGTCCAGCACAGAAG
GAATCTGTGCAGATGAGCAGTCACACTGTTACTCCACAGCGGAGGAGACCAGCTCAGAGGCCCAGGAATCGGAGCGAAGCAGAGAGGTGG
AGAACTGGGATTTGAACCCCCGCCATCCTTCACCAGAGCCCATGCTCAACCACTGTGGCGTTCTGCTGCCCCTGCAGTTGGCAGAAAGGA
TGTTTTGTCCCATTTCCTTGGAGGCCACCGGGACAGACCTGGACACTAGGGTCAGGCGGGGTGCTGTGGTGGGGAGAGGCATGGCTGGGG
TGGGGGTGGGGAGACCTGGTTGGCCGTGGTCCAGCTCTTGGCCCCTGTGTGAGTTGAGTCTCCTCTCTGAGACTGCTAAGTAGGGGCAGT
GATGGTTGCCAGGACGAATTGAGATAATATCTGTGAGGTGCTGATGAGTGATTGACACACAGCACTCTCTAAATCTTCCTTGTGAGGATT
ATGGGTCCTGCAATTCTACAGTTTCTTACTGTTTTGTATCAAAATCACTATCTTTCTGATAACAGAATTGCCAAGGCAGCGGGATCTCGT

>5757_5757_5_ARAP1-FADD_ARAP1_chr11_72412694_ENST00000429686_FADD_chr11_70052239_ENST00000301838_length(amino acids)=649AA_BP=536
MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA
VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV
RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ
PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE
ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIEALCAAVTTTDLAETQAL
LGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREDLCA
AFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEVQQARDLQNR

--------------------------------------------------------------
>5757_5757_6_ARAP1-FADD_ARAP1_chr11_72412694_ENST00000455638_FADD_chr11_70052239_ENST00000301838_length(transcript)=3560nt_BP=2302nt
ATGGCAGAGGCTGGGGATGCTGCGCTATCGGTGGCCGAGTGGCTGCGGGCATTGCACCTGGAGCAGTACACGGGGCTCTTTGAGCAGCAT
GGCCTGGTGTGGGCCACTGAGTGCCAAGGCCTCAGCGACACCCGCCTGATGGACATGGGCATGCTACTCCCTGGTCACCGCCGCCGCATC
CTGGCTGGCCTGCTCCGTGCCCATACCTCACCGGCCCCTGCACCCCGCCCCACCCCACGGCCTGTGCCCATGAAGCGCCACATCTTCCGC
TCACCACCTGTGCCTGCCACTCCACCCGAGCCGCTGCCCACCACTACAGAGGATGAGGGGCTCCCCGCTGCCCCACCCATCCCGCCCCGG
AGGAGCTGCCTTCCGCCCACCTGCTTCACCACCCCATCCACAGCTGCCCCAGACCCTGTGCTGCCCCCGCTGCCTGCTAAGCGGCATTTG
GCAGAGCTGAGCGTTCCACCCGTGCCGCCCCGCACCGGACCCCCCCGCCTGCTGGTGAGCCTGCCCACTAAGGAGGAGGAGTCATTGCTG
CCATCATTATCATCCCCTCCCCAGCCACAGTCTGAGGAGCCCCTGTCCACCCTCCCCCAGGGGCCTCCCCAGCCTCCCTCTCCACCTCCC
TGCCCCCCGGAGATACCTCCAAAGCCGGTACGCCTGTTCCCAGAGTTCGATGACTCTGACTACGATGAGGTCCCAGAGGAGGGGCCGGGG
GCCCCAGCCAGAGTGATGACCAAGAAGGAGGAGCCCCCACCGAGCCGAGTCCCACGGGCCGTGCGCGTGGCCAGTCTGCTGAGCGAGGGA
GAGGAACTGTCTGGGGACGACCAAGGGGATGAGGAAGAGGATGACCACGCCTATGAGGGCGTCCCCAATGGCGGATGGCATACCAGCAGC
CTGAGCTTGTCCTTGCCCAGCACAATAGCTGCGCCACACCCCATGGACGGGCCGCCTGGGGGCTCCACCCCCGTCACACCAGTCATCAAG
GCTGGCTGGCTGGACAAGAACCCACCGCAGGGATCTTACATCTATCAGAAACGATGGGTGAGACTGGATACTGATCACCTGCGATACTTT
GACAGTAACAAGGACGCTTACTCTAAGCGCTTTATCTCTGTGGCCTGCATCTCCCACGTGGCTGCCATCGGGGACCAGAAGTTTGAAGTG
ATCACAAACAACCGAACCTTTGCCTTCCGGGCAGAGAGTGATGTGGAGCGGAAGGAGTGGATGCAGGCCCTGCAGCAGGCCATGGCTGAG
CAGCGTGCCCGGGCCCGGCTCTCTAGCGCTTATCTGCTGGGAGTTCCAGGCTCAGAGCAGCCTGACCGCGCTGGCAGCCTGGAGCTTCGT
GGCTTCAAGAATAAGCTGTACGTGGCCGTGGTCGGGGACAAAGTGCAGCTCTACAAGAATCTAGAGGAGTACCACCTGGGCATTGGCATC
ACCTTCATCGACATGAGCGTGGGCAACGTGAAGGAAGTGGACCGGCGCAGCTTCGACCTCACCACGCCCTACCGCATCTTCAGCTTCTCT
GCTGACTCAGAGCTAGAGAAGGAGCAGTGGTTGGAGGCCATGCAGGGAGCCATCGCTGAGGCCCTGTCTACCTCGGAGGTGGCCGAGCGC
ATCTGGGCTGCAGCCCCCAACAGGTTCTGTGCTGACTGCGGGGCTCCTCAGCCTGACTGGGCCTCCATCAACCTCTGTGTTGTTATCTGC
AAGCGCTGTGCAGGGGAGCACCGTGGCCTGGGCGCTGGCGTCTCCAAGGTGCGGAGCCTGAAGATGGACAGGAAGGTGTGGACAGAAACA
CTTATCGAGCTCTTCTTACAGCTGGGGAATGGCGCTGGGAACCGCTTCTGGGCAGCCAACGTGCCCCCCAGTGAGGCCCTGCAGCCCAGC
AGCAGCCCCAGCACCCGGCGGTGCCACCTGGAGGCCAAGTACCGTGAGGGCAAGTACCGCCGCTACCACCCGCTCTTTGGCAACCAGGAG
GAGCTGGACAAGGCCCTGTGTGCTGCAGTCACCACCACAGACCTGGCTGAGACCCAGGCGCTCCTGGGCTGTGGGGCTGGGATCAACTGC
TTCTCGGGGGACCCTGAGGCCCCCACGCCCCTGGCTCTTGCAGAGCAGGCGGGGCAGACGCTGCAGATGGAATTCCTTCGGAACAACCGG
ACCACAGAGGTGCCTCGGCTGGACTCGATGAAGCCCCTGGAAAAGCACTACTCAGTTGTCCTGCCGACCGTGAGCCACAGTGGCTTCCTC
TACAAGACTGCCTCTGCCGGCAAGCTGCTACAGGACCGCCGGGCCCGGGAAGACCTGTGTGCAGCATTTAACGTCATATGTGATAATGTG
GGGAAAGATTGGAGAAGGCTGGCTCGTCAGCTCAAAGTCTCAGACACCAAGATCGACAGCATCGAGGACAGATACCCCCGCAACCTGACA
GAGCGTGTGCGGGAGTCACTGAGAATCTGGAAGAACACAGAGAAGGAGAACGCAACAGTGGCCCACCTGGTGGGGGCTCTCAGGTCCTGC
CAGATGAACCTGGTGGCTGACCTGGTACAAGAGGTTCAGCAGGCCCGTGACCTCCAGAACAGGAGTGGGGCCATGTCCCCGATGTCATGG
AACTCAGACGCATCTACCTCCGAAGCGTCCTGATGGGCCGCTGCTTTGCGCTGGTGGACCACAGGCATCTACACAGCCTGGACTTTGGTT
CTCTCCAGGAAGGTAGCCCAGCACTGTGAAGACCCAGCAGGAAGCCAGGCTGAGTGAGCCACAGACCACCTGCTTCTGAACTCAAGCTGC
GTTTATTAATGCCTCTCCCGCACCAGGCCGGGCTTGGGCCCTGCACAGATATTTCCATTTCTTCCTCACTATGACACTGAGCAAGATCTT
GTCTCCACTAAATGAGCTCCTGCGGGAGTAGTTGGAAAGTTGGAACCGTGTCCAGCACAGAAGGAATCTGTGCAGATGAGCAGTCACACT
GTTACTCCACAGCGGAGGAGACCAGCTCAGAGGCCCAGGAATCGGAGCGAAGCAGAGAGGTGGAGAACTGGGATTTGAACCCCCGCCATC
CTTCACCAGAGCCCATGCTCAACCACTGTGGCGTTCTGCTGCCCCTGCAGTTGGCAGAAAGGATGTTTTGTCCCATTTCCTTGGAGGCCA
CCGGGACAGACCTGGACACTAGGGTCAGGCGGGGTGCTGTGGTGGGGAGAGGCATGGCTGGGGTGGGGGTGGGGAGACCTGGTTGGCCGT
GGTCCAGCTCTTGGCCCCTGTGTGAGTTGAGTCTCCTCTCTGAGACTGCTAAGTAGGGGCAGTGATGGTTGCCAGGACGAATTGAGATAA
TATCTGTGAGGTGCTGATGAGTGATTGACACACAGCACTCTCTAAATCTTCCTTGTGAGGATTATGGGTCCTGCAATTCTACAGTTTCTT
ACTGTTTTGTATCAAAATCACTATCTTTCTGATAACAGAATTGCCAAGGCAGCGGGATCTCGTATCTTTAAAAAGCAGTCCTCTTATTCC

>5757_5757_6_ARAP1-FADD_ARAP1_chr11_72412694_ENST00000455638_FADD_chr11_70052239_ENST00000301838_length(amino acids)=880AA_BP=767
MAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPRPTPRPVPMKRHIFR
SPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPRLLVSLPTKEEESLL
PSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRAVRVASLLSEG
EELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYF
DSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQPDRAGSLELR
GFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAER
IWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAANVPPSEALQPS
SSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNR
TTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLT

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Fusion Gene PPI Analysis for ARAP1-FADD


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ARAP1-FADD


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ARAP1-FADD


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC3151062INFECTIONS, RECURRENT, WITH ENCEPHALOPATHY, HEPATIC DYSFUNCTION, AND CARDIOVASCULAR MALFORMATIONS2CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC0018784Sensorineural Hearing Loss (disorder)1CTD_human
TgeneC0027627Neoplasm Metastasis1CTD_human
TgeneC0038368Stomatognathic Diseases1CTD_human
TgeneC0376634Craniofacial Abnormalities1CTD_human
TgeneC1691779Sensory hearing loss1CTD_human
TgeneC1704330Dental Diseases1CTD_human
TgeneC2750325Oculootodental syndrome1ORPHANET
TgeneC3279150Functional hyposplenism1GENOMICS_ENGLAND
TgeneC4049796Abnormality of cardiovascular system morphology1GENOMICS_ENGLAND
TgeneC4317009Diverticular Diseases1CTD_human
TgeneC4505353Diverticular Bleeding1CTD_human