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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:AGAP1-CIR1 (FusionGDB2 ID:HG116987TG9541)

Fusion Gene Summary for AGAP1-CIR1

check button Fusion gene summary
Fusion gene informationFusion gene name: AGAP1-CIR1
Fusion gene ID: hg116987tg9541
HgeneTgene
Gene symbol

AGAP1

CIR1

Gene ID

116987

9541

Gene nameArfGAP with GTPase domain, ankyrin repeat and PH domain 1corepressor interacting with RBPJ, CIR1
SynonymsAGAP-1|CENTG2|GGAP1|cnt-g2CIR
Cytomap('AGAP1')('CIR1')

2q37.2

2q31.1

Type of geneprotein-codingprotein-coding
Descriptionarf-GAP with GTPase, ANK repeat and PH domain-containing protein 1Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 1GTP-binding and GTPase-activating protein 1centaurin, gamma 2corepressor interacting with RBPJ 1CBF1 (RBPJ) interacting corepressor 1CBF1-interacting corepressorcorepressor interacting with RBPJ, 1recepin
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000304032, ENST00000336665, 
ENST00000409457, ENST00000409538, 
ENST00000428334, 
Fusion gene scores* DoF score49 X 18 X 17=1499411 X 6 X 4=264
# samples 489
** MAII scorelog2(48/14994*10)=-4.96520709119934
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/264*10)=-1.55254102302878
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AGAP1 [Title/Abstract] AND CIR1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAGAP1(236715975)-CIR1(175252507), # samples:4
Anticipated loss of major functional domain due to fusion event.AGAP1-CIR1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
AGAP1-CIR1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
AGAP1-CIR1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
AGAP1-CIR1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCIR1

GO:0000122

negative regulation of transcription by RNA polymerase II

9874765

TgeneCIR1

GO:0045892

negative regulation of transcription, DNA-templated

9874765


check buttonFusion gene breakpoints across AGAP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CIR1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4COADTCGA-AY-5543-01AAGAP1chr2

236715975

-CIR1chr2

175252507

-
ChimerDB4COADTCGA-AY-5543-01AAGAP1chr2

236715975

+CIR1chr2

175252507

-
ChimerDB4COADTCGA-AY-5543AGAP1chr2

236715975

+CIR1chr2

175252507

-


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Fusion Gene ORF analysis for AGAP1-CIR1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000304032ENST00000342016AGAP1chr2

236715975

+CIR1chr2

175252507

-
In-frameENST00000304032ENST00000362053AGAP1chr2

236715975

+CIR1chr2

175252507

-
In-frameENST00000336665ENST00000342016AGAP1chr2

236715975

+CIR1chr2

175252507

-
In-frameENST00000336665ENST00000362053AGAP1chr2

236715975

+CIR1chr2

175252507

-
In-frameENST00000409457ENST00000342016AGAP1chr2

236715975

+CIR1chr2

175252507

-
In-frameENST00000409457ENST00000362053AGAP1chr2

236715975

+CIR1chr2

175252507

-
In-frameENST00000409538ENST00000342016AGAP1chr2

236715975

+CIR1chr2

175252507

-
In-frameENST00000409538ENST00000362053AGAP1chr2

236715975

+CIR1chr2

175252507

-
In-frameENST00000428334ENST00000342016AGAP1chr2

236715975

+CIR1chr2

175252507

-
In-frameENST00000428334ENST00000362053AGAP1chr2

236715975

+CIR1chr2

175252507

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000336665AGAP1chr2236715975+ENST00000342016CIR1chr2175252507-338616304212910829
ENST00000336665AGAP1chr2236715975+ENST00000362053CIR1chr2175252507-328416304212166581
ENST00000304032AGAP1chr2236715975+ENST00000342016CIR1chr2175252507-338616304212910829
ENST00000304032AGAP1chr2236715975+ENST00000362053CIR1chr2175252507-328416304212166581
ENST00000409538AGAP1chr2236715975+ENST00000342016CIR1chr2175252507-4097234141836211067
ENST00000409538AGAP1chr2236715975+ENST00000362053CIR1chr2175252507-399523414182877819
ENST00000428334AGAP1chr2236715975+ENST00000342016CIR1chr2175252507-2344588211868615
ENST00000428334AGAP1chr2236715975+ENST00000362053CIR1chr2175252507-2242588211124367
ENST00000409457AGAP1chr2236715975+ENST00000342016CIR1chr2175252507-340416484392928829
ENST00000409457AGAP1chr2236715975+ENST00000362053CIR1chr2175252507-330216484392184581

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000336665ENST00000342016AGAP1chr2236715975+CIR1chr2175252507-0.0006418770.9993581
ENST00000336665ENST00000362053AGAP1chr2236715975+CIR1chr2175252507-0.0012344630.9987656
ENST00000304032ENST00000342016AGAP1chr2236715975+CIR1chr2175252507-0.0006418770.9993581
ENST00000304032ENST00000362053AGAP1chr2236715975+CIR1chr2175252507-0.0012344630.9987656
ENST00000409538ENST00000342016AGAP1chr2236715975+CIR1chr2175252507-0.0014929720.99850696
ENST00000409538ENST00000362053AGAP1chr2236715975+CIR1chr2175252507-0.0016071860.99839276
ENST00000428334ENST00000342016AGAP1chr2236715975+CIR1chr2175252507-0.0029849420.9970151
ENST00000428334ENST00000362053AGAP1chr2236715975+CIR1chr2175252507-0.0025581740.99744177
ENST00000409457ENST00000342016AGAP1chr2236715975+CIR1chr2175252507-0.0006571240.99934286
ENST00000409457ENST00000362053AGAP1chr2236715975+CIR1chr2175252507-0.0012723260.9987276

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Fusion Genomic Features for AGAP1-CIR1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for AGAP1-CIR1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:236715975/chr2:175252507)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAGAP1chr2:236715975chr2:175252507ENST00000304032+918122_126350858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236715975chr2:175252507ENST00000304032+918178_181350858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236715975chr2:175252507ENST00000304032+91878_85350858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236715975chr2:175252507ENST00000336665+917122_126350805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236715975chr2:175252507ENST00000336665+917178_181350805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236715975chr2:175252507ENST00000336665+91778_85350805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236715975chr2:175252507ENST00000409457+910122_126350406.0Nucleotide bindingGTP
HgeneAGAP1chr2:236715975chr2:175252507ENST00000409457+910178_181350406.0Nucleotide bindingGTP
HgeneAGAP1chr2:236715975chr2:175252507ENST00000409457+91078_85350406.0Nucleotide bindingGTP
HgeneAGAP1chr2:236715975chr2:175252507ENST00000304032+91866_276350858.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236715975chr2:175252507ENST00000336665+91766_276350805.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236715975chr2:175252507ENST00000409457+91066_276350406.0RegionNote=Small GTPase-like
TgeneCIR1chr2:236715975chr2:175252507ENST00000342016010214_36824451.0Compositional biasNote=Lys/Ser-rich
TgeneCIR1chr2:236715975chr2:175252507ENST00000342016010369_45024451.0Compositional biasNote=Arg/Ser-rich (RS domain)
TgeneCIR1chr2:236715975chr2:175252507ENST00000362053011214_36824496.3333333333333Compositional biasNote=Lys/Ser-rich
TgeneCIR1chr2:236715975chr2:175252507ENST00000362053011369_45024496.3333333333333Compositional biasNote=Arg/Ser-rich (RS domain)
TgeneCIR1chr2:236715975chr2:175252507ENST00000342016010235_24524451.0MotifNuclear localization signal
TgeneCIR1chr2:236715975chr2:175252507ENST00000342016010291_29824451.0MotifNuclear localization signal
TgeneCIR1chr2:236715975chr2:175252507ENST00000362053011235_24524496.3333333333333MotifNuclear localization signal
TgeneCIR1chr2:236715975chr2:175252507ENST00000362053011291_29824496.3333333333333MotifNuclear localization signal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAGAP1chr2:236715975chr2:175252507ENST00000304032+918346_588350858.0DomainPH
HgeneAGAP1chr2:236715975chr2:175252507ENST00000304032+918609_729350858.0DomainArf-GAP
HgeneAGAP1chr2:236715975chr2:175252507ENST00000336665+917346_588350805.0DomainPH
HgeneAGAP1chr2:236715975chr2:175252507ENST00000336665+917609_729350805.0DomainArf-GAP
HgeneAGAP1chr2:236715975chr2:175252507ENST00000409457+910346_588350406.0DomainPH
HgeneAGAP1chr2:236715975chr2:175252507ENST00000409457+910609_729350406.0DomainArf-GAP
HgeneAGAP1chr2:236715975chr2:175252507ENST00000304032+918768_797350858.0RepeatNote=ANK 1
HgeneAGAP1chr2:236715975chr2:175252507ENST00000304032+918801_830350858.0RepeatNote=ANK 2
HgeneAGAP1chr2:236715975chr2:175252507ENST00000336665+917768_797350805.0RepeatNote=ANK 1
HgeneAGAP1chr2:236715975chr2:175252507ENST00000336665+917801_830350805.0RepeatNote=ANK 2
HgeneAGAP1chr2:236715975chr2:175252507ENST00000409457+910768_797350406.0RepeatNote=ANK 1
HgeneAGAP1chr2:236715975chr2:175252507ENST00000409457+910801_830350406.0RepeatNote=ANK 2
HgeneAGAP1chr2:236715975chr2:175252507ENST00000304032+918624_647350858.0Zinc fingerC4-type
HgeneAGAP1chr2:236715975chr2:175252507ENST00000336665+917624_647350805.0Zinc fingerC4-type
HgeneAGAP1chr2:236715975chr2:175252507ENST00000409457+910624_647350406.0Zinc fingerC4-type


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Fusion Gene Sequence for AGAP1-CIR1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>2763_2763_1_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000304032_CIR1_chr2_175252507_ENST00000342016_length(transcript)=3386nt_BP=1630nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGT
GGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTT
CAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGT
GGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAA
CACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAA
GCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCA
GAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTGCAAGTCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTC
CGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGGGAGTTTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAG
CACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACACGCCCACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCT
GTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCTGGAGAGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCC
AATTAAACAGGTATGGATGGCAGAACAGAAAATATCATATGATAAGAAGAAACAAGAAGAATTGATGCAGCAATATCTTAAAGAACAAGA
ATCATATGATAATAGATTGCTTATGGGAGATGAACGTGTAAAGAATGGCCTTAATTTCATGTATGAAGCCCCACCAGGAGCTAAAAAAGA
AAACAAAGAGAAAGAAGAAACAGAAGGAGAGACCGAATACAAATTTGAATGGCAGAAAGGAGCCCCACGAGAAAAATATGCCAAAGATGA
CATGAACATCAGAGATCAGCCCTTTGGTATTCAGGTTCGAAATGTGAGGTGCATTAAATGTCACAAATGGGGTCATGTCAACACAGATCG
AGAATGTCCTTTGTTTGGTCTTTCTGGAATCAATGCAAGTTCGGTTCCCACTGATGGCTCAGGGCCATCGATGCACCCCTCGGAGCTAAT
AGCGGAGATGAGAAACAGTGGGTTTGCACTGAAACGAAATGTACTGGGGAGAAACTTGACCGCAAATGATCCATCACAGGAGTATGTTGC
AAGTGAGGGTGAAGAAGATCCAGAAGTTGAATTTTTAAAGTCACTAACAACCAAACAAAAACAGAAACTTCTCAGGAAATTAGATCGACT
GGAGAAGAAAAAAAAGAAAAAAGATAGAAAAAAGAAAAAGTTTCAGAAGAGCAGAAGTAAACACAAAAAACATAAGTCCTCTTCTTCCTC
ATCTTCCTCCTCCTCCTCCTCTTCCTCTACTGAGACTTCAGAAAGCAGTAGTGAGAGTGAGAGTAACAATAAAGAAAAAAAAATACAAAG
GAAGAAAAGAAAGAAAAACAAGTGTTCAGGGCATAACAACAGTGATTCTGAAGAGAAGGACAAGTCTAAGAAGAGAAAGCTTCATGAAGA
ACTTTCTAGCAGTCACCATAACCGGGAAAAAGCCAAGGAAAAGCCCAGGTTCTTAAAACACGAGAGTTCTAGGGAGGACAGCAAATGGAG
CCATTCTGATTCTGACAAAAAGTCCAGAACCCATAAACATAGCCCAGAGAAGAGAGGCTCTGAAAGAAAGGAGGGGAGCAGCAGAAGCCA
CGGCAGGGAGGAAAGGAGCCGGAGAAGCCGGAGCAGAAGTCCTGGTAGTTACAAGCAAAGGGAGACAAGGAAACGGGCACAGCGAAATCC
TGGTGAAGAGCAAAGCAGAAGAAATGACAGCAGAAGCCATGGCACAGACTTGTATAGAGGAGAAAAAATGTACAGAGAGCACCCAGGAGG
TACACATACTAAAGTGACACAAAGAGAATGAAGCAGAAGTAGAGAAGAAAGACTGTATGTGACAATTACCTGGGAATAAAAATATCTCCA
CTTTTTTATTGAATACCTTTAGCAAGGGGTAAATTATGTACTGTTGTCTTTCTAATAAAAAAGCTCAATTTTAATTTTTCATCTCTAGAC
TGTCAATTCAAGTACAAAACTACATGAGTACTATAAGAATGAATTTTGCAAATATTTGTAAGTAAGCTATTTTGGGGCTGTGGAAATATT
TTCTGTTGGTAACTGTTTCTTGTTCCCCATACCAGATAAAAACCGCATATAACTCTGTGACATTTTCTTTGTTCTGAAACATCATTAAAA
GAATGACAGTACATTGAATGGGTATAATTTACTTTTTTCAATTCAAATTTGTTATTCTAGGATTTGAATTTGCTTGAAGTGAATTGTAAT
AATTATTCAAATTCATTAGTATAAATTAAGGATTAATAAATCTTTAAGACTTTTAA

>2763_2763_1_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000304032_CIR1_chr2_175252507_ENST00000342016_length(amino acids)=829AA_BP=403
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGG
PPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLN
VERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPV
RKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMGDERVKNGLNFM
YEAPPGAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGS
GPSMHPSELIAEMRNSGFALKRNVLGRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSK
HKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKH
ESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRG
EKMYREHPGGTHTKVTQRE

--------------------------------------------------------------
>2763_2763_2_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000304032_CIR1_chr2_175252507_ENST00000362053_length(transcript)=3284nt_BP=1630nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGT
GGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTT
CAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGT
GGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAA
CACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAA
GCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCA
GAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTGCAAGTCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTC
CGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGGGAGTTTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAG
CACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACACGCCCACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCT
GTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCTGGAGAGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCC
AATTAAACAGGTATGGATGGCAGAACAGAAAATATCATATGATAAGAAGAAACAAGAAGAATTGATGCAGCAATATCTTAAAGAACAAGA
ATCATATGATAATAGATTGCTTATGGGAGATGAACGTGTAAAGAATGGCCTTAATTTCATGTATGAAGCCCCACCAGGAGCTAAAAAAGA
AAACAAAGAGAAAGAAGAAACAGAAGGAGAGACCGAATACAAATTTGAATGGCAGAAAGGAGCCCCACGAGAAAAATATGCCAAAGATGA
CATGAACATCAGAGATCAGCCCTTTGGTATTCAGGTTCGAAATGTGAGGTGCATTAAATGTCACAAATGGGGTCATGTCAACACAGATCG
AGAATGTCCTTTGTTTGGTCTTTCTGGAATCAATGCAAGTTCGGTTCCCACTGATGGCTCAGATGCTGTGTTACAAATTGAAGGTTTCTG
GGCCATCGATGCACCCCTCGGAGCTAATAGCGGAGATGAGAAACAGTGGGTTTGCACTGAAACGAAATGTACTGGGGAGAAACTTGACCG
CAAATGATCCATCACAGGAGTATGTTGCAAGTGAGGGTGAAGAAGATCCAGAAGTTGAATTTTTAAAGTCACTAACAACCAAACAAAAAC
AGAAACTTCTCAGGAAATTAGATCGACTGGAGAAGAAAAAAAAGAAAAAAGATAGAAAAAAGAAAAAGTTTCAGAAGAGCAGAAGTAAAC
ACAAAAAACATAAGTCCTCTTCTTCCTCATCTTCCTCCTCCTCCTCCTCTTCCTCTACTGAGACTTCAGAAAGCAGTAGTGAGAGTGAGA
GTAACAATAAAGAAAAAAAAATACAAAGGAAGAAAAGAAAGAAAAACAAGTGTTCAGGGCATAACAACAGTGATTCTGAAGAGAAGGACA
AGTCTAAGAAGAGAAAGCTTCATGAAGAACTTTCTAGCAGTCACCATAACCGGGAAAAAGCCAAGGAAAAGCCCAGGTTCTTAAAACACG
AGAGTTCTAGGGAGGACAGCAAATGGAGCCATTCTGATTCTGACAAAAAGTCCAGAACCCATAAACATAGCCCAGAGAAGAGAGGCTCTG
AAAGAAAGGAGGGGAGCAGCAGAAGCCACGGCAGGGAGGAAAGGAGCCGGAGAAGCCGGAGCAGAAGTCCTGGTAGTTACAAGCAAAGGG
AGACAAGGAAACGGGCACAGCGAAATCCTGGTGAAGAGCAAAGCAGAAGAAATGACAGCAGAAGCCATGGCACAGACTTGTATAGAGGAG
AAAAAATGTACAGAGAGCACCCAGGAGGTACACATACTAAAGTGACACAAAGAGAATGAAGCAGAAGTAGAGAAGAAAGACTGTATGTGA
CAATTACCTGGGAATAAAAATATCTCCACTTTTTTATTGAATACCTTTAGCAAGGGGTAAATTATGTACTGTTGTCTTTCTAATAAAAAA
GCTCAATTTTAATTTTTCATCTCTAGACTGTCAATTCAAGTACAAAACTACATGAGTACTATAAGAATGAATTTTGCAAATATTTGTAAG
TAAGCTATTTTGGGGCTGTGGAAATATTTTCTGTTGGTAACTGTTTCTTGTTCCCCATACCAGATAAAAACCGCATATAACTCTGTGACA
TTTTCTTTGTTCTGAAACATCATTAAAAGAATGACAGTACATTG

>2763_2763_2_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000304032_CIR1_chr2_175252507_ENST00000362053_length(amino acids)=581AA_BP=403
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGG
PPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLN
VERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPV
RKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMGDERVKNGLNFM
YEAPPGAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGS
DAVLQIEGFWAIDAPLGANSGDEKQWVCTETKCTGEKLDRK

--------------------------------------------------------------
>2763_2763_3_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000336665_CIR1_chr2_175252507_ENST00000342016_length(transcript)=3386nt_BP=1630nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGT
GGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTT
CAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGT
GGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAA
CACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAA
GCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCA
GAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTGCAAGTCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTC
CGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGGGAGTTTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAG
CACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACACGCCCACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCT
GTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCTGGAGAGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCC
AATTAAACAGGTATGGATGGCAGAACAGAAAATATCATATGATAAGAAGAAACAAGAAGAATTGATGCAGCAATATCTTAAAGAACAAGA
ATCATATGATAATAGATTGCTTATGGGAGATGAACGTGTAAAGAATGGCCTTAATTTCATGTATGAAGCCCCACCAGGAGCTAAAAAAGA
AAACAAAGAGAAAGAAGAAACAGAAGGAGAGACCGAATACAAATTTGAATGGCAGAAAGGAGCCCCACGAGAAAAATATGCCAAAGATGA
CATGAACATCAGAGATCAGCCCTTTGGTATTCAGGTTCGAAATGTGAGGTGCATTAAATGTCACAAATGGGGTCATGTCAACACAGATCG
AGAATGTCCTTTGTTTGGTCTTTCTGGAATCAATGCAAGTTCGGTTCCCACTGATGGCTCAGGGCCATCGATGCACCCCTCGGAGCTAAT
AGCGGAGATGAGAAACAGTGGGTTTGCACTGAAACGAAATGTACTGGGGAGAAACTTGACCGCAAATGATCCATCACAGGAGTATGTTGC
AAGTGAGGGTGAAGAAGATCCAGAAGTTGAATTTTTAAAGTCACTAACAACCAAACAAAAACAGAAACTTCTCAGGAAATTAGATCGACT
GGAGAAGAAAAAAAAGAAAAAAGATAGAAAAAAGAAAAAGTTTCAGAAGAGCAGAAGTAAACACAAAAAACATAAGTCCTCTTCTTCCTC
ATCTTCCTCCTCCTCCTCCTCTTCCTCTACTGAGACTTCAGAAAGCAGTAGTGAGAGTGAGAGTAACAATAAAGAAAAAAAAATACAAAG
GAAGAAAAGAAAGAAAAACAAGTGTTCAGGGCATAACAACAGTGATTCTGAAGAGAAGGACAAGTCTAAGAAGAGAAAGCTTCATGAAGA
ACTTTCTAGCAGTCACCATAACCGGGAAAAAGCCAAGGAAAAGCCCAGGTTCTTAAAACACGAGAGTTCTAGGGAGGACAGCAAATGGAG
CCATTCTGATTCTGACAAAAAGTCCAGAACCCATAAACATAGCCCAGAGAAGAGAGGCTCTGAAAGAAAGGAGGGGAGCAGCAGAAGCCA
CGGCAGGGAGGAAAGGAGCCGGAGAAGCCGGAGCAGAAGTCCTGGTAGTTACAAGCAAAGGGAGACAAGGAAACGGGCACAGCGAAATCC
TGGTGAAGAGCAAAGCAGAAGAAATGACAGCAGAAGCCATGGCACAGACTTGTATAGAGGAGAAAAAATGTACAGAGAGCACCCAGGAGG
TACACATACTAAAGTGACACAAAGAGAATGAAGCAGAAGTAGAGAAGAAAGACTGTATGTGACAATTACCTGGGAATAAAAATATCTCCA
CTTTTTTATTGAATACCTTTAGCAAGGGGTAAATTATGTACTGTTGTCTTTCTAATAAAAAAGCTCAATTTTAATTTTTCATCTCTAGAC
TGTCAATTCAAGTACAAAACTACATGAGTACTATAAGAATGAATTTTGCAAATATTTGTAAGTAAGCTATTTTGGGGCTGTGGAAATATT
TTCTGTTGGTAACTGTTTCTTGTTCCCCATACCAGATAAAAACCGCATATAACTCTGTGACATTTTCTTTGTTCTGAAACATCATTAAAA
GAATGACAGTACATTGAATGGGTATAATTTACTTTTTTCAATTCAAATTTGTTATTCTAGGATTTGAATTTGCTTGAAGTGAATTGTAAT
AATTATTCAAATTCATTAGTATAAATTAAGGATTAATAAATCTTTAAGACTTTTAA

>2763_2763_3_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000336665_CIR1_chr2_175252507_ENST00000342016_length(amino acids)=829AA_BP=403
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGG
PPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLN
VERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPV
RKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMGDERVKNGLNFM
YEAPPGAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGS
GPSMHPSELIAEMRNSGFALKRNVLGRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSK
HKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKH
ESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRG
EKMYREHPGGTHTKVTQRE

--------------------------------------------------------------
>2763_2763_4_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000336665_CIR1_chr2_175252507_ENST00000362053_length(transcript)=3284nt_BP=1630nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGT
GGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTT
CAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGT
GGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAA
CACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAA
GCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCA
GAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTGCAAGTCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTC
CGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGGGAGTTTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAG
CACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACACGCCCACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCT
GTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCTGGAGAGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCC
AATTAAACAGGTATGGATGGCAGAACAGAAAATATCATATGATAAGAAGAAACAAGAAGAATTGATGCAGCAATATCTTAAAGAACAAGA
ATCATATGATAATAGATTGCTTATGGGAGATGAACGTGTAAAGAATGGCCTTAATTTCATGTATGAAGCCCCACCAGGAGCTAAAAAAGA
AAACAAAGAGAAAGAAGAAACAGAAGGAGAGACCGAATACAAATTTGAATGGCAGAAAGGAGCCCCACGAGAAAAATATGCCAAAGATGA
CATGAACATCAGAGATCAGCCCTTTGGTATTCAGGTTCGAAATGTGAGGTGCATTAAATGTCACAAATGGGGTCATGTCAACACAGATCG
AGAATGTCCTTTGTTTGGTCTTTCTGGAATCAATGCAAGTTCGGTTCCCACTGATGGCTCAGATGCTGTGTTACAAATTGAAGGTTTCTG
GGCCATCGATGCACCCCTCGGAGCTAATAGCGGAGATGAGAAACAGTGGGTTTGCACTGAAACGAAATGTACTGGGGAGAAACTTGACCG
CAAATGATCCATCACAGGAGTATGTTGCAAGTGAGGGTGAAGAAGATCCAGAAGTTGAATTTTTAAAGTCACTAACAACCAAACAAAAAC
AGAAACTTCTCAGGAAATTAGATCGACTGGAGAAGAAAAAAAAGAAAAAAGATAGAAAAAAGAAAAAGTTTCAGAAGAGCAGAAGTAAAC
ACAAAAAACATAAGTCCTCTTCTTCCTCATCTTCCTCCTCCTCCTCCTCTTCCTCTACTGAGACTTCAGAAAGCAGTAGTGAGAGTGAGA
GTAACAATAAAGAAAAAAAAATACAAAGGAAGAAAAGAAAGAAAAACAAGTGTTCAGGGCATAACAACAGTGATTCTGAAGAGAAGGACA
AGTCTAAGAAGAGAAAGCTTCATGAAGAACTTTCTAGCAGTCACCATAACCGGGAAAAAGCCAAGGAAAAGCCCAGGTTCTTAAAACACG
AGAGTTCTAGGGAGGACAGCAAATGGAGCCATTCTGATTCTGACAAAAAGTCCAGAACCCATAAACATAGCCCAGAGAAGAGAGGCTCTG
AAAGAAAGGAGGGGAGCAGCAGAAGCCACGGCAGGGAGGAAAGGAGCCGGAGAAGCCGGAGCAGAAGTCCTGGTAGTTACAAGCAAAGGG
AGACAAGGAAACGGGCACAGCGAAATCCTGGTGAAGAGCAAAGCAGAAGAAATGACAGCAGAAGCCATGGCACAGACTTGTATAGAGGAG
AAAAAATGTACAGAGAGCACCCAGGAGGTACACATACTAAAGTGACACAAAGAGAATGAAGCAGAAGTAGAGAAGAAAGACTGTATGTGA
CAATTACCTGGGAATAAAAATATCTCCACTTTTTTATTGAATACCTTTAGCAAGGGGTAAATTATGTACTGTTGTCTTTCTAATAAAAAA
GCTCAATTTTAATTTTTCATCTCTAGACTGTCAATTCAAGTACAAAACTACATGAGTACTATAAGAATGAATTTTGCAAATATTTGTAAG
TAAGCTATTTTGGGGCTGTGGAAATATTTTCTGTTGGTAACTGTTTCTTGTTCCCCATACCAGATAAAAACCGCATATAACTCTGTGACA
TTTTCTTTGTTCTGAAACATCATTAAAAGAATGACAGTACATTG

>2763_2763_4_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000336665_CIR1_chr2_175252507_ENST00000362053_length(amino acids)=581AA_BP=403
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGG
PPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLN
VERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPV
RKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMGDERVKNGLNFM
YEAPPGAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGS
DAVLQIEGFWAIDAPLGANSGDEKQWVCTETKCTGEKLDRK

--------------------------------------------------------------
>2763_2763_5_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000409457_CIR1_chr2_175252507_ENST00000342016_length(transcript)=3404nt_BP=1648nt
GGCGCTCGGAGCGGGCTCCGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCC
CGGCGCGCCGGGCGGCGCAGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGC
CCTCGGCCCCGGCGCTCGGAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGC
TCAGGAAGTCACCCGAGCAAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGC
TGACCCGGGACGCCGGGGCCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCC
GCGCCTTTCTTCTCGCGCCTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCC
CCGGGGCGCGGGGCGGCGGCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGC
TGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGT
GCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGA
GCTCAAAGTGGGAATTGTGGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTC
TCCGGAAGGTGGCAGGTTCAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGC
GCAGTTTGCCATGTGGGTGGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCG
AATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGA
TGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGT
CTTCCAGGACGTTGCCCAGAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTGCAAGTCGCTACCTAATTCTCCCAG
CCATTCCTCCGTCTGTTCCGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGGGAGTTTAAGCGACTATTCCTCCTC
CGTTCCATCGACTCCCAGCACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACACGCCCACGCCCGTTCGCAAGCAGTC
TAAGCGCCGGTCCAACCTGTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCTGGAGAGTCGTGCGGACAGCATTGG
GAGCGGCCGAGCCATCCCAATTAAACAGGTATGGATGGCAGAACAGAAAATATCATATGATAAGAAGAAACAAGAAGAATTGATGCAGCA
ATATCTTAAAGAACAAGAATCATATGATAATAGATTGCTTATGGGAGATGAACGTGTAAAGAATGGCCTTAATTTCATGTATGAAGCCCC
ACCAGGAGCTAAAAAAGAAAACAAAGAGAAAGAAGAAACAGAAGGAGAGACCGAATACAAATTTGAATGGCAGAAAGGAGCCCCACGAGA
AAAATATGCCAAAGATGACATGAACATCAGAGATCAGCCCTTTGGTATTCAGGTTCGAAATGTGAGGTGCATTAAATGTCACAAATGGGG
TCATGTCAACACAGATCGAGAATGTCCTTTGTTTGGTCTTTCTGGAATCAATGCAAGTTCGGTTCCCACTGATGGCTCAGGGCCATCGAT
GCACCCCTCGGAGCTAATAGCGGAGATGAGAAACAGTGGGTTTGCACTGAAACGAAATGTACTGGGGAGAAACTTGACCGCAAATGATCC
ATCACAGGAGTATGTTGCAAGTGAGGGTGAAGAAGATCCAGAAGTTGAATTTTTAAAGTCACTAACAACCAAACAAAAACAGAAACTTCT
CAGGAAATTAGATCGACTGGAGAAGAAAAAAAAGAAAAAAGATAGAAAAAAGAAAAAGTTTCAGAAGAGCAGAAGTAAACACAAAAAACA
TAAGTCCTCTTCTTCCTCATCTTCCTCCTCCTCCTCCTCTTCCTCTACTGAGACTTCAGAAAGCAGTAGTGAGAGTGAGAGTAACAATAA
AGAAAAAAAAATACAAAGGAAGAAAAGAAAGAAAAACAAGTGTTCAGGGCATAACAACAGTGATTCTGAAGAGAAGGACAAGTCTAAGAA
GAGAAAGCTTCATGAAGAACTTTCTAGCAGTCACCATAACCGGGAAAAAGCCAAGGAAAAGCCCAGGTTCTTAAAACACGAGAGTTCTAG
GGAGGACAGCAAATGGAGCCATTCTGATTCTGACAAAAAGTCCAGAACCCATAAACATAGCCCAGAGAAGAGAGGCTCTGAAAGAAAGGA
GGGGAGCAGCAGAAGCCACGGCAGGGAGGAAAGGAGCCGGAGAAGCCGGAGCAGAAGTCCTGGTAGTTACAAGCAAAGGGAGACAAGGAA
ACGGGCACAGCGAAATCCTGGTGAAGAGCAAAGCAGAAGAAATGACAGCAGAAGCCATGGCACAGACTTGTATAGAGGAGAAAAAATGTA
CAGAGAGCACCCAGGAGGTACACATACTAAAGTGACACAAAGAGAATGAAGCAGAAGTAGAGAAGAAAGACTGTATGTGACAATTACCTG
GGAATAAAAATATCTCCACTTTTTTATTGAATACCTTTAGCAAGGGGTAAATTATGTACTGTTGTCTTTCTAATAAAAAAGCTCAATTTT
AATTTTTCATCTCTAGACTGTCAATTCAAGTACAAAACTACATGAGTACTATAAGAATGAATTTTGCAAATATTTGTAAGTAAGCTATTT
TGGGGCTGTGGAAATATTTTCTGTTGGTAACTGTTTCTTGTTCCCCATACCAGATAAAAACCGCATATAACTCTGTGACATTTTCTTTGT
TCTGAAACATCATTAAAAGAATGACAGTACATTGAATGGGTATAATTTACTTTTTTCAATTCAAATTTGTTATTCTAGGATTTGAATTTG
CTTGAAGTGAATTGTAATAATTATTCAAATTCATTAGTATAAATTAAGGATTAATAAATCTTTAAGACTTTTAA

>2763_2763_5_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000409457_CIR1_chr2_175252507_ENST00000342016_length(amino acids)=829AA_BP=403
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGG
PPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLN
VERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPV
RKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMGDERVKNGLNFM
YEAPPGAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGS
GPSMHPSELIAEMRNSGFALKRNVLGRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSK
HKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKH
ESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRG
EKMYREHPGGTHTKVTQRE

--------------------------------------------------------------
>2763_2763_6_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000409457_CIR1_chr2_175252507_ENST00000362053_length(transcript)=3302nt_BP=1648nt
GGCGCTCGGAGCGGGCTCCGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCC
CGGCGCGCCGGGCGGCGCAGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGC
CCTCGGCCCCGGCGCTCGGAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGC
TCAGGAAGTCACCCGAGCAAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGC
TGACCCGGGACGCCGGGGCCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCC
GCGCCTTTCTTCTCGCGCCTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCC
CCGGGGCGCGGGGCGGCGGCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGC
TGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGT
GCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGA
GCTCAAAGTGGGAATTGTGGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTC
TCCGGAAGGTGGCAGGTTCAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGC
GCAGTTTGCCATGTGGGTGGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCG
AATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGA
TGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGT
CTTCCAGGACGTTGCCCAGAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTGCAAGTCGCTACCTAATTCTCCCAG
CCATTCCTCCGTCTGTTCCGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGGGAGTTTAAGCGACTATTCCTCCTC
CGTTCCATCGACTCCCAGCACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACACGCCCACGCCCGTTCGCAAGCAGTC
TAAGCGCCGGTCCAACCTGTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCTGGAGAGTCGTGCGGACAGCATTGG
GAGCGGCCGAGCCATCCCAATTAAACAGGTATGGATGGCAGAACAGAAAATATCATATGATAAGAAGAAACAAGAAGAATTGATGCAGCA
ATATCTTAAAGAACAAGAATCATATGATAATAGATTGCTTATGGGAGATGAACGTGTAAAGAATGGCCTTAATTTCATGTATGAAGCCCC
ACCAGGAGCTAAAAAAGAAAACAAAGAGAAAGAAGAAACAGAAGGAGAGACCGAATACAAATTTGAATGGCAGAAAGGAGCCCCACGAGA
AAAATATGCCAAAGATGACATGAACATCAGAGATCAGCCCTTTGGTATTCAGGTTCGAAATGTGAGGTGCATTAAATGTCACAAATGGGG
TCATGTCAACACAGATCGAGAATGTCCTTTGTTTGGTCTTTCTGGAATCAATGCAAGTTCGGTTCCCACTGATGGCTCAGATGCTGTGTT
ACAAATTGAAGGTTTCTGGGCCATCGATGCACCCCTCGGAGCTAATAGCGGAGATGAGAAACAGTGGGTTTGCACTGAAACGAAATGTAC
TGGGGAGAAACTTGACCGCAAATGATCCATCACAGGAGTATGTTGCAAGTGAGGGTGAAGAAGATCCAGAAGTTGAATTTTTAAAGTCAC
TAACAACCAAACAAAAACAGAAACTTCTCAGGAAATTAGATCGACTGGAGAAGAAAAAAAAGAAAAAAGATAGAAAAAAGAAAAAGTTTC
AGAAGAGCAGAAGTAAACACAAAAAACATAAGTCCTCTTCTTCCTCATCTTCCTCCTCCTCCTCCTCTTCCTCTACTGAGACTTCAGAAA
GCAGTAGTGAGAGTGAGAGTAACAATAAAGAAAAAAAAATACAAAGGAAGAAAAGAAAGAAAAACAAGTGTTCAGGGCATAACAACAGTG
ATTCTGAAGAGAAGGACAAGTCTAAGAAGAGAAAGCTTCATGAAGAACTTTCTAGCAGTCACCATAACCGGGAAAAAGCCAAGGAAAAGC
CCAGGTTCTTAAAACACGAGAGTTCTAGGGAGGACAGCAAATGGAGCCATTCTGATTCTGACAAAAAGTCCAGAACCCATAAACATAGCC
CAGAGAAGAGAGGCTCTGAAAGAAAGGAGGGGAGCAGCAGAAGCCACGGCAGGGAGGAAAGGAGCCGGAGAAGCCGGAGCAGAAGTCCTG
GTAGTTACAAGCAAAGGGAGACAAGGAAACGGGCACAGCGAAATCCTGGTGAAGAGCAAAGCAGAAGAAATGACAGCAGAAGCCATGGCA
CAGACTTGTATAGAGGAGAAAAAATGTACAGAGAGCACCCAGGAGGTACACATACTAAAGTGACACAAAGAGAATGAAGCAGAAGTAGAG
AAGAAAGACTGTATGTGACAATTACCTGGGAATAAAAATATCTCCACTTTTTTATTGAATACCTTTAGCAAGGGGTAAATTATGTACTGT
TGTCTTTCTAATAAAAAAGCTCAATTTTAATTTTTCATCTCTAGACTGTCAATTCAAGTACAAAACTACATGAGTACTATAAGAATGAAT
TTTGCAAATATTTGTAAGTAAGCTATTTTGGGGCTGTGGAAATATTTTCTGTTGGTAACTGTTTCTTGTTCCCCATACCAGATAAAAACC
GCATATAACTCTGTGACATTTTCTTTGTTCTGAAACATCATTAAAAGAATGACAGTACATTG

>2763_2763_6_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000409457_CIR1_chr2_175252507_ENST00000362053_length(amino acids)=581AA_BP=403
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGG
PPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLN
VERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPV
RKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMGDERVKNGLNFM
YEAPPGAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGS
DAVLQIEGFWAIDAPLGANSGDEKQWVCTETKCTGEKLDRK

--------------------------------------------------------------
>2763_2763_7_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000409538_CIR1_chr2_175252507_ENST00000342016_length(transcript)=4097nt_BP=2341nt
GCGCGTTTCCATTTTAAACCGCCGCCCGCCGCCCGCCACCCGCCACCCTTCGGCCGCAGCCGGTGCAGCTGTCCGCGCGTCCCGGAGCCC
AGGGAGTGGCGGAGGCTGCGGAACCGCCGAGCTGTGCAGCCGGAGCGGGAGGATGCGCACGGGCCCCGCGTCGTAGACAATGAAGCCGCG
GGCGCCGCCGCCTGCCCTGGGCCCTGCGCACCGCGGCCGCACCTGCCGGCGAGAGCGCTCTAGCGCCTGACCGGCCGCCTCGCTTGGCCC
CGCCGGCCCATGGCTCGGCGCCCCGGGCCCGGACCCCGGCACTCGGGCGGCGCGGCGCACGGGCCGGCGGGTGCCAGGGGCGCCGTCCCC
GCAGCCTGAGTGCGGCCCTCGCGGTCAGCGGGGGGCGTGGGCCACACTCCCGGCCCGCCTGCCCTCCCCGCTTGGCCCGGCGCCCTCCCG
GCCCGCGGGCTCGCTGGATGCGGCGGGGCCCCAGCGCGCGGGCGACATGTACTTGTTGGACGGCAGTGGCGAGCCCGCGTCGCCACCCGC
GGACGCGATGCCGCGCGGGACGCCCCCCAGAAAGACTGTCTACCGCATCTCCGTGACCATGGTCAGGAAGGAGCAGCTGGCCGCGCCGGG
CTCCGGCGGCCCGGACCCACGCCCGGTTCGGCGGCCCCGGCCCGCGCGCTCCCCGGACGCGCCCGGGAGGCTTGAGGAGGAGGCCGAGGA
GGCGGAGGGCGCCGAGGAACCGGAGGGTCCCCGGCCGCGCGCTTGGGATTTCCGCACCTTCCGCACCCGCAGCACCGGGCAGCTGGAACT
GGGGCGGCTCCGGCCGTGCGCACGCGGCCTGGAACCCGCGGACCTGGCCGGCAGCGCCCCGGCCGAGGAGGAGGGACGCGGCTCGCCCGC
GTCCGGCAGCCCCGACGTGGAGGGGGCCCGGGCCGCGCCCCTGCGGCGGAGCCTGAGCTTCAGGCACTGGAGCGGGCCTGAGGCGCCGCA
AGGCCGGACACTGGGCGGCGGAAGGCGCCACAGCAGCTCCGGGAGCCTGGCCTGGGCGCCGTGCGACGAGGCCGCGGCCGGGACCACCCT
GGAGCCCGCGACCGCCACGCAGCCCGCCTCGGAGAAGCGCAACACCCTGGACGTGGGCGAGGTGCTCAGCAAGAACGACGCGCTCTCGGA
CCTGGAGCGTTGGGAACGCAGTAAGAGCAAGAACCGCACGCTGGACAACAGCGACCTGCAGCGGCTGGAGCGCGCGCGGGCGGCGGCCGG
GGCCGGCGCGGCCTCGGAGCACCGGCTGCTGCGCTTCTTCAGCGGCATCTTCGCGCGCAGGGACGGGGGCCCGGGCGGCGGGCCCTCGCC
ACGGAGCGGAGCCTCGCGGCCACGCGGCTACTTCAGCCTGCGGCGGGCCCCGGCCGAAGCGCACTCGTCCAGCGCCGAGAGCATCGACGG
CTCCCCGCGCAGAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGTGGGTAACTT
GGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTTCAAGAAAGA
GATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGTGGACGCTGT
TATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGA
GATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAA
CGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCAGAAGATTGT
TGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTGCAAGTCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTCCGCGCAGGT
GTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGGGAGTTTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAGCACCAGCCA
GAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACACGCCCACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCTGTTCACCTC
TCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCTGGAGAGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCCAATTAAACA
GGTATGGATGGCAGAACAGAAAATATCATATGATAAGAAGAAACAAGAAGAATTGATGCAGCAATATCTTAAAGAACAAGAATCATATGA
TAATAGATTGCTTATGGGAGATGAACGTGTAAAGAATGGCCTTAATTTCATGTATGAAGCCCCACCAGGAGCTAAAAAAGAAAACAAAGA
GAAAGAAGAAACAGAAGGAGAGACCGAATACAAATTTGAATGGCAGAAAGGAGCCCCACGAGAAAAATATGCCAAAGATGACATGAACAT
CAGAGATCAGCCCTTTGGTATTCAGGTTCGAAATGTGAGGTGCATTAAATGTCACAAATGGGGTCATGTCAACACAGATCGAGAATGTCC
TTTGTTTGGTCTTTCTGGAATCAATGCAAGTTCGGTTCCCACTGATGGCTCAGGGCCATCGATGCACCCCTCGGAGCTAATAGCGGAGAT
GAGAAACAGTGGGTTTGCACTGAAACGAAATGTACTGGGGAGAAACTTGACCGCAAATGATCCATCACAGGAGTATGTTGCAAGTGAGGG
TGAAGAAGATCCAGAAGTTGAATTTTTAAAGTCACTAACAACCAAACAAAAACAGAAACTTCTCAGGAAATTAGATCGACTGGAGAAGAA
AAAAAAGAAAAAAGATAGAAAAAAGAAAAAGTTTCAGAAGAGCAGAAGTAAACACAAAAAACATAAGTCCTCTTCTTCCTCATCTTCCTC
CTCCTCCTCCTCTTCCTCTACTGAGACTTCAGAAAGCAGTAGTGAGAGTGAGAGTAACAATAAAGAAAAAAAAATACAAAGGAAGAAAAG
AAAGAAAAACAAGTGTTCAGGGCATAACAACAGTGATTCTGAAGAGAAGGACAAGTCTAAGAAGAGAAAGCTTCATGAAGAACTTTCTAG
CAGTCACCATAACCGGGAAAAAGCCAAGGAAAAGCCCAGGTTCTTAAAACACGAGAGTTCTAGGGAGGACAGCAAATGGAGCCATTCTGA
TTCTGACAAAAAGTCCAGAACCCATAAACATAGCCCAGAGAAGAGAGGCTCTGAAAGAAAGGAGGGGAGCAGCAGAAGCCACGGCAGGGA
GGAAAGGAGCCGGAGAAGCCGGAGCAGAAGTCCTGGTAGTTACAAGCAAAGGGAGACAAGGAAACGGGCACAGCGAAATCCTGGTGAAGA
GCAAAGCAGAAGAAATGACAGCAGAAGCCATGGCACAGACTTGTATAGAGGAGAAAAAATGTACAGAGAGCACCCAGGAGGTACACATAC
TAAAGTGACACAAAGAGAATGAAGCAGAAGTAGAGAAGAAAGACTGTATGTGACAATTACCTGGGAATAAAAATATCTCCACTTTTTTAT
TGAATACCTTTAGCAAGGGGTAAATTATGTACTGTTGTCTTTCTAATAAAAAAGCTCAATTTTAATTTTTCATCTCTAGACTGTCAATTC
AAGTACAAAACTACATGAGTACTATAAGAATGAATTTTGCAAATATTTGTAAGTAAGCTATTTTGGGGCTGTGGAAATATTTTCTGTTGG
TAACTGTTTCTTGTTCCCCATACCAGATAAAAACCGCATATAACTCTGTGACATTTTCTTTGTTCTGAAACATCATTAAAAGAATGACAG
TACATTGAATGGGTATAATTTACTTTTTTCAATTCAAATTTGTTATTCTAGGATTTGAATTTGCTTGAAGTGAATTGTAATAATTATTCA
AATTCATTAGTATAAATTAAGGATTAATAAATCTTTAAGACTTTTAA

>2763_2763_7_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000409538_CIR1_chr2_175252507_ENST00000342016_length(amino acids)=1067AA_BP=641
MPSPLGPAPSRPAGSLDAAGPQRAGDMYLLDGSGEPASPPADAMPRGTPPRKTVYRISVTMVRKEQLAAPGSGGPDPRPVRRPRPARSPD
APGRLEEEAEEAEGAEEPEGPRPRAWDFRTFRTRSTGQLELGRLRPCARGLEPADLAGSAPAEEEGRGSPASGSPDVEGARAAPLRRSLS
FRHWSGPEAPQGRTLGGGRRHSSSGSLAWAPCDEAAAGTTLEPATATQPASEKRNTLDVGEVLSKNDALSDLERWERSKSKNRTLDNSDL
QRLERARAAAGAGAASEHRLLRFFSGIFARRDGGPGGGPSPRSGASRPRGYFSLRRAPAEAHSSSAESIDGSPRRDAFVNSQEWTLSRSV
PELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYY
SRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNS
PSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADS
IGSGRAIPIKQVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMGDERVKNGLNFMYEAPPGAKKENKEKEETEGETEYKFEWQKGAP
REKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGSGPSMHPSELIAEMRNSGFALKRNVLGRNLTAN
DPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESN
NKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSER
KEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTHTKVTQRE

--------------------------------------------------------------
>2763_2763_8_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000409538_CIR1_chr2_175252507_ENST00000362053_length(transcript)=3995nt_BP=2341nt
GCGCGTTTCCATTTTAAACCGCCGCCCGCCGCCCGCCACCCGCCACCCTTCGGCCGCAGCCGGTGCAGCTGTCCGCGCGTCCCGGAGCCC
AGGGAGTGGCGGAGGCTGCGGAACCGCCGAGCTGTGCAGCCGGAGCGGGAGGATGCGCACGGGCCCCGCGTCGTAGACAATGAAGCCGCG
GGCGCCGCCGCCTGCCCTGGGCCCTGCGCACCGCGGCCGCACCTGCCGGCGAGAGCGCTCTAGCGCCTGACCGGCCGCCTCGCTTGGCCC
CGCCGGCCCATGGCTCGGCGCCCCGGGCCCGGACCCCGGCACTCGGGCGGCGCGGCGCACGGGCCGGCGGGTGCCAGGGGCGCCGTCCCC
GCAGCCTGAGTGCGGCCCTCGCGGTCAGCGGGGGGCGTGGGCCACACTCCCGGCCCGCCTGCCCTCCCCGCTTGGCCCGGCGCCCTCCCG
GCCCGCGGGCTCGCTGGATGCGGCGGGGCCCCAGCGCGCGGGCGACATGTACTTGTTGGACGGCAGTGGCGAGCCCGCGTCGCCACCCGC
GGACGCGATGCCGCGCGGGACGCCCCCCAGAAAGACTGTCTACCGCATCTCCGTGACCATGGTCAGGAAGGAGCAGCTGGCCGCGCCGGG
CTCCGGCGGCCCGGACCCACGCCCGGTTCGGCGGCCCCGGCCCGCGCGCTCCCCGGACGCGCCCGGGAGGCTTGAGGAGGAGGCCGAGGA
GGCGGAGGGCGCCGAGGAACCGGAGGGTCCCCGGCCGCGCGCTTGGGATTTCCGCACCTTCCGCACCCGCAGCACCGGGCAGCTGGAACT
GGGGCGGCTCCGGCCGTGCGCACGCGGCCTGGAACCCGCGGACCTGGCCGGCAGCGCCCCGGCCGAGGAGGAGGGACGCGGCTCGCCCGC
GTCCGGCAGCCCCGACGTGGAGGGGGCCCGGGCCGCGCCCCTGCGGCGGAGCCTGAGCTTCAGGCACTGGAGCGGGCCTGAGGCGCCGCA
AGGCCGGACACTGGGCGGCGGAAGGCGCCACAGCAGCTCCGGGAGCCTGGCCTGGGCGCCGTGCGACGAGGCCGCGGCCGGGACCACCCT
GGAGCCCGCGACCGCCACGCAGCCCGCCTCGGAGAAGCGCAACACCCTGGACGTGGGCGAGGTGCTCAGCAAGAACGACGCGCTCTCGGA
CCTGGAGCGTTGGGAACGCAGTAAGAGCAAGAACCGCACGCTGGACAACAGCGACCTGCAGCGGCTGGAGCGCGCGCGGGCGGCGGCCGG
GGCCGGCGCGGCCTCGGAGCACCGGCTGCTGCGCTTCTTCAGCGGCATCTTCGCGCGCAGGGACGGGGGCCCGGGCGGCGGGCCCTCGCC
ACGGAGCGGAGCCTCGCGGCCACGCGGCTACTTCAGCCTGCGGCGGGCCCCGGCCGAAGCGCACTCGTCCAGCGCCGAGAGCATCGACGG
CTCCCCGCGCAGAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGTGGGTAACTT
GGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTTCAAGAAAGA
GATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGTGGACGCTGT
TATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGA
GATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAA
CGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCAGAAGATTGT
TGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTGCAAGTCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTCCGCGCAGGT
GTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGGGAGTTTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAGCACCAGCCA
GAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACACGCCCACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCTGTTCACCTC
TCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCTGGAGAGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCCAATTAAACA
GGTATGGATGGCAGAACAGAAAATATCATATGATAAGAAGAAACAAGAAGAATTGATGCAGCAATATCTTAAAGAACAAGAATCATATGA
TAATAGATTGCTTATGGGAGATGAACGTGTAAAGAATGGCCTTAATTTCATGTATGAAGCCCCACCAGGAGCTAAAAAAGAAAACAAAGA
GAAAGAAGAAACAGAAGGAGAGACCGAATACAAATTTGAATGGCAGAAAGGAGCCCCACGAGAAAAATATGCCAAAGATGACATGAACAT
CAGAGATCAGCCCTTTGGTATTCAGGTTCGAAATGTGAGGTGCATTAAATGTCACAAATGGGGTCATGTCAACACAGATCGAGAATGTCC
TTTGTTTGGTCTTTCTGGAATCAATGCAAGTTCGGTTCCCACTGATGGCTCAGATGCTGTGTTACAAATTGAAGGTTTCTGGGCCATCGA
TGCACCCCTCGGAGCTAATAGCGGAGATGAGAAACAGTGGGTTTGCACTGAAACGAAATGTACTGGGGAGAAACTTGACCGCAAATGATC
CATCACAGGAGTATGTTGCAAGTGAGGGTGAAGAAGATCCAGAAGTTGAATTTTTAAAGTCACTAACAACCAAACAAAAACAGAAACTTC
TCAGGAAATTAGATCGACTGGAGAAGAAAAAAAAGAAAAAAGATAGAAAAAAGAAAAAGTTTCAGAAGAGCAGAAGTAAACACAAAAAAC
ATAAGTCCTCTTCTTCCTCATCTTCCTCCTCCTCCTCCTCTTCCTCTACTGAGACTTCAGAAAGCAGTAGTGAGAGTGAGAGTAACAATA
AAGAAAAAAAAATACAAAGGAAGAAAAGAAAGAAAAACAAGTGTTCAGGGCATAACAACAGTGATTCTGAAGAGAAGGACAAGTCTAAGA
AGAGAAAGCTTCATGAAGAACTTTCTAGCAGTCACCATAACCGGGAAAAAGCCAAGGAAAAGCCCAGGTTCTTAAAACACGAGAGTTCTA
GGGAGGACAGCAAATGGAGCCATTCTGATTCTGACAAAAAGTCCAGAACCCATAAACATAGCCCAGAGAAGAGAGGCTCTGAAAGAAAGG
AGGGGAGCAGCAGAAGCCACGGCAGGGAGGAAAGGAGCCGGAGAAGCCGGAGCAGAAGTCCTGGTAGTTACAAGCAAAGGGAGACAAGGA
AACGGGCACAGCGAAATCCTGGTGAAGAGCAAAGCAGAAGAAATGACAGCAGAAGCCATGGCACAGACTTGTATAGAGGAGAAAAAATGT
ACAGAGAGCACCCAGGAGGTACACATACTAAAGTGACACAAAGAGAATGAAGCAGAAGTAGAGAAGAAAGACTGTATGTGACAATTACCT
GGGAATAAAAATATCTCCACTTTTTTATTGAATACCTTTAGCAAGGGGTAAATTATGTACTGTTGTCTTTCTAATAAAAAAGCTCAATTT
TAATTTTTCATCTCTAGACTGTCAATTCAAGTACAAAACTACATGAGTACTATAAGAATGAATTTTGCAAATATTTGTAAGTAAGCTATT
TTGGGGCTGTGGAAATATTTTCTGTTGGTAACTGTTTCTTGTTCCCCATACCAGATAAAAACCGCATATAACTCTGTGACATTTTCTTTG
TTCTGAAACATCATTAAAAGAATGACAGTACATTG

>2763_2763_8_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000409538_CIR1_chr2_175252507_ENST00000362053_length(amino acids)=819AA_BP=641
MPSPLGPAPSRPAGSLDAAGPQRAGDMYLLDGSGEPASPPADAMPRGTPPRKTVYRISVTMVRKEQLAAPGSGGPDPRPVRRPRPARSPD
APGRLEEEAEEAEGAEEPEGPRPRAWDFRTFRTRSTGQLELGRLRPCARGLEPADLAGSAPAEEEGRGSPASGSPDVEGARAAPLRRSLS
FRHWSGPEAPQGRTLGGGRRHSSSGSLAWAPCDEAAAGTTLEPATATQPASEKRNTLDVGEVLSKNDALSDLERWERSKSKNRTLDNSDL
QRLERARAAAGAGAASEHRLLRFFSGIFARRDGGPGGGPSPRSGASRPRGYFSLRRAPAEAHSSSAESIDGSPRRDAFVNSQEWTLSRSV
PELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYY
SRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNS
PSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADS
IGSGRAIPIKQVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMGDERVKNGLNFMYEAPPGAKKENKEKEETEGETEYKFEWQKGAP
REKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGSDAVLQIEGFWAIDAPLGANSGDEKQWVCTETK
CTGEKLDRK

--------------------------------------------------------------
>2763_2763_9_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000428334_CIR1_chr2_175252507_ENST00000342016_length(transcript)=2344nt_BP=588nt
GTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCT
GCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATAC
GGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCAGAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTGCAAG
TCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTCCGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGGGAGT
TTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAGCACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACACGCCC
ACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCTGTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCTGGAG
AGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCCAATTAAACAGGTATGGATGGCAGAACAGAAAATATCATATGATAAGAAGAAA
CAAGAAGAATTGATGCAGCAATATCTTAAAGAACAAGAATCATATGATAATAGATTGCTTATGGGAGATGAACGTGTAAAGAATGGCCTT
AATTTCATGTATGAAGCCCCACCAGGAGCTAAAAAAGAAAACAAAGAGAAAGAAGAAACAGAAGGAGAGACCGAATACAAATTTGAATGG
CAGAAAGGAGCCCCACGAGAAAAATATGCCAAAGATGACATGAACATCAGAGATCAGCCCTTTGGTATTCAGGTTCGAAATGTGAGGTGC
ATTAAATGTCACAAATGGGGTCATGTCAACACAGATCGAGAATGTCCTTTGTTTGGTCTTTCTGGAATCAATGCAAGTTCGGTTCCCACT
GATGGCTCAGGGCCATCGATGCACCCCTCGGAGCTAATAGCGGAGATGAGAAACAGTGGGTTTGCACTGAAACGAAATGTACTGGGGAGA
AACTTGACCGCAAATGATCCATCACAGGAGTATGTTGCAAGTGAGGGTGAAGAAGATCCAGAAGTTGAATTTTTAAAGTCACTAACAACC
AAACAAAAACAGAAACTTCTCAGGAAATTAGATCGACTGGAGAAGAAAAAAAAGAAAAAAGATAGAAAAAAGAAAAAGTTTCAGAAGAGC
AGAAGTAAACACAAAAAACATAAGTCCTCTTCTTCCTCATCTTCCTCCTCCTCCTCCTCTTCCTCTACTGAGACTTCAGAAAGCAGTAGT
GAGAGTGAGAGTAACAATAAAGAAAAAAAAATACAAAGGAAGAAAAGAAAGAAAAACAAGTGTTCAGGGCATAACAACAGTGATTCTGAA
GAGAAGGACAAGTCTAAGAAGAGAAAGCTTCATGAAGAACTTTCTAGCAGTCACCATAACCGGGAAAAAGCCAAGGAAAAGCCCAGGTTC
TTAAAACACGAGAGTTCTAGGGAGGACAGCAAATGGAGCCATTCTGATTCTGACAAAAAGTCCAGAACCCATAAACATAGCCCAGAGAAG
AGAGGCTCTGAAAGAAAGGAGGGGAGCAGCAGAAGCCACGGCAGGGAGGAAAGGAGCCGGAGAAGCCGGAGCAGAAGTCCTGGTAGTTAC
AAGCAAAGGGAGACAAGGAAACGGGCACAGCGAAATCCTGGTGAAGAGCAAAGCAGAAGAAATGACAGCAGAAGCCATGGCACAGACTTG
TATAGAGGAGAAAAAATGTACAGAGAGCACCCAGGAGGTACACATACTAAAGTGACACAAAGAGAATGAAGCAGAAGTAGAGAAGAAAGA
CTGTATGTGACAATTACCTGGGAATAAAAATATCTCCACTTTTTTATTGAATACCTTTAGCAAGGGGTAAATTATGTACTGTTGTCTTTC
TAATAAAAAAGCTCAATTTTAATTTTTCATCTCTAGACTGTCAATTCAAGTACAAAACTACATGAGTACTATAAGAATGAATTTTGCAAA
TATTTGTAAGTAAGCTATTTTGGGGCTGTGGAAATATTTTCTGTTGGTAACTGTTTCTTGTTCCCCATACCAGATAAAAACCGCATATAA
CTCTGTGACATTTTCTTTGTTCTGAAACATCATTAAAAGAATGACAGTACATTGAATGGGTATAATTTACTTTTTTCAATTCAAATTTGT
TATTCTAGGATTTGAATTTGCTTGAAGTGAATTGTAATAATTATTCAAATTCATTAGTATAAATTAAGGATTAATAAATCTTTAAGACTT
TTAA

>2763_2763_9_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000428334_CIR1_chr2_175252507_ENST00000342016_length(amino acids)=615AA_BP=189
MANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPS
HSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIG
SGRAIPIKQVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMGDERVKNGLNFMYEAPPGAKKENKEKEETEGETEYKFEWQKGAPRE
KYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGSGPSMHPSELIAEMRNSGFALKRNVLGRNLTANDP
SQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNK
EKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKE
GSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTHTKVTQRE

--------------------------------------------------------------
>2763_2763_10_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000428334_CIR1_chr2_175252507_ENST00000362053_length(transcript)=2242nt_BP=588nt
GTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCT
GCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATAC
GGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCAGAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTGCAAG
TCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTCCGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGGGAGT
TTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAGCACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACACGCCC
ACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCTGTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCTGGAG
AGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCCAATTAAACAGGTATGGATGGCAGAACAGAAAATATCATATGATAAGAAGAAA
CAAGAAGAATTGATGCAGCAATATCTTAAAGAACAAGAATCATATGATAATAGATTGCTTATGGGAGATGAACGTGTAAAGAATGGCCTT
AATTTCATGTATGAAGCCCCACCAGGAGCTAAAAAAGAAAACAAAGAGAAAGAAGAAACAGAAGGAGAGACCGAATACAAATTTGAATGG
CAGAAAGGAGCCCCACGAGAAAAATATGCCAAAGATGACATGAACATCAGAGATCAGCCCTTTGGTATTCAGGTTCGAAATGTGAGGTGC
ATTAAATGTCACAAATGGGGTCATGTCAACACAGATCGAGAATGTCCTTTGTTTGGTCTTTCTGGAATCAATGCAAGTTCGGTTCCCACT
GATGGCTCAGATGCTGTGTTACAAATTGAAGGTTTCTGGGCCATCGATGCACCCCTCGGAGCTAATAGCGGAGATGAGAAACAGTGGGTT
TGCACTGAAACGAAATGTACTGGGGAGAAACTTGACCGCAAATGATCCATCACAGGAGTATGTTGCAAGTGAGGGTGAAGAAGATCCAGA
AGTTGAATTTTTAAAGTCACTAACAACCAAACAAAAACAGAAACTTCTCAGGAAATTAGATCGACTGGAGAAGAAAAAAAAGAAAAAAGA
TAGAAAAAAGAAAAAGTTTCAGAAGAGCAGAAGTAAACACAAAAAACATAAGTCCTCTTCTTCCTCATCTTCCTCCTCCTCCTCCTCTTC
CTCTACTGAGACTTCAGAAAGCAGTAGTGAGAGTGAGAGTAACAATAAAGAAAAAAAAATACAAAGGAAGAAAAGAAAGAAAAACAAGTG
TTCAGGGCATAACAACAGTGATTCTGAAGAGAAGGACAAGTCTAAGAAGAGAAAGCTTCATGAAGAACTTTCTAGCAGTCACCATAACCG
GGAAAAAGCCAAGGAAAAGCCCAGGTTCTTAAAACACGAGAGTTCTAGGGAGGACAGCAAATGGAGCCATTCTGATTCTGACAAAAAGTC
CAGAACCCATAAACATAGCCCAGAGAAGAGAGGCTCTGAAAGAAAGGAGGGGAGCAGCAGAAGCCACGGCAGGGAGGAAAGGAGCCGGAG
AAGCCGGAGCAGAAGTCCTGGTAGTTACAAGCAAAGGGAGACAAGGAAACGGGCACAGCGAAATCCTGGTGAAGAGCAAAGCAGAAGAAA
TGACAGCAGAAGCCATGGCACAGACTTGTATAGAGGAGAAAAAATGTACAGAGAGCACCCAGGAGGTACACATACTAAAGTGACACAAAG
AGAATGAAGCAGAAGTAGAGAAGAAAGACTGTATGTGACAATTACCTGGGAATAAAAATATCTCCACTTTTTTATTGAATACCTTTAGCA
AGGGGTAAATTATGTACTGTTGTCTTTCTAATAAAAAAGCTCAATTTTAATTTTTCATCTCTAGACTGTCAATTCAAGTACAAAACTACA
TGAGTACTATAAGAATGAATTTTGCAAATATTTGTAAGTAAGCTATTTTGGGGCTGTGGAAATATTTTCTGTTGGTAACTGTTTCTTGTT
CCCCATACCAGATAAAAACCGCATATAACTCTGTGACATTTTCTTTGTTCTGAAACATCATTAAAAGAATGACAGTACATTG

>2763_2763_10_AGAP1-CIR1_AGAP1_chr2_236715975_ENST00000428334_CIR1_chr2_175252507_ENST00000362053_length(amino acids)=367AA_BP=189
MANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPS
HSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIG
SGRAIPIKQVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMGDERVKNGLNFMYEAPPGAKKENKEKEETEGETEYKFEWQKGAPRE
KYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGSDAVLQIEGFWAIDAPLGANSGDEKQWVCTETKCT
GEKLDRK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for AGAP1-CIR1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneCIR1chr2:236715975chr2:175252507ENST00000342016010204_23224.0451.0RP9
TgeneCIR1chr2:236715975chr2:175252507ENST00000362053011204_23224.0496.3333333333333RP9


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneCIR1chr2:236715975chr2:175252507ENST000003420160101_12124.0451.0RBPJ
TgeneCIR1chr2:236715975chr2:175252507ENST000003620530111_12124.0496.3333333333333RBPJ


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AGAP1-CIR1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AGAP1-CIR1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneAGAP1C0004352Autistic Disorder1CTD_human