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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:AGAP3-TG (FusionGDB2 ID:HG116988TG7038)

Fusion Gene Summary for AGAP3-TG

check button Fusion gene summary
Fusion gene informationFusion gene name: AGAP3-TG
Fusion gene ID: hg116988tg7038
HgeneTgene
Gene symbol

AGAP3

TG

Gene ID

116988

7038

Gene nameArfGAP with GTPase domain, ankyrin repeat and PH domain 3thyroglobulin
SynonymsAGAP-3|CENTG3|CRAG|MRIP-1|cnt-g3AITD3|TGN
Cytomap('AGAP3')('TG')

7q36.1

8q24.22

Type of geneprotein-codingprotein-coding
Descriptionarf-GAP with GTPase, ANK repeat and PH domain-containing protein 3CRAM-associated GTPaseCRMP (collapsin response mediator protein) associatedMR1-interacting proteincentaurin-gamma-3thyroglobulin
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000397238, ENST00000473312, 
ENST00000479901, ENST00000335367, 
ENST00000463381, ENST00000476375, 
Fusion gene scores* DoF score15 X 6 X 10=90027 X 26 X 8=5616
# samples 1429
** MAII scorelog2(14/900*10)=-2.68449817427207
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(29/5616*10)=-4.27541813028963
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AGAP3 [Title/Abstract] AND TG [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAGAP3(150784159)-TG(133948001), # samples:2
Anticipated loss of major functional domain due to fusion event.AGAP3-TG seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
AGAP3-TG seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
AGAP3-TG seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
AGAP3-TG seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
AGAP3-TG seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across AGAP3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across TG (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A1F0-01AAGAP3chr7

150784159

-TGchr8

133948001

+
ChimerDB4BRCATCGA-BH-A1F0-01AAGAP3chr7

150784159

+TGchr8

133948001

+
ChimerDB4BRCATCGA-BH-A1F0-01AAGAP3chr7

150784159

+TGchr8

133961021

+


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Fusion Gene ORF analysis for AGAP3-TG

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000397238ENST00000519543AGAP3chr7

150784159

+TGchr8

133948001

+
5CDS-intronENST00000397238ENST00000519543AGAP3chr7

150784159

+TGchr8

133961021

+
5CDS-intronENST00000397238ENST00000522523AGAP3chr7

150784159

+TGchr8

133948001

+
5CDS-intronENST00000397238ENST00000522523AGAP3chr7

150784159

+TGchr8

133961021

+
5CDS-intronENST00000473312ENST00000519543AGAP3chr7

150784159

+TGchr8

133948001

+
5CDS-intronENST00000473312ENST00000519543AGAP3chr7

150784159

+TGchr8

133961021

+
5CDS-intronENST00000473312ENST00000522523AGAP3chr7

150784159

+TGchr8

133948001

+
5CDS-intronENST00000473312ENST00000522523AGAP3chr7

150784159

+TGchr8

133961021

+
5CDS-intronENST00000479901ENST00000519543AGAP3chr7

150784159

+TGchr8

133948001

+
5CDS-intronENST00000479901ENST00000519543AGAP3chr7

150784159

+TGchr8

133961021

+
5CDS-intronENST00000479901ENST00000522523AGAP3chr7

150784159

+TGchr8

133948001

+
5CDS-intronENST00000479901ENST00000522523AGAP3chr7

150784159

+TGchr8

133961021

+
Frame-shiftENST00000397238ENST00000220616AGAP3chr7

150784159

+TGchr8

133948001

+
Frame-shiftENST00000397238ENST00000377869AGAP3chr7

150784159

+TGchr8

133948001

+
Frame-shiftENST00000397238ENST00000542445AGAP3chr7

150784159

+TGchr8

133948001

+
Frame-shiftENST00000473312ENST00000220616AGAP3chr7

150784159

+TGchr8

133948001

+
Frame-shiftENST00000473312ENST00000377869AGAP3chr7

150784159

+TGchr8

133948001

+
Frame-shiftENST00000473312ENST00000542445AGAP3chr7

150784159

+TGchr8

133948001

+
Frame-shiftENST00000479901ENST00000220616AGAP3chr7

150784159

+TGchr8

133948001

+
Frame-shiftENST00000479901ENST00000377869AGAP3chr7

150784159

+TGchr8

133948001

+
Frame-shiftENST00000479901ENST00000542445AGAP3chr7

150784159

+TGchr8

133948001

+
In-frameENST00000397238ENST00000220616AGAP3chr7

150784159

+TGchr8

133961021

+
In-frameENST00000397238ENST00000377869AGAP3chr7

150784159

+TGchr8

133961021

+
In-frameENST00000397238ENST00000542445AGAP3chr7

150784159

+TGchr8

133961021

+
In-frameENST00000473312ENST00000220616AGAP3chr7

150784159

+TGchr8

133961021

+
In-frameENST00000473312ENST00000377869AGAP3chr7

150784159

+TGchr8

133961021

+
In-frameENST00000473312ENST00000542445AGAP3chr7

150784159

+TGchr8

133961021

+
In-frameENST00000479901ENST00000220616AGAP3chr7

150784159

+TGchr8

133961021

+
In-frameENST00000479901ENST00000377869AGAP3chr7

150784159

+TGchr8

133961021

+
In-frameENST00000479901ENST00000542445AGAP3chr7

150784159

+TGchr8

133961021

+
intron-3CDSENST00000335367ENST00000220616AGAP3chr7

150784159

+TGchr8

133948001

+
intron-3CDSENST00000335367ENST00000220616AGAP3chr7

150784159

+TGchr8

133961021

+
intron-3CDSENST00000335367ENST00000377869AGAP3chr7

150784159

+TGchr8

133948001

+
intron-3CDSENST00000335367ENST00000377869AGAP3chr7

150784159

+TGchr8

133961021

+
intron-3CDSENST00000335367ENST00000542445AGAP3chr7

150784159

+TGchr8

133948001

+
intron-3CDSENST00000335367ENST00000542445AGAP3chr7

150784159

+TGchr8

133961021

+
intron-3CDSENST00000463381ENST00000220616AGAP3chr7

150784159

+TGchr8

133948001

+
intron-3CDSENST00000463381ENST00000220616AGAP3chr7

150784159

+TGchr8

133961021

+
intron-3CDSENST00000463381ENST00000377869AGAP3chr7

150784159

+TGchr8

133948001

+
intron-3CDSENST00000463381ENST00000377869AGAP3chr7

150784159

+TGchr8

133961021

+
intron-3CDSENST00000463381ENST00000542445AGAP3chr7

150784159

+TGchr8

133948001

+
intron-3CDSENST00000463381ENST00000542445AGAP3chr7

150784159

+TGchr8

133961021

+
intron-3CDSENST00000476375ENST00000220616AGAP3chr7

150784159

+TGchr8

133948001

+
intron-3CDSENST00000476375ENST00000220616AGAP3chr7

150784159

+TGchr8

133961021

+
intron-3CDSENST00000476375ENST00000377869AGAP3chr7

150784159

+TGchr8

133948001

+
intron-3CDSENST00000476375ENST00000377869AGAP3chr7

150784159

+TGchr8

133961021

+
intron-3CDSENST00000476375ENST00000542445AGAP3chr7

150784159

+TGchr8

133948001

+
intron-3CDSENST00000476375ENST00000542445AGAP3chr7

150784159

+TGchr8

133961021

+
intron-intronENST00000335367ENST00000519543AGAP3chr7

150784159

+TGchr8

133948001

+
intron-intronENST00000335367ENST00000519543AGAP3chr7

150784159

+TGchr8

133961021

+
intron-intronENST00000335367ENST00000522523AGAP3chr7

150784159

+TGchr8

133948001

+
intron-intronENST00000335367ENST00000522523AGAP3chr7

150784159

+TGchr8

133961021

+
intron-intronENST00000463381ENST00000519543AGAP3chr7

150784159

+TGchr8

133948001

+
intron-intronENST00000463381ENST00000519543AGAP3chr7

150784159

+TGchr8

133961021

+
intron-intronENST00000463381ENST00000522523AGAP3chr7

150784159

+TGchr8

133948001

+
intron-intronENST00000463381ENST00000522523AGAP3chr7

150784159

+TGchr8

133961021

+
intron-intronENST00000476375ENST00000519543AGAP3chr7

150784159

+TGchr8

133948001

+
intron-intronENST00000476375ENST00000519543AGAP3chr7

150784159

+TGchr8

133961021

+
intron-intronENST00000476375ENST00000522523AGAP3chr7

150784159

+TGchr8

133948001

+
intron-intronENST00000476375ENST00000522523AGAP3chr7

150784159

+TGchr8

133961021

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000473312AGAP3chr7150784159+ENST00000377869TGchr8133961021+3510331034041134
ENST00000473312AGAP3chr7150784159+ENST00000220616TGchr8133961021+3508331034041134
ENST00000473312AGAP3chr7150784159+ENST00000542445TGchr8133961021+3438331034041134
ENST00000479901AGAP3chr7150784159+ENST00000377869TGchr8133961021+3510331034041134
ENST00000479901AGAP3chr7150784159+ENST00000220616TGchr8133961021+3508331034041134
ENST00000479901AGAP3chr7150784159+ENST00000542445TGchr8133961021+3438331034041134
ENST00000397238AGAP3chr7150784159+ENST00000377869TGchr8133961021+3510331034041134
ENST00000397238AGAP3chr7150784159+ENST00000220616TGchr8133961021+3508331034041134
ENST00000397238AGAP3chr7150784159+ENST00000542445TGchr8133961021+3438331034041134

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000473312ENST00000377869AGAP3chr7150784159+TGchr8133961021+0.0030327950.99696726
ENST00000473312ENST00000220616AGAP3chr7150784159+TGchr8133961021+0.0030088870.99699104
ENST00000473312ENST00000542445AGAP3chr7150784159+TGchr8133961021+0.0033043270.99669564
ENST00000479901ENST00000377869AGAP3chr7150784159+TGchr8133961021+0.0030327950.99696726
ENST00000479901ENST00000220616AGAP3chr7150784159+TGchr8133961021+0.0030088870.99699104
ENST00000479901ENST00000542445AGAP3chr7150784159+TGchr8133961021+0.0033043270.99669564
ENST00000397238ENST00000377869AGAP3chr7150784159+TGchr8133961021+0.0030327950.99696726
ENST00000397238ENST00000220616AGAP3chr7150784159+TGchr8133961021+0.0030088870.99699104
ENST00000397238ENST00000542445AGAP3chr7150784159+TGchr8133961021+0.0033043270.99669564

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Fusion Genomic Features for AGAP3-TG


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
AGAP3chr7150784159+TGchr8133961020+7.26E-070.9999993
AGAP3chr7150784159+TGchr8133948000+1.85E-091
AGAP3chr7150784159+TGchr8133961020+7.26E-070.9999993
AGAP3chr7150784159+TGchr8133948000+1.85E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for AGAP3-TG


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:150784159/chr8:133948001)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAGAP3chr7:150784159chr8:133961021ENST00000397238+11898_105110912.0Nucleotide bindingGTP
TgeneTGchr7:150784159chr8:133961021ENST0000022061625482188_276817442769.0RegionCholinesterase-like (ChEL)
TgeneTGchr7:150784159chr8:133961021ENST0000037786924472188_276816872712.0RegionCholinesterase-like (ChEL)
TgeneTGchr7:150784159chr8:133961021ENST0000022061625481893_199517442769.0RepeatType IIIA
TgeneTGchr7:150784159chr8:133961021ENST0000022061625481996_212917442769.0RepeatType IIIB
TgeneTGchr7:150784159chr8:133961021ENST0000022061625482130_218717442769.0RepeatType IIIA
TgeneTGchr7:150784159chr8:133961021ENST0000037786924471724_189216872712.0RepeatType IIIB
TgeneTGchr7:150784159chr8:133961021ENST0000037786924471893_199516872712.0RepeatType IIIA
TgeneTGchr7:150784159chr8:133961021ENST0000037786924471996_212916872712.0RepeatType IIIB
TgeneTGchr7:150784159chr8:133961021ENST0000037786924472130_218716872712.0RepeatType IIIA

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAGAP3chr7:150784159chr8:133961021ENST00000397238+118367_605110912.0DomainPH
HgeneAGAP3chr7:150784159chr8:133961021ENST00000397238+118626_746110912.0DomainArf-GAP
HgeneAGAP3chr7:150784159chr8:133961021ENST00000397238+118142_146110912.0Nucleotide bindingGTP
HgeneAGAP3chr7:150784159chr8:133961021ENST00000397238+118198_201110912.0Nucleotide bindingGTP
HgeneAGAP3chr7:150784159chr8:133961021ENST00000397238+11884_375110912.0RegionNote=Small GTPase-like
HgeneAGAP3chr7:150784159chr8:133961021ENST00000397238+118748_777110912.0RepeatNote=ANK 1
HgeneAGAP3chr7:150784159chr8:133961021ENST00000397238+118785_814110912.0RepeatNote=ANK 2
HgeneAGAP3chr7:150784159chr8:133961021ENST00000397238+118818_847110912.0RepeatNote=ANK 3
HgeneAGAP3chr7:150784159chr8:133961021ENST00000397238+118641_664110912.0Zinc fingerC4-type
TgeneTGchr7:150784159chr8:133961021ENST0000022061625481074_114517442769.0DomainThyroglobulin type-1 9
TgeneTGchr7:150784159chr8:133961021ENST0000022061625481146_121017442769.0DomainThyroglobulin type-1 10
TgeneTGchr7:150784159chr8:133961021ENST0000022061625481511_156517442769.0DomainThyroglobulin type-1 11
TgeneTGchr7:150784159chr8:133961021ENST000002206162548161_29717442769.0DomainThyroglobulin type-1 3
TgeneTGchr7:150784159chr8:133961021ENST000002206162548298_35817442769.0DomainThyroglobulin type-1 4
TgeneTGchr7:150784159chr8:133961021ENST00000220616254831_9217442769.0DomainThyroglobulin type-1 1
TgeneTGchr7:150784159chr8:133961021ENST000002206162548605_65817442769.0DomainThyroglobulin type-1 5
TgeneTGchr7:150784159chr8:133961021ENST000002206162548659_72617442769.0DomainThyroglobulin type-1 6
TgeneTGchr7:150784159chr8:133961021ENST000002206162548727_92117442769.0DomainThyroglobulin type-1 7
TgeneTGchr7:150784159chr8:133961021ENST000002206162548922_107317442769.0DomainThyroglobulin type-1 8
TgeneTGchr7:150784159chr8:133961021ENST00000220616254893_16017442769.0DomainThyroglobulin type-1 2
TgeneTGchr7:150784159chr8:133961021ENST0000037786924471074_114516872712.0DomainThyroglobulin type-1 9
TgeneTGchr7:150784159chr8:133961021ENST0000037786924471146_121016872712.0DomainThyroglobulin type-1 10
TgeneTGchr7:150784159chr8:133961021ENST0000037786924471511_156516872712.0DomainThyroglobulin type-1 11
TgeneTGchr7:150784159chr8:133961021ENST000003778692447161_29716872712.0DomainThyroglobulin type-1 3
TgeneTGchr7:150784159chr8:133961021ENST000003778692447298_35816872712.0DomainThyroglobulin type-1 4
TgeneTGchr7:150784159chr8:133961021ENST00000377869244731_9216872712.0DomainThyroglobulin type-1 1
TgeneTGchr7:150784159chr8:133961021ENST000003778692447605_65816872712.0DomainThyroglobulin type-1 5
TgeneTGchr7:150784159chr8:133961021ENST000003778692447659_72616872712.0DomainThyroglobulin type-1 6
TgeneTGchr7:150784159chr8:133961021ENST000003778692447727_92116872712.0DomainThyroglobulin type-1 7
TgeneTGchr7:150784159chr8:133961021ENST000003778692447922_107316872712.0DomainThyroglobulin type-1 8
TgeneTGchr7:150784159chr8:133961021ENST00000377869244793_16016872712.0DomainThyroglobulin type-1 2
TgeneTGchr7:150784159chr8:133961021ENST0000022061625481456_146917442769.0RepeatType II
TgeneTGchr7:150784159chr8:133961021ENST0000022061625481470_148617442769.0RepeatType II
TgeneTGchr7:150784159chr8:133961021ENST0000022061625481487_150317442769.0RepeatType II
TgeneTGchr7:150784159chr8:133961021ENST0000022061625481603_172317442769.0RepeatType IIIA
TgeneTGchr7:150784159chr8:133961021ENST0000022061625481724_189217442769.0RepeatType IIIB
TgeneTGchr7:150784159chr8:133961021ENST0000037786924471456_146916872712.0RepeatType II
TgeneTGchr7:150784159chr8:133961021ENST0000037786924471470_148616872712.0RepeatType II
TgeneTGchr7:150784159chr8:133961021ENST0000037786924471487_150316872712.0RepeatType II
TgeneTGchr7:150784159chr8:133961021ENST0000037786924471603_172316872712.0RepeatType IIIA


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Fusion Gene Sequence for AGAP3-TG


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>2828_2828_1_AGAP3-TG_AGAP3_chr7_150784159_ENST00000397238_TG_chr8_133961021_ENST00000220616_length(transcript)=3508nt_BP=331nt
ATGAACTTCCAGGCGGGCGGGGGGCAGAGCCCGCAGCAGCAGCAGAGCCTGGCGGCTCCGGGGGGCGGCGGCGCTGCCGCGCAGCAGCTC
GTCTGCGGCGGGCAGTTCGGCGGCGCGGGGCCCGGGGCCGGGGGCGGCGGCGGCCCCTCGCAGCAGCTGGCCGGCGGGCCCCCCCAGCAG
TTCGCGCTCTCCAACTCCGCGGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCCGTGCATCCCAATATCTACGCCATCTACGACCTGATC
GAGCGCATCGAGGATTTGGCGCTGCAGAACCAGATCCGGGAGCACGTCATCTCCATCGAGGGTGCCATCATCTGTGGGTTGCTGAGCTCA
CCCAGTGTCCTGCTTTGTAATGTCAAAGACTGGATGGATCCCTCTGAAGCCTGGGCTAATGCTACATGTCCTGGTGTGACATATGACCAG
GAGAGCCACCAGGTGATATTGCGTCTTGGAGACCAGGAGTTCATCAAGAGTCTGACACCCTTAGAAGGAACTCAAGACACCTTTACCAAT
TTTCAGCAGGTTTATCTCTGGAAAGATTCTGACATGGGGTCTCGGCCTGAGTCTATGGGATGTAGAAAAGACACAGTGCCAAGGCCAGCA
TCTCCAACAGAAGCAGGTTTGACAACAGAACTTTTCTCCCCTGTGGACCTCAACCAGGTCATTGTCAATGGAAATCAATCACTATCCAGC
CAGAAGCACTGGCTTTTCAAGCACCTGTTTTCAGCCCAGCAGGCAAACCTATGGTGCCTTTCTCGTTGTGTGCAGGAGCACTCTTTCTGT
CAGCTCGCAGAGATAACAGAGAGTGCATCCTTGTACTTCACCTGCACCCTCTACCCAGAGGCACAGGTGTGTGATGACATCATGGAGTCC
AATGCCCAGGGCTGCAGACTGATCCTGCCTCAGATGCCAAAGGCCCTGTTCCGGAAGAAAGTTATACTGGAAGATAAAGTGAAGAACTTT
TACACTCGCCTGCCGTTCCAAAAACTGATGGGGATATCCATTAGAAATAAAGTGCCCATGTCTGAAAAATCTATTTCTAATGGGTTCTTT
GAATGTGAACGACGGTGCGATGCGGACCCATGCTGCACTGGCTTTGGATTTCTAAATGTTTCCCAGTTAAAAGGAGGAGAGGTGACATGT
CTCACTCTGAACAGCTTGGGAATTCAGATGTGCAGTGAGGAGAATGGAGGAGCCTGGCGCATTTTGGACTGTGGCTCTCCTGACATTGAA
GTCCACACCTATCCCTTCGGATGGTACCAGAAGCCCATTGCTCAAAATAATGCTCCCAGTTTTTGCCCTTTGGTTGTTCTGCCTTCCCTC
ACAGAGAAAGTGTCTCTGGACTCGTGGCAGTCCCTGGCCCTCTCTTCAGTGGTTGTTGATCCATCCATTAGGCACTTTGATGTTGCCCAT
GTCAGCACTGCTGCCACCAGCAATTTCTCTGCTGTCCGAGACCTCTGTTTGTCGGAATGTTCCCAACATGAGGCCTGTCTCATCACCACT
CTGCAAACCCAACCTGGGGCTGTGAGATGTATGTTCTATGCTGATACTCAAAGCTGCACACATAGTCTGCAGGGTCAGAACTGCCGACTT
CTGCTTCGTGAAGAGGCCACCCACATCTACCGGAAGCCAGGAATCTCTCTGCTCAGCTATGAGGCATCTGTACCTTCTGTGCCCATTTCC
ACCCATGGCCGGCTGCTGGGCAGGTCCCAGGCCATCCAGGTGGGTACCTCATGGAAGCAAGTGGACCAGTTCCTTGGAGTTCCATATGCT
GCCCCGCCCCTGGCAGAGAGGCGCTTCCAGGCACCAGAGCCCTTGAACTGGACAGGCTCCTGGGATGCCAGCAAGCCAAGGGCCAGCTGC
TGGCAGCCAGGCACCAGAACATCCACGTCTCCTGGAGTCAGTGAAGATTGTTTGTATCTCAATGTGTTCATCCCTCAGAATGTGGCCCCT
AACGCGTCTGTGCTGGTGTTCTTCCACAACACCATGGACAGGGAGGAGAGTGAAGGATGGCCGGCTATCGACGGCTCCTTCTTGGCTGCT
GTTGGCAACCTCATCGTGGTCACTGCCAGCTACCGAGTGGGTGTCTTCGGCTTCCTGAGTTCTGGGTCCGGAGAGGTGAGTGGCAACTGG
GGGCTGCTGGACCAGGTGGCGGCTCTGACCTGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGGCAGCA
GACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGATGGGA
GGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATG
TCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTGGC
CCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAGAGGTC
GATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGT
AGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTAC
TCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTATAATC
GACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGGAGCTG
CTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAA
ATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCCCC
TGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAGCCGAC
TGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAG
TTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTGAGCTC
CCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATGCGGTG

>2828_2828_1_AGAP3-TG_AGAP3_chr7_150784159_ENST00000397238_TG_chr8_133961021_ENST00000220616_length(amino acids)=1134AA_BP=105
MNFQAGGGQSPQQQQSLAAPGGGGAAAQQLVCGGQFGGAGPGAGGGGGPSQQLAGGPPQQFALSNSAAIRAEIQRFESVHPNIYAIYDLI
ERIEDLALQNQIREHVISIEGAIICGLLSSPSVLLCNVKDWMDPSEAWANATCPGVTYDQESHQVILRLGDQEFIKSLTPLEGTQDTFTN
FQQVYLWKDSDMGSRPESMGCRKDTVPRPASPTEAGLTTELFSPVDLNQVIVNGNQSLSSQKHWLFKHLFSAQQANLWCLSRCVQEHSFC
QLAEITESASLYFTCTLYPEAQVCDDIMESNAQGCRLILPQMPKALFRKKVILEDKVKNFYTRLPFQKLMGISIRNKVPMSEKSISNGFF
ECERRCDADPCCTGFGFLNVSQLKGGEVTCLTLNSLGIQMCSEENGGAWRILDCGSPDIEVHTYPFGWYQKPIAQNNAPSFCPLVVLPSL
TEKVSLDSWQSLALSSVVVDPSIRHFDVAHVSTAATSNFSAVRDLCLSECSQHEACLITTLQTQPGAVRCMFYADTQSCTHSLQGQNCRL
LLREEATHIYRKPGISLLSYEASVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASC
WQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNW
GLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPM
SSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTS
SKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLEL
LADVQFALGLPFYPAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKAD
CSFWSKYISSLKTSADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>2828_2828_2_AGAP3-TG_AGAP3_chr7_150784159_ENST00000397238_TG_chr8_133961021_ENST00000377869_length(transcript)=3510nt_BP=331nt
ATGAACTTCCAGGCGGGCGGGGGGCAGAGCCCGCAGCAGCAGCAGAGCCTGGCGGCTCCGGGGGGCGGCGGCGCTGCCGCGCAGCAGCTC
GTCTGCGGCGGGCAGTTCGGCGGCGCGGGGCCCGGGGCCGGGGGCGGCGGCGGCCCCTCGCAGCAGCTGGCCGGCGGGCCCCCCCAGCAG
TTCGCGCTCTCCAACTCCGCGGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCCGTGCATCCCAATATCTACGCCATCTACGACCTGATC
GAGCGCATCGAGGATTTGGCGCTGCAGAACCAGATCCGGGAGCACGTCATCTCCATCGAGGGTGCCATCATCTGTGGGTTGCTGAGCTCA
CCCAGTGTCCTGCTTTGTAATGTCAAAGACTGGATGGATCCCTCTGAAGCCTGGGCTAATGCTACATGTCCTGGTGTGACATATGACCAG
GAGAGCCACCAGGTGATATTGCGTCTTGGAGACCAGGAGTTCATCAAGAGTCTGACACCCTTAGAAGGAACTCAAGACACCTTTACCAAT
TTTCAGCAGGTTTATCTCTGGAAAGATTCTGACATGGGGTCTCGGCCTGAGTCTATGGGATGTAGAAAAGACACAGTGCCAAGGCCAGCA
TCTCCAACAGAAGCAGGTTTGACAACAGAACTTTTCTCCCCTGTGGACCTCAACCAGGTCATTGTCAATGGAAATCAATCACTATCCAGC
CAGAAGCACTGGCTTTTCAAGCACCTGTTTTCAGCCCAGCAGGCAAACCTATGGTGCCTTTCTCGTTGTGTGCAGGAGCACTCTTTCTGT
CAGCTCGCAGAGATAACAGAGAGTGCATCCTTGTACTTCACCTGCACCCTCTACCCAGAGGCACAGGTGTGTGATGACATCATGGAGTCC
AATGCCCAGGGCTGCAGACTGATCCTGCCTCAGATGCCAAAGGCCCTGTTCCGGAAGAAAGTTATACTGGAAGATAAAGTGAAGAACTTT
TACACTCGCCTGCCGTTCCAAAAACTGATGGGGATATCCATTAGAAATAAAGTGCCCATGTCTGAAAAATCTATTTCTAATGGGTTCTTT
GAATGTGAACGACGGTGCGATGCGGACCCATGCTGCACTGGCTTTGGATTTCTAAATGTTTCCCAGTTAAAAGGAGGAGAGGTGACATGT
CTCACTCTGAACAGCTTGGGAATTCAGATGTGCAGTGAGGAGAATGGAGGAGCCTGGCGCATTTTGGACTGTGGCTCTCCTGACATTGAA
GTCCACACCTATCCCTTCGGATGGTACCAGAAGCCCATTGCTCAAAATAATGCTCCCAGTTTTTGCCCTTTGGTTGTTCTGCCTTCCCTC
ACAGAGAAAGTGTCTCTGGACTCGTGGCAGTCCCTGGCCCTCTCTTCAGTGGTTGTTGATCCATCCATTAGGCACTTTGATGTTGCCCAT
GTCAGCACTGCTGCCACCAGCAATTTCTCTGCTGTCCGAGACCTCTGTTTGTCGGAATGTTCCCAACATGAGGCCTGTCTCATCACCACT
CTGCAAACCCAACCTGGGGCTGTGAGATGTATGTTCTATGCTGATACTCAAAGCTGCACACATAGTCTGCAGGGTCAGAACTGCCGACTT
CTGCTTCGTGAAGAGGCCACCCACATCTACCGGAAGCCAGGAATCTCTCTGCTCAGCTATGAGGCATCTGTACCTTCTGTGCCCATTTCC
ACCCATGGCCGGCTGCTGGGCAGGTCCCAGGCCATCCAGGTGGGTACCTCATGGAAGCAAGTGGACCAGTTCCTTGGAGTTCCATATGCT
GCCCCGCCCCTGGCAGAGAGGCGCTTCCAGGCACCAGAGCCCTTGAACTGGACAGGCTCCTGGGATGCCAGCAAGCCAAGGGCCAGCTGC
TGGCAGCCAGGCACCAGAACATCCACGTCTCCTGGAGTCAGTGAAGATTGTTTGTATCTCAATGTGTTCATCCCTCAGAATGTGGCCCCT
AACGCGTCTGTGCTGGTGTTCTTCCACAACACCATGGACAGGGAGGAGAGTGAAGGATGGCCGGCTATCGACGGCTCCTTCTTGGCTGCT
GTTGGCAACCTCATCGTGGTCACTGCCAGCTACCGAGTGGGTGTCTTCGGCTTCCTGAGTTCTGGGTCCGGAGAGGTGAGTGGCAACTGG
GGGCTGCTGGACCAGGTGGCGGCTCTGACCTGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGGCAGCA
GACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGATGGGA
GGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATG
TCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTGGC
CCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAGAGGTC
GATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGT
AGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTAC
TCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTATAATC
GACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGGAGCTG
CTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAA
ATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCCCC
TGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAGCCGAC
TGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAG
TTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTGAGCTC
CCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATGCGGTGAA


>2828_2828_2_AGAP3-TG_AGAP3_chr7_150784159_ENST00000397238_TG_chr8_133961021_ENST00000377869_length(amino acids)=1134AA_BP=105
MNFQAGGGQSPQQQQSLAAPGGGGAAAQQLVCGGQFGGAGPGAGGGGGPSQQLAGGPPQQFALSNSAAIRAEIQRFESVHPNIYAIYDLI
ERIEDLALQNQIREHVISIEGAIICGLLSSPSVLLCNVKDWMDPSEAWANATCPGVTYDQESHQVILRLGDQEFIKSLTPLEGTQDTFTN
FQQVYLWKDSDMGSRPESMGCRKDTVPRPASPTEAGLTTELFSPVDLNQVIVNGNQSLSSQKHWLFKHLFSAQQANLWCLSRCVQEHSFC
QLAEITESASLYFTCTLYPEAQVCDDIMESNAQGCRLILPQMPKALFRKKVILEDKVKNFYTRLPFQKLMGISIRNKVPMSEKSISNGFF
ECERRCDADPCCTGFGFLNVSQLKGGEVTCLTLNSLGIQMCSEENGGAWRILDCGSPDIEVHTYPFGWYQKPIAQNNAPSFCPLVVLPSL
TEKVSLDSWQSLALSSVVVDPSIRHFDVAHVSTAATSNFSAVRDLCLSECSQHEACLITTLQTQPGAVRCMFYADTQSCTHSLQGQNCRL
LLREEATHIYRKPGISLLSYEASVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASC
WQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNW
GLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPM
SSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTS
SKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLEL
LADVQFALGLPFYPAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKAD
CSFWSKYISSLKTSADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>2828_2828_3_AGAP3-TG_AGAP3_chr7_150784159_ENST00000397238_TG_chr8_133961021_ENST00000542445_length(transcript)=3438nt_BP=331nt
ATGAACTTCCAGGCGGGCGGGGGGCAGAGCCCGCAGCAGCAGCAGAGCCTGGCGGCTCCGGGGGGCGGCGGCGCTGCCGCGCAGCAGCTC
GTCTGCGGCGGGCAGTTCGGCGGCGCGGGGCCCGGGGCCGGGGGCGGCGGCGGCCCCTCGCAGCAGCTGGCCGGCGGGCCCCCCCAGCAG
TTCGCGCTCTCCAACTCCGCGGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCCGTGCATCCCAATATCTACGCCATCTACGACCTGATC
GAGCGCATCGAGGATTTGGCGCTGCAGAACCAGATCCGGGAGCACGTCATCTCCATCGAGGGTGCCATCATCTGTGGGTTGCTGAGCTCA
CCCAGTGTCCTGCTTTGTAATGTCAAAGACTGGATGGATCCCTCTGAAGCCTGGGCTAATGCTACATGTCCTGGTGTGACATATGACCAG
GAGAGCCACCAGGTGATATTGCGTCTTGGAGACCAGGAGTTCATCAAGAGTCTGACACCCTTAGAAGGAACTCAAGACACCTTTACCAAT
TTTCAGCAGGTTTATCTCTGGAAAGATTCTGACATGGGGTCTCGGCCTGAGTCTATGGGATGTAGAAAAGACACAGTGCCAAGGCCAGCA
TCTCCAACAGAAGCAGGTTTGACAACAGAACTTTTCTCCCCTGTGGACCTCAACCAGGTCATTGTCAATGGAAATCAATCACTATCCAGC
CAGAAGCACTGGCTTTTCAAGCACCTGTTTTCAGCCCAGCAGGCAAACCTATGGTGCCTTTCTCGTTGTGTGCAGGAGCACTCTTTCTGT
CAGCTCGCAGAGATAACAGAGAGTGCATCCTTGTACTTCACCTGCACCCTCTACCCAGAGGCACAGGTGTGTGATGACATCATGGAGTCC
AATGCCCAGGGCTGCAGACTGATCCTGCCTCAGATGCCAAAGGCCCTGTTCCGGAAGAAAGTTATACTGGAAGATAAAGTGAAGAACTTT
TACACTCGCCTGCCGTTCCAAAAACTGATGGGGATATCCATTAGAAATAAAGTGCCCATGTCTGAAAAATCTATTTCTAATGGGTTCTTT
GAATGTGAACGACGGTGCGATGCGGACCCATGCTGCACTGGCTTTGGATTTCTAAATGTTTCCCAGTTAAAAGGAGGAGAGGTGACATGT
CTCACTCTGAACAGCTTGGGAATTCAGATGTGCAGTGAGGAGAATGGAGGAGCCTGGCGCATTTTGGACTGTGGCTCTCCTGACATTGAA
GTCCACACCTATCCCTTCGGATGGTACCAGAAGCCCATTGCTCAAAATAATGCTCCCAGTTTTTGCCCTTTGGTTGTTCTGCCTTCCCTC
ACAGAGAAAGTGTCTCTGGACTCGTGGCAGTCCCTGGCCCTCTCTTCAGTGGTTGTTGATCCATCCATTAGGCACTTTGATGTTGCCCAT
GTCAGCACTGCTGCCACCAGCAATTTCTCTGCTGTCCGAGACCTCTGTTTGTCGGAATGTTCCCAACATGAGGCCTGTCTCATCACCACT
CTGCAAACCCAACCTGGGGCTGTGAGATGTATGTTCTATGCTGATACTCAAAGCTGCACACATAGTCTGCAGGGTCAGAACTGCCGACTT
CTGCTTCGTGAAGAGGCCACCCACATCTACCGGAAGCCAGGAATCTCTCTGCTCAGCTATGAGGCATCTGTACCTTCTGTGCCCATTTCC
ACCCATGGCCGGCTGCTGGGCAGGTCCCAGGCCATCCAGGTGGGTACCTCATGGAAGCAAGTGGACCAGTTCCTTGGAGTTCCATATGCT
GCCCCGCCCCTGGCAGAGAGGCGCTTCCAGGCACCAGAGCCCTTGAACTGGACAGGCTCCTGGGATGCCAGCAAGCCAAGGGCCAGCTGC
TGGCAGCCAGGCACCAGAACATCCACGTCTCCTGGAGTCAGTGAAGATTGTTTGTATCTCAATGTGTTCATCCCTCAGAATGTGGCCCCT
AACGCGTCTGTGCTGGTGTTCTTCCACAACACCATGGACAGGGAGGAGAGTGAAGGATGGCCGGCTATCGACGGCTCCTTCTTGGCTGCT
GTTGGCAACCTCATCGTGGTCACTGCCAGCTACCGAGTGGGTGTCTTCGGCTTCCTGAGTTCTGGGTCCGGAGAGGTGAGTGGCAACTGG
GGGCTGCTGGACCAGGTGGCGGCTCTGACCTGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGGCAGCA
GACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGATGGGA
GGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATG
TCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTGGC
CCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAGAGGTC
GATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGT
AGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTAC
TCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTATAATC
GACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGGAGCTG
CTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAA
ATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCCCC
TGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAGCCGAC
TGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAG
TTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTGAGCTC
CCCAAAAACCTCACCCGA

>2828_2828_3_AGAP3-TG_AGAP3_chr7_150784159_ENST00000397238_TG_chr8_133961021_ENST00000542445_length(amino acids)=1134AA_BP=105
MNFQAGGGQSPQQQQSLAAPGGGGAAAQQLVCGGQFGGAGPGAGGGGGPSQQLAGGPPQQFALSNSAAIRAEIQRFESVHPNIYAIYDLI
ERIEDLALQNQIREHVISIEGAIICGLLSSPSVLLCNVKDWMDPSEAWANATCPGVTYDQESHQVILRLGDQEFIKSLTPLEGTQDTFTN
FQQVYLWKDSDMGSRPESMGCRKDTVPRPASPTEAGLTTELFSPVDLNQVIVNGNQSLSSQKHWLFKHLFSAQQANLWCLSRCVQEHSFC
QLAEITESASLYFTCTLYPEAQVCDDIMESNAQGCRLILPQMPKALFRKKVILEDKVKNFYTRLPFQKLMGISIRNKVPMSEKSISNGFF
ECERRCDADPCCTGFGFLNVSQLKGGEVTCLTLNSLGIQMCSEENGGAWRILDCGSPDIEVHTYPFGWYQKPIAQNNAPSFCPLVVLPSL
TEKVSLDSWQSLALSSVVVDPSIRHFDVAHVSTAATSNFSAVRDLCLSECSQHEACLITTLQTQPGAVRCMFYADTQSCTHSLQGQNCRL
LLREEATHIYRKPGISLLSYEASVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASC
WQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNW
GLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPM
SSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTS
SKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLEL
LADVQFALGLPFYPAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKAD
CSFWSKYISSLKTSADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>2828_2828_4_AGAP3-TG_AGAP3_chr7_150784159_ENST00000473312_TG_chr8_133961021_ENST00000220616_length(transcript)=3508nt_BP=331nt
ATGAACTTCCAGGCGGGCGGGGGGCAGAGCCCGCAGCAGCAGCAGAGCCTGGCGGCTCCGGGGGGCGGCGGCGCTGCCGCGCAGCAGCTC
GTCTGCGGCGGGCAGTTCGGCGGCGCGGGGCCCGGGGCCGGGGGCGGCGGCGGCCCCTCGCAGCAGCTGGCCGGCGGGCCCCCCCAGCAG
TTCGCGCTCTCCAACTCCGCGGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCCGTGCATCCCAATATCTACGCCATCTACGACCTGATC
GAGCGCATCGAGGATTTGGCGCTGCAGAACCAGATCCGGGAGCACGTCATCTCCATCGAGGGTGCCATCATCTGTGGGTTGCTGAGCTCA
CCCAGTGTCCTGCTTTGTAATGTCAAAGACTGGATGGATCCCTCTGAAGCCTGGGCTAATGCTACATGTCCTGGTGTGACATATGACCAG
GAGAGCCACCAGGTGATATTGCGTCTTGGAGACCAGGAGTTCATCAAGAGTCTGACACCCTTAGAAGGAACTCAAGACACCTTTACCAAT
TTTCAGCAGGTTTATCTCTGGAAAGATTCTGACATGGGGTCTCGGCCTGAGTCTATGGGATGTAGAAAAGACACAGTGCCAAGGCCAGCA
TCTCCAACAGAAGCAGGTTTGACAACAGAACTTTTCTCCCCTGTGGACCTCAACCAGGTCATTGTCAATGGAAATCAATCACTATCCAGC
CAGAAGCACTGGCTTTTCAAGCACCTGTTTTCAGCCCAGCAGGCAAACCTATGGTGCCTTTCTCGTTGTGTGCAGGAGCACTCTTTCTGT
CAGCTCGCAGAGATAACAGAGAGTGCATCCTTGTACTTCACCTGCACCCTCTACCCAGAGGCACAGGTGTGTGATGACATCATGGAGTCC
AATGCCCAGGGCTGCAGACTGATCCTGCCTCAGATGCCAAAGGCCCTGTTCCGGAAGAAAGTTATACTGGAAGATAAAGTGAAGAACTTT
TACACTCGCCTGCCGTTCCAAAAACTGATGGGGATATCCATTAGAAATAAAGTGCCCATGTCTGAAAAATCTATTTCTAATGGGTTCTTT
GAATGTGAACGACGGTGCGATGCGGACCCATGCTGCACTGGCTTTGGATTTCTAAATGTTTCCCAGTTAAAAGGAGGAGAGGTGACATGT
CTCACTCTGAACAGCTTGGGAATTCAGATGTGCAGTGAGGAGAATGGAGGAGCCTGGCGCATTTTGGACTGTGGCTCTCCTGACATTGAA
GTCCACACCTATCCCTTCGGATGGTACCAGAAGCCCATTGCTCAAAATAATGCTCCCAGTTTTTGCCCTTTGGTTGTTCTGCCTTCCCTC
ACAGAGAAAGTGTCTCTGGACTCGTGGCAGTCCCTGGCCCTCTCTTCAGTGGTTGTTGATCCATCCATTAGGCACTTTGATGTTGCCCAT
GTCAGCACTGCTGCCACCAGCAATTTCTCTGCTGTCCGAGACCTCTGTTTGTCGGAATGTTCCCAACATGAGGCCTGTCTCATCACCACT
CTGCAAACCCAACCTGGGGCTGTGAGATGTATGTTCTATGCTGATACTCAAAGCTGCACACATAGTCTGCAGGGTCAGAACTGCCGACTT
CTGCTTCGTGAAGAGGCCACCCACATCTACCGGAAGCCAGGAATCTCTCTGCTCAGCTATGAGGCATCTGTACCTTCTGTGCCCATTTCC
ACCCATGGCCGGCTGCTGGGCAGGTCCCAGGCCATCCAGGTGGGTACCTCATGGAAGCAAGTGGACCAGTTCCTTGGAGTTCCATATGCT
GCCCCGCCCCTGGCAGAGAGGCGCTTCCAGGCACCAGAGCCCTTGAACTGGACAGGCTCCTGGGATGCCAGCAAGCCAAGGGCCAGCTGC
TGGCAGCCAGGCACCAGAACATCCACGTCTCCTGGAGTCAGTGAAGATTGTTTGTATCTCAATGTGTTCATCCCTCAGAATGTGGCCCCT
AACGCGTCTGTGCTGGTGTTCTTCCACAACACCATGGACAGGGAGGAGAGTGAAGGATGGCCGGCTATCGACGGCTCCTTCTTGGCTGCT
GTTGGCAACCTCATCGTGGTCACTGCCAGCTACCGAGTGGGTGTCTTCGGCTTCCTGAGTTCTGGGTCCGGAGAGGTGAGTGGCAACTGG
GGGCTGCTGGACCAGGTGGCGGCTCTGACCTGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGGCAGCA
GACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGATGGGA
GGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATG
TCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTGGC
CCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAGAGGTC
GATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGT
AGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTAC
TCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTATAATC
GACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGGAGCTG
CTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAA
ATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCCCC
TGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAGCCGAC
TGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAG
TTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTGAGCTC
CCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATGCGGTG

>2828_2828_4_AGAP3-TG_AGAP3_chr7_150784159_ENST00000473312_TG_chr8_133961021_ENST00000220616_length(amino acids)=1134AA_BP=105
MNFQAGGGQSPQQQQSLAAPGGGGAAAQQLVCGGQFGGAGPGAGGGGGPSQQLAGGPPQQFALSNSAAIRAEIQRFESVHPNIYAIYDLI
ERIEDLALQNQIREHVISIEGAIICGLLSSPSVLLCNVKDWMDPSEAWANATCPGVTYDQESHQVILRLGDQEFIKSLTPLEGTQDTFTN
FQQVYLWKDSDMGSRPESMGCRKDTVPRPASPTEAGLTTELFSPVDLNQVIVNGNQSLSSQKHWLFKHLFSAQQANLWCLSRCVQEHSFC
QLAEITESASLYFTCTLYPEAQVCDDIMESNAQGCRLILPQMPKALFRKKVILEDKVKNFYTRLPFQKLMGISIRNKVPMSEKSISNGFF
ECERRCDADPCCTGFGFLNVSQLKGGEVTCLTLNSLGIQMCSEENGGAWRILDCGSPDIEVHTYPFGWYQKPIAQNNAPSFCPLVVLPSL
TEKVSLDSWQSLALSSVVVDPSIRHFDVAHVSTAATSNFSAVRDLCLSECSQHEACLITTLQTQPGAVRCMFYADTQSCTHSLQGQNCRL
LLREEATHIYRKPGISLLSYEASVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASC
WQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNW
GLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPM
SSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTS
SKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLEL
LADVQFALGLPFYPAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKAD
CSFWSKYISSLKTSADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>2828_2828_5_AGAP3-TG_AGAP3_chr7_150784159_ENST00000473312_TG_chr8_133961021_ENST00000377869_length(transcript)=3510nt_BP=331nt
ATGAACTTCCAGGCGGGCGGGGGGCAGAGCCCGCAGCAGCAGCAGAGCCTGGCGGCTCCGGGGGGCGGCGGCGCTGCCGCGCAGCAGCTC
GTCTGCGGCGGGCAGTTCGGCGGCGCGGGGCCCGGGGCCGGGGGCGGCGGCGGCCCCTCGCAGCAGCTGGCCGGCGGGCCCCCCCAGCAG
TTCGCGCTCTCCAACTCCGCGGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCCGTGCATCCCAATATCTACGCCATCTACGACCTGATC
GAGCGCATCGAGGATTTGGCGCTGCAGAACCAGATCCGGGAGCACGTCATCTCCATCGAGGGTGCCATCATCTGTGGGTTGCTGAGCTCA
CCCAGTGTCCTGCTTTGTAATGTCAAAGACTGGATGGATCCCTCTGAAGCCTGGGCTAATGCTACATGTCCTGGTGTGACATATGACCAG
GAGAGCCACCAGGTGATATTGCGTCTTGGAGACCAGGAGTTCATCAAGAGTCTGACACCCTTAGAAGGAACTCAAGACACCTTTACCAAT
TTTCAGCAGGTTTATCTCTGGAAAGATTCTGACATGGGGTCTCGGCCTGAGTCTATGGGATGTAGAAAAGACACAGTGCCAAGGCCAGCA
TCTCCAACAGAAGCAGGTTTGACAACAGAACTTTTCTCCCCTGTGGACCTCAACCAGGTCATTGTCAATGGAAATCAATCACTATCCAGC
CAGAAGCACTGGCTTTTCAAGCACCTGTTTTCAGCCCAGCAGGCAAACCTATGGTGCCTTTCTCGTTGTGTGCAGGAGCACTCTTTCTGT
CAGCTCGCAGAGATAACAGAGAGTGCATCCTTGTACTTCACCTGCACCCTCTACCCAGAGGCACAGGTGTGTGATGACATCATGGAGTCC
AATGCCCAGGGCTGCAGACTGATCCTGCCTCAGATGCCAAAGGCCCTGTTCCGGAAGAAAGTTATACTGGAAGATAAAGTGAAGAACTTT
TACACTCGCCTGCCGTTCCAAAAACTGATGGGGATATCCATTAGAAATAAAGTGCCCATGTCTGAAAAATCTATTTCTAATGGGTTCTTT
GAATGTGAACGACGGTGCGATGCGGACCCATGCTGCACTGGCTTTGGATTTCTAAATGTTTCCCAGTTAAAAGGAGGAGAGGTGACATGT
CTCACTCTGAACAGCTTGGGAATTCAGATGTGCAGTGAGGAGAATGGAGGAGCCTGGCGCATTTTGGACTGTGGCTCTCCTGACATTGAA
GTCCACACCTATCCCTTCGGATGGTACCAGAAGCCCATTGCTCAAAATAATGCTCCCAGTTTTTGCCCTTTGGTTGTTCTGCCTTCCCTC
ACAGAGAAAGTGTCTCTGGACTCGTGGCAGTCCCTGGCCCTCTCTTCAGTGGTTGTTGATCCATCCATTAGGCACTTTGATGTTGCCCAT
GTCAGCACTGCTGCCACCAGCAATTTCTCTGCTGTCCGAGACCTCTGTTTGTCGGAATGTTCCCAACATGAGGCCTGTCTCATCACCACT
CTGCAAACCCAACCTGGGGCTGTGAGATGTATGTTCTATGCTGATACTCAAAGCTGCACACATAGTCTGCAGGGTCAGAACTGCCGACTT
CTGCTTCGTGAAGAGGCCACCCACATCTACCGGAAGCCAGGAATCTCTCTGCTCAGCTATGAGGCATCTGTACCTTCTGTGCCCATTTCC
ACCCATGGCCGGCTGCTGGGCAGGTCCCAGGCCATCCAGGTGGGTACCTCATGGAAGCAAGTGGACCAGTTCCTTGGAGTTCCATATGCT
GCCCCGCCCCTGGCAGAGAGGCGCTTCCAGGCACCAGAGCCCTTGAACTGGACAGGCTCCTGGGATGCCAGCAAGCCAAGGGCCAGCTGC
TGGCAGCCAGGCACCAGAACATCCACGTCTCCTGGAGTCAGTGAAGATTGTTTGTATCTCAATGTGTTCATCCCTCAGAATGTGGCCCCT
AACGCGTCTGTGCTGGTGTTCTTCCACAACACCATGGACAGGGAGGAGAGTGAAGGATGGCCGGCTATCGACGGCTCCTTCTTGGCTGCT
GTTGGCAACCTCATCGTGGTCACTGCCAGCTACCGAGTGGGTGTCTTCGGCTTCCTGAGTTCTGGGTCCGGAGAGGTGAGTGGCAACTGG
GGGCTGCTGGACCAGGTGGCGGCTCTGACCTGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGGCAGCA
GACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGATGGGA
GGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATG
TCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTGGC
CCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAGAGGTC
GATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGT
AGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTAC
TCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTATAATC
GACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGGAGCTG
CTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAA
ATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCCCC
TGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAGCCGAC
TGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAG
TTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTGAGCTC
CCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATGCGGTGAA


>2828_2828_5_AGAP3-TG_AGAP3_chr7_150784159_ENST00000473312_TG_chr8_133961021_ENST00000377869_length(amino acids)=1134AA_BP=105
MNFQAGGGQSPQQQQSLAAPGGGGAAAQQLVCGGQFGGAGPGAGGGGGPSQQLAGGPPQQFALSNSAAIRAEIQRFESVHPNIYAIYDLI
ERIEDLALQNQIREHVISIEGAIICGLLSSPSVLLCNVKDWMDPSEAWANATCPGVTYDQESHQVILRLGDQEFIKSLTPLEGTQDTFTN
FQQVYLWKDSDMGSRPESMGCRKDTVPRPASPTEAGLTTELFSPVDLNQVIVNGNQSLSSQKHWLFKHLFSAQQANLWCLSRCVQEHSFC
QLAEITESASLYFTCTLYPEAQVCDDIMESNAQGCRLILPQMPKALFRKKVILEDKVKNFYTRLPFQKLMGISIRNKVPMSEKSISNGFF
ECERRCDADPCCTGFGFLNVSQLKGGEVTCLTLNSLGIQMCSEENGGAWRILDCGSPDIEVHTYPFGWYQKPIAQNNAPSFCPLVVLPSL
TEKVSLDSWQSLALSSVVVDPSIRHFDVAHVSTAATSNFSAVRDLCLSECSQHEACLITTLQTQPGAVRCMFYADTQSCTHSLQGQNCRL
LLREEATHIYRKPGISLLSYEASVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASC
WQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNW
GLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPM
SSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTS
SKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLEL
LADVQFALGLPFYPAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKAD
CSFWSKYISSLKTSADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>2828_2828_6_AGAP3-TG_AGAP3_chr7_150784159_ENST00000473312_TG_chr8_133961021_ENST00000542445_length(transcript)=3438nt_BP=331nt
ATGAACTTCCAGGCGGGCGGGGGGCAGAGCCCGCAGCAGCAGCAGAGCCTGGCGGCTCCGGGGGGCGGCGGCGCTGCCGCGCAGCAGCTC
GTCTGCGGCGGGCAGTTCGGCGGCGCGGGGCCCGGGGCCGGGGGCGGCGGCGGCCCCTCGCAGCAGCTGGCCGGCGGGCCCCCCCAGCAG
TTCGCGCTCTCCAACTCCGCGGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCCGTGCATCCCAATATCTACGCCATCTACGACCTGATC
GAGCGCATCGAGGATTTGGCGCTGCAGAACCAGATCCGGGAGCACGTCATCTCCATCGAGGGTGCCATCATCTGTGGGTTGCTGAGCTCA
CCCAGTGTCCTGCTTTGTAATGTCAAAGACTGGATGGATCCCTCTGAAGCCTGGGCTAATGCTACATGTCCTGGTGTGACATATGACCAG
GAGAGCCACCAGGTGATATTGCGTCTTGGAGACCAGGAGTTCATCAAGAGTCTGACACCCTTAGAAGGAACTCAAGACACCTTTACCAAT
TTTCAGCAGGTTTATCTCTGGAAAGATTCTGACATGGGGTCTCGGCCTGAGTCTATGGGATGTAGAAAAGACACAGTGCCAAGGCCAGCA
TCTCCAACAGAAGCAGGTTTGACAACAGAACTTTTCTCCCCTGTGGACCTCAACCAGGTCATTGTCAATGGAAATCAATCACTATCCAGC
CAGAAGCACTGGCTTTTCAAGCACCTGTTTTCAGCCCAGCAGGCAAACCTATGGTGCCTTTCTCGTTGTGTGCAGGAGCACTCTTTCTGT
CAGCTCGCAGAGATAACAGAGAGTGCATCCTTGTACTTCACCTGCACCCTCTACCCAGAGGCACAGGTGTGTGATGACATCATGGAGTCC
AATGCCCAGGGCTGCAGACTGATCCTGCCTCAGATGCCAAAGGCCCTGTTCCGGAAGAAAGTTATACTGGAAGATAAAGTGAAGAACTTT
TACACTCGCCTGCCGTTCCAAAAACTGATGGGGATATCCATTAGAAATAAAGTGCCCATGTCTGAAAAATCTATTTCTAATGGGTTCTTT
GAATGTGAACGACGGTGCGATGCGGACCCATGCTGCACTGGCTTTGGATTTCTAAATGTTTCCCAGTTAAAAGGAGGAGAGGTGACATGT
CTCACTCTGAACAGCTTGGGAATTCAGATGTGCAGTGAGGAGAATGGAGGAGCCTGGCGCATTTTGGACTGTGGCTCTCCTGACATTGAA
GTCCACACCTATCCCTTCGGATGGTACCAGAAGCCCATTGCTCAAAATAATGCTCCCAGTTTTTGCCCTTTGGTTGTTCTGCCTTCCCTC
ACAGAGAAAGTGTCTCTGGACTCGTGGCAGTCCCTGGCCCTCTCTTCAGTGGTTGTTGATCCATCCATTAGGCACTTTGATGTTGCCCAT
GTCAGCACTGCTGCCACCAGCAATTTCTCTGCTGTCCGAGACCTCTGTTTGTCGGAATGTTCCCAACATGAGGCCTGTCTCATCACCACT
CTGCAAACCCAACCTGGGGCTGTGAGATGTATGTTCTATGCTGATACTCAAAGCTGCACACATAGTCTGCAGGGTCAGAACTGCCGACTT
CTGCTTCGTGAAGAGGCCACCCACATCTACCGGAAGCCAGGAATCTCTCTGCTCAGCTATGAGGCATCTGTACCTTCTGTGCCCATTTCC
ACCCATGGCCGGCTGCTGGGCAGGTCCCAGGCCATCCAGGTGGGTACCTCATGGAAGCAAGTGGACCAGTTCCTTGGAGTTCCATATGCT
GCCCCGCCCCTGGCAGAGAGGCGCTTCCAGGCACCAGAGCCCTTGAACTGGACAGGCTCCTGGGATGCCAGCAAGCCAAGGGCCAGCTGC
TGGCAGCCAGGCACCAGAACATCCACGTCTCCTGGAGTCAGTGAAGATTGTTTGTATCTCAATGTGTTCATCCCTCAGAATGTGGCCCCT
AACGCGTCTGTGCTGGTGTTCTTCCACAACACCATGGACAGGGAGGAGAGTGAAGGATGGCCGGCTATCGACGGCTCCTTCTTGGCTGCT
GTTGGCAACCTCATCGTGGTCACTGCCAGCTACCGAGTGGGTGTCTTCGGCTTCCTGAGTTCTGGGTCCGGAGAGGTGAGTGGCAACTGG
GGGCTGCTGGACCAGGTGGCGGCTCTGACCTGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGGCAGCA
GACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGATGGGA
GGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATG
TCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTGGC
CCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAGAGGTC
GATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGT
AGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTAC
TCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTATAATC
GACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGGAGCTG
CTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAA
ATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCCCC
TGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAGCCGAC
TGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAG
TTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTGAGCTC
CCCAAAAACCTCACCCGA

>2828_2828_6_AGAP3-TG_AGAP3_chr7_150784159_ENST00000473312_TG_chr8_133961021_ENST00000542445_length(amino acids)=1134AA_BP=105
MNFQAGGGQSPQQQQSLAAPGGGGAAAQQLVCGGQFGGAGPGAGGGGGPSQQLAGGPPQQFALSNSAAIRAEIQRFESVHPNIYAIYDLI
ERIEDLALQNQIREHVISIEGAIICGLLSSPSVLLCNVKDWMDPSEAWANATCPGVTYDQESHQVILRLGDQEFIKSLTPLEGTQDTFTN
FQQVYLWKDSDMGSRPESMGCRKDTVPRPASPTEAGLTTELFSPVDLNQVIVNGNQSLSSQKHWLFKHLFSAQQANLWCLSRCVQEHSFC
QLAEITESASLYFTCTLYPEAQVCDDIMESNAQGCRLILPQMPKALFRKKVILEDKVKNFYTRLPFQKLMGISIRNKVPMSEKSISNGFF
ECERRCDADPCCTGFGFLNVSQLKGGEVTCLTLNSLGIQMCSEENGGAWRILDCGSPDIEVHTYPFGWYQKPIAQNNAPSFCPLVVLPSL
TEKVSLDSWQSLALSSVVVDPSIRHFDVAHVSTAATSNFSAVRDLCLSECSQHEACLITTLQTQPGAVRCMFYADTQSCTHSLQGQNCRL
LLREEATHIYRKPGISLLSYEASVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASC
WQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNW
GLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPM
SSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTS
SKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLEL
LADVQFALGLPFYPAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKAD
CSFWSKYISSLKTSADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>2828_2828_7_AGAP3-TG_AGAP3_chr7_150784159_ENST00000479901_TG_chr8_133961021_ENST00000220616_length(transcript)=3508nt_BP=331nt
ATGAACTTCCAGGCGGGCGGGGGGCAGAGCCCGCAGCAGCAGCAGAGCCTGGCGGCTCCGGGGGGCGGCGGCGCTGCCGCGCAGCAGCTC
GTCTGCGGCGGGCAGTTCGGCGGCGCGGGGCCCGGGGCCGGGGGCGGCGGCGGCCCCTCGCAGCAGCTGGCCGGCGGGCCCCCCCAGCAG
TTCGCGCTCTCCAACTCCGCGGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCCGTGCATCCCAATATCTACGCCATCTACGACCTGATC
GAGCGCATCGAGGATTTGGCGCTGCAGAACCAGATCCGGGAGCACGTCATCTCCATCGAGGGTGCCATCATCTGTGGGTTGCTGAGCTCA
CCCAGTGTCCTGCTTTGTAATGTCAAAGACTGGATGGATCCCTCTGAAGCCTGGGCTAATGCTACATGTCCTGGTGTGACATATGACCAG
GAGAGCCACCAGGTGATATTGCGTCTTGGAGACCAGGAGTTCATCAAGAGTCTGACACCCTTAGAAGGAACTCAAGACACCTTTACCAAT
TTTCAGCAGGTTTATCTCTGGAAAGATTCTGACATGGGGTCTCGGCCTGAGTCTATGGGATGTAGAAAAGACACAGTGCCAAGGCCAGCA
TCTCCAACAGAAGCAGGTTTGACAACAGAACTTTTCTCCCCTGTGGACCTCAACCAGGTCATTGTCAATGGAAATCAATCACTATCCAGC
CAGAAGCACTGGCTTTTCAAGCACCTGTTTTCAGCCCAGCAGGCAAACCTATGGTGCCTTTCTCGTTGTGTGCAGGAGCACTCTTTCTGT
CAGCTCGCAGAGATAACAGAGAGTGCATCCTTGTACTTCACCTGCACCCTCTACCCAGAGGCACAGGTGTGTGATGACATCATGGAGTCC
AATGCCCAGGGCTGCAGACTGATCCTGCCTCAGATGCCAAAGGCCCTGTTCCGGAAGAAAGTTATACTGGAAGATAAAGTGAAGAACTTT
TACACTCGCCTGCCGTTCCAAAAACTGATGGGGATATCCATTAGAAATAAAGTGCCCATGTCTGAAAAATCTATTTCTAATGGGTTCTTT
GAATGTGAACGACGGTGCGATGCGGACCCATGCTGCACTGGCTTTGGATTTCTAAATGTTTCCCAGTTAAAAGGAGGAGAGGTGACATGT
CTCACTCTGAACAGCTTGGGAATTCAGATGTGCAGTGAGGAGAATGGAGGAGCCTGGCGCATTTTGGACTGTGGCTCTCCTGACATTGAA
GTCCACACCTATCCCTTCGGATGGTACCAGAAGCCCATTGCTCAAAATAATGCTCCCAGTTTTTGCCCTTTGGTTGTTCTGCCTTCCCTC
ACAGAGAAAGTGTCTCTGGACTCGTGGCAGTCCCTGGCCCTCTCTTCAGTGGTTGTTGATCCATCCATTAGGCACTTTGATGTTGCCCAT
GTCAGCACTGCTGCCACCAGCAATTTCTCTGCTGTCCGAGACCTCTGTTTGTCGGAATGTTCCCAACATGAGGCCTGTCTCATCACCACT
CTGCAAACCCAACCTGGGGCTGTGAGATGTATGTTCTATGCTGATACTCAAAGCTGCACACATAGTCTGCAGGGTCAGAACTGCCGACTT
CTGCTTCGTGAAGAGGCCACCCACATCTACCGGAAGCCAGGAATCTCTCTGCTCAGCTATGAGGCATCTGTACCTTCTGTGCCCATTTCC
ACCCATGGCCGGCTGCTGGGCAGGTCCCAGGCCATCCAGGTGGGTACCTCATGGAAGCAAGTGGACCAGTTCCTTGGAGTTCCATATGCT
GCCCCGCCCCTGGCAGAGAGGCGCTTCCAGGCACCAGAGCCCTTGAACTGGACAGGCTCCTGGGATGCCAGCAAGCCAAGGGCCAGCTGC
TGGCAGCCAGGCACCAGAACATCCACGTCTCCTGGAGTCAGTGAAGATTGTTTGTATCTCAATGTGTTCATCCCTCAGAATGTGGCCCCT
AACGCGTCTGTGCTGGTGTTCTTCCACAACACCATGGACAGGGAGGAGAGTGAAGGATGGCCGGCTATCGACGGCTCCTTCTTGGCTGCT
GTTGGCAACCTCATCGTGGTCACTGCCAGCTACCGAGTGGGTGTCTTCGGCTTCCTGAGTTCTGGGTCCGGAGAGGTGAGTGGCAACTGG
GGGCTGCTGGACCAGGTGGCGGCTCTGACCTGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGGCAGCA
GACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGATGGGA
GGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATG
TCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTGGC
CCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAGAGGTC
GATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGT
AGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTAC
TCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTATAATC
GACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGGAGCTG
CTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAA
ATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCCCC
TGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAGCCGAC
TGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAG
TTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTGAGCTC
CCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATGCGGTG

>2828_2828_7_AGAP3-TG_AGAP3_chr7_150784159_ENST00000479901_TG_chr8_133961021_ENST00000220616_length(amino acids)=1134AA_BP=105
MNFQAGGGQSPQQQQSLAAPGGGGAAAQQLVCGGQFGGAGPGAGGGGGPSQQLAGGPPQQFALSNSAAIRAEIQRFESVHPNIYAIYDLI
ERIEDLALQNQIREHVISIEGAIICGLLSSPSVLLCNVKDWMDPSEAWANATCPGVTYDQESHQVILRLGDQEFIKSLTPLEGTQDTFTN
FQQVYLWKDSDMGSRPESMGCRKDTVPRPASPTEAGLTTELFSPVDLNQVIVNGNQSLSSQKHWLFKHLFSAQQANLWCLSRCVQEHSFC
QLAEITESASLYFTCTLYPEAQVCDDIMESNAQGCRLILPQMPKALFRKKVILEDKVKNFYTRLPFQKLMGISIRNKVPMSEKSISNGFF
ECERRCDADPCCTGFGFLNVSQLKGGEVTCLTLNSLGIQMCSEENGGAWRILDCGSPDIEVHTYPFGWYQKPIAQNNAPSFCPLVVLPSL
TEKVSLDSWQSLALSSVVVDPSIRHFDVAHVSTAATSNFSAVRDLCLSECSQHEACLITTLQTQPGAVRCMFYADTQSCTHSLQGQNCRL
LLREEATHIYRKPGISLLSYEASVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASC
WQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNW
GLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPM
SSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTS
SKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLEL
LADVQFALGLPFYPAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKAD
CSFWSKYISSLKTSADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>2828_2828_8_AGAP3-TG_AGAP3_chr7_150784159_ENST00000479901_TG_chr8_133961021_ENST00000377869_length(transcript)=3510nt_BP=331nt
ATGAACTTCCAGGCGGGCGGGGGGCAGAGCCCGCAGCAGCAGCAGAGCCTGGCGGCTCCGGGGGGCGGCGGCGCTGCCGCGCAGCAGCTC
GTCTGCGGCGGGCAGTTCGGCGGCGCGGGGCCCGGGGCCGGGGGCGGCGGCGGCCCCTCGCAGCAGCTGGCCGGCGGGCCCCCCCAGCAG
TTCGCGCTCTCCAACTCCGCGGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCCGTGCATCCCAATATCTACGCCATCTACGACCTGATC
GAGCGCATCGAGGATTTGGCGCTGCAGAACCAGATCCGGGAGCACGTCATCTCCATCGAGGGTGCCATCATCTGTGGGTTGCTGAGCTCA
CCCAGTGTCCTGCTTTGTAATGTCAAAGACTGGATGGATCCCTCTGAAGCCTGGGCTAATGCTACATGTCCTGGTGTGACATATGACCAG
GAGAGCCACCAGGTGATATTGCGTCTTGGAGACCAGGAGTTCATCAAGAGTCTGACACCCTTAGAAGGAACTCAAGACACCTTTACCAAT
TTTCAGCAGGTTTATCTCTGGAAAGATTCTGACATGGGGTCTCGGCCTGAGTCTATGGGATGTAGAAAAGACACAGTGCCAAGGCCAGCA
TCTCCAACAGAAGCAGGTTTGACAACAGAACTTTTCTCCCCTGTGGACCTCAACCAGGTCATTGTCAATGGAAATCAATCACTATCCAGC
CAGAAGCACTGGCTTTTCAAGCACCTGTTTTCAGCCCAGCAGGCAAACCTATGGTGCCTTTCTCGTTGTGTGCAGGAGCACTCTTTCTGT
CAGCTCGCAGAGATAACAGAGAGTGCATCCTTGTACTTCACCTGCACCCTCTACCCAGAGGCACAGGTGTGTGATGACATCATGGAGTCC
AATGCCCAGGGCTGCAGACTGATCCTGCCTCAGATGCCAAAGGCCCTGTTCCGGAAGAAAGTTATACTGGAAGATAAAGTGAAGAACTTT
TACACTCGCCTGCCGTTCCAAAAACTGATGGGGATATCCATTAGAAATAAAGTGCCCATGTCTGAAAAATCTATTTCTAATGGGTTCTTT
GAATGTGAACGACGGTGCGATGCGGACCCATGCTGCACTGGCTTTGGATTTCTAAATGTTTCCCAGTTAAAAGGAGGAGAGGTGACATGT
CTCACTCTGAACAGCTTGGGAATTCAGATGTGCAGTGAGGAGAATGGAGGAGCCTGGCGCATTTTGGACTGTGGCTCTCCTGACATTGAA
GTCCACACCTATCCCTTCGGATGGTACCAGAAGCCCATTGCTCAAAATAATGCTCCCAGTTTTTGCCCTTTGGTTGTTCTGCCTTCCCTC
ACAGAGAAAGTGTCTCTGGACTCGTGGCAGTCCCTGGCCCTCTCTTCAGTGGTTGTTGATCCATCCATTAGGCACTTTGATGTTGCCCAT
GTCAGCACTGCTGCCACCAGCAATTTCTCTGCTGTCCGAGACCTCTGTTTGTCGGAATGTTCCCAACATGAGGCCTGTCTCATCACCACT
CTGCAAACCCAACCTGGGGCTGTGAGATGTATGTTCTATGCTGATACTCAAAGCTGCACACATAGTCTGCAGGGTCAGAACTGCCGACTT
CTGCTTCGTGAAGAGGCCACCCACATCTACCGGAAGCCAGGAATCTCTCTGCTCAGCTATGAGGCATCTGTACCTTCTGTGCCCATTTCC
ACCCATGGCCGGCTGCTGGGCAGGTCCCAGGCCATCCAGGTGGGTACCTCATGGAAGCAAGTGGACCAGTTCCTTGGAGTTCCATATGCT
GCCCCGCCCCTGGCAGAGAGGCGCTTCCAGGCACCAGAGCCCTTGAACTGGACAGGCTCCTGGGATGCCAGCAAGCCAAGGGCCAGCTGC
TGGCAGCCAGGCACCAGAACATCCACGTCTCCTGGAGTCAGTGAAGATTGTTTGTATCTCAATGTGTTCATCCCTCAGAATGTGGCCCCT
AACGCGTCTGTGCTGGTGTTCTTCCACAACACCATGGACAGGGAGGAGAGTGAAGGATGGCCGGCTATCGACGGCTCCTTCTTGGCTGCT
GTTGGCAACCTCATCGTGGTCACTGCCAGCTACCGAGTGGGTGTCTTCGGCTTCCTGAGTTCTGGGTCCGGAGAGGTGAGTGGCAACTGG
GGGCTGCTGGACCAGGTGGCGGCTCTGACCTGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGGCAGCA
GACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGATGGGA
GGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATG
TCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTGGC
CCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAGAGGTC
GATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGT
AGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTAC
TCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTATAATC
GACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGGAGCTG
CTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAA
ATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCCCC
TGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAGCCGAC
TGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAG
TTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTGAGCTC
CCCAAAAACCTCACCCGAGGCTGCCCACTATGGTCATCTTTTTCTCTAAAATAGCCACTTACCTTCAATAAAGTATCTACATGCGGTGAA


>2828_2828_8_AGAP3-TG_AGAP3_chr7_150784159_ENST00000479901_TG_chr8_133961021_ENST00000377869_length(amino acids)=1134AA_BP=105
MNFQAGGGQSPQQQQSLAAPGGGGAAAQQLVCGGQFGGAGPGAGGGGGPSQQLAGGPPQQFALSNSAAIRAEIQRFESVHPNIYAIYDLI
ERIEDLALQNQIREHVISIEGAIICGLLSSPSVLLCNVKDWMDPSEAWANATCPGVTYDQESHQVILRLGDQEFIKSLTPLEGTQDTFTN
FQQVYLWKDSDMGSRPESMGCRKDTVPRPASPTEAGLTTELFSPVDLNQVIVNGNQSLSSQKHWLFKHLFSAQQANLWCLSRCVQEHSFC
QLAEITESASLYFTCTLYPEAQVCDDIMESNAQGCRLILPQMPKALFRKKVILEDKVKNFYTRLPFQKLMGISIRNKVPMSEKSISNGFF
ECERRCDADPCCTGFGFLNVSQLKGGEVTCLTLNSLGIQMCSEENGGAWRILDCGSPDIEVHTYPFGWYQKPIAQNNAPSFCPLVVLPSL
TEKVSLDSWQSLALSSVVVDPSIRHFDVAHVSTAATSNFSAVRDLCLSECSQHEACLITTLQTQPGAVRCMFYADTQSCTHSLQGQNCRL
LLREEATHIYRKPGISLLSYEASVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASC
WQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNW
GLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPM
SSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTS
SKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLEL
LADVQFALGLPFYPAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKAD
CSFWSKYISSLKTSADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------
>2828_2828_9_AGAP3-TG_AGAP3_chr7_150784159_ENST00000479901_TG_chr8_133961021_ENST00000542445_length(transcript)=3438nt_BP=331nt
ATGAACTTCCAGGCGGGCGGGGGGCAGAGCCCGCAGCAGCAGCAGAGCCTGGCGGCTCCGGGGGGCGGCGGCGCTGCCGCGCAGCAGCTC
GTCTGCGGCGGGCAGTTCGGCGGCGCGGGGCCCGGGGCCGGGGGCGGCGGCGGCCCCTCGCAGCAGCTGGCCGGCGGGCCCCCCCAGCAG
TTCGCGCTCTCCAACTCCGCGGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCCGTGCATCCCAATATCTACGCCATCTACGACCTGATC
GAGCGCATCGAGGATTTGGCGCTGCAGAACCAGATCCGGGAGCACGTCATCTCCATCGAGGGTGCCATCATCTGTGGGTTGCTGAGCTCA
CCCAGTGTCCTGCTTTGTAATGTCAAAGACTGGATGGATCCCTCTGAAGCCTGGGCTAATGCTACATGTCCTGGTGTGACATATGACCAG
GAGAGCCACCAGGTGATATTGCGTCTTGGAGACCAGGAGTTCATCAAGAGTCTGACACCCTTAGAAGGAACTCAAGACACCTTTACCAAT
TTTCAGCAGGTTTATCTCTGGAAAGATTCTGACATGGGGTCTCGGCCTGAGTCTATGGGATGTAGAAAAGACACAGTGCCAAGGCCAGCA
TCTCCAACAGAAGCAGGTTTGACAACAGAACTTTTCTCCCCTGTGGACCTCAACCAGGTCATTGTCAATGGAAATCAATCACTATCCAGC
CAGAAGCACTGGCTTTTCAAGCACCTGTTTTCAGCCCAGCAGGCAAACCTATGGTGCCTTTCTCGTTGTGTGCAGGAGCACTCTTTCTGT
CAGCTCGCAGAGATAACAGAGAGTGCATCCTTGTACTTCACCTGCACCCTCTACCCAGAGGCACAGGTGTGTGATGACATCATGGAGTCC
AATGCCCAGGGCTGCAGACTGATCCTGCCTCAGATGCCAAAGGCCCTGTTCCGGAAGAAAGTTATACTGGAAGATAAAGTGAAGAACTTT
TACACTCGCCTGCCGTTCCAAAAACTGATGGGGATATCCATTAGAAATAAAGTGCCCATGTCTGAAAAATCTATTTCTAATGGGTTCTTT
GAATGTGAACGACGGTGCGATGCGGACCCATGCTGCACTGGCTTTGGATTTCTAAATGTTTCCCAGTTAAAAGGAGGAGAGGTGACATGT
CTCACTCTGAACAGCTTGGGAATTCAGATGTGCAGTGAGGAGAATGGAGGAGCCTGGCGCATTTTGGACTGTGGCTCTCCTGACATTGAA
GTCCACACCTATCCCTTCGGATGGTACCAGAAGCCCATTGCTCAAAATAATGCTCCCAGTTTTTGCCCTTTGGTTGTTCTGCCTTCCCTC
ACAGAGAAAGTGTCTCTGGACTCGTGGCAGTCCCTGGCCCTCTCTTCAGTGGTTGTTGATCCATCCATTAGGCACTTTGATGTTGCCCAT
GTCAGCACTGCTGCCACCAGCAATTTCTCTGCTGTCCGAGACCTCTGTTTGTCGGAATGTTCCCAACATGAGGCCTGTCTCATCACCACT
CTGCAAACCCAACCTGGGGCTGTGAGATGTATGTTCTATGCTGATACTCAAAGCTGCACACATAGTCTGCAGGGTCAGAACTGCCGACTT
CTGCTTCGTGAAGAGGCCACCCACATCTACCGGAAGCCAGGAATCTCTCTGCTCAGCTATGAGGCATCTGTACCTTCTGTGCCCATTTCC
ACCCATGGCCGGCTGCTGGGCAGGTCCCAGGCCATCCAGGTGGGTACCTCATGGAAGCAAGTGGACCAGTTCCTTGGAGTTCCATATGCT
GCCCCGCCCCTGGCAGAGAGGCGCTTCCAGGCACCAGAGCCCTTGAACTGGACAGGCTCCTGGGATGCCAGCAAGCCAAGGGCCAGCTGC
TGGCAGCCAGGCACCAGAACATCCACGTCTCCTGGAGTCAGTGAAGATTGTTTGTATCTCAATGTGTTCATCCCTCAGAATGTGGCCCCT
AACGCGTCTGTGCTGGTGTTCTTCCACAACACCATGGACAGGGAGGAGAGTGAAGGATGGCCGGCTATCGACGGCTCCTTCTTGGCTGCT
GTTGGCAACCTCATCGTGGTCACTGCCAGCTACCGAGTGGGTGTCTTCGGCTTCCTGAGTTCTGGGTCCGGAGAGGTGAGTGGCAACTGG
GGGCTGCTGGACCAGGTGGCGGCTCTGACCTGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTGTCCCTGGCAGCA
GACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACTCCCAACTTTTCCGGAGAGCTGTGCTGATGGGA
GGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGAGAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATG
TCATCCAGCCAAGAAGTGGTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTGGC
CCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAAGAGGTCTTTATGGGTAGAGGTC
GATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCAAAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGT
AGCAAAACAGCCTTTTACCAGGCACTGCAGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTAC
TCTCTGGAGCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATCTGCCCTATAATC
GACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTCCTGAAAACTACGGCCATGGCAGCCTGGAGCTG
CTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTACCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAA
ATCATGCAGTACTTTTCCCACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCCCC
TGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCGACAGGGCCTGAAGAAAGCCGAC
TGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGATGGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAG
TTGACGGCTGGATCTGGGCTAAGAGAAGATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGACCAGCCCTTGAGCTC
CCCAAAAACCTCACCCGA

>2828_2828_9_AGAP3-TG_AGAP3_chr7_150784159_ENST00000479901_TG_chr8_133961021_ENST00000542445_length(amino acids)=1134AA_BP=105
MNFQAGGGQSPQQQQSLAAPGGGGAAAQQLVCGGQFGGAGPGAGGGGGPSQQLAGGPPQQFALSNSAAIRAEIQRFESVHPNIYAIYDLI
ERIEDLALQNQIREHVISIEGAIICGLLSSPSVLLCNVKDWMDPSEAWANATCPGVTYDQESHQVILRLGDQEFIKSLTPLEGTQDTFTN
FQQVYLWKDSDMGSRPESMGCRKDTVPRPASPTEAGLTTELFSPVDLNQVIVNGNQSLSSQKHWLFKHLFSAQQANLWCLSRCVQEHSFC
QLAEITESASLYFTCTLYPEAQVCDDIMESNAQGCRLILPQMPKALFRKKVILEDKVKNFYTRLPFQKLMGISIRNKVPMSEKSISNGFF
ECERRCDADPCCTGFGFLNVSQLKGGEVTCLTLNSLGIQMCSEENGGAWRILDCGSPDIEVHTYPFGWYQKPIAQNNAPSFCPLVVLPSL
TEKVSLDSWQSLALSSVVVDPSIRHFDVAHVSTAATSNFSAVRDLCLSECSQHEACLITTLQTQPGAVRCMFYADTQSCTHSLQGQNCRL
LLREEATHIYRKPGISLLSYEASVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASC
WQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNW
GLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPM
SSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTS
SKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLEL
LADVQFALGLPFYPAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPNRQGLKKAD
CSFWSKYISSLKTSADGAKGGQSAESEEEELTAGSGLREDLLSLQEPGSKTYSK

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for AGAP3-TG


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AGAP3-TG


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AGAP3-TG


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0342194Thyroid Dyshormonogenesis 38CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneC0018021Goiter2CTD_human
TgeneC1848805Thyroid Dyshormonogenesis 12ORPHANET
TgeneC0003469Anxiety Disorders1CTD_human
TgeneC0004364Autoimmune Diseases1CTD_human
TgeneC0010308Congenital Hypothyroidism1GENOMICS_ENGLAND
TgeneC0011573Endogenous depression1CTD_human
TgeneC0011581Depressive disorder1CTD_human
TgeneC0013336Dwarfism1CTD_human
TgeneC0025193Melancholia1CTD_human
TgeneC0041696Unipolar Depression1CTD_human
TgeneC0086133Depressive Syndrome1CTD_human
TgeneC0282126Depression, Neurotic1CTD_human
TgeneC0376280Anxiety States, Neurotic1CTD_human
TgeneC0677607Hashimoto Disease1CTD_human
TgeneC0920350Autoimmune thyroiditis1CTD_human
TgeneC1279420Anxiety neurosis (finding)1CTD_human