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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Diseases

Fusion gene:AP2M1-AP2M1 (FusionGDB2 ID:HG1173TG1173)

Fusion Gene Summary for AP2M1-AP2M1

check button Fusion gene summary
Fusion gene informationFusion gene name: AP2M1-AP2M1
Fusion gene ID: hg1173tg1173
HgeneTgene
Gene symbol

AP2M1

AP2M1

Gene ID

1173

1173

Gene nameadaptor related protein complex 2 subunit mu 1adaptor related protein complex 2 subunit mu 1
SynonymsAP50|CLAPM1|MRD60|mu2AP50|CLAPM1|MRD60|mu2
Cytomap('AP2M1')('AP2M1')

3q27.1

3q27.1

Type of geneprotein-codingprotein-coding
DescriptionAP-2 complex subunit muAP-2 mu 2 chainHA2 50 kDA subunitadaptin-mu2adaptor protein complex AP-2 subunit muadaptor related protein complex 2 mu 1 subunitadaptor-related protein complex 2 subunit muclathrin adaptor complex AP2, mu subunitclathrin asAP-2 complex subunit muAP-2 mu 2 chainHA2 50 kDA subunitadaptin-mu2adaptor protein complex AP-2 subunit muadaptor related protein complex 2 mu 1 subunitadaptor-related protein complex 2 subunit muclathrin adaptor complex AP2, mu subunitclathrin as
Modification date2020032720200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000292807, ENST00000382456, 
ENST00000439647, ENST00000461733, 
ENST00000411763, 		ENST00000292807, 
ENST00000382456, ENST00000411763, 
ENST00000439647, ENST00000461733, 
Fusion gene scores* DoF score8 X 11 X 6=5289 X 12 X 2=216
# samples 1212
** MAII scorelog2(12/528*10)=-2.13750352374993
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/216*10)=-0.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AP2M1 [Title/Abstract] AND AP2M1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAP2M1(183901458)-AP2M1(183901617), # samples:1
AP2M1(183899716)-AP2M1(183894790), # samples:1
AP2M1(183901820)-AP2M1(183901388), # samples:1
AP2M1(183901391)-AP2M1(183901358), # samples:1
Anticipated loss of major functional domain due to fusion event.AP2M1-AP2M1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
AP2M1-AP2M1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
AP2M1-AP2M1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
AP2M1-AP2M1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneAP2M1

GO:0072583

clathrin-dependent endocytosis

23676497|31104773

TgeneAP2M1

GO:0072583

clathrin-dependent endocytosis

23676497|31104773


check buttonFusion gene breakpoints across AP2M1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across AP2M1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/AAA743965AP2M1chr3

183901458

+AP2M1chr3

183901617

-
ChiTaRS5.0N/AAW996595AP2M1chr3

183899716

+AP2M1chr3

183894790

+
ChiTaRS5.0N/ABM690684AP2M1chr3

183901820

-AP2M1chr3

183901388

+
ChiTaRS5.0N/AT12267AP2M1chr3

183901391

+AP2M1chr3

183901358

-


Top

Fusion Gene ORF analysis for AP2M1-AP2M1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000292807ENST00000292807AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3CDSENST00000292807ENST00000382456AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3CDSENST00000292807ENST00000411763AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3CDSENST00000292807ENST00000439647AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3CDSENST00000382456ENST00000292807AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3CDSENST00000382456ENST00000382456AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3CDSENST00000382456ENST00000411763AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3CDSENST00000382456ENST00000439647AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3CDSENST00000439647ENST00000292807AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3CDSENST00000439647ENST00000382456AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3CDSENST00000439647ENST00000411763AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3CDSENST00000439647ENST00000439647AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3CDSENST00000461733ENST00000292807AP2M1chr3

183899716

+AP2M1chr3

183894790

+
3UTR-3CDSENST00000461733ENST00000292807AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3CDSENST00000461733ENST00000292807AP2M1chr3

183901391

+AP2M1chr3

183901358

-
3UTR-3CDSENST00000461733ENST00000382456AP2M1chr3

183899716

+AP2M1chr3

183894790

+
3UTR-3CDSENST00000461733ENST00000382456AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3CDSENST00000461733ENST00000382456AP2M1chr3

183901391

+AP2M1chr3

183901358

-
3UTR-3CDSENST00000461733ENST00000411763AP2M1chr3

183899716

+AP2M1chr3

183894790

+
3UTR-3CDSENST00000461733ENST00000411763AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3CDSENST00000461733ENST00000411763AP2M1chr3

183901391

+AP2M1chr3

183901358

-
3UTR-3CDSENST00000461733ENST00000439647AP2M1chr3

183899716

+AP2M1chr3

183894790

+
3UTR-3CDSENST00000461733ENST00000439647AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3CDSENST00000461733ENST00000439647AP2M1chr3

183901391

+AP2M1chr3

183901358

-
3UTR-3UTRENST00000292807ENST00000292807AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-3UTRENST00000292807ENST00000382456AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-3UTRENST00000292807ENST00000439647AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-3UTRENST00000292807ENST00000461733AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-3UTRENST00000292807ENST00000461733AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3UTRENST00000382456ENST00000292807AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-3UTRENST00000382456ENST00000382456AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-3UTRENST00000382456ENST00000439647AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-3UTRENST00000382456ENST00000461733AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-3UTRENST00000382456ENST00000461733AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3UTRENST00000439647ENST00000292807AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-3UTRENST00000439647ENST00000382456AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-3UTRENST00000439647ENST00000439647AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-3UTRENST00000439647ENST00000461733AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-3UTRENST00000439647ENST00000461733AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3UTRENST00000461733ENST00000292807AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-3UTRENST00000461733ENST00000382456AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-3UTRENST00000461733ENST00000439647AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-3UTRENST00000461733ENST00000461733AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-3UTRENST00000461733ENST00000461733AP2M1chr3

183901820

-AP2M1chr3

183901388

+
3UTR-3UTRENST00000461733ENST00000461733AP2M1chr3

183901391

+AP2M1chr3

183901358

-
3UTR-intronENST00000292807ENST00000411763AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-intronENST00000382456ENST00000411763AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-intronENST00000439647ENST00000411763AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-intronENST00000461733ENST00000411763AP2M1chr3

183901458

+AP2M1chr3

183901617

-
3UTR-intronENST00000461733ENST00000461733AP2M1chr3

183899716

+AP2M1chr3

183894790

+
5CDS-3UTRENST00000292807ENST00000461733AP2M1chr3

183901391

+AP2M1chr3

183901358

-
5CDS-3UTRENST00000382456ENST00000461733AP2M1chr3

183901391

+AP2M1chr3

183901358

-
5CDS-3UTRENST00000411763ENST00000461733AP2M1chr3

183901391

+AP2M1chr3

183901358

-
5CDS-3UTRENST00000439647ENST00000461733AP2M1chr3

183901391

+AP2M1chr3

183901358

-
5CDS-intronENST00000292807ENST00000461733AP2M1chr3

183899716

+AP2M1chr3

183894790

+
5CDS-intronENST00000382456ENST00000461733AP2M1chr3

183899716

+AP2M1chr3

183894790

+
5CDS-intronENST00000411763ENST00000461733AP2M1chr3

183899716

+AP2M1chr3

183894790

+
5CDS-intronENST00000439647ENST00000461733AP2M1chr3

183899716

+AP2M1chr3

183894790

+
Frame-shiftENST00000292807ENST00000292807AP2M1chr3

183899716

+AP2M1chr3

183894790

+
Frame-shiftENST00000292807ENST00000292807AP2M1chr3

183901391

+AP2M1chr3

183901358

-
Frame-shiftENST00000292807ENST00000382456AP2M1chr3

183899716

+AP2M1chr3

183894790

+
Frame-shiftENST00000292807ENST00000382456AP2M1chr3

183901391

+AP2M1chr3

183901358

-
Frame-shiftENST00000292807ENST00000411763AP2M1chr3

183899716

+AP2M1chr3

183894790

+
Frame-shiftENST00000292807ENST00000411763AP2M1chr3

183901391

+AP2M1chr3

183901358

-
Frame-shiftENST00000292807ENST00000439647AP2M1chr3

183901391

+AP2M1chr3

183901358

-
Frame-shiftENST00000382456ENST00000292807AP2M1chr3

183899716

+AP2M1chr3

183894790

+
Frame-shiftENST00000382456ENST00000292807AP2M1chr3

183901391

+AP2M1chr3

183901358

-
Frame-shiftENST00000382456ENST00000382456AP2M1chr3

183899716

+AP2M1chr3

183894790

+
Frame-shiftENST00000382456ENST00000382456AP2M1chr3

183901391

+AP2M1chr3

183901358

-
Frame-shiftENST00000382456ENST00000411763AP2M1chr3

183899716

+AP2M1chr3

183894790

+
Frame-shiftENST00000382456ENST00000411763AP2M1chr3

183901391

+AP2M1chr3

183901358

-
Frame-shiftENST00000382456ENST00000439647AP2M1chr3

183901391

+AP2M1chr3

183901358

-
Frame-shiftENST00000411763ENST00000292807AP2M1chr3

183899716

+AP2M1chr3

183894790

+
Frame-shiftENST00000411763ENST00000292807AP2M1chr3

183901391

+AP2M1chr3

183901358

-
Frame-shiftENST00000411763ENST00000382456AP2M1chr3

183899716

+AP2M1chr3

183894790

+
Frame-shiftENST00000411763ENST00000382456AP2M1chr3

183901391

+AP2M1chr3

183901358

-
Frame-shiftENST00000411763ENST00000411763AP2M1chr3

183899716

+AP2M1chr3

183894790

+
Frame-shiftENST00000411763ENST00000411763AP2M1chr3

183901391

+AP2M1chr3

183901358

-
Frame-shiftENST00000411763ENST00000439647AP2M1chr3

183901391

+AP2M1chr3

183901358

-
Frame-shiftENST00000439647ENST00000292807AP2M1chr3

183899716

+AP2M1chr3

183894790

+
Frame-shiftENST00000439647ENST00000292807AP2M1chr3

183901391

+AP2M1chr3

183901358

-
Frame-shiftENST00000439647ENST00000382456AP2M1chr3

183899716

+AP2M1chr3

183894790

+
Frame-shiftENST00000439647ENST00000382456AP2M1chr3

183901391

+AP2M1chr3

183901358

-
Frame-shiftENST00000439647ENST00000411763AP2M1chr3

183899716

+AP2M1chr3

183894790

+
Frame-shiftENST00000439647ENST00000411763AP2M1chr3

183901391

+AP2M1chr3

183901358

-
In-frameENST00000292807ENST00000439647AP2M1chr3

183899716

+AP2M1chr3

183894790

+
In-frameENST00000382456ENST00000439647AP2M1chr3

183899716

+AP2M1chr3

183894790

+
In-frameENST00000411763ENST00000439647AP2M1chr3

183899716

+AP2M1chr3

183894790

+
In-frameENST00000439647ENST00000439647AP2M1chr3

183899716

+AP2M1chr3

183894790

+
In-frameENST00000439647ENST00000439647AP2M1chr3

183901391

+AP2M1chr3

183901358

-
intron-3CDSENST00000411763ENST00000292807AP2M1chr3

183901820

-AP2M1chr3

183901388

+
intron-3CDSENST00000411763ENST00000382456AP2M1chr3

183901820

-AP2M1chr3

183901388

+
intron-3CDSENST00000411763ENST00000411763AP2M1chr3

183901820

-AP2M1chr3

183901388

+
intron-3CDSENST00000411763ENST00000439647AP2M1chr3

183901820

-AP2M1chr3

183901388

+
intron-3UTRENST00000411763ENST00000292807AP2M1chr3

183901458

+AP2M1chr3

183901617

-
intron-3UTRENST00000411763ENST00000382456AP2M1chr3

183901458

+AP2M1chr3

183901617

-
intron-3UTRENST00000411763ENST00000439647AP2M1chr3

183901458

+AP2M1chr3

183901617

-
intron-3UTRENST00000411763ENST00000461733AP2M1chr3

183901458

+AP2M1chr3

183901617

-
intron-3UTRENST00000411763ENST00000461733AP2M1chr3

183901820

-AP2M1chr3

183901388

+
intron-intronENST00000411763ENST00000411763AP2M1chr3

183901458

+AP2M1chr3

183901617

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for AP2M1-AP2M1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for AP2M1-AP2M1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:183901458/chr3:183901617)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneAP2M1chr3:183899716chr3:183894790ENST00000292807012170_4340436.0DomainMHD
TgeneAP2M1chr3:183899716chr3:183894790ENST00000382456011170_4340434.0DomainMHD
TgeneAP2M1chr3:183899716chr3:183894790ENST00000439647010170_4340434.0DomainMHD
TgeneAP2M1chr3:183901391chr3:183901358ENST00000292807012170_4340436.0DomainMHD
TgeneAP2M1chr3:183901391chr3:183901358ENST00000382456011170_4340434.0DomainMHD
TgeneAP2M1chr3:183901391chr3:183901358ENST00000439647010170_4340434.0DomainMHD

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAP2M1chr3:183899716chr3:183894790ENST00000292807+112170_4340436.0DomainMHD
HgeneAP2M1chr3:183899716chr3:183894790ENST00000382456+111170_4340434.0DomainMHD
HgeneAP2M1chr3:183899716chr3:183894790ENST00000439647+110170_4340434.0DomainMHD
HgeneAP2M1chr3:183901391chr3:183901358ENST00000292807+112170_4340436.0DomainMHD
HgeneAP2M1chr3:183901391chr3:183901358ENST00000382456+111170_4340434.0DomainMHD
HgeneAP2M1chr3:183901391chr3:183901358ENST00000439647+110170_4340434.0DomainMHD


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Fusion Gene Sequence for AP2M1-AP2M1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for AP2M1-AP2M1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AP2M1-AP2M1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AP2M1-AP2M1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneAP2M1C0004134Ataxia1GENOMICS_ENGLAND
HgeneAP2M1C0036572Seizures1GENOMICS_ENGLAND
HgeneAP2M1C0393702Myoclonic Astatic Epilepsy1ORPHANET
HgeneAP2M1C0557874Global developmental delay1GENOMICS_ENGLAND
HgeneAP2M1C0856975Autistic behavior1GENOMICS_ENGLAND
HgeneAP2M1C1858120Generalized hypotonia1GENOMICS_ENGLAND
HgeneAP2M1C3714756Intellectual Disability1GENOMICS_ENGLAND
TgeneC0004134Ataxia1GENOMICS_ENGLAND
TgeneC0036572Seizures1GENOMICS_ENGLAND
TgeneC0393702Myoclonic Astatic Epilepsy1ORPHANET
TgeneC0557874Global developmental delay1GENOMICS_ENGLAND
TgeneC0856975Autistic behavior1GENOMICS_ENGLAND
TgeneC1858120Generalized hypotonia1GENOMICS_ENGLAND
TgeneC3714756Intellectual Disability1GENOMICS_ENGLAND