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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ADCYAP1R1-GHRHR (FusionGDB2 ID:HG117TG2692)

Fusion Gene Summary for ADCYAP1R1-GHRHR

check button Fusion gene summary
Fusion gene informationFusion gene name: ADCYAP1R1-GHRHR
Fusion gene ID: hg117tg2692
HgeneTgene
Gene symbol

ADCYAP1R1

GHRHR

Gene ID

117

2692

Gene nameADCYAP receptor type Igrowth hormone releasing hormone receptor
SynonymsPAC1|PAC1R|PACAPR|PACAPRIGHRFR|GRFR|IGHD1B|IGHD4
Cytomap('ADCYAP1R1')('GHRHR')

7p14.3

7p14.3

Type of geneprotein-codingprotein-coding
Descriptionpituitary adenylate cyclase-activating polypeptide type I receptorPACAP receptor 1PACAP type I receptorPACAP-R1adenylate cyclase activating polypeptide 1 (pituitary) receptor type Ipituitary adenylate cyclase activating polypeptide 1 receptor type I growth hormone-releasing hormone receptorGHRH receptorGRF receptor
Modification date2020031320200315
UniProtAcc

P41586

.
Ensembl transtripts involved in fusion geneENST00000304166, ENST00000396211, 
ENST00000409363, ENST00000409489, 
Fusion gene scores* DoF score6 X 7 X 3=1262 X 2 X 2=8
# samples 72
** MAII scorelog2(7/126*10)=-0.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: ADCYAP1R1 [Title/Abstract] AND GHRHR [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointADCYAP1R1(31139824)-GHRHR(31014586), # samples:2
Anticipated loss of major functional domain due to fusion event.ADCYAP1R1-GHRHR seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ADCYAP1R1-GHRHR seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ADCYAP1R1-GHRHR seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ADCYAP1R1-GHRHR seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ADCYAP1R1-GHRHR seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
ADCYAP1R1-GHRHR seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneGHRHR

GO:0007189

adenylate cyclase-activating G protein-coupled receptor signaling pathway

1333056|7680413

TgeneGHRHR

GO:0008284

positive regulation of cell proliferation

12867592

TgeneGHRHR

GO:0043627

response to estrogen

9482665

TgeneGHRHR

GO:0051384

response to glucocorticoid

9482665


check buttonFusion gene breakpoints across ADCYAP1R1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across GHRHR (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PCPGTCGA-P8-A5KC-01AADCYAP1R1chr7

31132349

+GHRHRchr7

31014586

+
ChimerDB4PCPGTCGA-P8-A5KC-01AADCYAP1R1chr7

31139824

+GHRHRchr7

31014586

+


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Fusion Gene ORF analysis for ADCYAP1R1-GHRHR

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000304166ENST00000461424ADCYAP1R1chr7

31132349

+GHRHRchr7

31014586

+
5CDS-3UTRENST00000396211ENST00000461424ADCYAP1R1chr7

31132349

+GHRHRchr7

31014586

+
5CDS-3UTRENST00000396211ENST00000461424ADCYAP1R1chr7

31139824

+GHRHRchr7

31014586

+
5CDS-3UTRENST00000409363ENST00000461424ADCYAP1R1chr7

31132349

+GHRHRchr7

31014586

+
5CDS-3UTRENST00000409489ENST00000461424ADCYAP1R1chr7

31132349

+GHRHRchr7

31014586

+
5CDS-3UTRENST00000409489ENST00000461424ADCYAP1R1chr7

31139824

+GHRHRchr7

31014586

+
Frame-shiftENST00000304166ENST00000409316ADCYAP1R1chr7

31132349

+GHRHRchr7

31014586

+
Frame-shiftENST00000396211ENST00000409316ADCYAP1R1chr7

31132349

+GHRHRchr7

31014586

+
Frame-shiftENST00000396211ENST00000409316ADCYAP1R1chr7

31139824

+GHRHRchr7

31014586

+
Frame-shiftENST00000409363ENST00000409316ADCYAP1R1chr7

31132349

+GHRHRchr7

31014586

+
Frame-shiftENST00000409489ENST00000409316ADCYAP1R1chr7

31132349

+GHRHRchr7

31014586

+
Frame-shiftENST00000409489ENST00000409316ADCYAP1R1chr7

31139824

+GHRHRchr7

31014586

+
In-frameENST00000304166ENST00000326139ADCYAP1R1chr7

31132349

+GHRHRchr7

31014586

+
In-frameENST00000304166ENST00000409904ADCYAP1R1chr7

31132349

+GHRHRchr7

31014586

+
In-frameENST00000396211ENST00000326139ADCYAP1R1chr7

31132349

+GHRHRchr7

31014586

+
In-frameENST00000396211ENST00000326139ADCYAP1R1chr7

31139824

+GHRHRchr7

31014586

+
In-frameENST00000396211ENST00000409904ADCYAP1R1chr7

31132349

+GHRHRchr7

31014586

+
In-frameENST00000396211ENST00000409904ADCYAP1R1chr7

31139824

+GHRHRchr7

31014586

+
In-frameENST00000409363ENST00000326139ADCYAP1R1chr7

31132349

+GHRHRchr7

31014586

+
In-frameENST00000409363ENST00000409904ADCYAP1R1chr7

31132349

+GHRHRchr7

31014586

+
In-frameENST00000409489ENST00000326139ADCYAP1R1chr7

31132349

+GHRHRchr7

31014586

+
In-frameENST00000409489ENST00000326139ADCYAP1R1chr7

31139824

+GHRHRchr7

31014586

+
In-frameENST00000409489ENST00000409904ADCYAP1R1chr7

31132349

+GHRHRchr7

31014586

+
In-frameENST00000409489ENST00000409904ADCYAP1R1chr7

31139824

+GHRHRchr7

31014586

+
intron-3CDSENST00000304166ENST00000326139ADCYAP1R1chr7

31139824

+GHRHRchr7

31014586

+
intron-3CDSENST00000304166ENST00000409316ADCYAP1R1chr7

31139824

+GHRHRchr7

31014586

+
intron-3CDSENST00000304166ENST00000409904ADCYAP1R1chr7

31139824

+GHRHRchr7

31014586

+
intron-3CDSENST00000409363ENST00000326139ADCYAP1R1chr7

31139824

+GHRHRchr7

31014586

+
intron-3CDSENST00000409363ENST00000409316ADCYAP1R1chr7

31139824

+GHRHRchr7

31014586

+
intron-3CDSENST00000409363ENST00000409904ADCYAP1R1chr7

31139824

+GHRHRchr7

31014586

+
intron-3UTRENST00000304166ENST00000461424ADCYAP1R1chr7

31139824

+GHRHRchr7

31014586

+
intron-3UTRENST00000409363ENST00000461424ADCYAP1R1chr7

31139824

+GHRHRchr7

31014586

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000396211ADCYAP1R1chr731139824+ENST00000326139GHRHRchr731014586+19451201231660545
ENST00000396211ADCYAP1R1chr731139824+ENST00000409904GHRHRchr731014586+19361201231660545
ENST00000409489ADCYAP1R1chr731139824+ENST00000326139GHRHRchr731014586+19841240261699557
ENST00000409489ADCYAP1R1chr731139824+ENST00000409904GHRHRchr731014586+19751240261699557
ENST00000304166ADCYAP1R1chr731132349+ENST00000326139GHRHRchr731014586+207913352411794517
ENST00000304166ADCYAP1R1chr731132349+ENST00000409904GHRHRchr731014586+207013352411794517
ENST00000409363ADCYAP1R1chr731132349+ENST00000326139GHRHRchr731014586+195012061751665496
ENST00000409363ADCYAP1R1chr731132349+ENST00000409904GHRHRchr731014586+194112061751665496
ENST00000396211ADCYAP1R1chr731132349+ENST00000326139GHRHRchr731014586+18611117231576517
ENST00000396211ADCYAP1R1chr731132349+ENST00000409904GHRHRchr731014586+18521117231576517
ENST00000409489ADCYAP1R1chr731132349+ENST00000326139GHRHRchr731014586+18161072261531501
ENST00000409489ADCYAP1R1chr731132349+ENST00000409904GHRHRchr731014586+18071072261531501

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000396211ENST00000326139ADCYAP1R1chr731139824+GHRHRchr731014586+0.0027581420.99724185
ENST00000396211ENST00000409904ADCYAP1R1chr731139824+GHRHRchr731014586+0.0029177040.9970823
ENST00000409489ENST00000326139ADCYAP1R1chr731139824+GHRHRchr731014586+0.0038271770.99617285
ENST00000409489ENST00000409904ADCYAP1R1chr731139824+GHRHRchr731014586+0.0040482430.9959518
ENST00000304166ENST00000326139ADCYAP1R1chr731132349+GHRHRchr731014586+0.0021074720.99789256
ENST00000304166ENST00000409904ADCYAP1R1chr731132349+GHRHRchr731014586+0.0021893230.99781066
ENST00000409363ENST00000326139ADCYAP1R1chr731132349+GHRHRchr731014586+0.0032764390.9967236
ENST00000409363ENST00000409904ADCYAP1R1chr731132349+GHRHRchr731014586+0.0034623610.9965377
ENST00000396211ENST00000326139ADCYAP1R1chr731132349+GHRHRchr731014586+0.0017775080.99822253
ENST00000396211ENST00000409904ADCYAP1R1chr731132349+GHRHRchr731014586+0.0018762080.9981238
ENST00000409489ENST00000326139ADCYAP1R1chr731132349+GHRHRchr731014586+0.0018802570.9981198
ENST00000409489ENST00000409904ADCYAP1R1chr731132349+GHRHRchr731014586+0.0019860230.998014

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Fusion Genomic Features for ADCYAP1R1-GHRHR


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ADCYAP1R1chr731139824+GHRHRchr731014585+0.0060198830.99398017
ADCYAP1R1chr731132349+GHRHRchr731014585+0.0038357020.9961643
ADCYAP1R1chr731139824+GHRHRchr731014585+0.0060198830.99398017
ADCYAP1R1chr731132349+GHRHRchr731014585+0.0038357020.9961643

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ADCYAP1R1-GHRHR


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:31139824/chr7:31014586)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ADCYAP1R1

P41586

.
FUNCTION: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000304166+1316125_139348469.0RegionNote=Important for ligand binding and specificity
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000396211+1216125_139348497.0RegionNote=Important for ligand binding and specificity
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000409363+1114125_139327448.0RegionNote=Important for ligand binding and specificity
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000396211+1316125_139376497.0RegionNote=Important for ligand binding and specificity
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000304166+1316179_186348469.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000304166+1316206_227348469.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000304166+131621_155348469.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000304166+1316254_268348469.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000304166+1316292_309348469.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000304166+1316333_350348469.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000396211+1216179_186348497.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000396211+1216206_227348497.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000396211+121621_155348497.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000396211+1216254_268348497.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000396211+1216292_309348497.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000396211+1216333_350348497.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000409363+1114179_186327448.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000409363+1114206_227327448.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000409363+111421_155327448.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000409363+1114254_268327448.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000409363+1114292_309327448.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000396211+1316179_186376497.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000396211+1316206_227376497.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000396211+131621_155376497.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000396211+1316254_268376497.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000396211+1316292_309376497.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000396211+1316333_350376497.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000304166+1316156_178348469.0TransmembraneHelical%3B Name%3D1
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000304166+1316187_205348469.0TransmembraneHelical%3B Name%3D2
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000304166+1316228_253348469.0TransmembraneHelical%3B Name%3D3
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000304166+1316269_291348469.0TransmembraneHelical%3B Name%3D4
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000304166+1316310_332348469.0TransmembraneHelical%3B Name%3D5
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000396211+1216156_178348497.0TransmembraneHelical%3B Name%3D1
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000396211+1216187_205348497.0TransmembraneHelical%3B Name%3D2
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000396211+1216228_253348497.0TransmembraneHelical%3B Name%3D3
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000396211+1216269_291348497.0TransmembraneHelical%3B Name%3D4
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000396211+1216310_332348497.0TransmembraneHelical%3B Name%3D5
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000409363+1114156_178327448.0TransmembraneHelical%3B Name%3D1
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000409363+1114187_205327448.0TransmembraneHelical%3B Name%3D2
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000409363+1114228_253327448.0TransmembraneHelical%3B Name%3D3
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000409363+1114269_291327448.0TransmembraneHelical%3B Name%3D4
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000396211+1316156_178376497.0TransmembraneHelical%3B Name%3D1
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000396211+1316187_205376497.0TransmembraneHelical%3B Name%3D2
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000396211+1316228_253376497.0TransmembraneHelical%3B Name%3D3
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000396211+1316269_291376497.0TransmembraneHelical%3B Name%3D4
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000396211+1316310_332376497.0TransmembraneHelical%3B Name%3D5
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000396211+1316351_371376497.0TransmembraneHelical%3B Name%3D6
TgeneGHRHRchr7:31132349chr7:31014586ENST00000326139713305_329270424.0Topological domainCytoplasmic
TgeneGHRHRchr7:31132349chr7:31014586ENST00000326139713349_361270424.0Topological domainExtracellular
TgeneGHRHRchr7:31132349chr7:31014586ENST00000326139713382_423270424.0Topological domainCytoplasmic
TgeneGHRHRchr7:31139824chr7:31014586ENST00000326139713305_329270424.0Topological domainCytoplasmic
TgeneGHRHRchr7:31139824chr7:31014586ENST00000326139713349_361270424.0Topological domainExtracellular
TgeneGHRHRchr7:31139824chr7:31014586ENST00000326139713382_423270424.0Topological domainCytoplasmic
TgeneGHRHRchr7:31132349chr7:31014586ENST00000326139713281_304270424.0TransmembraneHelical%3B Name%3D5
TgeneGHRHRchr7:31132349chr7:31014586ENST00000326139713330_348270424.0TransmembraneHelical%3B Name%3D6
TgeneGHRHRchr7:31132349chr7:31014586ENST00000326139713362_381270424.0TransmembraneHelical%3B Name%3D7
TgeneGHRHRchr7:31139824chr7:31014586ENST00000326139713281_304270424.0TransmembraneHelical%3B Name%3D5
TgeneGHRHRchr7:31139824chr7:31014586ENST00000326139713330_348270424.0TransmembraneHelical%3B Name%3D6
TgeneGHRHRchr7:31139824chr7:31014586ENST00000326139713362_381270424.0TransmembraneHelical%3B Name%3D7

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000304166+116125_1390469.0RegionNote=Important for ligand binding and specificity
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000409363+114125_1390448.0RegionNote=Important for ligand binding and specificity
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000304166+1316372_385348469.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000304166+1316406_468348469.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000396211+1216372_385348497.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000396211+1216406_468348497.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000409363+1114333_350327448.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000409363+1114372_385327448.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000409363+1114406_468327448.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000304166+116179_1860469.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000304166+116206_2270469.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000304166+11621_1550469.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000304166+116254_2680469.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000304166+116292_3090469.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000304166+116333_3500469.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000304166+116372_3850469.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000304166+116406_4680469.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000396211+1316372_385376497.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000396211+1316406_468376497.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000409363+114179_1860448.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000409363+114206_2270448.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000409363+11421_1550448.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000409363+114254_2680448.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000409363+114292_3090448.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000409363+114333_3500448.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000409363+114372_3850448.0Topological domainExtracellular
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000409363+114406_4680448.0Topological domainCytoplasmic
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000304166+1316351_371348469.0TransmembraneHelical%3B Name%3D6
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000304166+1316386_405348469.0TransmembraneHelical%3B Name%3D7
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000396211+1216351_371348497.0TransmembraneHelical%3B Name%3D6
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000396211+1216386_405348497.0TransmembraneHelical%3B Name%3D7
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000409363+1114310_332327448.0TransmembraneHelical%3B Name%3D5
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000409363+1114351_371327448.0TransmembraneHelical%3B Name%3D6
HgeneADCYAP1R1chr7:31132349chr7:31014586ENST00000409363+1114386_405327448.0TransmembraneHelical%3B Name%3D7
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000304166+116156_1780469.0TransmembraneHelical%3B Name%3D1
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000304166+116187_2050469.0TransmembraneHelical%3B Name%3D2
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000304166+116228_2530469.0TransmembraneHelical%3B Name%3D3
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000304166+116269_2910469.0TransmembraneHelical%3B Name%3D4
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000304166+116310_3320469.0TransmembraneHelical%3B Name%3D5
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000304166+116351_3710469.0TransmembraneHelical%3B Name%3D6
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000304166+116386_4050469.0TransmembraneHelical%3B Name%3D7
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000396211+1316386_405376497.0TransmembraneHelical%3B Name%3D7
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000409363+114156_1780448.0TransmembraneHelical%3B Name%3D1
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000409363+114187_2050448.0TransmembraneHelical%3B Name%3D2
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000409363+114228_2530448.0TransmembraneHelical%3B Name%3D3
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000409363+114269_2910448.0TransmembraneHelical%3B Name%3D4
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000409363+114310_3320448.0TransmembraneHelical%3B Name%3D5
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000409363+114351_3710448.0TransmembraneHelical%3B Name%3D6
HgeneADCYAP1R1chr7:31139824chr7:31014586ENST00000409363+114386_4050448.0TransmembraneHelical%3B Name%3D7
TgeneGHRHRchr7:31132349chr7:31014586ENST00000326139713153_162270424.0Topological domainCytoplasmic
TgeneGHRHRchr7:31132349chr7:31014586ENST00000326139713182_204270424.0Topological domainExtracellular
TgeneGHRHRchr7:31132349chr7:31014586ENST00000326139713228_240270424.0Topological domainCytoplasmic
TgeneGHRHRchr7:31132349chr7:31014586ENST0000032613971323_132270424.0Topological domainExtracellular
TgeneGHRHRchr7:31132349chr7:31014586ENST00000326139713263_280270424.0Topological domainExtracellular
TgeneGHRHRchr7:31139824chr7:31014586ENST00000326139713153_162270424.0Topological domainCytoplasmic
TgeneGHRHRchr7:31139824chr7:31014586ENST00000326139713182_204270424.0Topological domainExtracellular
TgeneGHRHRchr7:31139824chr7:31014586ENST00000326139713228_240270424.0Topological domainCytoplasmic
TgeneGHRHRchr7:31139824chr7:31014586ENST0000032613971323_132270424.0Topological domainExtracellular
TgeneGHRHRchr7:31139824chr7:31014586ENST00000326139713263_280270424.0Topological domainExtracellular
TgeneGHRHRchr7:31132349chr7:31014586ENST00000326139713133_152270424.0TransmembraneHelical%3B Name%3D1
TgeneGHRHRchr7:31132349chr7:31014586ENST00000326139713163_181270424.0TransmembraneHelical%3B Name%3D2
TgeneGHRHRchr7:31132349chr7:31014586ENST00000326139713205_227270424.0TransmembraneHelical%3B Name%3D3
TgeneGHRHRchr7:31132349chr7:31014586ENST00000326139713241_262270424.0TransmembraneHelical%3B Name%3D4
TgeneGHRHRchr7:31139824chr7:31014586ENST00000326139713133_152270424.0TransmembraneHelical%3B Name%3D1
TgeneGHRHRchr7:31139824chr7:31014586ENST00000326139713163_181270424.0TransmembraneHelical%3B Name%3D2
TgeneGHRHRchr7:31139824chr7:31014586ENST00000326139713205_227270424.0TransmembraneHelical%3B Name%3D3
TgeneGHRHRchr7:31139824chr7:31014586ENST00000326139713241_262270424.0TransmembraneHelical%3B Name%3D4


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Fusion Gene Sequence for ADCYAP1R1-GHRHR


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>2281_2281_1_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31132349_ENST00000304166_GHRHR_chr7_31014586_ENST00000326139_length(transcript)=2079nt_BP=1335nt
GCGAGCGTGGTCCCCGCGTGCGCACACGCACACGCCGCCGCGCAGGGACACACGGACCCCGGCCGCCAGCCGGCCACACAGGCGCGGAGA
CCCGGCTCGGCGCGCGCTCCTCGGCGCACACGCTCCCCATCCCCGCGCCGCGCGGGCCGCGGACTTGCAGGCTGCGCGTCCTTTGCGGAG
TCTGCCCCGGCCCCACGGACAGGCCCCGCAGTGAGCAGCCCAGAGACACATTGGGGCTGACCTGCCGCTGCTGTCAGTGGGAGGCCAGTG
GTGCTGGCCAAGAAGTGTCATGGCTGGTGTCGTGCACGTTTCCCTGGCTGCTCTCCTCCTGCTGCCTATGGCCCCTGCCATGCATTCTGA
CTGCATCTTCAAGAAGGAGCAAGCCATGTGCCTGGAGAAGATCCAGAGGGCCAATGAGCTGATGGGCTTCAATGATTCCTCTCCAGGCTG
TCCTGGGATGTGGGACAACATCACGTGTTGGAAGCCCGCCCATGTGGGTGAGATGGTCCTGGTCAGCTGCCCTGAGCTCTTCCGAATCTT
CAACCCAGACCAAGTCTGGGAGACCGAAACCATTGGAGAGTCTGATTTTGGTGACAGTAACTCCTTAGATCTCTCAGACATGGGAGTGGT
GAGCCGGAACTGCACGGAGGATGGCTGGTCGGAACCCTTCCCTCATTACTTTGATGCCTGTGGGTTTGATGAATATGAATCTGAGACTGG
GGACCAGGATTATTACTACCTGTCAGTGAAGGCCCTCTACACGGTTGGCTACAGCACATCCCTCGTCACCCTCACCACTGCCATGGTCAT
CCTTTGTCGCTTCCGGAAGCTGCACTGCACACGCAACTTCATCCACATGAACCTGTTTGTGTCGTTCATGCTGAGGGCGATCTCCGTCTT
CATCAAAGACTGGATTCTGTATGCGGAGCAGGACAGCAACCACTGCTTCATCTCCACTGTGGAATGTAAGGCCGTCATGGTTTTCTTCCA
CTACTGTGTTGTGTCCAACTACTTCTGGCTGTTCATCGAGGGCCTGTACCTCTTCACTCTGCTGGTGGAGACCTTCTTCCCTGAAAGGAG
ATACTTCTACTGGTACACCATCATTGGCTGGGGGACCCCAACTGTGTGTGTGACAGTGTGGGCTACGCTGAGACTCTACTTTGATGACAC
AGGCTGCTGGGATATGAATGACAGCACAGCTCTGTGGTGGGTGATCAAAGGCCCTGTGGTTGGCTCTATCATGGTTAACTTTGTGCTTTT
TATTGGCATTATCGTCATCCTTGTGCAGAAACTTCAGTCTCCAGACATGGGAGGCAATGAGTCCAGCATCTACTTGTGCTGGGACCTGGA
CGACACCTCCCCCTACTGGTGGATCATCAAAGGGCCCATTGTCCTCTCGGTCGGGGTGAACTTTGGGCTTTTTCTCAATATTATCCGCAT
CCTGGTGAGGAAACTGGAGCCAGCTCAGGGCAGCCTCCATACCCAGTCTCAGTATTGGCGTCTCTCCAAGTCGACACTTTTCCTGATCCC
ACTCTTTGGAATTCACTACATCATCTTCAACTTCCTGCCAGACAATGCTGGCCTGGGCATCCGCCTCCCCCTGGAGCTGGGACTGGGTTC
CTTCCAGGGCTTCATTGTTGCCATCCTCTACTGCTTCCTCAACCAAGAGGTGAGGACTGAGATCTCACGGAAGTGGCATGGCCATGACCC
TGAGCTTCTGCCAGCCTGGAGGACCCGTGCTAAGTGGACCACGCCTTCCCGCTCGGCGGCAAAGGTGCTGACATCTATGTGCTAGGCTGC
CTCATCACGCCACTGGAGTCCACACTTGAATTTGGGCAGCTACCACGGGTCTGCCATGCTCTGGAGGAGCAAGGGGGCCACATCCCCACC
CCAGCTGTTACCCAGCCCGGGGCAGGTGCAGCCCTTCCTCCCTGTCTCTGCATCTGACTCTCTTTTGAGGTCCCTGTATGTCTACCTCTG
ACTTCTGTGGTCCCTCTGTGTCTGCTCTCATCCATTCCTCTTACTGGGGCCTGGGGCTCTAGCCCAAGGCTCAGAGGAGCCAATAAACCT
GTAAATGAA

>2281_2281_1_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31132349_ENST00000304166_GHRHR_chr7_31014586_ENST00000326139_length(amino acids)=517AA_BP=127
MPLLSVGGQWCWPRSVMAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVL
VSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTS
LVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTL
LVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNE
SSIYLCWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGI
RLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKVLTSMC

--------------------------------------------------------------
>2281_2281_2_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31132349_ENST00000304166_GHRHR_chr7_31014586_ENST00000409904_length(transcript)=2070nt_BP=1335nt
GCGAGCGTGGTCCCCGCGTGCGCACACGCACACGCCGCCGCGCAGGGACACACGGACCCCGGCCGCCAGCCGGCCACACAGGCGCGGAGA
CCCGGCTCGGCGCGCGCTCCTCGGCGCACACGCTCCCCATCCCCGCGCCGCGCGGGCCGCGGACTTGCAGGCTGCGCGTCCTTTGCGGAG
TCTGCCCCGGCCCCACGGACAGGCCCCGCAGTGAGCAGCCCAGAGACACATTGGGGCTGACCTGCCGCTGCTGTCAGTGGGAGGCCAGTG
GTGCTGGCCAAGAAGTGTCATGGCTGGTGTCGTGCACGTTTCCCTGGCTGCTCTCCTCCTGCTGCCTATGGCCCCTGCCATGCATTCTGA
CTGCATCTTCAAGAAGGAGCAAGCCATGTGCCTGGAGAAGATCCAGAGGGCCAATGAGCTGATGGGCTTCAATGATTCCTCTCCAGGCTG
TCCTGGGATGTGGGACAACATCACGTGTTGGAAGCCCGCCCATGTGGGTGAGATGGTCCTGGTCAGCTGCCCTGAGCTCTTCCGAATCTT
CAACCCAGACCAAGTCTGGGAGACCGAAACCATTGGAGAGTCTGATTTTGGTGACAGTAACTCCTTAGATCTCTCAGACATGGGAGTGGT
GAGCCGGAACTGCACGGAGGATGGCTGGTCGGAACCCTTCCCTCATTACTTTGATGCCTGTGGGTTTGATGAATATGAATCTGAGACTGG
GGACCAGGATTATTACTACCTGTCAGTGAAGGCCCTCTACACGGTTGGCTACAGCACATCCCTCGTCACCCTCACCACTGCCATGGTCAT
CCTTTGTCGCTTCCGGAAGCTGCACTGCACACGCAACTTCATCCACATGAACCTGTTTGTGTCGTTCATGCTGAGGGCGATCTCCGTCTT
CATCAAAGACTGGATTCTGTATGCGGAGCAGGACAGCAACCACTGCTTCATCTCCACTGTGGAATGTAAGGCCGTCATGGTTTTCTTCCA
CTACTGTGTTGTGTCCAACTACTTCTGGCTGTTCATCGAGGGCCTGTACCTCTTCACTCTGCTGGTGGAGACCTTCTTCCCTGAAAGGAG
ATACTTCTACTGGTACACCATCATTGGCTGGGGGACCCCAACTGTGTGTGTGACAGTGTGGGCTACGCTGAGACTCTACTTTGATGACAC
AGGCTGCTGGGATATGAATGACAGCACAGCTCTGTGGTGGGTGATCAAAGGCCCTGTGGTTGGCTCTATCATGGTTAACTTTGTGCTTTT
TATTGGCATTATCGTCATCCTTGTGCAGAAACTTCAGTCTCCAGACATGGGAGGCAATGAGTCCAGCATCTACTTGTGCTGGGACCTGGA
CGACACCTCCCCCTACTGGTGGATCATCAAAGGGCCCATTGTCCTCTCGGTCGGGGTGAACTTTGGGCTTTTTCTCAATATTATCCGCAT
CCTGGTGAGGAAACTGGAGCCAGCTCAGGGCAGCCTCCATACCCAGTCTCAGTATTGGCGTCTCTCCAAGTCGACACTTTTCCTGATCCC
ACTCTTTGGAATTCACTACATCATCTTCAACTTCCTGCCAGACAATGCTGGCCTGGGCATCCGCCTCCCCCTGGAGCTGGGACTGGGTTC
CTTCCAGGGCTTCATTGTTGCCATCCTCTACTGCTTCCTCAACCAAGAGGTGAGGACTGAGATCTCACGGAAGTGGCATGGCCATGACCC
TGAGCTTCTGCCAGCCTGGAGGACCCGTGCTAAGTGGACCACGCCTTCCCGCTCGGCGGCAAAGGTGCTGACATCTATGTGCTAGGCTGC
CTCATCACGCCACTGGAGTCCACACTTGAATTTGGGCAGCTACCACGGGTCTGCCATGCTCTGGAGGAGCAAGGGGGCCACATCCCCACC
CCAGCTGTTACCCAGCCCGGGGCAGGTGCAGCCCTTCCTCCCTGTCTCTGCATCTGACTCTCTTTTGAGGTCCCTGTATGTCTACCTCTG
ACTTCTGTGGTCCCTCTGTGTCTGCTCTCATCCATTCCTCTTACTGGGGCCTGGGGCTCTAGCCCAAGGCTCAGAGGAGCCAATAAACCT


>2281_2281_2_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31132349_ENST00000304166_GHRHR_chr7_31014586_ENST00000409904_length(amino acids)=517AA_BP=127
MPLLSVGGQWCWPRSVMAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVL
VSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTS
LVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTL
LVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNE
SSIYLCWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGI
RLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKVLTSMC

--------------------------------------------------------------
>2281_2281_3_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31132349_ENST00000396211_GHRHR_chr7_31014586_ENST00000326139_length(transcript)=1861nt_BP=1117nt
CCCAGAGACACATTGGGGCTGACCTGCCGCTGCTGTCAGTGGGAGGCCAGTGGTGCTGGCCAAGAAGTGTCATGGCTGGTGTCGTGCACG
TTTCCCTGGCTGCTCTCCTCCTGCTGCCTATGGCCCCTGCCATGCATTCTGACTGCATCTTCAAGAAGGAGCAAGCCATGTGCCTGGAGA
AGATCCAGAGGGCCAATGAGCTGATGGGCTTCAATGATTCCTCTCCAGGCTGTCCTGGGATGTGGGACAACATCACGTGTTGGAAGCCCG
CCCATGTGGGTGAGATGGTCCTGGTCAGCTGCCCTGAGCTCTTCCGAATCTTCAACCCAGACCAAGTCTGGGAGACCGAAACCATTGGAG
AGTCTGATTTTGGTGACAGTAACTCCTTAGATCTCTCAGACATGGGAGTGGTGAGCCGGAACTGCACGGAGGATGGCTGGTCGGAACCCT
TCCCTCATTACTTTGATGCCTGTGGGTTTGATGAATATGAATCTGAGACTGGGGACCAGGATTATTACTACCTGTCAGTGAAGGCCCTCT
ACACGGTTGGCTACAGCACATCCCTCGTCACCCTCACCACTGCCATGGTCATCCTTTGTCGCTTCCGGAAGCTGCACTGCACACGCAACT
TCATCCACATGAACCTGTTTGTGTCGTTCATGCTGAGGGCGATCTCCGTCTTCATCAAAGACTGGATTCTGTATGCGGAGCAGGACAGCA
ACCACTGCTTCATCTCCACTGTGGAATGTAAGGCCGTCATGGTTTTCTTCCACTACTGTGTTGTGTCCAACTACTTCTGGCTGTTCATCG
AGGGCCTGTACCTCTTCACTCTGCTGGTGGAGACCTTCTTCCCTGAAAGGAGATACTTCTACTGGTACACCATCATTGGCTGGGGGACCC
CAACTGTGTGTGTGACAGTGTGGGCTACGCTGAGACTCTACTTTGATGACACAGGCTGCTGGGATATGAATGACAGCACAGCTCTGTGGT
GGGTGATCAAAGGCCCTGTGGTTGGCTCTATCATGGTTAACTTTGTGCTTTTTATTGGCATTATCGTCATCCTTGTGCAGAAACTTCAGT
CTCCAGACATGGGAGGCAATGAGTCCAGCATCTACTTGTGCTGGGACCTGGACGACACCTCCCCCTACTGGTGGATCATCAAAGGGCCCA
TTGTCCTCTCGGTCGGGGTGAACTTTGGGCTTTTTCTCAATATTATCCGCATCCTGGTGAGGAAACTGGAGCCAGCTCAGGGCAGCCTCC
ATACCCAGTCTCAGTATTGGCGTCTCTCCAAGTCGACACTTTTCCTGATCCCACTCTTTGGAATTCACTACATCATCTTCAACTTCCTGC
CAGACAATGCTGGCCTGGGCATCCGCCTCCCCCTGGAGCTGGGACTGGGTTCCTTCCAGGGCTTCATTGTTGCCATCCTCTACTGCTTCC
TCAACCAAGAGGTGAGGACTGAGATCTCACGGAAGTGGCATGGCCATGACCCTGAGCTTCTGCCAGCCTGGAGGACCCGTGCTAAGTGGA
CCACGCCTTCCCGCTCGGCGGCAAAGGTGCTGACATCTATGTGCTAGGCTGCCTCATCACGCCACTGGAGTCCACACTTGAATTTGGGCA
GCTACCACGGGTCTGCCATGCTCTGGAGGAGCAAGGGGGCCACATCCCCACCCCAGCTGTTACCCAGCCCGGGGCAGGTGCAGCCCTTCC
TCCCTGTCTCTGCATCTGACTCTCTTTTGAGGTCCCTGTATGTCTACCTCTGACTTCTGTGGTCCCTCTGTGTCTGCTCTCATCCATTCC
TCTTACTGGGGCCTGGGGCTCTAGCCCAAGGCTCAGAGGAGCCAATAAACCTGTAAATGAA

>2281_2281_3_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31132349_ENST00000396211_GHRHR_chr7_31014586_ENST00000326139_length(amino acids)=517AA_BP=127
MPLLSVGGQWCWPRSVMAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVL
VSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTS
LVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTL
LVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNE
SSIYLCWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGI
RLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKVLTSMC

--------------------------------------------------------------
>2281_2281_4_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31132349_ENST00000396211_GHRHR_chr7_31014586_ENST00000409904_length(transcript)=1852nt_BP=1117nt
CCCAGAGACACATTGGGGCTGACCTGCCGCTGCTGTCAGTGGGAGGCCAGTGGTGCTGGCCAAGAAGTGTCATGGCTGGTGTCGTGCACG
TTTCCCTGGCTGCTCTCCTCCTGCTGCCTATGGCCCCTGCCATGCATTCTGACTGCATCTTCAAGAAGGAGCAAGCCATGTGCCTGGAGA
AGATCCAGAGGGCCAATGAGCTGATGGGCTTCAATGATTCCTCTCCAGGCTGTCCTGGGATGTGGGACAACATCACGTGTTGGAAGCCCG
CCCATGTGGGTGAGATGGTCCTGGTCAGCTGCCCTGAGCTCTTCCGAATCTTCAACCCAGACCAAGTCTGGGAGACCGAAACCATTGGAG
AGTCTGATTTTGGTGACAGTAACTCCTTAGATCTCTCAGACATGGGAGTGGTGAGCCGGAACTGCACGGAGGATGGCTGGTCGGAACCCT
TCCCTCATTACTTTGATGCCTGTGGGTTTGATGAATATGAATCTGAGACTGGGGACCAGGATTATTACTACCTGTCAGTGAAGGCCCTCT
ACACGGTTGGCTACAGCACATCCCTCGTCACCCTCACCACTGCCATGGTCATCCTTTGTCGCTTCCGGAAGCTGCACTGCACACGCAACT
TCATCCACATGAACCTGTTTGTGTCGTTCATGCTGAGGGCGATCTCCGTCTTCATCAAAGACTGGATTCTGTATGCGGAGCAGGACAGCA
ACCACTGCTTCATCTCCACTGTGGAATGTAAGGCCGTCATGGTTTTCTTCCACTACTGTGTTGTGTCCAACTACTTCTGGCTGTTCATCG
AGGGCCTGTACCTCTTCACTCTGCTGGTGGAGACCTTCTTCCCTGAAAGGAGATACTTCTACTGGTACACCATCATTGGCTGGGGGACCC
CAACTGTGTGTGTGACAGTGTGGGCTACGCTGAGACTCTACTTTGATGACACAGGCTGCTGGGATATGAATGACAGCACAGCTCTGTGGT
GGGTGATCAAAGGCCCTGTGGTTGGCTCTATCATGGTTAACTTTGTGCTTTTTATTGGCATTATCGTCATCCTTGTGCAGAAACTTCAGT
CTCCAGACATGGGAGGCAATGAGTCCAGCATCTACTTGTGCTGGGACCTGGACGACACCTCCCCCTACTGGTGGATCATCAAAGGGCCCA
TTGTCCTCTCGGTCGGGGTGAACTTTGGGCTTTTTCTCAATATTATCCGCATCCTGGTGAGGAAACTGGAGCCAGCTCAGGGCAGCCTCC
ATACCCAGTCTCAGTATTGGCGTCTCTCCAAGTCGACACTTTTCCTGATCCCACTCTTTGGAATTCACTACATCATCTTCAACTTCCTGC
CAGACAATGCTGGCCTGGGCATCCGCCTCCCCCTGGAGCTGGGACTGGGTTCCTTCCAGGGCTTCATTGTTGCCATCCTCTACTGCTTCC
TCAACCAAGAGGTGAGGACTGAGATCTCACGGAAGTGGCATGGCCATGACCCTGAGCTTCTGCCAGCCTGGAGGACCCGTGCTAAGTGGA
CCACGCCTTCCCGCTCGGCGGCAAAGGTGCTGACATCTATGTGCTAGGCTGCCTCATCACGCCACTGGAGTCCACACTTGAATTTGGGCA
GCTACCACGGGTCTGCCATGCTCTGGAGGAGCAAGGGGGCCACATCCCCACCCCAGCTGTTACCCAGCCCGGGGCAGGTGCAGCCCTTCC
TCCCTGTCTCTGCATCTGACTCTCTTTTGAGGTCCCTGTATGTCTACCTCTGACTTCTGTGGTCCCTCTGTGTCTGCTCTCATCCATTCC
TCTTACTGGGGCCTGGGGCTCTAGCCCAAGGCTCAGAGGAGCCAATAAACCT

>2281_2281_4_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31132349_ENST00000396211_GHRHR_chr7_31014586_ENST00000409904_length(amino acids)=517AA_BP=127
MPLLSVGGQWCWPRSVMAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVL
VSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTS
LVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTL
LVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNE
SSIYLCWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGI
RLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKVLTSMC

--------------------------------------------------------------
>2281_2281_5_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31132349_ENST00000409363_GHRHR_chr7_31014586_ENST00000326139_length(transcript)=1950nt_BP=1206nt
CAGCCGGCCACACAGGCGCGGAGACCCGGCTCGGCGCGCGCTCCTCGGCGCACACGCTCCCCATCCCCGCGCCGCGCGGGCCGCGGACTT
GCAGGCTGCGCGTCCTTTGCGGAGTCTGCCCCGGCCCCACGGACAGGCCCCGCAGTGAGCAGCCCAGAGACACATTGGGGCTGACCTGCC
GCTGCTGTCAGTGGGAGGCCAGTGGTGCTGGCCAAGAAGTGTCATGGCTGGTGTCGTGCACGTTTCCCTGGCTGCTCTCCTCCTGCTGCC
TATGGCCCCTGCCATGCATTCTGACTGCATCTTCAAGAAGGAGCAAGCCATGTGCCTGGAGAAGATCCAGAGGGCCAATGAGCTGATGGG
CTTCAATGATTCCTCTCCAGGCTGTCCTGGGATGTGGGACAACATCACGTGTTGGAAGCCCGCCCATGTGGGTGAGATGGTCCTGGTCAG
CTGCCCTGAGCTCTTCCGAATCTTCAACCCAGACCAAGACATGGGAGTGGTGAGCCGGAACTGCACGGAGGATGGCTGGTCGGAACCCTT
CCCTCATTACTTTGATGCCTGTGGGTTTGATGAATATGAATCTGAGACTGGGGACCAGGATTATTACTACCTGTCAGTGAAGGCCCTCTA
CACGGTTGGCTACAGCACATCCCTCGTCACCCTCACCACTGCCATGGTCATCCTTTGTCGCTTCCGGAAGCTGCACTGCACACGCAACTT
CATCCACATGAACCTGTTTGTGTCGTTCATGCTGAGGGCGATCTCCGTCTTCATCAAAGACTGGATTCTGTATGCGGAGCAGGACAGCAA
CCACTGCTTCATCTCCACTGTGGAATGTAAGGCCGTCATGGTTTTCTTCCACTACTGTGTTGTGTCCAACTACTTCTGGCTGTTCATCGA
GGGCCTGTACCTCTTCACTCTGCTGGTGGAGACCTTCTTCCCTGAAAGGAGATACTTCTACTGGTACACCATCATTGGCTGGGGGACCCC
AACTGTGTGTGTGACAGTGTGGGCTACGCTGAGACTCTACTTTGATGACACAGGCTGCTGGGATATGAATGACAGCACAGCTCTGTGGTG
GGTGATCAAAGGCCCTGTGGTTGGCTCTATCATGGTTAACTTTGTGCTTTTTATTGGCATTATCGTCATCCTTGTGCAGAAACTTCAGTC
TCCAGACATGGGAGGCAATGAGTCCAGCATCTACTTGTGCTGGGACCTGGACGACACCTCCCCCTACTGGTGGATCATCAAAGGGCCCAT
TGTCCTCTCGGTCGGGGTGAACTTTGGGCTTTTTCTCAATATTATCCGCATCCTGGTGAGGAAACTGGAGCCAGCTCAGGGCAGCCTCCA
TACCCAGTCTCAGTATTGGCGTCTCTCCAAGTCGACACTTTTCCTGATCCCACTCTTTGGAATTCACTACATCATCTTCAACTTCCTGCC
AGACAATGCTGGCCTGGGCATCCGCCTCCCCCTGGAGCTGGGACTGGGTTCCTTCCAGGGCTTCATTGTTGCCATCCTCTACTGCTTCCT
CAACCAAGAGGTGAGGACTGAGATCTCACGGAAGTGGCATGGCCATGACCCTGAGCTTCTGCCAGCCTGGAGGACCCGTGCTAAGTGGAC
CACGCCTTCCCGCTCGGCGGCAAAGGTGCTGACATCTATGTGCTAGGCTGCCTCATCACGCCACTGGAGTCCACACTTGAATTTGGGCAG
CTACCACGGGTCTGCCATGCTCTGGAGGAGCAAGGGGGCCACATCCCCACCCCAGCTGTTACCCAGCCCGGGGCAGGTGCAGCCCTTCCT
CCCTGTCTCTGCATCTGACTCTCTTTTGAGGTCCCTGTATGTCTACCTCTGACTTCTGTGGTCCCTCTGTGTCTGCTCTCATCCATTCCT
CTTACTGGGGCCTGGGGCTCTAGCCCAAGGCTCAGAGGAGCCAATAAACCTGTAAATGAA

>2281_2281_5_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31132349_ENST00000409363_GHRHR_chr7_31014586_ENST00000326139_length(amino acids)=496AA_BP=106
MPLLSVGGQWCWPRSVMAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVL
VSCPELFRIFNPDQDMGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTR
NFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWG
TPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLCWDLDDTSPYWWIIKG
PIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGSFQGFIVAILYC
FLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKVLTSMC

--------------------------------------------------------------
>2281_2281_6_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31132349_ENST00000409363_GHRHR_chr7_31014586_ENST00000409904_length(transcript)=1941nt_BP=1206nt
CAGCCGGCCACACAGGCGCGGAGACCCGGCTCGGCGCGCGCTCCTCGGCGCACACGCTCCCCATCCCCGCGCCGCGCGGGCCGCGGACTT
GCAGGCTGCGCGTCCTTTGCGGAGTCTGCCCCGGCCCCACGGACAGGCCCCGCAGTGAGCAGCCCAGAGACACATTGGGGCTGACCTGCC
GCTGCTGTCAGTGGGAGGCCAGTGGTGCTGGCCAAGAAGTGTCATGGCTGGTGTCGTGCACGTTTCCCTGGCTGCTCTCCTCCTGCTGCC
TATGGCCCCTGCCATGCATTCTGACTGCATCTTCAAGAAGGAGCAAGCCATGTGCCTGGAGAAGATCCAGAGGGCCAATGAGCTGATGGG
CTTCAATGATTCCTCTCCAGGCTGTCCTGGGATGTGGGACAACATCACGTGTTGGAAGCCCGCCCATGTGGGTGAGATGGTCCTGGTCAG
CTGCCCTGAGCTCTTCCGAATCTTCAACCCAGACCAAGACATGGGAGTGGTGAGCCGGAACTGCACGGAGGATGGCTGGTCGGAACCCTT
CCCTCATTACTTTGATGCCTGTGGGTTTGATGAATATGAATCTGAGACTGGGGACCAGGATTATTACTACCTGTCAGTGAAGGCCCTCTA
CACGGTTGGCTACAGCACATCCCTCGTCACCCTCACCACTGCCATGGTCATCCTTTGTCGCTTCCGGAAGCTGCACTGCACACGCAACTT
CATCCACATGAACCTGTTTGTGTCGTTCATGCTGAGGGCGATCTCCGTCTTCATCAAAGACTGGATTCTGTATGCGGAGCAGGACAGCAA
CCACTGCTTCATCTCCACTGTGGAATGTAAGGCCGTCATGGTTTTCTTCCACTACTGTGTTGTGTCCAACTACTTCTGGCTGTTCATCGA
GGGCCTGTACCTCTTCACTCTGCTGGTGGAGACCTTCTTCCCTGAAAGGAGATACTTCTACTGGTACACCATCATTGGCTGGGGGACCCC
AACTGTGTGTGTGACAGTGTGGGCTACGCTGAGACTCTACTTTGATGACACAGGCTGCTGGGATATGAATGACAGCACAGCTCTGTGGTG
GGTGATCAAAGGCCCTGTGGTTGGCTCTATCATGGTTAACTTTGTGCTTTTTATTGGCATTATCGTCATCCTTGTGCAGAAACTTCAGTC
TCCAGACATGGGAGGCAATGAGTCCAGCATCTACTTGTGCTGGGACCTGGACGACACCTCCCCCTACTGGTGGATCATCAAAGGGCCCAT
TGTCCTCTCGGTCGGGGTGAACTTTGGGCTTTTTCTCAATATTATCCGCATCCTGGTGAGGAAACTGGAGCCAGCTCAGGGCAGCCTCCA
TACCCAGTCTCAGTATTGGCGTCTCTCCAAGTCGACACTTTTCCTGATCCCACTCTTTGGAATTCACTACATCATCTTCAACTTCCTGCC
AGACAATGCTGGCCTGGGCATCCGCCTCCCCCTGGAGCTGGGACTGGGTTCCTTCCAGGGCTTCATTGTTGCCATCCTCTACTGCTTCCT
CAACCAAGAGGTGAGGACTGAGATCTCACGGAAGTGGCATGGCCATGACCCTGAGCTTCTGCCAGCCTGGAGGACCCGTGCTAAGTGGAC
CACGCCTTCCCGCTCGGCGGCAAAGGTGCTGACATCTATGTGCTAGGCTGCCTCATCACGCCACTGGAGTCCACACTTGAATTTGGGCAG
CTACCACGGGTCTGCCATGCTCTGGAGGAGCAAGGGGGCCACATCCCCACCCCAGCTGTTACCCAGCCCGGGGCAGGTGCAGCCCTTCCT
CCCTGTCTCTGCATCTGACTCTCTTTTGAGGTCCCTGTATGTCTACCTCTGACTTCTGTGGTCCCTCTGTGTCTGCTCTCATCCATTCCT
CTTACTGGGGCCTGGGGCTCTAGCCCAAGGCTCAGAGGAGCCAATAAACCT

>2281_2281_6_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31132349_ENST00000409363_GHRHR_chr7_31014586_ENST00000409904_length(amino acids)=496AA_BP=106
MPLLSVGGQWCWPRSVMAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVL
VSCPELFRIFNPDQDMGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTR
NFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWG
TPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLCWDLDDTSPYWWIIKG
PIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGSFQGFIVAILYC
FLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKVLTSMC

--------------------------------------------------------------
>2281_2281_7_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31132349_ENST00000409489_GHRHR_chr7_31014586_ENST00000326139_length(transcript)=1816nt_BP=1072nt
GCCAGTGGTGCTGGCCAAGAAGTGTCATGGCTGGTGTCGTGCACGTTTCCCTGGCTGCTCTCCTCCTGCTGCCTATGGCCCCTGCCATGC
ATTCTGACTGCATCTTCAAGAAGGAGCAAGCCATGTGCCTGGAGAAGATCCAGAGGGCCAATGAGCTGATGGGCTTCAATGATTCCTCTC
CAGGCTGTCCTGGGATGTGGGACAACATCACGTGTTGGAAGCCCGCCCATGTGGGTGAGATGGTCCTGGTCAGCTGCCCTGAGCTCTTCC
GAATCTTCAACCCAGACCAAGTCTGGGAGACCGAAACCATTGGAGAGTCTGATTTTGGTGACAGTAACTCCTTAGATCTCTCAGACATGG
GAGTGGTGAGCCGGAACTGCACGGAGGATGGCTGGTCGGAACCCTTCCCTCATTACTTTGATGCCTGTGGGTTTGATGAATATGAATCTG
AGACTGGGGACCAGGATTATTACTACCTGTCAGTGAAGGCCCTCTACACGGTTGGCTACAGCACATCCCTCGTCACCCTCACCACTGCCA
TGGTCATCCTTTGTCGCTTCCGGAAGCTGCACTGCACACGCAACTTCATCCACATGAACCTGTTTGTGTCGTTCATGCTGAGGGCGATCT
CCGTCTTCATCAAAGACTGGATTCTGTATGCGGAGCAGGACAGCAACCACTGCTTCATCTCCACTGTGGAATGTAAGGCCGTCATGGTTT
TCTTCCACTACTGTGTTGTGTCCAACTACTTCTGGCTGTTCATCGAGGGCCTGTACCTCTTCACTCTGCTGGTGGAGACCTTCTTCCCTG
AAAGGAGATACTTCTACTGGTACACCATCATTGGCTGGGGGACCCCAACTGTGTGTGTGACAGTGTGGGCTACGCTGAGACTCTACTTTG
ATGACACAGGCTGCTGGGATATGAATGACAGCACAGCTCTGTGGTGGGTGATCAAAGGCCCTGTGGTTGGCTCTATCATGGTTAACTTTG
TGCTTTTTATTGGCATTATCGTCATCCTTGTGCAGAAACTTCAGTCTCCAGACATGGGAGGCAATGAGTCCAGCATCTACTTGTGCTGGG
ACCTGGACGACACCTCCCCCTACTGGTGGATCATCAAAGGGCCCATTGTCCTCTCGGTCGGGGTGAACTTTGGGCTTTTTCTCAATATTA
TCCGCATCCTGGTGAGGAAACTGGAGCCAGCTCAGGGCAGCCTCCATACCCAGTCTCAGTATTGGCGTCTCTCCAAGTCGACACTTTTCC
TGATCCCACTCTTTGGAATTCACTACATCATCTTCAACTTCCTGCCAGACAATGCTGGCCTGGGCATCCGCCTCCCCCTGGAGCTGGGAC
TGGGTTCCTTCCAGGGCTTCATTGTTGCCATCCTCTACTGCTTCCTCAACCAAGAGGTGAGGACTGAGATCTCACGGAAGTGGCATGGCC
ATGACCCTGAGCTTCTGCCAGCCTGGAGGACCCGTGCTAAGTGGACCACGCCTTCCCGCTCGGCGGCAAAGGTGCTGACATCTATGTGCT
AGGCTGCCTCATCACGCCACTGGAGTCCACACTTGAATTTGGGCAGCTACCACGGGTCTGCCATGCTCTGGAGGAGCAAGGGGGCCACAT
CCCCACCCCAGCTGTTACCCAGCCCGGGGCAGGTGCAGCCCTTCCTCCCTGTCTCTGCATCTGACTCTCTTTTGAGGTCCCTGTATGTCT
ACCTCTGACTTCTGTGGTCCCTCTGTGTCTGCTCTCATCCATTCCTCTTACTGGGGCCTGGGGCTCTAGCCCAAGGCTCAGAGGAGCCAA
TAAACCTGTAAATGAA

>2281_2281_7_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31132349_ENST00000409489_GHRHR_chr7_31014586_ENST00000326139_length(amino acids)=501AA_BP=111
MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVW
ETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYT
IIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLCWDLDDTSPYW
WIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGSFQGFIV
AILYCFLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKVLTSMC

--------------------------------------------------------------
>2281_2281_8_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31132349_ENST00000409489_GHRHR_chr7_31014586_ENST00000409904_length(transcript)=1807nt_BP=1072nt
GCCAGTGGTGCTGGCCAAGAAGTGTCATGGCTGGTGTCGTGCACGTTTCCCTGGCTGCTCTCCTCCTGCTGCCTATGGCCCCTGCCATGC
ATTCTGACTGCATCTTCAAGAAGGAGCAAGCCATGTGCCTGGAGAAGATCCAGAGGGCCAATGAGCTGATGGGCTTCAATGATTCCTCTC
CAGGCTGTCCTGGGATGTGGGACAACATCACGTGTTGGAAGCCCGCCCATGTGGGTGAGATGGTCCTGGTCAGCTGCCCTGAGCTCTTCC
GAATCTTCAACCCAGACCAAGTCTGGGAGACCGAAACCATTGGAGAGTCTGATTTTGGTGACAGTAACTCCTTAGATCTCTCAGACATGG
GAGTGGTGAGCCGGAACTGCACGGAGGATGGCTGGTCGGAACCCTTCCCTCATTACTTTGATGCCTGTGGGTTTGATGAATATGAATCTG
AGACTGGGGACCAGGATTATTACTACCTGTCAGTGAAGGCCCTCTACACGGTTGGCTACAGCACATCCCTCGTCACCCTCACCACTGCCA
TGGTCATCCTTTGTCGCTTCCGGAAGCTGCACTGCACACGCAACTTCATCCACATGAACCTGTTTGTGTCGTTCATGCTGAGGGCGATCT
CCGTCTTCATCAAAGACTGGATTCTGTATGCGGAGCAGGACAGCAACCACTGCTTCATCTCCACTGTGGAATGTAAGGCCGTCATGGTTT
TCTTCCACTACTGTGTTGTGTCCAACTACTTCTGGCTGTTCATCGAGGGCCTGTACCTCTTCACTCTGCTGGTGGAGACCTTCTTCCCTG
AAAGGAGATACTTCTACTGGTACACCATCATTGGCTGGGGGACCCCAACTGTGTGTGTGACAGTGTGGGCTACGCTGAGACTCTACTTTG
ATGACACAGGCTGCTGGGATATGAATGACAGCACAGCTCTGTGGTGGGTGATCAAAGGCCCTGTGGTTGGCTCTATCATGGTTAACTTTG
TGCTTTTTATTGGCATTATCGTCATCCTTGTGCAGAAACTTCAGTCTCCAGACATGGGAGGCAATGAGTCCAGCATCTACTTGTGCTGGG
ACCTGGACGACACCTCCCCCTACTGGTGGATCATCAAAGGGCCCATTGTCCTCTCGGTCGGGGTGAACTTTGGGCTTTTTCTCAATATTA
TCCGCATCCTGGTGAGGAAACTGGAGCCAGCTCAGGGCAGCCTCCATACCCAGTCTCAGTATTGGCGTCTCTCCAAGTCGACACTTTTCC
TGATCCCACTCTTTGGAATTCACTACATCATCTTCAACTTCCTGCCAGACAATGCTGGCCTGGGCATCCGCCTCCCCCTGGAGCTGGGAC
TGGGTTCCTTCCAGGGCTTCATTGTTGCCATCCTCTACTGCTTCCTCAACCAAGAGGTGAGGACTGAGATCTCACGGAAGTGGCATGGCC
ATGACCCTGAGCTTCTGCCAGCCTGGAGGACCCGTGCTAAGTGGACCACGCCTTCCCGCTCGGCGGCAAAGGTGCTGACATCTATGTGCT
AGGCTGCCTCATCACGCCACTGGAGTCCACACTTGAATTTGGGCAGCTACCACGGGTCTGCCATGCTCTGGAGGAGCAAGGGGGCCACAT
CCCCACCCCAGCTGTTACCCAGCCCGGGGCAGGTGCAGCCCTTCCTCCCTGTCTCTGCATCTGACTCTCTTTTGAGGTCCCTGTATGTCT
ACCTCTGACTTCTGTGGTCCCTCTGTGTCTGCTCTCATCCATTCCTCTTACTGGGGCCTGGGGCTCTAGCCCAAGGCTCAGAGGAGCCAA
TAAACCT

>2281_2281_8_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31132349_ENST00000409489_GHRHR_chr7_31014586_ENST00000409904_length(amino acids)=501AA_BP=111
MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVW
ETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYT
IIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLCWDLDDTSPYW
WIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGSFQGFIV
AILYCFLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKVLTSMC

--------------------------------------------------------------
>2281_2281_9_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31139824_ENST00000396211_GHRHR_chr7_31014586_ENST00000326139_length(transcript)=1945nt_BP=1201nt
CCCAGAGACACATTGGGGCTGACCTGCCGCTGCTGTCAGTGGGAGGCCAGTGGTGCTGGCCAAGAAGTGTCATGGCTGGTGTCGTGCACG
TTTCCCTGGCTGCTCTCCTCCTGCTGCCTATGGCCCCTGCCATGCATTCTGACTGCATCTTCAAGAAGGAGCAAGCCATGTGCCTGGAGA
AGATCCAGAGGGCCAATGAGCTGATGGGCTTCAATGATTCCTCTCCAGGCTGTCCTGGGATGTGGGACAACATCACGTGTTGGAAGCCCG
CCCATGTGGGTGAGATGGTCCTGGTCAGCTGCCCTGAGCTCTTCCGAATCTTCAACCCAGACCAAGTCTGGGAGACCGAAACCATTGGAG
AGTCTGATTTTGGTGACAGTAACTCCTTAGATCTCTCAGACATGGGAGTGGTGAGCCGGAACTGCACGGAGGATGGCTGGTCGGAACCCT
TCCCTCATTACTTTGATGCCTGTGGGTTTGATGAATATGAATCTGAGACTGGGGACCAGGATTATTACTACCTGTCAGTGAAGGCCCTCT
ACACGGTTGGCTACAGCACATCCCTCGTCACCCTCACCACTGCCATGGTCATCCTTTGTCGCTTCCGGAAGCTGCACTGCACACGCAACT
TCATCCACATGAACCTGTTTGTGTCGTTCATGCTGAGGGCGATCTCCGTCTTCATCAAAGACTGGATTCTGTATGCGGAGCAGGACAGCA
ACCACTGCTTCATCTCCACTGTGGAATGTAAGGCCGTCATGGTTTTCTTCCACTACTGTGTTGTGTCCAACTACTTCTGGCTGTTCATCG
AGGGCCTGTACCTCTTCACTCTGCTGGTGGAGACCTTCTTCCCTGAAAGGAGATACTTCTACTGGTACACCATCATTGGCTGGGGGACCC
CAACTGTGTGTGTGACAGTGTGGGCTACGCTGAGACTCTACTTTGATGACACAGGCTGCTGGGATATGAATGACAGCACAGCTCTGTGGT
GGGTGATCAAAGGCCCTGTGGTTGGCTCTATCATGGTTAACTTTGTGCTTTTTATTGGCATTATCGTCATCCTTGTGCAGAAACTTCAGT
CTCCAGACATGGGAGGCAATGAGTCCAGCATCTACTTCAGCTGCGTGCAGAAATGCTACTGCAAGCCACAGCGGGCTCAGCAGCACTCTT
GCAAGATGTCAGAACTGTCCACCATTACTCTGTGCTGGGACCTGGACGACACCTCCCCCTACTGGTGGATCATCAAAGGGCCCATTGTCC
TCTCGGTCGGGGTGAACTTTGGGCTTTTTCTCAATATTATCCGCATCCTGGTGAGGAAACTGGAGCCAGCTCAGGGCAGCCTCCATACCC
AGTCTCAGTATTGGCGTCTCTCCAAGTCGACACTTTTCCTGATCCCACTCTTTGGAATTCACTACATCATCTTCAACTTCCTGCCAGACA
ATGCTGGCCTGGGCATCCGCCTCCCCCTGGAGCTGGGACTGGGTTCCTTCCAGGGCTTCATTGTTGCCATCCTCTACTGCTTCCTCAACC
AAGAGGTGAGGACTGAGATCTCACGGAAGTGGCATGGCCATGACCCTGAGCTTCTGCCAGCCTGGAGGACCCGTGCTAAGTGGACCACGC
CTTCCCGCTCGGCGGCAAAGGTGCTGACATCTATGTGCTAGGCTGCCTCATCACGCCACTGGAGTCCACACTTGAATTTGGGCAGCTACC
ACGGGTCTGCCATGCTCTGGAGGAGCAAGGGGGCCACATCCCCACCCCAGCTGTTACCCAGCCCGGGGCAGGTGCAGCCCTTCCTCCCTG
TCTCTGCATCTGACTCTCTTTTGAGGTCCCTGTATGTCTACCTCTGACTTCTGTGGTCCCTCTGTGTCTGCTCTCATCCATTCCTCTTAC
TGGGGCCTGGGGCTCTAGCCCAAGGCTCAGAGGAGCCAATAAACCTGTAAATGAA

>2281_2281_9_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31139824_ENST00000396211_GHRHR_chr7_31014586_ENST00000326139_length(amino acids)=545AA_BP=127
MPLLSVGGQWCWPRSVMAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVL
VSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTS
LVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTL
LVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNE
SSIYFSCVQKCYCKPQRAQQHSCKMSELSTITLCWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLS
KSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKV
LTSMC

--------------------------------------------------------------
>2281_2281_10_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31139824_ENST00000396211_GHRHR_chr7_31014586_ENST00000409904_length(transcript)=1936nt_BP=1201nt
CCCAGAGACACATTGGGGCTGACCTGCCGCTGCTGTCAGTGGGAGGCCAGTGGTGCTGGCCAAGAAGTGTCATGGCTGGTGTCGTGCACG
TTTCCCTGGCTGCTCTCCTCCTGCTGCCTATGGCCCCTGCCATGCATTCTGACTGCATCTTCAAGAAGGAGCAAGCCATGTGCCTGGAGA
AGATCCAGAGGGCCAATGAGCTGATGGGCTTCAATGATTCCTCTCCAGGCTGTCCTGGGATGTGGGACAACATCACGTGTTGGAAGCCCG
CCCATGTGGGTGAGATGGTCCTGGTCAGCTGCCCTGAGCTCTTCCGAATCTTCAACCCAGACCAAGTCTGGGAGACCGAAACCATTGGAG
AGTCTGATTTTGGTGACAGTAACTCCTTAGATCTCTCAGACATGGGAGTGGTGAGCCGGAACTGCACGGAGGATGGCTGGTCGGAACCCT
TCCCTCATTACTTTGATGCCTGTGGGTTTGATGAATATGAATCTGAGACTGGGGACCAGGATTATTACTACCTGTCAGTGAAGGCCCTCT
ACACGGTTGGCTACAGCACATCCCTCGTCACCCTCACCACTGCCATGGTCATCCTTTGTCGCTTCCGGAAGCTGCACTGCACACGCAACT
TCATCCACATGAACCTGTTTGTGTCGTTCATGCTGAGGGCGATCTCCGTCTTCATCAAAGACTGGATTCTGTATGCGGAGCAGGACAGCA
ACCACTGCTTCATCTCCACTGTGGAATGTAAGGCCGTCATGGTTTTCTTCCACTACTGTGTTGTGTCCAACTACTTCTGGCTGTTCATCG
AGGGCCTGTACCTCTTCACTCTGCTGGTGGAGACCTTCTTCCCTGAAAGGAGATACTTCTACTGGTACACCATCATTGGCTGGGGGACCC
CAACTGTGTGTGTGACAGTGTGGGCTACGCTGAGACTCTACTTTGATGACACAGGCTGCTGGGATATGAATGACAGCACAGCTCTGTGGT
GGGTGATCAAAGGCCCTGTGGTTGGCTCTATCATGGTTAACTTTGTGCTTTTTATTGGCATTATCGTCATCCTTGTGCAGAAACTTCAGT
CTCCAGACATGGGAGGCAATGAGTCCAGCATCTACTTCAGCTGCGTGCAGAAATGCTACTGCAAGCCACAGCGGGCTCAGCAGCACTCTT
GCAAGATGTCAGAACTGTCCACCATTACTCTGTGCTGGGACCTGGACGACACCTCCCCCTACTGGTGGATCATCAAAGGGCCCATTGTCC
TCTCGGTCGGGGTGAACTTTGGGCTTTTTCTCAATATTATCCGCATCCTGGTGAGGAAACTGGAGCCAGCTCAGGGCAGCCTCCATACCC
AGTCTCAGTATTGGCGTCTCTCCAAGTCGACACTTTTCCTGATCCCACTCTTTGGAATTCACTACATCATCTTCAACTTCCTGCCAGACA
ATGCTGGCCTGGGCATCCGCCTCCCCCTGGAGCTGGGACTGGGTTCCTTCCAGGGCTTCATTGTTGCCATCCTCTACTGCTTCCTCAACC
AAGAGGTGAGGACTGAGATCTCACGGAAGTGGCATGGCCATGACCCTGAGCTTCTGCCAGCCTGGAGGACCCGTGCTAAGTGGACCACGC
CTTCCCGCTCGGCGGCAAAGGTGCTGACATCTATGTGCTAGGCTGCCTCATCACGCCACTGGAGTCCACACTTGAATTTGGGCAGCTACC
ACGGGTCTGCCATGCTCTGGAGGAGCAAGGGGGCCACATCCCCACCCCAGCTGTTACCCAGCCCGGGGCAGGTGCAGCCCTTCCTCCCTG
TCTCTGCATCTGACTCTCTTTTGAGGTCCCTGTATGTCTACCTCTGACTTCTGTGGTCCCTCTGTGTCTGCTCTCATCCATTCCTCTTAC
TGGGGCCTGGGGCTCTAGCCCAAGGCTCAGAGGAGCCAATAAACCT

>2281_2281_10_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31139824_ENST00000396211_GHRHR_chr7_31014586_ENST00000409904_length(amino acids)=545AA_BP=127
MPLLSVGGQWCWPRSVMAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVL
VSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTS
LVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTL
LVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNE
SSIYFSCVQKCYCKPQRAQQHSCKMSELSTITLCWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLS
KSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKV
LTSMC

--------------------------------------------------------------
>2281_2281_11_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31139824_ENST00000409489_GHRHR_chr7_31014586_ENST00000326139_length(transcript)=1984nt_BP=1240nt
GCCAGTGGTGCTGGCCAAGAAGTGTCATGGCTGGTGTCGTGCACGTTTCCCTGGCTGCTCTCCTCCTGCTGCCTATGGCCCCTGCCATGC
ATTCTGACTGCATCTTCAAGAAGGAGCAAGCCATGTGCCTGGAGAAGATCCAGAGGGCCAATGAGCTGATGGGCTTCAATGATTCCTCTC
CAGGCTGTCCTGGGATGTGGGACAACATCACGTGTTGGAAGCCCGCCCATGTGGGTGAGATGGTCCTGGTCAGCTGCCCTGAGCTCTTCC
GAATCTTCAACCCAGACCAAGTCTGGGAGACCGAAACCATTGGAGAGTCTGATTTTGGTGACAGTAACTCCTTAGATCTCTCAGACATGG
GAGTGGTGAGCCGGAACTGCACGGAGGATGGCTGGTCGGAACCCTTCCCTCATTACTTTGATGCCTGTGGGTTTGATGAATATGAATCTG
AGACTGGGGACCAGGATTATTACTACCTGTCAGTGAAGGCCCTCTACACGGTTGGCTACAGCACATCCCTCGTCACCCTCACCACTGCCA
TGGTCATCCTTTGTCGCTTCCGGAAGCTGCACTGCACACGCAACTTCATCCACATGAACCTGTTTGTGTCGTTCATGCTGAGGGCGATCT
CCGTCTTCATCAAAGACTGGATTCTGTATGCGGAGCAGGACAGCAACCACTGCTTCATCTCCACTGTGGAATGTAAGGCCGTCATGGTTT
TCTTCCACTACTGTGTTGTGTCCAACTACTTCTGGCTGTTCATCGAGGGCCTGTACCTCTTCACTCTGCTGGTGGAGACCTTCTTCCCTG
AAAGGAGATACTTCTACTGGTACACCATCATTGGCTGGGGGACCCCAACTGTGTGTGTGACAGTGTGGGCTACGCTGAGACTCTACTTTG
ATGACACAGGCTGCTGGGATATGAATGACAGCACAGCTCTGTGGTGGGTGATCAAAGGCCCTGTGGTTGGCTCTATCATGGTTAACTTTG
TGCTTTTTATTGGCATTATCGTCATCCTTGTGCAGAAACTTCAGTCTCCAGACATGGGAGGCAATGAGTCCAGCATCTACTTAACAAATT
TAAGCCCGCGAGTCCCCAAGAAAGCCCGAGAGGACCCCCTGCCTGTGCCCTCAGACCAGCATTCACTCCCTTTCCTCAGCTGCGTGCAGA
AATGCTACTGCAAGCCACAGCGGGCTCAGCAGCACTCTTGCAAGATGTCAGAACTGTCCACCATTACTCTGTGCTGGGACCTGGACGACA
CCTCCCCCTACTGGTGGATCATCAAAGGGCCCATTGTCCTCTCGGTCGGGGTGAACTTTGGGCTTTTTCTCAATATTATCCGCATCCTGG
TGAGGAAACTGGAGCCAGCTCAGGGCAGCCTCCATACCCAGTCTCAGTATTGGCGTCTCTCCAAGTCGACACTTTTCCTGATCCCACTCT
TTGGAATTCACTACATCATCTTCAACTTCCTGCCAGACAATGCTGGCCTGGGCATCCGCCTCCCCCTGGAGCTGGGACTGGGTTCCTTCC
AGGGCTTCATTGTTGCCATCCTCTACTGCTTCCTCAACCAAGAGGTGAGGACTGAGATCTCACGGAAGTGGCATGGCCATGACCCTGAGC
TTCTGCCAGCCTGGAGGACCCGTGCTAAGTGGACCACGCCTTCCCGCTCGGCGGCAAAGGTGCTGACATCTATGTGCTAGGCTGCCTCAT
CACGCCACTGGAGTCCACACTTGAATTTGGGCAGCTACCACGGGTCTGCCATGCTCTGGAGGAGCAAGGGGGCCACATCCCCACCCCAGC
TGTTACCCAGCCCGGGGCAGGTGCAGCCCTTCCTCCCTGTCTCTGCATCTGACTCTCTTTTGAGGTCCCTGTATGTCTACCTCTGACTTC
TGTGGTCCCTCTGTGTCTGCTCTCATCCATTCCTCTTACTGGGGCCTGGGGCTCTAGCCCAAGGCTCAGAGGAGCCAATAAACCTGTAAA
TGAA

>2281_2281_11_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31139824_ENST00000409489_GHRHR_chr7_31014586_ENST00000326139_length(amino acids)=557AA_BP=111
MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVW
ETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYT
IIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLTNLSPRVPKKA
REDPLPVPSDQHSLPFLSCVQKCYCKPQRAQQHSCKMSELSTITLCWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQG
SLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRTRA
KWTTPSRSAAKVLTSMC

--------------------------------------------------------------
>2281_2281_12_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31139824_ENST00000409489_GHRHR_chr7_31014586_ENST00000409904_length(transcript)=1975nt_BP=1240nt
GCCAGTGGTGCTGGCCAAGAAGTGTCATGGCTGGTGTCGTGCACGTTTCCCTGGCTGCTCTCCTCCTGCTGCCTATGGCCCCTGCCATGC
ATTCTGACTGCATCTTCAAGAAGGAGCAAGCCATGTGCCTGGAGAAGATCCAGAGGGCCAATGAGCTGATGGGCTTCAATGATTCCTCTC
CAGGCTGTCCTGGGATGTGGGACAACATCACGTGTTGGAAGCCCGCCCATGTGGGTGAGATGGTCCTGGTCAGCTGCCCTGAGCTCTTCC
GAATCTTCAACCCAGACCAAGTCTGGGAGACCGAAACCATTGGAGAGTCTGATTTTGGTGACAGTAACTCCTTAGATCTCTCAGACATGG
GAGTGGTGAGCCGGAACTGCACGGAGGATGGCTGGTCGGAACCCTTCCCTCATTACTTTGATGCCTGTGGGTTTGATGAATATGAATCTG
AGACTGGGGACCAGGATTATTACTACCTGTCAGTGAAGGCCCTCTACACGGTTGGCTACAGCACATCCCTCGTCACCCTCACCACTGCCA
TGGTCATCCTTTGTCGCTTCCGGAAGCTGCACTGCACACGCAACTTCATCCACATGAACCTGTTTGTGTCGTTCATGCTGAGGGCGATCT
CCGTCTTCATCAAAGACTGGATTCTGTATGCGGAGCAGGACAGCAACCACTGCTTCATCTCCACTGTGGAATGTAAGGCCGTCATGGTTT
TCTTCCACTACTGTGTTGTGTCCAACTACTTCTGGCTGTTCATCGAGGGCCTGTACCTCTTCACTCTGCTGGTGGAGACCTTCTTCCCTG
AAAGGAGATACTTCTACTGGTACACCATCATTGGCTGGGGGACCCCAACTGTGTGTGTGACAGTGTGGGCTACGCTGAGACTCTACTTTG
ATGACACAGGCTGCTGGGATATGAATGACAGCACAGCTCTGTGGTGGGTGATCAAAGGCCCTGTGGTTGGCTCTATCATGGTTAACTTTG
TGCTTTTTATTGGCATTATCGTCATCCTTGTGCAGAAACTTCAGTCTCCAGACATGGGAGGCAATGAGTCCAGCATCTACTTAACAAATT
TAAGCCCGCGAGTCCCCAAGAAAGCCCGAGAGGACCCCCTGCCTGTGCCCTCAGACCAGCATTCACTCCCTTTCCTCAGCTGCGTGCAGA
AATGCTACTGCAAGCCACAGCGGGCTCAGCAGCACTCTTGCAAGATGTCAGAACTGTCCACCATTACTCTGTGCTGGGACCTGGACGACA
CCTCCCCCTACTGGTGGATCATCAAAGGGCCCATTGTCCTCTCGGTCGGGGTGAACTTTGGGCTTTTTCTCAATATTATCCGCATCCTGG
TGAGGAAACTGGAGCCAGCTCAGGGCAGCCTCCATACCCAGTCTCAGTATTGGCGTCTCTCCAAGTCGACACTTTTCCTGATCCCACTCT
TTGGAATTCACTACATCATCTTCAACTTCCTGCCAGACAATGCTGGCCTGGGCATCCGCCTCCCCCTGGAGCTGGGACTGGGTTCCTTCC
AGGGCTTCATTGTTGCCATCCTCTACTGCTTCCTCAACCAAGAGGTGAGGACTGAGATCTCACGGAAGTGGCATGGCCATGACCCTGAGC
TTCTGCCAGCCTGGAGGACCCGTGCTAAGTGGACCACGCCTTCCCGCTCGGCGGCAAAGGTGCTGACATCTATGTGCTAGGCTGCCTCAT
CACGCCACTGGAGTCCACACTTGAATTTGGGCAGCTACCACGGGTCTGCCATGCTCTGGAGGAGCAAGGGGGCCACATCCCCACCCCAGC
TGTTACCCAGCCCGGGGCAGGTGCAGCCCTTCCTCCCTGTCTCTGCATCTGACTCTCTTTTGAGGTCCCTGTATGTCTACCTCTGACTTC
TGTGGTCCCTCTGTGTCTGCTCTCATCCATTCCTCTTACTGGGGCCTGGGGCTCTAGCCCAAGGCTCAGAGGAGCCAATAAACCT

>2281_2281_12_ADCYAP1R1-GHRHR_ADCYAP1R1_chr7_31139824_ENST00000409489_GHRHR_chr7_31014586_ENST00000409904_length(amino acids)=557AA_BP=111
MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVW
ETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYT
IIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLTNLSPRVPKKA
REDPLPVPSDQHSLPFLSCVQKCYCKPQRAQQHSCKMSELSTITLCWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQG
SLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRTRA
KWTTPSRSAAKVLTSMC

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ADCYAP1R1-GHRHR


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ADCYAP1R1-GHRHR


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ADCYAP1R1-GHRHR


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneADCYAP1R1C0004096Asthma1CTD_human
HgeneADCYAP1R1C0036341Schizophrenia1PSYGENET
TgeneC4722273ISOLATED GROWTH HORMONE DEFICIENCY, TYPE IV5GENOMICS_ENGLAND;UNIPROT
TgeneC2748571Isolated Growth Hormone Deficiency, Type IB2ORPHANET