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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CLCN3-UBE2D3 (FusionGDB2 ID:HG1182TG7323)

Fusion Gene Summary for CLCN3-UBE2D3

check button Fusion gene summary
Fusion gene informationFusion gene name: CLCN3-UBE2D3
Fusion gene ID: hg1182tg7323
HgeneTgene
Gene symbol

CLCN3

UBE2D3

Gene ID

1182

7323

Gene namechloride voltage-gated channel 3ubiquitin conjugating enzyme E2 D3
SynonymsCLC3|ClC-3E2(17)KB3|UBC4/5|UBCH5C
Cytomap('CLCN3')('UBE2D3')

4q33

4q24

Type of geneprotein-codingprotein-coding
DescriptionH(+)/Cl(-) exchange transporter 3chloride channel 3chloride channel protein 3chloride channel, voltage-sensitive 3chloride transporter ClC-3ubiquitin-conjugating enzyme E2 D3(E3-independent) E2 ubiquitin-conjugating enzyme D3E2 ubiquitin-conjugating enzyme D3ubiquitin carrier protein D3ubiquitin conjugating enzyme E2D 3ubiquitin-conjugating enzyme E2(17)KB 3ubiquitin-conjugating enzyme
Modification date2020031320200313
UniProtAcc

P51790

.
Ensembl transtripts involved in fusion geneENST00000506924, ENST00000347613, 
ENST00000360642, ENST00000504131, 
ENST00000513761, 
Fusion gene scores* DoF score13 X 9 X 6=7028 X 5 X 7=280
# samples 169
** MAII scorelog2(16/702*10)=-2.1333991254172
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/280*10)=-1.63742992061529
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CLCN3 [Title/Abstract] AND UBE2D3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCLCN3(170557239)-UBE2D3(103731012), # samples:4
Anticipated loss of major functional domain due to fusion event.CLCN3-UBE2D3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CLCN3-UBE2D3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CLCN3-UBE2D3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CLCN3-UBE2D3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CLCN3-UBE2D3 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
CLCN3-UBE2D3 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
CLCN3-UBE2D3 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCLCN3

GO:1902476

chloride transmembrane transport

11274166

TgeneUBE2D3

GO:0000209

protein polyubiquitination

14765125|16522193

TgeneUBE2D3

GO:0006513

protein monoubiquitination

20347421

TgeneUBE2D3

GO:0016567

protein ubiquitination

9990509|21532592

TgeneUBE2D3

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

20347421

TgeneUBE2D3

GO:0051865

protein autoubiquitination

21068390

TgeneUBE2D3

GO:0070936

protein K48-linked ubiquitination

20061386

TgeneUBE2D3

GO:0070979

protein K11-linked ubiquitination

20061386


check buttonFusion gene breakpoints across CLCN3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across UBE2D3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AR-A2LR-01ACLCN3chr4

170557239

-UBE2D3chr4

103731012

-
ChimerDB4BRCATCGA-AR-A2LR-01ACLCN3chr4

170557239

+UBE2D3chr4

103731012

-
ChimerDB4BRCATCGA-AR-A2LRCLCN3chr4

170557239

+UBE2D3chr4

103731012

-


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Fusion Gene ORF analysis for CLCN3-UBE2D3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000506924ENST00000321805CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
3UTR-3CDSENST00000506924ENST00000338145CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
3UTR-3CDSENST00000506924ENST00000343106CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
3UTR-3CDSENST00000506924ENST00000349311CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
3UTR-3CDSENST00000506924ENST00000350435CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
3UTR-3CDSENST00000506924ENST00000394801CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
3UTR-3CDSENST00000506924ENST00000394803CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
3UTR-3CDSENST00000506924ENST00000394804CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
3UTR-3CDSENST00000506924ENST00000453744CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
3UTR-5UTRENST00000506924ENST00000357194CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
3UTR-5UTRENST00000506924ENST00000502404CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
3UTR-5UTRENST00000506924ENST00000504211CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
3UTR-5UTRENST00000506924ENST00000505207CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
3UTR-5UTRENST00000506924ENST00000507845CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
3UTR-5UTRENST00000506924ENST00000513098CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000347613ENST00000357194CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000347613ENST00000502404CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000347613ENST00000504211CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000347613ENST00000505207CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000347613ENST00000507845CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000347613ENST00000513098CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000360642ENST00000357194CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000360642ENST00000502404CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000360642ENST00000504211CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000360642ENST00000505207CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000360642ENST00000507845CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000360642ENST00000513098CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000504131ENST00000357194CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000504131ENST00000502404CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000504131ENST00000504211CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000504131ENST00000505207CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000504131ENST00000507845CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000504131ENST00000513098CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000513761ENST00000357194CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000513761ENST00000502404CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000513761ENST00000504211CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000513761ENST00000505207CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000513761ENST00000507845CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
5CDS-5UTRENST00000513761ENST00000513098CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000347613ENST00000321805CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000347613ENST00000338145CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000347613ENST00000343106CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000347613ENST00000349311CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000347613ENST00000350435CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000347613ENST00000394801CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000347613ENST00000394803CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000347613ENST00000394804CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000347613ENST00000453744CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000360642ENST00000321805CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000360642ENST00000338145CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000360642ENST00000343106CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000360642ENST00000349311CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000360642ENST00000350435CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000360642ENST00000394801CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000360642ENST00000394803CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000360642ENST00000394804CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000360642ENST00000453744CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000513761ENST00000321805CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000513761ENST00000338145CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000513761ENST00000343106CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000513761ENST00000349311CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000513761ENST00000350435CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000513761ENST00000394801CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000513761ENST00000394803CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000513761ENST00000394804CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
Frame-shiftENST00000513761ENST00000453744CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
In-frameENST00000504131ENST00000321805CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
In-frameENST00000504131ENST00000338145CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
In-frameENST00000504131ENST00000343106CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
In-frameENST00000504131ENST00000349311CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
In-frameENST00000504131ENST00000350435CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
In-frameENST00000504131ENST00000394801CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
In-frameENST00000504131ENST00000394803CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
In-frameENST00000504131ENST00000394804CLCN3chr4

170557239

+UBE2D3chr4

103731012

-
In-frameENST00000504131ENST00000453744CLCN3chr4

170557239

+UBE2D3chr4

103731012

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000504131CLCN3chr4170557239+ENST00000453744UBE2D3chr4103731012-3855403385822145
ENST00000504131CLCN3chr4170557239+ENST00000394801UBE2D3chr4103731012-2262403385822145
ENST00000504131CLCN3chr4170557239+ENST00000394803UBE2D3chr4103731012-2262403385822145
ENST00000504131CLCN3chr4170557239+ENST00000394804UBE2D3chr4103731012-2261403385822145
ENST00000504131CLCN3chr4170557239+ENST00000343106UBE2D3chr4103731012-2154403385825146
ENST00000504131CLCN3chr4170557239+ENST00000321805UBE2D3chr4103731012-1003403385822145
ENST00000504131CLCN3chr4170557239+ENST00000350435UBE2D3chr4103731012-991403385822145
ENST00000504131CLCN3chr4170557239+ENST00000338145UBE2D3chr4103731012-986403385822145
ENST00000504131CLCN3chr4170557239+ENST00000349311UBE2D3chr4103731012-974403385822145

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000504131ENST00000453744CLCN3chr4170557239+UBE2D3chr4103731012-0.0108548470.9891452
ENST00000504131ENST00000394801CLCN3chr4170557239+UBE2D3chr4103731012-0.0208134780.97918653
ENST00000504131ENST00000394803CLCN3chr4170557239+UBE2D3chr4103731012-0.0208134780.97918653
ENST00000504131ENST00000394804CLCN3chr4170557239+UBE2D3chr4103731012-0.02081050.9791895
ENST00000504131ENST00000343106CLCN3chr4170557239+UBE2D3chr4103731012-0.0133270030.986673
ENST00000504131ENST00000321805CLCN3chr4170557239+UBE2D3chr4103731012-0.0148780040.98512197
ENST00000504131ENST00000350435CLCN3chr4170557239+UBE2D3chr4103731012-0.0151549840.984845
ENST00000504131ENST00000338145CLCN3chr4170557239+UBE2D3chr4103731012-0.0158340330.984166
ENST00000504131ENST00000349311CLCN3chr4170557239+UBE2D3chr4103731012-0.016406580.9835934

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Fusion Genomic Features for CLCN3-UBE2D3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for CLCN3-UBE2D3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:170557239/chr4:103731012)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CLCN3

P51790

.
FUNCTION: [Isoform 1]: Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons (By similarity). The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons (PubMed:29845874). The presence of conserved gating glutamate residues is typical for family members that function as antiporters (PubMed:29845874). {ECO:0000250|UniProtKB:P51791, ECO:0000303|PubMed:29845874}.; FUNCTION: [Isoform 2]: Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons. {ECO:0000269|PubMed:11967229}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+21428_2953867.0MotifDi-leucine internalization motif%3B mediates targeting to late endosome and lysosome membranes
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+21446_4753867.0MotifDi-leucine internalization motif%3B mediates targeting to late endosome and lysosome membranes
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+21228_2953792.0MotifDi-leucine internalization motif%3B mediates targeting to late endosome and lysosome membranes
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+21246_4753792.0MotifDi-leucine internalization motif%3B mediates targeting to late endosome and lysosome membranes
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+21328_2953819.0MotifDi-leucine internalization motif%3B mediates targeting to late endosome and lysosome membranes
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+21346_4753819.0MotifDi-leucine internalization motif%3B mediates targeting to late endosome and lysosome membranes

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214658_72253867.0DomainCBS 1
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214755_81253867.0DomainCBS 2
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212658_72253792.0DomainCBS 1
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212755_81253792.0DomainCBS 2
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213658_72253819.0DomainCBS 1
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213755_81253819.0DomainCBS 2
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214241_24853867.0IntramembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214313_32553867.0IntramembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214329_33753867.0IntramembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214572_58653867.0IntramembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214590_60153867.0IntramembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214602_60553867.0IntramembraneNote%3DLoop between two helices
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212241_24853792.0IntramembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212313_32553792.0IntramembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212329_33753792.0IntramembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212572_58653792.0IntramembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212590_60153792.0IntramembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212602_60553792.0IntramembraneNote%3DLoop between two helices
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213241_24853819.0IntramembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213313_32553819.0IntramembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213329_33753819.0IntramembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213572_58653819.0IntramembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213590_60153819.0IntramembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213602_60553819.0IntramembraneNote%3DLoop between two helices
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214238_24253867.0MotifSelectivity filter part_1
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214280_28453867.0MotifSelectivity filter part_2
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214525_52953867.0MotifSelectivity filter part_3
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+21471_7553867.0MotifDi-leucine internalization motif%3B mediates targeting to late endosome and lysosome membranes
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212238_24253792.0MotifSelectivity filter part_1
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212280_28453792.0MotifSelectivity filter part_2
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212525_52953792.0MotifSelectivity filter part_3
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+21271_7553792.0MotifDi-leucine internalization motif%3B mediates targeting to late endosome and lysosome membranes
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213238_24253819.0MotifSelectivity filter part_1
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213280_28453819.0MotifSelectivity filter part_2
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213525_52953819.0MotifSelectivity filter part_3
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+21371_7553819.0MotifDi-leucine internalization motif%3B mediates targeting to late endosome and lysosome membranes
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214689_69153867.0Nucleotide bindingATP
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214796_79953867.0Nucleotide bindingATP
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212689_69153792.0Nucleotide bindingATP
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212796_79953792.0Nucleotide bindingATP
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213689_69153819.0Nucleotide bindingATP
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213796_79953819.0Nucleotide bindingATP
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+2141_12553867.0Topological domainCytoplasmic
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214625_81853867.0Topological domainCytoplasmic
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+2121_12553792.0Topological domainCytoplasmic
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212625_81853792.0Topological domainCytoplasmic
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+2131_12553819.0Topological domainCytoplasmic
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213625_81853819.0Topological domainCytoplasmic
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214126_16353867.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214209_23253867.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214258_27653867.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214282_30153867.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214349_36753867.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214391_41653867.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214423_44353867.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214500_52053867.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214525_54453867.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000347613+214606_62453867.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212126_16353792.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212209_23253792.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212258_27653792.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212282_30153792.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212349_36753792.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212391_41653792.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212423_44353792.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212500_52053792.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212525_54453792.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000360642+212606_62453792.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213126_16353819.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213209_23253819.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213258_27653819.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213282_30153819.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213349_36753819.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213391_41653819.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213423_44353819.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213500_52053819.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213525_54453819.0TransmembraneHelical
HgeneCLCN3chr4:170557239chr4:103731012ENST00000513761+213606_62453819.0TransmembraneHelical
TgeneUBE2D3chr4:170557239chr4:103731012ENST00000321805181_1478148.0DomainUBC core
TgeneUBE2D3chr4:170557239chr4:103731012ENST00000338145181_1478148.0DomainUBC core
TgeneUBE2D3chr4:170557239chr4:103731012ENST00000343106081_1478374.0DomainUBC core
TgeneUBE2D3chr4:170557239chr4:103731012ENST00000349311181_1478148.0DomainUBC core
TgeneUBE2D3chr4:170557239chr4:103731012ENST00000357194071_14710150.0DomainUBC core
TgeneUBE2D3chr4:170557239chr4:103731012ENST00000394801181_1478148.0DomainUBC core
TgeneUBE2D3chr4:170557239chr4:103731012ENST00000394803181_1478148.0DomainUBC core
TgeneUBE2D3chr4:170557239chr4:103731012ENST00000394804181_1478148.0DomainUBC core
TgeneUBE2D3chr4:170557239chr4:103731012ENST00000453744181_1478148.0DomainUBC core


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Fusion Gene Sequence for CLCN3-UBE2D3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>16992_16992_1_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000321805_length(transcript)=1003nt_BP=403nt
TTGCTCCCGTGTTTGAAGGAGGACAATAAAAGTCCCACCGGGCAAAATTTTCGTAACCTCTGCGGTAGAAAACGTCAGGTATCTTTTAAA
TCGCGATAGTTTTCGCTGTGTCAGGCTTTCTTCGGTGGAGCTCCGAGGGTAGCTAGGTTCTAGGTTTGAAACAGATGCAGAATCCAAAGG
CAGCGCAAAAAACAGCCACCGATTTTGCTATGTCTCTGAGCTGCGAGATAATCAGACAGCTAAATGGAGTCTGAGCAGCTGTTCCATAGA
GGCTACTATAGAAACAGCTACAACAGTATAACAAGTGCAAGTAGTGATGAGGAACTTTTAGATGGAGCAGGTGTTATTATGGACTTTCAA
ACATCTGAAGATGACAATTTATTAGATGGTGACACTGCAGTTGGAACTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGG
TCCAGTTGGGGATGATATGTTTCATTGGCAAGCCACAATTATGGGACCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAAT
TCATTTTCCTACAGACTACCCCTTCAAACCACCTAAGGTTGCATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCAT
TTGTCTCGATATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATTTCTAAAGTTCTTTTATCCATTTGTTCACTGCTATGTGATCCAAA
CCCAGATGACCCCCTAGTGCCAGAGATTGCACGGATCTATAAAACAGACAGAGATAAGTACAACAGAATATCTCGGGAATGGACTCAGAA
GTATGCCATGTGATGCTACCTTAAAGTCAGAATAACCTGCATTATAGCTGGAATAAACTTTAAATTACTGTTCCTTTTTTGATTTTCTTA
TCCGGCTGCTCCCCTATCAGACCTCATCTTTTTTAATTTTATTTTTTGTTTACCTCCCTCCATTCATTCACATGCTCATCTGAGAAGACT
TAAGTTCTTCCAG

>16992_16992_1_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000321805_length(amino acids)=145AA_BP=6
MVTLQLELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ
WSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM

--------------------------------------------------------------
>16992_16992_2_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000338145_length(transcript)=986nt_BP=403nt
TTGCTCCCGTGTTTGAAGGAGGACAATAAAAGTCCCACCGGGCAAAATTTTCGTAACCTCTGCGGTAGAAAACGTCAGGTATCTTTTAAA
TCGCGATAGTTTTCGCTGTGTCAGGCTTTCTTCGGTGGAGCTCCGAGGGTAGCTAGGTTCTAGGTTTGAAACAGATGCAGAATCCAAAGG
CAGCGCAAAAAACAGCCACCGATTTTGCTATGTCTCTGAGCTGCGAGATAATCAGACAGCTAAATGGAGTCTGAGCAGCTGTTCCATAGA
GGCTACTATAGAAACAGCTACAACAGTATAACAAGTGCAAGTAGTGATGAGGAACTTTTAGATGGAGCAGGTGTTATTATGGACTTTCAA
ACATCTGAAGATGACAATTTATTAGATGGTGACACTGCAGTTGGAACTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGG
TCCAGTTGGGGATGATATGTTTCATTGGCAAGCCACAATTATGGGACCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAAT
TCATTTTCCTACAGACTACCCCTTCAAACCACCTAAGGTTGCATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCAT
TTGTCTCGATATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATTTCTAAAGTTCTTTTATCCATTTGTTCACTGCTATGTGATCCAAA
CCCAGATGACCCCCTAGTGCCAGAGATTGCACGGATCTATAAAACAGACAGAGATAAGTACAACAGAATATCTCGGGAATGGACTCAGAA
GTATGCCATGTGATGCTACCTTAAAGTCAGAATAACCTGCATTATAGCTGGAATAAACTTTAAATTACTGTTCCTTTTTTGATTTTCTTA
TCCGGCTGCTCCCCTATCAGACCTCATCTTTTTTAATTTTATTTTTTGTTTACCTCCCTCCATTCATTCACATGCTCATCTGAGAA

>16992_16992_2_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000338145_length(amino acids)=145AA_BP=6
MVTLQLELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ
WSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM

--------------------------------------------------------------
>16992_16992_3_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000343106_length(transcript)=2154nt_BP=403nt
TTGCTCCCGTGTTTGAAGGAGGACAATAAAAGTCCCACCGGGCAAAATTTTCGTAACCTCTGCGGTAGAAAACGTCAGGTATCTTTTAAA
TCGCGATAGTTTTCGCTGTGTCAGGCTTTCTTCGGTGGAGCTCCGAGGGTAGCTAGGTTCTAGGTTTGAAACAGATGCAGAATCCAAAGG
CAGCGCAAAAAACAGCCACCGATTTTGCTATGTCTCTGAGCTGCGAGATAATCAGACAGCTAAATGGAGTCTGAGCAGCTGTTCCATAGA
GGCTACTATAGAAACAGCTACAACAGTATAACAAGTGCAAGTAGTGATGAGGAACTTTTAGATGGAGCAGGTGTTATTATGGACTTTCAA
ACATCTGAAGATGACAATTTATTAGATGGTGACACTGCAGTTGGAACTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGG
TCCAGTTGGGGATGATATGTTTCATTGGCAAGCCACAATTATGGGACCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAAT
TCATTTTCCTACAGACTACCCCTTCAAACCACCTAAGGTTGCATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCAT
TTGTCTCGATATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATTTCTAAAGTTCTTTTATCCATTTGTTCACTGCTATGTGATCCAAA
CCCAGATGACCCCCTAGTGCCAGAGATTGCACGGATCTATAAAACAGACAGAGATAAGTACAATAGGTTAGCAAGAGAGTGGACAGAGAA
ATACGCTATGTTGTAGGGTACAACAGAATATCTCGGGAATGGACTCAGAAGTATGCCATGTGATGCTACCTTAAAGTCAGAATAACCTGC
ATTATAGCTGGAATAAACTTTAAATTACTGTTCCTTTTTTGATTTTCTTATCCGGCTGCTCCCCTATCAGACCTCATCTTTTTTAATTTT
ATTTTTTGTTTACCTCCCTCCATTCATTCACATGCTCATCTGAGAAGACTTAAGTTCTTCCAGCTTTGGACAATAACTGCTTTTAGAAAC
TGTAAAGTAGTTACAAGAGAACAGTTGCCCAAGACTCAGAATTTTTAAAAAAAAAAATGGAGCATGTGTATTATGTGGCCAATGTCTTCA
CTCTAACTTGGTTATGAGACTAAAACCATTCCTCACTGCTCTAACATGCTGAAGAAATCATCTGAGGGGGAGGGAGATGGATGCTCAGTT
GTCACATCAAAGGATACAGCATTATTCTAGCAGCATCCATTCTTGTTTAAGCCTTCCACTGTTAGAGATTTGAGGTTACATGATATGCTT
TATGCTCATAACTGATGTGGCTGGAGAATTGGTATTGAATTTATAGCATCAGCAGAACAGAAAATGTGATGTATTTTATGCATGTCAATA
AAGGAATGACCTGTTCTTGTTCTACAGAGAATGGAAATTGGAAGTCAAACACCCTTTGTATTCCAAAATAGGGTCTCAAACATTTTGTAA
TTTTCATTTAAATTGTTAGGAGGCTTGGAGCTATTAGTTAATCTATCTTCCAATACACTGTTTAATATAGCACTGAATAAATGATGCAAG
TTGTCAATGGATGAGTGATCAACTAATAGCTCTGCTAGTAATTGATTTATTTTTCTTCAATAAAGTTGCATAAACCAATGAGTTAGCTGC
CTGGATTAATCAGTATGGGAAACAATCTTTTGTAAATGCAAAGCTGTTTTTTGTATATACTGTTGGGATTTGCTTCATTGTTTGACATCA
AATGATGATGTAAAGTTCGAAAGAGTGAATATTTTGCCATGTTCAGTTAAAGTGCACAGTCTGTTACAGGTTGACACATTGCTTGACCTG
ATTTATGCAGAATTAATAAGCTATTTGGATAGTGTAGCTTTAATGTGCTGCACATGATACTGGCAGCCCTAGAGTTCATAGATGGACTTT
TGGGACCCAGCAGTTTTGAAATGTGTTTATGGAGTTTAAGAAATTTATTTTCCAGGTGCAGCCCCTGTCTAACTGAAATTTCTCTTCACC
TTGTACACTTGACAGCTGAAAAAAAACAACATGGGAGTAATAATGGGTCAAAATTTGCAAAATAAAGTACTGTTTTGGTGTGGG

>16992_16992_3_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000343106_length(amino acids)=146AA_BP=6
MVTLQLELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ
WSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRLAREWTEKYAML

--------------------------------------------------------------
>16992_16992_4_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000349311_length(transcript)=974nt_BP=403nt
TTGCTCCCGTGTTTGAAGGAGGACAATAAAAGTCCCACCGGGCAAAATTTTCGTAACCTCTGCGGTAGAAAACGTCAGGTATCTTTTAAA
TCGCGATAGTTTTCGCTGTGTCAGGCTTTCTTCGGTGGAGCTCCGAGGGTAGCTAGGTTCTAGGTTTGAAACAGATGCAGAATCCAAAGG
CAGCGCAAAAAACAGCCACCGATTTTGCTATGTCTCTGAGCTGCGAGATAATCAGACAGCTAAATGGAGTCTGAGCAGCTGTTCCATAGA
GGCTACTATAGAAACAGCTACAACAGTATAACAAGTGCAAGTAGTGATGAGGAACTTTTAGATGGAGCAGGTGTTATTATGGACTTTCAA
ACATCTGAAGATGACAATTTATTAGATGGTGACACTGCAGTTGGAACTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGG
TCCAGTTGGGGATGATATGTTTCATTGGCAAGCCACAATTATGGGACCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAAT
TCATTTTCCTACAGACTACCCCTTCAAACCACCTAAGGTTGCATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCAT
TTGTCTCGATATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATTTCTAAAGTTCTTTTATCCATTTGTTCACTGCTATGTGATCCAAA
CCCAGATGACCCCCTAGTGCCAGAGATTGCACGGATCTATAAAACAGACAGAGATAAGTACAACAGAATATCTCGGGAATGGACTCAGAA
GTATGCCATGTGATGCTACCTTAAAGTCAGAATAACCTGCATTATAGCTGGAATAAACTTTAAATTACTGTTCCTTTTTTGATTTTCTTA
TCCGGCTGCTCCCCTATCAGACCTCATCTTTTTTAATTTTATTTTTTGTTTACCTCCCTCCATTCATTCACATG

>16992_16992_4_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000349311_length(amino acids)=145AA_BP=6
MVTLQLELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ
WSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM

--------------------------------------------------------------
>16992_16992_5_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000350435_length(transcript)=991nt_BP=403nt
TTGCTCCCGTGTTTGAAGGAGGACAATAAAAGTCCCACCGGGCAAAATTTTCGTAACCTCTGCGGTAGAAAACGTCAGGTATCTTTTAAA
TCGCGATAGTTTTCGCTGTGTCAGGCTTTCTTCGGTGGAGCTCCGAGGGTAGCTAGGTTCTAGGTTTGAAACAGATGCAGAATCCAAAGG
CAGCGCAAAAAACAGCCACCGATTTTGCTATGTCTCTGAGCTGCGAGATAATCAGACAGCTAAATGGAGTCTGAGCAGCTGTTCCATAGA
GGCTACTATAGAAACAGCTACAACAGTATAACAAGTGCAAGTAGTGATGAGGAACTTTTAGATGGAGCAGGTGTTATTATGGACTTTCAA
ACATCTGAAGATGACAATTTATTAGATGGTGACACTGCAGTTGGAACTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGG
TCCAGTTGGGGATGATATGTTTCATTGGCAAGCCACAATTATGGGACCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAAT
TCATTTTCCTACAGACTACCCCTTCAAACCACCTAAGGTTGCATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCAT
TTGTCTCGATATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATTTCTAAAGTTCTTTTATCCATTTGTTCACTGCTATGTGATCCAAA
CCCAGATGACCCCCTAGTGCCAGAGATTGCACGGATCTATAAAACAGACAGAGATAAGTACAACAGAATATCTCGGGAATGGACTCAGAA
GTATGCCATGTGATGCTACCTTAAAGTCAGAATAACCTGCATTATAGCTGGAATAAACTTTAAATTACTGTTCCTTTTTTGATTTTCTTA
TCCGGCTGCTCCCCTATCAGACCTCATCTTTTTTAATTTTATTTTTTGTTTACCTCCCTCCATTCATTCACATGCTCATCTGAGAAGACT
T

>16992_16992_5_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000350435_length(amino acids)=145AA_BP=6
MVTLQLELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ
WSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM

--------------------------------------------------------------
>16992_16992_6_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000394801_length(transcript)=2262nt_BP=403nt
TTGCTCCCGTGTTTGAAGGAGGACAATAAAAGTCCCACCGGGCAAAATTTTCGTAACCTCTGCGGTAGAAAACGTCAGGTATCTTTTAAA
TCGCGATAGTTTTCGCTGTGTCAGGCTTTCTTCGGTGGAGCTCCGAGGGTAGCTAGGTTCTAGGTTTGAAACAGATGCAGAATCCAAAGG
CAGCGCAAAAAACAGCCACCGATTTTGCTATGTCTCTGAGCTGCGAGATAATCAGACAGCTAAATGGAGTCTGAGCAGCTGTTCCATAGA
GGCTACTATAGAAACAGCTACAACAGTATAACAAGTGCAAGTAGTGATGAGGAACTTTTAGATGGAGCAGGTGTTATTATGGACTTTCAA
ACATCTGAAGATGACAATTTATTAGATGGTGACACTGCAGTTGGAACTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGG
TCCAGTTGGGGATGATATGTTTCATTGGCAAGCCACAATTATGGGACCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAAT
TCATTTTCCTACAGACTACCCCTTCAAACCACCTAAGGTTGCATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCAT
TTGTCTCGATATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATTTCTAAAGTTCTTTTATCCATTTGTTCACTGCTATGTGATCCAAA
CCCAGATGACCCCCTAGTGCCAGAGATTGCACGGATCTATAAAACAGACAGAGATAAGTACAACAGAATATCTCGGGAATGGACTCAGAA
GTATGCCATGTGATGCTACCTTAAAGTCAGAATAACCTGCATTATAGCTGGAATAAACTTTAAATTACTGTTCCTTTTTTGATTTTCTTA
TCCGGCTGCTCCCCTATCAGACCTCATCTTTTTTAATTTTATTTTTTGTTTACCTCCCTCCATTCATTCACATGCTCATCTGAGAAGACT
TAAGTTCTTCCAGCTTTGGACAATAACTGCTTTTAGAAACTGTAAAGTAGTTACAAGAGAACAGTTGCCCAAGACTCAGAATTTTTAAAA
AAAAAAATGGAGCATGTGTATTATGTGGCCAATGTCTTCACTCTAACTTGGTTATGAGACTAAAACCATTCCTCACTGCTCTAACATGCT
GAAGAAATCATCTGAGGGGGAGGGAGATGGATGCTCAGTTGTCACATCAAAGGATACAGCATTATTCTAGCAGCATCCATTCTTGTTTAA
GCCTTCCACTGTTAGAGATTTGAGGTTACATGATATGCTTTATGCTCATAACTGATGTGGCTGGAGAATTGGTATTGAATTTATAGCATC
AGCAGAACAGAAAATGTGATGTATTTTATGCATGTCAATAAAGGAATGACCTGTTCTTGTTCTACAGAGAATGGAAATTGGAAGTCAAAC
ACCCTTTGTATTCCAAAATAGGGTCTCAAACATTTTGTAATTTTCATTTAAATTGTTAGGAGGCTTGGAGCTATTAGTTAATCTATCTTC
CAATACACTGTTTAATATAGCACTGAATAAATGATGCAAGTTGTCAATGGATGAGTGATCAACTAATAGCTCTGCTAGTAATTGATTTAT
TTTTCTTCAATAAAGTTGCATAAACCAATGAGTTAGCTGCCTGGATTAATCAGTATGGGAAACAATCTTTTGTAAATGCAAAGCTGTTTT
TTGTATATACTGTTGGGATTTGCTTCATTGTTTGACATCAAATGATGATGTAAAGTTCGAAAGAGTGAATATTTTGCCATGTTCAGTTAA
AGTGCACAGTCTGTTACAGGTTGACACATTGCTTGACCTGATTTATGCAGAATTAATAAGCTATTTGGATAGTGTAGCTTTAATGTGCTG
CACATGATACTGGCAGCCCTAGAGTTCATAGATGGACTTTTGGGACCCAGCAGTTTTGAAATGTGTTTATGGAGTTTAAGAAATTTATTT
TCCAGGTGCAGCCCCTGTCTAACTGAAATTTCTCTTCACCTTGTACACTTGACAGCTGAAAAAAAACAACATGGGAGTAATAATGGGTCA
AAATTTGCAAAATAAAGTACTGTTTTGGTGTGGGAGTTGTCATGAGGCTGTGTTGAAGTGACTTATCTATGTGGGATATTGAGTATCCAT
TGAAATGGATTTGTTCAGCCATTTACATTAATGAGCATTTAAATGCAACAGATATCATTTCAGGTGACTTAACATGAATGAATAAAAGTC
AATGCTATTGGA

>16992_16992_6_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000394801_length(amino acids)=145AA_BP=6
MVTLQLELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ
WSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM

--------------------------------------------------------------
>16992_16992_7_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000394803_length(transcript)=2262nt_BP=403nt
TTGCTCCCGTGTTTGAAGGAGGACAATAAAAGTCCCACCGGGCAAAATTTTCGTAACCTCTGCGGTAGAAAACGTCAGGTATCTTTTAAA
TCGCGATAGTTTTCGCTGTGTCAGGCTTTCTTCGGTGGAGCTCCGAGGGTAGCTAGGTTCTAGGTTTGAAACAGATGCAGAATCCAAAGG
CAGCGCAAAAAACAGCCACCGATTTTGCTATGTCTCTGAGCTGCGAGATAATCAGACAGCTAAATGGAGTCTGAGCAGCTGTTCCATAGA
GGCTACTATAGAAACAGCTACAACAGTATAACAAGTGCAAGTAGTGATGAGGAACTTTTAGATGGAGCAGGTGTTATTATGGACTTTCAA
ACATCTGAAGATGACAATTTATTAGATGGTGACACTGCAGTTGGAACTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGG
TCCAGTTGGGGATGATATGTTTCATTGGCAAGCCACAATTATGGGACCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAAT
TCATTTTCCTACAGACTACCCCTTCAAACCACCTAAGGTTGCATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCAT
TTGTCTCGATATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATTTCTAAAGTTCTTTTATCCATTTGTTCACTGCTATGTGATCCAAA
CCCAGATGACCCCCTAGTGCCAGAGATTGCACGGATCTATAAAACAGACAGAGATAAGTACAACAGAATATCTCGGGAATGGACTCAGAA
GTATGCCATGTGATGCTACCTTAAAGTCAGAATAACCTGCATTATAGCTGGAATAAACTTTAAATTACTGTTCCTTTTTTGATTTTCTTA
TCCGGCTGCTCCCCTATCAGACCTCATCTTTTTTAATTTTATTTTTTGTTTACCTCCCTCCATTCATTCACATGCTCATCTGAGAAGACT
TAAGTTCTTCCAGCTTTGGACAATAACTGCTTTTAGAAACTGTAAAGTAGTTACAAGAGAACAGTTGCCCAAGACTCAGAATTTTTAAAA
AAAAAAATGGAGCATGTGTATTATGTGGCCAATGTCTTCACTCTAACTTGGTTATGAGACTAAAACCATTCCTCACTGCTCTAACATGCT
GAAGAAATCATCTGAGGGGGAGGGAGATGGATGCTCAGTTGTCACATCAAAGGATACAGCATTATTCTAGCAGCATCCATTCTTGTTTAA
GCCTTCCACTGTTAGAGATTTGAGGTTACATGATATGCTTTATGCTCATAACTGATGTGGCTGGAGAATTGGTATTGAATTTATAGCATC
AGCAGAACAGAAAATGTGATGTATTTTATGCATGTCAATAAAGGAATGACCTGTTCTTGTTCTACAGAGAATGGAAATTGGAAGTCAAAC
ACCCTTTGTATTCCAAAATAGGGTCTCAAACATTTTGTAATTTTCATTTAAATTGTTAGGAGGCTTGGAGCTATTAGTTAATCTATCTTC
CAATACACTGTTTAATATAGCACTGAATAAATGATGCAAGTTGTCAATGGATGAGTGATCAACTAATAGCTCTGCTAGTAATTGATTTAT
TTTTCTTCAATAAAGTTGCATAAACCAATGAGTTAGCTGCCTGGATTAATCAGTATGGGAAACAATCTTTTGTAAATGCAAAGCTGTTTT
TTGTATATACTGTTGGGATTTGCTTCATTGTTTGACATCAAATGATGATGTAAAGTTCGAAAGAGTGAATATTTTGCCATGTTCAGTTAA
AGTGCACAGTCTGTTACAGGTTGACACATTGCTTGACCTGATTTATGCAGAATTAATAAGCTATTTGGATAGTGTAGCTTTAATGTGCTG
CACATGATACTGGCAGCCCTAGAGTTCATAGATGGACTTTTGGGACCCAGCAGTTTTGAAATGTGTTTATGGAGTTTAAGAAATTTATTT
TCCAGGTGCAGCCCCTGTCTAACTGAAATTTCTCTTCACCTTGTACACTTGACAGCTGAAAAAAAACAACATGGGAGTAATAATGGGTCA
AAATTTGCAAAATAAAGTACTGTTTTGGTGTGGGAGTTGTCATGAGGCTGTGTTGAAGTGACTTATCTATGTGGGATATTGAGTATCCAT
TGAAATGGATTTGTTCAGCCATTTACATTAATGAGCATTTAAATGCAACAGATATCATTTCAGGTGACTTAACATGAATGAATAAAAGTC
AATGCTATTGGA

>16992_16992_7_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000394803_length(amino acids)=145AA_BP=6
MVTLQLELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ
WSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM

--------------------------------------------------------------
>16992_16992_8_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000394804_length(transcript)=2261nt_BP=403nt
TTGCTCCCGTGTTTGAAGGAGGACAATAAAAGTCCCACCGGGCAAAATTTTCGTAACCTCTGCGGTAGAAAACGTCAGGTATCTTTTAAA
TCGCGATAGTTTTCGCTGTGTCAGGCTTTCTTCGGTGGAGCTCCGAGGGTAGCTAGGTTCTAGGTTTGAAACAGATGCAGAATCCAAAGG
CAGCGCAAAAAACAGCCACCGATTTTGCTATGTCTCTGAGCTGCGAGATAATCAGACAGCTAAATGGAGTCTGAGCAGCTGTTCCATAGA
GGCTACTATAGAAACAGCTACAACAGTATAACAAGTGCAAGTAGTGATGAGGAACTTTTAGATGGAGCAGGTGTTATTATGGACTTTCAA
ACATCTGAAGATGACAATTTATTAGATGGTGACACTGCAGTTGGAACTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGG
TCCAGTTGGGGATGATATGTTTCATTGGCAAGCCACAATTATGGGACCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAAT
TCATTTTCCTACAGACTACCCCTTCAAACCACCTAAGGTTGCATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCAT
TTGTCTCGATATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATTTCTAAAGTTCTTTTATCCATTTGTTCACTGCTATGTGATCCAAA
CCCAGATGACCCCCTAGTGCCAGAGATTGCACGGATCTATAAAACAGACAGAGATAAGTACAACAGAATATCTCGGGAATGGACTCAGAA
GTATGCCATGTGATGCTACCTTAAAGTCAGAATAACCTGCATTATAGCTGGAATAAACTTTAAATTACTGTTCCTTTTTTGATTTTCTTA
TCCGGCTGCTCCCCTATCAGACCTCATCTTTTTTAATTTTATTTTTTGTTTACCTCCCTCCATTCATTCACATGCTCATCTGAGAAGACT
TAAGTTCTTCCAGCTTTGGACAATAACTGCTTTTAGAAACTGTAAAGTAGTTACAAGAGAACAGTTGCCCAAGACTCAGAATTTTTAAAA
AAAAAAATGGAGCATGTGTATTATGTGGCCAATGTCTTCACTCTAACTTGGTTATGAGACTAAAACCATTCCTCACTGCTCTAACATGCT
GAAGAAATCATCTGAGGGGGAGGGAGATGGATGCTCAGTTGTCACATCAAAGGATACAGCATTATTCTAGCAGCATCCATTCTTGTTTAA
GCCTTCCACTGTTAGAGATTTGAGGTTACATGATATGCTTTATGCTCATAACTGATGTGGCTGGAGAATTGGTATTGAATTTATAGCATC
AGCAGAACAGAAAATGTGATGTATTTTATGCATGTCAATAAAGGAATGACCTGTTCTTGTTCTACAGAGAATGGAAATTGGAAGTCAAAC
ACCCTTTGTATTCCAAAATAGGGTCTCAAACATTTTGTAATTTTCATTTAAATTGTTAGGAGGCTTGGAGCTATTAGTTAATCTATCTTC
CAATACACTGTTTAATATAGCACTGAATAAATGATGCAAGTTGTCAATGGATGAGTGATCAACTAATAGCTCTGCTAGTAATTGATTTAT
TTTTCTTCAATAAAGTTGCATAAACCAATGAGTTAGCTGCCTGGATTAATCAGTATGGGAAACAATCTTTTGTAAATGCAAAGCTGTTTT
TTGTATATACTGTTGGGATTTGCTTCATTGTTTGACATCAAATGATGATGTAAAGTTCGAAAGAGTGAATATTTTGCCATGTTCAGTTAA
AGTGCACAGTCTGTTACAGGTTGACACATTGCTTGACCTGATTTATGCAGAATTAATAAGCTATTTGGATAGTGTAGCTTTAATGTGCTG
CACATGATACTGGCAGCCCTAGAGTTCATAGATGGACTTTTGGGACCCAGCAGTTTTGAAATGTGTTTATGGAGTTTAAGAAATTTATTT
TCCAGGTGCAGCCCCTGTCTAACTGAAATTTCTCTTCACCTTGTACACTTGACAGCTGAAAAAAAACAACATGGGAGTAATAATGGGTCA
AAATTTGCAAAATAAAGTACTGTTTTGGTGTGGGAGTTGTCATGAGGCTGTGTTGAAGTGACTTATCTATGTGGGATATTGAGTATCCAT
TGAAATGGATTTGTTCAGCCATTTACATTAATGAGCATTTAAATGCAACAGATATCATTTCAGGTGACTTAACATGAATGAATAAAAGTC
AATGCTATTGG

>16992_16992_8_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000394804_length(amino acids)=145AA_BP=6
MVTLQLELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ
WSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM

--------------------------------------------------------------
>16992_16992_9_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000453744_length(transcript)=3855nt_BP=403nt
TTGCTCCCGTGTTTGAAGGAGGACAATAAAAGTCCCACCGGGCAAAATTTTCGTAACCTCTGCGGTAGAAAACGTCAGGTATCTTTTAAA
TCGCGATAGTTTTCGCTGTGTCAGGCTTTCTTCGGTGGAGCTCCGAGGGTAGCTAGGTTCTAGGTTTGAAACAGATGCAGAATCCAAAGG
CAGCGCAAAAAACAGCCACCGATTTTGCTATGTCTCTGAGCTGCGAGATAATCAGACAGCTAAATGGAGTCTGAGCAGCTGTTCCATAGA
GGCTACTATAGAAACAGCTACAACAGTATAACAAGTGCAAGTAGTGATGAGGAACTTTTAGATGGAGCAGGTGTTATTATGGACTTTCAA
ACATCTGAAGATGACAATTTATTAGATGGTGACACTGCAGTTGGAACTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGG
TCCAGTTGGGGATGATATGTTTCATTGGCAAGCCACAATTATGGGACCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAAT
TCATTTTCCTACAGACTACCCCTTCAAACCACCTAAGGTTGCATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCAT
TTGTCTCGATATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATTTCTAAAGTTCTTTTATCCATTTGTTCACTGCTATGTGATCCAAA
CCCAGATGACCCCCTAGTGCCAGAGATTGCACGGATCTATAAAACAGACAGAGATAAGTACAACAGAATATCTCGGGAATGGACTCAGAA
GTATGCCATGTGATGCTACCTTAAAGTCAGAATAACCTGCATTATAGCTGGAATAAACTTTAAATTACTGTTCCTTTTTTGATTTTCTTA
TCCGGCTGCTCCCCTATCAGACCTCATCTTTTTTAATTTTATTTTTTGTTTACCTCCCTCCATTCATTCACATGCTCATCTGAGAAGACT
TAAGTTCTTCCAGCTTTGGACAATAACTGCTTTTAGAAACTGTAAAGTAGTTACAAGAGAACAGTTGCCCAAGACTCAGAATTTTTAAAA
AAAAAAATGGAGCATGTGTATTATGTGGCCAATGTCTTCACTCTAACTTGGTTATGAGACTAAAACCATTCCTCACTGCTCTAACATGCT
GAAGAAATCATCTGAGGGGGAGGGAGATGGATGCTCAGTTGTCACATCAAAGGATACAGCATTATTCTAGCAGCATCCATTCTTGTTTAA
GCCTTCCACTGTTAGAGATTTGAGGTTACATGATATGCTTTATGCTCATAACTGATGTGGCTGGAGAATTGGTATTGAATTTATAGCATC
AGCAGAACAGAAAATGTGATGTATTTTATGCATGTCAATAAAGGAATGACCTGTTCTTGTTCTACAGAGAATGGAAATTGGAAGTCAAAC
ACCCTTTGTATTCCAAAATAGGGTCTCAAACATTTTGTAATTTTCATTTAAATTGTTAGGAGGCTTGGAGCTATTAGTTAATCTATCTTC
CAATACACTGTTTAATATAGCACTGAATAAATGATGCAAGTTGTCAATGGATGAGTGATCAACTAATAGCTCTGCTAGTAATTGATTTAT
TTTTCTTCAATAAAGTTGCATAAACCAATGAGTTAGCTGCCTGGATTAATCAGTATGGGAAACAATCTTTTGTAAATGCAAAGCTGTTTT
TTGTATATACTGTTGGGATTTGCTTCATTGTTTGACATCAAATGATGATGTAAAGTTCGAAAGAGTGAATATTTTGCCATGTTCAGTTAA
AGTGCACAGTCTGTTACAGGTTGACACATTGCTTGACCTGATTTATGCAGAATTAATAAGCTATTTGGATAGTGTAGCTTTAATGTGCTG
CACATGATACTGGCAGCCCTAGAGTTCATAGATGGACTTTTGGGACCCAGCAGTTTTGAAATGTGTTTATGGAGTTTAAGAAATTTATTT
TCCAGGTGCAGCCCCTGTCTAACTGAAATTTCTCTTCACCTTGTACACTTGACAGCTGAAAAAAAACAACATGGGAGTAATAATGGGTCA
AAATTTGCAAAATAAAGTACTGTTTTGGTGTGGGAGTTGTCATGAGGCTGTGTTGAAGTGACTTATCTATGTGGGATATTGAGTATCCAT
TGAAATGGATTTGTTCAGCCATTTACATTAATGAGCATTTAAATGCAACAGATATCATTTCAGGTGACTTAACATGAATGAATAAAAGTC
AATGCTATTGGATTGTTTTTTGTTTGACAAGTGCTATCTGTGCCACTGATTTAACTTCTGTAGTAACAAGGGCATTACCATTCTTCACCT
TTCCTAATTCTGATCCCATAGTTTTACATTTTTCCTGTTTATTTTGATTTTGTTCACTGCTTTATTTCTTAAAGTTCTAGCACATCTGTG
ACTCCTCCACTTCCACATTTTTGCACTGCTTACACTTACGTGCAATCTTATTCCTTGTCTGCACACACATGTGGAAAGCTAGAAATAAAT
GTTAAAACTTACTTTTTATAAACATTTTAATATGTAGTTTGGACATGATTTATTGACTTAAGGTTCTTCTCTAAACTGGAAGTGAAATGC
ATGCCTTCTGAAGATGTTCTGGCTTTGTTAATTCTGTAATCATTTCATTGGGGAAAAAACCAGCTACGCAGTTTTTCCAATGAGTGAATT
TTTTCATTTTGTGTTTTGCTTAAAACGGCTCCTTCAGGGTAGATGTCATACTGCATAACTTTTTTGGATTCAAATTATGAATGAGAAATT
AGTTAACATTCTGCTCCACAAGGTAAGAAAAACTGCTCTTTGGCTCTATTTTCAAAATTACTTCTGAGATGCATATAGTCTCAAAATAAC
AGCTTTAGTAGGCATATCACTTCTTGAAAGCCAAACATGAGTGTAAGACACTTTTATGAAACACGGTGGATCCCTAACTGGCTTTCAAAT
TGACCTTTATAGCCTTAGACAACCCTTAGGTATTTACGGAGATGACTTCTTTGATTGTCATAACAATTAGTGGATGTGTCCAGTTCTCTG
TATCTTTGACTTGATGCTTTATACATCATTTCATTTGTTGCTTCTAAGGGAATAAGCCATAGAGGCTTCTCCAGGTTTAAAAGAACAGTA
AAGTACCTGGAAAACCAACATTTTTGAATGTATGGACACTGGACATGAGATATGTACAATGAAATCTTAAAAGAATCTAAGAATTTGCCC
TCTTTGCCCCACTCCACCCAGTAATTTGACATTACTAGTGCCATGTATAGGACCCAACTGAGTATTAGAATCAGTTTTGACTATGTCTTT
GTATTTCCTAAATCTTTTAATGCATAAACCGAATTAGGGTCCAGTTGGCCTGTTAATGGTAAATTTACATTTTAAATGACTCAGTTTGTT
TTTCCTGGGCGAGTTTGCAATGTGATAATCAGATTTTTTAAAACTGATTAATTTGCTTTCTTGTGTGGGTGTACTCACATTTTAAAGTAT
GAACCACAGTTAACTAGTGGTCTCAGGGGTAGTGAAACACTCACTTTTTTTTTTGTTTGTTTTTTTTTGTTTGTTGAAATGGCTTAGTTG
AAGTATACTTAAGGTACTGATCATGCTGTGTTAGTAATTTGGGCGGGGAGGGGGGTAACTCAGCCATGTTTTGTGTTGGCATAACAAAAC
TGTTAATGATTGTTGATTACACTTTTAAGTGAATTTGTCTTTTATGAGGAACCCAGTGCAAGTCACTAAATATTGTCTAATAGTGACATC
TGCATAAGACTTGTAATAGCTGAAGTTAATTGAGCTTAAAGGAATTGTTACCATTAAAGTCTGTGTTTAAAGACA

>16992_16992_9_CLCN3-UBE2D3_CLCN3_chr4_170557239_ENST00000504131_UBE2D3_chr4_103731012_ENST00000453744_length(amino acids)=145AA_BP=6
MVTLQLELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ
WSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CLCN3-UBE2D3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CLCN3-UBE2D3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CLCN3-UBE2D3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCLCN3C0017638Glioma1CTD_human
HgeneCLCN3C0024623Malignant neoplasm of stomach1CTD_human
HgeneCLCN3C0038356Stomach Neoplasms1CTD_human
HgeneCLCN3C0235874Disease Exacerbation1CTD_human
HgeneCLCN3C0259783mixed gliomas1CTD_human
HgeneCLCN3C0555198Malignant Glioma1CTD_human
HgeneCLCN3C1708349Hereditary Diffuse Gastric Cancer1CTD_human
HgeneCLCN3C2931822Nasopharyngeal carcinoma1CTD_human