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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:CLN3-C15orf32 (FusionGDB2 ID:HG1201TG145858)

Fusion Gene Summary for CLN3-C15orf32

check button Fusion gene summary
Fusion gene informationFusion gene name: CLN3-C15orf32
Fusion gene ID: hg1201tg145858
HgeneTgene
Gene symbol

CLN3

C15orf32

Gene ID

1201

145858

Gene nameCLN3 lysosomal/endosomal transmembrane protein, batteninchromosome 15 putative open reading frame 32
SynonymsBTN1|BTS|JNCL-
Cytomap('CLN3')('C15orf32')

16p12.1

15q26.1

Type of geneprotein-codingncRNA
DescriptionbatteninCLN3, batteninbatten disease proteinceroid-lipofuscinosis, neuronal 3uncharacterized protein C15orf32
Modification date2020032820200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000333496, ENST00000354630, 
ENST00000355477, ENST00000357806, 
ENST00000357857, ENST00000359984, 
ENST00000360019, ENST00000395653, 
ENST00000535392, ENST00000565316, 
ENST00000567963, ENST00000568224, 
ENST00000569430, ENST00000357076, 
ENST00000567160, 
Fusion gene scores* DoF score5 X 4 X 3=602 X 2 X 2=8
# samples 52
** MAII scorelog2(5/60*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(2/8*10)=1.32192809488736
Context

PubMed: CLN3 [Title/Abstract] AND C15orf32 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCLN3(28495327)-C15orf32(93043588), # samples:4
Anticipated loss of major functional domain due to fusion event.CLN3-C15orf32 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CLN3-C15orf32 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CLN3-C15orf32 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCLN3

GO:0015809

arginine transport

16251196

HgeneCLN3

GO:0035752

lysosomal lumen pH elevation

10924275

HgeneCLN3

GO:0042987

amyloid precursor protein catabolic process

10924275


check buttonFusion gene breakpoints across CLN3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across C15orf32 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4HNSCTCGA-CR-5247-01ACLN3chr16

28495327

-C15orf32chr15

93043588

+
ChimerDB4HNSCTCGA-CR-5247CLN3chr16

28495327

-C15orf32chr15

93043588

+


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Fusion Gene ORF analysis for CLN3-C15orf32

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000333496ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000354630ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000355477ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000357806ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000357857ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000359984ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000360019ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000395653ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000535392ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000565316ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000567963ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000568224ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000569430ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
Frame-shiftENST00000357806ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
Frame-shiftENST00000357857ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
Frame-shiftENST00000359984ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
Frame-shiftENST00000395653ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
Frame-shiftENST00000565316ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
Frame-shiftENST00000569430ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
In-frameENST00000333496ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
In-frameENST00000354630ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
In-frameENST00000355477ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
In-frameENST00000360019ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
In-frameENST00000535392ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
In-frameENST00000567963ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
In-frameENST00000568224ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
intron-3CDSENST00000357076ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
intron-3CDSENST00000567160ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
intron-3UTRENST00000357076ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
intron-3UTRENST00000567160ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000568224CLN3chr1628495327-ENST00000333334C15orf32chr1593043588+1652892261902213
ENST00000535392CLN3chr1628495327-ENST00000333334C15orf32chr1593043588+1652892261902213
ENST00000360019CLN3chr1628495327-ENST00000333334C15orf32chr1593043588+190911493591159266
ENST00000333496CLN3chr1628495327-ENST00000333334C15orf32chr1593043588+157781799827242
ENST00000355477CLN3chr1628495327-ENST00000333334C15orf32chr1593043588+1523763117773218
ENST00000354630CLN3chr1628495327-ENST00000333334C15orf32chr1593043588+1667907117917266
ENST00000567963CLN3chr1628495327-ENST00000333334C15orf32chr1593043588+1662902112912266

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000568224ENST00000333334CLN3chr1628495327-C15orf32chr1593043588+0.202640560.79735947
ENST00000535392ENST00000333334CLN3chr1628495327-C15orf32chr1593043588+0.202640560.79735947
ENST00000360019ENST00000333334CLN3chr1628495327-C15orf32chr1593043588+0.313042940.686957
ENST00000333496ENST00000333334CLN3chr1628495327-C15orf32chr1593043588+0.366736260.63326377
ENST00000355477ENST00000333334CLN3chr1628495327-C15orf32chr1593043588+0.205869350.7941307
ENST00000354630ENST00000333334CLN3chr1628495327-C15orf32chr1593043588+0.305061580.69493836
ENST00000567963ENST00000333334CLN3chr1628495327-C15orf32chr1593043588+0.3154880.68451196

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Fusion Genomic Features for CLN3-C15orf32


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CLN3chr1628495326-C15orf32chr1593043587+0.0012014780.9987985
CLN3chr1628495326-C15orf32chr1593043587+0.0012014780.9987985
CLN3chr1628495326-C15orf32chr1593043587+0.0012014780.9987985
CLN3chr1628495326-C15orf32chr1593043587+0.0012014780.9987985

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CLN3-C15orf32


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:28495327/chr15:93043588)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015149_151263422.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015173_182263422.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-10151_37263422.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-101559_127263422.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915149_151215391.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915173_182215391.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-9151_37215391.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-91559_127215391.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612149_151164340.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-6121_37164340.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-61259_127164340.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915149_151263439.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915173_182263439.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-9151_37263439.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-91559_127263439.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016149_151263439.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016173_182263439.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-10161_37263439.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-101659_127263439.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914149_151263422.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914173_182263422.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-9141_37263422.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-91459_127263422.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117149_151263439.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117173_182263439.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-11171_37263439.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-111759_127263439.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015128_148263422.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015152_172263422.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015183_203263422.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-101538_58263422.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915128_148215391.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915152_172215391.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915183_203215391.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-91538_58215391.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612128_148164340.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-61238_58164340.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915128_148263439.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915152_172263439.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915183_203263439.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-91538_58263439.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016128_148263439.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016152_172263439.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016183_203263439.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-101638_58263439.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914128_148263422.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914152_172263422.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914183_203263422.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-91438_58263422.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117128_148263439.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117152_172263439.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117183_203263439.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-111738_58263439.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015409_419263422.0MotifLysosomal targeting motif
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915409_419215391.0MotifLysosomal targeting motif
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112409_4190254.0MotifLysosomal targeting motif
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612409_419164340.0MotifLysosomal targeting motif
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915409_419263439.0MotifLysosomal targeting motif
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016409_419263439.0MotifLysosomal targeting motif
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914409_419263422.0MotifLysosomal targeting motif
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117409_419263439.0MotifLysosomal targeting motif
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015204_277263422.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015299_346263422.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015368_438263422.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915204_277215391.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915299_346215391.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915368_438215391.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112149_1510254.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112173_1820254.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-1121_370254.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112204_2770254.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112299_3460254.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112368_4380254.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-11259_1270254.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612173_182164340.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612204_277164340.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612299_346164340.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612368_438164340.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915204_277263439.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915299_346263439.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915368_438263439.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016204_277263439.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016299_346263439.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016368_438263439.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914204_277263422.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914299_346263422.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914368_438263422.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117204_277263439.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117299_346263439.0Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117368_438263439.0Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015278_298263422.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015347_367263422.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915278_298215391.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915347_367215391.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112128_1480254.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112152_1720254.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112183_2030254.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112278_2980254.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112347_3670254.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-11238_580254.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612152_172164340.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612183_203164340.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612278_298164340.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612347_367164340.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915278_298263439.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915347_367263439.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016278_298263439.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016347_367263439.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914278_298263422.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914347_367263422.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117278_298263439.0TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117347_367263439.0TransmembraneHelical


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Fusion Gene Sequence for CLN3-C15orf32


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>17230_17230_1_CLN3-C15orf32_CLN3_chr16_28495327_ENST00000333496_C15orf32_chr15_93043588_ENST00000333334_length(transcript)=1577nt_BP=817nt
AGAACATTCTGCTGCTCTTAAAGACCCTCATCCCTCCCGTGGGAGCCCCCTTTGGACACTCTATGACCCTGGACCCTCGGGGGACCTGAA
CTTGATGCGATGGGAGGCTGTGCAGGCTCGCGGCGGCGCTTTTCGGATTCCGAGGGGGAGGAGACCGTCCCGGAGCCCCGGCTCCCTCTG
TTGGACCATCAGGGCGCGCATTGGAAGAACGCGGTGGGCTTCTGGCTGCTGGGCCTTTGCAACAACTTCTCTTATGTGGTGATGCTGAGT
GCCGCCCACGACATCCTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATC
AAATTGTTGGCTCCTCTTGGCCTTCACCTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTG
GTTGCCTTTTCTCATTCTGTGGGGACCAGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCC
CTCACTGCCTTCTACCCCAGGGCCGTGATCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCCTACCTGGGC
CTCACCCAGGCCGGCCTCTCCCCTCAGCAGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTCTTGTTGCTC
ACATCTCCTGAGGCCCAGGACCCTGGAGGGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCG
AAGCCAGGGAACATTTAATAAGATACAGAAACCAGATTTGCTTGAGCTGAATGCTGGATCGCCATGGCAACCTTCCTTTGGAGGTTATCC
AAGTCAGGTAGTGACAGCAAAGCTGAGTTAAAGGTCACCCCTGCTGAGAAAGATGGGCATTGATAAAGGATTTTAACAAGACCCAGAGGA
GCTGGTATTTGGAAGCTACCTACAGAGGATCGACGAGGCCCTAGGAATGGGTGGCAAACAACATCAGGAAGAGGGGGGCATCCTGCAGGG
GCTCCCACCAGAGCCCCGACCTCGCCCTTCAGATCGGGAGCTCCAGCCTTCACCAGAAGCTGAGATTGGAGCTGTTCGTAATTGTTCAAT
GGAAGGGGGAACAACCATTTTAACCAGGCATCCAGATGGGAAAGAAATACACTTATGCCACTCTACACCCAAGACACGCATTCCTGAAAA
GTTCTGAACAAGCCAAATGCTTGCAAATGGAACGGGCTTGACCTTCTTTATCACTCCAGAAATGCTTTATTTAATCTTTTTTCTATTGGA
GCATCACTTTAAAACCTCAAAGTTGAGAAGGCTTTTCTTTGCATGATGCTGAAGCCAGAAGCCTTCAAGGAAACAACATAAATATAAATA
TCTCTGTGGCCAGTCTCTACAAAAATACATAAAAATGAATTTTAAGCATAATAAAATGTGAAAAATTGCCCAACTTTCCTCACAAATGAG

>17230_17230_1_CLN3-C15orf32_CLN3_chr16_28495327_ENST00000333496_C15orf32_chr15_93043588_ENST00000333334_length(amino acids)=242AA_BP=
MGGCAGSRRRFSDSEGEETVPEPRLPLLDHQGAHWKNAVGFWLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHAVLLADILPTLVIKLL
APLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVFASISSGLGEVTFLSLTAFYPRAVISWWSSGTGGAGLLGALSYLGLTQ

--------------------------------------------------------------
>17230_17230_2_CLN3-C15orf32_CLN3_chr16_28495327_ENST00000354630_C15orf32_chr15_93043588_ENST00000333334_length(transcript)=1667nt_BP=907nt
ACGGCCTCTGCATAGTGCAGAACATTCTGCTGCTCTTAAAGACCCTCATCCCTCCCGTGGGAGCCCCCTTTGGACACTCTATGACCCTGG
ACCCTCGGGGGACCTGAACTTGATGCGATGGGAGGCTGTGCAGGCTCGCGGCGGCGCTTTTCGGATTCCGAGGGGGAGGAGACCGTCCCG
GAGCCCCGGCTCCCTCTGTTGGACCATCAGGGCGCGCATTGGAAGAACGCGGTGGGCTTCTGGCTGCTGGGCCTTTGCAACAACTTCTCT
TATGTGGTGATGCTGAGTGCCGCCCACGACATCCTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGTGGACCCAGGCCCAACGCCG
ATCCCCCACAACAGCTCATCACGATTTGACTGCAACTCTGTCTCTACGGCTGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATC
AAATTGTTGGCTCCTCTTGGCCTTCACCTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTG
GTTGCCTTTTCTCATTCTGTGGGGACCAGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCC
CTCACTGCCTTCTACCCCAGGGCCGTGATCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCCTACCTGGGC
CTCACCCAGGCCGGCCTCTCCCCTCAGCAGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTCTTGTTGCTC
ACATCTCCTGAGGCCCAGGACCCTGGAGGGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCG
AAGCCAGGGAACATTTAATAAGATACAGAAACCAGATTTGCTTGAGCTGAATGCTGGATCGCCATGGCAACCTTCCTTTGGAGGTTATCC
AAGTCAGGTAGTGACAGCAAAGCTGAGTTAAAGGTCACCCCTGCTGAGAAAGATGGGCATTGATAAAGGATTTTAACAAGACCCAGAGGA
GCTGGTATTTGGAAGCTACCTACAGAGGATCGACGAGGCCCTAGGAATGGGTGGCAAACAACATCAGGAAGAGGGGGGCATCCTGCAGGG
GCTCCCACCAGAGCCCCGACCTCGCCCTTCAGATCGGGAGCTCCAGCCTTCACCAGAAGCTGAGATTGGAGCTGTTCGTAATTGTTCAAT
GGAAGGGGGAACAACCATTTTAACCAGGCATCCAGATGGGAAAGAAATACACTTATGCCACTCTACACCCAAGACACGCATTCCTGAAAA
GTTCTGAACAAGCCAAATGCTTGCAAATGGAACGGGCTTGACCTTCTTTATCACTCCAGAAATGCTTTATTTAATCTTTTTTCTATTGGA
GCATCACTTTAAAACCTCAAAGTTGAGAAGGCTTTTCTTTGCATGATGCTGAAGCCAGAAGCCTTCAAGGAAACAACATAAATATAAATA
TCTCTGTGGCCAGTCTCTACAAAAATACATAAAAATGAATTTTAAGCATAATAAAATGTGAAAAATTGCCCAACTTTCCTCACAAATGAG

>17230_17230_2_CLN3-C15orf32_CLN3_chr16_28495327_ENST00000354630_C15orf32_chr15_93043588_ENST00000333334_length(amino acids)=266AA_BP=
MGGCAGSRRRFSDSEGEETVPEPRLPLLDHQGAHWKNAVGFWLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHVDPGPTPIPHNSSSRF
DCNSVSTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVFASISSGLGEVTFLSLTAFYPRAV

--------------------------------------------------------------
>17230_17230_3_CLN3-C15orf32_CLN3_chr16_28495327_ENST00000355477_C15orf32_chr15_93043588_ENST00000333334_length(transcript)=1523nt_BP=763nt
ACGGCCTCTGCATAGTGCAGAACATTCTGCTGCTCTTAAAGACCCTCATCCCTCCCGTGGGAGCCCCCTTTGGACACTCTATGACCCTGG
ACCCTCGGGGGACCTGAACTTGATGCGATGGGAGGCTGTGCAGGCTCGCGGCGGCGCTTTTCGGATTCCGAGGGGGAGGAGACCGTCCCG
GAGCCCCGGCTCCCTCTGTTGGACCATCAGGGCGCGCATTGGAAGAACGCGGTGGGCTTCTGGCTGCTGGGCCTTTGCAACAACTTCTCT
TATGTGGTGATGCTGAGTGCCGCCCACGACATCCTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGTGGACCCAGGCCCAACGCCG
ATCCCCCACAACAGCTCATCACGATTTGACTGCAACTCTGTCTCTACGGCTGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATC
AAATTGTTGGCTCCTCTTGGCCTTCACCTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTG
GTTGCCTTTTCTCATTCTGTGGGGACCAGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCC
CTCACTGCCTTCTACCCCAGCTATTTCTTGTTGCTCACATCTCCTGAGGCCCAGGACCCTGGAGGGGAAGAAGAAGCAGAGAGCGCAGCC
CGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCGAAGCCAGGGAACATTTAATAAGATACAGAAACCAGATTTGCTTGAGCTGAATGC
TGGATCGCCATGGCAACCTTCCTTTGGAGGTTATCCAAGTCAGGTAGTGACAGCAAAGCTGAGTTAAAGGTCACCCCTGCTGAGAAAGAT
GGGCATTGATAAAGGATTTTAACAAGACCCAGAGGAGCTGGTATTTGGAAGCTACCTACAGAGGATCGACGAGGCCCTAGGAATGGGTGG
CAAACAACATCAGGAAGAGGGGGGCATCCTGCAGGGGCTCCCACCAGAGCCCCGACCTCGCCCTTCAGATCGGGAGCTCCAGCCTTCACC
AGAAGCTGAGATTGGAGCTGTTCGTAATTGTTCAATGGAAGGGGGAACAACCATTTTAACCAGGCATCCAGATGGGAAAGAAATACACTT
ATGCCACTCTACACCCAAGACACGCATTCCTGAAAAGTTCTGAACAAGCCAAATGCTTGCAAATGGAACGGGCTTGACCTTCTTTATCAC
TCCAGAAATGCTTTATTTAATCTTTTTTCTATTGGAGCATCACTTTAAAACCTCAAAGTTGAGAAGGCTTTTCTTTGCATGATGCTGAAG
CCAGAAGCCTTCAAGGAAACAACATAAATATAAATATCTCTGTGGCCAGTCTCTACAAAAATACATAAAAATGAATTTTAAGCATAATAA

>17230_17230_3_CLN3-C15orf32_CLN3_chr16_28495327_ENST00000355477_C15orf32_chr15_93043588_ENST00000333334_length(amino acids)=218AA_BP=
MGGCAGSRRRFSDSEGEETVPEPRLPLLDHQGAHWKNAVGFWLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHVDPGPTPIPHNSSSRF
DCNSVSTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVFASISSGLGEVTFLSLTAFYPSYF

--------------------------------------------------------------
>17230_17230_4_CLN3-C15orf32_CLN3_chr16_28495327_ENST00000360019_C15orf32_chr15_93043588_ENST00000333334_length(transcript)=1909nt_BP=1149nt
ATAACTGGTGCTGGCAGGCTACTGTCTCGGTCTTGGGCGCCACTGATCTAAGGTCACGGCTCTGCTTGCTGCTCCCACCCGCTCCAGTTT
AAAACCTGCGGTTCCAGGGTTCTCCAGCCCCTCCCTTTTTCACGCTCCGAAGCCGAGAAGGCCCAAAGCGAAGACAGAGAGGACCCGGAA
GTAGGGAAAACCTCTGAGCACGTGATGGGGGAACACGCGGGTGCTGTCACGTGATCCGACAAACGGCCTCTGCATAGTGCAGAACATTCT
GCTGCTCTTAAAGACCCTCATCCCTCCCGTGGGAGCCCCCTTTGGACACTCTATGACCCTGGACCCTCGGGGGACCTGAACTTGATGCGA
TGGGAGGCTGTGCAGGCTCGCGGCGGCGCTTTTCGGATTCCGAGGGGGAGGAGACCGTCCCGGAGCCCCGGCTCCCTCTGTTGGACCATC
AGGGCGCGCATTGGAAGAACGCGGTGGGCTTCTGGCTGCTGGGCCTTTGCAACAACTTCTCTTATGTGGTGATGCTGAGTGCCGCCCACG
ACATCCTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGTGGACCCAGGCCCAACGCCGATCCCCCACAACAGCTCATCACGATTTG
ACTGCAACTCTGTCTCTACGGCTGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATCAAATTGTTGGCTCCTCTTGGCCTTCACC
TGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTGGTTGCCTTTTCTCATTCTGTGGGGACCA
GCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCCCTCACTGCCTTCTACCCCAGGGCCGTGA
TCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCCTACCTGGGCCTCACCCAGGCCGGCCTCTCCCCTCAGC
AGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTCTTGTTGCTCACATCTCCTGAGGCCCAGGACCCTGGAG
GGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCGAAGCCAGGGAACATTTAATAAGATACAG
AAACCAGATTTGCTTGAGCTGAATGCTGGATCGCCATGGCAACCTTCCTTTGGAGGTTATCCAAGTCAGGTAGTGACAGCAAAGCTGAGT
TAAAGGTCACCCCTGCTGAGAAAGATGGGCATTGATAAAGGATTTTAACAAGACCCAGAGGAGCTGGTATTTGGAAGCTACCTACAGAGG
ATCGACGAGGCCCTAGGAATGGGTGGCAAACAACATCAGGAAGAGGGGGGCATCCTGCAGGGGCTCCCACCAGAGCCCCGACCTCGCCCT
TCAGATCGGGAGCTCCAGCCTTCACCAGAAGCTGAGATTGGAGCTGTTCGTAATTGTTCAATGGAAGGGGGAACAACCATTTTAACCAGG
CATCCAGATGGGAAAGAAATACACTTATGCCACTCTACACCCAAGACACGCATTCCTGAAAAGTTCTGAACAAGCCAAATGCTTGCAAAT
GGAACGGGCTTGACCTTCTTTATCACTCCAGAAATGCTTTATTTAATCTTTTTTCTATTGGAGCATCACTTTAAAACCTCAAAGTTGAGA
AGGCTTTTCTTTGCATGATGCTGAAGCCAGAAGCCTTCAAGGAAACAACATAAATATAAATATCTCTGTGGCCAGTCTCTACAAAAATAC
ATAAAAATGAATTTTAAGCATAATAAAATGTGAAAAATTGCCCAACTTTCCTCACAAATGAGTAAAAGCCAATTTAAATGATAAGAAATG

>17230_17230_4_CLN3-C15orf32_CLN3_chr16_28495327_ENST00000360019_C15orf32_chr15_93043588_ENST00000333334_length(amino acids)=266AA_BP=
MGGCAGSRRRFSDSEGEETVPEPRLPLLDHQGAHWKNAVGFWLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHVDPGPTPIPHNSSSRF
DCNSVSTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVFASISSGLGEVTFLSLTAFYPRAV

--------------------------------------------------------------
>17230_17230_5_CLN3-C15orf32_CLN3_chr16_28495327_ENST00000535392_C15orf32_chr15_93043588_ENST00000333334_length(transcript)=1652nt_BP=892nt
CCTCAGGGTCCCTGCTGTAGACGGGGCGGGGGAGAGTACGATGGGTGGGGCGTGGTGGGTCGTAGGGCGCTCGAGATGGAGCCCCCAGCT
TCCTTGATGGATCGCGGGGCGCGAGTGCCCTAGACAAGCCGGAGCTGGGACCGGCAATCGGGCGTTGATCCTTGTCACCTGTCGCAGACC
CTCATCCCTCCCGTGGGAGCCCCCTTTGGACACTCTATGACCCTGGACCCTCGGGGGACCTGAACTTGATGCGATGGGAGGCTGTGCAGG
CTCGCGGCGGCGCTTTTCGGATTCCGAGGGCTGCTGGGCCTTTGCAACAACTTCTCTTATGTGGTGATGCTGAGTGCCGCCCACGACATC
CTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATCAAATTGTTGGCTCCT
CTTGGCCTTCACCTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTGGTTGCCTTTTCTCAT
TCTGTGGGGACCAGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCCCTCACTGCCTTCTAC
CCCAGGGCCGTGATCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCCTACCTGGGCCTCACCCAGGCCGGC
CTCTCCCCTCAGCAGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTCTTGTTGCTCACATCTCCTGAGGCC
CAGGACCCTGGAGGGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCGAAGCCAGGGAACATT
TAATAAGATACAGAAACCAGATTTGCTTGAGCTGAATGCTGGATCGCCATGGCAACCTTCCTTTGGAGGTTATCCAAGTCAGGTAGTGAC
AGCAAAGCTGAGTTAAAGGTCACCCCTGCTGAGAAAGATGGGCATTGATAAAGGATTTTAACAAGACCCAGAGGAGCTGGTATTTGGAAG
CTACCTACAGAGGATCGACGAGGCCCTAGGAATGGGTGGCAAACAACATCAGGAAGAGGGGGGCATCCTGCAGGGGCTCCCACCAGAGCC
CCGACCTCGCCCTTCAGATCGGGAGCTCCAGCCTTCACCAGAAGCTGAGATTGGAGCTGTTCGTAATTGTTCAATGGAAGGGGGAACAAC
CATTTTAACCAGGCATCCAGATGGGAAAGAAATACACTTATGCCACTCTACACCCAAGACACGCATTCCTGAAAAGTTCTGAACAAGCCA
AATGCTTGCAAATGGAACGGGCTTGACCTTCTTTATCACTCCAGAAATGCTTTATTTAATCTTTTTTCTATTGGAGCATCACTTTAAAAC
CTCAAAGTTGAGAAGGCTTTTCTTTGCATGATGCTGAAGCCAGAAGCCTTCAAGGAAACAACATAAATATAAATATCTCTGTGGCCAGTC
TCTACAAAAATACATAAAAATGAATTTTAAGCATAATAAAATGTGAAAAATTGCCCAACTTTCCTCACAAATGAGTAAAAGCCAATTTAA

>17230_17230_5_CLN3-C15orf32_CLN3_chr16_28495327_ENST00000535392_C15orf32_chr15_93043588_ENST00000333334_length(amino acids)=213AA_BP=
MCRLAAALFGFRGLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVA
FSHSVGTSLCGVVFASISSGLGEVTFLSLTAFYPRAVISWWSSGTGGAGLLGALSYLGLTQAGLSPQQTLLSMLGIPALLLASYFLLLTS

--------------------------------------------------------------
>17230_17230_6_CLN3-C15orf32_CLN3_chr16_28495327_ENST00000567963_C15orf32_chr15_93043588_ENST00000333334_length(transcript)=1662nt_BP=902nt
CTCTGCATAGTGCAGAACATTCTGCTGCTCTTAAAGACCCTCATCCCTCCCGTGGGAGCCCCCTTTGGACACTCTATGACCCTGGACCCT
CGGGGGACCTGAACTTGATGCGATGGGAGGCTGTGCAGGCTCGCGGCGGCGCTTTTCGGATTCCGAGGGGGAGGAGACCGTCCCGGAGCC
CCGGCTCCCTCTGTTGGACCATCAGGGCGCGCATTGGAAGAACGCGGTGGGCTTCTGGCTGCTGGGCCTTTGCAACAACTTCTCTTATGT
GGTGATGCTGAGTGCCGCCCACGACATCCTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGTGGACCCAGGCCCAACGCCGATCCC
CCACAACAGCTCATCACGATTTGACTGCAACTCTGTCTCTACGGCTGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATCAAATT
GTTGGCTCCTCTTGGCCTTCACCTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTGGTTGC
CTTTTCTCATTCTGTGGGGACCAGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCCCTCAC
TGCCTTCTACCCCAGGGCCGTGATCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCCTACCTGGGCCTCAC
CCAGGCCGGCCTCTCCCCTCAGCAGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTCTTGTTGCTCACATC
TCCTGAGGCCCAGGACCCTGGAGGGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCGAAGCC
AGGGAACATTTAATAAGATACAGAAACCAGATTTGCTTGAGCTGAATGCTGGATCGCCATGGCAACCTTCCTTTGGAGGTTATCCAAGTC
AGGTAGTGACAGCAAAGCTGAGTTAAAGGTCACCCCTGCTGAGAAAGATGGGCATTGATAAAGGATTTTAACAAGACCCAGAGGAGCTGG
TATTTGGAAGCTACCTACAGAGGATCGACGAGGCCCTAGGAATGGGTGGCAAACAACATCAGGAAGAGGGGGGCATCCTGCAGGGGCTCC
CACCAGAGCCCCGACCTCGCCCTTCAGATCGGGAGCTCCAGCCTTCACCAGAAGCTGAGATTGGAGCTGTTCGTAATTGTTCAATGGAAG
GGGGAACAACCATTTTAACCAGGCATCCAGATGGGAAAGAAATACACTTATGCCACTCTACACCCAAGACACGCATTCCTGAAAAGTTCT
GAACAAGCCAAATGCTTGCAAATGGAACGGGCTTGACCTTCTTTATCACTCCAGAAATGCTTTATTTAATCTTTTTTCTATTGGAGCATC
ACTTTAAAACCTCAAAGTTGAGAAGGCTTTTCTTTGCATGATGCTGAAGCCAGAAGCCTTCAAGGAAACAACATAAATATAAATATCTCT
GTGGCCAGTCTCTACAAAAATACATAAAAATGAATTTTAAGCATAATAAAATGTGAAAAATTGCCCAACTTTCCTCACAAATGAGTAAAA

>17230_17230_6_CLN3-C15orf32_CLN3_chr16_28495327_ENST00000567963_C15orf32_chr15_93043588_ENST00000333334_length(amino acids)=266AA_BP=
MGGCAGSRRRFSDSEGEETVPEPRLPLLDHQGAHWKNAVGFWLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHVDPGPTPIPHNSSSRF
DCNSVSTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVFASISSGLGEVTFLSLTAFYPRAV

--------------------------------------------------------------
>17230_17230_7_CLN3-C15orf32_CLN3_chr16_28495327_ENST00000568224_C15orf32_chr15_93043588_ENST00000333334_length(transcript)=1652nt_BP=892nt
CCTCAGGGTCCCTGCTGTAGACGGGGCGGGGGAGAGTACGATGGGTGGGGCGTGGTGGGTCGTAGGGCGCTCGAGATGGAGCCCCCAGCT
TCCTTGATGGATCGCGGGGCGCGAGTGCCCTAGACAAGCCGGAGCTGGGACCGGCAATCGGGCGTTGATCCTTGTCACCTGTCGCAGACC
CTCATCCCTCCCGTGGGAGCCCCCTTTGGACACTCTATGACCCTGGACCCTCGGGGGACCTGAACTTGATGCGATGGGAGGCTGTGCAGG
CTCGCGGCGGCGCTTTTCGGATTCCGAGGGCTGCTGGGCCTTTGCAACAACTTCTCTTATGTGGTGATGCTGAGTGCCGCCCACGACATC
CTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATCAAATTGTTGGCTCCT
CTTGGCCTTCACCTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTGGTTGCCTTTTCTCAT
TCTGTGGGGACCAGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCCCTCACTGCCTTCTAC
CCCAGGGCCGTGATCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCCTACCTGGGCCTCACCCAGGCCGGC
CTCTCCCCTCAGCAGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTCTTGTTGCTCACATCTCCTGAGGCC
CAGGACCCTGGAGGGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCGAAGCCAGGGAACATT
TAATAAGATACAGAAACCAGATTTGCTTGAGCTGAATGCTGGATCGCCATGGCAACCTTCCTTTGGAGGTTATCCAAGTCAGGTAGTGAC
AGCAAAGCTGAGTTAAAGGTCACCCCTGCTGAGAAAGATGGGCATTGATAAAGGATTTTAACAAGACCCAGAGGAGCTGGTATTTGGAAG
CTACCTACAGAGGATCGACGAGGCCCTAGGAATGGGTGGCAAACAACATCAGGAAGAGGGGGGCATCCTGCAGGGGCTCCCACCAGAGCC
CCGACCTCGCCCTTCAGATCGGGAGCTCCAGCCTTCACCAGAAGCTGAGATTGGAGCTGTTCGTAATTGTTCAATGGAAGGGGGAACAAC
CATTTTAACCAGGCATCCAGATGGGAAAGAAATACACTTATGCCACTCTACACCCAAGACACGCATTCCTGAAAAGTTCTGAACAAGCCA
AATGCTTGCAAATGGAACGGGCTTGACCTTCTTTATCACTCCAGAAATGCTTTATTTAATCTTTTTTCTATTGGAGCATCACTTTAAAAC
CTCAAAGTTGAGAAGGCTTTTCTTTGCATGATGCTGAAGCCAGAAGCCTTCAAGGAAACAACATAAATATAAATATCTCTGTGGCCAGTC
TCTACAAAAATACATAAAAATGAATTTTAAGCATAATAAAATGTGAAAAATTGCCCAACTTTCCTCACAAATGAGTAAAAGCCAATTTAA

>17230_17230_7_CLN3-C15orf32_CLN3_chr16_28495327_ENST00000568224_C15orf32_chr15_93043588_ENST00000333334_length(amino acids)=213AA_BP=
MCRLAAALFGFRGLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVA
FSHSVGTSLCGVVFASISSGLGEVTFLSLTAFYPRAVISWWSSGTGGAGLLGALSYLGLTQAGLSPQQTLLSMLGIPALLLASYFLLLTS

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Fusion Gene PPI Analysis for CLN3-C15orf32


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CLN3-C15orf32


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CLN3-C15orf32


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCLN3C0751383Juvenile Neuronal Ceroid Lipofuscinosis7CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneCLN3C0024623Malignant neoplasm of stomach1CTD_human
HgeneCLN3C0038356Stomach Neoplasms1CTD_human
HgeneCLN3C0235874Disease Exacerbation1CTD_human
HgeneCLN3C1708349Hereditary Diffuse Gastric Cancer1CTD_human