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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:CSPG4-SON (FusionGDB2 ID:HG1464TG6651)

Fusion Gene Summary for CSPG4-SON

check button Fusion gene summary
Fusion gene informationFusion gene name: CSPG4-SON
Fusion gene ID: hg1464tg6651
HgeneTgene
Gene symbol

CSPG4

SON

Gene ID

1464

6651

Gene namechondroitin sulfate proteoglycan 4SON DNA and RNA binding protein
SynonymsHMW-MAA|MCSP|MCSPG|MEL-CSPG|MSK16|NG2BASS1|C21orf50|DBP-5|NREBP|SON3|TOKIMS
Cytomap('CSPG4')('SON')

15q24.2

21q22.11

Type of geneprotein-codingprotein-coding
Descriptionchondroitin sulfate proteoglycan 4chondroitin sulfate proteoglycan 4 (melanoma-associated)chondroitin sulfate proteoglycan NG2melanoma chondroitin sulfate proteoglycanmelanoma-associated chondroitin sulfate proteoglycanprotein SONBax antagonist selected in Saccharomyces 1NRE-binding proteinSON DNA binding proteinnegative regulatory element-binding protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000308508, 
Fusion gene scores* DoF score5 X 4 X 3=6016 X 15 X 5=1200
# samples 516
** MAII scorelog2(5/60*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(16/1200*10)=-2.90689059560852
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CSPG4 [Title/Abstract] AND SON [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCSPG4(75977076)-SON(34945612), # samples:1
Anticipated loss of major functional domain due to fusion event.CSPG4-SON seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CSPG4-SON seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CSPG4-SON seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CSPG4-SON seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCSPG4

GO:0035556

intracellular signal transduction

10587647

HgeneCSPG4

GO:0050731

positive regulation of peptidyl-tyrosine phosphorylation

10587647

TgeneSON

GO:0006397

mRNA processing

21504830

TgeneSON

GO:0043066

negative regulation of apoptotic process

10509013

TgeneSON

GO:0048024

regulation of mRNA splicing, via spliceosome

21504830


check buttonFusion gene breakpoints across CSPG4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across SON (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand


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Fusion Gene ORF analysis for CSPG4-SON

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000308508ENST00000356577CSPG4chr1575977076-SONchr2134945612+0.001260610.9987394
ENST00000308508ENST00000290239CSPG4chr1575977076-SONchr2134945612+0.0012145380.99878544
ENST00000308508ENST00000381692CSPG4chr1575977076-SONchr2134945612+0.001260610.9987394

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Fusion Genomic Features for CSPG4-SON


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CSPG4chr1575977076-SONchr2134945613+0.0119872350.9880128
CSPG4chr1575977076-SONchr2134945613+0.0119872350.9880128

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CSPG4-SON


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:75977076/chr21:34945612)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-510202_38014832323.0DomainLaminin G-like 2
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-51030_19214832323.0DomainLaminin G-like 1
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-51030_63914832323.0RegionNeurite growth inhibition
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-5101018_111014832323.0RepeatCSPG 6
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-5101126_121614832323.0RepeatCSPG 7
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-5101238_133714832323.0RepeatCSPG 8
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-5101356_144914832323.0RepeatCSPG 9
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-510428_52314832323.0RepeatCSPG 1
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-510553_64514832323.0RepeatCSPG 2
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-510662_76414832323.0RepeatCSPG 3
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-510783_87814832323.0RepeatCSPG 4
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-510898_98914832323.0RepeatCSPG 5
TgeneSONchr15:75977076chr21:34945612ENST000002902398132371_24262321699.6666666666666DomainDRBM
TgeneSONchr15:75977076chr21:34945612ENST00000300278072305_235102304.0DomainG-patch
TgeneSONchr15:75977076chr21:34945612ENST00000300278072371_242602304.0DomainDRBM
TgeneSONchr15:75977076chr21:34945612ENST000003565777122305_235122952427.0DomainG-patch
TgeneSONchr15:75977076chr21:34945612ENST000003565777122371_242622952427.0DomainDRBM
TgeneSONchr15:75977076chr21:34945612ENST00000381679052305_235102109.0DomainG-patch
TgeneSONchr15:75977076chr21:34945612ENST00000381679052371_242602109.0DomainDRBM
TgeneSONchr15:75977076chr21:34945612ENST00000300278071006_112602304.0RegionNote=14 X 6 AA repeats of [ED]-R-S-M-M-S
TgeneSONchr15:75977076chr21:34945612ENST00000300278071147_117902304.0RegionNote=3 X 11 AA tandem repats of P-P-L-P-P-E-E-P-P-[TME]-[MTG]
TgeneSONchr15:75977076chr21:34945612ENST00000300278071359_139002304.0RegionNote=4 X 8 AA tandem repeats of V-L-E-SS-[AVT]-VT
TgeneSONchr15:75977076chr21:34945612ENST00000300278071925_199402304.0RegionNote=7 X 7 AA repeats of P-S-R-R-S-R-[TS]
TgeneSONchr15:75977076chr21:34945612ENST00000300278071934_201302304.0RegionNote=2 X 19 AA repeats of P-S-R-R-R-R-S-R-S-V-V-R-R-R-S-F-S-I-S
TgeneSONchr15:75977076chr21:34945612ENST00000300278072013_203902304.0RegionNote=3 X tandem repeats of [ST]-P-[VLI]-R-[RL]-[RK]-[RF]-S-R
TgeneSONchr15:75977076chr21:34945612ENST0000030027807726_89502304.0RegionNote=17 X 10 AA tandem repeats of L-A-[ST]-[NSG]-[TS]-MDSQM
TgeneSONchr15:75977076chr21:34945612ENST0000030027807912_98802304.0RegionNote=11 X 7 AA tandem repeats of [DR]-P-Y-R-[LI][AG][QHP]
TgeneSONchr15:75977076chr21:34945612ENST00000381679051006_112602109.0RegionNote=14 X 6 AA repeats of [ED]-R-S-M-M-S
TgeneSONchr15:75977076chr21:34945612ENST00000381679051147_117902109.0RegionNote=3 X 11 AA tandem repats of P-P-L-P-P-E-E-P-P-[TME]-[MTG]
TgeneSONchr15:75977076chr21:34945612ENST00000381679051359_139002109.0RegionNote=4 X 8 AA tandem repeats of V-L-E-SS-[AVT]-VT
TgeneSONchr15:75977076chr21:34945612ENST00000381679051925_199402109.0RegionNote=7 X 7 AA repeats of P-S-R-R-S-R-[TS]
TgeneSONchr15:75977076chr21:34945612ENST00000381679051934_201302109.0RegionNote=2 X 19 AA repeats of P-S-R-R-R-R-S-R-S-V-V-R-R-R-S-F-S-I-S
TgeneSONchr15:75977076chr21:34945612ENST00000381679052013_203902109.0RegionNote=3 X tandem repeats of [ST]-P-[VLI]-R-[RL]-[RK]-[RF]-S-R
TgeneSONchr15:75977076chr21:34945612ENST0000038167905726_89502109.0RegionNote=17 X 10 AA tandem repeats of L-A-[ST]-[NSG]-[TS]-MDSQM
TgeneSONchr15:75977076chr21:34945612ENST0000038167905912_98802109.0RegionNote=11 X 7 AA tandem repeats of [DR]-P-Y-R-[LI][AG][QHP]
TgeneSONchr15:75977076chr21:34945612ENST00000300278071006_101102304.0RepeatNote=1-1
TgeneSONchr15:75977076chr21:34945612ENST00000300278071014_101902304.0RepeatNote=1-2
TgeneSONchr15:75977076chr21:34945612ENST00000300278071021_102602304.0RepeatNote=1-3
TgeneSONchr15:75977076chr21:34945612ENST00000300278071030_103502304.0RepeatNote=1-4
TgeneSONchr15:75977076chr21:34945612ENST00000300278071038_104302304.0RepeatNote=1-5
TgeneSONchr15:75977076chr21:34945612ENST00000300278071046_105102304.0RepeatNote=1-6
TgeneSONchr15:75977076chr21:34945612ENST00000300278071055_106002304.0RepeatNote=1-7
TgeneSONchr15:75977076chr21:34945612ENST00000300278071063_106802304.0RepeatNote=1-8
TgeneSONchr15:75977076chr21:34945612ENST00000300278071071_107602304.0RepeatNote=1-9
TgeneSONchr15:75977076chr21:34945612ENST00000300278071080_108502304.0RepeatNote=1-10
TgeneSONchr15:75977076chr21:34945612ENST00000300278071089_109402304.0RepeatNote=1-11
TgeneSONchr15:75977076chr21:34945612ENST00000300278071100_110502304.0RepeatNote=1-12
TgeneSONchr15:75977076chr21:34945612ENST00000300278071111_111602304.0RepeatNote=1-13
TgeneSONchr15:75977076chr21:34945612ENST00000300278071121_112602304.0RepeatNote=1-14
TgeneSONchr15:75977076chr21:34945612ENST00000300278071925_193102304.0RepeatNote=2-1
TgeneSONchr15:75977076chr21:34945612ENST00000300278071934_195202304.0RepeatNote=3-1
TgeneSONchr15:75977076chr21:34945612ENST00000300278071953_195902304.0RepeatNote=2-2
TgeneSONchr15:75977076chr21:34945612ENST00000300278071960_196602304.0RepeatNote=2-3
TgeneSONchr15:75977076chr21:34945612ENST00000300278071967_197302304.0RepeatNote=2-4
TgeneSONchr15:75977076chr21:34945612ENST00000300278071974_198002304.0RepeatNote=2-5
TgeneSONchr15:75977076chr21:34945612ENST00000300278071981_198702304.0RepeatNote=2-6
TgeneSONchr15:75977076chr21:34945612ENST00000300278071988_199402304.0RepeatNote=2-7
TgeneSONchr15:75977076chr21:34945612ENST00000300278071995_201302304.0RepeatNote=3-2
TgeneSONchr15:75977076chr21:34945612ENST00000381679051006_101102109.0RepeatNote=1-1
TgeneSONchr15:75977076chr21:34945612ENST00000381679051014_101902109.0RepeatNote=1-2
TgeneSONchr15:75977076chr21:34945612ENST00000381679051021_102602109.0RepeatNote=1-3
TgeneSONchr15:75977076chr21:34945612ENST00000381679051030_103502109.0RepeatNote=1-4
TgeneSONchr15:75977076chr21:34945612ENST00000381679051038_104302109.0RepeatNote=1-5
TgeneSONchr15:75977076chr21:34945612ENST00000381679051046_105102109.0RepeatNote=1-6
TgeneSONchr15:75977076chr21:34945612ENST00000381679051055_106002109.0RepeatNote=1-7
TgeneSONchr15:75977076chr21:34945612ENST00000381679051063_106802109.0RepeatNote=1-8
TgeneSONchr15:75977076chr21:34945612ENST00000381679051071_107602109.0RepeatNote=1-9
TgeneSONchr15:75977076chr21:34945612ENST00000381679051080_108502109.0RepeatNote=1-10
TgeneSONchr15:75977076chr21:34945612ENST00000381679051089_109402109.0RepeatNote=1-11
TgeneSONchr15:75977076chr21:34945612ENST00000381679051100_110502109.0RepeatNote=1-12
TgeneSONchr15:75977076chr21:34945612ENST00000381679051111_111602109.0RepeatNote=1-13
TgeneSONchr15:75977076chr21:34945612ENST00000381679051121_112602109.0RepeatNote=1-14
TgeneSONchr15:75977076chr21:34945612ENST00000381679051925_193102109.0RepeatNote=2-1
TgeneSONchr15:75977076chr21:34945612ENST00000381679051934_195202109.0RepeatNote=3-1
TgeneSONchr15:75977076chr21:34945612ENST00000381679051953_195902109.0RepeatNote=2-2
TgeneSONchr15:75977076chr21:34945612ENST00000381679051960_196602109.0RepeatNote=2-3
TgeneSONchr15:75977076chr21:34945612ENST00000381679051967_197302109.0RepeatNote=2-4
TgeneSONchr15:75977076chr21:34945612ENST00000381679051974_198002109.0RepeatNote=2-5
TgeneSONchr15:75977076chr21:34945612ENST00000381679051981_198702109.0RepeatNote=2-6
TgeneSONchr15:75977076chr21:34945612ENST00000381679051988_199402109.0RepeatNote=2-7
TgeneSONchr15:75977076chr21:34945612ENST00000381679051995_201302109.0RepeatNote=3-2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-510639_158614832323.0Compositional biasNote=Gly/Ser-rich (glycosaminoglycan attachment domain)
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-5102320_232214832323.0MotifNote=PDZ-binding
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-5101586_222114832323.0RegionNeurite growth inhibition
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-5101587_222114832323.0RegionNote=Cysteine-containing
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-5101473_156314832323.0RepeatCSPG 10
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-5101581_167914832323.0RepeatCSPG 11
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-5101704_180314832323.0RepeatCSPG 12
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-5101832_192414832323.0RepeatCSPG 13
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-5101941_202914832323.0RepeatCSPG 14
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-5102038_214714832323.0RepeatCSPG 15
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-5102246_232214832323.0Topological domainCytoplasmic
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-51030_222414832323.0Topological domainExtracellular
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-5102225_224514832323.0TransmembraneHelical
TgeneSONchr15:75977076chr21:34945612ENST000002902398132305_23512321699.6666666666666DomainG-patch
TgeneSONchr15:75977076chr21:34945612ENST000002902398131006_11262321699.6666666666666RegionNote=14 X 6 AA repeats of [ED]-R-S-M-M-S
TgeneSONchr15:75977076chr21:34945612ENST000002902398131147_11792321699.6666666666666RegionNote=3 X 11 AA tandem repats of P-P-L-P-P-E-E-P-P-[TME]-[MTG]
TgeneSONchr15:75977076chr21:34945612ENST000002902398131359_13902321699.6666666666666RegionNote=4 X 8 AA tandem repeats of V-L-E-SS-[AVT]-VT
TgeneSONchr15:75977076chr21:34945612ENST000002902398131925_19942321699.6666666666666RegionNote=7 X 7 AA repeats of P-S-R-R-S-R-[TS]
TgeneSONchr15:75977076chr21:34945612ENST000002902398131934_20132321699.6666666666666RegionNote=2 X 19 AA repeats of P-S-R-R-R-R-S-R-S-V-V-R-R-R-S-F-S-I-S
TgeneSONchr15:75977076chr21:34945612ENST000002902398132013_20392321699.6666666666666RegionNote=3 X tandem repeats of [ST]-P-[VLI]-R-[RL]-[RK]-[RF]-S-R
TgeneSONchr15:75977076chr21:34945612ENST00000290239813726_8952321699.6666666666666RegionNote=17 X 10 AA tandem repeats of L-A-[ST]-[NSG]-[TS]-MDSQM
TgeneSONchr15:75977076chr21:34945612ENST00000290239813912_9882321699.6666666666666RegionNote=11 X 7 AA tandem repeats of [DR]-P-Y-R-[LI][AG][QHP]
TgeneSONchr15:75977076chr21:34945612ENST000003565777121006_112622952427.0RegionNote=14 X 6 AA repeats of [ED]-R-S-M-M-S
TgeneSONchr15:75977076chr21:34945612ENST000003565777121147_117922952427.0RegionNote=3 X 11 AA tandem repats of P-P-L-P-P-E-E-P-P-[TME]-[MTG]
TgeneSONchr15:75977076chr21:34945612ENST000003565777121359_139022952427.0RegionNote=4 X 8 AA tandem repeats of V-L-E-SS-[AVT]-VT
TgeneSONchr15:75977076chr21:34945612ENST000003565777121925_199422952427.0RegionNote=7 X 7 AA repeats of P-S-R-R-S-R-[TS]
TgeneSONchr15:75977076chr21:34945612ENST000003565777121934_201322952427.0RegionNote=2 X 19 AA repeats of P-S-R-R-R-R-S-R-S-V-V-R-R-R-S-F-S-I-S
TgeneSONchr15:75977076chr21:34945612ENST000003565777122013_203922952427.0RegionNote=3 X tandem repeats of [ST]-P-[VLI]-R-[RL]-[RK]-[RF]-S-R
TgeneSONchr15:75977076chr21:34945612ENST00000356577712726_89522952427.0RegionNote=17 X 10 AA tandem repeats of L-A-[ST]-[NSG]-[TS]-MDSQM
TgeneSONchr15:75977076chr21:34945612ENST00000356577712912_98822952427.0RegionNote=11 X 7 AA tandem repeats of [DR]-P-Y-R-[LI][AG][QHP]
TgeneSONchr15:75977076chr21:34945612ENST000002902398131006_10112321699.6666666666666RepeatNote=1-1
TgeneSONchr15:75977076chr21:34945612ENST000002902398131014_10192321699.6666666666666RepeatNote=1-2
TgeneSONchr15:75977076chr21:34945612ENST000002902398131021_10262321699.6666666666666RepeatNote=1-3
TgeneSONchr15:75977076chr21:34945612ENST000002902398131030_10352321699.6666666666666RepeatNote=1-4
TgeneSONchr15:75977076chr21:34945612ENST000002902398131038_10432321699.6666666666666RepeatNote=1-5
TgeneSONchr15:75977076chr21:34945612ENST000002902398131046_10512321699.6666666666666RepeatNote=1-6
TgeneSONchr15:75977076chr21:34945612ENST000002902398131055_10602321699.6666666666666RepeatNote=1-7
TgeneSONchr15:75977076chr21:34945612ENST000002902398131063_10682321699.6666666666666RepeatNote=1-8
TgeneSONchr15:75977076chr21:34945612ENST000002902398131071_10762321699.6666666666666RepeatNote=1-9
TgeneSONchr15:75977076chr21:34945612ENST000002902398131080_10852321699.6666666666666RepeatNote=1-10
TgeneSONchr15:75977076chr21:34945612ENST000002902398131089_10942321699.6666666666666RepeatNote=1-11
TgeneSONchr15:75977076chr21:34945612ENST000002902398131100_11052321699.6666666666666RepeatNote=1-12
TgeneSONchr15:75977076chr21:34945612ENST000002902398131111_11162321699.6666666666666RepeatNote=1-13
TgeneSONchr15:75977076chr21:34945612ENST000002902398131121_11262321699.6666666666666RepeatNote=1-14
TgeneSONchr15:75977076chr21:34945612ENST000002902398131925_19312321699.6666666666666RepeatNote=2-1
TgeneSONchr15:75977076chr21:34945612ENST000002902398131934_19522321699.6666666666666RepeatNote=3-1
TgeneSONchr15:75977076chr21:34945612ENST000002902398131953_19592321699.6666666666666RepeatNote=2-2
TgeneSONchr15:75977076chr21:34945612ENST000002902398131960_19662321699.6666666666666RepeatNote=2-3
TgeneSONchr15:75977076chr21:34945612ENST000002902398131967_19732321699.6666666666666RepeatNote=2-4
TgeneSONchr15:75977076chr21:34945612ENST000002902398131974_19802321699.6666666666666RepeatNote=2-5
TgeneSONchr15:75977076chr21:34945612ENST000002902398131981_19872321699.6666666666666RepeatNote=2-6
TgeneSONchr15:75977076chr21:34945612ENST000002902398131988_19942321699.6666666666666RepeatNote=2-7
TgeneSONchr15:75977076chr21:34945612ENST000002902398131995_20132321699.6666666666666RepeatNote=3-2
TgeneSONchr15:75977076chr21:34945612ENST000003565777121006_101122952427.0RepeatNote=1-1
TgeneSONchr15:75977076chr21:34945612ENST000003565777121014_101922952427.0RepeatNote=1-2
TgeneSONchr15:75977076chr21:34945612ENST000003565777121021_102622952427.0RepeatNote=1-3
TgeneSONchr15:75977076chr21:34945612ENST000003565777121030_103522952427.0RepeatNote=1-4
TgeneSONchr15:75977076chr21:34945612ENST000003565777121038_104322952427.0RepeatNote=1-5
TgeneSONchr15:75977076chr21:34945612ENST000003565777121046_105122952427.0RepeatNote=1-6
TgeneSONchr15:75977076chr21:34945612ENST000003565777121055_106022952427.0RepeatNote=1-7
TgeneSONchr15:75977076chr21:34945612ENST000003565777121063_106822952427.0RepeatNote=1-8
TgeneSONchr15:75977076chr21:34945612ENST000003565777121071_107622952427.0RepeatNote=1-9
TgeneSONchr15:75977076chr21:34945612ENST000003565777121080_108522952427.0RepeatNote=1-10
TgeneSONchr15:75977076chr21:34945612ENST000003565777121089_109422952427.0RepeatNote=1-11
TgeneSONchr15:75977076chr21:34945612ENST000003565777121100_110522952427.0RepeatNote=1-12
TgeneSONchr15:75977076chr21:34945612ENST000003565777121111_111622952427.0RepeatNote=1-13
TgeneSONchr15:75977076chr21:34945612ENST000003565777121121_112622952427.0RepeatNote=1-14
TgeneSONchr15:75977076chr21:34945612ENST000003565777121925_193122952427.0RepeatNote=2-1
TgeneSONchr15:75977076chr21:34945612ENST000003565777121934_195222952427.0RepeatNote=3-1
TgeneSONchr15:75977076chr21:34945612ENST000003565777121953_195922952427.0RepeatNote=2-2
TgeneSONchr15:75977076chr21:34945612ENST000003565777121960_196622952427.0RepeatNote=2-3
TgeneSONchr15:75977076chr21:34945612ENST000003565777121967_197322952427.0RepeatNote=2-4
TgeneSONchr15:75977076chr21:34945612ENST000003565777121974_198022952427.0RepeatNote=2-5
TgeneSONchr15:75977076chr21:34945612ENST000003565777121981_198722952427.0RepeatNote=2-6
TgeneSONchr15:75977076chr21:34945612ENST000003565777121988_199422952427.0RepeatNote=2-7
TgeneSONchr15:75977076chr21:34945612ENST000003565777121995_201322952427.0RepeatNote=3-2


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Fusion Gene Sequence for CSPG4-SON


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>19903_19903_1_CSPG4-SON_CSPG4_chr15_75977076_ENST00000308508_SON_chr21_34945612_ENST00000290239_length(transcript)=6020nt_BP=4542nt
GCGCCCAGGAGCAGAGCCGCGCTCGCTCCACTCAGCTCCCAGCTCCCAGGACTCCGCTGGCTCCTCGCAAGTCCTGCCGCCCAGCCCGCC
GGGATGCAGTCCGGGCCGCGGCCCCCACTTCCAGCCCCCGGCCTGGCCTTGGCTTTGACCCTGACTATGTTGGCCAGACTTGCATCCGCG
GCTTCCTTCTTCGGTGAGAACCACCTGGAGGTGCCTGTGGCCACGGCTCTGACCGACATAGACCTGCAGCTGCAGTTCTCCACGTCCCAG
CCCGAAGCCCTCCTTCTCCTGGCAGCAGGCCCAGCTGACCACCTCCTGCTGCAGCTCTACTCTGGACGCCTGCAGGTCAGACTTGTTCTG
GGCCAGGAGGAGCTGAGGCTGCAGACTCCAGCAGAGACGCTGCTGAGTGACTCCATCCCCCACACTGTGGTGCTGACTGTCGTAGAGGGC
TGGGCCACGTTGTCAGTCGATGGGTTTCTGAACGCCTCCTCAGCAGTCCCAGGAGCCCCCCTAGAGGTCCCCTATGGGCTCTTTGTTGGG
GGCACTGGGACCCTTGGCCTGCCCTACCTGAGGGGAACCAGCCGACCCCTGAGGGGTTGCCTCCATGCAGCCACCCTCAATGGCCGCAGC
CTCCTCCGGCCTCTGACCCCCGATGTGCATGAGGGCTGTGCTGAAGAGTTTTCTGCCAGTGATGATGTGGCCCTGGGCTTCTCTGGGCCC
CACTCTCTGGCTGCCTTCCCTGCCTGGGGCACTCAGGACGAAGGAACCCTAGAGTTTACACTCACCACACAGAGCCGGCAGGCACCCTTG
GCCTTCCAGGCAGGGGGCCGGCGTGGGGACTTCATCTATGTGGACATATTTGAGGGCCACCTGCGGGCCGTGGTGGAGAAGGGCCAGGGT
ACCGTATTGCTCCACAACAGTGTGCCTGTGGCCGATGGGCAGCCCCATGAGGTCAGTGTCCACATCAATGCTCACCGGCTGGAAATCTCC
GTGGACCAGTACCCTACGCATACTTCGAACCGAGGAGTCCTCAGCTACCTGGAGCCACGGGGCAGTCTCCTTCTCGGGGGGCTGGATGCA
GAGGCCTCTCGTCACCTCCAGGAACACCGCCTGGGCCTGACACCAGAGGCCACCAATGCCTCCCTGCTGGGCTGCATGGAAGACCTCAGT
GTCAATGGCCAGAGGCGGGGGCTGCGGGAAGCTTTGCTGACGCGCAACATGGCAGCCGGCTGCAGGCTGGAGGAGGAGGAGTATGAGGAC
GATGCCTATGGACATTATGAAGCTTTCTCCACCCTGGCCCCTGAGGCTTGGCCAGCCATGGAGCTGCCTGAGCCATGCGTGCCTGAGCCA
GGGCTGCCTCCTGTCTTTGCCAATTTCACCCAGCTGCTGACTATCAGCCCACTGGTGGTGGCCGAGGGGGGCACAGCCTGGCTTGAGTGG
AGGCATGTGCAGCCCACGCTGGACCTGATGGAGGCTGAGCTGCGCAAATCCCAGGTGCTGTTCAGCGTGACCCGAGGGGCACGCCATGGC
GAGCTCGAGCTGGACATCCCGGGAGCCCAGGCACGAAAAATGTTCACCCTCCTGGACGTGGTGAACCGCAAGGCCCGCTTCATCCACGAT
GGCTCTGAGGACACCTCCGACCAGCTGGTGCTGGAGGTGTCGGTGACGGCTCGGGTGCCCATGCCCTCATGCCTTCGGAGGGGCCAAACA
TACCTCCTGCCCATCCAGGTCAACCCTGTCAATGACCCACCCCACATCATCTTCCCACATGGCAGCCTCATGGTGATCCTGGAACACACG
CAGAAGCCGCTGGGGCCTGAGGTTTTCCAGGCCTATGACCCGGACTCTGCCTGTGAGGGCCTCACCTTCCAGGTCCTTGGCACCTCCTCT
GGCCTCCCCGTGGAGCGCCGAGACCAGCCTGGGGAGCCGGCGACCGAGTTCTCCTGCCGGGAGTTGGAGGCCGGCAGCCTAGTCTATGTC
CACCGCGGTGGTCCTGCACAGGACTTGACGTTCCGGGTCAGCGATGGACTGCAGGCCAGCCCCCCGGCCACGCTGAAGGTGGTGGCCATC
CGGCCGGCCATACAGATCCACCGCAGCACAGGGTTGCGACTGGCCCAAGGCTCTGCCATGCCCATCTTGCCCGCCAACCTGTCGGTGGAG
ACCAATGCCGTGGGGCAGGATGTGAGCGTGCTGTTCCGCGTCACTGGGGCCCTGCAGTTTGGGGAGCTGCAGAAGCAGGGGGCAGGTGGG
GTGGAGGGTGCTGAGTGGTGGGCCACACAGGCGTTCCACCAGCGGGATGTGGAGCAGGGCCGCGTGAGGTACCTGAGCACTGACCCACAG
CACCACGCTTACGACACCGTGGAGAACCTGGCCCTGGAGGTGCAGGTGGGCCAGGAGATCCTGAGCAATCTGTCCTTCCCAGTGACCATC
CAGAGAGCCACTGTGTGGATGCTGCGGCTGGAGCCACTGCACACTCAGAACACCCAGCAGGAGACCCTCACCACAGCCCACCTGGAGGCC
ACCCTGGAGGAGGCAGGCCCAAGCCCCCCAACCTTCCATTATGAGGTGGTTCAGGCTCCCAGGAAAGGCAACCTTCAACTACAGGGCACA
AGGCTGTCAGATGGCCAGGGCTTCACCCAGGATGACATACAGGCTGGCCGGGTGACCTATGGGGCCACAGCACGTGCCTCAGAGGCAGTC
GAGGACACCTTCCGTTTCCGTGTCACAGCTCCACCATATTTCTCCCCACTCTATACCTTCCCCATCCACATTGGTGGTGACCCAGATGCG
CCTGTCCTCACCAATGTCCTCCTCGTGGTGCCTGAGGGTGGTGAGGGTGTCCTCTCTGCTGACCACCTCTTTGTCAAGAGTCTCAACAGT
GCCAGCTACCTCTATGAGGTCATGGAGCGGCCCCGCCATGGGAGGTTGGCTTGGCGTGGGACACAGGACAAGACCACTATGGTGACATCC
TTCACCAATGAAGACCTGTTGCGTGGCCGGCTGGTCTACCAGCATGATGACTCCGAGACCACAGAAGATGATATCCCATTTGTTGCTACC
CGCCAGGGCGAGAGCAGTGGTGACATGGCCTGGGAGGAGGTACGGGGTGTCTTCCGAGTGGCCATCCAGCCCGTGAATGACCACGCCCCT
GTGCAGACCATCAGCCGGATCTTCCATGTGGCCCGGGGTGGGCGGCGGCTGCTGACTACAGACGACGTGGCCTTCAGCGATGCTGACTCG
GGCTTTGCTGACGCCCAGCTGGTGCTTACCCGCAAGGACCTCCTCTTTGGCAGTATCGTGGCCGTAGATGAGCCCACGCGGCCCATCTAC
CGCTTCACCCAGGAGGACCTCAGGAAGAGGCGAGTACTGTTCGTGCACTCAGGGGCTGACCGTGGCTGGATCCAGCTGCAGGTGTCCGAC
GGGCAACACCAGGCCACTGCGCTGCTGGAGGTGCAGGCCTCGGAACCCTACCTCCGTGTGGCCAACGGCTCCAGCCTTGTGGTCCCTCAA
GGAGGCCAGGGCACCATCGACACGGCCGTGCTCCACCTGGACACCAACCTCGACATCCGCAGTGGGGATGAGGTCCACTACCACGTCACA
GCTGGCCCTCGCTGGGGACAGCTAGTCCGGGCTGGTCAGCCAGCCACAGCCTTCTCCCAGCAGGACCTGCTGGATGGGGCCGTTCTCTAT
AGCCACAATGGCAGCCTCAGCCCCCGCGACACCATGGCCTTCTCCGTGGAAGCAGGGCCAGTGCACACGGATGCCACCCTACAAGTGACC
ATTGCCCTAGAGGGCCCACTGGCCCCACTGAAGCTGGTCCGGCACAAGAAGATCTACGTCTTCCAGGGAGAGGCAGCTGAGATCAGAAGG
GACCAGCTGGAGGCAGCCCAGGAGGCAGTGCCACCTGCAGACATCGTATTCTCAGTGAAGAGCCCACCGAGTGCCGGCTACCTGGTGATG
GTGTCGCGTGGCGCCTTGGCAGATGAGCCACCCAGCCTGGACCCTGTGCAGAGCTTCTCCCAGGAGGCAGTGGACACAGGCAGGGTCCTG
TACCTGCACTCCCGCCCTGAGGCCTGGAGCGATGCCTTCTCGCTGGATGTGGCCTCAGGCCTGGGTGCTCCCCTCGAGGGCGTCCTTGTG
GAGCTGGAGGTGCTGCCCGCTGCCATCCCACTAGAGGCGCAAAACTTCAGCGTCCCTGAGGGTGGCAGCCTCACCCTGGCCCCTCCACTG
CTCCGTGTCTCCGGGCCCTACTTCCCCACTCTCCTGGGCCTCAGCCTGCAGGTGCTGGAGCCACCCCAGCATGGAGCCCTGCAGAAGGAG
GACGGACCTCAAGCCAGGACCCTCAGCGCCTTCTCCTGGAGAATGGTGGAAGAGCAGCTGATCCGCTACGTGCATGACGGGAGCGAGACA
CTGACAGACAGTTTTGTCCTGATGGCTAATGCCTCCGAGATGGATCGCCAGAGCCATCCTGTGGCCTTCACTGTCACTGTCCTGCCTGTC
AATGACCAACCCCCCATCCTCACTACAAACACAGGCCTGCAGGATCAGTTCTTAAGAGCAGCCCCGGTAACTGGAGGAATGGGAGCCGTT
TTGATGAGAAAAATGGGCTGGAGAGAAGGAGAAGGATTAGGAAAAAACAAAGAAGGCAATAAGGAACCCATCCTAGTTGATTTTAAGACA
GACCGAAAAGGTCTTGTTGCAGTAGGAGAAAGAGCACAAAAGAGGTCTGGGAACTTCTCTGCTGCAATGAAAGATCTGTCAGGCAAACAT
CCTGTGTCTGCTTTGATGGAGATCTGTAATAAAAGAAGGTGGCAACCACCTGAATTTCTATTGGTCCATGATAGTGGCCCTGATCATCGC
AAACATTTTCTCTTTAGGGTATTGAGAAATGGAGCCCTTACCAGACCCAATTGTATGTTTTTCTTGAATAGGTATTGATAAATGGAAGCG
CTTACCAGCCCAGCTTTGCCAGCCCTAATAAGAAGCATGCTAAAGCCACAGCAGCTACTGTGGTTCTTCAAGCAATGGGCCTTGTACCAA
AGGACCTCATGGCTAATGCCACTTGCTTCAGGAGTGCCTCACGTAGATAGATTGAGGTTTTATAATAATCATTTCAGAATTTTACTCTGC
ATCACAATGTATTTCCTCTTTAATGTTGTAAATATTTGGCAATTTAAGACATTGTGTAAAAAGCAATCTGTAAAAACATCTCCAGGCTTT
GATTTTTGTACCATGGAAATTGTATTTAACCATACAGGGTTTTGGTATGTTTATATTGTTTACCTTAGTGATGTATTTGTTTAAGTGGCT
AACATCCAAACGACTGTTTGAAGGCATCAGAGTAATCTTCAGTGTGGAATGTTAAATAACGCTTTTATACTGTATTTTGTACTATGATGT
AACTCCCCTTCCTTATGGCTAGGCTACTGTAACACTTGCCTGTAATCAGTGAAGGGCTGTGCACCTTGTACTATTTCACAATGGGTTCTG
CTGGACAGATAATGGGCCAGTGTTATTGAGGTGATCAAGATCTGTTCCACAGGGCTAATGCCACCATCTCCCCTCAAAATTTTGTAGAGG
TTCTAAAAAGAAAGTGGTATGTTGTGTGATGATCAGCACTAAGTCCTGCATTCCTGTTAAAGCCACTTGGGTCATAAGAAGGGAGTAAAA
AATGAAGTCTGACTAGAATTCTATTGCAGAGGCCAGTACATTTAGTATGGCATTGAGTTGTGATATAGTTTTACTTTGATGTGCATTTTG
AATTTCAGCTACACCTAGATAGACGTAAAATGATAATTAAAATGCTGTAACCAACTTATCTAATAAAATTGGCAACCAGCCACTATTTTG
TTGACTATGAGAAAGTTAAAAGTTTATGTTAATTTTTAGGGTCTGATAGAATATTTCATGTGTATTACAGTGGTATTCATATGCTATGTC

>19903_19903_1_CSPG4-SON_CSPG4_chr15_75977076_ENST00000308508_SON_chr21_34945612_ENST00000290239_length(amino acids)=1614AA_BP=1483
MQSGPRPPLPAPGLALALTLTMLARLASAASFFGENHLEVPVATALTDIDLQLQFSTSQPEALLLLAAGPADHLLLQLYSGRLQVRLVLG
QEELRLQTPAETLLSDSIPHTVVLTVVEGWATLSVDGFLNASSAVPGAPLEVPYGLFVGGTGTLGLPYLRGTSRPLRGCLHAATLNGRSL
LRPLTPDVHEGCAEEFSASDDVALGFSGPHSLAAFPAWGTQDEGTLEFTLTTQSRQAPLAFQAGGRRGDFIYVDIFEGHLRAVVEKGQGT
VLLHNSVPVADGQPHEVSVHINAHRLEISVDQYPTHTSNRGVLSYLEPRGSLLLGGLDAEASRHLQEHRLGLTPEATNASLLGCMEDLSV
NGQRRGLREALLTRNMAAGCRLEEEEYEDDAYGHYEAFSTLAPEAWPAMELPEPCVPEPGLPPVFANFTQLLTISPLVVAEGGTAWLEWR
HVQPTLDLMEAELRKSQVLFSVTRGARHGELELDIPGAQARKMFTLLDVVNRKARFIHDGSEDTSDQLVLEVSVTARVPMPSCLRRGQTY
LLPIQVNPVNDPPHIIFPHGSLMVILEHTQKPLGPEVFQAYDPDSACEGLTFQVLGTSSGLPVERRDQPGEPATEFSCRELEAGSLVYVH
RGGPAQDLTFRVSDGLQASPPATLKVVAIRPAIQIHRSTGLRLAQGSAMPILPANLSVETNAVGQDVSVLFRVTGALQFGELQKQGAGGV
EGAEWWATQAFHQRDVEQGRVRYLSTDPQHHAYDTVENLALEVQVGQEILSNLSFPVTIQRATVWMLRLEPLHTQNTQQETLTTAHLEAT
LEEAGPSPPTFHYEVVQAPRKGNLQLQGTRLSDGQGFTQDDIQAGRVTYGATARASEAVEDTFRFRVTAPPYFSPLYTFPIHIGGDPDAP
VLTNVLLVVPEGGEGVLSADHLFVKSLNSASYLYEVMERPRHGRLAWRGTQDKTTMVTSFTNEDLLRGRLVYQHDDSETTEDDIPFVATR
QGESSGDMAWEEVRGVFRVAIQPVNDHAPVQTISRIFHVARGGRRLLTTDDVAFSDADSGFADAQLVLTRKDLLFGSIVAVDEPTRPIYR
FTQEDLRKRRVLFVHSGADRGWIQLQVSDGQHQATALLEVQASEPYLRVANGSSLVVPQGGQGTIDTAVLHLDTNLDIRSGDEVHYHVTA
GPRWGQLVRAGQPATAFSQQDLLDGAVLYSHNGSLSPRDTMAFSVEAGPVHTDATLQVTIALEGPLAPLKLVRHKKIYVFQGEAAEIRRD
QLEAAQEAVPPADIVFSVKSPPSAGYLVMVSRGALADEPPSLDPVQSFSQEAVDTGRVLYLHSRPEAWSDAFSLDVASGLGAPLEGVLVE
LEVLPAAIPLEAQNFSVPEGGSLTLAPPLLRVSGPYFPTLLGLSLQVLEPPQHGALQKEDGPQARTLSAFSWRMVEEQLIRYVHDGSETL
TDSFVLMANASEMDRQSHPVAFTVTVLPVNDQPPILTTNTGLQDQFLRAAPVTGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTD

--------------------------------------------------------------
>19903_19903_2_CSPG4-SON_CSPG4_chr15_75977076_ENST00000308508_SON_chr21_34945612_ENST00000356577_length(transcript)=5995nt_BP=4542nt
GCGCCCAGGAGCAGAGCCGCGCTCGCTCCACTCAGCTCCCAGCTCCCAGGACTCCGCTGGCTCCTCGCAAGTCCTGCCGCCCAGCCCGCC
GGGATGCAGTCCGGGCCGCGGCCCCCACTTCCAGCCCCCGGCCTGGCCTTGGCTTTGACCCTGACTATGTTGGCCAGACTTGCATCCGCG
GCTTCCTTCTTCGGTGAGAACCACCTGGAGGTGCCTGTGGCCACGGCTCTGACCGACATAGACCTGCAGCTGCAGTTCTCCACGTCCCAG
CCCGAAGCCCTCCTTCTCCTGGCAGCAGGCCCAGCTGACCACCTCCTGCTGCAGCTCTACTCTGGACGCCTGCAGGTCAGACTTGTTCTG
GGCCAGGAGGAGCTGAGGCTGCAGACTCCAGCAGAGACGCTGCTGAGTGACTCCATCCCCCACACTGTGGTGCTGACTGTCGTAGAGGGC
TGGGCCACGTTGTCAGTCGATGGGTTTCTGAACGCCTCCTCAGCAGTCCCAGGAGCCCCCCTAGAGGTCCCCTATGGGCTCTTTGTTGGG
GGCACTGGGACCCTTGGCCTGCCCTACCTGAGGGGAACCAGCCGACCCCTGAGGGGTTGCCTCCATGCAGCCACCCTCAATGGCCGCAGC
CTCCTCCGGCCTCTGACCCCCGATGTGCATGAGGGCTGTGCTGAAGAGTTTTCTGCCAGTGATGATGTGGCCCTGGGCTTCTCTGGGCCC
CACTCTCTGGCTGCCTTCCCTGCCTGGGGCACTCAGGACGAAGGAACCCTAGAGTTTACACTCACCACACAGAGCCGGCAGGCACCCTTG
GCCTTCCAGGCAGGGGGCCGGCGTGGGGACTTCATCTATGTGGACATATTTGAGGGCCACCTGCGGGCCGTGGTGGAGAAGGGCCAGGGT
ACCGTATTGCTCCACAACAGTGTGCCTGTGGCCGATGGGCAGCCCCATGAGGTCAGTGTCCACATCAATGCTCACCGGCTGGAAATCTCC
GTGGACCAGTACCCTACGCATACTTCGAACCGAGGAGTCCTCAGCTACCTGGAGCCACGGGGCAGTCTCCTTCTCGGGGGGCTGGATGCA
GAGGCCTCTCGTCACCTCCAGGAACACCGCCTGGGCCTGACACCAGAGGCCACCAATGCCTCCCTGCTGGGCTGCATGGAAGACCTCAGT
GTCAATGGCCAGAGGCGGGGGCTGCGGGAAGCTTTGCTGACGCGCAACATGGCAGCCGGCTGCAGGCTGGAGGAGGAGGAGTATGAGGAC
GATGCCTATGGACATTATGAAGCTTTCTCCACCCTGGCCCCTGAGGCTTGGCCAGCCATGGAGCTGCCTGAGCCATGCGTGCCTGAGCCA
GGGCTGCCTCCTGTCTTTGCCAATTTCACCCAGCTGCTGACTATCAGCCCACTGGTGGTGGCCGAGGGGGGCACAGCCTGGCTTGAGTGG
AGGCATGTGCAGCCCACGCTGGACCTGATGGAGGCTGAGCTGCGCAAATCCCAGGTGCTGTTCAGCGTGACCCGAGGGGCACGCCATGGC
GAGCTCGAGCTGGACATCCCGGGAGCCCAGGCACGAAAAATGTTCACCCTCCTGGACGTGGTGAACCGCAAGGCCCGCTTCATCCACGAT
GGCTCTGAGGACACCTCCGACCAGCTGGTGCTGGAGGTGTCGGTGACGGCTCGGGTGCCCATGCCCTCATGCCTTCGGAGGGGCCAAACA
TACCTCCTGCCCATCCAGGTCAACCCTGTCAATGACCCACCCCACATCATCTTCCCACATGGCAGCCTCATGGTGATCCTGGAACACACG
CAGAAGCCGCTGGGGCCTGAGGTTTTCCAGGCCTATGACCCGGACTCTGCCTGTGAGGGCCTCACCTTCCAGGTCCTTGGCACCTCCTCT
GGCCTCCCCGTGGAGCGCCGAGACCAGCCTGGGGAGCCGGCGACCGAGTTCTCCTGCCGGGAGTTGGAGGCCGGCAGCCTAGTCTATGTC
CACCGCGGTGGTCCTGCACAGGACTTGACGTTCCGGGTCAGCGATGGACTGCAGGCCAGCCCCCCGGCCACGCTGAAGGTGGTGGCCATC
CGGCCGGCCATACAGATCCACCGCAGCACAGGGTTGCGACTGGCCCAAGGCTCTGCCATGCCCATCTTGCCCGCCAACCTGTCGGTGGAG
ACCAATGCCGTGGGGCAGGATGTGAGCGTGCTGTTCCGCGTCACTGGGGCCCTGCAGTTTGGGGAGCTGCAGAAGCAGGGGGCAGGTGGG
GTGGAGGGTGCTGAGTGGTGGGCCACACAGGCGTTCCACCAGCGGGATGTGGAGCAGGGCCGCGTGAGGTACCTGAGCACTGACCCACAG
CACCACGCTTACGACACCGTGGAGAACCTGGCCCTGGAGGTGCAGGTGGGCCAGGAGATCCTGAGCAATCTGTCCTTCCCAGTGACCATC
CAGAGAGCCACTGTGTGGATGCTGCGGCTGGAGCCACTGCACACTCAGAACACCCAGCAGGAGACCCTCACCACAGCCCACCTGGAGGCC
ACCCTGGAGGAGGCAGGCCCAAGCCCCCCAACCTTCCATTATGAGGTGGTTCAGGCTCCCAGGAAAGGCAACCTTCAACTACAGGGCACA
AGGCTGTCAGATGGCCAGGGCTTCACCCAGGATGACATACAGGCTGGCCGGGTGACCTATGGGGCCACAGCACGTGCCTCAGAGGCAGTC
GAGGACACCTTCCGTTTCCGTGTCACAGCTCCACCATATTTCTCCCCACTCTATACCTTCCCCATCCACATTGGTGGTGACCCAGATGCG
CCTGTCCTCACCAATGTCCTCCTCGTGGTGCCTGAGGGTGGTGAGGGTGTCCTCTCTGCTGACCACCTCTTTGTCAAGAGTCTCAACAGT
GCCAGCTACCTCTATGAGGTCATGGAGCGGCCCCGCCATGGGAGGTTGGCTTGGCGTGGGACACAGGACAAGACCACTATGGTGACATCC
TTCACCAATGAAGACCTGTTGCGTGGCCGGCTGGTCTACCAGCATGATGACTCCGAGACCACAGAAGATGATATCCCATTTGTTGCTACC
CGCCAGGGCGAGAGCAGTGGTGACATGGCCTGGGAGGAGGTACGGGGTGTCTTCCGAGTGGCCATCCAGCCCGTGAATGACCACGCCCCT
GTGCAGACCATCAGCCGGATCTTCCATGTGGCCCGGGGTGGGCGGCGGCTGCTGACTACAGACGACGTGGCCTTCAGCGATGCTGACTCG
GGCTTTGCTGACGCCCAGCTGGTGCTTACCCGCAAGGACCTCCTCTTTGGCAGTATCGTGGCCGTAGATGAGCCCACGCGGCCCATCTAC
CGCTTCACCCAGGAGGACCTCAGGAAGAGGCGAGTACTGTTCGTGCACTCAGGGGCTGACCGTGGCTGGATCCAGCTGCAGGTGTCCGAC
GGGCAACACCAGGCCACTGCGCTGCTGGAGGTGCAGGCCTCGGAACCCTACCTCCGTGTGGCCAACGGCTCCAGCCTTGTGGTCCCTCAA
GGAGGCCAGGGCACCATCGACACGGCCGTGCTCCACCTGGACACCAACCTCGACATCCGCAGTGGGGATGAGGTCCACTACCACGTCACA
GCTGGCCCTCGCTGGGGACAGCTAGTCCGGGCTGGTCAGCCAGCCACAGCCTTCTCCCAGCAGGACCTGCTGGATGGGGCCGTTCTCTAT
AGCCACAATGGCAGCCTCAGCCCCCGCGACACCATGGCCTTCTCCGTGGAAGCAGGGCCAGTGCACACGGATGCCACCCTACAAGTGACC
ATTGCCCTAGAGGGCCCACTGGCCCCACTGAAGCTGGTCCGGCACAAGAAGATCTACGTCTTCCAGGGAGAGGCAGCTGAGATCAGAAGG
GACCAGCTGGAGGCAGCCCAGGAGGCAGTGCCACCTGCAGACATCGTATTCTCAGTGAAGAGCCCACCGAGTGCCGGCTACCTGGTGATG
GTGTCGCGTGGCGCCTTGGCAGATGAGCCACCCAGCCTGGACCCTGTGCAGAGCTTCTCCCAGGAGGCAGTGGACACAGGCAGGGTCCTG
TACCTGCACTCCCGCCCTGAGGCCTGGAGCGATGCCTTCTCGCTGGATGTGGCCTCAGGCCTGGGTGCTCCCCTCGAGGGCGTCCTTGTG
GAGCTGGAGGTGCTGCCCGCTGCCATCCCACTAGAGGCGCAAAACTTCAGCGTCCCTGAGGGTGGCAGCCTCACCCTGGCCCCTCCACTG
CTCCGTGTCTCCGGGCCCTACTTCCCCACTCTCCTGGGCCTCAGCCTGCAGGTGCTGGAGCCACCCCAGCATGGAGCCCTGCAGAAGGAG
GACGGACCTCAAGCCAGGACCCTCAGCGCCTTCTCCTGGAGAATGGTGGAAGAGCAGCTGATCCGCTACGTGCATGACGGGAGCGAGACA
CTGACAGACAGTTTTGTCCTGATGGCTAATGCCTCCGAGATGGATCGCCAGAGCCATCCTGTGGCCTTCACTGTCACTGTCCTGCCTGTC
AATGACCAACCCCCCATCCTCACTACAAACACAGGCCTGCAGGATCAGTTCTTAAGAGCAGCCCCGGTAACTGGAGGAATGGGAGCCGTT
TTGATGAGAAAAATGGGCTGGAGAGAAGGAGAAGGATTAGGAAAAAACAAAGAAGGCAATAAGGAACCCATCCTAGTTGATTTTAAGACA
GACCGAAAAGGTCTTGTTGCAGTAGGAGAAAGAGCACAAAAGAGGTCTGGGAACTTCTCTGCTGCAATGAAAGATCTGTCAGGCAAACAT
CCTGTGTCTGCTTTGATGGAGATCTGTAATAAAAGAAGGTGGCAACCACCTGAATTTCTATTGGTCCATGATAGTGGCCCTGATCATCGC
AAACATTTTCTCTTTAGGGTATTGAGAAATGGAGCCCTTACCAGACCCAATTGTATGTTTTTCTTGAATAGGTATTGATAAATGGAAGCG
CTTACCAGCCCAGCTTTGCCAGCCCTAATAAGAAGCATGCTAAAGCCACAGCAGCTACTGTGGTTCTTCAAGCAATGGGCCTTGTACCAA
AGGACCTCATGGCTAATGCCACTTGCTTCAGGAGTGCCTCACGTAGATAGATTGAGGTTTTATAATAATCATTTCAGAATTTTACTCTGC
ATCACAATGTATTTCCTCTTTAATGTTGTAAATATTTGGCAATTTAAGACATTGTGTAAAAAGCAATCTGTAAAAACATCTCCAGGCTTT
GATTTTTGTACCATGGAAATTGTATTTAACCATACAGGGTTTTGGTATGTTTATATTGTTTACCTTAGTGATGTATTTGTTTAAGTGGCT
AACATCCAAACGACTGTTTGAAGGCATCAGAGTAATCTTCAGTGTGGAATGTTAAATAACGCTTTTATACTGTATTTTGTACTATGATGT
AACTCCCCTTCCTTATGGCTAGGCTACTGTAACACTTGCCTGTAATCAGTGAAGGGCTGTGCACCTTGTACTATTTCACAATGGGTTCTG
CTGGACAGATAATGGGCCAGTGTTATTGAGGTGATCAAGATCTGTTCCACAGGGCTAATGCCACCATCTCCCCTCAAAATTTTGTAGAGG
TTCTAAAAAGAAAGTGGTATGTTGTGTGATGATCAGCACTAAGTCCTGCATTCCTGTTAAAGCCACTTGGGTCATAAGAAGGGAGTAAAA
AATGAAGTCTGACTAGAATTCTATTGCAGAGGCCAGTACATTTAGTATGGCATTGAGTTGTGATATAGTTTTACTTTGATGTGCATTTTG
AATTTCAGCTACACCTAGATAGACGTAAAATGATAATTAAAATGCTGTAACCAACTTATCTAATAAAATTGGCAACCAGCCACTATTTTG
TTGACTATGAGAAAGTTAAAAGTTTATGTTAATTTTTAGGGTCTGATAGAATATTTCATGTGTATTACAGTGGTATTCATATGCTATGTC

>19903_19903_2_CSPG4-SON_CSPG4_chr15_75977076_ENST00000308508_SON_chr21_34945612_ENST00000356577_length(amino acids)=1614AA_BP=1483
MQSGPRPPLPAPGLALALTLTMLARLASAASFFGENHLEVPVATALTDIDLQLQFSTSQPEALLLLAAGPADHLLLQLYSGRLQVRLVLG
QEELRLQTPAETLLSDSIPHTVVLTVVEGWATLSVDGFLNASSAVPGAPLEVPYGLFVGGTGTLGLPYLRGTSRPLRGCLHAATLNGRSL
LRPLTPDVHEGCAEEFSASDDVALGFSGPHSLAAFPAWGTQDEGTLEFTLTTQSRQAPLAFQAGGRRGDFIYVDIFEGHLRAVVEKGQGT
VLLHNSVPVADGQPHEVSVHINAHRLEISVDQYPTHTSNRGVLSYLEPRGSLLLGGLDAEASRHLQEHRLGLTPEATNASLLGCMEDLSV
NGQRRGLREALLTRNMAAGCRLEEEEYEDDAYGHYEAFSTLAPEAWPAMELPEPCVPEPGLPPVFANFTQLLTISPLVVAEGGTAWLEWR
HVQPTLDLMEAELRKSQVLFSVTRGARHGELELDIPGAQARKMFTLLDVVNRKARFIHDGSEDTSDQLVLEVSVTARVPMPSCLRRGQTY
LLPIQVNPVNDPPHIIFPHGSLMVILEHTQKPLGPEVFQAYDPDSACEGLTFQVLGTSSGLPVERRDQPGEPATEFSCRELEAGSLVYVH
RGGPAQDLTFRVSDGLQASPPATLKVVAIRPAIQIHRSTGLRLAQGSAMPILPANLSVETNAVGQDVSVLFRVTGALQFGELQKQGAGGV
EGAEWWATQAFHQRDVEQGRVRYLSTDPQHHAYDTVENLALEVQVGQEILSNLSFPVTIQRATVWMLRLEPLHTQNTQQETLTTAHLEAT
LEEAGPSPPTFHYEVVQAPRKGNLQLQGTRLSDGQGFTQDDIQAGRVTYGATARASEAVEDTFRFRVTAPPYFSPLYTFPIHIGGDPDAP
VLTNVLLVVPEGGEGVLSADHLFVKSLNSASYLYEVMERPRHGRLAWRGTQDKTTMVTSFTNEDLLRGRLVYQHDDSETTEDDIPFVATR
QGESSGDMAWEEVRGVFRVAIQPVNDHAPVQTISRIFHVARGGRRLLTTDDVAFSDADSGFADAQLVLTRKDLLFGSIVAVDEPTRPIYR
FTQEDLRKRRVLFVHSGADRGWIQLQVSDGQHQATALLEVQASEPYLRVANGSSLVVPQGGQGTIDTAVLHLDTNLDIRSGDEVHYHVTA
GPRWGQLVRAGQPATAFSQQDLLDGAVLYSHNGSLSPRDTMAFSVEAGPVHTDATLQVTIALEGPLAPLKLVRHKKIYVFQGEAAEIRRD
QLEAAQEAVPPADIVFSVKSPPSAGYLVMVSRGALADEPPSLDPVQSFSQEAVDTGRVLYLHSRPEAWSDAFSLDVASGLGAPLEGVLVE
LEVLPAAIPLEAQNFSVPEGGSLTLAPPLLRVSGPYFPTLLGLSLQVLEPPQHGALQKEDGPQARTLSAFSWRMVEEQLIRYVHDGSETL
TDSFVLMANASEMDRQSHPVAFTVTVLPVNDQPPILTTNTGLQDQFLRAAPVTGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTD

--------------------------------------------------------------
>19903_19903_3_CSPG4-SON_CSPG4_chr15_75977076_ENST00000308508_SON_chr21_34945612_ENST00000381692_length(transcript)=5995nt_BP=4542nt
GCGCCCAGGAGCAGAGCCGCGCTCGCTCCACTCAGCTCCCAGCTCCCAGGACTCCGCTGGCTCCTCGCAAGTCCTGCCGCCCAGCCCGCC
GGGATGCAGTCCGGGCCGCGGCCCCCACTTCCAGCCCCCGGCCTGGCCTTGGCTTTGACCCTGACTATGTTGGCCAGACTTGCATCCGCG
GCTTCCTTCTTCGGTGAGAACCACCTGGAGGTGCCTGTGGCCACGGCTCTGACCGACATAGACCTGCAGCTGCAGTTCTCCACGTCCCAG
CCCGAAGCCCTCCTTCTCCTGGCAGCAGGCCCAGCTGACCACCTCCTGCTGCAGCTCTACTCTGGACGCCTGCAGGTCAGACTTGTTCTG
GGCCAGGAGGAGCTGAGGCTGCAGACTCCAGCAGAGACGCTGCTGAGTGACTCCATCCCCCACACTGTGGTGCTGACTGTCGTAGAGGGC
TGGGCCACGTTGTCAGTCGATGGGTTTCTGAACGCCTCCTCAGCAGTCCCAGGAGCCCCCCTAGAGGTCCCCTATGGGCTCTTTGTTGGG
GGCACTGGGACCCTTGGCCTGCCCTACCTGAGGGGAACCAGCCGACCCCTGAGGGGTTGCCTCCATGCAGCCACCCTCAATGGCCGCAGC
CTCCTCCGGCCTCTGACCCCCGATGTGCATGAGGGCTGTGCTGAAGAGTTTTCTGCCAGTGATGATGTGGCCCTGGGCTTCTCTGGGCCC
CACTCTCTGGCTGCCTTCCCTGCCTGGGGCACTCAGGACGAAGGAACCCTAGAGTTTACACTCACCACACAGAGCCGGCAGGCACCCTTG
GCCTTCCAGGCAGGGGGCCGGCGTGGGGACTTCATCTATGTGGACATATTTGAGGGCCACCTGCGGGCCGTGGTGGAGAAGGGCCAGGGT
ACCGTATTGCTCCACAACAGTGTGCCTGTGGCCGATGGGCAGCCCCATGAGGTCAGTGTCCACATCAATGCTCACCGGCTGGAAATCTCC
GTGGACCAGTACCCTACGCATACTTCGAACCGAGGAGTCCTCAGCTACCTGGAGCCACGGGGCAGTCTCCTTCTCGGGGGGCTGGATGCA
GAGGCCTCTCGTCACCTCCAGGAACACCGCCTGGGCCTGACACCAGAGGCCACCAATGCCTCCCTGCTGGGCTGCATGGAAGACCTCAGT
GTCAATGGCCAGAGGCGGGGGCTGCGGGAAGCTTTGCTGACGCGCAACATGGCAGCCGGCTGCAGGCTGGAGGAGGAGGAGTATGAGGAC
GATGCCTATGGACATTATGAAGCTTTCTCCACCCTGGCCCCTGAGGCTTGGCCAGCCATGGAGCTGCCTGAGCCATGCGTGCCTGAGCCA
GGGCTGCCTCCTGTCTTTGCCAATTTCACCCAGCTGCTGACTATCAGCCCACTGGTGGTGGCCGAGGGGGGCACAGCCTGGCTTGAGTGG
AGGCATGTGCAGCCCACGCTGGACCTGATGGAGGCTGAGCTGCGCAAATCCCAGGTGCTGTTCAGCGTGACCCGAGGGGCACGCCATGGC
GAGCTCGAGCTGGACATCCCGGGAGCCCAGGCACGAAAAATGTTCACCCTCCTGGACGTGGTGAACCGCAAGGCCCGCTTCATCCACGAT
GGCTCTGAGGACACCTCCGACCAGCTGGTGCTGGAGGTGTCGGTGACGGCTCGGGTGCCCATGCCCTCATGCCTTCGGAGGGGCCAAACA
TACCTCCTGCCCATCCAGGTCAACCCTGTCAATGACCCACCCCACATCATCTTCCCACATGGCAGCCTCATGGTGATCCTGGAACACACG
CAGAAGCCGCTGGGGCCTGAGGTTTTCCAGGCCTATGACCCGGACTCTGCCTGTGAGGGCCTCACCTTCCAGGTCCTTGGCACCTCCTCT
GGCCTCCCCGTGGAGCGCCGAGACCAGCCTGGGGAGCCGGCGACCGAGTTCTCCTGCCGGGAGTTGGAGGCCGGCAGCCTAGTCTATGTC
CACCGCGGTGGTCCTGCACAGGACTTGACGTTCCGGGTCAGCGATGGACTGCAGGCCAGCCCCCCGGCCACGCTGAAGGTGGTGGCCATC
CGGCCGGCCATACAGATCCACCGCAGCACAGGGTTGCGACTGGCCCAAGGCTCTGCCATGCCCATCTTGCCCGCCAACCTGTCGGTGGAG
ACCAATGCCGTGGGGCAGGATGTGAGCGTGCTGTTCCGCGTCACTGGGGCCCTGCAGTTTGGGGAGCTGCAGAAGCAGGGGGCAGGTGGG
GTGGAGGGTGCTGAGTGGTGGGCCACACAGGCGTTCCACCAGCGGGATGTGGAGCAGGGCCGCGTGAGGTACCTGAGCACTGACCCACAG
CACCACGCTTACGACACCGTGGAGAACCTGGCCCTGGAGGTGCAGGTGGGCCAGGAGATCCTGAGCAATCTGTCCTTCCCAGTGACCATC
CAGAGAGCCACTGTGTGGATGCTGCGGCTGGAGCCACTGCACACTCAGAACACCCAGCAGGAGACCCTCACCACAGCCCACCTGGAGGCC
ACCCTGGAGGAGGCAGGCCCAAGCCCCCCAACCTTCCATTATGAGGTGGTTCAGGCTCCCAGGAAAGGCAACCTTCAACTACAGGGCACA
AGGCTGTCAGATGGCCAGGGCTTCACCCAGGATGACATACAGGCTGGCCGGGTGACCTATGGGGCCACAGCACGTGCCTCAGAGGCAGTC
GAGGACACCTTCCGTTTCCGTGTCACAGCTCCACCATATTTCTCCCCACTCTATACCTTCCCCATCCACATTGGTGGTGACCCAGATGCG
CCTGTCCTCACCAATGTCCTCCTCGTGGTGCCTGAGGGTGGTGAGGGTGTCCTCTCTGCTGACCACCTCTTTGTCAAGAGTCTCAACAGT
GCCAGCTACCTCTATGAGGTCATGGAGCGGCCCCGCCATGGGAGGTTGGCTTGGCGTGGGACACAGGACAAGACCACTATGGTGACATCC
TTCACCAATGAAGACCTGTTGCGTGGCCGGCTGGTCTACCAGCATGATGACTCCGAGACCACAGAAGATGATATCCCATTTGTTGCTACC
CGCCAGGGCGAGAGCAGTGGTGACATGGCCTGGGAGGAGGTACGGGGTGTCTTCCGAGTGGCCATCCAGCCCGTGAATGACCACGCCCCT
GTGCAGACCATCAGCCGGATCTTCCATGTGGCCCGGGGTGGGCGGCGGCTGCTGACTACAGACGACGTGGCCTTCAGCGATGCTGACTCG
GGCTTTGCTGACGCCCAGCTGGTGCTTACCCGCAAGGACCTCCTCTTTGGCAGTATCGTGGCCGTAGATGAGCCCACGCGGCCCATCTAC
CGCTTCACCCAGGAGGACCTCAGGAAGAGGCGAGTACTGTTCGTGCACTCAGGGGCTGACCGTGGCTGGATCCAGCTGCAGGTGTCCGAC
GGGCAACACCAGGCCACTGCGCTGCTGGAGGTGCAGGCCTCGGAACCCTACCTCCGTGTGGCCAACGGCTCCAGCCTTGTGGTCCCTCAA
GGAGGCCAGGGCACCATCGACACGGCCGTGCTCCACCTGGACACCAACCTCGACATCCGCAGTGGGGATGAGGTCCACTACCACGTCACA
GCTGGCCCTCGCTGGGGACAGCTAGTCCGGGCTGGTCAGCCAGCCACAGCCTTCTCCCAGCAGGACCTGCTGGATGGGGCCGTTCTCTAT
AGCCACAATGGCAGCCTCAGCCCCCGCGACACCATGGCCTTCTCCGTGGAAGCAGGGCCAGTGCACACGGATGCCACCCTACAAGTGACC
ATTGCCCTAGAGGGCCCACTGGCCCCACTGAAGCTGGTCCGGCACAAGAAGATCTACGTCTTCCAGGGAGAGGCAGCTGAGATCAGAAGG
GACCAGCTGGAGGCAGCCCAGGAGGCAGTGCCACCTGCAGACATCGTATTCTCAGTGAAGAGCCCACCGAGTGCCGGCTACCTGGTGATG
GTGTCGCGTGGCGCCTTGGCAGATGAGCCACCCAGCCTGGACCCTGTGCAGAGCTTCTCCCAGGAGGCAGTGGACACAGGCAGGGTCCTG
TACCTGCACTCCCGCCCTGAGGCCTGGAGCGATGCCTTCTCGCTGGATGTGGCCTCAGGCCTGGGTGCTCCCCTCGAGGGCGTCCTTGTG
GAGCTGGAGGTGCTGCCCGCTGCCATCCCACTAGAGGCGCAAAACTTCAGCGTCCCTGAGGGTGGCAGCCTCACCCTGGCCCCTCCACTG
CTCCGTGTCTCCGGGCCCTACTTCCCCACTCTCCTGGGCCTCAGCCTGCAGGTGCTGGAGCCACCCCAGCATGGAGCCCTGCAGAAGGAG
GACGGACCTCAAGCCAGGACCCTCAGCGCCTTCTCCTGGAGAATGGTGGAAGAGCAGCTGATCCGCTACGTGCATGACGGGAGCGAGACA
CTGACAGACAGTTTTGTCCTGATGGCTAATGCCTCCGAGATGGATCGCCAGAGCCATCCTGTGGCCTTCACTGTCACTGTCCTGCCTGTC
AATGACCAACCCCCCATCCTCACTACAAACACAGGCCTGCAGGATCAGTTCTTAAGAGCAGCCCCGGTAACTGGAGGAATGGGAGCCGTT
TTGATGAGAAAAATGGGCTGGAGAGAAGGAGAAGGATTAGGAAAAAACAAAGAAGGCAATAAGGAACCCATCCTAGTTGATTTTAAGACA
GACCGAAAAGGTCTTGTTGCAGTAGGAGAAAGAGCACAAAAGAGGTCTGGGAACTTCTCTGCTGCAATGAAAGATCTGTCAGGCAAACAT
CCTGTGTCTGCTTTGATGGAGATCTGTAATAAAAGAAGGTGGCAACCACCTGAATTTCTATTGGTCCATGATAGTGGCCCTGATCATCGC
AAACATTTTCTCTTTAGGGTATTGAGAAATGGAGCCCTTACCAGACCCAATTGTATGTTTTTCTTGAATAGGTATTGATAAATGGAAGCG
CTTACCAGCCCAGCTTTGCCAGCCCTAATAAGAAGCATGCTAAAGCCACAGCAGCTACTGTGGTTCTTCAAGCAATGGGCCTTGTACCAA
AGGACCTCATGGCTAATGCCACTTGCTTCAGGAGTGCCTCACGTAGATAGATTGAGGTTTTATAATAATCATTTCAGAATTTTACTCTGC
ATCACAATGTATTTCCTCTTTAATGTTGTAAATATTTGGCAATTTAAGACATTGTGTAAAAAGCAATCTGTAAAAACATCTCCAGGCTTT
GATTTTTGTACCATGGAAATTGTATTTAACCATACAGGGTTTTGGTATGTTTATATTGTTTACCTTAGTGATGTATTTGTTTAAGTGGCT
AACATCCAAACGACTGTTTGAAGGCATCAGAGTAATCTTCAGTGTGGAATGTTAAATAACGCTTTTATACTGTATTTTGTACTATGATGT
AACTCCCCTTCCTTATGGCTAGGCTACTGTAACACTTGCCTGTAATCAGTGAAGGGCTGTGCACCTTGTACTATTTCACAATGGGTTCTG
CTGGACAGATAATGGGCCAGTGTTATTGAGGTGATCAAGATCTGTTCCACAGGGCTAATGCCACCATCTCCCCTCAAAATTTTGTAGAGG
TTCTAAAAAGAAAGTGGTATGTTGTGTGATGATCAGCACTAAGTCCTGCATTCCTGTTAAAGCCACTTGGGTCATAAGAAGGGAGTAAAA
AATGAAGTCTGACTAGAATTCTATTGCAGAGGCCAGTACATTTAGTATGGCATTGAGTTGTGATATAGTTTTACTTTGATGTGCATTTTG
AATTTCAGCTACACCTAGATAGACGTAAAATGATAATTAAAATGCTGTAACCAACTTATCTAATAAAATTGGCAACCAGCCACTATTTTG
TTGACTATGAGAAAGTTAAAAGTTTATGTTAATTTTTAGGGTCTGATAGAATATTTCATGTGTATTACAGTGGTATTCATATGCTATGTC

>19903_19903_3_CSPG4-SON_CSPG4_chr15_75977076_ENST00000308508_SON_chr21_34945612_ENST00000381692_length(amino acids)=1614AA_BP=1483
MQSGPRPPLPAPGLALALTLTMLARLASAASFFGENHLEVPVATALTDIDLQLQFSTSQPEALLLLAAGPADHLLLQLYSGRLQVRLVLG
QEELRLQTPAETLLSDSIPHTVVLTVVEGWATLSVDGFLNASSAVPGAPLEVPYGLFVGGTGTLGLPYLRGTSRPLRGCLHAATLNGRSL
LRPLTPDVHEGCAEEFSASDDVALGFSGPHSLAAFPAWGTQDEGTLEFTLTTQSRQAPLAFQAGGRRGDFIYVDIFEGHLRAVVEKGQGT
VLLHNSVPVADGQPHEVSVHINAHRLEISVDQYPTHTSNRGVLSYLEPRGSLLLGGLDAEASRHLQEHRLGLTPEATNASLLGCMEDLSV
NGQRRGLREALLTRNMAAGCRLEEEEYEDDAYGHYEAFSTLAPEAWPAMELPEPCVPEPGLPPVFANFTQLLTISPLVVAEGGTAWLEWR
HVQPTLDLMEAELRKSQVLFSVTRGARHGELELDIPGAQARKMFTLLDVVNRKARFIHDGSEDTSDQLVLEVSVTARVPMPSCLRRGQTY
LLPIQVNPVNDPPHIIFPHGSLMVILEHTQKPLGPEVFQAYDPDSACEGLTFQVLGTSSGLPVERRDQPGEPATEFSCRELEAGSLVYVH
RGGPAQDLTFRVSDGLQASPPATLKVVAIRPAIQIHRSTGLRLAQGSAMPILPANLSVETNAVGQDVSVLFRVTGALQFGELQKQGAGGV
EGAEWWATQAFHQRDVEQGRVRYLSTDPQHHAYDTVENLALEVQVGQEILSNLSFPVTIQRATVWMLRLEPLHTQNTQQETLTTAHLEAT
LEEAGPSPPTFHYEVVQAPRKGNLQLQGTRLSDGQGFTQDDIQAGRVTYGATARASEAVEDTFRFRVTAPPYFSPLYTFPIHIGGDPDAP
VLTNVLLVVPEGGEGVLSADHLFVKSLNSASYLYEVMERPRHGRLAWRGTQDKTTMVTSFTNEDLLRGRLVYQHDDSETTEDDIPFVATR
QGESSGDMAWEEVRGVFRVAIQPVNDHAPVQTISRIFHVARGGRRLLTTDDVAFSDADSGFADAQLVLTRKDLLFGSIVAVDEPTRPIYR
FTQEDLRKRRVLFVHSGADRGWIQLQVSDGQHQATALLEVQASEPYLRVANGSSLVVPQGGQGTIDTAVLHLDTNLDIRSGDEVHYHVTA
GPRWGQLVRAGQPATAFSQQDLLDGAVLYSHNGSLSPRDTMAFSVEAGPVHTDATLQVTIALEGPLAPLKLVRHKKIYVFQGEAAEIRRD
QLEAAQEAVPPADIVFSVKSPPSAGYLVMVSRGALADEPPSLDPVQSFSQEAVDTGRVLYLHSRPEAWSDAFSLDVASGLGAPLEGVLVE
LEVLPAAIPLEAQNFSVPEGGSLTLAPPLLRVSGPYFPTLLGLSLQVLEPPQHGALQKEDGPQARTLSAFSWRMVEEQLIRYVHDGSETL
TDSFVLMANASEMDRQSHPVAFTVTVLPVNDQPPILTTNTGLQDQFLRAAPVTGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTD

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CSPG4-SON


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-510631_14461483.02323.0COL5A1
HgeneCSPG4chr15:75977076chr21:34945612ENST00000308508-510574_10401483.02323.0COL6A2


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CSPG4-SON


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CSPG4-SON


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCSPG4C2239176Liver carcinoma1CTD_human
TgeneC4310696Zhu-Tokita-Takenouchi-Kim syndrome4CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC0010606Adenoid Cystic Carcinoma1CTD_human
TgeneC0036095Salivary Gland Neoplasms1CTD_human
TgeneC0220636Malignant neoplasm of salivary gland1CTD_human