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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:DOCK1-PPAPDC1A (FusionGDB2 ID:HG1793TG196051)

Fusion Gene Summary for DOCK1-PPAPDC1A

check button Fusion gene summary
Fusion gene informationFusion gene name: DOCK1-PPAPDC1A
Fusion gene ID: hg1793tg196051
HgeneTgene
Gene symbol

DOCK1

PPAPDC1A

Gene ID

1793

196051

Gene namededicator of cytokinesis 1phospholipid phosphatase 4
SynonymsDOCK180|ced5DPPL2|PPAPDC1|PPAPDC1A
Cytomap('DOCK1','DOCK1')('PLPP4','PPAPDC1A')

10q26.2

10q26.12

Type of geneprotein-codingprotein-coding
Descriptiondedicator of cytokinesis protein 1180 kDa protein downstream of CRKDOwnstream of CrKphospholipid phosphatase 4diacylglycerol pyrophosphate like 2diacylglycerol pyrophosphate phosphatase-like 2phosphatidate phosphatase PPAPDC1Aphosphatidic acid phosphatase type 2 domain containing 1Aphosphatidic acid phosphatase type 2 domain-contain
Modification date2020032720200313
UniProtAcc

Q14185

.
Ensembl transtripts involved in fusion geneENST00000280333, ENST00000484400, 
Fusion gene scores* DoF score17 X 17 X 11=31798 X 6 X 6=288
# samples 2013
** MAII scorelog2(20/3179*10)=-3.99050111136325
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/288*10)=-1.14755718841386
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DOCK1 [Title/Abstract] AND PPAPDC1A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDOCK1(128796513)-PPAPDC1A(122263330), # samples:2
DOCK1(128788867)-PLPP4(122263330), # samples:1
Anticipated loss of major functional domain due to fusion event.DOCK1-PPAPDC1A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DOCK1-PPAPDC1A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DOCK1-PPAPDC1A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
DOCK1-PPAPDC1A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePPAPDC1A

GO:0046839

phospholipid dephosphorylation

17590538


check buttonFusion gene breakpoints across DOCK1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across PPAPDC1A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A04U-01ADOCK1chr10

128788867

+PLPP4chr10

122263330

+
ChimerDB4BRCATCGA-A2-A04U-01ADOCK1chr10

128788867

+PPAPDC1Achr10

122263330

+
ChimerDB4BRCATCGA-A2-A04U-01ADOCK1chr10

128796513

-PPAPDC1Achr10

122263330

+
ChimerDB4BRCATCGA-A2-A04U-01ADOCK1chr10

128796513

+PPAPDC1Achr10

122263330

+
ChimerDB4BRCATCGA-A2-A04UDOCK1chr10

128796513

+PPAPDC1Achr10

122263329

+


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Fusion Gene ORF analysis for DOCK1-PPAPDC1A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000280333ENST00000496437DOCK1chr10

128788867

+PPAPDC1Achr10

122263330

+
5CDS-intronENST00000280333ENST00000496437DOCK1chr10

128796513

+PPAPDC1Achr10

122263330

+
5CDS-intronENST00000280333ENST00000496437DOCK1chr10

128796513

+PPAPDC1Achr10

122263329

+
In-frameENST00000280333ENST00000369073DOCK1chr10

128788867

+PPAPDC1Achr10

122263330

+
In-frameENST00000280333ENST00000369073DOCK1chr10

128796513

+PPAPDC1Achr10

122263330

+
In-frameENST00000280333ENST00000369073DOCK1chr10

128796513

+PPAPDC1Achr10

122263329

+
In-frameENST00000280333ENST00000398248DOCK1chr10

128788867

+PPAPDC1Achr10

122263330

+
In-frameENST00000280333ENST00000398248DOCK1chr10

128796513

+PPAPDC1Achr10

122263330

+
In-frameENST00000280333ENST00000398248DOCK1chr10

128796513

+PPAPDC1Achr10

122263329

+
In-frameENST00000280333ENST00000398250DOCK1chr10

128788867

+PPAPDC1Achr10

122263330

+
In-frameENST00000280333ENST00000398250DOCK1chr10

128796513

+PPAPDC1Achr10

122263330

+
In-frameENST00000280333ENST00000398250DOCK1chr10

128796513

+PPAPDC1Achr10

122263329

+
In-frameENST00000280333ENST00000439221DOCK1chr10

128788867

+PPAPDC1Achr10

122263330

+
In-frameENST00000280333ENST00000439221DOCK1chr10

128796513

+PPAPDC1Achr10

122263330

+
In-frameENST00000280333ENST00000439221DOCK1chr10

128796513

+PPAPDC1Achr10

122263329

+
In-frameENST00000280333ENST00000541332DOCK1chr10

128788867

+PPAPDC1Achr10

122263330

+
In-frameENST00000280333ENST00000541332DOCK1chr10

128796513

+PPAPDC1Achr10

122263330

+
In-frameENST00000280333ENST00000541332DOCK1chr10

128796513

+PPAPDC1Achr10

122263329

+
intron-3CDSENST00000484400ENST00000369073DOCK1chr10

128788867

+PPAPDC1Achr10

122263330

+
intron-3CDSENST00000484400ENST00000369073DOCK1chr10

128796513

+PPAPDC1Achr10

122263330

+
intron-3CDSENST00000484400ENST00000369073DOCK1chr10

128796513

+PPAPDC1Achr10

122263329

+
intron-3CDSENST00000484400ENST00000398248DOCK1chr10

128788867

+PPAPDC1Achr10

122263330

+
intron-3CDSENST00000484400ENST00000398248DOCK1chr10

128796513

+PPAPDC1Achr10

122263330

+
intron-3CDSENST00000484400ENST00000398248DOCK1chr10

128796513

+PPAPDC1Achr10

122263329

+
intron-3CDSENST00000484400ENST00000398250DOCK1chr10

128788867

+PPAPDC1Achr10

122263330

+
intron-3CDSENST00000484400ENST00000398250DOCK1chr10

128796513

+PPAPDC1Achr10

122263330

+
intron-3CDSENST00000484400ENST00000398250DOCK1chr10

128796513

+PPAPDC1Achr10

122263329

+
intron-3CDSENST00000484400ENST00000439221DOCK1chr10

128788867

+PPAPDC1Achr10

122263330

+
intron-3CDSENST00000484400ENST00000439221DOCK1chr10

128796513

+PPAPDC1Achr10

122263330

+
intron-3CDSENST00000484400ENST00000439221DOCK1chr10

128796513

+PPAPDC1Achr10

122263329

+
intron-3CDSENST00000484400ENST00000541332DOCK1chr10

128788867

+PPAPDC1Achr10

122263330

+
intron-3CDSENST00000484400ENST00000541332DOCK1chr10

128796513

+PPAPDC1Achr10

122263330

+
intron-3CDSENST00000484400ENST00000541332DOCK1chr10

128796513

+PPAPDC1Achr10

122263329

+
intron-intronENST00000484400ENST00000496437DOCK1chr10

128788867

+PPAPDC1Achr10

122263330

+
intron-intronENST00000484400ENST00000496437DOCK1chr10

128796513

+PPAPDC1Achr10

122263330

+
intron-intronENST00000484400ENST00000496437DOCK1chr10

128796513

+PPAPDC1Achr10

122263329

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000280333DOCK1chr10128796513+ENST00000398250PPAPDC1Achr10122263329+1989876281635535
ENST00000280333DOCK1chr10128796513+ENST00000439221PPAPDC1Achr10122263329+1800876281446472
ENST00000280333DOCK1chr10128796513+ENST00000398248PPAPDC1Achr10122263329+1538876281110360
ENST00000280333DOCK1chr10128796513+ENST00000541332PPAPDC1Achr10122263329+2185876281521497
ENST00000280333DOCK1chr10128796513+ENST00000369073PPAPDC1Achr10122263329+1985876281635535
ENST00000280333DOCK1chr10128788867+ENST00000398250PPAPDC1Achr10122263330+1695582281341437
ENST00000280333DOCK1chr10128788867+ENST00000439221PPAPDC1Achr10122263330+1506582281152374
ENST00000280333DOCK1chr10128788867+ENST00000398248PPAPDC1Achr10122263330+124458228816262
ENST00000280333DOCK1chr10128788867+ENST00000541332PPAPDC1Achr10122263330+1891582281227399
ENST00000280333DOCK1chr10128788867+ENST00000369073PPAPDC1Achr10122263330+1691582281341437
ENST00000280333DOCK1chr10128796513+ENST00000398250PPAPDC1Achr10122263330+1989876281635535
ENST00000280333DOCK1chr10128796513+ENST00000439221PPAPDC1Achr10122263330+1800876281446472
ENST00000280333DOCK1chr10128796513+ENST00000398248PPAPDC1Achr10122263330+1538876281110360
ENST00000280333DOCK1chr10128796513+ENST00000541332PPAPDC1Achr10122263330+2185876281521497
ENST00000280333DOCK1chr10128796513+ENST00000369073PPAPDC1Achr10122263330+1985876281635535

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000280333ENST00000398250DOCK1chr10128796513+PPAPDC1Achr10122263329+0.0008795650.9991204
ENST00000280333ENST00000439221DOCK1chr10128796513+PPAPDC1Achr10122263329+0.000859580.9991404
ENST00000280333ENST00000398248DOCK1chr10128796513+PPAPDC1Achr10122263329+0.0004794250.99952054
ENST00000280333ENST00000541332DOCK1chr10128796513+PPAPDC1Achr10122263329+0.00206130.9979387
ENST00000280333ENST00000369073DOCK1chr10128796513+PPAPDC1Achr10122263329+0.0009066560.9990934
ENST00000280333ENST00000398250DOCK1chr10128788867+PPAPDC1Achr10122263330+0.0011857160.99881434
ENST00000280333ENST00000439221DOCK1chr10128788867+PPAPDC1Achr10122263330+0.0005724120.9994276
ENST00000280333ENST00000398248DOCK1chr10128788867+PPAPDC1Achr10122263330+0.0008180370.9991819
ENST00000280333ENST00000541332DOCK1chr10128788867+PPAPDC1Achr10122263330+0.0063120260.99368805
ENST00000280333ENST00000369073DOCK1chr10128788867+PPAPDC1Achr10122263330+0.001236490.99876356
ENST00000280333ENST00000398250DOCK1chr10128796513+PPAPDC1Achr10122263330+0.0008795650.9991204
ENST00000280333ENST00000439221DOCK1chr10128796513+PPAPDC1Achr10122263330+0.000859580.9991404
ENST00000280333ENST00000398248DOCK1chr10128796513+PPAPDC1Achr10122263330+0.0004794250.99952054
ENST00000280333ENST00000541332DOCK1chr10128796513+PPAPDC1Achr10122263330+0.00206130.9979387
ENST00000280333ENST00000369073DOCK1chr10128796513+PPAPDC1Achr10122263330+0.0009066560.9990934

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Fusion Genomic Features for DOCK1-PPAPDC1A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DOCK1chr10128796513+PPAPDC1Achr10122263329+0.002085780.99791425
DOCK1chr10128796513+PPAPDC1Achr10122263329+0.002085780.99791425
DOCK1chr10128788867+PPAPDC1Achr10122263329+1.16E-050.99998844
DOCK1chr10128796513+PPAPDC1Achr10122263329+0.002085780.99791425
DOCK1chr10128796513+PPAPDC1Achr10122263329+0.002085780.99791425
DOCK1chr10128788867+PPAPDC1Achr10122263329+1.16E-050.99998844

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for DOCK1-PPAPDC1A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:128796513/chr10:122263330)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DOCK1

Q14185

.
FUNCTION: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829). Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed:8657152). {ECO:0000269|PubMed:19004829, ECO:0000269|PubMed:8657152}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDOCK1chr10:128788867chr10:122263330ENST00000280333+6529_701571866.0DomainSH3
HgeneDOCK1chr10:128796513chr10:122263329ENST00000280333+8529_702551866.0DomainSH3
HgeneDOCK1chr10:128796513chr10:122263330ENST00000280333+8529_702551866.0DomainSH3
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000039824803102_1101897.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000039824803143_1461897.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000039824803195_2051897.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000039825007102_11018272.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000039825007143_14618272.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000039825007195_20518272.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000043922105102_11018209.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000043922105143_14618209.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000043922105195_20518209.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000039824803102_1101897.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000039824803143_1461897.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000039824803195_2051897.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000039825007102_11018272.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000039825007143_14618272.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000039825007195_20518272.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000043922105102_11018209.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000043922105143_14618209.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000043922105195_20518209.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000039824803102_1101897.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000039824803143_1461897.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000039824803195_2051897.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000039825007102_11018272.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000039825007143_14618272.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000039825007195_20518272.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000043922105102_11018209.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000043922105143_14618209.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000043922105195_20518209.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000039824803142_1621897.0TransmembraneHelical
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000039824803179_1991897.0TransmembraneHelical
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000039824803202_2221897.0TransmembraneHelical
TgenePPAPDC1Achr10:128788867chr10:122263330ENST000003982480349_691897.0TransmembraneHelical
TgenePPAPDC1Achr10:128788867chr10:122263330ENST000003982480384_1041897.0TransmembraneHelical
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000039825007142_16218272.0TransmembraneHelical
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000039825007179_19918272.0TransmembraneHelical
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000039825007202_22218272.0TransmembraneHelical
TgenePPAPDC1Achr10:128788867chr10:122263330ENST000003982500749_6918272.0TransmembraneHelical
TgenePPAPDC1Achr10:128788867chr10:122263330ENST000003982500784_10418272.0TransmembraneHelical
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000043922105142_16218209.0TransmembraneHelical
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000043922105179_19918209.0TransmembraneHelical
TgenePPAPDC1Achr10:128788867chr10:122263330ENST0000043922105202_22218209.0TransmembraneHelical
TgenePPAPDC1Achr10:128788867chr10:122263330ENST000004392210549_6918209.0TransmembraneHelical
TgenePPAPDC1Achr10:128788867chr10:122263330ENST000004392210584_10418209.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000039824803142_1621897.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000039824803179_1991897.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000039824803202_2221897.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST000003982480349_691897.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST000003982480384_1041897.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000039825007142_16218272.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000039825007179_19918272.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000039825007202_22218272.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST000003982500749_6918272.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST000003982500784_10418272.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000043922105142_16218209.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000043922105179_19918209.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST0000043922105202_22218209.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST000004392210549_6918209.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST000004392210584_10418209.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000039824803142_1621897.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000039824803179_1991897.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000039824803202_2221897.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST000003982480349_691897.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST000003982480384_1041897.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000039825007142_16218272.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000039825007179_19918272.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000039825007202_22218272.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST000003982500749_6918272.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST000003982500784_10418272.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000043922105142_16218209.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000043922105179_19918209.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST0000043922105202_22218209.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST000004392210549_6918209.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST000004392210584_10418209.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDOCK1chr10:128788867chr10:122263330ENST00000280333+6521207_16171571866.0DomainDOCKER
HgeneDOCK1chr10:128788867chr10:122263330ENST00000280333+652425_6091571866.0DomainC2 DOCK-type
HgeneDOCK1chr10:128796513chr10:122263329ENST00000280333+8521207_16172551866.0DomainDOCKER
HgeneDOCK1chr10:128796513chr10:122263329ENST00000280333+852425_6092551866.0DomainC2 DOCK-type
HgeneDOCK1chr10:128796513chr10:122263330ENST00000280333+8521207_16172551866.0DomainDOCKER
HgeneDOCK1chr10:128796513chr10:122263330ENST00000280333+852425_6092551866.0DomainC2 DOCK-type
HgeneDOCK1chr10:128788867chr10:122263330ENST00000280333+6521687_16951571866.0RegionPhosphoinositide-binding
HgeneDOCK1chr10:128796513chr10:122263329ENST00000280333+8521687_16952551866.0RegionPhosphoinositide-binding
HgeneDOCK1chr10:128796513chr10:122263330ENST00000280333+8521687_16952551866.0RegionPhosphoinositide-binding
TgenePPAPDC1Achr10:128788867chr10:122263330ENST00000398248034_241897.0TransmembraneHelical
TgenePPAPDC1Achr10:128788867chr10:122263330ENST00000398250074_2418272.0TransmembraneHelical
TgenePPAPDC1Achr10:128788867chr10:122263330ENST00000439221054_2418209.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST00000398248034_241897.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST00000398250074_2418272.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263329ENST00000439221054_2418209.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST00000398248034_241897.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST00000398250074_2418272.0TransmembraneHelical
TgenePPAPDC1Achr10:128796513chr10:122263330ENST00000439221054_2418209.0TransmembraneHelical


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Fusion Gene Sequence for DOCK1-PPAPDC1A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>23770_23770_1_DOCK1-PPAPDC1A_DOCK1_chr10_128788867_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000369073_length(transcript)=1691nt_BP=582nt
CTCCGCCGCAAACTTTTTCCTCCCCATCCTGTCGCGGCTCGAAAGGAATGGAAAATGGCGGCCTAGACGCGGAGTTTCCTGCCCGACCCG
CGGCGGCTCCGGCGGCGCCATGACGCGCTGGGTGCCCACCAAGCGCGAGGAGAAGTACGGCGTGGCTTTTTATAACTATGATGCCAGAGG
AGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGGGTGGTACCGAGGTTACACGTTACGAAAAAA
GTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGGAAAAGGGCAACATGAAACAGTCATCCCGGG
TGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAGGCAGCTCTACGTGCAAGATAACAGGGAGAT
GTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGA
ACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGTCATCCAGCCAGAAGA
GATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAATTTCTTTCCTCACACCCCTGGCTGT
TATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGTGTCCTTGGCTCTTGCTTTGAATGG
AGTCTGCACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTTTCCAGATGGAGTGATGAACTCGGA
AATGCATTGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTCCTCCTTTGCCTTTTCGGGCCTTGG
CTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTGTGCTGCCATCCTGCC
CTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTCCTTTGTGGGTGGAGTCATCGGCCT
CATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAGTCTGCGAGTCCCAGC
CTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCCGGTATGACCAGTGTC
CTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTAGTGTATTTTTCATCA
GTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCCAACATCCTTGAATTT
GCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGATTCGTCTATCTGAAAT
GTTTGCTGTAACAGCCACCTTCCTATGTTTTCATGGTTGTAAAACATAATAAAACCTCCCACGTGGAAGAC

>23770_23770_1_DOCK1-PPAPDC1A_DOCK1_chr10_128788867_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000369073_length(amino acids)=437AA_BP=184
MSRLERNGKWRPRRGVSCPTRGGSGGAMTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPAS
YIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKI
DYGNSFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGVCTNTIKLI
VGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIAL
SRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVSLRVPASLKKEERPTADSAPSLPLEGITEGPV

--------------------------------------------------------------
>23770_23770_2_DOCK1-PPAPDC1A_DOCK1_chr10_128788867_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000398248_length(transcript)=1244nt_BP=582nt
CTCCGCCGCAAACTTTTTCCTCCCCATCCTGTCGCGGCTCGAAAGGAATGGAAAATGGCGGCCTAGACGCGGAGTTTCCTGCCCGACCCG
CGGCGGCTCCGGCGGCGCCATGACGCGCTGGGTGCCCACCAAGCGCGAGGAGAAGTACGGCGTGGCTTTTTATAACTATGATGCCAGAGG
AGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGGGTGGTACCGAGGTTACACGTTACGAAAAAA
GTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGGAAAAGGGCAACATGAAACAGTCATCCCGGG
TGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAGGCAGCTCTACGTGCAAGATAACAGGGAGAT
GTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGA
ACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGTCATCCAGCCAGAAGA
GATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTATTCCTTTGTGGGTGGAGTCATCGGCCTC
ATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAGTCTGCGAGTCCCAGCC
TCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCCGGTATGACCAGTGTCC
TGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTAGTGTATTTTTCATCAG
TTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCCAACATCCTTGAATTTG
CAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGATTCGTCTATCTGAAATG
TTTGCTGTAACAGCCACCTTCCTATGTTTTCATGGTTGTAAAACATAATAAAACCTCCCACGTGGAAGACTTGG

>23770_23770_2_DOCK1-PPAPDC1A_DOCK1_chr10_128788867_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000398248_length(amino acids)=262AA_BP=184
MSRLERNGKWRPRRGVSCPTRGGSGGAMTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPAS
YIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKI
DYGNSFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFIPLWVESSASFLHTFATDSTILLWPTQLAINPTLVCESQPH

--------------------------------------------------------------
>23770_23770_3_DOCK1-PPAPDC1A_DOCK1_chr10_128788867_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000398250_length(transcript)=1695nt_BP=582nt
CTCCGCCGCAAACTTTTTCCTCCCCATCCTGTCGCGGCTCGAAAGGAATGGAAAATGGCGGCCTAGACGCGGAGTTTCCTGCCCGACCCG
CGGCGGCTCCGGCGGCGCCATGACGCGCTGGGTGCCCACCAAGCGCGAGGAGAAGTACGGCGTGGCTTTTTATAACTATGATGCCAGAGG
AGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGGGTGGTACCGAGGTTACACGTTACGAAAAAA
GTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGGAAAAGGGCAACATGAAACAGTCATCCCGGG
TGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAGGCAGCTCTACGTGCAAGATAACAGGGAGAT
GTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGA
ACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGTCATCCAGCCAGAAGA
GATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAATTTCTTTCCTCACACCCCTGGCTGT
TATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGTGTCCTTGGCTCTTGCTTTGAATGG
AGTCTGCACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTTTCCAGATGGAGTGATGAACTCGGA
AATGCATTGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTCCTCCTTTGCCTTTTCGGGCCTTGG
CTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTGTGCTGCCATCCTGCC
CTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTCCTTTGTGGGTGGAGTCATCGGCCT
CATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAGTCTGCGAGTCCCAGC
CTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCCGGTATGACCAGTGTC
CTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTAGTGTATTTTTCATCA
GTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCCAACATCCTTGAATTT
GCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGATTCGTCTATCTGAAAT
GTTTGCTGTAACAGCCACCTTCCTATGTTTTCATGGTTGTAAAACATAATAAAACCTCCCACGTGGAAGACTTGG

>23770_23770_3_DOCK1-PPAPDC1A_DOCK1_chr10_128788867_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000398250_length(amino acids)=437AA_BP=184
MSRLERNGKWRPRRGVSCPTRGGSGGAMTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPAS
YIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKI
DYGNSFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGVCTNTIKLI
VGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIAL
SRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVSLRVPASLKKEERPTADSAPSLPLEGITEGPV

--------------------------------------------------------------
>23770_23770_4_DOCK1-PPAPDC1A_DOCK1_chr10_128788867_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000439221_length(transcript)=1506nt_BP=582nt
CTCCGCCGCAAACTTTTTCCTCCCCATCCTGTCGCGGCTCGAAAGGAATGGAAAATGGCGGCCTAGACGCGGAGTTTCCTGCCCGACCCG
CGGCGGCTCCGGCGGCGCCATGACGCGCTGGGTGCCCACCAAGCGCGAGGAGAAGTACGGCGTGGCTTTTTATAACTATGATGCCAGAGG
AGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGGGTGGTACCGAGGTTACACGTTACGAAAAAA
GTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGGAAAAGGGCAACATGAAACAGTCATCCCGGG
TGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAGGCAGCTCTACGTGCAAGATAACAGGGAGAT
GTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGA
ACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGTCATCCAGCCAGAAGA
GATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAATTTCTTTCCTCACACCCCTGGCTGT
TATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGTTGCCTTTTCGGGCCTTGGCTTCACGAC
GTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTGTGCTGCCATCCTGCCCTTGTACTG
CGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTCCTTTGTGGGTGGAGTCATCGGCCTCATTTTTGC
ATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAGTCTGCGAGTCCCAGCCTCACTGAA
GAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCCGGTATGACCAGTGTCCTGGGAGGA
TGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTAGTGTATTTTTCATCAGTTGTTTCT
CAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCCAACATCCTTGAATTTGCAAGTGAA
GGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGATTCGTCTATCTGAAATGTTTGCTGT
AACAGCCACCTTCCTATGTTTTCATGGTTGTAAAACATAATAAAACCTCCCACGTGGAAGACTTGG

>23770_23770_4_DOCK1-PPAPDC1A_DOCK1_chr10_128788867_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000439221_length(amino acids)=374AA_BP=184
MSRLERNGKWRPRRGVSCPTRGGSGGAMTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPAS
YIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKI
DYGNSFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLVAFSGLGFTTFYLAGKLHC
FTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVSLRVPASLKKEERPTADS
APSLPLEGITEGPV

--------------------------------------------------------------
>23770_23770_5_DOCK1-PPAPDC1A_DOCK1_chr10_128788867_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000541332_length(transcript)=1891nt_BP=582nt
CTCCGCCGCAAACTTTTTCCTCCCCATCCTGTCGCGGCTCGAAAGGAATGGAAAATGGCGGCCTAGACGCGGAGTTTCCTGCCCGACCCG
CGGCGGCTCCGGCGGCGCCATGACGCGCTGGGTGCCCACCAAGCGCGAGGAGAAGTACGGCGTGGCTTTTTATAACTATGATGCCAGAGG
AGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGGGTGGTACCGAGGTTACACGTTACGAAAAAA
GTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGGAAAAGGGCAACATGAAACAGTCATCCCGGG
TGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAGGCAGCTCTACGTGCAAGATAACAGGGAGAT
GTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGA
ACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGTCATCCAGCCAGAAGA
GATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAATTTCTTTCCTCACACCCCTGGCTGT
TATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGTGTCCTTGGCTCTTGCTTTGAATGG
AGTCTGCACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTTTCCAGATGGAGTGATGAACTCGGA
AATGCATTGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTCCTCCTTTGCCTTTTCGGGCCTTGG
CTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTGTGCTGCCATCCTGCC
CTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGTTGGCTGCTGTGTATGGCAGGGCCCACA
GTCACATTTACCATCGGCTGCCAACCCCCGCCTCTGTCTGGGAACCTCTGAACCTTGACTGCCCATCTAAGTCCACCCGCCTCTGTGTTG
GTGCCTAGGAGAGCGTAAGAAGCCTCAGCCCCTGGCTCACCCCTCCCTCCGGTCAAAGTCCACTGCATATCCTGCTTTCAGCCTCAAGAG
AGGCATTCTCAGTCAGGACTTCTGCCCTCTTCCTGCCTCCAGGATAGCCCTGGTGTTTCCCCGTGATGTAATTCCCAGGGAAGATGGACG
TTGATTGCTCCCAAGTCTCACTGGCATCCTTCCTTTGTTTTACTCAAGGGAACCTGTCTCTTCTCAGCTTTCTGTGGTGTTCTGTGGTTC
CTCCTGCTCAGCATATTTATAGACTCCAACTTTTCCTTCCCACTCTGGTCTAGTGATCCTCAGTTGTTGCCTGAATCATTGCAGAAGCCT
CTCAGCCTGGCTCCCTCCTTCCTTCTTTGGCCCTCAACTGCATTTGGAATGTGCCTTTAGAGCCTGCGTTAGCACATGTCACTTTTGCAA
AAATCCTCCAGTGATTCTCATTTCACTCAGCATCACAGCCTGTGTCCTGCCATGGTCCATAAGATCTGCTCCCTCCGTACTTCTTTGATG
CTATGTTCAAGCTACTTGTCCTCCTCGTTCACATGATTGCATCGCTTGAGCTTCTTGCTACTCCTTGAACAGGCCCGTCCCATCCCACCT
C

>23770_23770_5_DOCK1-PPAPDC1A_DOCK1_chr10_128788867_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000541332_length(amino acids)=399AA_BP=184
MSRLERNGKWRPRRGVSCPTRGGSGGAMTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPAS
YIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKI
DYGNSFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGVCTNTIKLI
VGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIAL
SRMCDYKHHWQVGCCVWQGPQSHLPSAANPRLCLGTSEP

--------------------------------------------------------------
>23770_23770_6_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263329_ENST00000369073_length(transcript)=1985nt_BP=876nt
CTCCGCCGCAAACTTTTTCCTCCCCATCCTGTCGCGGCTCGAAAGGAATGGAAAATGGCGGCCTAGACGCGGAGTTTCCTGCCCGACCCG
CGGCGGCTCCGGCGGCGCCATGACGCGCTGGGTGCCCACCAAGCGCGAGGAGAAGTACGGCGTGGCTTTTTATAACTATGATGCCAGAGG
AGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGGGTGGTACCGAGGTTACACGTTACGAAAAAA
GTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGGAAAAGGGCAACATGAAACAGTCATCCCGGG
TGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAGGCAGCTCTACGTGCAAGATAACAGGGAGAT
GTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGA
ACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGAATTCTAGATTTGGACCTGGTGGTTAGAGATGAAGATGGGAATATTTT
GGATCCAGAATTAACTAGCACGATTAGTCTCTTCAGAGCTCATGAAATAGCTTCTAAACAAGTGGAGGAAAGGTTACAAGAGGAAAAATC
TCAAAAGCAGAACATAGATATTAACAGACAAGCCAAGTTTGCTGCAACCCCTTCTCTGGCCTTGTTTGTGAACCTCAAAAATGTGGTTTG
TAAAATAGGAGAAGATGCTGAAGTCCTCATGTCTCTATATGACCCTGTGGAGTCCAAATTCATCAGTTTTACAGAGTTTTTGGATCCGTT
CCAGAGAGTCATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAAT
TTCTTTCCTCACACCCCTGGCTGTTATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGT
GTCCTTGGCTCTTGCTTTGAATGGAGTCTGCACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTT
TCCAGATGGAGTGATGAACTCGGAAATGCATTGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTC
CTCCTTTGCCTTTTCGGGCCTTGGCTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTG
GCGGCTCTGTGCTGCCATCCTGCCCTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTC
CTTTGTGGGTGGAGTCATCGGCCTCATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACC
CTACGTTAGTCTGCGAGTCCCAGCCTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCAC
CGAAGGCCCGGTATGACCAGTGTCCTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGG
TTTTCTGTAGTGTATTTTTCATCAGTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATG
TCTACTTCCAACATCCTTGAATTTGCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGC
TTGGCCGATTCGTCTATCTGAAATGTTTGCTGTAACAGCCACCTTCCTATGTTTTCATGGTTGTAAAACATAATAAAACCTCCCACGTGG
AAGAC

>23770_23770_6_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263329_ENST00000369073_length(amino acids)=535AA_BP=282
MSRLERNGKWRPRRGVSCPTRGGSGGAMTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPAS
YIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKI
DYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVL
MSLYDPVESKFISFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGV
CTNTIKLIVGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPL
YCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVSLRVPASLKKEERPTADSAPSLPLEGITEGPV

--------------------------------------------------------------
>23770_23770_7_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263329_ENST00000398248_length(transcript)=1538nt_BP=876nt
CTCCGCCGCAAACTTTTTCCTCCCCATCCTGTCGCGGCTCGAAAGGAATGGAAAATGGCGGCCTAGACGCGGAGTTTCCTGCCCGACCCG
CGGCGGCTCCGGCGGCGCCATGACGCGCTGGGTGCCCACCAAGCGCGAGGAGAAGTACGGCGTGGCTTTTTATAACTATGATGCCAGAGG
AGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGGGTGGTACCGAGGTTACACGTTACGAAAAAA
GTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGGAAAAGGGCAACATGAAACAGTCATCCCGGG
TGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAGGCAGCTCTACGTGCAAGATAACAGGGAGAT
GTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGA
ACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGAATTCTAGATTTGGACCTGGTGGTTAGAGATGAAGATGGGAATATTTT
GGATCCAGAATTAACTAGCACGATTAGTCTCTTCAGAGCTCATGAAATAGCTTCTAAACAAGTGGAGGAAAGGTTACAAGAGGAAAAATC
TCAAAAGCAGAACATAGATATTAACAGACAAGCCAAGTTTGCTGCAACCCCTTCTCTGGCCTTGTTTGTGAACCTCAAAAATGTGGTTTG
TAAAATAGGAGAAGATGCTGAAGTCCTCATGTCTCTATATGACCCTGTGGAGTCCAAATTCATCAGTTTTACAGAGTTTTTGGATCCGTT
CCAGAGAGTCATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTATTCC
TTTGTGGGTGGAGTCATCGGCCTCATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCC
TACGTTAGTCTGCGAGTCCCAGCCTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACC
GAAGGCCCGGTATGACCAGTGTCCTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGT
TTTCTGTAGTGTATTTTTCATCAGTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGT
CTACTTCCAACATCCTTGAATTTGCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCT
TGGCCGATTCGTCTATCTGAAATGTTTGCTGTAACAGCCACCTTCCTATGTTTTCATGGTTGTAAAACATAATAAAACCTCCCACGTGGA
AGACTTGG

>23770_23770_7_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263329_ENST00000398248_length(amino acids)=360AA_BP=282
MSRLERNGKWRPRRGVSCPTRGGSGGAMTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPAS
YIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKI
DYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVL
MSLYDPVESKFISFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFIPLWVESSASFLHTFATDSTILLWPTQLAINPTLVCESQPH


--------------------------------------------------------------
>23770_23770_8_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263329_ENST00000398250_length(transcript)=1989nt_BP=876nt
CTCCGCCGCAAACTTTTTCCTCCCCATCCTGTCGCGGCTCGAAAGGAATGGAAAATGGCGGCCTAGACGCGGAGTTTCCTGCCCGACCCG
CGGCGGCTCCGGCGGCGCCATGACGCGCTGGGTGCCCACCAAGCGCGAGGAGAAGTACGGCGTGGCTTTTTATAACTATGATGCCAGAGG
AGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGGGTGGTACCGAGGTTACACGTTACGAAAAAA
GTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGGAAAAGGGCAACATGAAACAGTCATCCCGGG
TGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAGGCAGCTCTACGTGCAAGATAACAGGGAGAT
GTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGA
ACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGAATTCTAGATTTGGACCTGGTGGTTAGAGATGAAGATGGGAATATTTT
GGATCCAGAATTAACTAGCACGATTAGTCTCTTCAGAGCTCATGAAATAGCTTCTAAACAAGTGGAGGAAAGGTTACAAGAGGAAAAATC
TCAAAAGCAGAACATAGATATTAACAGACAAGCCAAGTTTGCTGCAACCCCTTCTCTGGCCTTGTTTGTGAACCTCAAAAATGTGGTTTG
TAAAATAGGAGAAGATGCTGAAGTCCTCATGTCTCTATATGACCCTGTGGAGTCCAAATTCATCAGTTTTACAGAGTTTTTGGATCCGTT
CCAGAGAGTCATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAAT
TTCTTTCCTCACACCCCTGGCTGTTATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGT
GTCCTTGGCTCTTGCTTTGAATGGAGTCTGCACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTT
TCCAGATGGAGTGATGAACTCGGAAATGCATTGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTC
CTCCTTTGCCTTTTCGGGCCTTGGCTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTG
GCGGCTCTGTGCTGCCATCCTGCCCTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTC
CTTTGTGGGTGGAGTCATCGGCCTCATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACC
CTACGTTAGTCTGCGAGTCCCAGCCTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCAC
CGAAGGCCCGGTATGACCAGTGTCCTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGG
TTTTCTGTAGTGTATTTTTCATCAGTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATG
TCTACTTCCAACATCCTTGAATTTGCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGC
TTGGCCGATTCGTCTATCTGAAATGTTTGCTGTAACAGCCACCTTCCTATGTTTTCATGGTTGTAAAACATAATAAAACCTCCCACGTGG
AAGACTTGG

>23770_23770_8_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263329_ENST00000398250_length(amino acids)=535AA_BP=282
MSRLERNGKWRPRRGVSCPTRGGSGGAMTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPAS
YIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKI
DYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVL
MSLYDPVESKFISFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGV
CTNTIKLIVGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPL
YCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVSLRVPASLKKEERPTADSAPSLPLEGITEGPV

--------------------------------------------------------------
>23770_23770_9_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263329_ENST00000439221_length(transcript)=1800nt_BP=876nt
CTCCGCCGCAAACTTTTTCCTCCCCATCCTGTCGCGGCTCGAAAGGAATGGAAAATGGCGGCCTAGACGCGGAGTTTCCTGCCCGACCCG
CGGCGGCTCCGGCGGCGCCATGACGCGCTGGGTGCCCACCAAGCGCGAGGAGAAGTACGGCGTGGCTTTTTATAACTATGATGCCAGAGG
AGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGGGTGGTACCGAGGTTACACGTTACGAAAAAA
GTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGGAAAAGGGCAACATGAAACAGTCATCCCGGG
TGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAGGCAGCTCTACGTGCAAGATAACAGGGAGAT
GTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGA
ACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGAATTCTAGATTTGGACCTGGTGGTTAGAGATGAAGATGGGAATATTTT
GGATCCAGAATTAACTAGCACGATTAGTCTCTTCAGAGCTCATGAAATAGCTTCTAAACAAGTGGAGGAAAGGTTACAAGAGGAAAAATC
TCAAAAGCAGAACATAGATATTAACAGACAAGCCAAGTTTGCTGCAACCCCTTCTCTGGCCTTGTTTGTGAACCTCAAAAATGTGGTTTG
TAAAATAGGAGAAGATGCTGAAGTCCTCATGTCTCTATATGACCCTGTGGAGTCCAAATTCATCAGTTTTACAGAGTTTTTGGATCCGTT
CCAGAGAGTCATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAAT
TTCTTTCCTCACACCCCTGGCTGTTATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGTTGC
CTTTTCGGGCCTTGGCTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTG
TGCTGCCATCCTGCCCTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTCCTTTGTGGG
TGGAGTCATCGGCCTCATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAG
TCTGCGAGTCCCAGCCTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCC
GGTATGACCAGTGTCCTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTA
GTGTATTTTTCATCAGTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCC
AACATCCTTGAATTTGCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGAT
TCGTCTATCTGAAATGTTTGCTGTAACAGCCACCTTCCTATGTTTTCATGGTTGTAAAACATAATAAAACCTCCCACGTGGAAGACTTGG


>23770_23770_9_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263329_ENST00000439221_length(amino acids)=472AA_BP=282
MSRLERNGKWRPRRGVSCPTRGGSGGAMTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPAS
YIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKI
DYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVL
MSLYDPVESKFISFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLVAFSGLGFTTF
YLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVSLRVPASLKK
EERPTADSAPSLPLEGITEGPV

--------------------------------------------------------------
>23770_23770_10_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263329_ENST00000541332_length(transcript)=2185nt_BP=876nt
CTCCGCCGCAAACTTTTTCCTCCCCATCCTGTCGCGGCTCGAAAGGAATGGAAAATGGCGGCCTAGACGCGGAGTTTCCTGCCCGACCCG
CGGCGGCTCCGGCGGCGCCATGACGCGCTGGGTGCCCACCAAGCGCGAGGAGAAGTACGGCGTGGCTTTTTATAACTATGATGCCAGAGG
AGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGGGTGGTACCGAGGTTACACGTTACGAAAAAA
GTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGGAAAAGGGCAACATGAAACAGTCATCCCGGG
TGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAGGCAGCTCTACGTGCAAGATAACAGGGAGAT
GTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGA
ACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGAATTCTAGATTTGGACCTGGTGGTTAGAGATGAAGATGGGAATATTTT
GGATCCAGAATTAACTAGCACGATTAGTCTCTTCAGAGCTCATGAAATAGCTTCTAAACAAGTGGAGGAAAGGTTACAAGAGGAAAAATC
TCAAAAGCAGAACATAGATATTAACAGACAAGCCAAGTTTGCTGCAACCCCTTCTCTGGCCTTGTTTGTGAACCTCAAAAATGTGGTTTG
TAAAATAGGAGAAGATGCTGAAGTCCTCATGTCTCTATATGACCCTGTGGAGTCCAAATTCATCAGTTTTACAGAGTTTTTGGATCCGTT
CCAGAGAGTCATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAAT
TTCTTTCCTCACACCCCTGGCTGTTATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGT
GTCCTTGGCTCTTGCTTTGAATGGAGTCTGCACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTT
TCCAGATGGAGTGATGAACTCGGAAATGCATTGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTC
CTCCTTTGCCTTTTCGGGCCTTGGCTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTG
GCGGCTCTGTGCTGCCATCCTGCCCTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGTTGG
CTGCTGTGTATGGCAGGGCCCACAGTCACATTTACCATCGGCTGCCAACCCCCGCCTCTGTCTGGGAACCTCTGAACCTTGACTGCCCAT
CTAAGTCCACCCGCCTCTGTGTTGGTGCCTAGGAGAGCGTAAGAAGCCTCAGCCCCTGGCTCACCCCTCCCTCCGGTCAAAGTCCACTGC
ATATCCTGCTTTCAGCCTCAAGAGAGGCATTCTCAGTCAGGACTTCTGCCCTCTTCCTGCCTCCAGGATAGCCCTGGTGTTTCCCCGTGA
TGTAATTCCCAGGGAAGATGGACGTTGATTGCTCCCAAGTCTCACTGGCATCCTTCCTTTGTTTTACTCAAGGGAACCTGTCTCTTCTCA
GCTTTCTGTGGTGTTCTGTGGTTCCTCCTGCTCAGCATATTTATAGACTCCAACTTTTCCTTCCCACTCTGGTCTAGTGATCCTCAGTTG
TTGCCTGAATCATTGCAGAAGCCTCTCAGCCTGGCTCCCTCCTTCCTTCTTTGGCCCTCAACTGCATTTGGAATGTGCCTTTAGAGCCTG
CGTTAGCACATGTCACTTTTGCAAAAATCCTCCAGTGATTCTCATTTCACTCAGCATCACAGCCTGTGTCCTGCCATGGTCCATAAGATC
TGCTCCCTCCGTACTTCTTTGATGCTATGTTCAAGCTACTTGTCCTCCTCGTTCACATGATTGCATCGCTTGAGCTTCTTGCTACTCCTT
GAACAGGCCCGTCCCATCCCACCTC

>23770_23770_10_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263329_ENST00000541332_length(amino acids)=497AA_BP=282
MSRLERNGKWRPRRGVSCPTRGGSGGAMTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPAS
YIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKI
DYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVL
MSLYDPVESKFISFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGV
CTNTIKLIVGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPL
YCAMMIALSRMCDYKHHWQVGCCVWQGPQSHLPSAANPRLCLGTSEP

--------------------------------------------------------------
>23770_23770_11_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000369073_length(transcript)=1985nt_BP=876nt
CTCCGCCGCAAACTTTTTCCTCCCCATCCTGTCGCGGCTCGAAAGGAATGGAAAATGGCGGCCTAGACGCGGAGTTTCCTGCCCGACCCG
CGGCGGCTCCGGCGGCGCCATGACGCGCTGGGTGCCCACCAAGCGCGAGGAGAAGTACGGCGTGGCTTTTTATAACTATGATGCCAGAGG
AGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGGGTGGTACCGAGGTTACACGTTACGAAAAAA
GTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGGAAAAGGGCAACATGAAACAGTCATCCCGGG
TGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAGGCAGCTCTACGTGCAAGATAACAGGGAGAT
GTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGA
ACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGAATTCTAGATTTGGACCTGGTGGTTAGAGATGAAGATGGGAATATTTT
GGATCCAGAATTAACTAGCACGATTAGTCTCTTCAGAGCTCATGAAATAGCTTCTAAACAAGTGGAGGAAAGGTTACAAGAGGAAAAATC
TCAAAAGCAGAACATAGATATTAACAGACAAGCCAAGTTTGCTGCAACCCCTTCTCTGGCCTTGTTTGTGAACCTCAAAAATGTGGTTTG
TAAAATAGGAGAAGATGCTGAAGTCCTCATGTCTCTATATGACCCTGTGGAGTCCAAATTCATCAGTTTTACAGAGTTTTTGGATCCGTT
CCAGAGAGTCATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAAT
TTCTTTCCTCACACCCCTGGCTGTTATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGT
GTCCTTGGCTCTTGCTTTGAATGGAGTCTGCACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTT
TCCAGATGGAGTGATGAACTCGGAAATGCATTGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTC
CTCCTTTGCCTTTTCGGGCCTTGGCTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTG
GCGGCTCTGTGCTGCCATCCTGCCCTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTC
CTTTGTGGGTGGAGTCATCGGCCTCATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACC
CTACGTTAGTCTGCGAGTCCCAGCCTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCAC
CGAAGGCCCGGTATGACCAGTGTCCTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGG
TTTTCTGTAGTGTATTTTTCATCAGTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATG
TCTACTTCCAACATCCTTGAATTTGCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGC
TTGGCCGATTCGTCTATCTGAAATGTTTGCTGTAACAGCCACCTTCCTATGTTTTCATGGTTGTAAAACATAATAAAACCTCCCACGTGG
AAGAC

>23770_23770_11_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000369073_length(amino acids)=535AA_BP=282
MSRLERNGKWRPRRGVSCPTRGGSGGAMTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPAS
YIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKI
DYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVL
MSLYDPVESKFISFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGV
CTNTIKLIVGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPL
YCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVSLRVPASLKKEERPTADSAPSLPLEGITEGPV

--------------------------------------------------------------
>23770_23770_12_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000398248_length(transcript)=1538nt_BP=876nt
CTCCGCCGCAAACTTTTTCCTCCCCATCCTGTCGCGGCTCGAAAGGAATGGAAAATGGCGGCCTAGACGCGGAGTTTCCTGCCCGACCCG
CGGCGGCTCCGGCGGCGCCATGACGCGCTGGGTGCCCACCAAGCGCGAGGAGAAGTACGGCGTGGCTTTTTATAACTATGATGCCAGAGG
AGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGGGTGGTACCGAGGTTACACGTTACGAAAAAA
GTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGGAAAAGGGCAACATGAAACAGTCATCCCGGG
TGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAGGCAGCTCTACGTGCAAGATAACAGGGAGAT
GTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGA
ACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGAATTCTAGATTTGGACCTGGTGGTTAGAGATGAAGATGGGAATATTTT
GGATCCAGAATTAACTAGCACGATTAGTCTCTTCAGAGCTCATGAAATAGCTTCTAAACAAGTGGAGGAAAGGTTACAAGAGGAAAAATC
TCAAAAGCAGAACATAGATATTAACAGACAAGCCAAGTTTGCTGCAACCCCTTCTCTGGCCTTGTTTGTGAACCTCAAAAATGTGGTTTG
TAAAATAGGAGAAGATGCTGAAGTCCTCATGTCTCTATATGACCCTGTGGAGTCCAAATTCATCAGTTTTACAGAGTTTTTGGATCCGTT
CCAGAGAGTCATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTATTCC
TTTGTGGGTGGAGTCATCGGCCTCATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCC
TACGTTAGTCTGCGAGTCCCAGCCTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACC
GAAGGCCCGGTATGACCAGTGTCCTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGT
TTTCTGTAGTGTATTTTTCATCAGTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGT
CTACTTCCAACATCCTTGAATTTGCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCT
TGGCCGATTCGTCTATCTGAAATGTTTGCTGTAACAGCCACCTTCCTATGTTTTCATGGTTGTAAAACATAATAAAACCTCCCACGTGGA
AGACTTGG

>23770_23770_12_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000398248_length(amino acids)=360AA_BP=282
MSRLERNGKWRPRRGVSCPTRGGSGGAMTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPAS
YIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKI
DYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVL
MSLYDPVESKFISFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFIPLWVESSASFLHTFATDSTILLWPTQLAINPTLVCESQPH


--------------------------------------------------------------
>23770_23770_13_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000398250_length(transcript)=1989nt_BP=876nt
CTCCGCCGCAAACTTTTTCCTCCCCATCCTGTCGCGGCTCGAAAGGAATGGAAAATGGCGGCCTAGACGCGGAGTTTCCTGCCCGACCCG
CGGCGGCTCCGGCGGCGCCATGACGCGCTGGGTGCCCACCAAGCGCGAGGAGAAGTACGGCGTGGCTTTTTATAACTATGATGCCAGAGG
AGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGGGTGGTACCGAGGTTACACGTTACGAAAAAA
GTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGGAAAAGGGCAACATGAAACAGTCATCCCGGG
TGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAGGCAGCTCTACGTGCAAGATAACAGGGAGAT
GTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGA
ACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGAATTCTAGATTTGGACCTGGTGGTTAGAGATGAAGATGGGAATATTTT
GGATCCAGAATTAACTAGCACGATTAGTCTCTTCAGAGCTCATGAAATAGCTTCTAAACAAGTGGAGGAAAGGTTACAAGAGGAAAAATC
TCAAAAGCAGAACATAGATATTAACAGACAAGCCAAGTTTGCTGCAACCCCTTCTCTGGCCTTGTTTGTGAACCTCAAAAATGTGGTTTG
TAAAATAGGAGAAGATGCTGAAGTCCTCATGTCTCTATATGACCCTGTGGAGTCCAAATTCATCAGTTTTACAGAGTTTTTGGATCCGTT
CCAGAGAGTCATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAAT
TTCTTTCCTCACACCCCTGGCTGTTATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGT
GTCCTTGGCTCTTGCTTTGAATGGAGTCTGCACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTT
TCCAGATGGAGTGATGAACTCGGAAATGCATTGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTC
CTCCTTTGCCTTTTCGGGCCTTGGCTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTG
GCGGCTCTGTGCTGCCATCCTGCCCTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTC
CTTTGTGGGTGGAGTCATCGGCCTCATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACC
CTACGTTAGTCTGCGAGTCCCAGCCTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCAC
CGAAGGCCCGGTATGACCAGTGTCCTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGG
TTTTCTGTAGTGTATTTTTCATCAGTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATG
TCTACTTCCAACATCCTTGAATTTGCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGC
TTGGCCGATTCGTCTATCTGAAATGTTTGCTGTAACAGCCACCTTCCTATGTTTTCATGGTTGTAAAACATAATAAAACCTCCCACGTGG
AAGACTTGG

>23770_23770_13_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000398250_length(amino acids)=535AA_BP=282
MSRLERNGKWRPRRGVSCPTRGGSGGAMTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPAS
YIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKI
DYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVL
MSLYDPVESKFISFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGV
CTNTIKLIVGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPL
YCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVSLRVPASLKKEERPTADSAPSLPLEGITEGPV

--------------------------------------------------------------
>23770_23770_14_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000439221_length(transcript)=1800nt_BP=876nt
CTCCGCCGCAAACTTTTTCCTCCCCATCCTGTCGCGGCTCGAAAGGAATGGAAAATGGCGGCCTAGACGCGGAGTTTCCTGCCCGACCCG
CGGCGGCTCCGGCGGCGCCATGACGCGCTGGGTGCCCACCAAGCGCGAGGAGAAGTACGGCGTGGCTTTTTATAACTATGATGCCAGAGG
AGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGGGTGGTACCGAGGTTACACGTTACGAAAAAA
GTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGGAAAAGGGCAACATGAAACAGTCATCCCGGG
TGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAGGCAGCTCTACGTGCAAGATAACAGGGAGAT
GTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGA
ACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGAATTCTAGATTTGGACCTGGTGGTTAGAGATGAAGATGGGAATATTTT
GGATCCAGAATTAACTAGCACGATTAGTCTCTTCAGAGCTCATGAAATAGCTTCTAAACAAGTGGAGGAAAGGTTACAAGAGGAAAAATC
TCAAAAGCAGAACATAGATATTAACAGACAAGCCAAGTTTGCTGCAACCCCTTCTCTGGCCTTGTTTGTGAACCTCAAAAATGTGGTTTG
TAAAATAGGAGAAGATGCTGAAGTCCTCATGTCTCTATATGACCCTGTGGAGTCCAAATTCATCAGTTTTACAGAGTTTTTGGATCCGTT
CCAGAGAGTCATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAAT
TTCTTTCCTCACACCCCTGGCTGTTATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGTTGC
CTTTTCGGGCCTTGGCTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTG
TGCTGCCATCCTGCCCTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTCCTTTGTGGG
TGGAGTCATCGGCCTCATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAG
TCTGCGAGTCCCAGCCTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCC
GGTATGACCAGTGTCCTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTA
GTGTATTTTTCATCAGTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCC
AACATCCTTGAATTTGCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGAT
TCGTCTATCTGAAATGTTTGCTGTAACAGCCACCTTCCTATGTTTTCATGGTTGTAAAACATAATAAAACCTCCCACGTGGAAGACTTGG


>23770_23770_14_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000439221_length(amino acids)=472AA_BP=282
MSRLERNGKWRPRRGVSCPTRGGSGGAMTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPAS
YIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKI
DYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVL
MSLYDPVESKFISFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLVAFSGLGFTTF
YLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVSLRVPASLKK
EERPTADSAPSLPLEGITEGPV

--------------------------------------------------------------
>23770_23770_15_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000541332_length(transcript)=2185nt_BP=876nt
CTCCGCCGCAAACTTTTTCCTCCCCATCCTGTCGCGGCTCGAAAGGAATGGAAAATGGCGGCCTAGACGCGGAGTTTCCTGCCCGACCCG
CGGCGGCTCCGGCGGCGCCATGACGCGCTGGGTGCCCACCAAGCGCGAGGAGAAGTACGGCGTGGCTTTTTATAACTATGATGCCAGAGG
AGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGGGTGGTACCGAGGTTACACGTTACGAAAAAA
GTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGGAAAAGGGCAACATGAAACAGTCATCCCGGG
TGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAGGCAGCTCTACGTGCAAGATAACAGGGAGAT
GTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGA
ACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGAATTCTAGATTTGGACCTGGTGGTTAGAGATGAAGATGGGAATATTTT
GGATCCAGAATTAACTAGCACGATTAGTCTCTTCAGAGCTCATGAAATAGCTTCTAAACAAGTGGAGGAAAGGTTACAAGAGGAAAAATC
TCAAAAGCAGAACATAGATATTAACAGACAAGCCAAGTTTGCTGCAACCCCTTCTCTGGCCTTGTTTGTGAACCTCAAAAATGTGGTTTG
TAAAATAGGAGAAGATGCTGAAGTCCTCATGTCTCTATATGACCCTGTGGAGTCCAAATTCATCAGTTTTACAGAGTTTTTGGATCCGTT
CCAGAGAGTCATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAAT
TTCTTTCCTCACACCCCTGGCTGTTATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGT
GTCCTTGGCTCTTGCTTTGAATGGAGTCTGCACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTT
TCCAGATGGAGTGATGAACTCGGAAATGCATTGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTC
CTCCTTTGCCTTTTCGGGCCTTGGCTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTG
GCGGCTCTGTGCTGCCATCCTGCCCTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGTTGG
CTGCTGTGTATGGCAGGGCCCACAGTCACATTTACCATCGGCTGCCAACCCCCGCCTCTGTCTGGGAACCTCTGAACCTTGACTGCCCAT
CTAAGTCCACCCGCCTCTGTGTTGGTGCCTAGGAGAGCGTAAGAAGCCTCAGCCCCTGGCTCACCCCTCCCTCCGGTCAAAGTCCACTGC
ATATCCTGCTTTCAGCCTCAAGAGAGGCATTCTCAGTCAGGACTTCTGCCCTCTTCCTGCCTCCAGGATAGCCCTGGTGTTTCCCCGTGA
TGTAATTCCCAGGGAAGATGGACGTTGATTGCTCCCAAGTCTCACTGGCATCCTTCCTTTGTTTTACTCAAGGGAACCTGTCTCTTCTCA
GCTTTCTGTGGTGTTCTGTGGTTCCTCCTGCTCAGCATATTTATAGACTCCAACTTTTCCTTCCCACTCTGGTCTAGTGATCCTCAGTTG
TTGCCTGAATCATTGCAGAAGCCTCTCAGCCTGGCTCCCTCCTTCCTTCTTTGGCCCTCAACTGCATTTGGAATGTGCCTTTAGAGCCTG
CGTTAGCACATGTCACTTTTGCAAAAATCCTCCAGTGATTCTCATTTCACTCAGCATCACAGCCTGTGTCCTGCCATGGTCCATAAGATC
TGCTCCCTCCGTACTTCTTTGATGCTATGTTCAAGCTACTTGTCCTCCTCGTTCACATGATTGCATCGCTTGAGCTTCTTGCTACTCCTT
GAACAGGCCCGTCCCATCCCACCTC

>23770_23770_15_DOCK1-PPAPDC1A_DOCK1_chr10_128796513_ENST00000280333_PPAPDC1A_chr10_122263330_ENST00000541332_length(amino acids)=497AA_BP=282
MSRLERNGKWRPRRGVSCPTRGGSGGAMTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPAS
YIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKI
DYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVL
MSLYDPVESKFISFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGV
CTNTIKLIVGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPL
YCAMMIALSRMCDYKHHWQVGCCVWQGPQSHLPSAANPRLCLGTSEP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for DOCK1-PPAPDC1A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneDOCK1chr10:128788867chr10:122263330ENST00000280333+6521837_1852157.666666666666661866.0NCK2 (minor)
HgeneDOCK1chr10:128796513chr10:122263329ENST00000280333+8521837_1852255.666666666666661866.0NCK2 (minor)
HgeneDOCK1chr10:128796513chr10:122263330ENST00000280333+8521837_1852255.666666666666661866.0NCK2 (minor)
HgeneDOCK1chr10:128788867chr10:122263330ENST00000280333+6521793_1819157.666666666666661866.0NCK2 second and third SH3 domain (minor)
HgeneDOCK1chr10:128796513chr10:122263329ENST00000280333+8521793_1819255.666666666666661866.0NCK2 second and third SH3 domain (minor)
HgeneDOCK1chr10:128796513chr10:122263330ENST00000280333+8521793_1819255.666666666666661866.0NCK2 second and third SH3 domain (minor)
HgeneDOCK1chr10:128788867chr10:122263330ENST00000280333+6521820_1836157.666666666666661866.0NCK2 third SH3 domain (major)
HgeneDOCK1chr10:128796513chr10:122263329ENST00000280333+8521820_1836255.666666666666661866.0NCK2 third SH3 domain (major)
HgeneDOCK1chr10:128796513chr10:122263330ENST00000280333+8521820_1836255.666666666666661866.0NCK2 third SH3 domain (major)


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DOCK1-PPAPDC1A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DOCK1-PPAPDC1A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneDOCK1C0013146Drug abuse1CTD_human
HgeneDOCK1C0013170Drug habituation1CTD_human
HgeneDOCK1C0013222Drug Use Disorders1CTD_human
HgeneDOCK1C0029231Organic Mental Disorders, Substance-Induced1CTD_human
HgeneDOCK1C0038580Substance Dependence1CTD_human
HgeneDOCK1C0038586Substance Use Disorders1CTD_human
HgeneDOCK1C0236969Substance-Related Disorders1CTD_human
HgeneDOCK1C0740858Substance abuse problem1CTD_human
HgeneDOCK1C1510472Drug Dependence1CTD_human
HgeneDOCK1C4316881Prescription Drug Abuse1CTD_human