|
||||||
|
 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:DPP6-IFIT3 (FusionGDB2 ID:HG1804TG3437) |
Fusion Gene Summary for DPP6-IFIT3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DPP6-IFIT3 | Fusion gene ID: hg1804tg3437 | Hgene | Tgene | Gene symbol | DPP6 | IFIT3 | Gene ID | 1804 | 3437 |
| Gene name | dipeptidyl peptidase like 6 | interferon induced protein with tetratricopeptide repeats 3 | |
| Synonyms | DPL1|DPPX|MRD33|VF2 | CIG-49|GARG-49|IFI60|IFIT4|IRG2|ISG60|P60|RIG-G|cig41 | |
| Cytomap | ('DPP6')('IFIT3') 7q36.2 | 10q23.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | dipeptidyl aminopeptidase-like protein 6DPP VIdipeptidyl aminopeptidase IV-related proteindipeptidyl peptidase IV-related proteindipeptidyl peptidase VIdipeptidyl-peptidase 6 | interferon-induced protein with tetratricopeptide repeats 3CIG49IFI-60KIFIT-3IFIT-4ISG-60interferon-induced 60 kDa proteininterferon-induced protein with tetratricopeptide repeats 4retinoic acid-induced gene G protein | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | P42658 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000332007, ENST00000377770, ENST00000404039, ENST00000406326, ENST00000427557, ENST00000496611, | ||
| Fusion gene scores | * DoF score | 9 X 10 X 5=450 | 2 X 2 X 2=8 |
| # samples | 12 | 2 | |
| ** MAII score | log2(12/450*10)=-1.90689059560852 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: DPP6 [Title/Abstract] AND IFIT3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | DPP6(154461151)-IFIT3(91098418), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | DPP6 | GO:1901379 | regulation of potassium ion transmembrane transport | 18364354 |
| Tgene | IFIT3 | GO:0008285 | negative regulation of cell proliferation | 17050680 |
| Tgene | IFIT3 | GO:0043066 | negative regulation of apoptotic process | 21190939 |
| Fusion gene breakpoints across DPP6 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
| Fusion gene breakpoints across IFIT3 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | PCPG | TCGA-QR-A70V-01A | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + |
Top |
Fusion Gene ORF analysis for DPP6-IFIT3 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000332007 | ENST00000371811 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + |
| In-frame | ENST00000332007 | ENST00000371818 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + |
| In-frame | ENST00000377770 | ENST00000371811 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + |
| In-frame | ENST00000377770 | ENST00000371818 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + |
| In-frame | ENST00000404039 | ENST00000371811 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + |
| In-frame | ENST00000404039 | ENST00000371818 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + |
| intron-3CDS | ENST00000406326 | ENST00000371811 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + |
| intron-3CDS | ENST00000406326 | ENST00000371818 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + |
| intron-3CDS | ENST00000427557 | ENST00000371811 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + |
| intron-3CDS | ENST00000427557 | ENST00000371818 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + |
| intron-3CDS | ENST00000496611 | ENST00000371811 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + |
| intron-3CDS | ENST00000496611 | ENST00000371818 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000404039 | DPP6 | chr7 | 154461151 | - | ENST00000371818 | IFIT3 | chr10 | 91098418 | + | 3468 | 1157 | 1071 | 2624 | 517 |
| ENST00000404039 | DPP6 | chr7 | 154461151 | - | ENST00000371811 | IFIT3 | chr10 | 91098418 | + | 3468 | 1157 | 1071 | 2624 | 517 |
| ENST00000377770 | DPP6 | chr7 | 154461151 | - | ENST00000371818 | IFIT3 | chr10 | 91098418 | + | 3214 | 903 | 817 | 2370 | 517 |
| ENST00000377770 | DPP6 | chr7 | 154461151 | - | ENST00000371811 | IFIT3 | chr10 | 91098418 | + | 3214 | 903 | 817 | 2370 | 517 |
| ENST00000332007 | DPP6 | chr7 | 154461151 | - | ENST00000371818 | IFIT3 | chr10 | 91098418 | + | 3272 | 961 | 875 | 2428 | 517 |
| ENST00000332007 | DPP6 | chr7 | 154461151 | - | ENST00000371811 | IFIT3 | chr10 | 91098418 | + | 3272 | 961 | 875 | 2428 | 517 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000404039 | ENST00000371818 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + | 0.00197496 | 0.99802506 |
| ENST00000404039 | ENST00000371811 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + | 0.00197496 | 0.99802506 |
| ENST00000377770 | ENST00000371818 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + | 0.002296939 | 0.99770314 |
| ENST00000377770 | ENST00000371811 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + | 0.002296939 | 0.99770314 |
| ENST00000332007 | ENST00000371818 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + | 0.002458472 | 0.99754155 |
| ENST00000332007 | ENST00000371811 | DPP6 | chr7 | 154461151 | - | IFIT3 | chr10 | 91098418 | + | 0.002458472 | 0.99754155 |
Top |
Fusion Genomic Features for DPP6-IFIT3 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
 |
Top |
Fusion Protein Features for DPP6-IFIT3 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:154461151/chr10:91098418) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| DPP6 | . |
| FUNCTION: Promotes cell surface expression of the potassium channel KCND2 (PubMed:15454437, PubMed:19441798). Modulates the activity and gating characteristics of the potassium channel KCND2 (PubMed:18364354). Has no dipeptidyl aminopeptidase activity (PubMed:8103397, PubMed:15476821). {ECO:0000269|PubMed:15454437, ECO:0000269|PubMed:18364354, ECO:0000269|PubMed:8103397, ECO:0000305|PubMed:15476821}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | DPP6 | chr7:154461151 | chr10:91098418 | ENST00000332007 | - | 7 | 26 | 1_95 | 192 | 804.0 | Topological domain | Cytoplasmic |
| Hgene | DPP6 | chr7:154461151 | chr10:91098418 | ENST00000377770 | - | 7 | 26 | 1_95 | 254 | 866.0 | Topological domain | Cytoplasmic |
| Hgene | DPP6 | chr7:154461151 | chr10:91098418 | ENST00000332007 | - | 7 | 26 | 96_116 | 192 | 804.0 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| Hgene | DPP6 | chr7:154461151 | chr10:91098418 | ENST00000377770 | - | 7 | 26 | 96_116 | 254 | 866.0 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| Tgene | IFIT3 | chr7:154461151 | chr10:91098418 | ENST00000371811 | 0 | 2 | 136_169 | 1 | 491.0 | Repeat | Note=TPR 3 | |
| Tgene | IFIT3 | chr7:154461151 | chr10:91098418 | ENST00000371811 | 0 | 2 | 172_206 | 1 | 491.0 | Repeat | Note=TPR 4 | |
| Tgene | IFIT3 | chr7:154461151 | chr10:91098418 | ENST00000371811 | 0 | 2 | 207_240 | 1 | 491.0 | Repeat | Note=TPR 5 | |
| Tgene | IFIT3 | chr7:154461151 | chr10:91098418 | ENST00000371811 | 0 | 2 | 241_274 | 1 | 491.0 | Repeat | Note=TPR 6 | |
| Tgene | IFIT3 | chr7:154461151 | chr10:91098418 | ENST00000371811 | 0 | 2 | 415_448 | 1 | 491.0 | Repeat | Note=TPR 7 | |
| Tgene | IFIT3 | chr7:154461151 | chr10:91098418 | ENST00000371811 | 0 | 2 | 450_481 | 1 | 491.0 | Repeat | Note=TPR 8 | |
| Tgene | IFIT3 | chr7:154461151 | chr10:91098418 | ENST00000371811 | 0 | 2 | 51_84 | 1 | 491.0 | Repeat | Note=TPR 1 | |
| Tgene | IFIT3 | chr7:154461151 | chr10:91098418 | ENST00000371811 | 0 | 2 | 94_127 | 1 | 491.0 | Repeat | Note=TPR 2 | |
| Tgene | IFIT3 | chr7:154461151 | chr10:91098418 | ENST00000371818 | 0 | 2 | 136_169 | 1 | 491.0 | Repeat | Note=TPR 3 | |
| Tgene | IFIT3 | chr7:154461151 | chr10:91098418 | ENST00000371818 | 0 | 2 | 172_206 | 1 | 491.0 | Repeat | Note=TPR 4 | |
| Tgene | IFIT3 | chr7:154461151 | chr10:91098418 | ENST00000371818 | 0 | 2 | 207_240 | 1 | 491.0 | Repeat | Note=TPR 5 | |
| Tgene | IFIT3 | chr7:154461151 | chr10:91098418 | ENST00000371818 | 0 | 2 | 241_274 | 1 | 491.0 | Repeat | Note=TPR 6 | |
| Tgene | IFIT3 | chr7:154461151 | chr10:91098418 | ENST00000371818 | 0 | 2 | 415_448 | 1 | 491.0 | Repeat | Note=TPR 7 | |
| Tgene | IFIT3 | chr7:154461151 | chr10:91098418 | ENST00000371818 | 0 | 2 | 450_481 | 1 | 491.0 | Repeat | Note=TPR 8 | |
| Tgene | IFIT3 | chr7:154461151 | chr10:91098418 | ENST00000371818 | 0 | 2 | 51_84 | 1 | 491.0 | Repeat | Note=TPR 1 | |
| Tgene | IFIT3 | chr7:154461151 | chr10:91098418 | ENST00000371818 | 0 | 2 | 94_127 | 1 | 491.0 | Repeat | Note=TPR 2 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | DPP6 | chr7:154461151 | chr10:91098418 | ENST00000332007 | - | 7 | 26 | 117_865 | 192 | 804.0 | Topological domain | Extracellular |
| Hgene | DPP6 | chr7:154461151 | chr10:91098418 | ENST00000377770 | - | 7 | 26 | 117_865 | 254 | 866.0 | Topological domain | Extracellular |
Top |
Fusion Gene Sequence for DPP6-IFIT3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >24030_24030_1_DPP6-IFIT3_DPP6_chr7_154461151_ENST00000332007_IFIT3_chr10_91098418_ENST00000371811_length(transcript)=3272nt_BP=961nt TGCGCCGTGGGCGCCGGGCCGGGAGGCGGGCGAGGAGGCAGCGCGCATCACTCGGGTCCCCTTCCTGCACCCAGCCGCCACTTGCCGGTT GCTAAGCAGTTATCATTGTTTCTGTGGCGATTGCAGAGGCTGTTGCTAATTGGAGAAGCCCCACTAAGCAGCGGCAGCTTCCTGCTTCGG ATCCTCTCTCTGCTGCTTGCATTTAAAGAGCAAACTCGTCTTGTCTACCCACCCTCCCTCCCCCATCCTCCCCAAAATAGCCTTGTGATT TCGGAAGTATGGACTAAAATCACACTCCTCCTTACCTTACCGCTTGGACTCTGGTGGCTCCCAACTCGCCGTCAGACCCCACCTGCCCCG GTGGTGGGAAGCGCCTGGACAGACCATGACCACAGCCAAGGAGCCAAGCGCTTCGGGGAAATCCGTGCAGCAGCAGGAACAGGAGCTGGT GGGGAGTAACCCTCCGCAGAGGAATTGGAAAGGAATAGCAATTGCACTGCTTGTCATTCTGGTCATCTGCTCCTTGATCGTCACCTCGGT CATACTTCTGACACCAGCGGAAGATAATAGTCTGTCTCAAAAGAAGAAGGTCACTGTAGAAGATCTCTTCAGTGAAGACTTCAAAATTCA TGACCCCGAGGCTAAGTGGATAAGTGATACAGAATTCATCTACAGAGAACAGAAAGGAACAGTGAGACTGTGGAATGTTGAAACAAATAC TTCTACTGTCTTAATAGAAGGCAAAAAAATTGAATCATTAAGAGCCATCAGATATGAAATATCTCCAGATAGAGAGTATGCACTTTTTTC ATACAATGTGGAACCCATATATCAACACTCGTATACTGGATATTACGTCCTGAGCAAAATTCCTCATGGGGATCCTCAAAGTCTGGACCC ACCAGAAGTCAGCAATGCAAAACTTCAGTATGCAGGATGGGGCCCTAAAGGCCAACAGCTGTGAGGTCACCAAGAATTCCCTGGAGAAAA TCCTTCCACAGCTGAAATGCCATTTCACCTGGAACTTATTCAAGGAAGACAGTGTCTCAAGGGATCTAGAAGATAGAGTGTGTAACCAGA TTGAATTTTTAAACACTGAGTTCAAAGCTACAATGTACAACTTGTTGGCCTACATAAAACACCTAGATGGTAACAACGAGGCAGCCCTGG AATGCTTACGGCAAGCTGAAGAGTTAATCCAGCAAGAACATGCTGACCAAGCAGAAATCAGAAGTCTAGTCACTTGGGGAAACTACGCCT GGGTCTACTATCACTTGGGCAGACTCTCAGATGCTCAGATTTATGTAGATAAGGTGAAACAAACCTGCAAGAAATTTTCAAATCCATACA GTATTGAGTATTCTGAACTTGACTGTGAGGAAGGGTGGACACAACTGAAGTGTGGAAGAAATGAAAGGGCGAAGGTGTGTTTTGAGAAGG CTCTGGAAGAAAAGCCCAACAACCCAGAATTCTCCTCTGGACTGGCAATTGCGATGTACCATCTGGATAATCACCCAGAGAAACAGTTCT CTACTGATGTTTTGAAGCAGGCCATTGAGCTGAGTCCTGATAACCAATACGTCAAGGTTCTCTTGGGCCTGAAACTGCAGAAGATGAATA AAGAAGCTGAAGGAGAGCAGTTTGTTGAAGAAGCCTTGGAAAAGTCTCCTTGCCAAACAGATGTCCTCCGCAGTGCAGCCAAATTTTACA GAAGAAAAGGTGACCTAGACAAAGCTATTGAACTGTTTCAACGGGTGTTGGAATCCACACCAAACAATGGCTACCTCTATCACCAGATTG GGTGCTGCTACAAGGCAAAAGTAAGACAAATGCAGAATACAGGAGAATCTGAAGCTAGTGGAAATAAAGAGATGATTGAAGCACTAAAGC AATATGCTATGGACTATTCGAATAAAGCTCTTGAGAAGGGACTGAATCCTCTGAATGCATACTCCGATCTCGCTGAGTTCCTGGAGACGG AATGTTATCAGACACCATTCAATAAGGAAGTCCCTGATGCTGAAAAGCAACAATCCCATCAGCGCTACTGCAACCTTCAGAAATATAATG GGAAGTCTGAAGACACTGCTGTGCAACATGGTTTAGAGGGTTTGTCCATAAGCAAAAAATCAACTGACAAGGAAGAGATCAAAGACCAAC CACAGAATGTATCTGAAAATCTGCTTCCACAAAATGCACCAAATTATTGGTATCTTCAAGGATTAATTCATAAGCAGAATGGAGATCTGC TGCAAGCAGCCAAATGTTATGAGAAGGAACTGGGCCGCCTGCTAAGGGATGCCCCTTCAGGCATAGGCAGTATTTTCCTGTCAGCATCTG AGCTTGAGGATGGTAGTGAGGAAATGGGCCAGGGCGCAGTCAGCTCCAGTCCCAGAGAGCTCCTCTCTAACTCAGAGCAACTGAACTGAG ACAGAGGAGGAAAACAGAGCATCAGAAGCCTGCAGTGGTGGTTGTGACGGGTAGGACGATAGGAAGACAGGGGGCCCCAACCTGGGATTG CTGAGCAGGGAAGCTTTGCATGTTGCTCTAAGGTACATTTTTAAAGAGTTGTTTTTTGGCCGGGCGCAGTGGCTCATGCCTGTAATCCCA GCACTTTGGGAGGCCGAGGTGGGCGGATCACGAGGTCTGGAGTTTGAGACCATCCTGGCTAACACAGTGAAATCCCGTCTCTACTAAAAA TACAAAAAATTAGCCAGGCGTGGTGGCTGGCACCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCGTGAACCTGGAAGGA AGAGGTTGCAGTGAGCCAAGATTGCGCCCCTGCACTCCAGCCTGGGCAACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAA AAGAGTTGTTTTCTCATGTTCATTATAGTTCATTACAGTTACATAGTCCGAAGGTCTTACAACTAATCACTGGTAGCAATAAATGCTTCA GGCCCACATGATGCTGATTAGTTCTCAGTTTTCATTCAGTTCACAATATAACCACCATTCCTGCCCTCCCTGCCAAGGGTCATAAATGGT GACTGCCTAACAACAAAATTTGCAGTCTCATCTCATTTTCATCCAGACTTCTGGAACTCAAAGATTAACTTTTGACTAACCCTGGAATAT CTCTTATCTCACTTATAGCTTCAGGCATGTATTTATATGTATTCTTGATAGCAATACCATAATCAATGTGTATTCCTGATAGTAATGCTA CAATAAATCCAAACATTTCAACTCTGTTAGAA >24030_24030_1_DPP6-IFIT3_DPP6_chr7_154461151_ENST00000332007_IFIT3_chr10_91098418_ENST00000371811_length(amino acids)=517AA_BP=29 MGILKVWTHQKSAMQNFSMQDGALKANSCEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKHL DGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNE RAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDV LRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYS DLAEFLETECYQTPFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYLQGL IHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN -------------------------------------------------------------- >24030_24030_2_DPP6-IFIT3_DPP6_chr7_154461151_ENST00000332007_IFIT3_chr10_91098418_ENST00000371818_length(transcript)=3272nt_BP=961nt TGCGCCGTGGGCGCCGGGCCGGGAGGCGGGCGAGGAGGCAGCGCGCATCACTCGGGTCCCCTTCCTGCACCCAGCCGCCACTTGCCGGTT GCTAAGCAGTTATCATTGTTTCTGTGGCGATTGCAGAGGCTGTTGCTAATTGGAGAAGCCCCACTAAGCAGCGGCAGCTTCCTGCTTCGG ATCCTCTCTCTGCTGCTTGCATTTAAAGAGCAAACTCGTCTTGTCTACCCACCCTCCCTCCCCCATCCTCCCCAAAATAGCCTTGTGATT TCGGAAGTATGGACTAAAATCACACTCCTCCTTACCTTACCGCTTGGACTCTGGTGGCTCCCAACTCGCCGTCAGACCCCACCTGCCCCG GTGGTGGGAAGCGCCTGGACAGACCATGACCACAGCCAAGGAGCCAAGCGCTTCGGGGAAATCCGTGCAGCAGCAGGAACAGGAGCTGGT GGGGAGTAACCCTCCGCAGAGGAATTGGAAAGGAATAGCAATTGCACTGCTTGTCATTCTGGTCATCTGCTCCTTGATCGTCACCTCGGT CATACTTCTGACACCAGCGGAAGATAATAGTCTGTCTCAAAAGAAGAAGGTCACTGTAGAAGATCTCTTCAGTGAAGACTTCAAAATTCA TGACCCCGAGGCTAAGTGGATAAGTGATACAGAATTCATCTACAGAGAACAGAAAGGAACAGTGAGACTGTGGAATGTTGAAACAAATAC TTCTACTGTCTTAATAGAAGGCAAAAAAATTGAATCATTAAGAGCCATCAGATATGAAATATCTCCAGATAGAGAGTATGCACTTTTTTC ATACAATGTGGAACCCATATATCAACACTCGTATACTGGATATTACGTCCTGAGCAAAATTCCTCATGGGGATCCTCAAAGTCTGGACCC ACCAGAAGTCAGCAATGCAAAACTTCAGTATGCAGGATGGGGCCCTAAAGGCCAACAGCTGTGAGGTCACCAAGAATTCCCTGGAGAAAA TCCTTCCACAGCTGAAATGCCATTTCACCTGGAACTTATTCAAGGAAGACAGTGTCTCAAGGGATCTAGAAGATAGAGTGTGTAACCAGA TTGAATTTTTAAACACTGAGTTCAAAGCTACAATGTACAACTTGTTGGCCTACATAAAACACCTAGATGGTAACAACGAGGCAGCCCTGG AATGCTTACGGCAAGCTGAAGAGTTAATCCAGCAAGAACATGCTGACCAAGCAGAAATCAGAAGTCTAGTCACTTGGGGAAACTACGCCT GGGTCTACTATCACTTGGGCAGACTCTCAGATGCTCAGATTTATGTAGATAAGGTGAAACAAACCTGCAAGAAATTTTCAAATCCATACA GTATTGAGTATTCTGAACTTGACTGTGAGGAAGGGTGGACACAACTGAAGTGTGGAAGAAATGAAAGGGCGAAGGTGTGTTTTGAGAAGG CTCTGGAAGAAAAGCCCAACAACCCAGAATTCTCCTCTGGACTGGCAATTGCGATGTACCATCTGGATAATCACCCAGAGAAACAGTTCT CTACTGATGTTTTGAAGCAGGCCATTGAGCTGAGTCCTGATAACCAATACGTCAAGGTTCTCTTGGGCCTGAAACTGCAGAAGATGAATA AAGAAGCTGAAGGAGAGCAGTTTGTTGAAGAAGCCTTGGAAAAGTCTCCTTGCCAAACAGATGTCCTCCGCAGTGCAGCCAAATTTTACA GAAGAAAAGGTGACCTAGACAAAGCTATTGAACTGTTTCAACGGGTGTTGGAATCCACACCAAACAATGGCTACCTCTATCACCAGATTG GGTGCTGCTACAAGGCAAAAGTAAGACAAATGCAGAATACAGGAGAATCTGAAGCTAGTGGAAATAAAGAGATGATTGAAGCACTAAAGC AATATGCTATGGACTATTCGAATAAAGCTCTTGAGAAGGGACTGAATCCTCTGAATGCATACTCCGATCTCGCTGAGTTCCTGGAGACGG AATGTTATCAGACACCATTCAATAAGGAAGTCCCTGATGCTGAAAAGCAACAATCCCATCAGCGCTACTGCAACCTTCAGAAATATAATG GGAAGTCTGAAGACACTGCTGTGCAACATGGTTTAGAGGGTTTGTCCATAAGCAAAAAATCAACTGACAAGGAAGAGATCAAAGACCAAC CACAGAATGTATCTGAAAATCTGCTTCCACAAAATGCACCAAATTATTGGTATCTTCAAGGATTAATTCATAAGCAGAATGGAGATCTGC TGCAAGCAGCCAAATGTTATGAGAAGGAACTGGGCCGCCTGCTAAGGGATGCCCCTTCAGGCATAGGCAGTATTTTCCTGTCAGCATCTG AGCTTGAGGATGGTAGTGAGGAAATGGGCCAGGGCGCAGTCAGCTCCAGTCCCAGAGAGCTCCTCTCTAACTCAGAGCAACTGAACTGAG ACAGAGGAGGAAAACAGAGCATCAGAAGCCTGCAGTGGTGGTTGTGACGGGTAGGACGATAGGAAGACAGGGGGCCCCAACCTGGGATTG CTGAGCAGGGAAGCTTTGCATGTTGCTCTAAGGTACATTTTTAAAGAGTTGTTTTTTGGCCGGGCGCAGTGGCTCATGCCTGTAATCCCA GCACTTTGGGAGGCCGAGGTGGGCGGATCACGAGGTCTGGAGTTTGAGACCATCCTGGCTAACACAGTGAAATCCCGTCTCTACTAAAAA TACAAAAAATTAGCCAGGCGTGGTGGCTGGCACCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCGTGAACCTGGAAGGA AGAGGTTGCAGTGAGCCAAGATTGCGCCCCTGCACTCCAGCCTGGGCAACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAA AAGAGTTGTTTTCTCATGTTCATTATAGTTCATTACAGTTACATAGTCCGAAGGTCTTACAACTAATCACTGGTAGCAATAAATGCTTCA GGCCCACATGATGCTGATTAGTTCTCAGTTTTCATTCAGTTCACAATATAACCACCATTCCTGCCCTCCCTGCCAAGGGTCATAAATGGT GACTGCCTAACAACAAAATTTGCAGTCTCATCTCATTTTCATCCAGACTTCTGGAACTCAAAGATTAACTTTTGACTAACCCTGGAATAT CTCTTATCTCACTTATAGCTTCAGGCATGTATTTATATGTATTCTTGATAGCAATACCATAATCAATGTGTATTCCTGATAGTAATGCTA CAATAAATCCAAACATTTCAACTCTGTTAGAA >24030_24030_2_DPP6-IFIT3_DPP6_chr7_154461151_ENST00000332007_IFIT3_chr10_91098418_ENST00000371818_length(amino acids)=517AA_BP=29 MGILKVWTHQKSAMQNFSMQDGALKANSCEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKHL DGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNE RAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDV LRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYS DLAEFLETECYQTPFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYLQGL IHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN -------------------------------------------------------------- >24030_24030_3_DPP6-IFIT3_DPP6_chr7_154461151_ENST00000377770_IFIT3_chr10_91098418_ENST00000371811_length(transcript)=3214nt_BP=903nt GCTTGCCTTGCTGCTGCTGCTGCTGCTGCCTCCCCACCGCCTTTTTTTTTTTTTAATCTGGAGCGGGGTGGGGAGTGGGAACCGGAGAGA AAGCAAAATATTAAAAAGCCCCAAAGACAGCCAGCAGGAGCGCGGTGCCCGATGGCTTCGCTGTACCAGAGGTTCACTGGCAAGATCAAC ACCTCGAGGTCCTTCCCCGCGCCCCCGGAGGCGAGTCACCTCCTGGGCGGCCAGGGGCCCGAGGAGGACGGCGGCGCAGGAGCCAAGCCC CTCGGCCCGCGGGCGCAGGCGGCGGCGCCCCGGGAGCGCGGCGGCGGCGGCGGCGGCGCGGGTGGCCGGCCCCGGTTCCAGTACCAGGCG CGGAGCGATGGTGACGAGGAGGACGAGCTGGTGGGGAGTAACCCTCCGCAGAGGAATTGGAAAGGAATAGCAATTGCACTGCTTGTCATT CTGGTCATCTGCTCCTTGATCGTCACCTCGGTCATACTTCTGACACCAGCGGAAGATAATAGTCTGTCTCAAAAGAAGAAGGTCACTGTA GAAGATCTCTTCAGTGAAGACTTCAAAATTCATGACCCCGAGGCTAAGTGGATAAGTGATACAGAATTCATCTACAGAGAACAGAAAGGA ACAGTGAGACTGTGGAATGTTGAAACAAATACTTCTACTGTCTTAATAGAAGGCAAAAAAATTGAATCATTAAGAGCCATCAGATATGAA ATATCTCCAGATAGAGAGTATGCACTTTTTTCATACAATGTGGAACCCATATATCAACACTCGTATACTGGATATTACGTCCTGAGCAAA ATTCCTCATGGGGATCCTCAAAGTCTGGACCCACCAGAAGTCAGCAATGCAAAACTTCAGTATGCAGGATGGGGCCCTAAAGGCCAACAG CTGTGAGGTCACCAAGAATTCCCTGGAGAAAATCCTTCCACAGCTGAAATGCCATTTCACCTGGAACTTATTCAAGGAAGACAGTGTCTC AAGGGATCTAGAAGATAGAGTGTGTAACCAGATTGAATTTTTAAACACTGAGTTCAAAGCTACAATGTACAACTTGTTGGCCTACATAAA ACACCTAGATGGTAACAACGAGGCAGCCCTGGAATGCTTACGGCAAGCTGAAGAGTTAATCCAGCAAGAACATGCTGACCAAGCAGAAAT CAGAAGTCTAGTCACTTGGGGAAACTACGCCTGGGTCTACTATCACTTGGGCAGACTCTCAGATGCTCAGATTTATGTAGATAAGGTGAA ACAAACCTGCAAGAAATTTTCAAATCCATACAGTATTGAGTATTCTGAACTTGACTGTGAGGAAGGGTGGACACAACTGAAGTGTGGAAG AAATGAAAGGGCGAAGGTGTGTTTTGAGAAGGCTCTGGAAGAAAAGCCCAACAACCCAGAATTCTCCTCTGGACTGGCAATTGCGATGTA CCATCTGGATAATCACCCAGAGAAACAGTTCTCTACTGATGTTTTGAAGCAGGCCATTGAGCTGAGTCCTGATAACCAATACGTCAAGGT TCTCTTGGGCCTGAAACTGCAGAAGATGAATAAAGAAGCTGAAGGAGAGCAGTTTGTTGAAGAAGCCTTGGAAAAGTCTCCTTGCCAAAC AGATGTCCTCCGCAGTGCAGCCAAATTTTACAGAAGAAAAGGTGACCTAGACAAAGCTATTGAACTGTTTCAACGGGTGTTGGAATCCAC ACCAAACAATGGCTACCTCTATCACCAGATTGGGTGCTGCTACAAGGCAAAAGTAAGACAAATGCAGAATACAGGAGAATCTGAAGCTAG TGGAAATAAAGAGATGATTGAAGCACTAAAGCAATATGCTATGGACTATTCGAATAAAGCTCTTGAGAAGGGACTGAATCCTCTGAATGC ATACTCCGATCTCGCTGAGTTCCTGGAGACGGAATGTTATCAGACACCATTCAATAAGGAAGTCCCTGATGCTGAAAAGCAACAATCCCA TCAGCGCTACTGCAACCTTCAGAAATATAATGGGAAGTCTGAAGACACTGCTGTGCAACATGGTTTAGAGGGTTTGTCCATAAGCAAAAA ATCAACTGACAAGGAAGAGATCAAAGACCAACCACAGAATGTATCTGAAAATCTGCTTCCACAAAATGCACCAAATTATTGGTATCTTCA AGGATTAATTCATAAGCAGAATGGAGATCTGCTGCAAGCAGCCAAATGTTATGAGAAGGAACTGGGCCGCCTGCTAAGGGATGCCCCTTC AGGCATAGGCAGTATTTTCCTGTCAGCATCTGAGCTTGAGGATGGTAGTGAGGAAATGGGCCAGGGCGCAGTCAGCTCCAGTCCCAGAGA GCTCCTCTCTAACTCAGAGCAACTGAACTGAGACAGAGGAGGAAAACAGAGCATCAGAAGCCTGCAGTGGTGGTTGTGACGGGTAGGACG ATAGGAAGACAGGGGGCCCCAACCTGGGATTGCTGAGCAGGGAAGCTTTGCATGTTGCTCTAAGGTACATTTTTAAAGAGTTGTTTTTTG GCCGGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACGAGGTCTGGAGTTTGAGACCATCCTGG CTAACACAGTGAAATCCCGTCTCTACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGCTGGCACCTGTAGTCCCAGCTACTTGGGAGGC TGAGGCAGGAGAATGGCGTGAACCTGGAAGGAAGAGGTTGCAGTGAGCCAAGATTGCGCCCCTGCACTCCAGCCTGGGCAACAGAGCAAG ACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAAGAGTTGTTTTCTCATGTTCATTATAGTTCATTACAGTTACATAGTCCGAAGGTCTT ACAACTAATCACTGGTAGCAATAAATGCTTCAGGCCCACATGATGCTGATTAGTTCTCAGTTTTCATTCAGTTCACAATATAACCACCAT TCCTGCCCTCCCTGCCAAGGGTCATAAATGGTGACTGCCTAACAACAAAATTTGCAGTCTCATCTCATTTTCATCCAGACTTCTGGAACT CAAAGATTAACTTTTGACTAACCCTGGAATATCTCTTATCTCACTTATAGCTTCAGGCATGTATTTATATGTATTCTTGATAGCAATACC ATAATCAATGTGTATTCCTGATAGTAATGCTACAATAAATCCAAACATTTCAACTCTGTTAGAA >24030_24030_3_DPP6-IFIT3_DPP6_chr7_154461151_ENST00000377770_IFIT3_chr10_91098418_ENST00000371811_length(amino acids)=517AA_BP=29 MGILKVWTHQKSAMQNFSMQDGALKANSCEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKHL DGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNE RAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDV LRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYS DLAEFLETECYQTPFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYLQGL IHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN -------------------------------------------------------------- >24030_24030_4_DPP6-IFIT3_DPP6_chr7_154461151_ENST00000377770_IFIT3_chr10_91098418_ENST00000371818_length(transcript)=3214nt_BP=903nt GCTTGCCTTGCTGCTGCTGCTGCTGCTGCCTCCCCACCGCCTTTTTTTTTTTTTAATCTGGAGCGGGGTGGGGAGTGGGAACCGGAGAGA AAGCAAAATATTAAAAAGCCCCAAAGACAGCCAGCAGGAGCGCGGTGCCCGATGGCTTCGCTGTACCAGAGGTTCACTGGCAAGATCAAC ACCTCGAGGTCCTTCCCCGCGCCCCCGGAGGCGAGTCACCTCCTGGGCGGCCAGGGGCCCGAGGAGGACGGCGGCGCAGGAGCCAAGCCC CTCGGCCCGCGGGCGCAGGCGGCGGCGCCCCGGGAGCGCGGCGGCGGCGGCGGCGGCGCGGGTGGCCGGCCCCGGTTCCAGTACCAGGCG CGGAGCGATGGTGACGAGGAGGACGAGCTGGTGGGGAGTAACCCTCCGCAGAGGAATTGGAAAGGAATAGCAATTGCACTGCTTGTCATT CTGGTCATCTGCTCCTTGATCGTCACCTCGGTCATACTTCTGACACCAGCGGAAGATAATAGTCTGTCTCAAAAGAAGAAGGTCACTGTA GAAGATCTCTTCAGTGAAGACTTCAAAATTCATGACCCCGAGGCTAAGTGGATAAGTGATACAGAATTCATCTACAGAGAACAGAAAGGA ACAGTGAGACTGTGGAATGTTGAAACAAATACTTCTACTGTCTTAATAGAAGGCAAAAAAATTGAATCATTAAGAGCCATCAGATATGAA ATATCTCCAGATAGAGAGTATGCACTTTTTTCATACAATGTGGAACCCATATATCAACACTCGTATACTGGATATTACGTCCTGAGCAAA ATTCCTCATGGGGATCCTCAAAGTCTGGACCCACCAGAAGTCAGCAATGCAAAACTTCAGTATGCAGGATGGGGCCCTAAAGGCCAACAG CTGTGAGGTCACCAAGAATTCCCTGGAGAAAATCCTTCCACAGCTGAAATGCCATTTCACCTGGAACTTATTCAAGGAAGACAGTGTCTC AAGGGATCTAGAAGATAGAGTGTGTAACCAGATTGAATTTTTAAACACTGAGTTCAAAGCTACAATGTACAACTTGTTGGCCTACATAAA ACACCTAGATGGTAACAACGAGGCAGCCCTGGAATGCTTACGGCAAGCTGAAGAGTTAATCCAGCAAGAACATGCTGACCAAGCAGAAAT CAGAAGTCTAGTCACTTGGGGAAACTACGCCTGGGTCTACTATCACTTGGGCAGACTCTCAGATGCTCAGATTTATGTAGATAAGGTGAA ACAAACCTGCAAGAAATTTTCAAATCCATACAGTATTGAGTATTCTGAACTTGACTGTGAGGAAGGGTGGACACAACTGAAGTGTGGAAG AAATGAAAGGGCGAAGGTGTGTTTTGAGAAGGCTCTGGAAGAAAAGCCCAACAACCCAGAATTCTCCTCTGGACTGGCAATTGCGATGTA CCATCTGGATAATCACCCAGAGAAACAGTTCTCTACTGATGTTTTGAAGCAGGCCATTGAGCTGAGTCCTGATAACCAATACGTCAAGGT TCTCTTGGGCCTGAAACTGCAGAAGATGAATAAAGAAGCTGAAGGAGAGCAGTTTGTTGAAGAAGCCTTGGAAAAGTCTCCTTGCCAAAC AGATGTCCTCCGCAGTGCAGCCAAATTTTACAGAAGAAAAGGTGACCTAGACAAAGCTATTGAACTGTTTCAACGGGTGTTGGAATCCAC ACCAAACAATGGCTACCTCTATCACCAGATTGGGTGCTGCTACAAGGCAAAAGTAAGACAAATGCAGAATACAGGAGAATCTGAAGCTAG TGGAAATAAAGAGATGATTGAAGCACTAAAGCAATATGCTATGGACTATTCGAATAAAGCTCTTGAGAAGGGACTGAATCCTCTGAATGC ATACTCCGATCTCGCTGAGTTCCTGGAGACGGAATGTTATCAGACACCATTCAATAAGGAAGTCCCTGATGCTGAAAAGCAACAATCCCA TCAGCGCTACTGCAACCTTCAGAAATATAATGGGAAGTCTGAAGACACTGCTGTGCAACATGGTTTAGAGGGTTTGTCCATAAGCAAAAA ATCAACTGACAAGGAAGAGATCAAAGACCAACCACAGAATGTATCTGAAAATCTGCTTCCACAAAATGCACCAAATTATTGGTATCTTCA AGGATTAATTCATAAGCAGAATGGAGATCTGCTGCAAGCAGCCAAATGTTATGAGAAGGAACTGGGCCGCCTGCTAAGGGATGCCCCTTC AGGCATAGGCAGTATTTTCCTGTCAGCATCTGAGCTTGAGGATGGTAGTGAGGAAATGGGCCAGGGCGCAGTCAGCTCCAGTCCCAGAGA GCTCCTCTCTAACTCAGAGCAACTGAACTGAGACAGAGGAGGAAAACAGAGCATCAGAAGCCTGCAGTGGTGGTTGTGACGGGTAGGACG ATAGGAAGACAGGGGGCCCCAACCTGGGATTGCTGAGCAGGGAAGCTTTGCATGTTGCTCTAAGGTACATTTTTAAAGAGTTGTTTTTTG GCCGGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACGAGGTCTGGAGTTTGAGACCATCCTGG CTAACACAGTGAAATCCCGTCTCTACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGCTGGCACCTGTAGTCCCAGCTACTTGGGAGGC TGAGGCAGGAGAATGGCGTGAACCTGGAAGGAAGAGGTTGCAGTGAGCCAAGATTGCGCCCCTGCACTCCAGCCTGGGCAACAGAGCAAG ACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAAGAGTTGTTTTCTCATGTTCATTATAGTTCATTACAGTTACATAGTCCGAAGGTCTT ACAACTAATCACTGGTAGCAATAAATGCTTCAGGCCCACATGATGCTGATTAGTTCTCAGTTTTCATTCAGTTCACAATATAACCACCAT TCCTGCCCTCCCTGCCAAGGGTCATAAATGGTGACTGCCTAACAACAAAATTTGCAGTCTCATCTCATTTTCATCCAGACTTCTGGAACT CAAAGATTAACTTTTGACTAACCCTGGAATATCTCTTATCTCACTTATAGCTTCAGGCATGTATTTATATGTATTCTTGATAGCAATACC ATAATCAATGTGTATTCCTGATAGTAATGCTACAATAAATCCAAACATTTCAACTCTGTTAGAA >24030_24030_4_DPP6-IFIT3_DPP6_chr7_154461151_ENST00000377770_IFIT3_chr10_91098418_ENST00000371818_length(amino acids)=517AA_BP=29 MGILKVWTHQKSAMQNFSMQDGALKANSCEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKHL DGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNE RAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDV LRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYS DLAEFLETECYQTPFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYLQGL IHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN -------------------------------------------------------------- >24030_24030_5_DPP6-IFIT3_DPP6_chr7_154461151_ENST00000404039_IFIT3_chr10_91098418_ENST00000371811_length(transcript)=3468nt_BP=1157nt AGTTCAGACAGAAAACCTGGCGCGCGCGCGCGCACACACACACGCCTCCCCTGGCGTCGCCGCCCGGCCGGGTCCCTGCCCTTAGGGACC AGAGCGGCGACCGCTGCACCCCGCACCGCCTGCTGGAGGAGCCCCCGGAGCCGGGGCCGAGCCGCCGGCGTCCCCGAGTGCGCCCCCTGT GCGTGCCGCCGCGCTGTTGCTCGCAGTGTGCTGGCGCCGAGCTCGGTGGACACGCGCGCAGTCAGAGCTGCCTCTCGCCCTCGCTAGCTG GGCTCGCAGCCTCTTCCTCCCTCCCTGGCTCCTGGCTTTTTGTTTAAAGCAACACCCACCCTCCATCCAGGCTTTTTTTCTTTCTTTCTT TATTGGTAGCGGCCAAAAAGAGTTGATTGCTATTGGGATCCGCTGAGTAAAGACACGGGCAGGGGTGCGCGGAGGTGAGAAAACTGAAGA CCTGGAAGATTTTTTTTTCCTTCAAAAACCCGTTTCCATCCAGTCTTCAGCCAGTCCAGTCTACTTTAATCCTCACCAGGACAATGGATT AAGTTTCTCTTCCCTGGACCAGAAGTCGGGTTCGGACTTGGGGCAAAATGAAGGAAAAGGCCATGATCAAGACCGCTAAGATGCAGGGGA ACGTGATGGAGCTGGTGGGGAGTAACCCTCCGCAGAGGAATTGGAAAGGAATAGCAATTGCACTGCTTGTCATTCTGGTCATCTGCTCCT TGATCGTCACCTCGGTCATACTTCTGACACCAGCGGAAGATAATAGTCTGTCTCAAAAGAAGAAGGTCACTGTAGAAGATCTCTTCAGTG AAGACTTCAAAATTCATGACCCCGAGGCTAAGTGGATAAGTGATACAGAATTCATCTACAGAGAACAGAAAGGAACAGTGAGACTGTGGA ATGTTGAAACAAATACTTCTACTGTCTTAATAGAAGGCAAAAAAATTGAATCATTAAGAGCCATCAGATATGAAATATCTCCAGATAGAG AGTATGCACTTTTTTCATACAATGTGGAACCCATATATCAACACTCGTATACTGGATATTACGTCCTGAGCAAAATTCCTCATGGGGATC CTCAAAGTCTGGACCCACCAGAAGTCAGCAATGCAAAACTTCAGTATGCAGGATGGGGCCCTAAAGGCCAACAGCTGTGAGGTCACCAAG AATTCCCTGGAGAAAATCCTTCCACAGCTGAAATGCCATTTCACCTGGAACTTATTCAAGGAAGACAGTGTCTCAAGGGATCTAGAAGAT AGAGTGTGTAACCAGATTGAATTTTTAAACACTGAGTTCAAAGCTACAATGTACAACTTGTTGGCCTACATAAAACACCTAGATGGTAAC AACGAGGCAGCCCTGGAATGCTTACGGCAAGCTGAAGAGTTAATCCAGCAAGAACATGCTGACCAAGCAGAAATCAGAAGTCTAGTCACT TGGGGAAACTACGCCTGGGTCTACTATCACTTGGGCAGACTCTCAGATGCTCAGATTTATGTAGATAAGGTGAAACAAACCTGCAAGAAA TTTTCAAATCCATACAGTATTGAGTATTCTGAACTTGACTGTGAGGAAGGGTGGACACAACTGAAGTGTGGAAGAAATGAAAGGGCGAAG GTGTGTTTTGAGAAGGCTCTGGAAGAAAAGCCCAACAACCCAGAATTCTCCTCTGGACTGGCAATTGCGATGTACCATCTGGATAATCAC CCAGAGAAACAGTTCTCTACTGATGTTTTGAAGCAGGCCATTGAGCTGAGTCCTGATAACCAATACGTCAAGGTTCTCTTGGGCCTGAAA CTGCAGAAGATGAATAAAGAAGCTGAAGGAGAGCAGTTTGTTGAAGAAGCCTTGGAAAAGTCTCCTTGCCAAACAGATGTCCTCCGCAGT GCAGCCAAATTTTACAGAAGAAAAGGTGACCTAGACAAAGCTATTGAACTGTTTCAACGGGTGTTGGAATCCACACCAAACAATGGCTAC CTCTATCACCAGATTGGGTGCTGCTACAAGGCAAAAGTAAGACAAATGCAGAATACAGGAGAATCTGAAGCTAGTGGAAATAAAGAGATG ATTGAAGCACTAAAGCAATATGCTATGGACTATTCGAATAAAGCTCTTGAGAAGGGACTGAATCCTCTGAATGCATACTCCGATCTCGCT GAGTTCCTGGAGACGGAATGTTATCAGACACCATTCAATAAGGAAGTCCCTGATGCTGAAAAGCAACAATCCCATCAGCGCTACTGCAAC CTTCAGAAATATAATGGGAAGTCTGAAGACACTGCTGTGCAACATGGTTTAGAGGGTTTGTCCATAAGCAAAAAATCAACTGACAAGGAA GAGATCAAAGACCAACCACAGAATGTATCTGAAAATCTGCTTCCACAAAATGCACCAAATTATTGGTATCTTCAAGGATTAATTCATAAG CAGAATGGAGATCTGCTGCAAGCAGCCAAATGTTATGAGAAGGAACTGGGCCGCCTGCTAAGGGATGCCCCTTCAGGCATAGGCAGTATT TTCCTGTCAGCATCTGAGCTTGAGGATGGTAGTGAGGAAATGGGCCAGGGCGCAGTCAGCTCCAGTCCCAGAGAGCTCCTCTCTAACTCA GAGCAACTGAACTGAGACAGAGGAGGAAAACAGAGCATCAGAAGCCTGCAGTGGTGGTTGTGACGGGTAGGACGATAGGAAGACAGGGGG CCCCAACCTGGGATTGCTGAGCAGGGAAGCTTTGCATGTTGCTCTAAGGTACATTTTTAAAGAGTTGTTTTTTGGCCGGGCGCAGTGGCT CATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACGAGGTCTGGAGTTTGAGACCATCCTGGCTAACACAGTGAAATC CCGTCTCTACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGCTGGCACCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGG CGTGAACCTGGAAGGAAGAGGTTGCAGTGAGCCAAGATTGCGCCCCTGCACTCCAGCCTGGGCAACAGAGCAAGACTCCATCTCAAAAAA AAAAAAAAAAAAAAAAAAGAGTTGTTTTCTCATGTTCATTATAGTTCATTACAGTTACATAGTCCGAAGGTCTTACAACTAATCACTGGT AGCAATAAATGCTTCAGGCCCACATGATGCTGATTAGTTCTCAGTTTTCATTCAGTTCACAATATAACCACCATTCCTGCCCTCCCTGCC AAGGGTCATAAATGGTGACTGCCTAACAACAAAATTTGCAGTCTCATCTCATTTTCATCCAGACTTCTGGAACTCAAAGATTAACTTTTG ACTAACCCTGGAATATCTCTTATCTCACTTATAGCTTCAGGCATGTATTTATATGTATTCTTGATAGCAATACCATAATCAATGTGTATT CCTGATAGTAATGCTACAATAAATCCAAACATTTCAACTCTGTTAGAA >24030_24030_5_DPP6-IFIT3_DPP6_chr7_154461151_ENST00000404039_IFIT3_chr10_91098418_ENST00000371811_length(amino acids)=517AA_BP=29 MGILKVWTHQKSAMQNFSMQDGALKANSCEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKHL DGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNE RAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDV LRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYS DLAEFLETECYQTPFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYLQGL IHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN -------------------------------------------------------------- >24030_24030_6_DPP6-IFIT3_DPP6_chr7_154461151_ENST00000404039_IFIT3_chr10_91098418_ENST00000371818_length(transcript)=3468nt_BP=1157nt AGTTCAGACAGAAAACCTGGCGCGCGCGCGCGCACACACACACGCCTCCCCTGGCGTCGCCGCCCGGCCGGGTCCCTGCCCTTAGGGACC AGAGCGGCGACCGCTGCACCCCGCACCGCCTGCTGGAGGAGCCCCCGGAGCCGGGGCCGAGCCGCCGGCGTCCCCGAGTGCGCCCCCTGT GCGTGCCGCCGCGCTGTTGCTCGCAGTGTGCTGGCGCCGAGCTCGGTGGACACGCGCGCAGTCAGAGCTGCCTCTCGCCCTCGCTAGCTG GGCTCGCAGCCTCTTCCTCCCTCCCTGGCTCCTGGCTTTTTGTTTAAAGCAACACCCACCCTCCATCCAGGCTTTTTTTCTTTCTTTCTT TATTGGTAGCGGCCAAAAAGAGTTGATTGCTATTGGGATCCGCTGAGTAAAGACACGGGCAGGGGTGCGCGGAGGTGAGAAAACTGAAGA CCTGGAAGATTTTTTTTTCCTTCAAAAACCCGTTTCCATCCAGTCTTCAGCCAGTCCAGTCTACTTTAATCCTCACCAGGACAATGGATT AAGTTTCTCTTCCCTGGACCAGAAGTCGGGTTCGGACTTGGGGCAAAATGAAGGAAAAGGCCATGATCAAGACCGCTAAGATGCAGGGGA ACGTGATGGAGCTGGTGGGGAGTAACCCTCCGCAGAGGAATTGGAAAGGAATAGCAATTGCACTGCTTGTCATTCTGGTCATCTGCTCCT TGATCGTCACCTCGGTCATACTTCTGACACCAGCGGAAGATAATAGTCTGTCTCAAAAGAAGAAGGTCACTGTAGAAGATCTCTTCAGTG AAGACTTCAAAATTCATGACCCCGAGGCTAAGTGGATAAGTGATACAGAATTCATCTACAGAGAACAGAAAGGAACAGTGAGACTGTGGA ATGTTGAAACAAATACTTCTACTGTCTTAATAGAAGGCAAAAAAATTGAATCATTAAGAGCCATCAGATATGAAATATCTCCAGATAGAG AGTATGCACTTTTTTCATACAATGTGGAACCCATATATCAACACTCGTATACTGGATATTACGTCCTGAGCAAAATTCCTCATGGGGATC CTCAAAGTCTGGACCCACCAGAAGTCAGCAATGCAAAACTTCAGTATGCAGGATGGGGCCCTAAAGGCCAACAGCTGTGAGGTCACCAAG AATTCCCTGGAGAAAATCCTTCCACAGCTGAAATGCCATTTCACCTGGAACTTATTCAAGGAAGACAGTGTCTCAAGGGATCTAGAAGAT AGAGTGTGTAACCAGATTGAATTTTTAAACACTGAGTTCAAAGCTACAATGTACAACTTGTTGGCCTACATAAAACACCTAGATGGTAAC AACGAGGCAGCCCTGGAATGCTTACGGCAAGCTGAAGAGTTAATCCAGCAAGAACATGCTGACCAAGCAGAAATCAGAAGTCTAGTCACT TGGGGAAACTACGCCTGGGTCTACTATCACTTGGGCAGACTCTCAGATGCTCAGATTTATGTAGATAAGGTGAAACAAACCTGCAAGAAA TTTTCAAATCCATACAGTATTGAGTATTCTGAACTTGACTGTGAGGAAGGGTGGACACAACTGAAGTGTGGAAGAAATGAAAGGGCGAAG GTGTGTTTTGAGAAGGCTCTGGAAGAAAAGCCCAACAACCCAGAATTCTCCTCTGGACTGGCAATTGCGATGTACCATCTGGATAATCAC CCAGAGAAACAGTTCTCTACTGATGTTTTGAAGCAGGCCATTGAGCTGAGTCCTGATAACCAATACGTCAAGGTTCTCTTGGGCCTGAAA CTGCAGAAGATGAATAAAGAAGCTGAAGGAGAGCAGTTTGTTGAAGAAGCCTTGGAAAAGTCTCCTTGCCAAACAGATGTCCTCCGCAGT GCAGCCAAATTTTACAGAAGAAAAGGTGACCTAGACAAAGCTATTGAACTGTTTCAACGGGTGTTGGAATCCACACCAAACAATGGCTAC CTCTATCACCAGATTGGGTGCTGCTACAAGGCAAAAGTAAGACAAATGCAGAATACAGGAGAATCTGAAGCTAGTGGAAATAAAGAGATG ATTGAAGCACTAAAGCAATATGCTATGGACTATTCGAATAAAGCTCTTGAGAAGGGACTGAATCCTCTGAATGCATACTCCGATCTCGCT GAGTTCCTGGAGACGGAATGTTATCAGACACCATTCAATAAGGAAGTCCCTGATGCTGAAAAGCAACAATCCCATCAGCGCTACTGCAAC CTTCAGAAATATAATGGGAAGTCTGAAGACACTGCTGTGCAACATGGTTTAGAGGGTTTGTCCATAAGCAAAAAATCAACTGACAAGGAA GAGATCAAAGACCAACCACAGAATGTATCTGAAAATCTGCTTCCACAAAATGCACCAAATTATTGGTATCTTCAAGGATTAATTCATAAG CAGAATGGAGATCTGCTGCAAGCAGCCAAATGTTATGAGAAGGAACTGGGCCGCCTGCTAAGGGATGCCCCTTCAGGCATAGGCAGTATT TTCCTGTCAGCATCTGAGCTTGAGGATGGTAGTGAGGAAATGGGCCAGGGCGCAGTCAGCTCCAGTCCCAGAGAGCTCCTCTCTAACTCA GAGCAACTGAACTGAGACAGAGGAGGAAAACAGAGCATCAGAAGCCTGCAGTGGTGGTTGTGACGGGTAGGACGATAGGAAGACAGGGGG CCCCAACCTGGGATTGCTGAGCAGGGAAGCTTTGCATGTTGCTCTAAGGTACATTTTTAAAGAGTTGTTTTTTGGCCGGGCGCAGTGGCT CATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACGAGGTCTGGAGTTTGAGACCATCCTGGCTAACACAGTGAAATC CCGTCTCTACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGCTGGCACCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGG CGTGAACCTGGAAGGAAGAGGTTGCAGTGAGCCAAGATTGCGCCCCTGCACTCCAGCCTGGGCAACAGAGCAAGACTCCATCTCAAAAAA AAAAAAAAAAAAAAAAAAGAGTTGTTTTCTCATGTTCATTATAGTTCATTACAGTTACATAGTCCGAAGGTCTTACAACTAATCACTGGT AGCAATAAATGCTTCAGGCCCACATGATGCTGATTAGTTCTCAGTTTTCATTCAGTTCACAATATAACCACCATTCCTGCCCTCCCTGCC AAGGGTCATAAATGGTGACTGCCTAACAACAAAATTTGCAGTCTCATCTCATTTTCATCCAGACTTCTGGAACTCAAAGATTAACTTTTG ACTAACCCTGGAATATCTCTTATCTCACTTATAGCTTCAGGCATGTATTTATATGTATTCTTGATAGCAATACCATAATCAATGTGTATT CCTGATAGTAATGCTACAATAAATCCAAACATTTCAACTCTGTTAGAA >24030_24030_6_DPP6-IFIT3_DPP6_chr7_154461151_ENST00000404039_IFIT3_chr10_91098418_ENST00000371818_length(amino acids)=517AA_BP=29 MGILKVWTHQKSAMQNFSMQDGALKANSCEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKHL DGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNE RAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDV LRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYS DLAEFLETECYQTPFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYLQGL IHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN -------------------------------------------------------------- |
Top |
Fusion Gene PPI Analysis for DPP6-IFIT3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Related Drugs for DPP6-IFIT3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for DPP6-IFIT3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | DPP6 | C1510586 | Autism Spectrum Disorders | 2 | CTD_human |
| Hgene | DPP6 | C2751898 | Ventricular Fibrillation, Paroxysmal Familial, 1 | 2 | ORPHANET |
| Hgene | DPP6 | C4017668 | VENTRICULAR FIBRILLATION DURING MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO | 2 | ORPHANET |
| Hgene | DPP6 | C0002736 | Amyotrophic Lateral Sclerosis | 1 | CTD_human |
| Hgene | DPP6 | C0220693 | Microcephaly autosomal dominant | 1 | ORPHANET |
| Hgene | DPP6 | C0393554 | Amyotrophic Lateral Sclerosis With Dementia | 1 | CTD_human |
| Hgene | DPP6 | C0431350 | Primary microcephaly | 1 | GENOMICS_ENGLAND |
| Hgene | DPP6 | C0543859 | Amyotrophic Lateral Sclerosis, Guam Form | 1 | CTD_human |
| Hgene | DPP6 | C4225375 | MENTAL RETARDATION, AUTOSOMAL DOMINANT 33 | 1 | CTD_human;GENOMICS_ENGLAND;UNIPROT |
| Tgene | C0021400 | Influenza | 1 | CTD_human |
Copyright 2021-Present -The University of Texas Health Science Center at Houston (UTHealth)
Web File Viewing | Emergency Information |Campus Carry|Site Policies