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in Kim Lab

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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EFNA4-C20orf96 (FusionGDB2 ID:HG1945TG140680)

Fusion Gene Summary for EFNA4-C20orf96

check button Fusion gene summary
Fusion gene informationFusion gene name: EFNA4-C20orf96
Fusion gene ID: hg1945tg140680
HgeneTgene
Gene symbol

EFNA4

C20orf96

Gene ID

1945

140680

Gene nameephrin A4chromosome 20 open reading frame 96
SynonymsEFL4|EPLG4|LERK4dJ1103G7.2
Cytomap('EFNA4')('C20orf96')

1q21.3

20p13

Type of geneprotein-codingprotein-coding
Descriptionephrin-A4LERK-4eph-related receptor tyrosine kinase ligand 4ligand of eph-related kinase 4uncharacterized protein C20orf96
Modification date2020031320200313
UniProtAcc.

Q9NUD7

Ensembl transtripts involved in fusion geneENST00000359751, ENST00000368409, 
ENST00000427683, 
Fusion gene scores* DoF score3 X 2 X 3=184 X 5 X 4=80
# samples 46
** MAII scorelog2(4/18*10)=1.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(6/80*10)=-0.415037499278844
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EFNA4 [Title/Abstract] AND C20orf96 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEFNA4(155039916)-C20orf96(264722), # samples:3
Anticipated loss of major functional domain due to fusion event.EFNA4-C20orf96 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
EFNA4-C20orf96 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across EFNA4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across C20orf96 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E2-A109-01AEFNA4chr1

155039916

-C20orf96chr20

264722

-
ChimerDB4BRCATCGA-E2-A109-01AEFNA4chr1

155039916

+C20orf96chr20

264722

-


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Fusion Gene ORF analysis for EFNA4-C20orf96

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000359751ENST00000360321EFNA4chr1

155039916

+C20orf96chr20

264722

-
In-frameENST00000359751ENST00000382369EFNA4chr1

155039916

+C20orf96chr20

264722

-
In-frameENST00000359751ENST00000400269EFNA4chr1

155039916

+C20orf96chr20

264722

-
In-frameENST00000368409ENST00000360321EFNA4chr1

155039916

+C20orf96chr20

264722

-
In-frameENST00000368409ENST00000382369EFNA4chr1

155039916

+C20orf96chr20

264722

-
In-frameENST00000368409ENST00000400269EFNA4chr1

155039916

+C20orf96chr20

264722

-
In-frameENST00000427683ENST00000360321EFNA4chr1

155039916

+C20orf96chr20

264722

-
In-frameENST00000427683ENST00000382369EFNA4chr1

155039916

+C20orf96chr20

264722

-
In-frameENST00000427683ENST00000400269EFNA4chr1

155039916

+C20orf96chr20

264722

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000368409EFNA4chr1155039916+ENST00000382369C20orf96chr20264722-1811562931466457
ENST00000368409EFNA4chr1155039916+ENST00000360321C20orf96chr20264722-1811562931466457
ENST00000368409EFNA4chr1155039916+ENST00000400269C20orf96chr20264722-1511562931319408
ENST00000359751EFNA4chr1155039916+ENST00000382369C20orf96chr20264722-1805556871460457
ENST00000359751EFNA4chr1155039916+ENST00000360321C20orf96chr20264722-1805556871460457
ENST00000359751EFNA4chr1155039916+ENST00000400269C20orf96chr20264722-1505556871313408
ENST00000427683EFNA4chr1155039916+ENST00000382369C20orf96chr20264722-1781532631436457
ENST00000427683EFNA4chr1155039916+ENST00000360321C20orf96chr20264722-1781532631436457
ENST00000427683EFNA4chr1155039916+ENST00000400269C20orf96chr20264722-1481532631289408

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000368409ENST00000382369EFNA4chr1155039916+C20orf96chr20264722-0.0105840770.989416
ENST00000368409ENST00000360321EFNA4chr1155039916+C20orf96chr20264722-0.0105840770.989416
ENST00000368409ENST00000400269EFNA4chr1155039916+C20orf96chr20264722-0.0266132350.97338676
ENST00000359751ENST00000382369EFNA4chr1155039916+C20orf96chr20264722-0.01016150.9898385
ENST00000359751ENST00000360321EFNA4chr1155039916+C20orf96chr20264722-0.01016150.9898385
ENST00000359751ENST00000400269EFNA4chr1155039916+C20orf96chr20264722-0.025535780.97446424
ENST00000427683ENST00000382369EFNA4chr1155039916+C20orf96chr20264722-0.0114182470.9885817
ENST00000427683ENST00000360321EFNA4chr1155039916+C20orf96chr20264722-0.0114182470.9885817
ENST00000427683ENST00000400269EFNA4chr1155039916+C20orf96chr20264722-0.0235475860.9764524

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Fusion Genomic Features for EFNA4-C20orf96


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for EFNA4-C20orf96


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:155039916/chr20:264722)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.C20orf96

Q9NUD7

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEFNA4chr1:155039916chr20:264722ENST00000359751+3426_155156194.0DomainEphrin RBD
HgeneEFNA4chr1:155039916chr20:264722ENST00000368409+3426_155156202.0DomainEphrin RBD
HgeneEFNA4chr1:155039916chr20:264722ENST00000427683+3426_155156208.0DomainEphrin RBD
TgeneC20orf96chr1:155039916chr20:264722ENST00000360321211109_32962364.0Coiled coilOntology_term=ECO:0000255
TgeneC20orf96chr1:155039916chr20:264722ENST00000360321211264_26862364.0Compositional biasNote=Poly-Lys

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for EFNA4-C20orf96


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>25381_25381_1_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000359751_C20orf96_chr20_264722_ENST00000360321_length(transcript)=1805nt_BP=556nt
CTTCCCTCTTCACTTTGTACCTTTCTCTCCTCGACTGTGAAGCGGGCCGGGACCTGCCAGGCCAGACCAAACCGGACCTCGGGGGCGATG
CGGCTGCTGCCCCTGCTGCGGACTGTCCTCTGGGCCGCGTTCCTCGGCTCCCCTCTGCGCGGGGGCTCCAGCCTCCGCCACGTAGTCTAC
TGGAACTCCAGTAACCCCAGGTTGCTTCGAGGAGACGCCGTGGTGGAGCTGGGCCTCAACGATTACCTAGACATTGTCTGCCCCCACTAC
GAAGGCCCAGGGCCCCCTGAGGGCCCCGAGACGTTTGCTTTGTACATGGTGGACTGGCCAGGCTATGAGTCCTGCCAGGCAGAGGGCCCC
CGGGCCTACAAGCGCTGGGTGTGCTCCCTGCCCTTTGGCCATGTTCAATTCTCAGAGAAGATTCAGCGCTTCACACCCTTCTCCCTCGGC
TTTGAGTTCTTACCTGGAGAGACTTACTACTACATCTCGGTGCCCACTCCAGAGAGTTCTGGCCAGTGCTTGAGGCTCCAGGTGTCTGTC
TGCTGCAAGGAGAGGATGTTTCACTTCAAGCCCACTACGGTGGTGACAAGCTGCCAGCCGAAGAATCCAAGAGAACTACATAGAAGGCGG
AAGTTGGACCCTGGGAAGATGCATGCCAAAATCTGGTTAATGAAGACCTCGCTCAGGAGCGGGAGGGCCGCTCTGCGAGAGCTCCGAAGC
CGTGAGAACTTCCTCAGCAAGCTCAACCGGGAGCTGATCGAGACCATCCAGGAGATGGAGAACAGCACGACCCTGCACGTGCGGGCCCTG
CTGCAGCAGCAGGACACCCTGGCGACCATCATCGACATCTTGGAGTACTCAAACAAGAAGAGGCTGCAGCAATTGAAATCTGAGCTTCAG
GAGTGGGAAGAAAAGAAGAAATGCAAGATGAGCTATCTTGAGCAGCAGGCAGAGCAGCTGAATGCCAAGATTGAGAAGACCCAGGAGGAA
GTGAACTTCCTGAGCACTTACATGGACCATGAGTATTCCATCAAGTCTGTCCAGATCTCCACTCTTATGCGCCAGCTGCAGCAGGTTAAG
GACAGCCAGCAGGATGAGCTGGATGACCTCGGTGAGATGCGCAGAAAGGTCCTGGAATCCTTGTCTGACAAGATTCAGAAGAAGAAGAAA
AAAATTCTGAGTTCTGTGGTGGCGGAAACCCAGCGTCCCTATGAAGAGGCTCTCCTACAGAAGATGTGGGAAAGCCAGGACTTCCTGAAA
TGCATGCAAAGGTTCAGAGAAATTATTGACCAGTTTGAGGAGAACATGCCTGTATTAAGGGCCGAGGTGGAAGAGCTCCAAGCCCAGACC
CGGGAACCCCGAGAGGTCATATTTGAGGATGTTCTGCTTCGGAGACCCAAGTGCACCCCAGACATGGATGTCATCCTCAACATTCCTGTG
GAAGAGCCACTACCCTTCTAGATGGCAGTGCCATGGGCCGCCCTCCCCTCCTGCTCTCTTCCCAGCACCTGGAGCCTTGGATCATTTACT
TCCAGGACCGGATCTCCATTCAGACCCTGATCTACAGTCTCCCTGCTCCCTCTGCCCTTCCTCCCTCTTTCTTTCCCTCCCTCCCTCCCT
CCCTTCTTCCCCCCTTCCCTTCCCTCCTCCTTCCTTCCTCCTCTCCCTCCCTCCCTCCTTTCTTTCTTCCTGTGGTTTTTTCCTCTCTTC
TTCCCTTCTTTCTGGTTGGTGCTGCTGGGCCAGGTGGGAATTTCTGATTAAATCTGCTATTCCTTTTTTACCAATAAAGCTGGATTTACA

>25381_25381_1_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000359751_C20orf96_chr20_264722_ENST00000360321_length(amino acids)=457AA_BP=157
MRLLPLLRTVLWAAFLGSPLRGGSSLRHVVYWNSSNPRLLRGDAVVELGLNDYLDIVCPHYEGPGPPEGPETFALYMVDWPGYESCQAEG
PRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYISVPTPESSGQCLRLQVSVCCKERMFHFKPTTVVTSCQPKNPRELHRR
RKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSEL
QEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKK
KKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREIIDQFEENMPVLRAEVEELQAQTREPREVIFEDVLLRRPKCTPDMDVILNIP

--------------------------------------------------------------
>25381_25381_2_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000359751_C20orf96_chr20_264722_ENST00000382369_length(transcript)=1805nt_BP=556nt
CTTCCCTCTTCACTTTGTACCTTTCTCTCCTCGACTGTGAAGCGGGCCGGGACCTGCCAGGCCAGACCAAACCGGACCTCGGGGGCGATG
CGGCTGCTGCCCCTGCTGCGGACTGTCCTCTGGGCCGCGTTCCTCGGCTCCCCTCTGCGCGGGGGCTCCAGCCTCCGCCACGTAGTCTAC
TGGAACTCCAGTAACCCCAGGTTGCTTCGAGGAGACGCCGTGGTGGAGCTGGGCCTCAACGATTACCTAGACATTGTCTGCCCCCACTAC
GAAGGCCCAGGGCCCCCTGAGGGCCCCGAGACGTTTGCTTTGTACATGGTGGACTGGCCAGGCTATGAGTCCTGCCAGGCAGAGGGCCCC
CGGGCCTACAAGCGCTGGGTGTGCTCCCTGCCCTTTGGCCATGTTCAATTCTCAGAGAAGATTCAGCGCTTCACACCCTTCTCCCTCGGC
TTTGAGTTCTTACCTGGAGAGACTTACTACTACATCTCGGTGCCCACTCCAGAGAGTTCTGGCCAGTGCTTGAGGCTCCAGGTGTCTGTC
TGCTGCAAGGAGAGGATGTTTCACTTCAAGCCCACTACGGTGGTGACAAGCTGCCAGCCGAAGAATCCAAGAGAACTACATAGAAGGCGG
AAGTTGGACCCTGGGAAGATGCATGCCAAAATCTGGTTAATGAAGACCTCGCTCAGGAGCGGGAGGGCCGCTCTGCGAGAGCTCCGAAGC
CGTGAGAACTTCCTCAGCAAGCTCAACCGGGAGCTGATCGAGACCATCCAGGAGATGGAGAACAGCACGACCCTGCACGTGCGGGCCCTG
CTGCAGCAGCAGGACACCCTGGCGACCATCATCGACATCTTGGAGTACTCAAACAAGAAGAGGCTGCAGCAATTGAAATCTGAGCTTCAG
GAGTGGGAAGAAAAGAAGAAATGCAAGATGAGCTATCTTGAGCAGCAGGCAGAGCAGCTGAATGCCAAGATTGAGAAGACCCAGGAGGAA
GTGAACTTCCTGAGCACTTACATGGACCATGAGTATTCCATCAAGTCTGTCCAGATCTCCACTCTTATGCGCCAGCTGCAGCAGGTTAAG
GACAGCCAGCAGGATGAGCTGGATGACCTCGGTGAGATGCGCAGAAAGGTCCTGGAATCCTTGTCTGACAAGATTCAGAAGAAGAAGAAA
AAAATTCTGAGTTCTGTGGTGGCGGAAACCCAGCGTCCCTATGAAGAGGCTCTCCTACAGAAGATGTGGGAAAGCCAGGACTTCCTGAAA
TGCATGCAAAGGTTCAGAGAAATTATTGACCAGTTTGAGGAGAACATGCCTGTATTAAGGGCCGAGGTGGAAGAGCTCCAAGCCCAGACC
CGGGAACCCCGAGAGGTCATATTTGAGGATGTTCTGCTTCGGAGACCCAAGTGCACCCCAGACATGGATGTCATCCTCAACATTCCTGTG
GAAGAGCCACTACCCTTCTAGATGGCAGTGCCATGGGCCGCCCTCCCCTCCTGCTCTCTTCCCAGCACCTGGAGCCTTGGATCATTTACT
TCCAGGACCGGATCTCCATTCAGACCCTGATCTACAGTCTCCCTGCTCCCTCTGCCCTTCCTCCCTCTTTCTTTCCCTCCCTCCCTCCCT
CCCTTCTTCCCCCCTTCCCTTCCCTCCTCCTTCCTTCCTCCTCTCCCTCCCTCCCTCCTTTCTTTCTTCCTGTGGTTTTTTCCTCTCTTC
TTCCCTTCTTTCTGGTTGGTGCTGCTGGGCCAGGTGGGAATTTCTGATTAAATCTGCTATTCCTTTTTTACCAATAAAGCTGGATTTACA

>25381_25381_2_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000359751_C20orf96_chr20_264722_ENST00000382369_length(amino acids)=457AA_BP=157
MRLLPLLRTVLWAAFLGSPLRGGSSLRHVVYWNSSNPRLLRGDAVVELGLNDYLDIVCPHYEGPGPPEGPETFALYMVDWPGYESCQAEG
PRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYISVPTPESSGQCLRLQVSVCCKERMFHFKPTTVVTSCQPKNPRELHRR
RKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSEL
QEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKK
KKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREIIDQFEENMPVLRAEVEELQAQTREPREVIFEDVLLRRPKCTPDMDVILNIP

--------------------------------------------------------------
>25381_25381_3_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000359751_C20orf96_chr20_264722_ENST00000400269_length(transcript)=1505nt_BP=556nt
CTTCCCTCTTCACTTTGTACCTTTCTCTCCTCGACTGTGAAGCGGGCCGGGACCTGCCAGGCCAGACCAAACCGGACCTCGGGGGCGATG
CGGCTGCTGCCCCTGCTGCGGACTGTCCTCTGGGCCGCGTTCCTCGGCTCCCCTCTGCGCGGGGGCTCCAGCCTCCGCCACGTAGTCTAC
TGGAACTCCAGTAACCCCAGGTTGCTTCGAGGAGACGCCGTGGTGGAGCTGGGCCTCAACGATTACCTAGACATTGTCTGCCCCCACTAC
GAAGGCCCAGGGCCCCCTGAGGGCCCCGAGACGTTTGCTTTGTACATGGTGGACTGGCCAGGCTATGAGTCCTGCCAGGCAGAGGGCCCC
CGGGCCTACAAGCGCTGGGTGTGCTCCCTGCCCTTTGGCCATGTTCAATTCTCAGAGAAGATTCAGCGCTTCACACCCTTCTCCCTCGGC
TTTGAGTTCTTACCTGGAGAGACTTACTACTACATCTCGGTGCCCACTCCAGAGAGTTCTGGCCAGTGCTTGAGGCTCCAGGTGTCTGTC
TGCTGCAAGGAGAGGATGTTTCACTTCAAGCCCACTACGGTGGTGACAAGCTGCCAGCCGAAGAATCCAAGAGAACTACATAGAAGGCGG
AAGTTGGACCCTGGGAAGATGCATGCCAAAATCTGGTTAATGAAGACCTCGCTCAGGAGCGGGAGGGCCGCTCTGCGAGAGCTCCGAAGC
CGTGAGAACTTCCTCAGCAAGCTCAACCGGGAGCTGATCGAGACCATCCAGGAGATGGAGAACAGCACGACCCTGCACGTGCGGGCCCTG
CTGCAGCAGCAGGACACCCTGGCGACCATCATCGACATCTTGGAGTACTCAAACAAGAAGAGGCTGCAGCAATTGAAATCTGAGCTTCAG
GAGTGGGAAGAAAAGAAGAAATGCAAGATGAGCTATCTTGAGCAGCAGGCAGAGCAGCTGAATGCCAAGATTGAGAAGACCCAGGAGGAA
GTGAACTTCCTGAGCACTTACATGGACCATGAGTATTCCATCAAGTCTGTCCAGATCTCCACTCTTATGCGCCAGCTGCAGCAGGTTAAG
GACAGCCAGCAGGATGAGCTGGATGACCTCGGTGAGATGCGCAGAAAGGTCCTGGAATCCTTGTCTGACAAGATTCAGAAGAAGAAGAAA
AAAATTCTGAGTTCTGTGGTGGCGGAAACCCAGCGTCCCTATGAAGAGGCTCTCCTACAGAAGATGTGGGAAAGCCAGGACTTCCTGAAA
TGCATGCAAAGGTTCAGAGAAGTGCGTGGGCAAGGAAGGTGGTGGTCCCTGTAGGGAAGCAGTGGATGGGCAGTCCCCACGGCCTGTGGG
AATGAGTCAGGCTTCTCCTGATCTGGCGCTCAGGAGGTCTCTGACTCTGGTGTTGGCCTCCCTCCTTGCCGGTGCCATTACTGTCACTTG

>25381_25381_3_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000359751_C20orf96_chr20_264722_ENST00000400269_length(amino acids)=408AA_BP=157
MRLLPLLRTVLWAAFLGSPLRGGSSLRHVVYWNSSNPRLLRGDAVVELGLNDYLDIVCPHYEGPGPPEGPETFALYMVDWPGYESCQAEG
PRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYISVPTPESSGQCLRLQVSVCCKERMFHFKPTTVVTSCQPKNPRELHRR
RKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSEL
QEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKK

--------------------------------------------------------------
>25381_25381_4_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000368409_C20orf96_chr20_264722_ENST00000360321_length(transcript)=1811nt_BP=562nt
CCGCAACTTCCCTCTTCACTTTGTACCTTTCTCTCCTCGACTGTGAAGCGGGCCGGGACCTGCCAGGCCAGACCAAACCGGACCTCGGGG
GCGATGCGGCTGCTGCCCCTGCTGCGGACTGTCCTCTGGGCCGCGTTCCTCGGCTCCCCTCTGCGCGGGGGCTCCAGCCTCCGCCACGTA
GTCTACTGGAACTCCAGTAACCCCAGGTTGCTTCGAGGAGACGCCGTGGTGGAGCTGGGCCTCAACGATTACCTAGACATTGTCTGCCCC
CACTACGAAGGCCCAGGGCCCCCTGAGGGCCCCGAGACGTTTGCTTTGTACATGGTGGACTGGCCAGGCTATGAGTCCTGCCAGGCAGAG
GGCCCCCGGGCCTACAAGCGCTGGGTGTGCTCCCTGCCCTTTGGCCATGTTCAATTCTCAGAGAAGATTCAGCGCTTCACACCCTTCTCC
CTCGGCTTTGAGTTCTTACCTGGAGAGACTTACTACTACATCTCGGTGCCCACTCCAGAGAGTTCTGGCCAGTGCTTGAGGCTCCAGGTG
TCTGTCTGCTGCAAGGAGAGGATGTTTCACTTCAAGCCCACTACGGTGGTGACAAGCTGCCAGCCGAAGAATCCAAGAGAACTACATAGA
AGGCGGAAGTTGGACCCTGGGAAGATGCATGCCAAAATCTGGTTAATGAAGACCTCGCTCAGGAGCGGGAGGGCCGCTCTGCGAGAGCTC
CGAAGCCGTGAGAACTTCCTCAGCAAGCTCAACCGGGAGCTGATCGAGACCATCCAGGAGATGGAGAACAGCACGACCCTGCACGTGCGG
GCCCTGCTGCAGCAGCAGGACACCCTGGCGACCATCATCGACATCTTGGAGTACTCAAACAAGAAGAGGCTGCAGCAATTGAAATCTGAG
CTTCAGGAGTGGGAAGAAAAGAAGAAATGCAAGATGAGCTATCTTGAGCAGCAGGCAGAGCAGCTGAATGCCAAGATTGAGAAGACCCAG
GAGGAAGTGAACTTCCTGAGCACTTACATGGACCATGAGTATTCCATCAAGTCTGTCCAGATCTCCACTCTTATGCGCCAGCTGCAGCAG
GTTAAGGACAGCCAGCAGGATGAGCTGGATGACCTCGGTGAGATGCGCAGAAAGGTCCTGGAATCCTTGTCTGACAAGATTCAGAAGAAG
AAGAAAAAAATTCTGAGTTCTGTGGTGGCGGAAACCCAGCGTCCCTATGAAGAGGCTCTCCTACAGAAGATGTGGGAAAGCCAGGACTTC
CTGAAATGCATGCAAAGGTTCAGAGAAATTATTGACCAGTTTGAGGAGAACATGCCTGTATTAAGGGCCGAGGTGGAAGAGCTCCAAGCC
CAGACCCGGGAACCCCGAGAGGTCATATTTGAGGATGTTCTGCTTCGGAGACCCAAGTGCACCCCAGACATGGATGTCATCCTCAACATT
CCTGTGGAAGAGCCACTACCCTTCTAGATGGCAGTGCCATGGGCCGCCCTCCCCTCCTGCTCTCTTCCCAGCACCTGGAGCCTTGGATCA
TTTACTTCCAGGACCGGATCTCCATTCAGACCCTGATCTACAGTCTCCCTGCTCCCTCTGCCCTTCCTCCCTCTTTCTTTCCCTCCCTCC
CTCCCTCCCTTCTTCCCCCCTTCCCTTCCCTCCTCCTTCCTTCCTCCTCTCCCTCCCTCCCTCCTTTCTTTCTTCCTGTGGTTTTTTCCT
CTCTTCTTCCCTTCTTTCTGGTTGGTGCTGCTGGGCCAGGTGGGAATTTCTGATTAAATCTGCTATTCCTTTTTTACCAATAAAGCTGGA

>25381_25381_4_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000368409_C20orf96_chr20_264722_ENST00000360321_length(amino acids)=457AA_BP=157
MRLLPLLRTVLWAAFLGSPLRGGSSLRHVVYWNSSNPRLLRGDAVVELGLNDYLDIVCPHYEGPGPPEGPETFALYMVDWPGYESCQAEG
PRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYISVPTPESSGQCLRLQVSVCCKERMFHFKPTTVVTSCQPKNPRELHRR
RKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSEL
QEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKK
KKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREIIDQFEENMPVLRAEVEELQAQTREPREVIFEDVLLRRPKCTPDMDVILNIP

--------------------------------------------------------------
>25381_25381_5_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000368409_C20orf96_chr20_264722_ENST00000382369_length(transcript)=1811nt_BP=562nt
CCGCAACTTCCCTCTTCACTTTGTACCTTTCTCTCCTCGACTGTGAAGCGGGCCGGGACCTGCCAGGCCAGACCAAACCGGACCTCGGGG
GCGATGCGGCTGCTGCCCCTGCTGCGGACTGTCCTCTGGGCCGCGTTCCTCGGCTCCCCTCTGCGCGGGGGCTCCAGCCTCCGCCACGTA
GTCTACTGGAACTCCAGTAACCCCAGGTTGCTTCGAGGAGACGCCGTGGTGGAGCTGGGCCTCAACGATTACCTAGACATTGTCTGCCCC
CACTACGAAGGCCCAGGGCCCCCTGAGGGCCCCGAGACGTTTGCTTTGTACATGGTGGACTGGCCAGGCTATGAGTCCTGCCAGGCAGAG
GGCCCCCGGGCCTACAAGCGCTGGGTGTGCTCCCTGCCCTTTGGCCATGTTCAATTCTCAGAGAAGATTCAGCGCTTCACACCCTTCTCC
CTCGGCTTTGAGTTCTTACCTGGAGAGACTTACTACTACATCTCGGTGCCCACTCCAGAGAGTTCTGGCCAGTGCTTGAGGCTCCAGGTG
TCTGTCTGCTGCAAGGAGAGGATGTTTCACTTCAAGCCCACTACGGTGGTGACAAGCTGCCAGCCGAAGAATCCAAGAGAACTACATAGA
AGGCGGAAGTTGGACCCTGGGAAGATGCATGCCAAAATCTGGTTAATGAAGACCTCGCTCAGGAGCGGGAGGGCCGCTCTGCGAGAGCTC
CGAAGCCGTGAGAACTTCCTCAGCAAGCTCAACCGGGAGCTGATCGAGACCATCCAGGAGATGGAGAACAGCACGACCCTGCACGTGCGG
GCCCTGCTGCAGCAGCAGGACACCCTGGCGACCATCATCGACATCTTGGAGTACTCAAACAAGAAGAGGCTGCAGCAATTGAAATCTGAG
CTTCAGGAGTGGGAAGAAAAGAAGAAATGCAAGATGAGCTATCTTGAGCAGCAGGCAGAGCAGCTGAATGCCAAGATTGAGAAGACCCAG
GAGGAAGTGAACTTCCTGAGCACTTACATGGACCATGAGTATTCCATCAAGTCTGTCCAGATCTCCACTCTTATGCGCCAGCTGCAGCAG
GTTAAGGACAGCCAGCAGGATGAGCTGGATGACCTCGGTGAGATGCGCAGAAAGGTCCTGGAATCCTTGTCTGACAAGATTCAGAAGAAG
AAGAAAAAAATTCTGAGTTCTGTGGTGGCGGAAACCCAGCGTCCCTATGAAGAGGCTCTCCTACAGAAGATGTGGGAAAGCCAGGACTTC
CTGAAATGCATGCAAAGGTTCAGAGAAATTATTGACCAGTTTGAGGAGAACATGCCTGTATTAAGGGCCGAGGTGGAAGAGCTCCAAGCC
CAGACCCGGGAACCCCGAGAGGTCATATTTGAGGATGTTCTGCTTCGGAGACCCAAGTGCACCCCAGACATGGATGTCATCCTCAACATT
CCTGTGGAAGAGCCACTACCCTTCTAGATGGCAGTGCCATGGGCCGCCCTCCCCTCCTGCTCTCTTCCCAGCACCTGGAGCCTTGGATCA
TTTACTTCCAGGACCGGATCTCCATTCAGACCCTGATCTACAGTCTCCCTGCTCCCTCTGCCCTTCCTCCCTCTTTCTTTCCCTCCCTCC
CTCCCTCCCTTCTTCCCCCCTTCCCTTCCCTCCTCCTTCCTTCCTCCTCTCCCTCCCTCCCTCCTTTCTTTCTTCCTGTGGTTTTTTCCT
CTCTTCTTCCCTTCTTTCTGGTTGGTGCTGCTGGGCCAGGTGGGAATTTCTGATTAAATCTGCTATTCCTTTTTTACCAATAAAGCTGGA

>25381_25381_5_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000368409_C20orf96_chr20_264722_ENST00000382369_length(amino acids)=457AA_BP=157
MRLLPLLRTVLWAAFLGSPLRGGSSLRHVVYWNSSNPRLLRGDAVVELGLNDYLDIVCPHYEGPGPPEGPETFALYMVDWPGYESCQAEG
PRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYISVPTPESSGQCLRLQVSVCCKERMFHFKPTTVVTSCQPKNPRELHRR
RKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSEL
QEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKK
KKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREIIDQFEENMPVLRAEVEELQAQTREPREVIFEDVLLRRPKCTPDMDVILNIP

--------------------------------------------------------------
>25381_25381_6_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000368409_C20orf96_chr20_264722_ENST00000400269_length(transcript)=1511nt_BP=562nt
CCGCAACTTCCCTCTTCACTTTGTACCTTTCTCTCCTCGACTGTGAAGCGGGCCGGGACCTGCCAGGCCAGACCAAACCGGACCTCGGGG
GCGATGCGGCTGCTGCCCCTGCTGCGGACTGTCCTCTGGGCCGCGTTCCTCGGCTCCCCTCTGCGCGGGGGCTCCAGCCTCCGCCACGTA
GTCTACTGGAACTCCAGTAACCCCAGGTTGCTTCGAGGAGACGCCGTGGTGGAGCTGGGCCTCAACGATTACCTAGACATTGTCTGCCCC
CACTACGAAGGCCCAGGGCCCCCTGAGGGCCCCGAGACGTTTGCTTTGTACATGGTGGACTGGCCAGGCTATGAGTCCTGCCAGGCAGAG
GGCCCCCGGGCCTACAAGCGCTGGGTGTGCTCCCTGCCCTTTGGCCATGTTCAATTCTCAGAGAAGATTCAGCGCTTCACACCCTTCTCC
CTCGGCTTTGAGTTCTTACCTGGAGAGACTTACTACTACATCTCGGTGCCCACTCCAGAGAGTTCTGGCCAGTGCTTGAGGCTCCAGGTG
TCTGTCTGCTGCAAGGAGAGGATGTTTCACTTCAAGCCCACTACGGTGGTGACAAGCTGCCAGCCGAAGAATCCAAGAGAACTACATAGA
AGGCGGAAGTTGGACCCTGGGAAGATGCATGCCAAAATCTGGTTAATGAAGACCTCGCTCAGGAGCGGGAGGGCCGCTCTGCGAGAGCTC
CGAAGCCGTGAGAACTTCCTCAGCAAGCTCAACCGGGAGCTGATCGAGACCATCCAGGAGATGGAGAACAGCACGACCCTGCACGTGCGG
GCCCTGCTGCAGCAGCAGGACACCCTGGCGACCATCATCGACATCTTGGAGTACTCAAACAAGAAGAGGCTGCAGCAATTGAAATCTGAG
CTTCAGGAGTGGGAAGAAAAGAAGAAATGCAAGATGAGCTATCTTGAGCAGCAGGCAGAGCAGCTGAATGCCAAGATTGAGAAGACCCAG
GAGGAAGTGAACTTCCTGAGCACTTACATGGACCATGAGTATTCCATCAAGTCTGTCCAGATCTCCACTCTTATGCGCCAGCTGCAGCAG
GTTAAGGACAGCCAGCAGGATGAGCTGGATGACCTCGGTGAGATGCGCAGAAAGGTCCTGGAATCCTTGTCTGACAAGATTCAGAAGAAG
AAGAAAAAAATTCTGAGTTCTGTGGTGGCGGAAACCCAGCGTCCCTATGAAGAGGCTCTCCTACAGAAGATGTGGGAAAGCCAGGACTTC
CTGAAATGCATGCAAAGGTTCAGAGAAGTGCGTGGGCAAGGAAGGTGGTGGTCCCTGTAGGGAAGCAGTGGATGGGCAGTCCCCACGGCC
TGTGGGAATGAGTCAGGCTTCTCCTGATCTGGCGCTCAGGAGGTCTCTGACTCTGGTGTTGGCCTCCCTCCTTGCCGGTGCCATTACTGT

>25381_25381_6_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000368409_C20orf96_chr20_264722_ENST00000400269_length(amino acids)=408AA_BP=157
MRLLPLLRTVLWAAFLGSPLRGGSSLRHVVYWNSSNPRLLRGDAVVELGLNDYLDIVCPHYEGPGPPEGPETFALYMVDWPGYESCQAEG
PRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYISVPTPESSGQCLRLQVSVCCKERMFHFKPTTVVTSCQPKNPRELHRR
RKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSEL
QEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKK

--------------------------------------------------------------
>25381_25381_7_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000427683_C20orf96_chr20_264722_ENST00000360321_length(transcript)=1781nt_BP=532nt
CTCTCCTCGACTGTGAAGCGGGCCGGGACCTGCCAGGCCAGACCAAACCGGACCTCGGGGGCGATGCGGCTGCTGCCCCTGCTGCGGACT
GTCCTCTGGGCCGCGTTCCTCGGCTCCCCTCTGCGCGGGGGCTCCAGCCTCCGCCACGTAGTCTACTGGAACTCCAGTAACCCCAGGTTG
CTTCGAGGAGACGCCGTGGTGGAGCTGGGCCTCAACGATTACCTAGACATTGTCTGCCCCCACTACGAAGGCCCAGGGCCCCCTGAGGGC
CCCGAGACGTTTGCTTTGTACATGGTGGACTGGCCAGGCTATGAGTCCTGCCAGGCAGAGGGCCCCCGGGCCTACAAGCGCTGGGTGTGC
TCCCTGCCCTTTGGCCATGTTCAATTCTCAGAGAAGATTCAGCGCTTCACACCCTTCTCCCTCGGCTTTGAGTTCTTACCTGGAGAGACT
TACTACTACATCTCGGTGCCCACTCCAGAGAGTTCTGGCCAGTGCTTGAGGCTCCAGGTGTCTGTCTGCTGCAAGGAGAGGATGTTTCAC
TTCAAGCCCACTACGGTGGTGACAAGCTGCCAGCCGAAGAATCCAAGAGAACTACATAGAAGGCGGAAGTTGGACCCTGGGAAGATGCAT
GCCAAAATCTGGTTAATGAAGACCTCGCTCAGGAGCGGGAGGGCCGCTCTGCGAGAGCTCCGAAGCCGTGAGAACTTCCTCAGCAAGCTC
AACCGGGAGCTGATCGAGACCATCCAGGAGATGGAGAACAGCACGACCCTGCACGTGCGGGCCCTGCTGCAGCAGCAGGACACCCTGGCG
ACCATCATCGACATCTTGGAGTACTCAAACAAGAAGAGGCTGCAGCAATTGAAATCTGAGCTTCAGGAGTGGGAAGAAAAGAAGAAATGC
AAGATGAGCTATCTTGAGCAGCAGGCAGAGCAGCTGAATGCCAAGATTGAGAAGACCCAGGAGGAAGTGAACTTCCTGAGCACTTACATG
GACCATGAGTATTCCATCAAGTCTGTCCAGATCTCCACTCTTATGCGCCAGCTGCAGCAGGTTAAGGACAGCCAGCAGGATGAGCTGGAT
GACCTCGGTGAGATGCGCAGAAAGGTCCTGGAATCCTTGTCTGACAAGATTCAGAAGAAGAAGAAAAAAATTCTGAGTTCTGTGGTGGCG
GAAACCCAGCGTCCCTATGAAGAGGCTCTCCTACAGAAGATGTGGGAAAGCCAGGACTTCCTGAAATGCATGCAAAGGTTCAGAGAAATT
ATTGACCAGTTTGAGGAGAACATGCCTGTATTAAGGGCCGAGGTGGAAGAGCTCCAAGCCCAGACCCGGGAACCCCGAGAGGTCATATTT
GAGGATGTTCTGCTTCGGAGACCCAAGTGCACCCCAGACATGGATGTCATCCTCAACATTCCTGTGGAAGAGCCACTACCCTTCTAGATG
GCAGTGCCATGGGCCGCCCTCCCCTCCTGCTCTCTTCCCAGCACCTGGAGCCTTGGATCATTTACTTCCAGGACCGGATCTCCATTCAGA
CCCTGATCTACAGTCTCCCTGCTCCCTCTGCCCTTCCTCCCTCTTTCTTTCCCTCCCTCCCTCCCTCCCTTCTTCCCCCCTTCCCTTCCC
TCCTCCTTCCTTCCTCCTCTCCCTCCCTCCCTCCTTTCTTTCTTCCTGTGGTTTTTTCCTCTCTTCTTCCCTTCTTTCTGGTTGGTGCTG

>25381_25381_7_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000427683_C20orf96_chr20_264722_ENST00000360321_length(amino acids)=457AA_BP=157
MRLLPLLRTVLWAAFLGSPLRGGSSLRHVVYWNSSNPRLLRGDAVVELGLNDYLDIVCPHYEGPGPPEGPETFALYMVDWPGYESCQAEG
PRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYISVPTPESSGQCLRLQVSVCCKERMFHFKPTTVVTSCQPKNPRELHRR
RKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSEL
QEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKK
KKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREIIDQFEENMPVLRAEVEELQAQTREPREVIFEDVLLRRPKCTPDMDVILNIP

--------------------------------------------------------------
>25381_25381_8_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000427683_C20orf96_chr20_264722_ENST00000382369_length(transcript)=1781nt_BP=532nt
CTCTCCTCGACTGTGAAGCGGGCCGGGACCTGCCAGGCCAGACCAAACCGGACCTCGGGGGCGATGCGGCTGCTGCCCCTGCTGCGGACT
GTCCTCTGGGCCGCGTTCCTCGGCTCCCCTCTGCGCGGGGGCTCCAGCCTCCGCCACGTAGTCTACTGGAACTCCAGTAACCCCAGGTTG
CTTCGAGGAGACGCCGTGGTGGAGCTGGGCCTCAACGATTACCTAGACATTGTCTGCCCCCACTACGAAGGCCCAGGGCCCCCTGAGGGC
CCCGAGACGTTTGCTTTGTACATGGTGGACTGGCCAGGCTATGAGTCCTGCCAGGCAGAGGGCCCCCGGGCCTACAAGCGCTGGGTGTGC
TCCCTGCCCTTTGGCCATGTTCAATTCTCAGAGAAGATTCAGCGCTTCACACCCTTCTCCCTCGGCTTTGAGTTCTTACCTGGAGAGACT
TACTACTACATCTCGGTGCCCACTCCAGAGAGTTCTGGCCAGTGCTTGAGGCTCCAGGTGTCTGTCTGCTGCAAGGAGAGGATGTTTCAC
TTCAAGCCCACTACGGTGGTGACAAGCTGCCAGCCGAAGAATCCAAGAGAACTACATAGAAGGCGGAAGTTGGACCCTGGGAAGATGCAT
GCCAAAATCTGGTTAATGAAGACCTCGCTCAGGAGCGGGAGGGCCGCTCTGCGAGAGCTCCGAAGCCGTGAGAACTTCCTCAGCAAGCTC
AACCGGGAGCTGATCGAGACCATCCAGGAGATGGAGAACAGCACGACCCTGCACGTGCGGGCCCTGCTGCAGCAGCAGGACACCCTGGCG
ACCATCATCGACATCTTGGAGTACTCAAACAAGAAGAGGCTGCAGCAATTGAAATCTGAGCTTCAGGAGTGGGAAGAAAAGAAGAAATGC
AAGATGAGCTATCTTGAGCAGCAGGCAGAGCAGCTGAATGCCAAGATTGAGAAGACCCAGGAGGAAGTGAACTTCCTGAGCACTTACATG
GACCATGAGTATTCCATCAAGTCTGTCCAGATCTCCACTCTTATGCGCCAGCTGCAGCAGGTTAAGGACAGCCAGCAGGATGAGCTGGAT
GACCTCGGTGAGATGCGCAGAAAGGTCCTGGAATCCTTGTCTGACAAGATTCAGAAGAAGAAGAAAAAAATTCTGAGTTCTGTGGTGGCG
GAAACCCAGCGTCCCTATGAAGAGGCTCTCCTACAGAAGATGTGGGAAAGCCAGGACTTCCTGAAATGCATGCAAAGGTTCAGAGAAATT
ATTGACCAGTTTGAGGAGAACATGCCTGTATTAAGGGCCGAGGTGGAAGAGCTCCAAGCCCAGACCCGGGAACCCCGAGAGGTCATATTT
GAGGATGTTCTGCTTCGGAGACCCAAGTGCACCCCAGACATGGATGTCATCCTCAACATTCCTGTGGAAGAGCCACTACCCTTCTAGATG
GCAGTGCCATGGGCCGCCCTCCCCTCCTGCTCTCTTCCCAGCACCTGGAGCCTTGGATCATTTACTTCCAGGACCGGATCTCCATTCAGA
CCCTGATCTACAGTCTCCCTGCTCCCTCTGCCCTTCCTCCCTCTTTCTTTCCCTCCCTCCCTCCCTCCCTTCTTCCCCCCTTCCCTTCCC
TCCTCCTTCCTTCCTCCTCTCCCTCCCTCCCTCCTTTCTTTCTTCCTGTGGTTTTTTCCTCTCTTCTTCCCTTCTTTCTGGTTGGTGCTG

>25381_25381_8_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000427683_C20orf96_chr20_264722_ENST00000382369_length(amino acids)=457AA_BP=157
MRLLPLLRTVLWAAFLGSPLRGGSSLRHVVYWNSSNPRLLRGDAVVELGLNDYLDIVCPHYEGPGPPEGPETFALYMVDWPGYESCQAEG
PRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYISVPTPESSGQCLRLQVSVCCKERMFHFKPTTVVTSCQPKNPRELHRR
RKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSEL
QEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKK
KKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREIIDQFEENMPVLRAEVEELQAQTREPREVIFEDVLLRRPKCTPDMDVILNIP

--------------------------------------------------------------
>25381_25381_9_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000427683_C20orf96_chr20_264722_ENST00000400269_length(transcript)=1481nt_BP=532nt
CTCTCCTCGACTGTGAAGCGGGCCGGGACCTGCCAGGCCAGACCAAACCGGACCTCGGGGGCGATGCGGCTGCTGCCCCTGCTGCGGACT
GTCCTCTGGGCCGCGTTCCTCGGCTCCCCTCTGCGCGGGGGCTCCAGCCTCCGCCACGTAGTCTACTGGAACTCCAGTAACCCCAGGTTG
CTTCGAGGAGACGCCGTGGTGGAGCTGGGCCTCAACGATTACCTAGACATTGTCTGCCCCCACTACGAAGGCCCAGGGCCCCCTGAGGGC
CCCGAGACGTTTGCTTTGTACATGGTGGACTGGCCAGGCTATGAGTCCTGCCAGGCAGAGGGCCCCCGGGCCTACAAGCGCTGGGTGTGC
TCCCTGCCCTTTGGCCATGTTCAATTCTCAGAGAAGATTCAGCGCTTCACACCCTTCTCCCTCGGCTTTGAGTTCTTACCTGGAGAGACT
TACTACTACATCTCGGTGCCCACTCCAGAGAGTTCTGGCCAGTGCTTGAGGCTCCAGGTGTCTGTCTGCTGCAAGGAGAGGATGTTTCAC
TTCAAGCCCACTACGGTGGTGACAAGCTGCCAGCCGAAGAATCCAAGAGAACTACATAGAAGGCGGAAGTTGGACCCTGGGAAGATGCAT
GCCAAAATCTGGTTAATGAAGACCTCGCTCAGGAGCGGGAGGGCCGCTCTGCGAGAGCTCCGAAGCCGTGAGAACTTCCTCAGCAAGCTC
AACCGGGAGCTGATCGAGACCATCCAGGAGATGGAGAACAGCACGACCCTGCACGTGCGGGCCCTGCTGCAGCAGCAGGACACCCTGGCG
ACCATCATCGACATCTTGGAGTACTCAAACAAGAAGAGGCTGCAGCAATTGAAATCTGAGCTTCAGGAGTGGGAAGAAAAGAAGAAATGC
AAGATGAGCTATCTTGAGCAGCAGGCAGAGCAGCTGAATGCCAAGATTGAGAAGACCCAGGAGGAAGTGAACTTCCTGAGCACTTACATG
GACCATGAGTATTCCATCAAGTCTGTCCAGATCTCCACTCTTATGCGCCAGCTGCAGCAGGTTAAGGACAGCCAGCAGGATGAGCTGGAT
GACCTCGGTGAGATGCGCAGAAAGGTCCTGGAATCCTTGTCTGACAAGATTCAGAAGAAGAAGAAAAAAATTCTGAGTTCTGTGGTGGCG
GAAACCCAGCGTCCCTATGAAGAGGCTCTCCTACAGAAGATGTGGGAAAGCCAGGACTTCCTGAAATGCATGCAAAGGTTCAGAGAAGTG
CGTGGGCAAGGAAGGTGGTGGTCCCTGTAGGGAAGCAGTGGATGGGCAGTCCCCACGGCCTGTGGGAATGAGTCAGGCTTCTCCTGATCT
GGCGCTCAGGAGGTCTCTGACTCTGGTGTTGGCCTCCCTCCTTGCCGGTGCCATTACTGTCACTTGTCTTTCATCTGGGAAGGCGATTGG

>25381_25381_9_EFNA4-C20orf96_EFNA4_chr1_155039916_ENST00000427683_C20orf96_chr20_264722_ENST00000400269_length(amino acids)=408AA_BP=157
MRLLPLLRTVLWAAFLGSPLRGGSSLRHVVYWNSSNPRLLRGDAVVELGLNDYLDIVCPHYEGPGPPEGPETFALYMVDWPGYESCQAEG
PRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYISVPTPESSGQCLRLQVSVCCKERMFHFKPTTVVTSCQPKNPRELHRR
RKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSEL
QEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for EFNA4-C20orf96


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EFNA4-C20orf96


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for EFNA4-C20orf96


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource