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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ELK1-FLI1 (FusionGDB2 ID:HG2002TG2313)

Fusion Gene Summary for ELK1-FLI1

check button Fusion gene summary
Fusion gene informationFusion gene name: ELK1-FLI1
Fusion gene ID: hg2002tg2313
HgeneTgene
Gene symbol

ELK1

FLI1

Gene ID

2002

2313

Gene nameETS transcription factor ELK1Fli-1 proto-oncogene, ETS transcription factor
Synonyms-BDPLT21|EWSR2|SIC-1
Cytomap('ELK1')('FLI1')

Xp11.23

11q24.3

Type of geneprotein-codingprotein-coding
DescriptionETS domain-containing protein Elk-1ELK1, ETS transcription factorELK1, member of ETS oncogene familyETS-like gene 1tyrosine kinase (ELK1) oncogeneFriend leukemia integration 1 transcription factorEwing sarcoma breakpoint region 2Friend leukemia virus integration 1transcription factor ERGB
Modification date2020031320200313
UniProtAcc

P19419

Q01543

Ensembl transtripts involved in fusion geneENST00000247161, ENST00000343894, 
ENST00000376983, ENST00000592066, 
ENST00000468956, 
Fusion gene scores* DoF score6 X 6 X 4=1445 X 70 X 4=1400
# samples 668
** MAII scorelog2(6/144*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(68/1400*10)=-1.04182017569463
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ELK1 [Title/Abstract] AND FLI1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointELK1(47500631)-FLI1(128680500), # samples:1
Anticipated loss of major functional domain due to fusion event.ELK1-FLI1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ELK1-FLI1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ELK1-FLI1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ELK1-FLI1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ELK1-FLI1 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
ELK1-FLI1 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
ELK1-FLI1 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneELK1

GO:0045893

positive regulation of transcription, DNA-templated

15790681|17296730

HgeneELK1

GO:0045944

positive regulation of transcription by RNA polymerase II

12750007|14970218

TgeneFLI1

GO:0045893

positive regulation of transcription, DNA-templated

26316623


check buttonFusion gene breakpoints across ELK1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across FLI1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerERR188262ELK1chrX

47500631

-FLI1chr11

128680500

+


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Fusion Gene ORF analysis for ELK1-FLI1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000247161ENST00000525560ELK1chrX

47500631

-FLI1chr11

128680500

+
Frame-shiftENST00000247161ENST00000527786ELK1chrX

47500631

-FLI1chr11

128680500

+
Frame-shiftENST00000247161ENST00000534087ELK1chrX

47500631

-FLI1chr11

128680500

+
Frame-shiftENST00000343894ENST00000525560ELK1chrX

47500631

-FLI1chr11

128680500

+
Frame-shiftENST00000343894ENST00000527786ELK1chrX

47500631

-FLI1chr11

128680500

+
Frame-shiftENST00000343894ENST00000534087ELK1chrX

47500631

-FLI1chr11

128680500

+
Frame-shiftENST00000376983ENST00000281428ELK1chrX

47500631

-FLI1chr11

128680500

+
Frame-shiftENST00000376983ENST00000344954ELK1chrX

47500631

-FLI1chr11

128680500

+
Frame-shiftENST00000376983ENST00000527786ELK1chrX

47500631

-FLI1chr11

128680500

+
Frame-shiftENST00000376983ENST00000534087ELK1chrX

47500631

-FLI1chr11

128680500

+
Frame-shiftENST00000592066ENST00000525560ELK1chrX

47500631

-FLI1chr11

128680500

+
Frame-shiftENST00000592066ENST00000527786ELK1chrX

47500631

-FLI1chr11

128680500

+
Frame-shiftENST00000592066ENST00000534087ELK1chrX

47500631

-FLI1chr11

128680500

+
In-frameENST00000247161ENST00000281428ELK1chrX

47500631

-FLI1chr11

128680500

+
In-frameENST00000247161ENST00000344954ELK1chrX

47500631

-FLI1chr11

128680500

+
In-frameENST00000343894ENST00000281428ELK1chrX

47500631

-FLI1chr11

128680500

+
In-frameENST00000343894ENST00000344954ELK1chrX

47500631

-FLI1chr11

128680500

+
In-frameENST00000376983ENST00000525560ELK1chrX

47500631

-FLI1chr11

128680500

+
In-frameENST00000592066ENST00000281428ELK1chrX

47500631

-FLI1chr11

128680500

+
In-frameENST00000592066ENST00000344954ELK1chrX

47500631

-FLI1chr11

128680500

+
intron-3CDSENST00000468956ENST00000281428ELK1chrX

47500631

-FLI1chr11

128680500

+
intron-3CDSENST00000468956ENST00000344954ELK1chrX

47500631

-FLI1chr11

128680500

+
intron-3CDSENST00000468956ENST00000525560ELK1chrX

47500631

-FLI1chr11

128680500

+
intron-3CDSENST00000468956ENST00000527786ELK1chrX

47500631

-FLI1chr11

128680500

+
intron-3CDSENST00000468956ENST00000534087ELK1chrX

47500631

-FLI1chr11

128680500

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000247161ELK1chrX47500631-ENST00000344954FLI1chr11128680500+2971310321692123
ENST00000247161ELK1chrX47500631-ENST00000281428FLI1chr11128680500+2971310321692123
ENST00000592066ELK1chrX47500631-ENST00000344954FLI1chr11128680500+2971310321692123
ENST00000592066ELK1chrX47500631-ENST00000281428FLI1chr11128680500+2971310321692123
ENST00000376983ELK1chrX47500631-ENST00000525560FLI1chr11128680500+1310519530901123
ENST00000343894ELK1chrX47500631-ENST00000344954FLI1chr11128680500+308742648440130
ENST00000343894ELK1chrX47500631-ENST00000281428FLI1chr11128680500+308742648440130

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000247161ENST00000344954ELK1chrX47500631-FLI1chr11128680500+0.0153886970.98461133
ENST00000247161ENST00000281428ELK1chrX47500631-FLI1chr11128680500+0.0153886970.98461133
ENST00000592066ENST00000344954ELK1chrX47500631-FLI1chr11128680500+0.0153886970.98461133
ENST00000592066ENST00000281428ELK1chrX47500631-FLI1chr11128680500+0.0153886970.98461133
ENST00000376983ENST00000525560ELK1chrX47500631-FLI1chr11128680500+0.0068354630.9931645
ENST00000343894ENST00000344954ELK1chrX47500631-FLI1chr11128680500+0.0100460120.989954
ENST00000343894ENST00000281428ELK1chrX47500631-FLI1chr11128680500+0.0100460120.989954

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Fusion Genomic Features for ELK1-FLI1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ELK1-FLI1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrX:47500631/chr11:128680500)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ELK1

P19419

FLI1

Q01543

FUNCTION: Transcription factor that binds to purine-rich DNA sequences. Forms a ternary complex with SRF and the ETS and SRF motifs of the serum response element (SRE) on the promoter region of immediate early genes such as FOS and IER2. Induces target gene transcription upon JNK-signaling pathway stimulation (By similarity). {ECO:0000250|UniProtKB:A4GTP4, ECO:0000269|PubMed:1630903, ECO:0000269|PubMed:7889942}.FUNCTION: Sequence-specific transcriptional activator (PubMed:24100448, PubMed:26316623, PubMed:28255014). Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'. {ECO:0000269|PubMed:24100448, ECO:0000269|PubMed:26316623, ECO:0000269|PubMed:28255014}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneFLI1chrX:47500631chr11:128680500ENST0000028142808281_3610387.0DNA bindingETS
TgeneFLI1chrX:47500631chr11:128680500ENST0000034495409281_3610420.0DNA bindingETS
TgeneFLI1chrX:47500631chr11:128680500ENST0000052556007281_3610260.0DNA bindingETS
TgeneFLI1chrX:47500631chr11:128680500ENST00000534087010281_3610420.0DNA bindingETS
TgeneFLI1chrX:47500631chr11:128680500ENST0000028142808112_1980387.0DomainPNT
TgeneFLI1chrX:47500631chr11:128680500ENST0000034495409112_1980420.0DomainPNT
TgeneFLI1chrX:47500631chr11:128680500ENST0000052556007112_1980260.0DomainPNT
TgeneFLI1chrX:47500631chr11:128680500ENST00000534087010112_1980420.0DomainPNT

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneELK1chrX:47500631chr11:128680500ENST00000247161-265_8670429.0DNA bindingETS
HgeneELK1chrX:47500631chr11:128680500ENST00000343894-245_867096.0DNA bindingETS
HgeneELK1chrX:47500631chr11:128680500ENST00000376983-375_8670429.0DNA bindingETS


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Fusion Gene Sequence for ELK1-FLI1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>26186_26186_1_ELK1-FLI1_ELK1_chrX_47500631_ENST00000247161_FLI1_chr11_128680500_ENST00000281428_length(transcript)=2971nt_BP=310nt
CGCGTATGGAGCCCCCGCCCCCCGGAGCTGCCAACATTGCCAACGCCACCGCCACGCTACACACAGGTACCCCTGGGATGGCGTGAGCAC
TCCCCCAGCGATGGACCCATCTGTGACGCTGTGGCAGTTTCTGCTGCAGCTGCTGAGAGAGCAAGGCAATGGCCACATCATCTCCTGGAC
TTCACGGGATGGTGGTGAATTCAAGCTGGTGGATGCAGAGGAGGTGGCCCGGCTGTGGGGGCTACGCAAGAACAAGACCAACATGAATTA
CGACAAGCTCAGCCGGGCCTTGCGGTACTACTATGACAAGGCAAGCCCAACATGAATTACGACAAGCTGAGCCGGGCCCTCCGTTATTAC
TATGATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACAT
CCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCT
CCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCC
AACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTACTAGAAGCTTACTCATCAGTGGCCTTCTAGC
TGAAGCCCATCCTGCACACTTACTGGATGCTTTGGACTCAACAGGACATATGTGGCCTTGAAGGGAAGACAAAACTGGATGTTCTTTCTT
GTTGGATAGAACCTTTGTATTTGTTCTTTAAAAACATTTTTTTTAATGTTGGTAACTTTTGCTTCCTCTACCTGAACAAAGAGATGAATA
ATTCCATGGGCCAGTATGCCAGTTTGAATTCTCAGTCTCCTAGCATCTTGTGAGTTGCATATTAAGATTACTGGAATGGTTAAGTCATGG
TTCTGAGAAAGAAGCTGTACGTTTTCTTTATGTTTTTATGACCAAAGCAGTTTCTTGTCAATACACGGGGTTCAGTATGACACAGAATCA
TGGACTTAACCCGTCATGTTCTGGTTTGAGATTTAGTGACAAATAGAGGTGGGAAGCTTATAATCTAATTTTAGGAGGACCAAATTCAGT
GGATGGCAACTGGAACATTGATTGTAAGGCCAGTGAAGTTTTCACCCAACTGGAATTTGATGGAAAGAAGGTTTGTGTGTTTAAGACGCC
AAGGGCATTGCAGAATCCCTCTCAGTGGACAGTATGCACTCAGCTGACCACTCTCTCTAGAAATAGTCAAGATATGAACTAAGAAATTTT
AATGCAAATACATACATTCCTGAAAGACGGGGAATTAAATTACTAATTTTTTTTTTTTTTTAAATGATGACAGTGGTCCCAGAACTTGGA
AAAGTTGTAGGGATTTCTAAACTCAAGCAGATTCGCAAGTGCTGTGCGCTTGTCAGACCATCAGACCAGGGCCAACCAATCAGAAGGCAA
CTTACTGTATAAATTATGCAGAGTTATTTTCCTATATCTCACAGTATTAAAAATAAATAATTAAAAATTAAGAATAAATAAACGAGTTGA
CCTCGGTCACAAAAGCAGTTTTACTATCGAATCAATCGCTGTTATTTTTTTTAATGTAATTTGTACATCTTTTTTCAATCTGTACATTTG
GGCTGTCTGTATGTTTTTATAGCTGGTTTTTAAAAAGCATAATATGCCTATAGCTGAAAAGGAAACAGGGCTGTTTAAGTCACTGACTTA
TGAGAAAGCAAAGCACTGGTACAGTTATTTAACAGGCATACACAAGCAGGGAAAAGATAATCCATTTAGATCTTTAATGCTTTGGAAATG
CGTGTAACAGTACTGCAATAATCACAGCTCTGGGAAAAACAACGAAACTTTCCCTTGTGGAGAGGAGGGATTTTCCTGCTCTATATAAGC
AACATATTTTTAGACATTAAAATATATATAATTTTGCAGGTAATTGTTGACTTTTTTAACTATATTAAGTGTTAAGCTGACAACTGTCAA
AGAAGACCATGTTGTAAAATAATTTGACTAAATAAATGGTTCCTTCTCTCAGTGCTGAGGACAGTTTTCTTATTTACCGCCCCCGTTAGG
TCAAAGGGTTTTCCCTGGGGAACTTTCCTATTTACTTCTTGCACTATCAAGAATTTTTCGAATGTACCTACTGCAGTACAGCAGAAGGTA
AAAAATCAGTGTGGTTTTTCATTGTTGTTGATGATGTTTGTAGTGTTTTTGTGTGTGTTATTTAAATCTTCCTCCAGCCTAAAAGGGTTT
TATAAAACAGCAGCTAAGGCCATGGATAAACCTGTATGTAAGGACTGGAGCAAAGCGAGCTGGTCTATCCAGACTGGTCTGTGAGATTTA
ACTCTGCAGCCTCCCCTGGGCACTTCAGACCCAGACGGCCACCTTCTGCCACTCCAGCAAAGAATAAGCGCCCTGCTTCCTTCAGGTCTC
AGACCAGGACTTTATGGCTCATGCAGATTTTTAAGGTCATTTTTCTTCCCAAGGAAGAAACTTGCCTCCAGTTCCTTCACTGTTAGGTAG
CTTATTTTCATTTTCTCTATTTTACAATGAAAAGAGTGAGACCTGGGAAGTCCTTGATTTGCAAGGAATTAGACTCACAGCATTGGTAAC
CCTAGAACCTTCTTAGGGTAACACTAAGTACCTTCTAGACAACATGTCTACCTAAATGAAATGGGATGTGTTTCGGAACATTTGTCTCCA
GTTTTTTTTTAATCTTGCACCCTGCCATTTAAAAAGATGTGTAAAGCACATATTCTCAACATATGCACATTGATTTATAAATCATATATA
CAAACTGTTACATTATTCTTCATATTAGAAAACAAATACAAAATAGAACATTTTAAATGGTGATATAAAAATAAATTGAAACTGAAATTC
T

>26186_26186_1_ELK1-FLI1_ELK1_chrX_47500631_ENST00000247161_FLI1_chr11_128680500_ENST00000281428_length(amino acids)=123AA_BP=
MNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAA
SQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY

--------------------------------------------------------------
>26186_26186_2_ELK1-FLI1_ELK1_chrX_47500631_ENST00000247161_FLI1_chr11_128680500_ENST00000344954_length(transcript)=2971nt_BP=310nt
CGCGTATGGAGCCCCCGCCCCCCGGAGCTGCCAACATTGCCAACGCCACCGCCACGCTACACACAGGTACCCCTGGGATGGCGTGAGCAC
TCCCCCAGCGATGGACCCATCTGTGACGCTGTGGCAGTTTCTGCTGCAGCTGCTGAGAGAGCAAGGCAATGGCCACATCATCTCCTGGAC
TTCACGGGATGGTGGTGAATTCAAGCTGGTGGATGCAGAGGAGGTGGCCCGGCTGTGGGGGCTACGCAAGAACAAGACCAACATGAATTA
CGACAAGCTCAGCCGGGCCTTGCGGTACTACTATGACAAGGCAAGCCCAACATGAATTACGACAAGCTGAGCCGGGCCCTCCGTTATTAC
TATGATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACAT
CCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCT
CCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCC
AACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTACTAGAAGCTTACTCATCAGTGGCCTTCTAGC
TGAAGCCCATCCTGCACACTTACTGGATGCTTTGGACTCAACAGGACATATGTGGCCTTGAAGGGAAGACAAAACTGGATGTTCTTTCTT
GTTGGATAGAACCTTTGTATTTGTTCTTTAAAAACATTTTTTTTAATGTTGGTAACTTTTGCTTCCTCTACCTGAACAAAGAGATGAATA
ATTCCATGGGCCAGTATGCCAGTTTGAATTCTCAGTCTCCTAGCATCTTGTGAGTTGCATATTAAGATTACTGGAATGGTTAAGTCATGG
TTCTGAGAAAGAAGCTGTACGTTTTCTTTATGTTTTTATGACCAAAGCAGTTTCTTGTCAATACACGGGGTTCAGTATGACACAGAATCA
TGGACTTAACCCGTCATGTTCTGGTTTGAGATTTAGTGACAAATAGAGGTGGGAAGCTTATAATCTAATTTTAGGAGGACCAAATTCAGT
GGATGGCAACTGGAACATTGATTGTAAGGCCAGTGAAGTTTTCACCCAACTGGAATTTGATGGAAAGAAGGTTTGTGTGTTTAAGACGCC
AAGGGCATTGCAGAATCCCTCTCAGTGGACAGTATGCACTCAGCTGACCACTCTCTCTAGAAATAGTCAAGATATGAACTAAGAAATTTT
AATGCAAATACATACATTCCTGAAAGACGGGGAATTAAATTACTAATTTTTTTTTTTTTTTAAATGATGACAGTGGTCCCAGAACTTGGA
AAAGTTGTAGGGATTTCTAAACTCAAGCAGATTCGCAAGTGCTGTGCGCTTGTCAGACCATCAGACCAGGGCCAACCAATCAGAAGGCAA
CTTACTGTATAAATTATGCAGAGTTATTTTCCTATATCTCACAGTATTAAAAATAAATAATTAAAAATTAAGAATAAATAAACGAGTTGA
CCTCGGTCACAAAAGCAGTTTTACTATCGAATCAATCGCTGTTATTTTTTTTAATGTAATTTGTACATCTTTTTTCAATCTGTACATTTG
GGCTGTCTGTATGTTTTTATAGCTGGTTTTTAAAAAGCATAATATGCCTATAGCTGAAAAGGAAACAGGGCTGTTTAAGTCACTGACTTA
TGAGAAAGCAAAGCACTGGTACAGTTATTTAACAGGCATACACAAGCAGGGAAAAGATAATCCATTTAGATCTTTAATGCTTTGGAAATG
CGTGTAACAGTACTGCAATAATCACAGCTCTGGGAAAAACAACGAAACTTTCCCTTGTGGAGAGGAGGGATTTTCCTGCTCTATATAAGC
AACATATTTTTAGACATTAAAATATATATAATTTTGCAGGTAATTGTTGACTTTTTTAACTATATTAAGTGTTAAGCTGACAACTGTCAA
AGAAGACCATGTTGTAAAATAATTTGACTAAATAAATGGTTCCTTCTCTCAGTGCTGAGGACAGTTTTCTTATTTACCGCCCCCGTTAGG
TCAAAGGGTTTTCCCTGGGGAACTTTCCTATTTACTTCTTGCACTATCAAGAATTTTTCGAATGTACCTACTGCAGTACAGCAGAAGGTA
AAAAATCAGTGTGGTTTTTCATTGTTGTTGATGATGTTTGTAGTGTTTTTGTGTGTGTTATTTAAATCTTCCTCCAGCCTAAAAGGGTTT
TATAAAACAGCAGCTAAGGCCATGGATAAACCTGTATGTAAGGACTGGAGCAAAGCGAGCTGGTCTATCCAGACTGGTCTGTGAGATTTA
ACTCTGCAGCCTCCCCTGGGCACTTCAGACCCAGACGGCCACCTTCTGCCACTCCAGCAAAGAATAAGCGCCCTGCTTCCTTCAGGTCTC
AGACCAGGACTTTATGGCTCATGCAGATTTTTAAGGTCATTTTTCTTCCCAAGGAAGAAACTTGCCTCCAGTTCCTTCACTGTTAGGTAG
CTTATTTTCATTTTCTCTATTTTACAATGAAAAGAGTGAGACCTGGGAAGTCCTTGATTTGCAAGGAATTAGACTCACAGCATTGGTAAC
CCTAGAACCTTCTTAGGGTAACACTAAGTACCTTCTAGACAACATGTCTACCTAAATGAAATGGGATGTGTTTCGGAACATTTGTCTCCA
GTTTTTTTTTAATCTTGCACCCTGCCATTTAAAAAGATGTGTAAAGCACATATTCTCAACATATGCACATTGATTTATAAATCATATATA
CAAACTGTTACATTATTCTTCATATTAGAAAACAAATACAAAATAGAACATTTTAAATGGTGATATAAAAATAAATTGAAACTGAAATTC
T

>26186_26186_2_ELK1-FLI1_ELK1_chrX_47500631_ENST00000247161_FLI1_chr11_128680500_ENST00000344954_length(amino acids)=123AA_BP=
MNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAA
SQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY

--------------------------------------------------------------
>26186_26186_3_ELK1-FLI1_ELK1_chrX_47500631_ENST00000343894_FLI1_chr11_128680500_ENST00000281428_length(transcript)=3087nt_BP=426nt
CTCGGGCCCACGTGAGCTGTAGGGAAACGCAGGGGCGGCTTCTAGGTGCTGCCGCCGCCACCGCCACCACCACCTCCACCGCCGCCTCGG
AACCCAGGCCTGGGGGGCGGTGGGGCCGCGTATGGAGCCCCCGCCCCCCGGAGCTGCCAACATTGCCAACGCCACCGCCACGCTACACAC
AGGTACCCCTGGGATGGCGTGAGCACTCCCCCAGCGATGGACCCATCTGTGACGCTGTGGCAGTTTCTGCTGCAGCTGCTGAGAGAGCAA
GGCAATGGCCACATCATCTCCTGGACTTCACGGGATGGTGGTGAATTCAAGCTGGTGGATGCAGAGGAGGTGGCCCGGCTGTGGGGGCTA
CGCAAGAACAAGACCAACATGAATTACGACAAGCTCAGCCGGGCCTTGCGGTACTACTATGACAAGGCAAGCCCAACATGAATTACGACA
AGCTGAGCCGGGCCCTCCGTTATTACTATGATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACG
GCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCC
ACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGA
CCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTACTAGA
AGCTTACTCATCAGTGGCCTTCTAGCTGAAGCCCATCCTGCACACTTACTGGATGCTTTGGACTCAACAGGACATATGTGGCCTTGAAGG
GAAGACAAAACTGGATGTTCTTTCTTGTTGGATAGAACCTTTGTATTTGTTCTTTAAAAACATTTTTTTTAATGTTGGTAACTTTTGCTT
CCTCTACCTGAACAAAGAGATGAATAATTCCATGGGCCAGTATGCCAGTTTGAATTCTCAGTCTCCTAGCATCTTGTGAGTTGCATATTA
AGATTACTGGAATGGTTAAGTCATGGTTCTGAGAAAGAAGCTGTACGTTTTCTTTATGTTTTTATGACCAAAGCAGTTTCTTGTCAATAC
ACGGGGTTCAGTATGACACAGAATCATGGACTTAACCCGTCATGTTCTGGTTTGAGATTTAGTGACAAATAGAGGTGGGAAGCTTATAAT
CTAATTTTAGGAGGACCAAATTCAGTGGATGGCAACTGGAACATTGATTGTAAGGCCAGTGAAGTTTTCACCCAACTGGAATTTGATGGA
AAGAAGGTTTGTGTGTTTAAGACGCCAAGGGCATTGCAGAATCCCTCTCAGTGGACAGTATGCACTCAGCTGACCACTCTCTCTAGAAAT
AGTCAAGATATGAACTAAGAAATTTTAATGCAAATACATACATTCCTGAAAGACGGGGAATTAAATTACTAATTTTTTTTTTTTTTTAAA
TGATGACAGTGGTCCCAGAACTTGGAAAAGTTGTAGGGATTTCTAAACTCAAGCAGATTCGCAAGTGCTGTGCGCTTGTCAGACCATCAG
ACCAGGGCCAACCAATCAGAAGGCAACTTACTGTATAAATTATGCAGAGTTATTTTCCTATATCTCACAGTATTAAAAATAAATAATTAA
AAATTAAGAATAAATAAACGAGTTGACCTCGGTCACAAAAGCAGTTTTACTATCGAATCAATCGCTGTTATTTTTTTTAATGTAATTTGT
ACATCTTTTTTCAATCTGTACATTTGGGCTGTCTGTATGTTTTTATAGCTGGTTTTTAAAAAGCATAATATGCCTATAGCTGAAAAGGAA
ACAGGGCTGTTTAAGTCACTGACTTATGAGAAAGCAAAGCACTGGTACAGTTATTTAACAGGCATACACAAGCAGGGAAAAGATAATCCA
TTTAGATCTTTAATGCTTTGGAAATGCGTGTAACAGTACTGCAATAATCACAGCTCTGGGAAAAACAACGAAACTTTCCCTTGTGGAGAG
GAGGGATTTTCCTGCTCTATATAAGCAACATATTTTTAGACATTAAAATATATATAATTTTGCAGGTAATTGTTGACTTTTTTAACTATA
TTAAGTGTTAAGCTGACAACTGTCAAAGAAGACCATGTTGTAAAATAATTTGACTAAATAAATGGTTCCTTCTCTCAGTGCTGAGGACAG
TTTTCTTATTTACCGCCCCCGTTAGGTCAAAGGGTTTTCCCTGGGGAACTTTCCTATTTACTTCTTGCACTATCAAGAATTTTTCGAATG
TACCTACTGCAGTACAGCAGAAGGTAAAAAATCAGTGTGGTTTTTCATTGTTGTTGATGATGTTTGTAGTGTTTTTGTGTGTGTTATTTA
AATCTTCCTCCAGCCTAAAAGGGTTTTATAAAACAGCAGCTAAGGCCATGGATAAACCTGTATGTAAGGACTGGAGCAAAGCGAGCTGGT
CTATCCAGACTGGTCTGTGAGATTTAACTCTGCAGCCTCCCCTGGGCACTTCAGACCCAGACGGCCACCTTCTGCCACTCCAGCAAAGAA
TAAGCGCCCTGCTTCCTTCAGGTCTCAGACCAGGACTTTATGGCTCATGCAGATTTTTAAGGTCATTTTTCTTCCCAAGGAAGAAACTTG
CCTCCAGTTCCTTCACTGTTAGGTAGCTTATTTTCATTTTCTCTATTTTACAATGAAAAGAGTGAGACCTGGGAAGTCCTTGATTTGCAA
GGAATTAGACTCACAGCATTGGTAACCCTAGAACCTTCTTAGGGTAACACTAAGTACCTTCTAGACAACATGTCTACCTAAATGAAATGG
GATGTGTTTCGGAACATTTGTCTCCAGTTTTTTTTTAATCTTGCACCCTGCCATTTAAAAAGATGTGTAAAGCACATATTCTCAACATAT
GCACATTGATTTATAAATCATATATACAAACTGTTACATTATTCTTCATATTAGAAAACAAATACAAAATAGAACATTTTAAATGGTGAT
ATAAAAATAAATTGAAACTGAAATTCT

>26186_26186_3_ELK1-FLI1_ELK1_chrX_47500631_ENST00000343894_FLI1_chr11_128680500_ENST00000281428_length(amino acids)=130AA_BP=87
MPPPPPPPPPPPPRNPGLGGGGAAYGAPAPRSCQHCQRHRHATHRYPWDGVSTPPAMDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEF
KLVDAEEVARLWGLRKNKTNMNYDKLSRALRYYYDKASPT

--------------------------------------------------------------
>26186_26186_4_ELK1-FLI1_ELK1_chrX_47500631_ENST00000343894_FLI1_chr11_128680500_ENST00000344954_length(transcript)=3087nt_BP=426nt
CTCGGGCCCACGTGAGCTGTAGGGAAACGCAGGGGCGGCTTCTAGGTGCTGCCGCCGCCACCGCCACCACCACCTCCACCGCCGCCTCGG
AACCCAGGCCTGGGGGGCGGTGGGGCCGCGTATGGAGCCCCCGCCCCCCGGAGCTGCCAACATTGCCAACGCCACCGCCACGCTACACAC
AGGTACCCCTGGGATGGCGTGAGCACTCCCCCAGCGATGGACCCATCTGTGACGCTGTGGCAGTTTCTGCTGCAGCTGCTGAGAGAGCAA
GGCAATGGCCACATCATCTCCTGGACTTCACGGGATGGTGGTGAATTCAAGCTGGTGGATGCAGAGGAGGTGGCCCGGCTGTGGGGGCTA
CGCAAGAACAAGACCAACATGAATTACGACAAGCTCAGCCGGGCCTTGCGGTACTACTATGACAAGGCAAGCCCAACATGAATTACGACA
AGCTGAGCCGGGCCCTCCGTTATTACTATGATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACG
GCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCC
ACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGA
CCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTACTAGA
AGCTTACTCATCAGTGGCCTTCTAGCTGAAGCCCATCCTGCACACTTACTGGATGCTTTGGACTCAACAGGACATATGTGGCCTTGAAGG
GAAGACAAAACTGGATGTTCTTTCTTGTTGGATAGAACCTTTGTATTTGTTCTTTAAAAACATTTTTTTTAATGTTGGTAACTTTTGCTT
CCTCTACCTGAACAAAGAGATGAATAATTCCATGGGCCAGTATGCCAGTTTGAATTCTCAGTCTCCTAGCATCTTGTGAGTTGCATATTA
AGATTACTGGAATGGTTAAGTCATGGTTCTGAGAAAGAAGCTGTACGTTTTCTTTATGTTTTTATGACCAAAGCAGTTTCTTGTCAATAC
ACGGGGTTCAGTATGACACAGAATCATGGACTTAACCCGTCATGTTCTGGTTTGAGATTTAGTGACAAATAGAGGTGGGAAGCTTATAAT
CTAATTTTAGGAGGACCAAATTCAGTGGATGGCAACTGGAACATTGATTGTAAGGCCAGTGAAGTTTTCACCCAACTGGAATTTGATGGA
AAGAAGGTTTGTGTGTTTAAGACGCCAAGGGCATTGCAGAATCCCTCTCAGTGGACAGTATGCACTCAGCTGACCACTCTCTCTAGAAAT
AGTCAAGATATGAACTAAGAAATTTTAATGCAAATACATACATTCCTGAAAGACGGGGAATTAAATTACTAATTTTTTTTTTTTTTTAAA
TGATGACAGTGGTCCCAGAACTTGGAAAAGTTGTAGGGATTTCTAAACTCAAGCAGATTCGCAAGTGCTGTGCGCTTGTCAGACCATCAG
ACCAGGGCCAACCAATCAGAAGGCAACTTACTGTATAAATTATGCAGAGTTATTTTCCTATATCTCACAGTATTAAAAATAAATAATTAA
AAATTAAGAATAAATAAACGAGTTGACCTCGGTCACAAAAGCAGTTTTACTATCGAATCAATCGCTGTTATTTTTTTTAATGTAATTTGT
ACATCTTTTTTCAATCTGTACATTTGGGCTGTCTGTATGTTTTTATAGCTGGTTTTTAAAAAGCATAATATGCCTATAGCTGAAAAGGAA
ACAGGGCTGTTTAAGTCACTGACTTATGAGAAAGCAAAGCACTGGTACAGTTATTTAACAGGCATACACAAGCAGGGAAAAGATAATCCA
TTTAGATCTTTAATGCTTTGGAAATGCGTGTAACAGTACTGCAATAATCACAGCTCTGGGAAAAACAACGAAACTTTCCCTTGTGGAGAG
GAGGGATTTTCCTGCTCTATATAAGCAACATATTTTTAGACATTAAAATATATATAATTTTGCAGGTAATTGTTGACTTTTTTAACTATA
TTAAGTGTTAAGCTGACAACTGTCAAAGAAGACCATGTTGTAAAATAATTTGACTAAATAAATGGTTCCTTCTCTCAGTGCTGAGGACAG
TTTTCTTATTTACCGCCCCCGTTAGGTCAAAGGGTTTTCCCTGGGGAACTTTCCTATTTACTTCTTGCACTATCAAGAATTTTTCGAATG
TACCTACTGCAGTACAGCAGAAGGTAAAAAATCAGTGTGGTTTTTCATTGTTGTTGATGATGTTTGTAGTGTTTTTGTGTGTGTTATTTA
AATCTTCCTCCAGCCTAAAAGGGTTTTATAAAACAGCAGCTAAGGCCATGGATAAACCTGTATGTAAGGACTGGAGCAAAGCGAGCTGGT
CTATCCAGACTGGTCTGTGAGATTTAACTCTGCAGCCTCCCCTGGGCACTTCAGACCCAGACGGCCACCTTCTGCCACTCCAGCAAAGAA
TAAGCGCCCTGCTTCCTTCAGGTCTCAGACCAGGACTTTATGGCTCATGCAGATTTTTAAGGTCATTTTTCTTCCCAAGGAAGAAACTTG
CCTCCAGTTCCTTCACTGTTAGGTAGCTTATTTTCATTTTCTCTATTTTACAATGAAAAGAGTGAGACCTGGGAAGTCCTTGATTTGCAA
GGAATTAGACTCACAGCATTGGTAACCCTAGAACCTTCTTAGGGTAACACTAAGTACCTTCTAGACAACATGTCTACCTAAATGAAATGG
GATGTGTTTCGGAACATTTGTCTCCAGTTTTTTTTTAATCTTGCACCCTGCCATTTAAAAAGATGTGTAAAGCACATATTCTCAACATAT
GCACATTGATTTATAAATCATATATACAAACTGTTACATTATTCTTCATATTAGAAAACAAATACAAAATAGAACATTTTAAATGGTGAT
ATAAAAATAAATTGAAACTGAAATTCT

>26186_26186_4_ELK1-FLI1_ELK1_chrX_47500631_ENST00000343894_FLI1_chr11_128680500_ENST00000344954_length(amino acids)=130AA_BP=87
MPPPPPPPPPPPPRNPGLGGGGAAYGAPAPRSCQHCQRHRHATHRYPWDGVSTPPAMDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEF
KLVDAEEVARLWGLRKNKTNMNYDKLSRALRYYYDKASPT

--------------------------------------------------------------
>26186_26186_5_ELK1-FLI1_ELK1_chrX_47500631_ENST00000376983_FLI1_chr11_128680500_ENST00000525560_length(transcript)=1310nt_BP=519nt
GAGCTGTAGGGAAACGCAGGGGCGGCTTCTAGGTGCTGCCGCCGCCACCGCCACCACCACCTCCACCGCCGCCTCGGAACCCAGGCCTGG
GGGGCGGTGGGGCCGCGTATGGAGCCCCCGCCCCCCGGAGCTGCCAACATTGCCAACGCCACCGCCACGCTACACACAGCCTCAACTTTC
AGGAGACCCGTCCGTGGCCTTATTTATTCCACCCTTCCTGTACATCGTAGCGAATCAATCCGTGGCGCCGCACTCCTCCGCATCCCTCTT
TAACAGTACCCCTGGGATGGCGTGAGCACTCCCCCAGCGATGGACCCATCTGTGACGCTGTGGCAGTTTCTGCTGCAGCTGCTGAGAGAG
CAAGGCAATGGCCACATCATCTCCTGGACTTCACGGGATGGTGGTGAATTCAAGCTGGTGGATGCAGAGGAGGTGGCCCGGCTGTGGGGG
CTACGCAAGAACAAGACCAACATGAATTACGACAAGCTCAGCCGGGCCTTGCGGTACTACTATGACAAGGCAAGCCCAACATGAATTACG
ACAAGCTGAGCCGGGCCCTCCGTTATTACTATGATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCC
ACGGCATTGCCCAGGCTCTGCAGCCACATCCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATG
CCCACCAGCAGAAGGTGAACTTTGTCCCTCCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACT
GGACCTCCCCCACGGGGGGAATCTACCCCAACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTACT
AGAAGCTTACTCATCAGTGGCCTTCTAGCTGAAGCCCATCCTGCACACTTACTGGATGCTTTGGACTCAACAGGACATATGTGGCCTTGA
AGGGAAGACAAAACTGGATGTTCTTTCTTGTTGGATAGAACCTTTGTATTTGTTCTTTAAAAACATTTTTTTTAATGTTGGTAACTTTTG
CTTCCTCTACCTGAACAAAGAGATGAATAATTCCATGGGCCAGTATGCCAGTTTGAATTCTCAGTCTCCTAGCATCTTGTGAGTTGCATA
TTAAGATTACTGGAATGGTTAAGTCATGGTTCTGAGAAAGAAGCTGTACGTTTTCTTTATGTTTTTATGACCAAAGCAGTTTCTTGTCAA
TACACGGGGTTCAGTATGACACAGAATCATGGACTTAACCCGTCATGTTC

>26186_26186_5_ELK1-FLI1_ELK1_chrX_47500631_ENST00000376983_FLI1_chr11_128680500_ENST00000525560_length(amino acids)=123AA_BP=
MNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAA
SQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY

--------------------------------------------------------------
>26186_26186_6_ELK1-FLI1_ELK1_chrX_47500631_ENST00000592066_FLI1_chr11_128680500_ENST00000281428_length(transcript)=2971nt_BP=310nt
CGCGTATGGAGCCCCCGCCCCCCGGAGCTGCCAACATTGCCAACGCCACCGCCACGCTACACACAGGTACCCCTGGGATGGCGTGAGCAC
TCCCCCAGCGATGGACCCATCTGTGACGCTGTGGCAGTTTCTGCTGCAGCTGCTGAGAGAGCAAGGCAATGGCCACATCATCTCCTGGAC
TTCACGGGATGGTGGTGAATTCAAGCTGGTGGATGCAGAGGAGGTGGCCCGGCTGTGGGGGCTACGCAAGAACAAGACCAACATGAATTA
CGACAAGCTCAGCCGGGCCTTGCGGTACTACTATGACAAGGCAAGCCCAACATGAATTACGACAAGCTGAGCCGGGCCCTCCGTTATTAC
TATGATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACAT
CCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCT
CCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCC
AACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTACTAGAAGCTTACTCATCAGTGGCCTTCTAGC
TGAAGCCCATCCTGCACACTTACTGGATGCTTTGGACTCAACAGGACATATGTGGCCTTGAAGGGAAGACAAAACTGGATGTTCTTTCTT
GTTGGATAGAACCTTTGTATTTGTTCTTTAAAAACATTTTTTTTAATGTTGGTAACTTTTGCTTCCTCTACCTGAACAAAGAGATGAATA
ATTCCATGGGCCAGTATGCCAGTTTGAATTCTCAGTCTCCTAGCATCTTGTGAGTTGCATATTAAGATTACTGGAATGGTTAAGTCATGG
TTCTGAGAAAGAAGCTGTACGTTTTCTTTATGTTTTTATGACCAAAGCAGTTTCTTGTCAATACACGGGGTTCAGTATGACACAGAATCA
TGGACTTAACCCGTCATGTTCTGGTTTGAGATTTAGTGACAAATAGAGGTGGGAAGCTTATAATCTAATTTTAGGAGGACCAAATTCAGT
GGATGGCAACTGGAACATTGATTGTAAGGCCAGTGAAGTTTTCACCCAACTGGAATTTGATGGAAAGAAGGTTTGTGTGTTTAAGACGCC
AAGGGCATTGCAGAATCCCTCTCAGTGGACAGTATGCACTCAGCTGACCACTCTCTCTAGAAATAGTCAAGATATGAACTAAGAAATTTT
AATGCAAATACATACATTCCTGAAAGACGGGGAATTAAATTACTAATTTTTTTTTTTTTTTAAATGATGACAGTGGTCCCAGAACTTGGA
AAAGTTGTAGGGATTTCTAAACTCAAGCAGATTCGCAAGTGCTGTGCGCTTGTCAGACCATCAGACCAGGGCCAACCAATCAGAAGGCAA
CTTACTGTATAAATTATGCAGAGTTATTTTCCTATATCTCACAGTATTAAAAATAAATAATTAAAAATTAAGAATAAATAAACGAGTTGA
CCTCGGTCACAAAAGCAGTTTTACTATCGAATCAATCGCTGTTATTTTTTTTAATGTAATTTGTACATCTTTTTTCAATCTGTACATTTG
GGCTGTCTGTATGTTTTTATAGCTGGTTTTTAAAAAGCATAATATGCCTATAGCTGAAAAGGAAACAGGGCTGTTTAAGTCACTGACTTA
TGAGAAAGCAAAGCACTGGTACAGTTATTTAACAGGCATACACAAGCAGGGAAAAGATAATCCATTTAGATCTTTAATGCTTTGGAAATG
CGTGTAACAGTACTGCAATAATCACAGCTCTGGGAAAAACAACGAAACTTTCCCTTGTGGAGAGGAGGGATTTTCCTGCTCTATATAAGC
AACATATTTTTAGACATTAAAATATATATAATTTTGCAGGTAATTGTTGACTTTTTTAACTATATTAAGTGTTAAGCTGACAACTGTCAA
AGAAGACCATGTTGTAAAATAATTTGACTAAATAAATGGTTCCTTCTCTCAGTGCTGAGGACAGTTTTCTTATTTACCGCCCCCGTTAGG
TCAAAGGGTTTTCCCTGGGGAACTTTCCTATTTACTTCTTGCACTATCAAGAATTTTTCGAATGTACCTACTGCAGTACAGCAGAAGGTA
AAAAATCAGTGTGGTTTTTCATTGTTGTTGATGATGTTTGTAGTGTTTTTGTGTGTGTTATTTAAATCTTCCTCCAGCCTAAAAGGGTTT
TATAAAACAGCAGCTAAGGCCATGGATAAACCTGTATGTAAGGACTGGAGCAAAGCGAGCTGGTCTATCCAGACTGGTCTGTGAGATTTA
ACTCTGCAGCCTCCCCTGGGCACTTCAGACCCAGACGGCCACCTTCTGCCACTCCAGCAAAGAATAAGCGCCCTGCTTCCTTCAGGTCTC
AGACCAGGACTTTATGGCTCATGCAGATTTTTAAGGTCATTTTTCTTCCCAAGGAAGAAACTTGCCTCCAGTTCCTTCACTGTTAGGTAG
CTTATTTTCATTTTCTCTATTTTACAATGAAAAGAGTGAGACCTGGGAAGTCCTTGATTTGCAAGGAATTAGACTCACAGCATTGGTAAC
CCTAGAACCTTCTTAGGGTAACACTAAGTACCTTCTAGACAACATGTCTACCTAAATGAAATGGGATGTGTTTCGGAACATTTGTCTCCA
GTTTTTTTTTAATCTTGCACCCTGCCATTTAAAAAGATGTGTAAAGCACATATTCTCAACATATGCACATTGATTTATAAATCATATATA
CAAACTGTTACATTATTCTTCATATTAGAAAACAAATACAAAATAGAACATTTTAAATGGTGATATAAAAATAAATTGAAACTGAAATTC
T

>26186_26186_6_ELK1-FLI1_ELK1_chrX_47500631_ENST00000592066_FLI1_chr11_128680500_ENST00000281428_length(amino acids)=123AA_BP=
MNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAA
SQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY

--------------------------------------------------------------
>26186_26186_7_ELK1-FLI1_ELK1_chrX_47500631_ENST00000592066_FLI1_chr11_128680500_ENST00000344954_length(transcript)=2971nt_BP=310nt
CGCGTATGGAGCCCCCGCCCCCCGGAGCTGCCAACATTGCCAACGCCACCGCCACGCTACACACAGGTACCCCTGGGATGGCGTGAGCAC
TCCCCCAGCGATGGACCCATCTGTGACGCTGTGGCAGTTTCTGCTGCAGCTGCTGAGAGAGCAAGGCAATGGCCACATCATCTCCTGGAC
TTCACGGGATGGTGGTGAATTCAAGCTGGTGGATGCAGAGGAGGTGGCCCGGCTGTGGGGGCTACGCAAGAACAAGACCAACATGAATTA
CGACAAGCTCAGCCGGGCCTTGCGGTACTACTATGACAAGGCAAGCCCAACATGAATTACGACAAGCTGAGCCGGGCCCTCCGTTATTAC
TATGATAAAAACATTATGACCAAAGTGCACGGCAAAAGATATGCTTACAAATTTGACTTCCACGGCATTGCCCAGGCTCTGCAGCCACAT
CCGACCGAGTCGTCCATGTACAAGTACCCTTCTGACATCTCCTACATGCCTTCCTACCATGCCCACCAGCAGAAGGTGAACTTTGTCCCT
CCCCATCCATCCTCCATGCCTGTCACTTCCTCCAGCTTCTTTGGAGCCGCATCACAATACTGGACCTCCCCCACGGGGGGAATCTACCCC
AACCCCAACGTCCCCCGCCATCCTAACACCCACGTGCCTTCACACTTAGGCAGCTACTACTAGAAGCTTACTCATCAGTGGCCTTCTAGC
TGAAGCCCATCCTGCACACTTACTGGATGCTTTGGACTCAACAGGACATATGTGGCCTTGAAGGGAAGACAAAACTGGATGTTCTTTCTT
GTTGGATAGAACCTTTGTATTTGTTCTTTAAAAACATTTTTTTTAATGTTGGTAACTTTTGCTTCCTCTACCTGAACAAAGAGATGAATA
ATTCCATGGGCCAGTATGCCAGTTTGAATTCTCAGTCTCCTAGCATCTTGTGAGTTGCATATTAAGATTACTGGAATGGTTAAGTCATGG
TTCTGAGAAAGAAGCTGTACGTTTTCTTTATGTTTTTATGACCAAAGCAGTTTCTTGTCAATACACGGGGTTCAGTATGACACAGAATCA
TGGACTTAACCCGTCATGTTCTGGTTTGAGATTTAGTGACAAATAGAGGTGGGAAGCTTATAATCTAATTTTAGGAGGACCAAATTCAGT
GGATGGCAACTGGAACATTGATTGTAAGGCCAGTGAAGTTTTCACCCAACTGGAATTTGATGGAAAGAAGGTTTGTGTGTTTAAGACGCC
AAGGGCATTGCAGAATCCCTCTCAGTGGACAGTATGCACTCAGCTGACCACTCTCTCTAGAAATAGTCAAGATATGAACTAAGAAATTTT
AATGCAAATACATACATTCCTGAAAGACGGGGAATTAAATTACTAATTTTTTTTTTTTTTTAAATGATGACAGTGGTCCCAGAACTTGGA
AAAGTTGTAGGGATTTCTAAACTCAAGCAGATTCGCAAGTGCTGTGCGCTTGTCAGACCATCAGACCAGGGCCAACCAATCAGAAGGCAA
CTTACTGTATAAATTATGCAGAGTTATTTTCCTATATCTCACAGTATTAAAAATAAATAATTAAAAATTAAGAATAAATAAACGAGTTGA
CCTCGGTCACAAAAGCAGTTTTACTATCGAATCAATCGCTGTTATTTTTTTTAATGTAATTTGTACATCTTTTTTCAATCTGTACATTTG
GGCTGTCTGTATGTTTTTATAGCTGGTTTTTAAAAAGCATAATATGCCTATAGCTGAAAAGGAAACAGGGCTGTTTAAGTCACTGACTTA
TGAGAAAGCAAAGCACTGGTACAGTTATTTAACAGGCATACACAAGCAGGGAAAAGATAATCCATTTAGATCTTTAATGCTTTGGAAATG
CGTGTAACAGTACTGCAATAATCACAGCTCTGGGAAAAACAACGAAACTTTCCCTTGTGGAGAGGAGGGATTTTCCTGCTCTATATAAGC
AACATATTTTTAGACATTAAAATATATATAATTTTGCAGGTAATTGTTGACTTTTTTAACTATATTAAGTGTTAAGCTGACAACTGTCAA
AGAAGACCATGTTGTAAAATAATTTGACTAAATAAATGGTTCCTTCTCTCAGTGCTGAGGACAGTTTTCTTATTTACCGCCCCCGTTAGG
TCAAAGGGTTTTCCCTGGGGAACTTTCCTATTTACTTCTTGCACTATCAAGAATTTTTCGAATGTACCTACTGCAGTACAGCAGAAGGTA
AAAAATCAGTGTGGTTTTTCATTGTTGTTGATGATGTTTGTAGTGTTTTTGTGTGTGTTATTTAAATCTTCCTCCAGCCTAAAAGGGTTT
TATAAAACAGCAGCTAAGGCCATGGATAAACCTGTATGTAAGGACTGGAGCAAAGCGAGCTGGTCTATCCAGACTGGTCTGTGAGATTTA
ACTCTGCAGCCTCCCCTGGGCACTTCAGACCCAGACGGCCACCTTCTGCCACTCCAGCAAAGAATAAGCGCCCTGCTTCCTTCAGGTCTC
AGACCAGGACTTTATGGCTCATGCAGATTTTTAAGGTCATTTTTCTTCCCAAGGAAGAAACTTGCCTCCAGTTCCTTCACTGTTAGGTAG
CTTATTTTCATTTTCTCTATTTTACAATGAAAAGAGTGAGACCTGGGAAGTCCTTGATTTGCAAGGAATTAGACTCACAGCATTGGTAAC
CCTAGAACCTTCTTAGGGTAACACTAAGTACCTTCTAGACAACATGTCTACCTAAATGAAATGGGATGTGTTTCGGAACATTTGTCTCCA
GTTTTTTTTTAATCTTGCACCCTGCCATTTAAAAAGATGTGTAAAGCACATATTCTCAACATATGCACATTGATTTATAAATCATATATA
CAAACTGTTACATTATTCTTCATATTAGAAAACAAATACAAAATAGAACATTTTAAATGGTGATATAAAAATAAATTGAAACTGAAATTC
T

>26186_26186_7_ELK1-FLI1_ELK1_chrX_47500631_ENST00000592066_FLI1_chr11_128680500_ENST00000344954_length(amino acids)=123AA_BP=
MNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAA
SQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ELK1-FLI1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ELK1-FLI1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ELK1-FLI1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0279980Extra-osseous Ewing's sarcoma4ORPHANET
TgeneC0553580Ewings sarcoma3CTD_human;ORPHANET
TgeneC4479515BLEEDING DISORDER, PLATELET-TYPE, 213CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneC0684337Ewings sarcoma-primitive neuroectodermal tumor (PNET)2ORPHANET
TgeneC1956093Paris-Trousseau Thrombocytopenia2ORPHANET
TgeneC0023893Liver Cirrhosis, Experimental1CTD_human
TgeneC0025149Medulloblastoma1CTD_human
TgeneC0205833Medullomyoblastoma1CTD_human
TgeneC0278510Childhood Medulloblastoma1CTD_human
TgeneC0278876Adult Medulloblastoma1CTD_human
TgeneC0751291Desmoplastic Medulloblastoma1CTD_human
TgeneC0795841Jacobsen Distal 11q Deletion Syndrome1ORPHANET
TgeneC1275668Melanotic medulloblastoma1CTD_human