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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ERG-ZNRF3 (FusionGDB2 ID:HG2078TG84133)

Fusion Gene Summary for ERG-ZNRF3

check button Fusion gene summary
Fusion gene informationFusion gene name: ERG-ZNRF3
Fusion gene ID: hg2078tg84133
HgeneTgene
Gene symbol

ERG

ZNRF3

Gene ID

2078

84133

Gene nameETS transcription factor ERGzinc and ring finger 3
Synonymserg-3|p55BK747E2.3|RNF203
Cytomap('ERG')('ZNRF3')

21q22.2

22q12.1

Type of geneprotein-codingprotein-coding
Descriptiontranscriptional regulator ERGERG, ETS transcription factorFUS/ERG fusion proteinTMPRSS2/ERG fusionerythroblast transformation-specific transcription factor ERG variant 10ets-relatedtranscriptional regulator ERG (transforming protein ERG)v-ets avianE3 ubiquitin-protein ligase ZNRF3CTA-292E10.6RING finger protein 203RING-type E3 ubiquitin transferase ZNRF3novel C3HC4 type Zinc finger (ring finger)zinc/RING finger protein 3
Modification date2020032020200313
UniProtAcc

P11308

.
Ensembl transtripts involved in fusion geneENST00000398897, ENST00000485493, 
ENST00000398910, ENST00000417133, 
ENST00000442448, ENST00000398911, 
ENST00000398919, ENST00000288319, 
ENST00000398905, ENST00000398907, 
ENST00000429727, ENST00000453032, 
Fusion gene scores* DoF score19 X 16 X 5=152016 X 21 X 8=2688
# samples 3121
** MAII scorelog2(31/1520*10)=-2.29373120305671
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(21/2688*10)=-3.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ERG [Title/Abstract] AND ZNRF3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointERG(39947586)-ZNRF3(29383064), # samples:1
Anticipated loss of major functional domain due to fusion event.ERG-ZNRF3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ERG-ZNRF3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ERG-ZNRF3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ERG-ZNRF3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ERG-ZNRF3 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
ERG-ZNRF3 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ERG-ZNRF3 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
ERG-ZNRF3 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
ERG-ZNRF3 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneERG

GO:0045944

positive regulation of transcription by RNA polymerase II

18195090|23913826

TgeneZNRF3

GO:0016567

protein ubiquitination

22575959


check buttonFusion gene breakpoints across ERG (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ZNRF3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-J4-A83I-01AERGchr21

39947586

-ZNRF3chr22

29383064

+


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Fusion Gene ORF analysis for ERG-ZNRF3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000398897ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
5UTR-3CDSENST00000398897ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
5UTR-3CDSENST00000398897ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
5UTR-3CDSENST00000398897ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
5UTR-3CDSENST00000485493ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
5UTR-3CDSENST00000485493ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
5UTR-3CDSENST00000485493ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
5UTR-3CDSENST00000485493ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shiftENST00000398910ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shiftENST00000398910ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shiftENST00000398910ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shiftENST00000398910ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shiftENST00000417133ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shiftENST00000417133ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shiftENST00000417133ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shiftENST00000417133ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shiftENST00000442448ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shiftENST00000442448ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shiftENST00000442448ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shiftENST00000442448ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
In-frameENST00000398911ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
In-frameENST00000398911ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
In-frameENST00000398911ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
In-frameENST00000398911ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
In-frameENST00000398919ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
In-frameENST00000398919ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
In-frameENST00000398919ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
In-frameENST00000398919ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000288319ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000288319ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000288319ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000288319ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000398905ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000398905ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000398905ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000398905ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000398907ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000398907ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000398907ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000398907ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000429727ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000429727ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000429727ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000429727ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000453032ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000453032ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000453032ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000453032ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000398911ERGchr2139947586-ENST00000544604ZNRF3chr2229383064+65641881402698852
ENST00000398911ERGchr2139947586-ENST00000332811ZNRF3chr2229383064+65641881402698852
ENST00000398911ERGchr2139947586-ENST00000402174ZNRF3chr2229383064+27621881402698852
ENST00000398911ERGchr2139947586-ENST00000406323ZNRF3chr2229383064+30411881272697856
ENST00000398919ERGchr2139947586-ENST00000544604ZNRF3chr2229383064+67103342862844852
ENST00000398919ERGchr2139947586-ENST00000332811ZNRF3chr2229383064+67103342862844852
ENST00000398919ERGchr2139947586-ENST00000402174ZNRF3chr2229383064+29083342862844852
ENST00000398919ERGchr2139947586-ENST00000406323ZNRF3chr2229383064+31873342732843856

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000398911ENST00000544604ERGchr2139947586-ZNRF3chr2229383064+0.0020704270.9979296
ENST00000398911ENST00000332811ERGchr2139947586-ZNRF3chr2229383064+0.0020704270.9979296
ENST00000398911ENST00000402174ERGchr2139947586-ZNRF3chr2229383064+0.0325586270.9674414
ENST00000398911ENST00000406323ERGchr2139947586-ZNRF3chr2229383064+0.0135370010.986463
ENST00000398919ENST00000544604ERGchr2139947586-ZNRF3chr2229383064+0.0020166670.99798334
ENST00000398919ENST00000332811ERGchr2139947586-ZNRF3chr2229383064+0.0020166670.99798334
ENST00000398919ENST00000402174ERGchr2139947586-ZNRF3chr2229383064+0.0274257080.9725743
ENST00000398919ENST00000406323ERGchr2139947586-ZNRF3chr2229383064+0.0117305520.98826945

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Fusion Genomic Features for ERG-ZNRF3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ERGchr2139947585-ZNRF3chr2229383063+1.25E-070.9999999
ERGchr2139947585-ZNRF3chr2229383063+1.25E-070.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ERG-ZNRF3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr21:39947586/chr22:29383064)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ERG

P11308

.
FUNCTION: Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneZNRF3chr21:39947586chr22:29383064ENST0000033281109241_9360837.0Topological domainCytoplasmic
TgeneZNRF3chr21:39947586chr22:29383064ENST000003328110956_2190837.0Topological domainExtracellular
TgeneZNRF3chr21:39947586chr22:29383064ENST0000040217409241_9360837.0Topological domainCytoplasmic
TgeneZNRF3chr21:39947586chr22:29383064ENST000004021740956_2190837.0Topological domainExtracellular
TgeneZNRF3chr21:39947586chr22:29383064ENST0000040632308241_9360837.0Topological domainCytoplasmic
TgeneZNRF3chr21:39947586chr22:29383064ENST000004063230856_2190837.0Topological domainExtracellular
TgeneZNRF3chr21:39947586chr22:29383064ENST0000054460409241_936100937.0Topological domainCytoplasmic
TgeneZNRF3chr21:39947586chr22:29383064ENST0000033281109220_2400837.0TransmembraneHelical
TgeneZNRF3chr21:39947586chr22:29383064ENST0000040217409220_2400837.0TransmembraneHelical
TgeneZNRF3chr21:39947586chr22:29383064ENST0000040632308220_2400837.0TransmembraneHelical
TgeneZNRF3chr21:39947586chr22:29383064ENST0000054460409220_240100937.0TransmembraneHelical
TgeneZNRF3chr21:39947586chr22:29383064ENST0000033281109293_3340837.0Zinc fingerRING-type%3B atypical
TgeneZNRF3chr21:39947586chr22:29383064ENST0000040217409293_3340837.0Zinc fingerRING-type%3B atypical
TgeneZNRF3chr21:39947586chr22:29383064ENST0000040632308293_3340837.0Zinc fingerRING-type%3B atypical
TgeneZNRF3chr21:39947586chr22:29383064ENST0000054460409293_334100937.0Zinc fingerRING-type%3B atypical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneERGchr21:39947586chr22:29383064ENST00000288319-110311_3910480.0DNA bindingETS
HgeneERGchr21:39947586chr22:29383064ENST00000398897-29311_3910364.0DNA bindingETS
HgeneERGchr21:39947586chr22:29383064ENST00000398911-210311_39113463.0DNA bindingETS
HgeneERGchr21:39947586chr22:29383064ENST00000398919-312311_39113487.0DNA bindingETS
HgeneERGchr21:39947586chr22:29383064ENST00000417133-312311_39113487.0DNA bindingETS
HgeneERGchr21:39947586chr22:29383064ENST00000442448-311311_39113463.0DNA bindingETS
HgeneERGchr21:39947586chr22:29383064ENST00000453032-19311_3910388.0DNA bindingETS
HgeneERGchr21:39947586chr22:29383064ENST00000288319-110113_1990480.0DomainPNT
HgeneERGchr21:39947586chr22:29383064ENST00000398897-29113_1990364.0DomainPNT
HgeneERGchr21:39947586chr22:29383064ENST00000398911-210113_19913463.0DomainPNT
HgeneERGchr21:39947586chr22:29383064ENST00000398919-312113_19913487.0DomainPNT
HgeneERGchr21:39947586chr22:29383064ENST00000417133-312113_19913487.0DomainPNT
HgeneERGchr21:39947586chr22:29383064ENST00000442448-311113_19913463.0DomainPNT
HgeneERGchr21:39947586chr22:29383064ENST00000453032-19113_1990388.0DomainPNT
TgeneZNRF3chr21:39947586chr22:29383064ENST000005446040956_219100937.0Topological domainExtracellular


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Fusion Gene Sequence for ERG-ZNRF3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>27381_27381_1_ERG-ZNRF3_ERG_chr21_39947586_ENST00000398911_ZNRF3_chr22_29383064_ENST00000332811_length(transcript)=6564nt_BP=188nt
GTTATTCCAGGATCTTTGGAGACCCGAGGAAAGCCGTGTTGACCAAAAGCAAGACAAATGACTCACAGAGAAAAAAGATGGCAGAACCAA
GGGCAACTAAAGCCGTCAGGTTCTGAACAGCTGGTAGATGGGCTGGCTTACTGAAGGACATGATTCAGACTGTCCCGGACCCAGCAGCTC
ATATCAAGATGCACCCACTGGGCCTATGTAATAACAATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAAC
AGCCAGAATTGGACCCGAAACCATGCCTCACTGTCCTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATG
TGTCTGAAAACCCAGAAGCTATTGATCAGCTGAACCAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATG
CCATTAAGCTGATGAACATCGTCAACAAGCAGAAAGTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTG
ACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTCTCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTC
AGAATTCCATGAACAGGCTGGCTGTGCAGGCTCTAGAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGA
GCTGTGGGGCCCTGGACACACTCAGCAGCAGCTCCACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGG
TCATCCCCTGTACTCACCGGTTTCACAGGAAGTGCGTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCA
TAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTGGAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATT
ACCCCGGCCGCGTGCACAGGACCAACGCCATCCCAGCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGA
CCATGGACCGGCACGGGGAGCAGAGCCTCTATTCCCCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCC
TGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCCTACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCA
AGGCAGCTTGCTTCTCCCAGTATGAGACCATGTACCAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCAC
CTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTTCCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGC
CCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTCAGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAG
GCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAGTGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGG
GCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCCCTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCA
GTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGACCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACA
GTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGCCCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACA
GCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAATAGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCA
GGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCGTGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAG
CTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTCTACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCT
TGTACGGCCTTCACCCCGACCATTTGCCCAGGACAGATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGG
CCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACTGAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCT
GCTACCCCGGGGCCCGGGACCTGAGCCAGCGCATCCCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAG
GGACCCACAGCCTCGGCTCCTGGGGTGGGACGCGAGGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGC
GGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGGCCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCC
TCCAGGACACTCAGGAGTCCAGCACCACTGCCACTGAGGCTGCAGGACCGAGATCTCACTCAGCAGACAGCAGCAGCCCGGGAGCCTGAG
CTCAGGAGGAACTCTTACCTGGAAATTGGGAACTGTATGGAGACTCCAAACTGACTTCTTTCAAAAAACAAAAACAAAAAATTTTTTTAG
CTTTGACAAACACACAAAAGTGGTAATAAAGAGAGCCCTCCTTGTCAACCCAAAATGTGAGCCCCCTGTGGCAAAACCACCCCCTACCCC
ATTAACAAATCAACAGACAAAATTCTCCGAGTCCTTTGCCTCTTTTGATAACATGTTGTTCTGTTTTGTAAAGTGTGTGTGCTTGGGGTT
CCGAGGTGTGGGATTGAGTTCTCTGCTTTGTTTTTTTTTAAGATATTGTATGTAAATGTAAAAAGTTATTTAAATATATATTTTAAAGAA
CCCTAACTGCCAACTTTTGCTGAAAAAGAAAAAAAAATCACTGCTGCATTAAATGAACCACATCATGTGTAGATACTGTTGTCTCCCTGA
AGGGAGCTCAGGCCTTTGAAAAGCTCAGGGCTTCACCTGCCTTAGAAAATGAACCAGAAACTTGAAGTAAAGCTAGTTGATAGGGGTACA
GGCTCTGAGGAGCAGTGCAAAACTGCCTCTTTCTTTCTCGTGGCAAATCCCAATGTACACGATTTCAGGTCTCAGACGCCATGCCTCTCC
AGCCCACGCCTTTAGGCAGGTGATGGCAGCAGCTAGGAATAGGGTGTACATGATCCACAGCCCTGCGGAGCCAGGTCAAGCCGCTGCTAT
GAAAGCTCCAGGGTGATGGGGACGATTCTGCCCAGTGTCCTCAGTCTGTCCCCTCAGGTCATGGTCCCAAGTGAAATGACAGAGTTCACA
GCCCTGGTCTTGGCTGAGGTCCAGGTCATAGTAAGGGCATGTTCTTGGGGCCCTCGACCTGAACTCTGACCCTCCGGGCAGGGAAGAGGA
GGTTGTCCCCTTTGGTTGTCCTGGCTTTGGAGTCCTTTGCAAAAATATTTTGGGCCCCCTGCCACTGGCTGCAGAAATGGCTCGACGGGG
TGTGTGGGGACAGACACCCAGAAGGAATGTACTTTTGTGGCCTTGGTGTCCGATGGGGCTGGGGGAGAGTGCTCTCCACTGACCCAGCAG
CACACCCATGTGCAGTGCGCCTGCATCTGTGTGGGGGCAGCCACACCCCTTGGCTGCTGCTTCCTTGGGCTGCCTTTCTGGGGGCATGTG
ACTGGACCTACGAGGTCTGCACTGAGCTCCATTTGAATGATACCTTTCCTATCCCATTTCCCCCACGGAAGCACCGCTTCAGGGTTATTC
AGTCCTCTGCCTCATGGCTGAAATTGCTCATCTCGTCTGCAGATGTCTACTATCCTGTCTACCTAATGCACTATTATGTATTGATTCTCC
ATGAGACAGAGAGAGAGAGAGACTATCAGATAGTTTACACCCAAAGGGTAGGTTTTTGTATATTTTTCCAGCCTTTTTTATTAAGGGGAA
GGGGAGAGTTTAAAAACCCAAACCGTTGTGGTTTTAAGGTGTTTCATTTTTAAAAGGGAGAGAGAATCTATTTAAAGCTATTTCAGATCA
GGGATTGTCATCCTTTTTTGTCCAATGTATTCCTTGTTCTTTAAAAAAATTTTTTTTAGAGGAAACTAATATTAGTCTTTGTGTTCACTA
ACTCTTCTGGTCACTTGTATTTATTTATTCATTCATTCATCAGATATTTGTTGCCATCTGAAAGAACTGGCCCAGTGGGTCTGAAAGCTC
GCTTGAGAATAGGAAACTTGAGACCTGGCCCCCTGTGGGTAGGAGAACAAGGACCACCTGGGTTCTCCAGTCTTGAACGAGAATCTCACT
CTTATCAGAATGTTTTTCTTAACCTCAGCGTATGATGAGGAAATTTACTTATCTCTAGCTAGGATTTGACAAATTCCAACATCAAATGAT
CAAAACATTTGCCACTGAGGCTTCACTGGTGAGATCCGTTCTCCGTCCTCGGGTGCAGTCCCTTGGGGGCTGCTCCTCGGACTGCGCCCC
GCACACCTGTTATCGAGGGTGTGAGAAGCGCCTAAGCTGGTGACATGTGATCTGGGACGCCTTCATTTCTCGGGCCAGGAGTAGCAGCTG
CTAAGGACAGCAGCTTGCATTGCGTGGTTTTAGGGAAGCAGGGTCTGGCTTTTAATATGAACTGCAAAAAGCAGCTTCTCACTGATATTT
TTTTGTTGTTGTTTCTGGGGGGTTTTTTTGTTTTGTTTTTAATGCCTTTGAGTGCATATTTTCTTCCTCGTCTGAAACCGAACTCCCAAA
GTGGCTTTCTTTAGCCCTGGCTGGAAAACCACCTCTCAATAGCCTTAAGCAATAAATAGATGAGTAGAGAATGTGGCTTCAACTGGGCTT
ATTAAAGTAAGTGTGTCTAGTTTTCACTTGAACAAGTGATAGCTGCAGATGGCGAAAGAAACCCATTTAATTTTTGTAGCTTACAGGTGG
TAGAAACAAAAATGCAATTTTAAAACCTTAAATACCAAATACCAACCATTGCCTTTTTTTTTTTTGAGATGGAATTTTGCTCTTGTCACC
CAGGCTGGAGTGCAATGGCGCGATCTCACCTCACTGCAACCTCTGCCTCCCGGGTCCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGC
TGGGATTACAGGCATGCGCCACCACACCCAGCTAATTTTGTATTTTTGGTAGAGACAGGGTATCTCCATGTTGGTCAGGCTGGTCTTGGA
TTCCCGACCTCAGGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCTGCCCAGCAATACCAACC
ATTGTCTTTTAAATTCGTGTTGGCTTCTCAGACAGGGAGATCACTGGAATAAAATAACCGATGGTCTTATTTTGTCACACGTAAATCAAA
AGAAATGTCCTCTTTGAAGTTGTAAGACTCCACCAATGACAGACACCCTTTTCGGTGGACTCTGAGTGGTGTGTAGTGGTTTTATAGCCA
TGGAAACTAGGAGTATCTCACTTTCCACTGAGAACCCCTGCCCCCAATCCCTCTAAGTTGGGGTGTGGCAGTTGGGCAGGGTCAAGTGAC
CCAGCCCTGGCTGTAGGACAGCCATATACAGTGAAGAGTTCTAGAACCAGCTAAAAATGGAAGTTTGGGTGTTTACCAACAAGGTACCTC
TTTATGGATGCAGCCCCAGTAAGCTGGCTTTAACTCTCAGCTCCTTCCCTGTCTCCTCCTAATCCAAGCCCTTTTATAAAATAAAGCCCC
TTCTGTCCCACTGCTCACATACTTATGTGCTGCTAGTCTCTACTCGAAGTTCGTGCAGGACTAATGCTTTTAAAATGAGGTCTAAAAAAT
AATTACTAGTCGAGACTATTATTCTTTAAACAGAACTGCCTTTTTCTACTCTTTATGTAAACTCTTTCTATTGTGTTGGTCTAACAAGGC
ACTATTTTAAAATTTTTTAATTTTTCCCATAGCACTTAAAAGAGATTTTGTAAAGACCTTGCTGTAAAGATTTTGTAATAAAATGGTCTA
AGGGCTCTTTTTCCAACATTACCATTTTTAAAAAATGTTTTAAAAGCTAGAAGACAACTTATGTATATTCTGTATATGTATAGCAGCACA
TTTCATTTATGGAAATATGTTCTCAGAATATTTATTTACTAATATATTTATCTTAAGCCATGTCTTATGTTGAGAGTGTGACATTGTTGG
AATAATCATTGAAAATGACTAACACAAGACCCTGTAAATACATGATAATTGCACACAGATTTTACATATTTGCAGACCAAAAATGATTTA

>27381_27381_1_ERG-ZNRF3_ERG_chr21_39947586_ENST00000398911_ZNRF3_chr22_29383064_ENST00000332811_length(amino acids)=852AA_BP=16
MKDMIQTVPDPAAHIKMHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSED
PLKRPVVYVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQALEKMET
RKFNSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVETSNL
SRGRQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLYSPQTPAYIRSYPPLHLDHSLAAHRCGLEHRAYSPAH
PFRRPKLSGRSFSKAACFSQYETMYQHYYFQGLSYPEQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSFSCYHG
HRSVCSGYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDYDPFIYRSRSPCRASEAGGSGSSGRGPALCF
EGSPPPEELPAVHSHGAGRGEPWPGPASPSGDQVSTCSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPSCACCC
EPQPSPAGPSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPCCFYEEKQVARGGGGGSGCYTEDYSV
SVQYTLTEEPPPGCYPGARDLSQRIPIIPEDVDCDLGLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLRPGCPP

--------------------------------------------------------------
>27381_27381_2_ERG-ZNRF3_ERG_chr21_39947586_ENST00000398911_ZNRF3_chr22_29383064_ENST00000402174_length(transcript)=2762nt_BP=188nt
GTTATTCCAGGATCTTTGGAGACCCGAGGAAAGCCGTGTTGACCAAAAGCAAGACAAATGACTCACAGAGAAAAAAGATGGCAGAACCAA
GGGCAACTAAAGCCGTCAGGTTCTGAACAGCTGGTAGATGGGCTGGCTTACTGAAGGACATGATTCAGACTGTCCCGGACCCAGCAGCTC
ATATCAAGATGCACCCACTGGGCCTATGTAATAACAATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAAC
AGCCAGAATTGGACCCGAAACCATGCCTCACTGTCCTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATG
TGTCTGAAAACCCAGAAGCTATTGATCAGCTGAACCAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATG
CCATTAAGCTGATGAACATCGTCAACAAGCAGAAAGTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTG
ACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTCTCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTC
AGAATTCCATGAACAGGCTGGCTGTGCAGGCTCTAGAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGA
GCTGTGGGGCCCTGGACACACTCAGCAGCAGCTCCACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGG
TCATCCCCTGTACTCACCGGTTTCACAGGAAGTGCGTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCA
TAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTGGAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATT
ACCCCGGCCGCGTGCACAGGACCAACGCCATCCCAGCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGA
CCATGGACCGGCACGGGGAGCAGAGCCTCTATTCCCCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCC
TGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCCTACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCA
AGGCAGCTTGCTTCTCCCAGTATGAGACCATGTACCAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCAC
CTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTTCCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGC
CCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTCAGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAG
GCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAGTGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGG
GCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCCCTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCA
GTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGACCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACA
GTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGCCCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACA
GCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAATAGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCA
GGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCGTGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAG
CTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTCTACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCT
TGTACGGCCTTCACCCCGACCATTTGCCCAGGACAGATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGG
CCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACTGAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCT
GCTACCCCGGGGCCCGGGACCTGAGCCAGCGCATCCCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAG
GGACCCACAGCCTCGGCTCCTGGGGTGGGACGCGAGGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGC
GGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGGCCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCC
TCCAGGACACTCAGGAGTCCAGCACCACTGCCACTGAGGCTGCAGGACCGAGATCTCACTCAGCAGACAGCAGCAGCCCGGGAGCCTGAG

>27381_27381_2_ERG-ZNRF3_ERG_chr21_39947586_ENST00000398911_ZNRF3_chr22_29383064_ENST00000402174_length(amino acids)=852AA_BP=16
MKDMIQTVPDPAAHIKMHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSED
PLKRPVVYVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQALEKMET
RKFNSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVETSNL
SRGRQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLYSPQTPAYIRSYPPLHLDHSLAAHRCGLEHRAYSPAH
PFRRPKLSGRSFSKAACFSQYETMYQHYYFQGLSYPEQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSFSCYHG
HRSVCSGYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDYDPFIYRSRSPCRASEAGGSGSSGRGPALCF
EGSPPPEELPAVHSHGAGRGEPWPGPASPSGDQVSTCSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPSCACCC
EPQPSPAGPSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPCCFYEEKQVARGGGGGSGCYTEDYSV
SVQYTLTEEPPPGCYPGARDLSQRIPIIPEDVDCDLGLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLRPGCPP

--------------------------------------------------------------
>27381_27381_3_ERG-ZNRF3_ERG_chr21_39947586_ENST00000398911_ZNRF3_chr22_29383064_ENST00000406323_length(transcript)=3041nt_BP=188nt
GTTATTCCAGGATCTTTGGAGACCCGAGGAAAGCCGTGTTGACCAAAAGCAAGACAAATGACTCACAGAGAAAAAAGATGGCAGAACCAA
GGGCAACTAAAGCCGTCAGGTTCTGAACAGCTGGTAGATGGGCTGGCTTACTGAAGGACATGATTCAGACTGTCCCGGACCCAGCAGCTC
ATATCAAGTGCACCCACTGGGCCTATGTAATAACAATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAACA
GCCAGAATTGGACCCGAAACCATGCCTCACTGTCCTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATGT
GTCTGAAAACCCAGAAGCTATTGATCAGCTGAACCAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATGC
CATTAAGCTGATGAACATCGTCAACAAGCAGAAAGTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTGA
CATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTCTCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTCA
GAATTCCATGAACAGGCTGGCTGTGCAGGCTCTAGAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGAG
CTGTGGGGCCCTGGACACACTCAGCAGCAGCTCCACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGGT
CATCCCCTGTACTCACCGGTTTCACAGGAAGTGCGTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCAT
AGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTGGAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATTA
CCCCGGCCGCGTGCACAGGACCAACGCCATCCCAGCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGAC
CATGGACCGGCACGGGGAGCAGAGCCTCTATTCCCCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCCT
GGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCCTACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAA
GGCAGCTTGCTTCTCCCAGTATGAGACCATGTACCAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCACC
TAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTTCCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGCC
CTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTCAGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAGG
CAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAGTGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGGG
CGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCCCTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCAG
TGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGACCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACAG
TCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGCCCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACAG
CAGCAACTCCTCCCTGGAGCACAGGGGGCCCAATAGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCAG
GAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCGTGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGC
TGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTCTACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTT
GTACGGCCTTCACCCCGACCATTTGCCCAGGACAGATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGGC
CCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACTGAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCTG
CTACCCCGGGGCCCGGGACCTGAGCCAGCGCATCCCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAGG
GACCCACAGCCTCGGCTCCTGGGGTGGGACGCGAGGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGCG
GGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGGCCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCCT
CCAGGACACTCAGGAGTCCAGCACCACTGCCACTGAGGCTGCAGGACCGAGATCTCACTCAGCAGACAGCAGCAGCCCGGGAGCCTGAGC
TCAGGAGGAACTCTTACCTGGAAATTGGGAACTGTATGGAGACTCCAAACTGACTTCTTTCAAAAAACAAAAACAAAAAATTTTTTTAGC
TTTGACAAACACACAAAAGTGGTAATAAAGAGAGCCCTCCTTGTCAACCCAAAATGTGAGCCCCCTGTGGCAAAACCACCCCCTACCCCA
TTAACAAATCAACAGACAAAATTCTCCGAGTCCTTTGCCTCTTTTGATAACATGTTGTTCTGTTTTGTAAAGTGTGTGTGCTTGGGGTTC

>27381_27381_3_ERG-ZNRF3_ERG_chr21_39947586_ENST00000398911_ZNRF3_chr22_29383064_ENST00000406323_length(amino acids)=856AA_BP=21
MGWLTEGHDSDCPGPSSSYQVHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQ
GSEDPLKRPVVYVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQALE
KMETRKFNSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVE
TSNLSRGRQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLYSPQTPAYIRSYPPLHLDHSLAAHRCGLEHRAY
SPAHPFRRPKLSGRSFSKAACFSQYETMYQHYYFQGLSYPEQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSFS
CYHGHRSVCSGYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDYDPFIYRSRSPCRASEAGGSGSSGRGP
ALCFEGSPPPEELPAVHSHGAGRGEPWPGPASPSGDQVSTCSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPSC
ACCCEPQPSPAGPSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPCCFYEEKQVARGGGGGSGCYTE
DYSVSVQYTLTEEPPPGCYPGARDLSQRIPIIPEDVDCDLGLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLRP

--------------------------------------------------------------
>27381_27381_4_ERG-ZNRF3_ERG_chr21_39947586_ENST00000398911_ZNRF3_chr22_29383064_ENST00000544604_length(transcript)=6564nt_BP=188nt
GTTATTCCAGGATCTTTGGAGACCCGAGGAAAGCCGTGTTGACCAAAAGCAAGACAAATGACTCACAGAGAAAAAAGATGGCAGAACCAA
GGGCAACTAAAGCCGTCAGGTTCTGAACAGCTGGTAGATGGGCTGGCTTACTGAAGGACATGATTCAGACTGTCCCGGACCCAGCAGCTC
ATATCAAGATGCACCCACTGGGCCTATGTAATAACAATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAAC
AGCCAGAATTGGACCCGAAACCATGCCTCACTGTCCTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATG
TGTCTGAAAACCCAGAAGCTATTGATCAGCTGAACCAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATG
CCATTAAGCTGATGAACATCGTCAACAAGCAGAAAGTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTG
ACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTCTCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTC
AGAATTCCATGAACAGGCTGGCTGTGCAGGCTCTAGAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGA
GCTGTGGGGCCCTGGACACACTCAGCAGCAGCTCCACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGG
TCATCCCCTGTACTCACCGGTTTCACAGGAAGTGCGTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCA
TAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTGGAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATT
ACCCCGGCCGCGTGCACAGGACCAACGCCATCCCAGCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGA
CCATGGACCGGCACGGGGAGCAGAGCCTCTATTCCCCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCC
TGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCCTACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCA
AGGCAGCTTGCTTCTCCCAGTATGAGACCATGTACCAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCAC
CTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTTCCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGC
CCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTCAGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAG
GCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAGTGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGG
GCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCCCTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCA
GTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGACCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACA
GTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGCCCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACA
GCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAATAGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCA
GGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCGTGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAG
CTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTCTACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCT
TGTACGGCCTTCACCCCGACCATTTGCCCAGGACAGATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGG
CCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACTGAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCT
GCTACCCCGGGGCCCGGGACCTGAGCCAGCGCATCCCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAG
GGACCCACAGCCTCGGCTCCTGGGGTGGGACGCGAGGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGC
GGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGGCCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCC
TCCAGGACACTCAGGAGTCCAGCACCACTGCCACTGAGGCTGCAGGACCGAGATCTCACTCAGCAGACAGCAGCAGCCCGGGAGCCTGAG
CTCAGGAGGAACTCTTACCTGGAAATTGGGAACTGTATGGAGACTCCAAACTGACTTCTTTCAAAAAACAAAAACAAAAAATTTTTTTAG
CTTTGACAAACACACAAAAGTGGTAATAAAGAGAGCCCTCCTTGTCAACCCAAAATGTGAGCCCCCTGTGGCAAAACCACCCCCTACCCC
ATTAACAAATCAACAGACAAAATTCTCCGAGTCCTTTGCCTCTTTTGATAACATGTTGTTCTGTTTTGTAAAGTGTGTGTGCTTGGGGTT
CCGAGGTGTGGGATTGAGTTCTCTGCTTTGTTTTTTTTTAAGATATTGTATGTAAATGTAAAAAGTTATTTAAATATATATTTTAAAGAA
CCCTAACTGCCAACTTTTGCTGAAAAAGAAAAAAAAATCACTGCTGCATTAAATGAACCACATCATGTGTAGATACTGTTGTCTCCCTGA
AGGGAGCTCAGGCCTTTGAAAAGCTCAGGGCTTCACCTGCCTTAGAAAATGAACCAGAAACTTGAAGTAAAGCTAGTTGATAGGGGTACA
GGCTCTGAGGAGCAGTGCAAAACTGCCTCTTTCTTTCTCGTGGCAAATCCCAATGTACACGATTTCAGGTCTCAGACGCCATGCCTCTCC
AGCCCACGCCTTTAGGCAGGTGATGGCAGCAGCTAGGAATAGGGTGTACATGATCCACAGCCCTGCGGAGCCAGGTCAAGCCGCTGCTAT
GAAAGCTCCAGGGTGATGGGGACGATTCTGCCCAGTGTCCTCAGTCTGTCCCCTCAGGTCATGGTCCCAAGTGAAATGACAGAGTTCACA
GCCCTGGTCTTGGCTGAGGTCCAGGTCATAGTAAGGGCATGTTCTTGGGGCCCTCGACCTGAACTCTGACCCTCCGGGCAGGGAAGAGGA
GGTTGTCCCCTTTGGTTGTCCTGGCTTTGGAGTCCTTTGCAAAAATATTTTGGGCCCCCTGCCACTGGCTGCAGAAATGGCTCGACGGGG
TGTGTGGGGACAGACACCCAGAAGGAATGTACTTTTGTGGCCTTGGTGTCCGATGGGGCTGGGGGAGAGTGCTCTCCACTGACCCAGCAG
CACACCCATGTGCAGTGCGCCTGCATCTGTGTGGGGGCAGCCACACCCCTTGGCTGCTGCTTCCTTGGGCTGCCTTTCTGGGGGCATGTG
ACTGGACCTACGAGGTCTGCACTGAGCTCCATTTGAATGATACCTTTCCTATCCCATTTCCCCCACGGAAGCACCGCTTCAGGGTTATTC
AGTCCTCTGCCTCATGGCTGAAATTGCTCATCTCGTCTGCAGATGTCTACTATCCTGTCTACCTAATGCACTATTATGTATTGATTCTCC
ATGAGACAGAGAGAGAGAGAGACTATCAGATAGTTTACACCCAAAGGGTAGGTTTTTGTATATTTTTCCAGCCTTTTTTATTAAGGGGAA
GGGGAGAGTTTAAAAACCCAAACCGTTGTGGTTTTAAGGTGTTTCATTTTTAAAAGGGAGAGAGAATCTATTTAAAGCTATTTCAGATCA
GGGATTGTCATCCTTTTTTGTCCAATGTATTCCTTGTTCTTTAAAAAAATTTTTTTTAGAGGAAACTAATATTAGTCTTTGTGTTCACTA
ACTCTTCTGGTCACTTGTATTTATTTATTCATTCATTCATCAGATATTTGTTGCCATCTGAAAGAACTGGCCCAGTGGGTCTGAAAGCTC
GCTTGAGAATAGGAAACTTGAGACCTGGCCCCCTGTGGGTAGGAGAACAAGGACCACCTGGGTTCTCCAGTCTTGAACGAGAATCTCACT
CTTATCAGAATGTTTTTCTTAACCTCAGCGTATGATGAGGAAATTTACTTATCTCTAGCTAGGATTTGACAAATTCCAACATCAAATGAT
CAAAACATTTGCCACTGAGGCTTCACTGGTGAGATCCGTTCTCCGTCCTCGGGTGCAGTCCCTTGGGGGCTGCTCCTCGGACTGCGCCCC
GCACACCTGTTATCGAGGGTGTGAGAAGCGCCTAAGCTGGTGACATGTGATCTGGGACGCCTTCATTTCTCGGGCCAGGAGTAGCAGCTG
CTAAGGACAGCAGCTTGCATTGCGTGGTTTTAGGGAAGCAGGGTCTGGCTTTTAATATGAACTGCAAAAAGCAGCTTCTCACTGATATTT
TTTTGTTGTTGTTTCTGGGGGGTTTTTTTGTTTTGTTTTTAATGCCTTTGAGTGCATATTTTCTTCCTCGTCTGAAACCGAACTCCCAAA
GTGGCTTTCTTTAGCCCTGGCTGGAAAACCACCTCTCAATAGCCTTAAGCAATAAATAGATGAGTAGAGAATGTGGCTTCAACTGGGCTT
ATTAAAGTAAGTGTGTCTAGTTTTCACTTGAACAAGTGATAGCTGCAGATGGCGAAAGAAACCCATTTAATTTTTGTAGCTTACAGGTGG
TAGAAACAAAAATGCAATTTTAAAACCTTAAATACCAAATACCAACCATTGCCTTTTTTTTTTTTGAGATGGAATTTTGCTCTTGTCACC
CAGGCTGGAGTGCAATGGCGCGATCTCACCTCACTGCAACCTCTGCCTCCCGGGTCCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGC
TGGGATTACAGGCATGCGCCACCACACCCAGCTAATTTTGTATTTTTGGTAGAGACAGGGTATCTCCATGTTGGTCAGGCTGGTCTTGGA
TTCCCGACCTCAGGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCTGCCCAGCAATACCAACC
ATTGTCTTTTAAATTCGTGTTGGCTTCTCAGACAGGGAGATCACTGGAATAAAATAACCGATGGTCTTATTTTGTCACACGTAAATCAAA
AGAAATGTCCTCTTTGAAGTTGTAAGACTCCACCAATGACAGACACCCTTTTCGGTGGACTCTGAGTGGTGTGTAGTGGTTTTATAGCCA
TGGAAACTAGGAGTATCTCACTTTCCACTGAGAACCCCTGCCCCCAATCCCTCTAAGTTGGGGTGTGGCAGTTGGGCAGGGTCAAGTGAC
CCAGCCCTGGCTGTAGGACAGCCATATACAGTGAAGAGTTCTAGAACCAGCTAAAAATGGAAGTTTGGGTGTTTACCAACAAGGTACCTC
TTTATGGATGCAGCCCCAGTAAGCTGGCTTTAACTCTCAGCTCCTTCCCTGTCTCCTCCTAATCCAAGCCCTTTTATAAAATAAAGCCCC
TTCTGTCCCACTGCTCACATACTTATGTGCTGCTAGTCTCTACTCGAAGTTCGTGCAGGACTAATGCTTTTAAAATGAGGTCTAAAAAAT
AATTACTAGTCGAGACTATTATTCTTTAAACAGAACTGCCTTTTTCTACTCTTTATGTAAACTCTTTCTATTGTGTTGGTCTAACAAGGC
ACTATTTTAAAATTTTTTAATTTTTCCCATAGCACTTAAAAGAGATTTTGTAAAGACCTTGCTGTAAAGATTTTGTAATAAAATGGTCTA
AGGGCTCTTTTTCCAACATTACCATTTTTAAAAAATGTTTTAAAAGCTAGAAGACAACTTATGTATATTCTGTATATGTATAGCAGCACA
TTTCATTTATGGAAATATGTTCTCAGAATATTTATTTACTAATATATTTATCTTAAGCCATGTCTTATGTTGAGAGTGTGACATTGTTGG
AATAATCATTGAAAATGACTAACACAAGACCCTGTAAATACATGATAATTGCACACAGATTTTACATATTTGCAGACCAAAAATGATTTA

>27381_27381_4_ERG-ZNRF3_ERG_chr21_39947586_ENST00000398911_ZNRF3_chr22_29383064_ENST00000544604_length(amino acids)=852AA_BP=16
MKDMIQTVPDPAAHIKMHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSED
PLKRPVVYVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQALEKMET
RKFNSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVETSNL
SRGRQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLYSPQTPAYIRSYPPLHLDHSLAAHRCGLEHRAYSPAH
PFRRPKLSGRSFSKAACFSQYETMYQHYYFQGLSYPEQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSFSCYHG
HRSVCSGYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDYDPFIYRSRSPCRASEAGGSGSSGRGPALCF
EGSPPPEELPAVHSHGAGRGEPWPGPASPSGDQVSTCSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPSCACCC
EPQPSPAGPSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPCCFYEEKQVARGGGGGSGCYTEDYSV
SVQYTLTEEPPPGCYPGARDLSQRIPIIPEDVDCDLGLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLRPGCPP

--------------------------------------------------------------
>27381_27381_5_ERG-ZNRF3_ERG_chr21_39947586_ENST00000398919_ZNRF3_chr22_29383064_ENST00000332811_length(transcript)=6710nt_BP=334nt
GCTGAGCCCGTCGGCGCCGAGGGAGTTAGTGCGACCCGGCTCGGCGCGCACGGCCAAGGCACGCGCGCTGGCACACGCGGGCGCGGACAC
GCGCGGACACACACGTGCGGGACACGCCCTCCCCCGACGGCGGCGCTAACCTCTCGGTTATTCCAGGATCTTTGGAGACCCGAGGAAAGC
CGTGTTGACCAAAAGCAAGACAAATGACTCACAGAGAAAAAAGATGGCAGAACCAAGGGCAACTAAAGCCGTCAGGTTCTGAACAGCTGG
TAGATGGGCTGGCTTACTGAAGGACATGATTCAGACTGTCCCGGACCCAGCAGCTCATATCAAGATGCACCCACTGGGCCTATGTAATAA
CAATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAACAGCCAGAATTGGACCCGAAACCATGCCTCACTGT
CCTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATGTGTCTGAAAACCCAGAAGCTATTGATCAGCTGAA
CCAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATGCCATTAAGCTGATGAACATCGTCAACAAGCAGAA
AGTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTGACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGT
CTCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTCAGAATTCCATGAACAGGCTGGCTGTGCAGGCTCT
AGAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGAGCTGTGGGGCCCTGGACACACTCAGCAGCAGCTC
CACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGGTCATCCCCTGTACTCACCGGTTTCACAGGAAGTG
CGTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCATAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGT
GGAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATTACCCCGGCCGCGTGCACAGGACCAACGCCATCCC
AGCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGACCATGGACCGGCACGGGGAGCAGAGCCTCTATTC
CCCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCCTGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGC
CTACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAAGGCAGCTTGCTTCTCCCAGTATGAGACCATGTA
CCAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCACCTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTT
TCCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGCCCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTT
CAGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAGGCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCA
GTGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGGGCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTC
CCTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCAGTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGG
ACCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACAGTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGG
CCCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACAGCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAA
TAGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCAGGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTC
GTGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGCTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCT
CTACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTTGTACGGCCTTCACCCCGACCATTTGCCCAGGAC
AGATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGGCCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACAC
TGAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCTGCTACCCCGGGGCCCGGGACCTGAGCCAGCGCAT
CCCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAGGGACCCACAGCCTCGGCTCCTGGGGTGGGACGCG
AGGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGCGGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCG
GCCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCCTCCAGGACACTCAGGAGTCCAGCACCACTGCCAC
TGAGGCTGCAGGACCGAGATCTCACTCAGCAGACAGCAGCAGCCCGGGAGCCTGAGCTCAGGAGGAACTCTTACCTGGAAATTGGGAACT
GTATGGAGACTCCAAACTGACTTCTTTCAAAAAACAAAAACAAAAAATTTTTTTAGCTTTGACAAACACACAAAAGTGGTAATAAAGAGA
GCCCTCCTTGTCAACCCAAAATGTGAGCCCCCTGTGGCAAAACCACCCCCTACCCCATTAACAAATCAACAGACAAAATTCTCCGAGTCC
TTTGCCTCTTTTGATAACATGTTGTTCTGTTTTGTAAAGTGTGTGTGCTTGGGGTTCCGAGGTGTGGGATTGAGTTCTCTGCTTTGTTTT
TTTTTAAGATATTGTATGTAAATGTAAAAAGTTATTTAAATATATATTTTAAAGAACCCTAACTGCCAACTTTTGCTGAAAAAGAAAAAA
AAATCACTGCTGCATTAAATGAACCACATCATGTGTAGATACTGTTGTCTCCCTGAAGGGAGCTCAGGCCTTTGAAAAGCTCAGGGCTTC
ACCTGCCTTAGAAAATGAACCAGAAACTTGAAGTAAAGCTAGTTGATAGGGGTACAGGCTCTGAGGAGCAGTGCAAAACTGCCTCTTTCT
TTCTCGTGGCAAATCCCAATGTACACGATTTCAGGTCTCAGACGCCATGCCTCTCCAGCCCACGCCTTTAGGCAGGTGATGGCAGCAGCT
AGGAATAGGGTGTACATGATCCACAGCCCTGCGGAGCCAGGTCAAGCCGCTGCTATGAAAGCTCCAGGGTGATGGGGACGATTCTGCCCA
GTGTCCTCAGTCTGTCCCCTCAGGTCATGGTCCCAAGTGAAATGACAGAGTTCACAGCCCTGGTCTTGGCTGAGGTCCAGGTCATAGTAA
GGGCATGTTCTTGGGGCCCTCGACCTGAACTCTGACCCTCCGGGCAGGGAAGAGGAGGTTGTCCCCTTTGGTTGTCCTGGCTTTGGAGTC
CTTTGCAAAAATATTTTGGGCCCCCTGCCACTGGCTGCAGAAATGGCTCGACGGGGTGTGTGGGGACAGACACCCAGAAGGAATGTACTT
TTGTGGCCTTGGTGTCCGATGGGGCTGGGGGAGAGTGCTCTCCACTGACCCAGCAGCACACCCATGTGCAGTGCGCCTGCATCTGTGTGG
GGGCAGCCACACCCCTTGGCTGCTGCTTCCTTGGGCTGCCTTTCTGGGGGCATGTGACTGGACCTACGAGGTCTGCACTGAGCTCCATTT
GAATGATACCTTTCCTATCCCATTTCCCCCACGGAAGCACCGCTTCAGGGTTATTCAGTCCTCTGCCTCATGGCTGAAATTGCTCATCTC
GTCTGCAGATGTCTACTATCCTGTCTACCTAATGCACTATTATGTATTGATTCTCCATGAGACAGAGAGAGAGAGAGACTATCAGATAGT
TTACACCCAAAGGGTAGGTTTTTGTATATTTTTCCAGCCTTTTTTATTAAGGGGAAGGGGAGAGTTTAAAAACCCAAACCGTTGTGGTTT
TAAGGTGTTTCATTTTTAAAAGGGAGAGAGAATCTATTTAAAGCTATTTCAGATCAGGGATTGTCATCCTTTTTTGTCCAATGTATTCCT
TGTTCTTTAAAAAAATTTTTTTTAGAGGAAACTAATATTAGTCTTTGTGTTCACTAACTCTTCTGGTCACTTGTATTTATTTATTCATTC
ATTCATCAGATATTTGTTGCCATCTGAAAGAACTGGCCCAGTGGGTCTGAAAGCTCGCTTGAGAATAGGAAACTTGAGACCTGGCCCCCT
GTGGGTAGGAGAACAAGGACCACCTGGGTTCTCCAGTCTTGAACGAGAATCTCACTCTTATCAGAATGTTTTTCTTAACCTCAGCGTATG
ATGAGGAAATTTACTTATCTCTAGCTAGGATTTGACAAATTCCAACATCAAATGATCAAAACATTTGCCACTGAGGCTTCACTGGTGAGA
TCCGTTCTCCGTCCTCGGGTGCAGTCCCTTGGGGGCTGCTCCTCGGACTGCGCCCCGCACACCTGTTATCGAGGGTGTGAGAAGCGCCTA
AGCTGGTGACATGTGATCTGGGACGCCTTCATTTCTCGGGCCAGGAGTAGCAGCTGCTAAGGACAGCAGCTTGCATTGCGTGGTTTTAGG
GAAGCAGGGTCTGGCTTTTAATATGAACTGCAAAAAGCAGCTTCTCACTGATATTTTTTTGTTGTTGTTTCTGGGGGGTTTTTTTGTTTT
GTTTTTAATGCCTTTGAGTGCATATTTTCTTCCTCGTCTGAAACCGAACTCCCAAAGTGGCTTTCTTTAGCCCTGGCTGGAAAACCACCT
CTCAATAGCCTTAAGCAATAAATAGATGAGTAGAGAATGTGGCTTCAACTGGGCTTATTAAAGTAAGTGTGTCTAGTTTTCACTTGAACA
AGTGATAGCTGCAGATGGCGAAAGAAACCCATTTAATTTTTGTAGCTTACAGGTGGTAGAAACAAAAATGCAATTTTAAAACCTTAAATA
CCAAATACCAACCATTGCCTTTTTTTTTTTTGAGATGGAATTTTGCTCTTGTCACCCAGGCTGGAGTGCAATGGCGCGATCTCACCTCAC
TGCAACCTCTGCCTCCCGGGTCCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCGCCACCACACCCAGCTA
ATTTTGTATTTTTGGTAGAGACAGGGTATCTCCATGTTGGTCAGGCTGGTCTTGGATTCCCGACCTCAGGTGATCCGCCCACCTCGGCCT
CCCAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCTGCCCAGCAATACCAACCATTGTCTTTTAAATTCGTGTTGGCTTCTCAGACA
GGGAGATCACTGGAATAAAATAACCGATGGTCTTATTTTGTCACACGTAAATCAAAAGAAATGTCCTCTTTGAAGTTGTAAGACTCCACC
AATGACAGACACCCTTTTCGGTGGACTCTGAGTGGTGTGTAGTGGTTTTATAGCCATGGAAACTAGGAGTATCTCACTTTCCACTGAGAA
CCCCTGCCCCCAATCCCTCTAAGTTGGGGTGTGGCAGTTGGGCAGGGTCAAGTGACCCAGCCCTGGCTGTAGGACAGCCATATACAGTGA
AGAGTTCTAGAACCAGCTAAAAATGGAAGTTTGGGTGTTTACCAACAAGGTACCTCTTTATGGATGCAGCCCCAGTAAGCTGGCTTTAAC
TCTCAGCTCCTTCCCTGTCTCCTCCTAATCCAAGCCCTTTTATAAAATAAAGCCCCTTCTGTCCCACTGCTCACATACTTATGTGCTGCT
AGTCTCTACTCGAAGTTCGTGCAGGACTAATGCTTTTAAAATGAGGTCTAAAAAATAATTACTAGTCGAGACTATTATTCTTTAAACAGA
ACTGCCTTTTTCTACTCTTTATGTAAACTCTTTCTATTGTGTTGGTCTAACAAGGCACTATTTTAAAATTTTTTAATTTTTCCCATAGCA
CTTAAAAGAGATTTTGTAAAGACCTTGCTGTAAAGATTTTGTAATAAAATGGTCTAAGGGCTCTTTTTCCAACATTACCATTTTTAAAAA
ATGTTTTAAAAGCTAGAAGACAACTTATGTATATTCTGTATATGTATAGCAGCACATTTCATTTATGGAAATATGTTCTCAGAATATTTA
TTTACTAATATATTTATCTTAAGCCATGTCTTATGTTGAGAGTGTGACATTGTTGGAATAATCATTGAAAATGACTAACACAAGACCCTG
TAAATACATGATAATTGCACACAGATTTTACATATTTGCAGACCAAAAATGATTTAAAACAAGTTGTAGTCTTCTATGGTTTTGTAACAA

>27381_27381_5_ERG-ZNRF3_ERG_chr21_39947586_ENST00000398919_ZNRF3_chr22_29383064_ENST00000332811_length(amino acids)=852AA_BP=16
MKDMIQTVPDPAAHIKMHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSED
PLKRPVVYVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQALEKMET
RKFNSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVETSNL
SRGRQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLYSPQTPAYIRSYPPLHLDHSLAAHRCGLEHRAYSPAH
PFRRPKLSGRSFSKAACFSQYETMYQHYYFQGLSYPEQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSFSCYHG
HRSVCSGYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDYDPFIYRSRSPCRASEAGGSGSSGRGPALCF
EGSPPPEELPAVHSHGAGRGEPWPGPASPSGDQVSTCSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPSCACCC
EPQPSPAGPSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPCCFYEEKQVARGGGGGSGCYTEDYSV
SVQYTLTEEPPPGCYPGARDLSQRIPIIPEDVDCDLGLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLRPGCPP

--------------------------------------------------------------
>27381_27381_6_ERG-ZNRF3_ERG_chr21_39947586_ENST00000398919_ZNRF3_chr22_29383064_ENST00000402174_length(transcript)=2908nt_BP=334nt
GCTGAGCCCGTCGGCGCCGAGGGAGTTAGTGCGACCCGGCTCGGCGCGCACGGCCAAGGCACGCGCGCTGGCACACGCGGGCGCGGACAC
GCGCGGACACACACGTGCGGGACACGCCCTCCCCCGACGGCGGCGCTAACCTCTCGGTTATTCCAGGATCTTTGGAGACCCGAGGAAAGC
CGTGTTGACCAAAAGCAAGACAAATGACTCACAGAGAAAAAAGATGGCAGAACCAAGGGCAACTAAAGCCGTCAGGTTCTGAACAGCTGG
TAGATGGGCTGGCTTACTGAAGGACATGATTCAGACTGTCCCGGACCCAGCAGCTCATATCAAGATGCACCCACTGGGCCTATGTAATAA
CAATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAACAGCCAGAATTGGACCCGAAACCATGCCTCACTGT
CCTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATGTGTCTGAAAACCCAGAAGCTATTGATCAGCTGAA
CCAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATGCCATTAAGCTGATGAACATCGTCAACAAGCAGAA
AGTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTGACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGT
CTCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTCAGAATTCCATGAACAGGCTGGCTGTGCAGGCTCT
AGAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGAGCTGTGGGGCCCTGGACACACTCAGCAGCAGCTC
CACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGGTCATCCCCTGTACTCACCGGTTTCACAGGAAGTG
CGTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCATAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGT
GGAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATTACCCCGGCCGCGTGCACAGGACCAACGCCATCCC
AGCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGACCATGGACCGGCACGGGGAGCAGAGCCTCTATTC
CCCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCCTGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGC
CTACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAAGGCAGCTTGCTTCTCCCAGTATGAGACCATGTA
CCAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCACCTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTT
TCCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGCCCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTT
CAGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAGGCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCA
GTGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGGGCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTC
CCTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCAGTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGG
ACCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACAGTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGG
CCCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACAGCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAA
TAGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCAGGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTC
GTGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGCTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCT
CTACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTTGTACGGCCTTCACCCCGACCATTTGCCCAGGAC
AGATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGGCCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACAC
TGAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCTGCTACCCCGGGGCCCGGGACCTGAGCCAGCGCAT
CCCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAGGGACCCACAGCCTCGGCTCCTGGGGTGGGACGCG
AGGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGCGGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCG
GCCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCCTCCAGGACACTCAGGAGTCCAGCACCACTGCCAC
TGAGGCTGCAGGACCGAGATCTCACTCAGCAGACAGCAGCAGCCCGGGAGCCTGAGCTCAGGAGGAACTCTTACCTGGAAATTGGGAACT

>27381_27381_6_ERG-ZNRF3_ERG_chr21_39947586_ENST00000398919_ZNRF3_chr22_29383064_ENST00000402174_length(amino acids)=852AA_BP=16
MKDMIQTVPDPAAHIKMHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSED
PLKRPVVYVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQALEKMET
RKFNSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVETSNL
SRGRQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLYSPQTPAYIRSYPPLHLDHSLAAHRCGLEHRAYSPAH
PFRRPKLSGRSFSKAACFSQYETMYQHYYFQGLSYPEQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSFSCYHG
HRSVCSGYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDYDPFIYRSRSPCRASEAGGSGSSGRGPALCF
EGSPPPEELPAVHSHGAGRGEPWPGPASPSGDQVSTCSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPSCACCC
EPQPSPAGPSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPCCFYEEKQVARGGGGGSGCYTEDYSV
SVQYTLTEEPPPGCYPGARDLSQRIPIIPEDVDCDLGLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLRPGCPP

--------------------------------------------------------------
>27381_27381_7_ERG-ZNRF3_ERG_chr21_39947586_ENST00000398919_ZNRF3_chr22_29383064_ENST00000406323_length(transcript)=3187nt_BP=334nt
GCTGAGCCCGTCGGCGCCGAGGGAGTTAGTGCGACCCGGCTCGGCGCGCACGGCCAAGGCACGCGCGCTGGCACACGCGGGCGCGGACAC
GCGCGGACACACACGTGCGGGACACGCCCTCCCCCGACGGCGGCGCTAACCTCTCGGTTATTCCAGGATCTTTGGAGACCCGAGGAAAGC
CGTGTTGACCAAAAGCAAGACAAATGACTCACAGAGAAAAAAGATGGCAGAACCAAGGGCAACTAAAGCCGTCAGGTTCTGAACAGCTGG
TAGATGGGCTGGCTTACTGAAGGACATGATTCAGACTGTCCCGGACCCAGCAGCTCATATCAAGTGCACCCACTGGGCCTATGTAATAAC
AATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAACAGCCAGAATTGGACCCGAAACCATGCCTCACTGTC
CTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATGTGTCTGAAAACCCAGAAGCTATTGATCAGCTGAAC
CAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATGCCATTAAGCTGATGAACATCGTCAACAAGCAGAAA
GTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTGACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTC
TCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTCAGAATTCCATGAACAGGCTGGCTGTGCAGGCTCTA
GAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGAGCTGTGGGGCCCTGGACACACTCAGCAGCAGCTCC
ACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGGTCATCCCCTGTACTCACCGGTTTCACAGGAAGTGC
GTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCATAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTG
GAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATTACCCCGGCCGCGTGCACAGGACCAACGCCATCCCA
GCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGACCATGGACCGGCACGGGGAGCAGAGCCTCTATTCC
CCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCCTGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCC
TACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAAGGCAGCTTGCTTCTCCCAGTATGAGACCATGTAC
CAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCACCTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTT
CCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGCCCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTC
AGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAGGCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAG
TGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGGGCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCC
CTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCAGTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGA
CCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACAGTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGC
CCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACAGCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAAT
AGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCAGGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCG
TGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGCTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTC
TACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTTGTACGGCCTTCACCCCGACCATTTGCCCAGGACA
GATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGGCCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACT
GAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCTGCTACCCCGGGGCCCGGGACCTGAGCCAGCGCATC
CCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAGGGACCCACAGCCTCGGCTCCTGGGGTGGGACGCGA
GGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGCGGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGG
CCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCCTCCAGGACACTCAGGAGTCCAGCACCACTGCCACT
GAGGCTGCAGGACCGAGATCTCACTCAGCAGACAGCAGCAGCCCGGGAGCCTGAGCTCAGGAGGAACTCTTACCTGGAAATTGGGAACTG
TATGGAGACTCCAAACTGACTTCTTTCAAAAAACAAAAACAAAAAATTTTTTTAGCTTTGACAAACACACAAAAGTGGTAATAAAGAGAG
CCCTCCTTGTCAACCCAAAATGTGAGCCCCCTGTGGCAAAACCACCCCCTACCCCATTAACAAATCAACAGACAAAATTCTCCGAGTCCT
TTGCCTCTTTTGATAACATGTTGTTCTGTTTTGTAAAGTGTGTGTGCTTGGGGTTCCGAGGTGTGGGATTGAGTTCTCTGCTTTGTTTTT

>27381_27381_7_ERG-ZNRF3_ERG_chr21_39947586_ENST00000398919_ZNRF3_chr22_29383064_ENST00000406323_length(amino acids)=856AA_BP=21
MGWLTEGHDSDCPGPSSSYQVHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQ
GSEDPLKRPVVYVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQALE
KMETRKFNSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVE
TSNLSRGRQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLYSPQTPAYIRSYPPLHLDHSLAAHRCGLEHRAY
SPAHPFRRPKLSGRSFSKAACFSQYETMYQHYYFQGLSYPEQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSFS
CYHGHRSVCSGYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDYDPFIYRSRSPCRASEAGGSGSSGRGP
ALCFEGSPPPEELPAVHSHGAGRGEPWPGPASPSGDQVSTCSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPSC
ACCCEPQPSPAGPSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPCCFYEEKQVARGGGGGSGCYTE
DYSVSVQYTLTEEPPPGCYPGARDLSQRIPIIPEDVDCDLGLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLRP

--------------------------------------------------------------
>27381_27381_8_ERG-ZNRF3_ERG_chr21_39947586_ENST00000398919_ZNRF3_chr22_29383064_ENST00000544604_length(transcript)=6710nt_BP=334nt
GCTGAGCCCGTCGGCGCCGAGGGAGTTAGTGCGACCCGGCTCGGCGCGCACGGCCAAGGCACGCGCGCTGGCACACGCGGGCGCGGACAC
GCGCGGACACACACGTGCGGGACACGCCCTCCCCCGACGGCGGCGCTAACCTCTCGGTTATTCCAGGATCTTTGGAGACCCGAGGAAAGC
CGTGTTGACCAAAAGCAAGACAAATGACTCACAGAGAAAAAAGATGGCAGAACCAAGGGCAACTAAAGCCGTCAGGTTCTGAACAGCTGG
TAGATGGGCTGGCTTACTGAAGGACATGATTCAGACTGTCCCGGACCCAGCAGCTCATATCAAGATGCACCCACTGGGCCTATGTAATAA
CAATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAACAGCCAGAATTGGACCCGAAACCATGCCTCACTGT
CCTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATGTGTCTGAAAACCCAGAAGCTATTGATCAGCTGAA
CCAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATGCCATTAAGCTGATGAACATCGTCAACAAGCAGAA
AGTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTGACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGT
CTCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTCAGAATTCCATGAACAGGCTGGCTGTGCAGGCTCT
AGAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGAGCTGTGGGGCCCTGGACACACTCAGCAGCAGCTC
CACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGGTCATCCCCTGTACTCACCGGTTTCACAGGAAGTG
CGTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCATAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGT
GGAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATTACCCCGGCCGCGTGCACAGGACCAACGCCATCCC
AGCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGACCATGGACCGGCACGGGGAGCAGAGCCTCTATTC
CCCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCCTGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGC
CTACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAAGGCAGCTTGCTTCTCCCAGTATGAGACCATGTA
CCAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCACCTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTT
TCCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGCCCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTT
CAGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAGGCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCA
GTGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGGGCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTC
CCTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCAGTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGG
ACCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACAGTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGG
CCCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACAGCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAA
TAGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCAGGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTC
GTGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGCTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCT
CTACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTTGTACGGCCTTCACCCCGACCATTTGCCCAGGAC
AGATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGGCCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACAC
TGAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCTGCTACCCCGGGGCCCGGGACCTGAGCCAGCGCAT
CCCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAGGGACCCACAGCCTCGGCTCCTGGGGTGGGACGCG
AGGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGCGGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCG
GCCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCCTCCAGGACACTCAGGAGTCCAGCACCACTGCCAC
TGAGGCTGCAGGACCGAGATCTCACTCAGCAGACAGCAGCAGCCCGGGAGCCTGAGCTCAGGAGGAACTCTTACCTGGAAATTGGGAACT
GTATGGAGACTCCAAACTGACTTCTTTCAAAAAACAAAAACAAAAAATTTTTTTAGCTTTGACAAACACACAAAAGTGGTAATAAAGAGA
GCCCTCCTTGTCAACCCAAAATGTGAGCCCCCTGTGGCAAAACCACCCCCTACCCCATTAACAAATCAACAGACAAAATTCTCCGAGTCC
TTTGCCTCTTTTGATAACATGTTGTTCTGTTTTGTAAAGTGTGTGTGCTTGGGGTTCCGAGGTGTGGGATTGAGTTCTCTGCTTTGTTTT
TTTTTAAGATATTGTATGTAAATGTAAAAAGTTATTTAAATATATATTTTAAAGAACCCTAACTGCCAACTTTTGCTGAAAAAGAAAAAA
AAATCACTGCTGCATTAAATGAACCACATCATGTGTAGATACTGTTGTCTCCCTGAAGGGAGCTCAGGCCTTTGAAAAGCTCAGGGCTTC
ACCTGCCTTAGAAAATGAACCAGAAACTTGAAGTAAAGCTAGTTGATAGGGGTACAGGCTCTGAGGAGCAGTGCAAAACTGCCTCTTTCT
TTCTCGTGGCAAATCCCAATGTACACGATTTCAGGTCTCAGACGCCATGCCTCTCCAGCCCACGCCTTTAGGCAGGTGATGGCAGCAGCT
AGGAATAGGGTGTACATGATCCACAGCCCTGCGGAGCCAGGTCAAGCCGCTGCTATGAAAGCTCCAGGGTGATGGGGACGATTCTGCCCA
GTGTCCTCAGTCTGTCCCCTCAGGTCATGGTCCCAAGTGAAATGACAGAGTTCACAGCCCTGGTCTTGGCTGAGGTCCAGGTCATAGTAA
GGGCATGTTCTTGGGGCCCTCGACCTGAACTCTGACCCTCCGGGCAGGGAAGAGGAGGTTGTCCCCTTTGGTTGTCCTGGCTTTGGAGTC
CTTTGCAAAAATATTTTGGGCCCCCTGCCACTGGCTGCAGAAATGGCTCGACGGGGTGTGTGGGGACAGACACCCAGAAGGAATGTACTT
TTGTGGCCTTGGTGTCCGATGGGGCTGGGGGAGAGTGCTCTCCACTGACCCAGCAGCACACCCATGTGCAGTGCGCCTGCATCTGTGTGG
GGGCAGCCACACCCCTTGGCTGCTGCTTCCTTGGGCTGCCTTTCTGGGGGCATGTGACTGGACCTACGAGGTCTGCACTGAGCTCCATTT
GAATGATACCTTTCCTATCCCATTTCCCCCACGGAAGCACCGCTTCAGGGTTATTCAGTCCTCTGCCTCATGGCTGAAATTGCTCATCTC
GTCTGCAGATGTCTACTATCCTGTCTACCTAATGCACTATTATGTATTGATTCTCCATGAGACAGAGAGAGAGAGAGACTATCAGATAGT
TTACACCCAAAGGGTAGGTTTTTGTATATTTTTCCAGCCTTTTTTATTAAGGGGAAGGGGAGAGTTTAAAAACCCAAACCGTTGTGGTTT
TAAGGTGTTTCATTTTTAAAAGGGAGAGAGAATCTATTTAAAGCTATTTCAGATCAGGGATTGTCATCCTTTTTTGTCCAATGTATTCCT
TGTTCTTTAAAAAAATTTTTTTTAGAGGAAACTAATATTAGTCTTTGTGTTCACTAACTCTTCTGGTCACTTGTATTTATTTATTCATTC
ATTCATCAGATATTTGTTGCCATCTGAAAGAACTGGCCCAGTGGGTCTGAAAGCTCGCTTGAGAATAGGAAACTTGAGACCTGGCCCCCT
GTGGGTAGGAGAACAAGGACCACCTGGGTTCTCCAGTCTTGAACGAGAATCTCACTCTTATCAGAATGTTTTTCTTAACCTCAGCGTATG
ATGAGGAAATTTACTTATCTCTAGCTAGGATTTGACAAATTCCAACATCAAATGATCAAAACATTTGCCACTGAGGCTTCACTGGTGAGA
TCCGTTCTCCGTCCTCGGGTGCAGTCCCTTGGGGGCTGCTCCTCGGACTGCGCCCCGCACACCTGTTATCGAGGGTGTGAGAAGCGCCTA
AGCTGGTGACATGTGATCTGGGACGCCTTCATTTCTCGGGCCAGGAGTAGCAGCTGCTAAGGACAGCAGCTTGCATTGCGTGGTTTTAGG
GAAGCAGGGTCTGGCTTTTAATATGAACTGCAAAAAGCAGCTTCTCACTGATATTTTTTTGTTGTTGTTTCTGGGGGGTTTTTTTGTTTT
GTTTTTAATGCCTTTGAGTGCATATTTTCTTCCTCGTCTGAAACCGAACTCCCAAAGTGGCTTTCTTTAGCCCTGGCTGGAAAACCACCT
CTCAATAGCCTTAAGCAATAAATAGATGAGTAGAGAATGTGGCTTCAACTGGGCTTATTAAAGTAAGTGTGTCTAGTTTTCACTTGAACA
AGTGATAGCTGCAGATGGCGAAAGAAACCCATTTAATTTTTGTAGCTTACAGGTGGTAGAAACAAAAATGCAATTTTAAAACCTTAAATA
CCAAATACCAACCATTGCCTTTTTTTTTTTTGAGATGGAATTTTGCTCTTGTCACCCAGGCTGGAGTGCAATGGCGCGATCTCACCTCAC
TGCAACCTCTGCCTCCCGGGTCCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCGCCACCACACCCAGCTA
ATTTTGTATTTTTGGTAGAGACAGGGTATCTCCATGTTGGTCAGGCTGGTCTTGGATTCCCGACCTCAGGTGATCCGCCCACCTCGGCCT
CCCAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCTGCCCAGCAATACCAACCATTGTCTTTTAAATTCGTGTTGGCTTCTCAGACA
GGGAGATCACTGGAATAAAATAACCGATGGTCTTATTTTGTCACACGTAAATCAAAAGAAATGTCCTCTTTGAAGTTGTAAGACTCCACC
AATGACAGACACCCTTTTCGGTGGACTCTGAGTGGTGTGTAGTGGTTTTATAGCCATGGAAACTAGGAGTATCTCACTTTCCACTGAGAA
CCCCTGCCCCCAATCCCTCTAAGTTGGGGTGTGGCAGTTGGGCAGGGTCAAGTGACCCAGCCCTGGCTGTAGGACAGCCATATACAGTGA
AGAGTTCTAGAACCAGCTAAAAATGGAAGTTTGGGTGTTTACCAACAAGGTACCTCTTTATGGATGCAGCCCCAGTAAGCTGGCTTTAAC
TCTCAGCTCCTTCCCTGTCTCCTCCTAATCCAAGCCCTTTTATAAAATAAAGCCCCTTCTGTCCCACTGCTCACATACTTATGTGCTGCT
AGTCTCTACTCGAAGTTCGTGCAGGACTAATGCTTTTAAAATGAGGTCTAAAAAATAATTACTAGTCGAGACTATTATTCTTTAAACAGA
ACTGCCTTTTTCTACTCTTTATGTAAACTCTTTCTATTGTGTTGGTCTAACAAGGCACTATTTTAAAATTTTTTAATTTTTCCCATAGCA
CTTAAAAGAGATTTTGTAAAGACCTTGCTGTAAAGATTTTGTAATAAAATGGTCTAAGGGCTCTTTTTCCAACATTACCATTTTTAAAAA
ATGTTTTAAAAGCTAGAAGACAACTTATGTATATTCTGTATATGTATAGCAGCACATTTCATTTATGGAAATATGTTCTCAGAATATTTA
TTTACTAATATATTTATCTTAAGCCATGTCTTATGTTGAGAGTGTGACATTGTTGGAATAATCATTGAAAATGACTAACACAAGACCCTG
TAAATACATGATAATTGCACACAGATTTTACATATTTGCAGACCAAAAATGATTTAAAACAAGTTGTAGTCTTCTATGGTTTTGTAACAA

>27381_27381_8_ERG-ZNRF3_ERG_chr21_39947586_ENST00000398919_ZNRF3_chr22_29383064_ENST00000544604_length(amino acids)=852AA_BP=16
MKDMIQTVPDPAAHIKMHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSED
PLKRPVVYVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQALEKMET
RKFNSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVETSNL
SRGRQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLYSPQTPAYIRSYPPLHLDHSLAAHRCGLEHRAYSPAH
PFRRPKLSGRSFSKAACFSQYETMYQHYYFQGLSYPEQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSFSCYHG
HRSVCSGYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDYDPFIYRSRSPCRASEAGGSGSSGRGPALCF
EGSPPPEELPAVHSHGAGRGEPWPGPASPSGDQVSTCSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPSCACCC
EPQPSPAGPSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPCCFYEEKQVARGGGGGSGCYTEDYSV
SVQYTLTEEPPPGCYPGARDLSQRIPIIPEDVDCDLGLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLRPGCPP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ERG-ZNRF3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ERG-ZNRF3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ERG-ZNRF3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneERGC0033578Prostatic Neoplasms7CTD_human
HgeneERGC0376358Malignant neoplasm of prostate7CTD_human
HgeneERGC0023418leukemia1CTD_human
HgeneERGC0023452Childhood Acute Lymphoblastic Leukemia1CTD_human
HgeneERGC0023453L2 Acute Lymphoblastic Leukemia1CTD_human
HgeneERGC0023467Leukemia, Myelocytic, Acute1CTD_human
HgeneERGC0026998Acute Myeloid Leukemia, M11CTD_human
HgeneERGC0279980Extra-osseous Ewing's sarcoma1ORPHANET
HgeneERGC1879321Acute Myeloid Leukemia (AML-M2)1CTD_human
HgeneERGC1961102Precursor Cell Lymphoblastic Leukemia Lymphoma1CTD_human
TgeneC0030297Pancreatic Neoplasm2CTD_human
TgeneC0346647Malignant neoplasm of pancreas2CTD_human
TgeneC0206686Adrenocortical carcinoma1CTD_human