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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
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Fusion gene:ESRRG-ACBD3 (FusionGDB2 ID:HG2104TG64746)

Fusion Gene Summary for ESRRG-ACBD3

Fusion gene summary

Fusion gene information	Fusion gene name: ESRRG-ACBD3
	Fusion gene ID: hg2104tg64746
		Hgene	Tgene
	Gene symbol	ESRRG	ACBD3
	Gene ID	2104	64746
	Gene name	estrogen related receptor gamma	acyl-CoA binding domain containing 3
	Synonyms	ERR-gamma\|ERR3\|ERRg\|ERRgamma\|NR3B3	GCP60\|GOCAP1\|GOLPH1\|PAP7
	Cytomap	('ESRRG')('ACBD3') 1q41	1q42.12
	Type of gene	protein-coding	protein-coding
	Description	estrogen-related receptor gammaERR gamma-2estrogen receptor-related protein 3nuclear receptor subfamily 3 group B member 3	Golgi resident protein GCP60PBR- and PKA-associated protein 7PKA (RIalpha)-associated proteinacyl-Coenzyme A binding domain containing 3golgi complex associated protein 1, 60kDagolgi phosphoprotein 1peripheral benzodiazepine receptor-associated prot
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000359162, ENST00000360012, ENST00000361395, ENST00000361525, ENST00000366937, ENST00000366938, ENST00000366940, ENST00000391890, ENST00000408911, ENST00000463665, ENST00000487276, ENST00000493603, ENST00000493748, ENST00000471371,
Fusion gene scores	* DoF score	6 X 6 X 2=72	8 X 7 X 5=280
	# samples	6	8
	** MAII score	log2(6/72*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(8/280*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: ESRRG [Title/Abstract] AND ACBD3 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ESRRG(216850418)-ACBD3(226353701), # samples:1
Anticipated loss of major functional domain due to fusion event.	ESRRG-ACBD3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ESRRG-ACBD3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ESRRG-ACBD3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ESRRG-ACBD3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ESRRG-ACBD3 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. ESRRG-ACBD3 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF. ESRRG-ACBD3 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	ESRRG	GO:0006355	regulation of transcription, DNA-templated	23836911

Fusion gene breakpoints across ESRRG (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across ACBD3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-B6-A0IQ-01A	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-

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Fusion Gene ORF analysis for ESRRG-ACBD3

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000359162	ENST00000464927	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
5CDS-intron	ENST00000360012	ENST00000464927	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
5CDS-intron	ENST00000361395	ENST00000464927	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
5CDS-intron	ENST00000361525	ENST00000464927	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
5CDS-intron	ENST00000366937	ENST00000464927	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
5CDS-intron	ENST00000366938	ENST00000464927	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
5CDS-intron	ENST00000366940	ENST00000464927	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
5CDS-intron	ENST00000391890	ENST00000464927	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
5CDS-intron	ENST00000408911	ENST00000464927	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
5CDS-intron	ENST00000463665	ENST00000464927	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
5CDS-intron	ENST00000487276	ENST00000464927	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
5CDS-intron	ENST00000493603	ENST00000464927	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
5CDS-intron	ENST00000493748	ENST00000464927	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
Frame-shift	ENST00000359162	ENST00000366812	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
Frame-shift	ENST00000360012	ENST00000366812	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
Frame-shift	ENST00000361525	ENST00000366812	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
Frame-shift	ENST00000366937	ENST00000366812	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
Frame-shift	ENST00000366938	ENST00000366812	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
Frame-shift	ENST00000366940	ENST00000366812	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
Frame-shift	ENST00000391890	ENST00000366812	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
Frame-shift	ENST00000463665	ENST00000366812	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
Frame-shift	ENST00000487276	ENST00000366812	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
Frame-shift	ENST00000493603	ENST00000366812	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
In-frame	ENST00000361395	ENST00000366812	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
In-frame	ENST00000408911	ENST00000366812	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
In-frame	ENST00000493748	ENST00000366812	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
intron-3CDS	ENST00000471371	ENST00000366812	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-
intron-intron	ENST00000471371	ENST00000464927	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000361395	ESRRG	chr1	216850418	-	ENST00000366812	ACBD3	chr1	226353701	-	3858	626	193	1926	577
ENST00000493748	ESRRG	chr1	216850418	-	ENST00000366812	ACBD3	chr1	226353701	-	4250	1018	585	2318	577
ENST00000408911	ESRRG	chr1	216850418	-	ENST00000366812	ACBD3	chr1	226353701	-	3858	626	121	1926	601

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000361395	ENST00000366812	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-	0.000273528	0.9997265
ENST00000493748	ENST00000366812	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-	0.000282836	0.9997172
ENST00000408911	ENST00000366812	ESRRG	chr1	216850418	-	ACBD3	chr1	226353701	-	0.000219457	0.9997806

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Fusion Genomic Features for ESRRG-ACBD3

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

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Fusion Protein Features for ESRRG-ACBD3

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:216850418/chr1:226353701)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000366937

128_148

162

471.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000408911

128_148

157

459.0

Zinc finger

NR C4-type

Tgene

ACBD3

chr1:216850418

chr1:226353701

ENST00000366812

174_257

529.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ACBD3

chr1:216850418

chr1:226353701

ENST00000366812

182_240

529.0

Compositional bias

Note=Glu-rich

Tgene

ACBD3

chr1:216850418

chr1:226353701

ENST00000366812

196_238

529.0

Compositional bias

Note=Arg-rich

Tgene

ACBD3

chr1:216850418

chr1:226353701

ENST00000366812

384_526

529.0

Domain

GOLD

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000359162

125_200

134

436.0

DNA binding

Nuclear receptor

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000360012

125_200

134

436.0

DNA binding

Nuclear receptor

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000361395

125_200

134

436.0

DNA binding

Nuclear receptor

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000361525

125_200

134

436.0

DNA binding

Nuclear receptor

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000366937

125_200

162

471.0

DNA binding

Nuclear receptor

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000366938

125_200

134

436.0

DNA binding

Nuclear receptor

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000366940

125_200

134

436.0

DNA binding

Nuclear receptor

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000391890

125_200

134

443.0

DNA binding

Nuclear receptor

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000408911

125_200

157

459.0

DNA binding

Nuclear receptor

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000463665

125_200

134

397.0

DNA binding

Nuclear receptor

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000487276

125_200

134

436.0

DNA binding

Nuclear receptor

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000493603

125_200

134

436.0

DNA binding

Nuclear receptor

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000493748

125_200

134

436.0

DNA binding

Nuclear receptor

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000359162

233_457

134

436.0

Domain

NR LBD

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000360012

233_457

134

436.0

Domain

NR LBD

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000361395

233_457

134

436.0

Domain

NR LBD

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000361525

233_457

134

436.0

Domain

NR LBD

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000366937

233_457

162

471.0

Domain

NR LBD

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000366938

233_457

134

436.0

Domain

NR LBD

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000366940

233_457

134

436.0

Domain

NR LBD

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000391890

233_457

134

443.0

Domain

NR LBD

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000408911

233_457

157

459.0

Domain

NR LBD

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000463665

233_457

134

397.0

Domain

NR LBD

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000487276

233_457

134

436.0

Domain

NR LBD

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000493603

233_457

134

436.0

Domain

NR LBD

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000493748

233_457

134

436.0

Domain

NR LBD

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000359162

128_148

134

436.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000359162

164_188

134

436.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000360012

128_148

134

436.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000360012

164_188

134

436.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000361395

128_148

134

436.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000361395

164_188

134

436.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000361525

128_148

134

436.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000361525

164_188

134

436.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000366937

164_188

162

471.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000366938

128_148

134

436.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000366938

164_188

134

436.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000366940

128_148

134

436.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000366940

164_188

134

436.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000391890

128_148

134

443.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000391890

164_188

134

443.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000408911

164_188

157

459.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000463665

128_148

134

397.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000463665

164_188

134

397.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000487276

128_148

134

436.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000487276

164_188

134

436.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000493603

128_148

134

436.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000493603

164_188

134

436.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000493748

128_148

134

436.0

Zinc finger

NR C4-type

Hgene

ESRRG

chr1:216850418

chr1:226353701

ENST00000493748

164_188

134

436.0

Zinc finger

NR C4-type

Tgene

ACBD3

chr1:216850418

chr1:226353701

ENST00000366812

21_60

529.0

Compositional bias

Note=Pro-rich

Tgene

ACBD3

chr1:216850418

chr1:226353701

ENST00000366812

83_174

529.0

Domain

ACB

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Fusion Gene Sequence for ESRRG-ACBD3

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>27588_27588_1_ESRRG-ACBD3_ESRRG_chr1_216850418_ENST00000361395_ACBD3_chr1_226353701_ENST00000366812_length(transcript)=3858nt_BP=626nt
AGCTGACAATTTACTGGTTCATCAATGAAACAATATTAAATTATGAAGATGTAAGGAAAAAATCCTACGCTAACACTGTCGCAGTTTGAA
AGCTTTAAAAAGTTGAAGTCTATTGGAAACCTTCTTATAAGAAACCTTCCTAGTCAGAGAATTCAACTTTCTTCTTTTCTTCATTCATGA
AAATGCAGATCCACTGAGAAAGGGAATAAGGCTTCTCTGCAGAATGTCAAACAAAGATCGACACATTGATTCCAGCTGTTCGTCCTTCAT
CAAGACGGAACCTTCCAGCCCAGCCTCCCTGACGGACAGCGTCAACCACCACAGCCCTGGTGGCTCTTCAGACGCCAGTGGGAGCTACAG
TTCAACCATGAATGGCCATCAGAACGGACTTGACTCGCCACCTCTCTACCCTTCTGCTCCTATCCTGGGAGGTAGTGGGCCTGTCAGGAA
ACTGTATGATGACTGCTCCAGCACCATTGTTGAAGATCCCCAGACCAAGTGTGAATACATGCTCAACTCGATGCCCAAGAGACTGTGTTT
AGTGTGTGGTGACATCGCTTCTGGGTACCACTATGGGGTAGCATCATGTGAAGCCTGCAAGGCATTCTTCAAGAGGACAATTCAAGAAAA
AGATGGCAAAGCATTTCATCCAACTTATGAAGAAAAATTGAAGCTTGTGGCACTGCATAAGCAAGTTCTTATGGGCCCATATAATCCAGA
CACTTGTCCTGAGGTTGGATTCTTTGATGTGTTGGGGAATGACAGGAGGAGAGAATGGGCAGCCCTGGGAAACATGTCTAAAGAGGATGC
CATGGTGGAGTTTGTCAAGCTCTTAAATAGGTGTTGCCATCTCTTTTCAACATATGTTGCGTCCCACAAAATAGAGAAGGAAGAGCAAGA
AAAAAAAAGGAAGGAGGAAGAGGAGCGAAGGCGGCGTGAAGAGGAAGAAAGAGAACGTCTGCAAAAGGAGGAAGAGAAACGTAGGAGAGA
AGAAGAGGAAAGGCTTCGACGGGAGGAAGAGGAAAGGAGACGGATAGAAGAAGAAAGGCTTCGGTTGGAGCAGCAAAAGCAGCAGATAAT
GGCAGCTTTAAACTCCCAGACTGCCGTGCAGTTCCAGCAGTATGCAGCCCAACAGTATCCAGGGAACTACGAACAGCAGCAAATTCTCAT
CCGCCAGTTGCAGGAGCAACACTATCAGCAGTACATGCAGCAGTTGTATCAAGTCCAGCTTGCACAGCAACAGGCAGCATTACAGAAACA
ACAGGAAGTAGTAGTGGCTGGGTCTTCCTTGCCTACATCATCAAAAGTGAATGCAACTGTACCAAGTAATATGATGTCAGTTAATGGACA
GGCCAAAACACACACTGACAGCTCCGAAAAAGAACTGGAACCAGAAGCTGCAGAAGAAGCCCTGGAGAATGGACCAAAAGAATCTCTTCC
AGTAATAGCAGCTCCATCCATGTGGACACGACCTCAGATCAAAGACTTCAAAGAGAAGATTCAGCAGGATGCAGATTCCGTGATTACAGT
GGGCCGAGGAGAAGTGGTCACTGTTCGAGTACCCACCCATGAAGAAGGATCATATCTCTTTTGGGAATTTGCCACAGACAATTATGACAT
TGGGTTTGGGGTGTATTTTGAATGGACAGACTCTCCAAACACTGCTGTCAGCGTGCATGTCAGTGAGTCCAGCGATGACGACGAGGAGGA
AGAAGAAAACATCGGTTGTGAAGAGAAAGCCAAAAAGAATGCCAACAAGCCTTTGCTGGATGAGATTGTGCCTGTGTACCGACGGGACTG
TCATGAGGAGGTGTATGCTGGCAGCCATCAATATCCAGGGAGAGGAGTCTATCTCCTCAAGTTTGACAACTCCTACTCTTTGTGGCGGTC
AAAATCAGTCTACTACAGAGTCTATTATACTAGATAAAAATGTTGTTACAAAGTCTGGAGTCTAGGGTTGGGCAGAAGATGACATTTAAT
TTGGAAATTTCTTTTTACTTTTGTGGAGCATTAGAGTCACAGTTTACCTTATTGATATTGGTCTGATGGTTTGTGAACTCTTGCTGGGAA
TCAAAATTTCCTTGAGACTCTTTAGCATTCATACTTTGGGGTTAAAGGAGATTCCTCAGACTCATCCAGCCCTTGGGTGCTGACCAGCAG
AGTCACTAGTGGATGCTGAAGTTACATGAGCTACATGTTAAATATTTAAAGTCTCCAAAATAAAACACCCCAACGTTGACCTTACCCGGC
TGATGGTTAGCCCCTTGCTGCCTGCTCCATGTGTCTTATGAGAGCCCGTAGTTACAGTGTCCTCTAATTTGAAATCCATAAGTTAACAAG
TCTATATCAGGTGCAGCTGGCTTTGATTAAAGGCCATTTTTAAAACTTAAAAACTCAACACCTCACAGATTATAATAGAAAAAGAAATGG
CCTCAGTTTGATCTCGTTCAGAATGACCCAGATTGTTTCTGCTTTGGGTGCAGCTGTTTAGTTCAGAGTTATATTACAGAGAATTATTTT
CTGAGATAATCTTAAACTAGAATGTTCAAAACTAATTGATAATTGAAGTATCAAGATACGTAGAACACCTCAGAGATTTTTCTTCAGGAA
CTTCCACAAACTTTGAATCCTTGTATCTTTATTTGGTATTCATACTACTAGTAGCAAAATACAGGTTTTTTGTTTTGTTTTGTTTTGTTT
TGGCTTCATAGAGTATCTCAAATTGAAACTTTTCTGCACAAAGAATAAAATTAAGGATTTTATAAACTCAAATTGGCACCTACTGAATTA
AAATACATAAAATCATTTAAATATAATTCAGCATATGGGAAGTAACATTGCACTAATATGGAAATCACTGCCAGAGACAGTCTATTTTCT
TTTAATTTGTTACTACTTAGTCACAAACCCCACATTATTCCAGTTTGGAATTACTTATTAAGGAGAATTGGAAATACATATGCCCATGCT
TAAATTTTATAGCTTTAATTTGTGTTATTTCTTTATTGACGGGAAGAGGTACATCTTTTTTTCCTTACTGAAAACAAATATGGATTAATT
GCCTCAAATTTGTATAAGTGATTGGCTAGTGATTCTTGTTTTCAGAAGGGAGAGTGGTATAGATAGAAAATGACAAAGATGGCAATATAC
ACTTAATGTTGTTATTGTATGTTGTTACTGAAGTACTTAGATTTTTAAAATTTCAAATCCTAAATCACTTCTTGTAGGAGGGTTTTCATT
AACTGCAGTATATACAGTTCACTACATATGGGTTGTTTGAGTTTTTTGTGTGCTGTATTTCTTTCTGTTTTTTAATACCTGGTTTTGTAC
ATATCTAACTCTGTTCTCTTTTGGTTGTTCAGAAACTGGATTTTTTTTTTCTTAAGCAGTGCTTAATTTGTGTTTTTTAATTTTGATTCA
GAAGTAGTCCCAGCTCATAGGTGTTCATACTGTTACATCCAGAACATTTGTCAGGCTCTCTGTCAGCTTTCATGTACATATGGTATAGAA
ACCATGGAGTTAGGCACTTCCTGGATTTTTTTTTTATGAGAAAAATACTGTATTTAAAATGTAAAATAAACTTTTAAAAAGCAGGCACTA
ATATATATTTCTTCCAGCCTTTGATTACAAATTTGTCCTTGCACATGTTAAGATGAATTATCTCCTAAAAATATCATTGTTCTTGGGAGC
AGTGTATGTTACTTTACATAGCAGCGGTTCCTGTCATGTGTTCATGTCAGAATATTTTTGGTTTTAAACTTTCTTATTGCCTTTGGCTGT

>27588_27588_1_ESRRG-ACBD3_ESRRG_chr1_216850418_ENST00000361395_ACBD3_chr1_226353701_ENST00000366812_length(amino acids)=577AA_BP=144
MRKGIRLLCRMSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPVRKLYDD
CSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQEKDGKAFHPTYEEKLKLVALHKQVLMGPYNPDTCPE
VGFFDVLGNDRRREWAALGNMSKEDAMVEFVKLLNRCCHLFSTYVASHKIEKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEER
LRREEEERRRIEEERLRLEQQKQQIMAALNSQTAVQFQQYAAQQYPGNYEQQQILIRQLQEQHYQQYMQQLYQVQLAQQQAALQKQQEVV
VAGSSLPTSSKVNATVPSNMMSVNGQAKTHTDSSEKELEPEAAEEALENGPKESLPVIAAPSMWTRPQIKDFKEKIQQDADSVITVGRGE
VVTVRVPTHEEGSYLFWEFATDNYDIGFGVYFEWTDSPNTAVSVHVSESSDDDEEEEENIGCEEKAKKNANKPLLDEIVPVYRRDCHEEV

--------------------------------------------------------------
>27588_27588_2_ESRRG-ACBD3_ESRRG_chr1_216850418_ENST00000408911_ACBD3_chr1_226353701_ENST00000366812_length(transcript)=3858nt_BP=626nt
AAGTCCTTGATTAGGAGAGTGTGAGAGCTTTGGTCCCAACTGGCTGTGCCTATAGGCTTGTCACTAGGAGAACATTTGTGTTAATTGCAC
TGTGCTCTGTCAAGGAAACTTTGATTTATAGCTGGGGTGCACAAATAATGGTTGCCGGTCGCACATGGATTCGGTAGAACTTTGCCTTCC
TGAATCTTTTTCCCTGCACTACGAGGAAGAGCTTCTCTGCAGAATGTCAAACAAAGATCGACACATTGATTCCAGCTGTTCGTCCTTCAT
CAAGACGGAACCTTCCAGCCCAGCCTCCCTGACGGACAGCGTCAACCACCACAGCCCTGGTGGCTCTTCAGACGCCAGTGGGAGCTACAG
TTCAACCATGAATGGCCATCAGAACGGACTTGACTCGCCACCTCTCTACCCTTCTGCTCCTATCCTGGGAGGTAGTGGGCCTGTCAGGAA
ACTGTATGATGACTGCTCCAGCACCATTGTTGAAGATCCCCAGACCAAGTGTGAATACATGCTCAACTCGATGCCCAAGAGACTGTGTTT
AGTGTGTGGTGACATCGCTTCTGGGTACCACTATGGGGTAGCATCATGTGAAGCCTGCAAGGCATTCTTCAAGAGGACAATTCAAGAAAA
AGATGGCAAAGCATTTCATCCAACTTATGAAGAAAAATTGAAGCTTGTGGCACTGCATAAGCAAGTTCTTATGGGCCCATATAATCCAGA
CACTTGTCCTGAGGTTGGATTCTTTGATGTGTTGGGGAATGACAGGAGGAGAGAATGGGCAGCCCTGGGAAACATGTCTAAAGAGGATGC
CATGGTGGAGTTTGTCAAGCTCTTAAATAGGTGTTGCCATCTCTTTTCAACATATGTTGCGTCCCACAAAATAGAGAAGGAAGAGCAAGA
AAAAAAAAGGAAGGAGGAAGAGGAGCGAAGGCGGCGTGAAGAGGAAGAAAGAGAACGTCTGCAAAAGGAGGAAGAGAAACGTAGGAGAGA
AGAAGAGGAAAGGCTTCGACGGGAGGAAGAGGAAAGGAGACGGATAGAAGAAGAAAGGCTTCGGTTGGAGCAGCAAAAGCAGCAGATAAT
GGCAGCTTTAAACTCCCAGACTGCCGTGCAGTTCCAGCAGTATGCAGCCCAACAGTATCCAGGGAACTACGAACAGCAGCAAATTCTCAT
CCGCCAGTTGCAGGAGCAACACTATCAGCAGTACATGCAGCAGTTGTATCAAGTCCAGCTTGCACAGCAACAGGCAGCATTACAGAAACA
ACAGGAAGTAGTAGTGGCTGGGTCTTCCTTGCCTACATCATCAAAAGTGAATGCAACTGTACCAAGTAATATGATGTCAGTTAATGGACA
GGCCAAAACACACACTGACAGCTCCGAAAAAGAACTGGAACCAGAAGCTGCAGAAGAAGCCCTGGAGAATGGACCAAAAGAATCTCTTCC
AGTAATAGCAGCTCCATCCATGTGGACACGACCTCAGATCAAAGACTTCAAAGAGAAGATTCAGCAGGATGCAGATTCCGTGATTACAGT
GGGCCGAGGAGAAGTGGTCACTGTTCGAGTACCCACCCATGAAGAAGGATCATATCTCTTTTGGGAATTTGCCACAGACAATTATGACAT
TGGGTTTGGGGTGTATTTTGAATGGACAGACTCTCCAAACACTGCTGTCAGCGTGCATGTCAGTGAGTCCAGCGATGACGACGAGGAGGA
AGAAGAAAACATCGGTTGTGAAGAGAAAGCCAAAAAGAATGCCAACAAGCCTTTGCTGGATGAGATTGTGCCTGTGTACCGACGGGACTG
TCATGAGGAGGTGTATGCTGGCAGCCATCAATATCCAGGGAGAGGAGTCTATCTCCTCAAGTTTGACAACTCCTACTCTTTGTGGCGGTC
AAAATCAGTCTACTACAGAGTCTATTATACTAGATAAAAATGTTGTTACAAAGTCTGGAGTCTAGGGTTGGGCAGAAGATGACATTTAAT
TTGGAAATTTCTTTTTACTTTTGTGGAGCATTAGAGTCACAGTTTACCTTATTGATATTGGTCTGATGGTTTGTGAACTCTTGCTGGGAA
TCAAAATTTCCTTGAGACTCTTTAGCATTCATACTTTGGGGTTAAAGGAGATTCCTCAGACTCATCCAGCCCTTGGGTGCTGACCAGCAG
AGTCACTAGTGGATGCTGAAGTTACATGAGCTACATGTTAAATATTTAAAGTCTCCAAAATAAAACACCCCAACGTTGACCTTACCCGGC
TGATGGTTAGCCCCTTGCTGCCTGCTCCATGTGTCTTATGAGAGCCCGTAGTTACAGTGTCCTCTAATTTGAAATCCATAAGTTAACAAG
TCTATATCAGGTGCAGCTGGCTTTGATTAAAGGCCATTTTTAAAACTTAAAAACTCAACACCTCACAGATTATAATAGAAAAAGAAATGG
CCTCAGTTTGATCTCGTTCAGAATGACCCAGATTGTTTCTGCTTTGGGTGCAGCTGTTTAGTTCAGAGTTATATTACAGAGAATTATTTT
CTGAGATAATCTTAAACTAGAATGTTCAAAACTAATTGATAATTGAAGTATCAAGATACGTAGAACACCTCAGAGATTTTTCTTCAGGAA
CTTCCACAAACTTTGAATCCTTGTATCTTTATTTGGTATTCATACTACTAGTAGCAAAATACAGGTTTTTTGTTTTGTTTTGTTTTGTTT
TGGCTTCATAGAGTATCTCAAATTGAAACTTTTCTGCACAAAGAATAAAATTAAGGATTTTATAAACTCAAATTGGCACCTACTGAATTA
AAATACATAAAATCATTTAAATATAATTCAGCATATGGGAAGTAACATTGCACTAATATGGAAATCACTGCCAGAGACAGTCTATTTTCT
TTTAATTTGTTACTACTTAGTCACAAACCCCACATTATTCCAGTTTGGAATTACTTATTAAGGAGAATTGGAAATACATATGCCCATGCT
TAAATTTTATAGCTTTAATTTGTGTTATTTCTTTATTGACGGGAAGAGGTACATCTTTTTTTCCTTACTGAAAACAAATATGGATTAATT
GCCTCAAATTTGTATAAGTGATTGGCTAGTGATTCTTGTTTTCAGAAGGGAGAGTGGTATAGATAGAAAATGACAAAGATGGCAATATAC
ACTTAATGTTGTTATTGTATGTTGTTACTGAAGTACTTAGATTTTTAAAATTTCAAATCCTAAATCACTTCTTGTAGGAGGGTTTTCATT
AACTGCAGTATATACAGTTCACTACATATGGGTTGTTTGAGTTTTTTGTGTGCTGTATTTCTTTCTGTTTTTTAATACCTGGTTTTGTAC
ATATCTAACTCTGTTCTCTTTTGGTTGTTCAGAAACTGGATTTTTTTTTTCTTAAGCAGTGCTTAATTTGTGTTTTTTAATTTTGATTCA
GAAGTAGTCCCAGCTCATAGGTGTTCATACTGTTACATCCAGAACATTTGTCAGGCTCTCTGTCAGCTTTCATGTACATATGGTATAGAA
ACCATGGAGTTAGGCACTTCCTGGATTTTTTTTTTATGAGAAAAATACTGTATTTAAAATGTAAAATAAACTTTTAAAAAGCAGGCACTA
ATATATATTTCTTCCAGCCTTTGATTACAAATTTGTCCTTGCACATGTTAAGATGAATTATCTCCTAAAAATATCATTGTTCTTGGGAGC
AGTGTATGTTACTTTACATAGCAGCGGTTCCTGTCATGTGTTCATGTCAGAATATTTTTGGTTTTAAACTTTCTTATTGCCTTTGGCTGT

>27588_27588_2_ESRRG-ACBD3_ESRRG_chr1_216850418_ENST00000408911_ACBD3_chr1_226353701_ENST00000366812_length(amino acids)=601AA_BP=168
MGCTNNGCRSHMDSVELCLPESFSLHYEEELLCRMSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGL
DSPPLYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQEKDGKAFHPTYE
EKLKLVALHKQVLMGPYNPDTCPEVGFFDVLGNDRRREWAALGNMSKEDAMVEFVKLLNRCCHLFSTYVASHKIEKEEQEKKRKEEEERR
RREEEERERLQKEEEKRRREEEERLRREEEERRRIEEERLRLEQQKQQIMAALNSQTAVQFQQYAAQQYPGNYEQQQILIRQLQEQHYQQ
YMQQLYQVQLAQQQAALQKQQEVVVAGSSLPTSSKVNATVPSNMMSVNGQAKTHTDSSEKELEPEAAEEALENGPKESLPVIAAPSMWTR
PQIKDFKEKIQQDADSVITVGRGEVVTVRVPTHEEGSYLFWEFATDNYDIGFGVYFEWTDSPNTAVSVHVSESSDDDEEEEENIGCEEKA

--------------------------------------------------------------
>27588_27588_3_ESRRG-ACBD3_ESRRG_chr1_216850418_ENST00000493748_ACBD3_chr1_226353701_ENST00000366812_length(transcript)=4250nt_BP=1018nt
ATTCTGGGCAAAGTGTGGTGACTTGTGGATTTTCACTGTGACGATGTTGCTACACGGTCCTTCACTTGGAGTTAGTGCAACAAGGAGACA
TCTGAGCTTAAAATTTATGAAACATCTAAAGAAATCAAGCTTTATATAGGATCACCGTTGTGGGTTGAATTGTGTATCCCCAAAAGATGT
TGAAGTCCTGACCACCTCCCTATACCTTACAATATAGCCTTTTACGGAAGTAGGGTCTTTGCAGAAGATCAAGTTAAGATGAAATCATTT
GATTGGGCCCTAGTTCAATATATCTTATGTCCTTATAAAAGGAGACAATTTGGACACAGGGACAAGGGGAGAATGCCACATAAAGATTGG
AATTATGCTGCCATAAGCCAAGGAACTCCAAAGATCGCTGGCAAGCTGCTAAAAGCTAGCACAGATTCATGGAACAGAGTCTCCGTCATA
GCCTACAAAAGGAATCAACCCTGCTGACATCTTGATTTCAGACTTCTAGCCTCCAGAACTAGCTGACAATTTACTGGTTCATCAATGAAA
CAATATTAAATTATGAAGATGTAAGGAAAAAATCCTACGCTAACACTGTCGCAGTTTGAAAGGCTTCTCTGCAGAATGTCAAACAAAGAT
CGACACATTGATTCCAGCTGTTCGTCCTTCATCAAGACGGAACCTTCCAGCCCAGCCTCCCTGACGGACAGCGTCAACCACCACAGCCCT
GGTGGCTCTTCAGACGCCAGTGGGAGCTACAGTTCAACCATGAATGGCCATCAGAACGGACTTGACTCGCCACCTCTCTACCCTTCTGCT
CCTATCCTGGGAGGTAGTGGGCCTGTCAGGAAACTGTATGATGACTGCTCCAGCACCATTGTTGAAGATCCCCAGACCAAGTGTGAATAC
ATGCTCAACTCGATGCCCAAGAGACTGTGTTTAGTGTGTGGTGACATCGCTTCTGGGTACCACTATGGGGTAGCATCATGTGAAGCCTGC
AAGGCATTCTTCAAGAGGACAATTCAAGAAAAAGATGGCAAAGCATTTCATCCAACTTATGAAGAAAAATTGAAGCTTGTGGCACTGCAT
AAGCAAGTTCTTATGGGCCCATATAATCCAGACACTTGTCCTGAGGTTGGATTCTTTGATGTGTTGGGGAATGACAGGAGGAGAGAATGG
GCAGCCCTGGGAAACATGTCTAAAGAGGATGCCATGGTGGAGTTTGTCAAGCTCTTAAATAGGTGTTGCCATCTCTTTTCAACATATGTT
GCGTCCCACAAAATAGAGAAGGAAGAGCAAGAAAAAAAAAGGAAGGAGGAAGAGGAGCGAAGGCGGCGTGAAGAGGAAGAAAGAGAACGT
CTGCAAAAGGAGGAAGAGAAACGTAGGAGAGAAGAAGAGGAAAGGCTTCGACGGGAGGAAGAGGAAAGGAGACGGATAGAAGAAGAAAGG
CTTCGGTTGGAGCAGCAAAAGCAGCAGATAATGGCAGCTTTAAACTCCCAGACTGCCGTGCAGTTCCAGCAGTATGCAGCCCAACAGTAT
CCAGGGAACTACGAACAGCAGCAAATTCTCATCCGCCAGTTGCAGGAGCAACACTATCAGCAGTACATGCAGCAGTTGTATCAAGTCCAG
CTTGCACAGCAACAGGCAGCATTACAGAAACAACAGGAAGTAGTAGTGGCTGGGTCTTCCTTGCCTACATCATCAAAAGTGAATGCAACT
GTACCAAGTAATATGATGTCAGTTAATGGACAGGCCAAAACACACACTGACAGCTCCGAAAAAGAACTGGAACCAGAAGCTGCAGAAGAA
GCCCTGGAGAATGGACCAAAAGAATCTCTTCCAGTAATAGCAGCTCCATCCATGTGGACACGACCTCAGATCAAAGACTTCAAAGAGAAG
ATTCAGCAGGATGCAGATTCCGTGATTACAGTGGGCCGAGGAGAAGTGGTCACTGTTCGAGTACCCACCCATGAAGAAGGATCATATCTC
TTTTGGGAATTTGCCACAGACAATTATGACATTGGGTTTGGGGTGTATTTTGAATGGACAGACTCTCCAAACACTGCTGTCAGCGTGCAT
GTCAGTGAGTCCAGCGATGACGACGAGGAGGAAGAAGAAAACATCGGTTGTGAAGAGAAAGCCAAAAAGAATGCCAACAAGCCTTTGCTG
GATGAGATTGTGCCTGTGTACCGACGGGACTGTCATGAGGAGGTGTATGCTGGCAGCCATCAATATCCAGGGAGAGGAGTCTATCTCCTC
AAGTTTGACAACTCCTACTCTTTGTGGCGGTCAAAATCAGTCTACTACAGAGTCTATTATACTAGATAAAAATGTTGTTACAAAGTCTGG
AGTCTAGGGTTGGGCAGAAGATGACATTTAATTTGGAAATTTCTTTTTACTTTTGTGGAGCATTAGAGTCACAGTTTACCTTATTGATAT
TGGTCTGATGGTTTGTGAACTCTTGCTGGGAATCAAAATTTCCTTGAGACTCTTTAGCATTCATACTTTGGGGTTAAAGGAGATTCCTCA
GACTCATCCAGCCCTTGGGTGCTGACCAGCAGAGTCACTAGTGGATGCTGAAGTTACATGAGCTACATGTTAAATATTTAAAGTCTCCAA
AATAAAACACCCCAACGTTGACCTTACCCGGCTGATGGTTAGCCCCTTGCTGCCTGCTCCATGTGTCTTATGAGAGCCCGTAGTTACAGT
GTCCTCTAATTTGAAATCCATAAGTTAACAAGTCTATATCAGGTGCAGCTGGCTTTGATTAAAGGCCATTTTTAAAACTTAAAAACTCAA
CACCTCACAGATTATAATAGAAAAAGAAATGGCCTCAGTTTGATCTCGTTCAGAATGACCCAGATTGTTTCTGCTTTGGGTGCAGCTGTT
TAGTTCAGAGTTATATTACAGAGAATTATTTTCTGAGATAATCTTAAACTAGAATGTTCAAAACTAATTGATAATTGAAGTATCAAGATA
CGTAGAACACCTCAGAGATTTTTCTTCAGGAACTTCCACAAACTTTGAATCCTTGTATCTTTATTTGGTATTCATACTACTAGTAGCAAA
ATACAGGTTTTTTGTTTTGTTTTGTTTTGTTTTGGCTTCATAGAGTATCTCAAATTGAAACTTTTCTGCACAAAGAATAAAATTAAGGAT
TTTATAAACTCAAATTGGCACCTACTGAATTAAAATACATAAAATCATTTAAATATAATTCAGCATATGGGAAGTAACATTGCACTAATA
TGGAAATCACTGCCAGAGACAGTCTATTTTCTTTTAATTTGTTACTACTTAGTCACAAACCCCACATTATTCCAGTTTGGAATTACTTAT
TAAGGAGAATTGGAAATACATATGCCCATGCTTAAATTTTATAGCTTTAATTTGTGTTATTTCTTTATTGACGGGAAGAGGTACATCTTT
TTTTCCTTACTGAAAACAAATATGGATTAATTGCCTCAAATTTGTATAAGTGATTGGCTAGTGATTCTTGTTTTCAGAAGGGAGAGTGGT
ATAGATAGAAAATGACAAAGATGGCAATATACACTTAATGTTGTTATTGTATGTTGTTACTGAAGTACTTAGATTTTTAAAATTTCAAAT
CCTAAATCACTTCTTGTAGGAGGGTTTTCATTAACTGCAGTATATACAGTTCACTACATATGGGTTGTTTGAGTTTTTTGTGTGCTGTAT
TTCTTTCTGTTTTTTAATACCTGGTTTTGTACATATCTAACTCTGTTCTCTTTTGGTTGTTCAGAAACTGGATTTTTTTTTTCTTAAGCA
GTGCTTAATTTGTGTTTTTTAATTTTGATTCAGAAGTAGTCCCAGCTCATAGGTGTTCATACTGTTACATCCAGAACATTTGTCAGGCTC
TCTGTCAGCTTTCATGTACATATGGTATAGAAACCATGGAGTTAGGCACTTCCTGGATTTTTTTTTTATGAGAAAAATACTGTATTTAAA
ATGTAAAATAAACTTTTAAAAAGCAGGCACTAATATATATTTCTTCCAGCCTTTGATTACAAATTTGTCCTTGCACATGTTAAGATGAAT
TATCTCCTAAAAATATCATTGTTCTTGGGAGCAGTGTATGTTACTTTACATAGCAGCGGTTCCTGTCATGTGTTCATGTCAGAATATTTT
TGGTTTTAAACTTTCTTATTGCCTTTGGCTGTTGATTAGTACAGTACAAGTGCGATTTCAAAAAGATCTTGAAAGTAATATATTTAATCA

>27588_27588_3_ESRRG-ACBD3_ESRRG_chr1_216850418_ENST00000493748_ACBD3_chr1_226353701_ENST00000366812_length(amino acids)=577AA_BP=144
MSQFERLLCRMSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPVRKLYDD
CSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQEKDGKAFHPTYEEKLKLVALHKQVLMGPYNPDTCPE
VGFFDVLGNDRRREWAALGNMSKEDAMVEFVKLLNRCCHLFSTYVASHKIEKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEER
LRREEEERRRIEEERLRLEQQKQQIMAALNSQTAVQFQQYAAQQYPGNYEQQQILIRQLQEQHYQQYMQQLYQVQLAQQQAALQKQQEVV
VAGSSLPTSSKVNATVPSNMMSVNGQAKTHTDSSEKELEPEAAEEALENGPKESLPVIAAPSMWTRPQIKDFKEKIQQDADSVITVGRGE
VVTVRVPTHEEGSYLFWEFATDNYDIGFGVYFEWTDSPNTAVSVHVSESSDDDEEEEENIGCEEKAKKNANKPLLDEIVPVYRRDCHEEV

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for ESRRG-ACBD3

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for ESRRG-ACBD3

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for ESRRG-ACBD3

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source

Fusion Gene Studies in Kim Lab

Fusion gene:ESRRG-ACBD3 (FusionGDB2 ID:HG2104TG64746)

Fusion Gene Summary for ESRRG-ACBD3

Fusion Gene ORF analysis for ESRRG-ACBD3

Fusion Genomic Features for ESRRG-ACBD3

Fusion Protein Features for ESRRG-ACBD3

Fusion Gene Sequence for ESRRG-ACBD3

Fusion Gene PPI Analysis for ESRRG-ACBD3

Related Drugs for ESRRG-ACBD3

Related Diseases for ESRRG-ACBD3

Fusion Gene Studies
in Kim Lab