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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Diseases

Fusion gene:EWSR1-ERG (FusionGDB2 ID:HG2130TG2078)

Fusion Gene Summary for EWSR1-ERG

check button Fusion gene summary
Fusion gene informationFusion gene name: EWSR1-ERG
Fusion gene ID: hg2130tg2078
HgeneTgene
Gene symbol

EWSR1

ERG

Gene ID

2130

2078

Gene nameEWS RNA binding protein 1ETS transcription factor ERG
SynonymsEWS|EWS-FLI1|bK984G1.4erg-3|p55
Cytomap('EWSR1')('ERG')

22q12.2

21q22.2

Type of geneprotein-codingprotein-coding
DescriptionRNA-binding protein EWSEWS RNA-binding protein variant 6Ewing sarcoma breakpoint region 1Ewings sarcoma EWS-Fli1 (type 1) oncogenetranscriptional regulator ERGERG, ETS transcription factorFUS/ERG fusion proteinTMPRSS2/ERG fusionerythroblast transformation-specific transcription factor ERG variant 10ets-relatedtranscriptional regulator ERG (transforming protein ERG)v-ets avian
Modification date2020032920200320
UniProtAcc

Q01844

P11308

Ensembl transtripts involved in fusion geneENST00000331029, ENST00000332035, 
ENST00000332050, ENST00000333395, 
ENST00000397938, ENST00000406548, 
ENST00000414183, 
ENST00000331029, 
ENST00000332035, ENST00000332050, 
ENST00000333395, ENST00000397938, 
ENST00000406548, ENST00000414183, 
Fusion gene scores* DoF score44 X 91 X 16=6406421 X 74 X 12=18648
# samples 9896
** MAII scorelog2(98/64064*10)=-6.03058831983342
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(96/18648*10)=-4.27984269352035
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EWSR1 [Title/Abstract] AND ERG [Title/Abstract] AND fusion [Title/Abstract]

Ewing sarcoma with ERG gene rearrangements: A molecular study focusing on the prevalence of FUS-ERG and common pitfalls in detecting EWSR1-ERG fusions by FISH (pmid: 26690869)
Most frequent breakpointEWSR1(29683123)-ERG(39764366), # samples:2
Anticipated loss of major functional domain due to fusion event.EWSR1-ERG seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
EWSR1-ERG seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
EWSR1-ERG seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
EWSR1-ERG seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ERG-EWSR1 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
ERG-EWSR1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ERG-EWSR1 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
ERG-EWSR1 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
ERG-EWSR1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
EWSR1-ERG seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
EWSR1-ERG seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
EWSR1-ERG seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
EWSR1-ERG seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
EWSR1-ERG seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneERG

GO:0045944

positive regulation of transcription by RNA polymerase II

18195090|23913826


check buttonFusion gene breakpoints across EWSR1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ERG (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4desmoplastic small round cell tumorS70579EWSR1chr22

29683123

ERGchr21

39764323

ChimerKB3..EWSR1chr22

29678546

+ERGchr21

39772567

-
ChimerKB3..EWSR1chr22

29678546

+ERGchr21

39774559

-
ChimerKB3..EWSR1chr22

29683123

+ERGchr21

39755343

-
ChimerKB3..EWSR1chr22

29683123

+ERGchr21

39764323

-
ChimerKB3..EWSR1chr22

29683123

+ERGchr21

39764366

-
ChimerKB3..EWSR1chr22

29683124

+ERGchr21

39755343

-
ChimerKB3..EWSR1chr22

29683124

+ERGchr21

39755802

-
ChimerKB3..EWSR1chr22

29687588

+ERGchr21

39772567

-
ChimerKB3..EWSR1chr22

29687588

+ERGchr21

39774559

-
ChimerKB4..EWSR1chr22

29678546

+ERGchr21

39774559

-


Top

Fusion Gene ORF analysis for EWSR1-ERG

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000331029ENST00000288319EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000331029ENST00000288319EWSR1chr22

29678546

+ERGchr21

39772567

-
5CDS-intronENST00000331029ENST00000288319EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000331029ENST00000288319EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000331029ENST00000398897EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000331029ENST00000398897EWSR1chr22

29678546

+ERGchr21

39772567

-
5CDS-intronENST00000331029ENST00000398897EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000331029ENST00000398897EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000331029ENST00000398905EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000331029ENST00000398905EWSR1chr22

29678546

+ERGchr21

39772567

-
5CDS-intronENST00000331029ENST00000398905EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000331029ENST00000398905EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000331029ENST00000398907EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000331029ENST00000398907EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000331029ENST00000398907EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000331029ENST00000398910EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000331029ENST00000398910EWSR1chr22

29678546

+ERGchr21

39772567

-
5CDS-intronENST00000331029ENST00000398910EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000331029ENST00000398910EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000331029ENST00000398911EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000331029ENST00000398911EWSR1chr22

29678546

+ERGchr21

39772567

-
5CDS-intronENST00000331029ENST00000398911EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000331029ENST00000398911EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000331029ENST00000398919EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000331029ENST00000398919EWSR1chr22

29678546

+ERGchr21

39772567

-
5CDS-intronENST00000331029ENST00000398919EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000331029ENST00000398919EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000331029ENST00000417133EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000331029ENST00000417133EWSR1chr22

29678546

+ERGchr21

39772567

-
5CDS-intronENST00000331029ENST00000417133EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000331029ENST00000417133EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000331029ENST00000429727EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000331029ENST00000429727EWSR1chr22

29678546

+ERGchr21

39772567

-
5CDS-intronENST00000331029ENST00000429727EWSR1chr22

29678546

+ERGchr21

39774559

-
5CDS-intronENST00000331029ENST00000429727EWSR1chr22

29683123

+ERGchr21

39755343

-
5CDS-intronENST00000331029ENST00000429727EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000331029ENST00000429727EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000331029ENST00000429727EWSR1chr22

29683124

+ERGchr21

39755343

-
5CDS-intronENST00000331029ENST00000429727EWSR1chr22

29683124

+ERGchr21

39755802

-
5CDS-intronENST00000331029ENST00000442448EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000331029ENST00000442448EWSR1chr22

29678546

+ERGchr21

39772567

-
5CDS-intronENST00000331029ENST00000442448EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000331029ENST00000442448EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000331029ENST00000453032EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000331029ENST00000453032EWSR1chr22

29678546

+ERGchr21

39772567

-
5CDS-intronENST00000331029ENST00000453032EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000331029ENST00000453032EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000331029ENST00000485493EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000331029ENST00000485493EWSR1chr22

29678546

+ERGchr21

39772567

-
5CDS-intronENST00000331029ENST00000485493EWSR1chr22

29678546

+ERGchr21

39774559

-
5CDS-intronENST00000331029ENST00000485493EWSR1chr22

29683123

+ERGchr21

39755343

-
5CDS-intronENST00000331029ENST00000485493EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000331029ENST00000485493EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000331029ENST00000485493EWSR1chr22

29683124

+ERGchr21

39755343

-
5CDS-intronENST00000331029ENST00000485493EWSR1chr22

29683124

+ERGchr21

39755802

-
5CDS-intronENST00000332035ENST00000288319EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332035ENST00000288319EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332035ENST00000288319EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332035ENST00000288319EWSR1chr22

29687588

+ERGchr21

39772567

-
5CDS-intronENST00000332035ENST00000398897EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332035ENST00000398897EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332035ENST00000398897EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332035ENST00000398897EWSR1chr22

29687588

+ERGchr21

39772567

-
5CDS-intronENST00000332035ENST00000398905EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332035ENST00000398905EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332035ENST00000398905EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332035ENST00000398905EWSR1chr22

29687588

+ERGchr21

39772567

-
5CDS-intronENST00000332035ENST00000398907EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332035ENST00000398907EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332035ENST00000398907EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332035ENST00000398910EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332035ENST00000398910EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332035ENST00000398910EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332035ENST00000398910EWSR1chr22

29687588

+ERGchr21

39772567

-
5CDS-intronENST00000332035ENST00000398911EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332035ENST00000398911EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332035ENST00000398911EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332035ENST00000398911EWSR1chr22

29687588

+ERGchr21

39772567

-
5CDS-intronENST00000332035ENST00000398919EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332035ENST00000398919EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332035ENST00000398919EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332035ENST00000398919EWSR1chr22

29687588

+ERGchr21

39772567

-
5CDS-intronENST00000332035ENST00000417133EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332035ENST00000417133EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332035ENST00000417133EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332035ENST00000417133EWSR1chr22

29687588

+ERGchr21

39772567

-
5CDS-intronENST00000332035ENST00000429727EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332035ENST00000429727EWSR1chr22

29683123

+ERGchr21

39755343

-
5CDS-intronENST00000332035ENST00000429727EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332035ENST00000429727EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332035ENST00000429727EWSR1chr22

29683124

+ERGchr21

39755343

-
5CDS-intronENST00000332035ENST00000429727EWSR1chr22

29683124

+ERGchr21

39755802

-
5CDS-intronENST00000332035ENST00000429727EWSR1chr22

29687588

+ERGchr21

39772567

-
5CDS-intronENST00000332035ENST00000429727EWSR1chr22

29687588

+ERGchr21

39774559

-
5CDS-intronENST00000332035ENST00000442448EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332035ENST00000442448EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332035ENST00000442448EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332035ENST00000442448EWSR1chr22

29687588

+ERGchr21

39772567

-
5CDS-intronENST00000332035ENST00000453032EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332035ENST00000453032EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332035ENST00000453032EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332035ENST00000453032EWSR1chr22

29687588

+ERGchr21

39772567

-
5CDS-intronENST00000332035ENST00000485493EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332035ENST00000485493EWSR1chr22

29683123

+ERGchr21

39755343

-
5CDS-intronENST00000332035ENST00000485493EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332035ENST00000485493EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332035ENST00000485493EWSR1chr22

29683124

+ERGchr21

39755343

-
5CDS-intronENST00000332035ENST00000485493EWSR1chr22

29683124

+ERGchr21

39755802

-
5CDS-intronENST00000332035ENST00000485493EWSR1chr22

29687588

+ERGchr21

39772567

-
5CDS-intronENST00000332035ENST00000485493EWSR1chr22

29687588

+ERGchr21

39774559

-
5CDS-intronENST00000332050ENST00000288319EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332050ENST00000288319EWSR1chr22

29678546

+ERGchr21

39772567

-
5CDS-intronENST00000332050ENST00000288319EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332050ENST00000288319EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332050ENST00000398897EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332050ENST00000398897EWSR1chr22

29678546

+ERGchr21

39772567

-
5CDS-intronENST00000332050ENST00000398897EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332050ENST00000398897EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332050ENST00000398905EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332050ENST00000398905EWSR1chr22

29678546

+ERGchr21

39772567

-
5CDS-intronENST00000332050ENST00000398905EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332050ENST00000398905EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332050ENST00000398907EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332050ENST00000398907EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332050ENST00000398907EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332050ENST00000398910EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332050ENST00000398910EWSR1chr22

29678546

+ERGchr21

39772567

-
5CDS-intronENST00000332050ENST00000398910EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332050ENST00000398910EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332050ENST00000398911EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332050ENST00000398911EWSR1chr22

29678546

+ERGchr21

39772567

-
5CDS-intronENST00000332050ENST00000398911EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332050ENST00000398911EWSR1chr22

29683123

+ERGchr21

39764366

-
5CDS-intronENST00000332050ENST00000398919EWSR1chr22

29683123

ERGchr21

39764323

5CDS-intronENST00000332050ENST00000398919EWSR1chr22

29678546

+ERGchr21

39772567

-
5CDS-intronENST00000332050ENST00000398919EWSR1chr22

29683123

+ERGchr21

39764323

-
5CDS-intronENST00000332050ENST00000398919EWSR1chr22

29683123

+ERGchr21

39764366

-
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39774559

-
In-frameENST00000406548ENST00000398911EWSR1chr22

29683123

+ERGchr21

39755343

-
In-frameENST00000406548ENST00000398911EWSR1chr22

29683124

+ERGchr21

39755343

-
In-frameENST00000406548ENST00000398911EWSR1chr22

29683124

+ERGchr21

39755802

-
In-frameENST00000406548ENST00000398911EWSR1chr22

29687588

+ERGchr21

39774559

-
In-frameENST00000406548ENST00000398919EWSR1chr22

29687588

+ERGchr21

39774559

-
In-frameENST00000406548ENST00000417133EWSR1chr22

29683123

+ERGchr21

39755343

-
In-frameENST00000406548ENST00000417133EWSR1chr22

29683124

+ERGchr21

39755343

-
In-frameENST00000406548ENST00000417133EWSR1chr22

29683124

+ERGchr21

39755802

-
In-frameENST00000406548ENST00000417133EWSR1chr22

29687588

+ERGchr21

39774559

-
In-frameENST00000406548ENST00000442448EWSR1chr22

29687588

+ERGchr21

39774559

-
In-frameENST00000406548ENST00000453032EWSR1chr22

29683123

+ERGchr21

39755343

-
In-frameENST00000406548ENST00000453032EWSR1chr22

29683124

+ERGchr21

39755343

-
In-frameENST00000406548ENST00000453032EWSR1chr22

29683124

+ERGchr21

39755802

-
In-frameENST00000406548ENST00000453032EWSR1chr22

29687588

+ERGchr21

39774559

-
In-frameENST00000414183ENST00000288319EWSR1chr22

29687588

+ERGchr21

39774559

-
In-frameENST00000414183ENST00000398897EWSR1chr22

29683123

+ERGchr21

39755343

-
In-frameENST00000414183ENST00000398897EWSR1chr22

29683124

+ERGchr21

39755343

-
In-frameENST00000414183ENST00000398897EWSR1chr22

29683124

+ERGchr21

39755802

-
In-frameENST00000414183ENST00000398897EWSR1chr22

29687588

+ERGchr21

39774559

-
In-frameENST00000414183ENST00000398905EWSR1chr22

29687588

+ERGchr21

39774559

-
In-frameENST00000414183ENST00000398907EWSR1chr22

29687588

+ERGchr21

39772567

-
In-frameENST00000414183ENST00000398907EWSR1chr22

29687588

+ERGchr21

39774559

-
In-frameENST00000414183ENST00000398910EWSR1chr22

29683123

+ERGchr21

39755343

-
In-frameENST00000414183ENST00000398910EWSR1chr22

29683124

+ERGchr21

39755343

-
In-frameENST00000414183ENST00000398910EWSR1chr22

29683124

+ERGchr21

39755802

-
In-frameENST00000414183ENST00000398910EWSR1chr22

29687588

+ERGchr21

39774559

-
In-frameENST00000414183ENST00000398911EWSR1chr22

29683123

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39755343

-
In-frameENST00000414183ENST00000398911EWSR1chr22

29683124

+ERGchr21

39755343

-
In-frameENST00000414183ENST00000398911EWSR1chr22

29683124

+ERGchr21

39755802

-
In-frameENST00000414183ENST00000398911EWSR1chr22

29687588

+ERGchr21

39774559

-
In-frameENST00000414183ENST00000398919EWSR1chr22

29687588

+ERGchr21

39774559

-
In-frameENST00000414183ENST00000417133EWSR1chr22

29683123

+ERGchr21

39755343

-
In-frameENST00000414183ENST00000417133EWSR1chr22

29683124

+ERGchr21

39755343

-
In-frameENST00000414183ENST00000417133EWSR1chr22

29683124

+ERGchr21

39755802

-
In-frameENST00000414183ENST00000417133EWSR1chr22

29687588

+ERGchr21

39774559

-
In-frameENST00000414183ENST00000442448EWSR1chr22

29687588

+ERGchr21

39774559

-
In-frameENST00000414183ENST00000453032EWSR1chr22

29683123

+ERGchr21

39755343

-
In-frameENST00000414183ENST00000453032EWSR1chr22

29683124

+ERGchr21

39755343

-
In-frameENST00000414183ENST00000453032EWSR1chr22

29683124

+ERGchr21

39755802

-
In-frameENST00000414183ENST00000453032EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000331029ENST00000288319EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000331029ENST00000398897EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000331029ENST00000398905EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000331029ENST00000398907EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-3CDSENST00000331029ENST00000398907EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000331029ENST00000398910EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000331029ENST00000398911EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000331029ENST00000398919EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000331029ENST00000417133EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000331029ENST00000442448EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000331029ENST00000453032EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000332035ENST00000288319EWSR1chr22

29678546

+ERGchr21

39774559

-
intron-3CDSENST00000332035ENST00000398897EWSR1chr22

29678546

+ERGchr21

39774559

-
intron-3CDSENST00000332035ENST00000398905EWSR1chr22

29678546

+ERGchr21

39774559

-
intron-3CDSENST00000332035ENST00000398907EWSR1chr22

29678546

+ERGchr21

39772567

-
intron-3CDSENST00000332035ENST00000398907EWSR1chr22

29678546

+ERGchr21

39774559

-
intron-3CDSENST00000332035ENST00000398910EWSR1chr22

29678546

+ERGchr21

39774559

-
intron-3CDSENST00000332035ENST00000398911EWSR1chr22

29678546

+ERGchr21

39774559

-
intron-3CDSENST00000332035ENST00000398919EWSR1chr22

29678546

+ERGchr21

39774559

-
intron-3CDSENST00000332035ENST00000417133EWSR1chr22

29678546

+ERGchr21

39774559

-
intron-3CDSENST00000332035ENST00000442448EWSR1chr22

29678546

+ERGchr21

39774559

-
intron-3CDSENST00000332035ENST00000453032EWSR1chr22

29678546

+ERGchr21

39774559

-
intron-3CDSENST00000332050ENST00000288319EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000332050ENST00000398897EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000332050ENST00000398905EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000332050ENST00000398907EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-3CDSENST00000332050ENST00000398907EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000332050ENST00000398910EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000332050ENST00000398911EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000332050ENST00000398919EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000332050ENST00000417133EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000332050ENST00000442448EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000332050ENST00000453032EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000333395ENST00000288319EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000333395ENST00000398897EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000333395ENST00000398905EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000333395ENST00000398907EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-3CDSENST00000333395ENST00000398907EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000333395ENST00000398910EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000333395ENST00000398911EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000333395ENST00000398919EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000333395ENST00000417133EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000333395ENST00000442448EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-3CDSENST00000333395ENST00000453032EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-intronENST00000331029ENST00000288319EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000331029ENST00000398897EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000331029ENST00000398905EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000331029ENST00000398910EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000331029ENST00000398911EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000331029ENST00000398919EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000331029ENST00000417133EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000331029ENST00000429727EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000331029ENST00000429727EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-intronENST00000331029ENST00000442448EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000331029ENST00000453032EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000331029ENST00000485493EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000331029ENST00000485493EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-intronENST00000332035ENST00000288319EWSR1chr22

29678546

+ERGchr21

39772567

-
intron-intronENST00000332035ENST00000398897EWSR1chr22

29678546

+ERGchr21

39772567

-
intron-intronENST00000332035ENST00000398905EWSR1chr22

29678546

+ERGchr21

39772567

-
intron-intronENST00000332035ENST00000398910EWSR1chr22

29678546

+ERGchr21

39772567

-
intron-intronENST00000332035ENST00000398911EWSR1chr22

29678546

+ERGchr21

39772567

-
intron-intronENST00000332035ENST00000398919EWSR1chr22

29678546

+ERGchr21

39772567

-
intron-intronENST00000332035ENST00000417133EWSR1chr22

29678546

+ERGchr21

39772567

-
intron-intronENST00000332035ENST00000429727EWSR1chr22

29678546

+ERGchr21

39772567

-
intron-intronENST00000332035ENST00000429727EWSR1chr22

29678546

+ERGchr21

39774559

-
intron-intronENST00000332035ENST00000442448EWSR1chr22

29678546

+ERGchr21

39772567

-
intron-intronENST00000332035ENST00000453032EWSR1chr22

29678546

+ERGchr21

39772567

-
intron-intronENST00000332035ENST00000485493EWSR1chr22

29678546

+ERGchr21

39772567

-
intron-intronENST00000332035ENST00000485493EWSR1chr22

29678546

+ERGchr21

39774559

-
intron-intronENST00000332050ENST00000288319EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000332050ENST00000398897EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000332050ENST00000398905EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000332050ENST00000398910EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000332050ENST00000398911EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000332050ENST00000398919EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000332050ENST00000417133EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000332050ENST00000429727EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000332050ENST00000429727EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-intronENST00000332050ENST00000442448EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000332050ENST00000453032EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000332050ENST00000485493EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000332050ENST00000485493EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-intronENST00000333395ENST00000288319EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000333395ENST00000398897EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000333395ENST00000398905EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000333395ENST00000398910EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000333395ENST00000398911EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000333395ENST00000398919EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000333395ENST00000417133EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000333395ENST00000429727EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000333395ENST00000429727EWSR1chr22

29687588

+ERGchr21

39774559

-
intron-intronENST00000333395ENST00000442448EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000333395ENST00000453032EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000333395ENST00000485493EWSR1chr22

29687588

+ERGchr21

39772567

-
intron-intronENST00000333395ENST00000485493EWSR1chr22

29687588

+ERGchr21

39774559

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000332050EWSR1chr2229683123+ENST00000398897ERGchr2139755343-451611213281212294
ENST00000332050EWSR1chr2229683123+ENST00000398911ERGchr2139755343-451611213281212294
ENST00000332050EWSR1chr2229683123+ENST00000398910ERGchr2139755343-451611213281212294
ENST00000332050EWSR1chr2229683123+ENST00000417133ERGchr2139755343-451611213281212294
ENST00000332050EWSR1chr2229683123+ENST00000453032ERGchr2139755343-141711213281212294
ENST00000397938EWSR1chr2229683123+ENST00000398897ERGchr2139755343-450711123191203294
ENST00000397938EWSR1chr2229683123+ENST00000398911ERGchr2139755343-450711123191203294
ENST00000397938EWSR1chr2229683123+ENST00000398910ERGchr2139755343-450711123191203294
ENST00000397938EWSR1chr2229683123+ENST00000417133ERGchr2139755343-450711123191203294
ENST00000397938EWSR1chr2229683123+ENST00000453032ERGchr2139755343-140811123191203294
ENST00000406548EWSR1chr2229683123+ENST00000398897ERGchr2139755343-425285764948294
ENST00000406548EWSR1chr2229683123+ENST00000398911ERGchr2139755343-425285764948294
ENST00000406548EWSR1chr2229683123+ENST00000398910ERGchr2139755343-425285764948294
ENST00000406548EWSR1chr2229683123+ENST00000417133ERGchr2139755343-425285764948294
ENST00000406548EWSR1chr2229683123+ENST00000453032ERGchr2139755343-115385764948294
ENST00000331029EWSR1chr2229683123+ENST00000398897ERGchr2139755343-423483946930294
ENST00000331029EWSR1chr2229683123+ENST00000398911ERGchr2139755343-423483946930294
ENST00000331029EWSR1chr2229683123+ENST00000398910ERGchr2139755343-423483946930294
ENST00000331029EWSR1chr2229683123+ENST00000417133ERGchr2139755343-423483946930294
ENST00000331029EWSR1chr2229683123+ENST00000453032ERGchr2139755343-113583946930294
ENST00000414183EWSR1chr2229683123+ENST00000398897ERGchr2139755343-422783221923300
ENST00000414183EWSR1chr2229683123+ENST00000398911ERGchr2139755343-422783221923300
ENST00000414183EWSR1chr2229683123+ENST00000398910ERGchr2139755343-422783221923300
ENST00000414183EWSR1chr2229683123+ENST00000417133ERGchr2139755343-422783221923300
ENST00000414183EWSR1chr2229683123+ENST00000453032ERGchr2139755343-112883221923300
ENST00000333395EWSR1chr2229683123+ENST00000398897ERGchr2139755343-420781219903294
ENST00000333395EWSR1chr2229683123+ENST00000398911ERGchr2139755343-420781219903294
ENST00000333395EWSR1chr2229683123+ENST00000398910ERGchr2139755343-420781219903294
ENST00000333395EWSR1chr2229683123+ENST00000417133ERGchr2139755343-420781219903294
ENST00000333395EWSR1chr2229683123+ENST00000453032ERGchr2139755343-110881219903294
ENST00000332035EWSR1chr2229683123+ENST00000398897ERGchr2139755343-403163611727238
ENST00000332035EWSR1chr2229683123+ENST00000398911ERGchr2139755343-403163611727238
ENST00000332035EWSR1chr2229683123+ENST00000398910ERGchr2139755343-403163611727238
ENST00000332035EWSR1chr2229683123+ENST00000417133ERGchr2139755343-403163611727238
ENST00000332035EWSR1chr2229683123+ENST00000453032ERGchr2139755343-93263611727238
ENST00000332050EWSR1chr2229683124+ENST00000398897ERGchr2139755343-451611213281212294
ENST00000332050EWSR1chr2229683124+ENST00000398911ERGchr2139755343-451611213281212294
ENST00000332050EWSR1chr2229683124+ENST00000398910ERGchr2139755343-451611213281212294
ENST00000332050EWSR1chr2229683124+ENST00000417133ERGchr2139755343-451611213281212294
ENST00000332050EWSR1chr2229683124+ENST00000453032ERGchr2139755343-141711213281212294
ENST00000397938EWSR1chr2229683124+ENST00000398897ERGchr2139755343-450711123191203294
ENST00000397938EWSR1chr2229683124+ENST00000398911ERGchr2139755343-450711123191203294
ENST00000397938EWSR1chr2229683124+ENST00000398910ERGchr2139755343-450711123191203294
ENST00000397938EWSR1chr2229683124+ENST00000417133ERGchr2139755343-450711123191203294
ENST00000397938EWSR1chr2229683124+ENST00000453032ERGchr2139755343-140811123191203294
ENST00000406548EWSR1chr2229683124+ENST00000398897ERGchr2139755343-425285764948294
ENST00000406548EWSR1chr2229683124+ENST00000398911ERGchr2139755343-425285764948294
ENST00000406548EWSR1chr2229683124+ENST00000398910ERGchr2139755343-425285764948294
ENST00000406548EWSR1chr2229683124+ENST00000417133ERGchr2139755343-425285764948294
ENST00000406548EWSR1chr2229683124+ENST00000453032ERGchr2139755343-115385764948294
ENST00000331029EWSR1chr2229683124+ENST00000398897ERGchr2139755343-423483946930294
ENST00000331029EWSR1chr2229683124+ENST00000398911ERGchr2139755343-423483946930294
ENST00000331029EWSR1chr2229683124+ENST00000398910ERGchr2139755343-423483946930294
ENST00000331029EWSR1chr2229683124+ENST00000417133ERGchr2139755343-423483946930294
ENST00000331029EWSR1chr2229683124+ENST00000453032ERGchr2139755343-113583946930294
ENST00000414183EWSR1chr2229683124+ENST00000398897ERGchr2139755343-422783221923300
ENST00000414183EWSR1chr2229683124+ENST00000398911ERGchr2139755343-422783221923300
ENST00000414183EWSR1chr2229683124+ENST00000398910ERGchr2139755343-422783221923300
ENST00000414183EWSR1chr2229683124+ENST00000417133ERGchr2139755343-422783221923300
ENST00000414183EWSR1chr2229683124+ENST00000453032ERGchr2139755343-112883221923300
ENST00000333395EWSR1chr2229683124+ENST00000398897ERGchr2139755343-420781219903294
ENST00000333395EWSR1chr2229683124+ENST00000398911ERGchr2139755343-420781219903294
ENST00000333395EWSR1chr2229683124+ENST00000398910ERGchr2139755343-420781219903294
ENST00000333395EWSR1chr2229683124+ENST00000417133ERGchr2139755343-420781219903294
ENST00000333395EWSR1chr2229683124+ENST00000453032ERGchr2139755343-110881219903294
ENST00000332035EWSR1chr2229683124+ENST00000398897ERGchr2139755343-403163611727238
ENST00000332035EWSR1chr2229683124+ENST00000398911ERGchr2139755343-403163611727238
ENST00000332035EWSR1chr2229683124+ENST00000398910ERGchr2139755343-403163611727238
ENST00000332035EWSR1chr2229683124+ENST00000417133ERGchr2139755343-403163611727238
ENST00000332035EWSR1chr2229683124+ENST00000453032ERGchr2139755343-93263611727238
ENST00000332050EWSR1chr2229683124+ENST00000398897ERGchr2139755802-497511213281182284
ENST00000332050EWSR1chr2229683124+ENST00000398911ERGchr2139755802-497511213281182284
ENST00000332050EWSR1chr2229683124+ENST00000398910ERGchr2139755802-497511213281182284
ENST00000332050EWSR1chr2229683124+ENST00000417133ERGchr2139755802-497511213281182284
ENST00000332050EWSR1chr2229683124+ENST00000453032ERGchr2139755802-187611213281182284
ENST00000397938EWSR1chr2229683124+ENST00000398897ERGchr2139755802-496611123191173284
ENST00000397938EWSR1chr2229683124+ENST00000398911ERGchr2139755802-496611123191173284
ENST00000397938EWSR1chr2229683124+ENST00000398910ERGchr2139755802-496611123191173284
ENST00000397938EWSR1chr2229683124+ENST00000417133ERGchr2139755802-496611123191173284
ENST00000397938EWSR1chr2229683124+ENST00000453032ERGchr2139755802-186711123191173284
ENST00000406548EWSR1chr2229683124+ENST00000398897ERGchr2139755802-471185764918284
ENST00000406548EWSR1chr2229683124+ENST00000398911ERGchr2139755802-471185764918284
ENST00000406548EWSR1chr2229683124+ENST00000398910ERGchr2139755802-471185764918284
ENST00000406548EWSR1chr2229683124+ENST00000417133ERGchr2139755802-471185764918284
ENST00000406548EWSR1chr2229683124+ENST00000453032ERGchr2139755802-161285764918284
ENST00000331029EWSR1chr2229683124+ENST00000398897ERGchr2139755802-469383946900284
ENST00000331029EWSR1chr2229683124+ENST00000398911ERGchr2139755802-469383946900284
ENST00000331029EWSR1chr2229683124+ENST00000398910ERGchr2139755802-469383946900284
ENST00000331029EWSR1chr2229683124+ENST00000417133ERGchr2139755802-469383946900284
ENST00000331029EWSR1chr2229683124+ENST00000453032ERGchr2139755802-159483946900284
ENST00000414183EWSR1chr2229683124+ENST00000398897ERGchr2139755802-468683221893290
ENST00000414183EWSR1chr2229683124+ENST00000398911ERGchr2139755802-468683221893290
ENST00000414183EWSR1chr2229683124+ENST00000398910ERGchr2139755802-468683221893290
ENST00000414183EWSR1chr2229683124+ENST00000417133ERGchr2139755802-468683221893290
ENST00000414183EWSR1chr2229683124+ENST00000453032ERGchr2139755802-158783221893290
ENST00000333395EWSR1chr2229683124+ENST00000398897ERGchr2139755802-466681219873284
ENST00000333395EWSR1chr2229683124+ENST00000398911ERGchr2139755802-466681219873284
ENST00000333395EWSR1chr2229683124+ENST00000398910ERGchr2139755802-466681219873284
ENST00000333395EWSR1chr2229683124+ENST00000417133ERGchr2139755802-466681219873284
ENST00000333395EWSR1chr2229683124+ENST00000453032ERGchr2139755802-156781219873284
ENST00000332035EWSR1chr2229683124+ENST00000398897ERGchr2139755802-449063645764239
ENST00000332035EWSR1chr2229683124+ENST00000398911ERGchr2139755802-449063645764239
ENST00000332035EWSR1chr2229683124+ENST00000398910ERGchr2139755802-449063645764239
ENST00000332035EWSR1chr2229683124+ENST00000417133ERGchr2139755802-449063645764239
ENST00000332035EWSR1chr2229683124+ENST00000453032ERGchr2139755802-139163645764239
ENST00000397938EWSR1chr2229687588+ENST00000398907ERGchr2139772567-540513313192028569
ENST00000406548EWSR1chr2229687588+ENST00000398907ERGchr2139772567-51471073641770568
ENST00000414183EWSR1chr2229687588+ENST00000398907ERGchr2139772567-51221048211745574
ENST00000332035EWSR1chr2229687588+ENST00000398907ERGchr2139772567-4929855111552513
ENST00000397938EWSR1chr2229687588+ENST00000398907ERGchr2139774559-548613313192109596
ENST00000397938EWSR1chr2229687588+ENST00000398905ERGchr2139774559-548313313192106595
ENST00000397938EWSR1chr2229687588+ENST00000288319ERGchr2139774559-555513313192178619
ENST00000397938EWSR1chr2229687588+ENST00000398897ERGchr2139774559-548313313192106595
ENST00000397938EWSR1chr2229687588+ENST00000398911ERGchr2139774559-548313313192106595
ENST00000397938EWSR1chr2229687588+ENST00000398910ERGchr2139774559-548613313192109596
ENST00000397938EWSR1chr2229687588+ENST00000417133ERGchr2139774559-555513313192178619
ENST00000397938EWSR1chr2229687588+ENST00000442448ERGchr2139774559-548013313192106595
ENST00000397938EWSR1chr2229687588+ENST00000453032ERGchr2139774559-245613313192178619
ENST00000397938EWSR1chr2229687588+ENST00000398919ERGchr2139774559-229113313192178619
ENST00000406548EWSR1chr2229687588+ENST00000398907ERGchr2139774559-52281073641851595
ENST00000406548EWSR1chr2229687588+ENST00000398905ERGchr2139774559-52251073641848594
ENST00000406548EWSR1chr2229687588+ENST00000288319ERGchr2139774559-52971073641920618
ENST00000406548EWSR1chr2229687588+ENST00000398897ERGchr2139774559-52251073641848594
ENST00000406548EWSR1chr2229687588+ENST00000398911ERGchr2139774559-52251073641848594
ENST00000406548EWSR1chr2229687588+ENST00000398910ERGchr2139774559-52281073641851595
ENST00000406548EWSR1chr2229687588+ENST00000417133ERGchr2139774559-52971073641920618
ENST00000406548EWSR1chr2229687588+ENST00000442448ERGchr2139774559-52221073641848594
ENST00000406548EWSR1chr2229687588+ENST00000453032ERGchr2139774559-21981073641920618
ENST00000406548EWSR1chr2229687588+ENST00000398919ERGchr2139774559-20331073641920618
ENST00000414183EWSR1chr2229687588+ENST00000398907ERGchr2139774559-52031048211826601
ENST00000414183EWSR1chr2229687588+ENST00000398905ERGchr2139774559-52001048211823600
ENST00000414183EWSR1chr2229687588+ENST00000288319ERGchr2139774559-52721048211895624
ENST00000414183EWSR1chr2229687588+ENST00000398897ERGchr2139774559-52001048211823600
ENST00000414183EWSR1chr2229687588+ENST00000398911ERGchr2139774559-52001048211823600
ENST00000414183EWSR1chr2229687588+ENST00000398910ERGchr2139774559-52031048211826601
ENST00000414183EWSR1chr2229687588+ENST00000417133ERGchr2139774559-52721048211895624
ENST00000414183EWSR1chr2229687588+ENST00000442448ERGchr2139774559-51971048211823600
ENST00000414183EWSR1chr2229687588+ENST00000453032ERGchr2139774559-21731048211895624
ENST00000414183EWSR1chr2229687588+ENST00000398919ERGchr2139774559-20081048211895624
ENST00000332035EWSR1chr2229687588+ENST00000398907ERGchr2139774559-5010855111633540
ENST00000332035EWSR1chr2229687588+ENST00000398905ERGchr2139774559-5007855111630539
ENST00000332035EWSR1chr2229687588+ENST00000288319ERGchr2139774559-5079855111702563
ENST00000332035EWSR1chr2229687588+ENST00000398897ERGchr2139774559-5007855111630539
ENST00000332035EWSR1chr2229687588+ENST00000398911ERGchr2139774559-5007855111630539
ENST00000332035EWSR1chr2229687588+ENST00000398910ERGchr2139774559-5010855111633540
ENST00000332035EWSR1chr2229687588+ENST00000417133ERGchr2139774559-5079855111702563
ENST00000332035EWSR1chr2229687588+ENST00000442448ERGchr2139774559-5004855111630539
ENST00000332035EWSR1chr2229687588+ENST00000453032ERGchr2139774559-1980855111702563
ENST00000332035EWSR1chr2229687588+ENST00000398919ERGchr2139774559-1815855111702563

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000332050ENST00000398897EWSR1chr2229683124+ERGchr2139755845-0.0009504430.9990496
ENST00000332050ENST00000398911EWSR1chr2229683124+ERGchr2139755845-0.0009504430.9990496
ENST00000332050ENST00000398910EWSR1chr2229683124+ERGchr2139755845-0.0009504430.9990496
ENST00000332050ENST00000417133EWSR1chr2229683124+ERGchr2139755845-0.0009504430.9990496
ENST00000332050ENST00000453032EWSR1chr2229683124+ERGchr2139755845-0.0080113760.9919886
ENST00000397938ENST00000398897EWSR1chr2229683124+ERGchr2139755845-0.0009365990.99906343
ENST00000397938ENST00000398911EWSR1chr2229683124+ERGchr2139755845-0.0009365990.99906343
ENST00000397938ENST00000398910EWSR1chr2229683124+ERGchr2139755845-0.0009365990.99906343
ENST00000397938ENST00000417133EWSR1chr2229683124+ERGchr2139755845-0.0009365990.99906343
ENST00000397938ENST00000453032EWSR1chr2229683124+ERGchr2139755845-0.0074642950.9925357
ENST00000406548ENST00000398897EWSR1chr2229683124+ERGchr2139755845-0.0008928650.99910706
ENST00000406548ENST00000398911EWSR1chr2229683124+ERGchr2139755845-0.0008928650.99910706
ENST00000406548ENST00000398910EWSR1chr2229683124+ERGchr2139755845-0.0008928650.99910706
ENST00000406548ENST00000417133EWSR1chr2229683124+ERGchr2139755845-0.0008928650.99910706
ENST00000406548ENST00000453032EWSR1chr2229683124+ERGchr2139755845-0.0091010680.99089897
ENST00000331029ENST00000398897EWSR1chr2229683124+ERGchr2139755845-0.0009036610.9990964
ENST00000331029ENST00000398911EWSR1chr2229683124+ERGchr2139755845-0.0009036610.9990964
ENST00000331029ENST00000398910EWSR1chr2229683124+ERGchr2139755845-0.0009036610.9990964
ENST00000331029ENST00000417133EWSR1chr2229683124+ERGchr2139755845-0.0009036610.9990964
ENST00000331029ENST00000453032EWSR1chr2229683124+ERGchr2139755845-0.0088168240.99118316
ENST00000414183ENST00000398897EWSR1chr2229683124+ERGchr2139755845-0.0008508150.9991492
ENST00000414183ENST00000398911EWSR1chr2229683124+ERGchr2139755845-0.0008508150.9991492
ENST00000414183ENST00000398910EWSR1chr2229683124+ERGchr2139755845-0.0008508150.9991492
ENST00000414183ENST00000417133EWSR1chr2229683124+ERGchr2139755845-0.0008508150.9991492
ENST00000414183ENST00000453032EWSR1chr2229683124+ERGchr2139755845-0.0076534760.9923465
ENST00000333395ENST00000398897EWSR1chr2229683124+ERGchr2139755845-0.0008787460.99912125
ENST00000333395ENST00000398911EWSR1chr2229683124+ERGchr2139755845-0.0008787460.99912125
ENST00000333395ENST00000398910EWSR1chr2229683124+ERGchr2139755845-0.0008787460.99912125
ENST00000333395ENST00000417133EWSR1chr2229683124+ERGchr2139755845-0.0008787460.99912125
ENST00000333395ENST00000453032EWSR1chr2229683124+ERGchr2139755845-0.0077346860.99226534
ENST00000332035ENST00000398897EWSR1chr2229683124+ERGchr2139755845-0.001182760.99881727
ENST00000332035ENST00000398911EWSR1chr2229683124+ERGchr2139755845-0.001182760.99881727
ENST00000332035ENST00000398910EWSR1chr2229683124+ERGchr2139755845-0.001182760.99881727
ENST00000332035ENST00000417133EWSR1chr2229683124+ERGchr2139755845-0.001182760.99881727
ENST00000332035ENST00000453032EWSR1chr2229683124+ERGchr2139755845-0.0092839690.9907161
ENST00000332050ENST00000398907EWSR1chr2229682944+ERGchr2139762958-0.0007195520.9992805
ENST00000332050ENST00000398905EWSR1chr2229682944+ERGchr2139762958-0.0007195520.9992805
ENST00000332050ENST00000288319EWSR1chr2229682944+ERGchr2139762958-0.0007195520.9992805
ENST00000332050ENST00000398897EWSR1chr2229682944+ERGchr2139762958-0.0007195520.9992805
ENST00000332050ENST00000398911EWSR1chr2229682944+ERGchr2139762958-0.0007195520.9992805
ENST00000332050ENST00000398910EWSR1chr2229682944+ERGchr2139762958-0.0007195520.9992805
ENST00000332050ENST00000417133EWSR1chr2229682944+ERGchr2139762958-0.0007195520.9992805
ENST00000332050ENST00000442448EWSR1chr2229682944+ERGchr2139762958-0.0007177490.9992823
ENST00000332050ENST00000453032EWSR1chr2229682944+ERGchr2139762958-0.0062120950.9937878
ENST00000332050ENST00000398919EWSR1chr2229682944+ERGchr2139762958-0.0082526520.9917474
ENST00000397938ENST00000398907EWSR1chr2229682944+ERGchr2139762958-0.000709040.99929094
ENST00000397938ENST00000398905EWSR1chr2229682944+ERGchr2139762958-0.000709040.99929094
ENST00000397938ENST00000288319EWSR1chr2229682944+ERGchr2139762958-0.000709040.99929094
ENST00000397938ENST00000398897EWSR1chr2229682944+ERGchr2139762958-0.000709040.99929094
ENST00000397938ENST00000398911EWSR1chr2229682944+ERGchr2139762958-0.000709040.99929094
ENST00000397938ENST00000398910EWSR1chr2229682944+ERGchr2139762958-0.000709040.99929094
ENST00000397938ENST00000417133EWSR1chr2229682944+ERGchr2139762958-0.000709040.99929094
ENST00000397938ENST00000442448EWSR1chr2229682944+ERGchr2139762958-0.0007072630.99929273
ENST00000397938ENST00000453032EWSR1chr2229682944+ERGchr2139762958-0.0056855410.9943145
ENST00000397938ENST00000398919EWSR1chr2229682944+ERGchr2139762958-0.0075671140.99243283
ENST00000406548ENST00000398907EWSR1chr2229682944+ERGchr2139762958-0.0006728960.9993272
ENST00000406548ENST00000398905EWSR1chr2229682944+ERGchr2139762958-0.0006728960.9993272
ENST00000406548ENST00000288319EWSR1chr2229682944+ERGchr2139762958-0.0006728960.9993272
ENST00000406548ENST00000398897EWSR1chr2229682944+ERGchr2139762958-0.0006728960.9993272
ENST00000406548ENST00000398911EWSR1chr2229682944+ERGchr2139762958-0.0006728960.9993272
ENST00000406548ENST00000398910EWSR1chr2229682944+ERGchr2139762958-0.0006728960.9993272
ENST00000406548ENST00000417133EWSR1chr2229682944+ERGchr2139762958-0.0006728960.9993272
ENST00000406548ENST00000442448EWSR1chr2229682944+ERGchr2139762958-0.0006706990.9993293
ENST00000406548ENST00000453032EWSR1chr2229682944+ERGchr2139762958-0.0065012660.9934988
ENST00000406548ENST00000398919EWSR1chr2229682944+ERGchr2139762958-0.007884670.9921153
ENST00000331029ENST00000398907EWSR1chr2229682944+ERGchr2139762958-0.0006807810.9993192
ENST00000331029ENST00000398905EWSR1chr2229682944+ERGchr2139762958-0.0006807810.9993192
ENST00000331029ENST00000288319EWSR1chr2229682944+ERGchr2139762958-0.0006807810.9993192
ENST00000331029ENST00000398897EWSR1chr2229682944+ERGchr2139762958-0.0006807810.9993192
ENST00000331029ENST00000398911EWSR1chr2229682944+ERGchr2139762958-0.0006807810.9993192
ENST00000331029ENST00000398910EWSR1chr2229682944+ERGchr2139762958-0.0006807810.9993192
ENST00000331029ENST00000417133EWSR1chr2229682944+ERGchr2139762958-0.0006807810.9993192
ENST00000331029ENST00000442448EWSR1chr2229682944+ERGchr2139762958-0.0006785750.99932146
ENST00000331029ENST00000453032EWSR1chr2229682944+ERGchr2139762958-0.0062189520.99378103
ENST00000331029ENST00000398919EWSR1chr2229682944+ERGchr2139762958-0.00730030.9926997
ENST00000414183ENST00000398907EWSR1chr2229682944+ERGchr2139762958-0.0010154350.9989845
ENST00000414183ENST00000398905EWSR1chr2229682944+ERGchr2139762958-0.0010154350.9989845
ENST00000414183ENST00000288319EWSR1chr2229682944+ERGchr2139762958-0.0010154350.9989845
ENST00000414183ENST00000398897EWSR1chr2229682944+ERGchr2139762958-0.0010154350.9989845
ENST00000414183ENST00000398911EWSR1chr2229682944+ERGchr2139762958-0.0010154350.9989845
ENST00000414183ENST00000398910EWSR1chr2229682944+ERGchr2139762958-0.0010154350.9989845
ENST00000414183ENST00000417133EWSR1chr2229682944+ERGchr2139762958-0.0010154350.9989845
ENST00000414183ENST00000442448EWSR1chr2229682944+ERGchr2139762958-0.001012940.998987
ENST00000414183ENST00000453032EWSR1chr2229682944+ERGchr2139762958-0.0078558410.9921442
ENST00000414183ENST00000398919EWSR1chr2229682944+ERGchr2139762958-0.0085142450.9914858
ENST00000333395ENST00000398907EWSR1chr2229682944+ERGchr2139762958-0.0006618180.9993382
ENST00000333395ENST00000398905EWSR1chr2229682944+ERGchr2139762958-0.0006618180.9993382
ENST00000333395ENST00000288319EWSR1chr2229682944+ERGchr2139762958-0.0006618180.9993382
ENST00000333395ENST00000398897EWSR1chr2229682944+ERGchr2139762958-0.0006618180.9993382
ENST00000333395ENST00000398911EWSR1chr2229682944+ERGchr2139762958-0.0006618180.9993382
ENST00000333395ENST00000398910EWSR1chr2229682944+ERGchr2139762958-0.0006618180.9993382
ENST00000333395ENST00000417133EWSR1chr2229682944+ERGchr2139762958-0.0006618180.9993382
ENST00000333395ENST00000442448EWSR1chr2229682944+ERGchr2139762958-0.0006596790.99934036
ENST00000333395ENST00000453032EWSR1chr2229682944+ERGchr2139762958-0.0054119740.994588
ENST00000333395ENST00000398919EWSR1chr2229682944+ERGchr2139762958-0.0062086520.9937914
ENST00000332035ENST00000398907EWSR1chr2229682944+ERGchr2139762958-0.0007111020.9992889
ENST00000332035ENST00000398905EWSR1chr2229682944+ERGchr2139762958-0.0007111020.9992889
ENST00000332035ENST00000288319EWSR1chr2229682944+ERGchr2139762958-0.0007111020.9992889
ENST00000332035ENST00000398897EWSR1chr2229682944+ERGchr2139762958-0.0007111020.9992889
ENST00000332035ENST00000398911EWSR1chr2229682944+ERGchr2139762958-0.0007111020.9992889
ENST00000332035ENST00000398910EWSR1chr2229682944+ERGchr2139762958-0.0007111020.9992889
ENST00000332035ENST00000417133EWSR1chr2229682944+ERGchr2139762958-0.0007111020.9992889
ENST00000332035ENST00000442448EWSR1chr2229682944+ERGchr2139762958-0.0007004190.9992995
ENST00000332035ENST00000453032EWSR1chr2229682944+ERGchr2139762958-0.0050669340.99493307
ENST00000332035ENST00000398919EWSR1chr2229682944+ERGchr2139762958-0.0045839580.99541605

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Fusion Genomic Features for EWSR1-ERG


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for EWSR1-ERG


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:29683123/chr21:39764366)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EWSR1

Q01844

ERG

P11308

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+616111_116208601.0RepeatNote=12
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+616117_125208601.0RepeatNote=13
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+616126_156208601.0RepeatNote=14
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+616157_163208601.0RepeatNote=15
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+616164_170208601.0RepeatNote=16
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+616171_177208601.0RepeatNote=17
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+616178_188208601.0RepeatNote=18
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+61617_27208601.0RepeatNote=2
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+616189_193208601.0RepeatNote=19
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+616194_201208601.0RepeatNote=20
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+616202_206208601.0RepeatNote=21
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+61628_34208601.0RepeatNote=3
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+61635_42208601.0RepeatNote=4
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+61643_50208601.0RepeatNote=5
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+61651_59208601.0RepeatNote=6
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+61660_68208601.0RepeatNote=7
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+61669_75208601.0RepeatNote=8
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+61676_84208601.0RepeatNote=9
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+61685_91208601.0RepeatNote=10
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+6168_16208601.0RepeatNote=1
HgeneEWSR1chr22:29683124chr21:39755845ENST00000332035+61692_110208601.0RepeatNote=11
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79111_116264355.0RepeatNote=12
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79117_125264355.0RepeatNote=13
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79126_156264355.0RepeatNote=14
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79157_163264355.0RepeatNote=15
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79164_170264355.0RepeatNote=16
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79171_177264355.0RepeatNote=17
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79178_188264355.0RepeatNote=18
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+7917_27264355.0RepeatNote=2
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79189_193264355.0RepeatNote=19
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79194_201264355.0RepeatNote=20
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79202_206264355.0RepeatNote=21
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79207_212264355.0RepeatNote=22
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79213_218264355.0RepeatNote=23
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79219_224264355.0RepeatNote=24
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79225_230264355.0RepeatNote=25
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79231_238264355.0RepeatNote=26
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79239_245264355.0RepeatNote=27
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79246_252264355.0RepeatNote=28
HgeneEWSR1chr22:29683124chr21:39755845ENST00000333395+79253_259264355.0RepeatNote=29
HgeneEWSR1