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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FGFR3-TACC3 (FusionGDB2 ID:HG2261TG10460)

Fusion Gene Summary for FGFR3-TACC3

check button Fusion gene summary
Fusion gene informationFusion gene name: FGFR3-TACC3
Fusion gene ID: hg2261tg10460
HgeneTgene
Gene symbol

FGFR3

TACC3

Gene ID

2261

10460

Gene namefibroblast growth factor receptor 3transforming acidic coiled-coil containing protein 3
SynonymsACH|CD333|CEK2|HSFGFR3EX|JTK4ERIC-1|ERIC1|Tacc4|maskin
Cytomap('FGFR3')('TACC3')

4p16.3

4p16.3

Type of geneprotein-codingprotein-coding
Descriptionfibroblast growth factor receptor 3FGFR-3fibroblast growth factor receptor 3 variant 4fibroblast growth factor receptor 3-Shydroxyaryl-protein kinasetyrosine kinase JTK4transforming acidic coiled-coil-containing protein 3
Modification date2020031320200327
UniProtAcc

P22607

Q9Y6A5

Ensembl transtripts involved in fusion geneENST00000474521, ENST00000260795, 
ENST00000340107, ENST00000352904, 
ENST00000412135, ENST00000440486, 
ENST00000481110, 
ENST00000474521, 
ENST00000260795, ENST00000340107, 
ENST00000352904, ENST00000412135, 
ENST00000440486, ENST00000481110, 
Fusion gene scores* DoF score10 X 22 X 14=308012 X 26 X 14=4368
# samples 3331
** MAII scorelog2(33/3080*10)=-3.22239242133645
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(31/4368*10)=-3.81663273564562
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FGFR3 [Title/Abstract] AND TACC3 [Title/Abstract] AND fusion [Title/Abstract]

Transforming fusions of FGFR and TACC genes in human glioblastoma. (pmid: 22837387)
Most frequent breakpointFGFR3(1808661)-TACC3(1741429), # samples:88
Anticipated loss of major functional domain due to fusion event.FGFR3-TACC3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
FGFR3-TACC3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
FGFR3-TACC3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
FGFR3-TACC3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
TACC3-FGFR3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
TACC3-FGFR3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
FGFR3-TACC3 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
FGFR3-TACC3 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
FGFR3-TACC3 seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF.
TACC3-FGFR3 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
TACC3-FGFR3 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
TACC3-FGFR3 seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFGFR3

GO:0008543

fibroblast growth factor receptor signaling pathway

8663044

HgeneFGFR3

GO:0018108

peptidyl-tyrosine phosphorylation

11294897

HgeneFGFR3

GO:0046777

protein autophosphorylation

11294897


check buttonFusion gene breakpoints across FGFR3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across TACC3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-CF-A3MF-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4BLCATCGA-CF-A3MF-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4BLCATCGA-CF-A3MF-01AFGFR3chr4

1808925

+TACC3chr4

1741371

+
ChimerDB4BLCATCGA-CF-A3MG-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4BLCATCGA-CF-A3MG-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4BLCATCGA-CF-A3MH-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4BLCATCGA-CF-A3MH-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4BLCATCGA-CF-A47S-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4BLCATCGA-CF-A47S-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4BLCATCGA-CF-A47T-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4BLCATCGA-CF-A47T-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4BLCATCGA-CF-A8HY-01AFGFR3chr4

1808660

+TACC3chr4

1737457

+
ChimerDB4BLCATCGA-CF-A8HY-01AFGFR3chr4

1808661

-TACC3chr4

1737458

+
ChimerDB4BLCATCGA-CF-A8HY-01AFGFR3chr4

1808661

+TACC3chr4

1737458

+
ChimerDB4BLCATCGA-E7-A5KE-01AFGFR3chr4

1808660

+TACC3chr4

1741428

+
ChimerDB4BLCATCGA-E7-A5KE-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4BLCATCGA-E7-A5KE-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4BLCATCGA-XF-AAMX-01AFGFR3chr4

1795770

-TACC3chr4

1746245

+
ChimerDB4BLCATCGA-XF-AAMX-01AFGFR3chr4

1795770

+TACC3chr4

1746245

+
ChimerDB4BLCATCGA-XF-AAMXFGFR3chr4

1795770

+TACC3chr4

1746245

+
ChimerDB4BLCATCGA-XF-AAMZ-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4BLCATCGA-XF-AAMZ-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4BLCATCGA-XF-AAMZFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4CESCTCGA-DS-A3LQ-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4CESCTCGA-DS-A3LQ-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4CESCTCGA-LP-A7HU-01AFGFR3chr4

1808661

-TACC3chr4

1737458

+
ChimerDB4CESCTCGA-Q1-A73R-01AFGFR3chr4

1808947

+TACC3chr4

1742621

+
ChimerDB4CESCTCGA-VS-A9UD-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4CESCTCGA-VS-A9UD-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4CESCTCGA-VS-A9UDFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4CESCTCGA-WL-A834-01AFGFR3chr4

1808660

+TACC3chr4

1737457

+
ChimerDB4CESCTCGA-WL-A834-01AFGFR3chr4

1808661

-TACC3chr4

1737458

+
ChimerDB4CESCTCGA-WL-A834-01AFGFR3chr4

1808661

+TACC3chr4

1737458

+
ChimerDB4CESCTCGA-ZJ-AAXT-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4CESCTCGA-ZJ-AAXT-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4CESCTCGA-ZJ-AAXTFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4ESCATCGA-LN-A5U5-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4ESCATCGA-LN-A5U5-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4ESCATCGA-LN-A5U5FGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4ESCATCGA-LN-A9FO-01AFGFR3chr4

1808661

-TACC3chr4

1737458

+
ChimerDB4ESCATCGA-LN-A9FO-01AFGFR3chr4

1808661

+TACC3chr4

1737458

+
ChimerDB4ESCATCGA-LN-A9FOFGFR3chr4

1808661

+TACC3chr4

1737458

+
ChimerDB4GBMTCGA-02-2486-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-06-2557-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-06-2558-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-06-2559-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-06-2561-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-06-2564-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-06-2567-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4GBMTCGA-06-2567-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-06-2570FGFR3chr4

1808661

+TACC3chr4

1741428

+
ChimerDB4GBMTCGA-12-0821-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-14-0787-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-14-0789-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4GBMTCGA-14-0789-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-14-1034-02BFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-14-1402-02AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-14-1823-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4GBMTCGA-14-1823-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-14-1825-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-14-1825FGFR3chr4

1808661

+TACC3chr4

1741428

+
ChimerDB4GBMTCGA-14-1829-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4GBMTCGA-14-1829-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-16-0846-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-16-1045FGFR3chr4

1808661

+TACC3chr4

1741428

+
ChimerDB4GBMTCGA-19-0957-02AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-19-1389-02AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-27-1831-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-27-1832-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-27-1832FGFR3chr4

1808661

+TACC3chr4

1741428

+
ChimerDB4GBMTCGA-27-1835-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4GBMTCGA-27-1835-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-27-1835FGFR3chr4

1808661

+TACC3chr4

1741428

+
ChimerDB4GBMTCGA-27-1837-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-27-1837FGFR3chr4

1808661

+TACC3chr4

1741428

+
ChimerDB4GBMTCGA-27-2519-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-27-2521-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-27-2523-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-27-2526-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4GBMTCGA-76-4925-01AFGFR3chr4

1808661

-TACC3chr4

1739325

+
ChimerDB4GBMTCGA-76-4925-01AFGFR3chr4

1808661

+TACC3chr4

1739325

+
ChimerDB4GBMTCGA-76-4925FGFR3chr4

1808661

+TACC3chr4

1739324

+
ChimerDB4HNSCTCGA-CR-6473-01AFGFR3chr4

1808661

-TACC3chr4

1739325

+
ChimerDB4HNSCTCGA-CR-6473-01AFGFR3chr4

1808661

+TACC3chr4

1739325

+
ChimerDB4HNSCTCGA-CR-6473FGFR3chr4

1808661

+TACC3chr4

1739325

+
ChimerDB4HNSCTCGA-CV-7100-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4HNSCTCGA-CV-7100-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4HNSCTCGA-CV-7100FGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4HNSCTCGA-CV-7100FGFR3chr4

1808922

+TACC3chr4

1741371

+
ChimerDB4KIRPTCGA-A4-7287-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4KIRPTCGA-A4-7287-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4KIRPTCGA-A4-7287FGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4KIRPTCGA-DW-7839-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4KIRPTCGA-DW-7839-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4LAMLTCGA-AB-2920-03BFGFR3chr4

1807798

+TACC3chr4

1729971

+
ChimerDB4LGGTCGA-FG-7643-01AFGFR3chr4

1808660

+TACC3chr4

1741428

+
ChimerDB4LGGTCGA-FG-7643-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4LGGTCGA-FG-7643-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4LGGTCGA-FG-7643FGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4LGGTCGA-P5-A72U-01AFGFR3chr4

1808660

+TACC3chr4

1732898

+
ChimerDB4LGGTCGA-P5-A72U-01AFGFR3chr4

1808661

-TACC3chr4

1732899

+
ChimerDB4LGGTCGA-P5-A72U-01AFGFR3chr4

1808661

+TACC3chr4

1732899

+
ChimerDB4LGGTCGA-P5-A72UFGFR3chr4

1808661

+TACC3chr4

1732899

+
ChimerDB4LIHCTCGA-CC-A3M9-01AFGFR3chr4

1801539

+TACC3chr4

1746245

+
ChimerDB4LIHCTCGA-DD-A1EK-01AFGFR3chr4

1801539

-TACC3chr4

1746245

+
ChimerDB4LIHCTCGA-DD-A1EK-01AFGFR3chr4

1801539

+TACC3chr4

1746245

+
ChimerDB4LUADTCGA-38-4630-01AFGFR3chr4

1801250

+TACC3chr4

1729435

+
ChimerDB4LUADTCGA-38-4630-01AFGFR3chr4

1803470

-TACC3chr4

1746245

+
ChimerDB4LUSCTCGA-22-4607-01AFGFR3chr4

1808661

-TACC3chr4

1737000

+
ChimerDB4LUSCTCGA-22-4607-01AFGFR3chr4

1808661

+TACC3chr4

1737000

+
ChimerDB4LUSCTCGA-22-4607FGFR3chr4

1808661

+TACC3chr4

1737000

+
ChimerDB4LUSCTCGA-22-4607FGFR3chr4

1808738

+TACC3chr4

1734261

+
ChimerDB4LUSCTCGA-34-2608-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4LUSCTCGA-34-2608-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4LUSCTCGA-34-2608FGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4LUSCTCGA-39-5024-01AFGFR3chr4

1808650

+TACC3chr4

1737483

+
ChimerDB4LUSCTCGA-39-5024-01AFGFR3chr4

1808660

+TACC3chr4

1741428

+
ChimerDB4LUSCTCGA-39-5024-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4LUSCTCGA-39-5024-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4LUSCTCGA-39-5024FGFR3chr4

1808651

+TACC3chr4

1737484

+
ChimerDB4LUSCTCGA-39-5024FGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4LUSCTCGA-63-7022-01AFGFR3chr4

1808661

-TACC3chr4

1746245

+
ChimerDB4LUSCTCGA-63-7022-01AFGFR3chr4

1808661

+TACC3chr4

1746245

+
ChimerDB4LUSCTCGA-66-2786-01AFGFR3chr4

1808660

+TACC3chr4

1741428

+
ChimerDB4LUSCTCGA-66-2786-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4LUSCTCGA-66-2786-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4LUSCTCGA-66-2786FGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4LUSCTCGA-92-8065-01AFGFR3chr4

1808661

-TACC3chr4

1741429

+
ChimerDB4LUSCTCGA-92-8065-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4LUSCTCGA-92-8065FGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerDB4LUSCTCGA-92-8065FGFR3chr4

1808661

+TACC3chr4

1746245

+
ChimerDB4STADTCGA-BR-8058-01AFGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerKB3..FGFR3chr4

1808410

+TACC3chr4

1737457

+
ChimerKB3..FGFR3chr4

1808661

+TACC3chr4

1741429

+
ChimerKB3..FGFR3chr4

1810599

+TACC3chr4

1737457

+
ChimerKB3..FGFR3chr4

1810599

+TACC3chr4

1741428

+


Top

Fusion Gene ORF analysis for FGFR3-TACC3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000474521ENST00000313288FGFR3chr4

1803470

-TACC3chr4

1746245

+
5CDS-intronENST00000260795ENST00000313288FGFR3chr4

1808925

+TACC3chr4

1741371

+
5CDS-intronENST00000260795ENST00000313288FGFR3chr4

1808922

+TACC3chr4

1741371

+
5CDS-intronENST00000340107ENST00000313288FGFR3chr4

1808925

+TACC3chr4

1741371

+
5CDS-intronENST00000340107ENST00000313288FGFR3chr4

1808922

+TACC3chr4

1741371

+
5CDS-intronENST00000352904ENST00000313288FGFR3chr4

1808925

+TACC3chr4

1741371

+
5CDS-intronENST00000352904ENST00000313288FGFR3chr4

1808922

+TACC3chr4

1741371

+
5CDS-intronENST00000412135ENST00000313288FGFR3chr4

1808925

+TACC3chr4

1741371

+
5CDS-intronENST00000412135ENST00000313288FGFR3chr4

1808922

+TACC3chr4

1741371

+
5CDS-intronENST00000440486ENST00000313288FGFR3chr4

1808925

+TACC3chr4

1741371

+
5CDS-intronENST00000440486ENST00000313288FGFR3chr4

1808922

+TACC3chr4

1741371

+
5CDS-intronENST00000481110ENST00000313288FGFR3chr4

1808925

+TACC3chr4

1741371

+
5CDS-intronENST00000481110ENST00000313288FGFR3chr4

1808922

+TACC3chr4

1741371

+
Frame-shiftENST00000260795ENST00000313288FGFR3chr4

1795770

+TACC3chr4

1746245

+
Frame-shiftENST00000260795ENST00000313288FGFR3chr4

1807798

+TACC3chr4

1729971

+
Frame-shiftENST00000260795ENST00000313288FGFR3chr4

1801539

+TACC3chr4

1746245

+
Frame-shiftENST00000260795ENST00000313288FGFR3chr4

1801250

+TACC3chr4

1729435

+
Frame-shiftENST00000260795ENST00000313288FGFR3chr4

1803470

-TACC3chr4

1746245

+
Frame-shiftENST00000260795ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1737000

+
Frame-shiftENST00000260795ENST00000313288FGFR3chr4

1808410

+TACC3chr4

1737457

+
Frame-shiftENST00000260795ENST00000313288FGFR3chr4

1810599

+TACC3chr4

1737457

+
Frame-shiftENST00000260795ENST00000313288FGFR3chr4

1810599

+TACC3chr4

1741428

+
Frame-shiftENST00000340107ENST00000313288FGFR3chr4

1795770

+TACC3chr4

1746245

+
Frame-shiftENST00000340107ENST00000313288FGFR3chr4

1808947

+TACC3chr4

1742621

+
Frame-shiftENST00000340107ENST00000313288FGFR3chr4

1807798

+TACC3chr4

1729971

+
Frame-shiftENST00000340107ENST00000313288FGFR3chr4

1801539

+TACC3chr4

1746245

+
Frame-shiftENST00000340107ENST00000313288FGFR3chr4

1801250

+TACC3chr4

1729435

+
Frame-shiftENST00000340107ENST00000313288FGFR3chr4

1803470

-TACC3chr4

1746245

+
Frame-shiftENST00000340107ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1737000

+
Frame-shiftENST00000340107ENST00000313288FGFR3chr4

1808410

+TACC3chr4

1737457

+
Frame-shiftENST00000340107ENST00000313288FGFR3chr4

1810599

+TACC3chr4

1737457

+
Frame-shiftENST00000340107ENST00000313288FGFR3chr4

1810599

+TACC3chr4

1741428

+
Frame-shiftENST00000352904ENST00000313288FGFR3chr4

1795770

+TACC3chr4

1746245

+
Frame-shiftENST00000352904ENST00000313288FGFR3chr4

1807798

+TACC3chr4

1729971

+
Frame-shiftENST00000352904ENST00000313288FGFR3chr4

1801539

+TACC3chr4

1746245

+
Frame-shiftENST00000352904ENST00000313288FGFR3chr4

1801250

+TACC3chr4

1729435

+
Frame-shiftENST00000352904ENST00000313288FGFR3chr4

1803470

-TACC3chr4

1746245

+
Frame-shiftENST00000352904ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1737000

+
Frame-shiftENST00000352904ENST00000313288FGFR3chr4

1808410

+TACC3chr4

1737457

+
Frame-shiftENST00000352904ENST00000313288FGFR3chr4

1810599

+TACC3chr4

1737457

+
Frame-shiftENST00000352904ENST00000313288FGFR3chr4

1810599

+TACC3chr4

1741428

+
Frame-shiftENST00000412135ENST00000313288FGFR3chr4

1795770

+TACC3chr4

1746245

+
Frame-shiftENST00000412135ENST00000313288FGFR3chr4

1808947

+TACC3chr4

1742621

+
Frame-shiftENST00000412135ENST00000313288FGFR3chr4

1807798

+TACC3chr4

1729971

+
Frame-shiftENST00000412135ENST00000313288FGFR3chr4

1801539

+TACC3chr4

1746245

+
Frame-shiftENST00000412135ENST00000313288FGFR3chr4

1801250

+TACC3chr4

1729435

+
Frame-shiftENST00000412135ENST00000313288FGFR3chr4

1803470

-TACC3chr4

1746245

+
Frame-shiftENST00000412135ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1737000

+
Frame-shiftENST00000412135ENST00000313288FGFR3chr4

1808410

+TACC3chr4

1737457

+
Frame-shiftENST00000412135ENST00000313288FGFR3chr4

1810599

+TACC3chr4

1737457

+
Frame-shiftENST00000412135ENST00000313288FGFR3chr4

1810599

+TACC3chr4

1741428

+
Frame-shiftENST00000440486ENST00000313288FGFR3chr4

1795770

+TACC3chr4

1746245

+
Frame-shiftENST00000440486ENST00000313288FGFR3chr4

1808947

+TACC3chr4

1742621

+
Frame-shiftENST00000440486ENST00000313288FGFR3chr4

1807798

+TACC3chr4

1729971

+
Frame-shiftENST00000440486ENST00000313288FGFR3chr4

1801539

+TACC3chr4

1746245

+
Frame-shiftENST00000440486ENST00000313288FGFR3chr4

1801250

+TACC3chr4

1729435

+
Frame-shiftENST00000440486ENST00000313288FGFR3chr4

1803470

-TACC3chr4

1746245

+
Frame-shiftENST00000440486ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1737000

+
Frame-shiftENST00000440486ENST00000313288FGFR3chr4

1808410

+TACC3chr4

1737457

+
Frame-shiftENST00000440486ENST00000313288FGFR3chr4

1810599

+TACC3chr4

1737457

+
Frame-shiftENST00000440486ENST00000313288FGFR3chr4

1810599

+TACC3chr4

1741428

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1741429

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1737458

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1795770

+TACC3chr4

1746245

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1808947

+TACC3chr4

1742621

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1737457

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1741428

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1739324

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1739325

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1807798

+TACC3chr4

1729971

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1741428

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1732898

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1732899

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1801539

+TACC3chr4

1746245

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1801250

+TACC3chr4

1729435

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1803470

-TACC3chr4

1746245

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1808650

+TACC3chr4

1737483

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1808651

+TACC3chr4

1737484

+
Frame-shiftENST00000481110ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1746245

+
In-frameENST00000260795ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1741429

+
In-frameENST00000260795ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1737458

+
In-frameENST00000260795ENST00000313288FGFR3chr4

1808947

+TACC3chr4

1742621

+
In-frameENST00000260795ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1737457

+
In-frameENST00000260795ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1741428

+
In-frameENST00000260795ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1739324

+
In-frameENST00000260795ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1739325

+
In-frameENST00000260795ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1741428

+
In-frameENST00000260795ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1732898

+
In-frameENST00000260795ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1732899

+
In-frameENST00000260795ENST00000313288FGFR3chr4

1808650

+TACC3chr4

1737483

+
In-frameENST00000260795ENST00000313288FGFR3chr4

1808651

+TACC3chr4

1737484

+
In-frameENST00000260795ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1746245

+
In-frameENST00000340107ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1741429

+
In-frameENST00000340107ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1737458

+
In-frameENST00000340107ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1737457

+
In-frameENST00000340107ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1741428

+
In-frameENST00000340107ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1739324

+
In-frameENST00000340107ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1739325

+
In-frameENST00000340107ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1741428

+
In-frameENST00000340107ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1732898

+
In-frameENST00000340107ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1732899

+
In-frameENST00000340107ENST00000313288FGFR3chr4

1808650

+TACC3chr4

1737483

+
In-frameENST00000340107ENST00000313288FGFR3chr4

1808651

+TACC3chr4

1737484

+
In-frameENST00000340107ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1746245

+
In-frameENST00000352904ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1741429

+
In-frameENST00000352904ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1737458

+
In-frameENST00000352904ENST00000313288FGFR3chr4

1808947

+TACC3chr4

1742621

+
In-frameENST00000352904ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1737457

+
In-frameENST00000352904ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1741428

+
In-frameENST00000352904ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1739324

+
In-frameENST00000352904ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1739325

+
In-frameENST00000352904ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1741428

+
In-frameENST00000352904ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1732898

+
In-frameENST00000352904ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1732899

+
In-frameENST00000352904ENST00000313288FGFR3chr4

1808650

+TACC3chr4

1737483

+
In-frameENST00000352904ENST00000313288FGFR3chr4

1808651

+TACC3chr4

1737484

+
In-frameENST00000352904ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1746245

+
In-frameENST00000412135ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1741429

+
In-frameENST00000412135ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1737458

+
In-frameENST00000412135ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1737457

+
In-frameENST00000412135ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1741428

+
In-frameENST00000412135ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1739324

+
In-frameENST00000412135ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1739325

+
In-frameENST00000412135ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1741428

+
In-frameENST00000412135ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1732898

+
In-frameENST00000412135ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1732899

+
In-frameENST00000412135ENST00000313288FGFR3chr4

1808650

+TACC3chr4

1737483

+
In-frameENST00000412135ENST00000313288FGFR3chr4

1808651

+TACC3chr4

1737484

+
In-frameENST00000412135ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1746245

+
In-frameENST00000440486ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1741429

+
In-frameENST00000440486ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1737458

+
In-frameENST00000440486ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1737457

+
In-frameENST00000440486ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1741428

+
In-frameENST00000440486ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1739324

+
In-frameENST00000440486ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1739325

+
In-frameENST00000440486ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1741428

+
In-frameENST00000440486ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1732898

+
In-frameENST00000440486ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1732899

+
In-frameENST00000440486ENST00000313288FGFR3chr4

1808650

+TACC3chr4

1737483

+
In-frameENST00000440486ENST00000313288FGFR3chr4

1808651

+TACC3chr4

1737484

+
In-frameENST00000440486ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1746245

+
In-frameENST00000481110ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1737000

+
In-frameENST00000481110ENST00000313288FGFR3chr4

1808410

+TACC3chr4

1737457

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1741429

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1737458

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1795770

+TACC3chr4

1746245

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1808947

+TACC3chr4

1742621

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1737457

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1741428

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1739324

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1739325

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1807798

+TACC3chr4

1729971

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1741428

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1808660

+TACC3chr4

1732898

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1732899

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1801539

+TACC3chr4

1746245

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1801250

+TACC3chr4

1729435

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1737000

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1808650

+TACC3chr4

1737483

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1808651

+TACC3chr4

1737484

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1808661

+TACC3chr4

1746245

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1808410

+TACC3chr4

1737457

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1810599

+TACC3chr4

1737457

+
intron-3CDSENST00000474521ENST00000313288FGFR3chr4

1810599

+TACC3chr4

1741428

+
intron-3CDSENST00000481110ENST00000313288FGFR3chr4

1810599

+TACC3chr4

1737457

+
intron-3CDSENST00000481110ENST00000313288FGFR3chr4

1810599

+TACC3chr4

1741428

+
intron-intronENST00000260795ENST00000313288FGFR3chr4

1808738

+TACC3chr4

1734261

+
intron-intronENST00000340107ENST00000313288FGFR3chr4

1808738

+TACC3chr4

1734261

+
intron-intronENST00000352904ENST00000313288FGFR3chr4

1808738

+TACC3chr4

1734261

+
intron-intronENST00000412135ENST00000313288FGFR3chr4

1808738

+TACC3chr4

1734261

+
intron-intronENST00000440486ENST00000313288FGFR3chr4

1808738

+TACC3chr4

1734261

+
intron-intronENST00000474521ENST00000313288FGFR3chr4

1808925

+TACC3chr4

1741371

+
intron-intronENST00000474521ENST00000313288FGFR3chr4

1808922

+TACC3chr4

1741371

+
intron-intronENST00000474521ENST00000313288FGFR3chr4

1808738

+TACC3chr4

1734261

+
intron-intronENST00000481110ENST00000313288FGFR3chr4

1808738

+TACC3chr4

1734261

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

Top

Fusion Genomic Features for FGFR3-TACC3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
FGFR3chr41808661+TACC3chr41732898+0.0036471960.9963528
FGFR3chr41808661+TACC3chr41732898+0.0036471960.9963528
FGFR3chr41808661+TACC3chr41741428+0.0004786510.9995214
FGFR3chr41808661+TACC3chr41741428+0.0004786510.9995214
FGFR3chr41808661+TACC3chr41741428+0.0004786510.9995214
FGFR3chr41808661+TACC3chr41741428+0.0004786510.9995214
FGFR3chr41808661+TACC3chr41741428+0.0004786510.9995214
FGFR3chr41801250+TACC3chr41729434+8.26E-050.9999174
FGFR3chr41808661+TACC3chr41736999+1.41E-050.99998593
FGFR3chr41808661+TACC3chr41736999+1.41E-050.99998593
FGFR3chr41808661+TACC3chr41739324+9.75E-060.9999902
FGFR3chr41808661+TACC3chr41739324+9.75E-060.9999902
FGFR3chr41808661+TACC3chr41739324+9.75E-060.9999902
FGFR3chr41801539+TACC3chr41746244+8.51E-060.99999154
FGFR3chr41795770+TACC3chr41746244+8.73E-070.99999917
FGFR3chr41795770+TACC3chr41746244+8.73E-070.99999917
FGFR3chr41808661+TACC3chr41737457+5.41E-081
FGFR3chr41808661+TACC3chr41746244+1.64E-081
FGFR3chr41808661+TACC3chr41737457+5.41E-081
FGFR3chr41808661+TACC3chr41746244+1.64E-081
FGFR3chr41808661+TACC3chr41732898+0.0036471960.9963528
FGFR3chr41808661+TACC3chr41732898+0.0036471960.9963528
FGFR3chr41808661+TACC3chr41741428+0.0004786510.9995214
FGFR3chr41808661+TACC3chr41741428+0.0004786510.9995214
FGFR3chr41808661+TACC3chr41741428+0.0004786510.9995214
FGFR3chr41808661+TACC3chr41741428+0.0004786510.9995214
FGFR3chr41808661+TACC3chr41741428+0.0004786510.9995214
FGFR3chr41801250+TACC3chr41729434+8.26E-050.9999174
FGFR3chr41808661+TACC3chr41736999+1.41E-050.99998593
FGFR3chr41808661+TACC3chr41736999+1.41E-050.99998593
FGFR3chr41808661+TACC3chr41739324+9.75E-060.9999902
FGFR3chr41808661+TACC3chr41739324+9.75E-060.9999902
FGFR3chr41808661+TACC3chr41739324+9.75E-060.9999902
FGFR3chr41801539+TACC3chr41746244+8.51E-060.99999154
FGFR3chr41795770+TACC3chr41746244+8.73E-070.99999917
FGFR3chr41795770+TACC3chr41746244+8.73E-070.99999917
FGFR3chr41808661+TACC3chr41737457+5.41E-081
FGFR3chr41808661+TACC3chr41746244+1.64E-081
FGFR3chr41808661+TACC3chr41737457+5.41E-081
FGFR3chr41808661+TACC3chr41746244+1.64E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for FGFR3-TACC3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:1808661/chr4:1741429)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FGFR3

P22607

TACC3

Q9Y6A5

FUNCTION: Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts. Promotes apoptosis in chondrocytes, but can also promote cancer cell proliferation. Required for normal development of the inner ear. Phosphorylates PLCG1, CBL and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Plays a role in the regulation of vitamin D metabolism. Mutations that lead to constitutive kinase activation or impair normal FGFR3 maturation, internalization and degradation lead to aberrant signaling. Over-expressed or constitutively activated FGFR3 promotes activation of PTPN11/SHP2, STAT1, STAT5A and STAT5B. Secreted isoform 3 retains its capacity to bind FGF1 and FGF2 and hence may interfere with FGF signaling. {ECO:0000269|PubMed:10611230, ECO:0000269|PubMed:11294897, ECO:0000269|PubMed:11703096, ECO:0000269|PubMed:14534538, ECO:0000269|PubMed:16410555, ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:17145761, ECO:0000269|PubMed:17311277, ECO:0000269|PubMed:17509076, ECO:0000269|PubMed:17561467, ECO:0000269|PubMed:19088846, ECO:0000269|PubMed:19286672, ECO:0000269|PubMed:8663044}.FUNCTION: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:21297582, PubMed:23532825). May be involved in the control of cell growth and differentiation. May contribute to cancer (PubMed:14767476). {ECO:0000250|UniProtKB:Q9JJ11, ECO:0000269|PubMed:14767476, ECO:0000269|PubMed:21297582, ECO:0000269|PubMed:23532825}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

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* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFGFR3chr4:1808660chr4:1732898ENST00000260795+1617151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808660chr4:1732898ENST00000260795+161724_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808660chr4:1732898ENST00000260795+1617253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808660chr4:1732898ENST00000260795+1617472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808660chr4:1732898ENST00000340107+1718151_244760809.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808660chr4:1732898ENST00000340107+171824_126760809.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808660chr4:1732898ENST00000340107+1718253_355760809.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808660chr4:1732898ENST00000340107+1718472_761760809.0DomainProtein kinase
HgeneFGFR3chr4:1808660chr4:1732898ENST00000352904+1415151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808660chr4:1732898ENST00000352904+141524_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808660chr4:1732898ENST00000352904+1415253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808660chr4:1732898ENST00000412135+1516151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808660chr4:1732898ENST00000412135+151624_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808660chr4:1732898ENST00000412135+1516253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808660chr4:1732898ENST00000440486+1718151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808660chr4:1732898ENST00000440486+171824_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808660chr4:1732898ENST00000440486+1718253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808660chr4:1732898ENST00000440486+1718472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808660chr4:1737457ENST00000260795+1617151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808660chr4:1737457ENST00000260795+161724_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808660chr4:1737457ENST00000260795+1617253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808660chr4:1737457ENST00000260795+1617472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808660chr4:1737457ENST00000340107+1718151_244760809.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808660chr4:1737457ENST00000340107+171824_126760809.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808660chr4:1737457ENST00000340107+1718253_355760809.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808660chr4:1737457ENST00000340107+1718472_761760809.0DomainProtein kinase
HgeneFGFR3chr4:1808660chr4:1737457ENST00000352904+1415151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808660chr4:1737457ENST00000352904+141524_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808660chr4:1737457ENST00000352904+1415253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808660chr4:1737457ENST00000412135+1516151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808660chr4:1737457ENST00000412135+151624_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808660chr4:1737457ENST00000412135+1516253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808660chr4:1737457ENST00000440486+1718151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808660chr4:1737457ENST00000440486+171824_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808660chr4:1737457ENST00000440486+1718253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808660chr4:1737457ENST00000440486+1718472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808660chr4:1741428ENST00000260795+1617151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808660chr4:1741428ENST00000260795+161724_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808660chr4:1741428ENST00000260795+1617253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808660chr4:1741428ENST00000260795+1617472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808660chr4:1741428ENST00000340107+1718151_244760809.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808660chr4:1741428ENST00000340107+171824_126760809.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808660chr4:1741428ENST00000340107+1718253_355760809.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808660chr4:1741428ENST00000340107+1718472_761760809.0DomainProtein kinase
HgeneFGFR3chr4:1808660chr4:1741428ENST00000352904+1415151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808660chr4:1741428ENST00000352904+141524_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808660chr4:1741428ENST00000352904+1415253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808660chr4:1741428ENST00000412135+1516151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808660chr4:1741428ENST00000412135+151624_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808660chr4:1741428ENST00000412135+1516253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808660chr4:1741428ENST00000440486+1718151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808660chr4:1741428ENST00000440486+171824_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808660chr4:1741428ENST00000440486+1718253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808660chr4:1741428ENST00000440486+1718472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1732899ENST00000260795+1617151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1732899ENST00000260795+161724_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1732899ENST00000260795+1617253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1732899ENST00000260795+1617472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1732899ENST00000340107+1718151_244760809.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1732899ENST00000340107+171824_126760809.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1732899ENST00000340107+1718253_355760809.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1732899ENST00000340107+1718472_761760809.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1732899ENST00000352904+1415151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1732899ENST00000352904+141524_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1732899ENST00000352904+1415253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1732899ENST00000412135+1516151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1732899ENST00000412135+151624_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1732899ENST00000412135+1516253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1732899ENST00000440486+1718151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1732899ENST00000440486+171824_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1732899ENST00000440486+1718253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1732899ENST00000440486+1718472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1737000ENST00000260795+1617151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1737000ENST00000260795+161724_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1737000ENST00000260795+1617253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1737000ENST00000260795+1617472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1737000ENST00000340107+1718151_244760809.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1737000ENST00000340107+171824_126760809.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1737000ENST00000340107+1718253_355760809.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1737000ENST00000340107+1718472_761760809.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1737000ENST00000352904+1415151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1737000ENST00000352904+141524_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1737000ENST00000352904+1415253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1737000ENST00000412135+1516151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1737000ENST00000412135+151624_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1737000ENST00000412135+1516253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1737000ENST00000440486+1718151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1737000ENST00000440486+171824_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1737000ENST00000440486+1718253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1737000ENST00000440486+1718472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1737458ENST00000260795+1617151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1737458ENST00000260795+161724_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1737458ENST00000260795+1617253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1737458ENST00000260795+1617472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1737458ENST00000340107+1718151_244760809.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1737458ENST00000340107+171824_126760809.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1737458ENST00000340107+1718253_355760809.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1737458ENST00000340107+1718472_761760809.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1737458ENST00000352904+1415151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1737458ENST00000352904+141524_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1737458ENST00000352904+1415253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1737458ENST00000412135+1516151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1737458ENST00000412135+151624_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1737458ENST00000412135+1516253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1737458ENST00000440486+1718151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1737458ENST00000440486+171824_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1737458ENST00000440486+1718253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1737458ENST00000440486+1718472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1739324ENST00000260795+1617151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1739324ENST00000260795+161724_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1739324ENST00000260795+1617253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1739324ENST00000260795+1617472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1739324ENST00000340107+1718151_244760809.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1739324ENST00000340107+171824_126760809.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1739324ENST00000340107+1718253_355760809.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1739324ENST00000340107+1718472_761760809.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1739324ENST00000352904+1415151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1739324ENST00000352904+141524_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1739324ENST00000352904+1415253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1739324ENST00000412135+1516151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1739324ENST00000412135+151624_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1739324ENST00000412135+1516253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1739324ENST00000440486+1718151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1739324ENST00000440486+171824_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1739324ENST00000440486+1718253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1739324ENST00000440486+1718472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1739325ENST00000260795+1617151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1739325ENST00000260795+161724_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1739325ENST00000260795+1617253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1739325ENST00000260795+1617472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1739325ENST00000340107+1718151_244760809.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1739325ENST00000340107+171824_126760809.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1739325ENST00000340107+1718253_355760809.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1739325ENST00000340107+1718472_761760809.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1739325ENST00000352904+1415151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1739325ENST00000352904+141524_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1739325ENST00000352904+1415253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1739325ENST00000412135+1516151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1739325ENST00000412135+151624_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1739325ENST00000412135+1516253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1739325ENST00000440486+1718151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1739325ENST00000440486+171824_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1739325ENST00000440486+1718253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1739325ENST00000440486+1718472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1741428ENST00000260795+1617151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1741428ENST00000260795+161724_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1741428ENST00000260795+1617253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1741428ENST00000260795+1617472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1741428ENST00000340107+1718151_244760809.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1741428ENST00000340107+171824_126760809.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1741428ENST00000340107+1718253_355760809.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1741428ENST00000340107+1718472_761760809.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1741428ENST00000352904+1415151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1741428ENST00000352904+141524_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1741428ENST00000352904+1415253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1741428ENST00000412135+1516151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1741428ENST00000412135+151624_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1741428ENST00000412135+1516253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1741428ENST00000440486+1718151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1741428ENST00000440486+171824_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1741428ENST00000440486+1718253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1741428ENST00000440486+1718472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1741429ENST00000260795+1617151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1741429ENST00000260795+161724_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1741429ENST00000260795+1617253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1741429ENST00000260795+1617472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1741429ENST00000340107+1718151_244760809.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1741429ENST00000340107+171824_126760809.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1741429ENST00000340107+1718253_355760809.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1741429ENST00000340107+1718472_761760809.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1741429ENST00000352904+1415151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1741429ENST00000352904+141524_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1741429ENST00000352904+1415253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1741429ENST00000412135+1516151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1741429ENST00000412135+151624_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1741429ENST00000412135+1516253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1741429ENST00000440486+1718151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1741429ENST00000440486+171824_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1741429ENST00000440486+1718253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1741429ENST00000440486+1718472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1746245ENST00000260795+1617151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1746245ENST00000260795+161724_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1746245ENST00000260795+1617253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1746245ENST00000260795+1617472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1746245ENST00000340107+1718151_244760809.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1746245ENST00000340107+171824_126760809.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1746245ENST00000340107+1718253_355760809.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1746245ENST00000340107+1718472_761760809.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1746245ENST00000352904+1415151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1746245ENST00000352904+141524_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1746245ENST00000352904+1415253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1746245ENST00000412135+1516151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1746245ENST00000412135+151624_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1746245ENST00000412135+1516253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1746245ENST00000440486+1718151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808661chr4:1746245ENST00000440486+171824_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808661chr4:1746245ENST00000440486+1718253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808661chr4:1746245ENST00000440486+1718472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808663chr4:1741429ENST00000260795+1617151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808663chr4:1741429ENST00000260795+161724_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808663chr4:1741429ENST00000260795+1617253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808663chr4:1741429ENST00000260795+1617472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808663chr4:1741429ENST00000340107+1718151_244760809.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808663chr4:1741429ENST00000340107+171824_126760809.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808663chr4:1741429ENST00000340107+1718253_355760809.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808663chr4:1741429ENST00000340107+1718472_761760809.0DomainProtein kinase
HgeneFGFR3chr4:1808663chr4:1741429ENST00000352904+1415151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808663chr4:1741429ENST00000352904+141524_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808663chr4:1741429ENST00000352904+1415253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808663chr4:1741429ENST00000412135+1516151_244646695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808663chr4:1741429ENST00000412135+151624_126646695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808663chr4:1741429ENST00000412135+1516253_355646695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808663chr4:1741429ENST00000440486+1718151_244758807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808663chr4:1741429ENST00000440486+171824_126758807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808663chr4:1741429ENST00000440486+1718253_355758807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808663chr4:1741429ENST00000440486+1718472_761758807.0DomainProtein kinase
HgeneFGFR3chr4:1808660chr4:1732898ENST00000260795+1617478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808660chr4:1732898ENST00000340107+1718478_486760809.0Nucleotide bindingATP
HgeneFGFR3chr4:1808660chr4:1732898ENST00000352904+1415478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808660chr4:1732898ENST00000412135+1516478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808660chr4:1732898ENST00000440486+1718478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808660chr4:1737457ENST00000260795+1617478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808660chr4:1737457ENST00000340107+1718478_486760809.0Nucleotide bindingATP
HgeneFGFR3chr4:1808660chr4:1737457ENST00000352904+1415478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808660chr4:1737457ENST00000412135+1516478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808660chr4:1737457ENST00000440486+1718478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808660chr4:1741428ENST00000260795+1617478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808660chr4:1741428ENST00000340107+1718478_486760809.0Nucleotide bindingATP
HgeneFGFR3chr4:1808660chr4:1741428ENST00000352904+1415478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808660chr4:1741428ENST00000412135+1516478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808660chr4:1741428ENST00000440486+1718478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1732899ENST00000260795+1617478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1732899ENST00000340107+1718478_486760809.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1732899ENST00000352904+1415478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1732899ENST00000412135+1516478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1732899ENST00000440486+1718478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1737000ENST00000260795+1617478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1737000ENST00000340107+1718478_486760809.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1737000ENST00000352904+1415478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1737000ENST00000412135+1516478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1737000ENST00000440486+1718478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1737458ENST00000260795+1617478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1737458ENST00000340107+1718478_486760809.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1737458ENST00000352904+1415478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1737458ENST00000412135+1516478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1737458ENST00000440486+1718478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1739324ENST00000260795+1617478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1739324ENST00000340107+1718478_486760809.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1739324ENST00000352904+1415478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1739324ENST00000412135+1516478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1739324ENST00000440486+1718478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1739325ENST00000260795+1617478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1739325ENST00000340107+1718478_486760809.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1739325ENST00000352904+1415478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1739325ENST00000412135+1516478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1739325ENST00000440486+1718478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1741428ENST00000260795+1617478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1741428ENST00000340107+1718478_486760809.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1741428ENST00000352904+1415478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1741428ENST00000412135+1516478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1741428ENST00000440486+1718478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1741429ENST00000260795+1617478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1741429ENST00000340107+1718478_486760809.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1741429ENST00000352904+1415478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1741429ENST00000412135+1516478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1741429ENST00000440486+1718478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1746245ENST00000260795+1617478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1746245ENST00000340107+1718478_486760809.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1746245ENST00000352904+1415478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1746245ENST00000412135+1516478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808661chr4:1746245ENST00000440486+1718478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808663chr4:1741429ENST00000260795+1617478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808663chr4:1741429ENST00000340107+1718478_486760809.0Nucleotide bindingATP
HgeneFGFR3chr4:1808663chr4:1741429ENST00000352904+1415478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808663chr4:1741429ENST00000412135+1516478_486646695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808663chr4:1741429ENST00000440486+1718478_486758807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808660chr4:1732898ENST00000260795+161723_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808660chr4:1732898ENST00000340107+171823_375760809.0Topological domainExtracellular
HgeneFGFR3chr4:1808660chr4:1732898ENST00000352904+141523_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808660chr4:1732898ENST00000412135+151623_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808660chr4:1732898ENST00000440486+171823_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808660chr4:1737457ENST00000260795+161723_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808660chr4:1737457ENST00000340107+171823_375760809.0Topological domainExtracellular
HgeneFGFR3chr4:1808660chr4:1737457ENST00000352904+141523_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808660chr4:1737457ENST00000412135+151623_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808660chr4:1737457ENST00000440486+171823_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808660chr4:1741428ENST00000260795+161723_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808660chr4:1741428ENST00000340107+171823_375760809.0Topological domainExtracellular
HgeneFGFR3chr4:1808660chr4:1741428ENST00000352904+141523_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808660chr4:1741428ENST00000412135+151623_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808660chr4:1741428ENST00000440486+171823_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1732899ENST00000260795+161723_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1732899ENST00000340107+171823_375760809.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1732899ENST00000352904+141523_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1732899ENST00000412135+151623_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1732899ENST00000440486+171823_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1737000ENST00000260795+161723_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1737000ENST00000340107+171823_375760809.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1737000ENST00000352904+141523_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1737000ENST00000412135+151623_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1737000ENST00000440486+171823_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1737458ENST00000260795+161723_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1737458ENST00000340107+171823_375760809.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1737458ENST00000352904+141523_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1737458ENST00000412135+151623_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1737458ENST00000440486+171823_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1739324ENST00000260795+161723_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1739324ENST00000340107+171823_375760809.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1739324ENST00000352904+141523_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1739324ENST00000412135+151623_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1739324ENST00000440486+171823_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1739325ENST00000260795+161723_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1739325ENST00000340107+171823_375760809.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1739325ENST00000352904+141523_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1739325ENST00000412135+151623_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1739325ENST00000440486+171823_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1741428ENST00000260795+161723_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1741428ENST00000340107+171823_375760809.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1741428ENST00000352904+141523_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1741428ENST00000412135+151623_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1741428ENST00000440486+171823_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1741429ENST00000260795+161723_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1741429ENST00000340107+171823_375760809.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1741429ENST00000352904+141523_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1741429ENST00000412135+151623_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1741429ENST00000440486+171823_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1746245ENST00000260795+161723_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1746245ENST00000340107+171823_375760809.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1746245ENST00000352904+141523_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1746245ENST00000412135+151623_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808661chr4:1746245ENST00000440486+171823_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808663chr4:1741429ENST00000260795+161723_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808663chr4:1741429ENST00000340107+171823_375760809.0Topological domainExtracellular
HgeneFGFR3chr4:1808663chr4:1741429ENST00000352904+141523_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808663chr4:1741429ENST00000412135+151623_375646695.0Topological domainExtracellular
HgeneFGFR3chr4:1808663chr4:1741429ENST00000440486+171823_375758807.0Topological domainExtracellular
HgeneFGFR3chr4:1808660chr4:1732898ENST00000260795+1617376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808660chr4:1732898ENST00000340107+1718376_396760809.0TransmembraneHelical
HgeneFGFR3chr4:1808660chr4:1732898ENST00000352904+1415376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808660chr4:1732898ENST00000412135+1516376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808660chr4:1732898ENST00000440486+1718376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808660chr4:1737457ENST00000260795+1617376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808660chr4:1737457ENST00000340107+1718376_396760809.0TransmembraneHelical
HgeneFGFR3chr4:1808660chr4:1737457ENST00000352904+1415376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808660chr4:1737457ENST00000412135+1516376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808660chr4:1737457ENST00000440486+1718376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808660chr4:1741428ENST00000260795+1617376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808660chr4:1741428ENST00000340107+1718376_396760809.0TransmembraneHelical
HgeneFGFR3chr4:1808660chr4:1741428ENST00000352904+1415376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808660chr4:1741428ENST00000412135+1516376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808660chr4:1741428ENST00000440486+1718376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1732899ENST00000260795+1617376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1732899ENST00000340107+1718376_396760809.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1732899ENST00000352904+1415376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1732899ENST00000412135+1516376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1732899ENST00000440486+1718376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1737000ENST00000260795+1617376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1737000ENST00000340107+1718376_396760809.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1737000ENST00000352904+1415376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1737000ENST00000412135+1516376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1737000ENST00000440486+1718376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1737458ENST00000260795+1617376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1737458ENST00000340107+1718376_396760809.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1737458ENST00000352904+1415376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1737458ENST00000412135+1516376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1737458ENST00000440486+1718376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1739324ENST00000260795+1617376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1739324ENST00000340107+1718376_396760809.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1739324ENST00000352904+1415376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1739324ENST00000412135+1516376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1739324ENST00000440486+1718376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1739325ENST00000260795+1617376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1739325ENST00000340107+1718376_396760809.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1739325ENST00000352904+1415376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1739325ENST00000412135+1516376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1739325ENST00000440486+1718376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1741428ENST00000260795+1617376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1741428ENST00000340107+1718376_396760809.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1741428ENST00000352904+1415376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1741428ENST00000412135+1516376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1741428ENST00000440486+1718376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1741429ENST00000260795+1617376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1741429ENST00000340107+1718376_396760809.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1741429ENST00000352904+1415376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1741429ENST00000412135+1516376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1741429ENST00000440486+1718376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1746245ENST00000260795+1617376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1746245ENST00000340107+1718376_396760809.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1746245ENST00000352904+1415376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1746245ENST00000412135+1516376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808661chr4:1746245ENST00000440486+1718376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808663chr4:1741429ENST00000260795+1617376_396758807.0TransmembraneHelical
HgeneFGFR3chr4:1808663chr4:1741429ENST00000340107+1718376_396760809.0TransmembraneHelical
HgeneFGFR3chr4:1808663chr4:1741429ENST00000352904+1415376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808663chr4:1741429ENST00000412135+1516376_396646695.0TransmembraneHelical
HgeneFGFR3chr4:1808663chr4:1741429ENST00000440486+1718376_396758807.0TransmembraneHelical
TgeneTACC3chr4:1808650chr4:1737483ENST00000313288016637_8370839.0Coiled coilOntology_term=ECO:0000255
TgeneTACC3chr4:1808651chr4:1737484ENST00000313288016637_8370839.0Coiled coilOntology_term=ECO:0000255
TgeneTACC3chr4:1808660chr4:1732898ENST00000313288416637_837487839.0Coiled coilOntology_term=ECO:0000255
TgeneTACC3chr4:1808660chr4:1737457ENST00000313288616637_837548839.0Coiled coilOntology_term=ECO:0000255
TgeneTACC3chr4:1808661chr4:1732899ENST00000313288416637_837487839.0Coiled coilOntology_term=ECO:0000255
TgeneTACC3chr4:1808661chr4:1737000ENST00000313288516637_837530839.0Coiled coilOntology_term=ECO:0000255
TgeneTACC3chr4:1808661chr4:1737458ENST00000313288616637_837548839.0Coiled coilOntology_term=ECO:0000255
TgeneTACC3chr4:1808661chr4:1739324ENST00000313288816637_837612839.0Coiled coilOntology_term=ECO:0000255
TgeneTACC3chr4:1808661chr4:1739325ENST00000313288816637_837612839.0Coiled coilOntology_term=ECO:0000255
TgeneTACC3chr4:1808947chr4:1742621ENST00000313288016637_8370839.0Coiled coilOntology_term=ECO:0000255
TgeneTACC3chr4:1808650chr4:1737483ENST00000313288016155_1600839.0Compositional biasNote=Poly-Ser
TgeneTACC3chr4:1808651chr4:1737484ENST00000313288016155_1600839.0Compositional biasNote=Poly-Ser
TgeneTACC3chr4:1808947chr4:1742621ENST00000313288016155_1600839.0Compositional biasNote=Poly-Ser
TgeneTACC3chr4:1808650chr4:1737483ENST00000313288016522_5770839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808650chr4:1737483ENST00000313288016594_8380839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808651chr4:1737484ENST00000313288016522_5770839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808651chr4:1737484ENST00000313288016594_8380839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808660chr4:1732898ENST00000313288416522_577487839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808660chr4:1732898ENST00000313288416594_838487839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808660chr4:1737457ENST00000313288616594_838548839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808661chr4:1732899ENST00000313288416522_577487839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808661chr4:1732899ENST00000313288416594_838487839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808661chr4:1737000ENST00000313288516594_838530839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808661chr4:1737458ENST00000313288616594_838548839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808947chr4:1742621ENST00000313288016522_5770839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808947chr4:1742621ENST00000313288016594_8380839.0RegionNecessary but not sufficient for spindle localization

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFGFR3chr4:1808650chr4:1737483ENST00000260795+117151_2440807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808650chr4:1737483ENST00000260795+11724_1260807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808650chr4:1737483ENST00000260795+117253_3550807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808650chr4:1737483ENST00000260795+117472_7610807.0DomainProtein kinase
HgeneFGFR3chr4:1808650chr4:1737483ENST00000340107+118151_2440809.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808650chr4:1737483ENST00000340107+11824_1260809.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808650chr4:1737483ENST00000340107+118253_3550809.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808650chr4:1737483ENST00000340107+118472_7610809.0DomainProtein kinase
HgeneFGFR3chr4:1808650chr4:1737483ENST00000352904+115151_2440695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808650chr4:1737483ENST00000352904+11524_1260695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808650chr4:1737483ENST00000352904+115253_3550695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808650chr4:1737483ENST00000352904+115472_7610695.0DomainProtein kinase
HgeneFGFR3chr4:1808650chr4:1737483ENST00000412135+116151_2440695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808650chr4:1737483ENST00000412135+11624_1260695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808650chr4:1737483ENST00000412135+116253_3550695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808650chr4:1737483ENST00000412135+116472_7610695.0DomainProtein kinase
HgeneFGFR3chr4:1808650chr4:1737483ENST00000440486+118151_2440807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808650chr4:1737483ENST00000440486+11824_1260807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808650chr4:1737483ENST00000440486+118253_3550807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808650chr4:1737483ENST00000440486+118472_7610807.0DomainProtein kinase
HgeneFGFR3chr4:1808651chr4:1737484ENST00000260795+117151_2440807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808651chr4:1737484ENST00000260795+11724_1260807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808651chr4:1737484ENST00000260795+117253_3550807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808651chr4:1737484ENST00000260795+117472_7610807.0DomainProtein kinase
HgeneFGFR3chr4:1808651chr4:1737484ENST00000340107+118151_2440809.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808651chr4:1737484ENST00000340107+11824_1260809.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808651chr4:1737484ENST00000340107+118253_3550809.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808651chr4:1737484ENST00000340107+118472_7610809.0DomainProtein kinase
HgeneFGFR3chr4:1808651chr4:1737484ENST00000352904+115151_2440695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808651chr4:1737484ENST00000352904+11524_1260695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808651chr4:1737484ENST00000352904+115253_3550695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808651chr4:1737484ENST00000352904+115472_7610695.0DomainProtein kinase
HgeneFGFR3chr4:1808651chr4:1737484ENST00000412135+116151_2440695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808651chr4:1737484ENST00000412135+11624_1260695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808651chr4:1737484ENST00000412135+116253_3550695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808651chr4:1737484ENST00000412135+116472_7610695.0DomainProtein kinase
HgeneFGFR3chr4:1808651chr4:1737484ENST00000440486+118151_2440807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808651chr4:1737484ENST00000440486+11824_1260807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808651chr4:1737484ENST00000440486+118253_3550807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808651chr4:1737484ENST00000440486+118472_7610807.0DomainProtein kinase
HgeneFGFR3chr4:1808660chr4:1732898ENST00000352904+1415472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808660chr4:1732898ENST00000412135+1516472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808660chr4:1737457ENST00000352904+1415472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808660chr4:1737457ENST00000412135+1516472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808660chr4:1741428ENST00000352904+1415472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808660chr4:1741428ENST00000412135+1516472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1732899ENST00000352904+1415472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1732899ENST00000412135+1516472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1737000ENST00000352904+1415472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1737000ENST00000412135+1516472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1737458ENST00000352904+1415472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1737458ENST00000412135+1516472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1739324ENST00000352904+1415472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1739324ENST00000412135+1516472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1739325ENST00000352904+1415472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1739325ENST00000412135+1516472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1741428ENST00000352904+1415472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1741428ENST00000412135+1516472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1741429ENST00000352904+1415472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1741429ENST00000412135+1516472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1746245ENST00000352904+1415472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808661chr4:1746245ENST00000412135+1516472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808663chr4:1741429ENST00000352904+1415472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808663chr4:1741429ENST00000412135+1516472_761646695.0DomainProtein kinase
HgeneFGFR3chr4:1808947chr4:1742621ENST00000260795+117151_2440807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808947chr4:1742621ENST00000260795+11724_1260807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808947chr4:1742621ENST00000260795+117253_3550807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808947chr4:1742621ENST00000260795+117472_7610807.0DomainProtein kinase
HgeneFGFR3chr4:1808947chr4:1742621ENST00000340107+118151_2440809.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808947chr4:1742621ENST00000340107+11824_1260809.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808947chr4:1742621ENST00000340107+118253_3550809.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808947chr4:1742621ENST00000340107+118472_7610809.0DomainProtein kinase
HgeneFGFR3chr4:1808947chr4:1742621ENST00000352904+115151_2440695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808947chr4:1742621ENST00000352904+11524_1260695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808947chr4:1742621ENST00000352904+115253_3550695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808947chr4:1742621ENST00000352904+115472_7610695.0DomainProtein kinase
HgeneFGFR3chr4:1808947chr4:1742621ENST00000412135+116151_2440695.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808947chr4:1742621ENST00000412135+11624_1260695.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808947chr4:1742621ENST00000412135+116253_3550695.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808947chr4:1742621ENST00000412135+116472_7610695.0DomainProtein kinase
HgeneFGFR3chr4:1808947chr4:1742621ENST00000440486+118151_2440807.0DomainNote=Ig-like C2-type 2
HgeneFGFR3chr4:1808947chr4:1742621ENST00000440486+11824_1260807.0DomainNote=Ig-like C2-type 1
HgeneFGFR3chr4:1808947chr4:1742621ENST00000440486+118253_3550807.0DomainNote=Ig-like C2-type 3
HgeneFGFR3chr4:1808947chr4:1742621ENST00000440486+118472_7610807.0DomainProtein kinase
HgeneFGFR3chr4:1808650chr4:1737483ENST00000260795+117478_4860807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808650chr4:1737483ENST00000340107+118478_4860809.0Nucleotide bindingATP
HgeneFGFR3chr4:1808650chr4:1737483ENST00000352904+115478_4860695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808650chr4:1737483ENST00000412135+116478_4860695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808650chr4:1737483ENST00000440486+118478_4860807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808651chr4:1737484ENST00000260795+117478_4860807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808651chr4:1737484ENST00000340107+118478_4860809.0Nucleotide bindingATP
HgeneFGFR3chr4:1808651chr4:1737484ENST00000352904+115478_4860695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808651chr4:1737484ENST00000412135+116478_4860695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808651chr4:1737484ENST00000440486+118478_4860807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808947chr4:1742621ENST00000260795+117478_4860807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808947chr4:1742621ENST00000340107+118478_4860809.0Nucleotide bindingATP
HgeneFGFR3chr4:1808947chr4:1742621ENST00000352904+115478_4860695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808947chr4:1742621ENST00000412135+116478_4860695.0Nucleotide bindingATP
HgeneFGFR3chr4:1808947chr4:1742621ENST00000440486+118478_4860807.0Nucleotide bindingATP
HgeneFGFR3chr4:1808650chr4:1737483ENST00000260795+11723_3750807.0Topological domainExtracellular
HgeneFGFR3chr4:1808650chr4:1737483ENST00000260795+117397_8060807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808650chr4:1737483ENST00000340107+11823_3750809.0Topological domainExtracellular
HgeneFGFR3chr4:1808650chr4:1737483ENST00000340107+118397_8060809.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808650chr4:1737483ENST00000352904+11523_3750695.0Topological domainExtracellular
HgeneFGFR3chr4:1808650chr4:1737483ENST00000352904+115397_8060695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808650chr4:1737483ENST00000412135+11623_3750695.0Topological domainExtracellular
HgeneFGFR3chr4:1808650chr4:1737483ENST00000412135+116397_8060695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808650chr4:1737483ENST00000440486+11823_3750807.0Topological domainExtracellular
HgeneFGFR3chr4:1808650chr4:1737483ENST00000440486+118397_8060807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808651chr4:1737484ENST00000260795+11723_3750807.0Topological domainExtracellular
HgeneFGFR3chr4:1808651chr4:1737484ENST00000260795+117397_8060807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808651chr4:1737484ENST00000340107+11823_3750809.0Topological domainExtracellular
HgeneFGFR3chr4:1808651chr4:1737484ENST00000340107+118397_8060809.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808651chr4:1737484ENST00000352904+11523_3750695.0Topological domainExtracellular
HgeneFGFR3chr4:1808651chr4:1737484ENST00000352904+115397_8060695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808651chr4:1737484ENST00000412135+11623_3750695.0Topological domainExtracellular
HgeneFGFR3chr4:1808651chr4:1737484ENST00000412135+116397_8060695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808651chr4:1737484ENST00000440486+11823_3750807.0Topological domainExtracellular
HgeneFGFR3chr4:1808651chr4:1737484ENST00000440486+118397_8060807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808660chr4:1732898ENST00000260795+1617397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808660chr4:1732898ENST00000340107+1718397_806760809.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808660chr4:1732898ENST00000352904+1415397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808660chr4:1732898ENST00000412135+1516397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808660chr4:1732898ENST00000440486+1718397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808660chr4:1737457ENST00000260795+1617397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808660chr4:1737457ENST00000340107+1718397_806760809.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808660chr4:1737457ENST00000352904+1415397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808660chr4:1737457ENST00000412135+1516397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808660chr4:1737457ENST00000440486+1718397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808660chr4:1741428ENST00000260795+1617397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808660chr4:1741428ENST00000340107+1718397_806760809.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808660chr4:1741428ENST00000352904+1415397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808660chr4:1741428ENST00000412135+1516397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808660chr4:1741428ENST00000440486+1718397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1732899ENST00000260795+1617397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1732899ENST00000340107+1718397_806760809.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1732899ENST00000352904+1415397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1732899ENST00000412135+1516397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1732899ENST00000440486+1718397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1737000ENST00000260795+1617397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1737000ENST00000340107+1718397_806760809.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1737000ENST00000352904+1415397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1737000ENST00000412135+1516397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1737000ENST00000440486+1718397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1737458ENST00000260795+1617397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1737458ENST00000340107+1718397_806760809.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1737458ENST00000352904+1415397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1737458ENST00000412135+1516397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1737458ENST00000440486+1718397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1739324ENST00000260795+1617397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1739324ENST00000340107+1718397_806760809.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1739324ENST00000352904+1415397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1739324ENST00000412135+1516397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1739324ENST00000440486+1718397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1739325ENST00000260795+1617397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1739325ENST00000340107+1718397_806760809.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1739325ENST00000352904+1415397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1739325ENST00000412135+1516397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1739325ENST00000440486+1718397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1741428ENST00000260795+1617397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1741428ENST00000340107+1718397_806760809.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1741428ENST00000352904+1415397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1741428ENST00000412135+1516397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1741428ENST00000440486+1718397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1741429ENST00000260795+1617397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1741429ENST00000340107+1718397_806760809.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1741429ENST00000352904+1415397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1741429ENST00000412135+1516397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1741429ENST00000440486+1718397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1746245ENST00000260795+1617397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1746245ENST00000340107+1718397_806760809.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1746245ENST00000352904+1415397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1746245ENST00000412135+1516397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808661chr4:1746245ENST00000440486+1718397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808663chr4:1741429ENST00000260795+1617397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808663chr4:1741429ENST00000340107+1718397_806760809.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808663chr4:1741429ENST00000352904+1415397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808663chr4:1741429ENST00000412135+1516397_806646695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808663chr4:1741429ENST00000440486+1718397_806758807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808947chr4:1742621ENST00000260795+11723_3750807.0Topological domainExtracellular
HgeneFGFR3chr4:1808947chr4:1742621ENST00000260795+117397_8060807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808947chr4:1742621ENST00000340107+11823_3750809.0Topological domainExtracellular
HgeneFGFR3chr4:1808947chr4:1742621ENST00000340107+118397_8060809.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808947chr4:1742621ENST00000352904+11523_3750695.0Topological domainExtracellular
HgeneFGFR3chr4:1808947chr4:1742621ENST00000352904+115397_8060695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808947chr4:1742621ENST00000412135+11623_3750695.0Topological domainExtracellular
HgeneFGFR3chr4:1808947chr4:1742621ENST00000412135+116397_8060695.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808947chr4:1742621ENST00000440486+11823_3750807.0Topological domainExtracellular
HgeneFGFR3chr4:1808947chr4:1742621ENST00000440486+118397_8060807.0Topological domainCytoplasmic
HgeneFGFR3chr4:1808650chr4:1737483ENST00000260795+117376_3960807.0TransmembraneHelical
HgeneFGFR3chr4:1808650chr4:1737483ENST00000340107+118376_3960809.0TransmembraneHelical
HgeneFGFR3chr4:1808650chr4:1737483ENST00000352904+115376_3960695.0TransmembraneHelical
HgeneFGFR3chr4:1808650chr4:1737483ENST00000412135+116376_3960695.0TransmembraneHelical
HgeneFGFR3chr4:1808650chr4:1737483ENST00000440486+118376_3960807.0TransmembraneHelical
HgeneFGFR3chr4:1808651chr4:1737484ENST00000260795+117376_3960807.0TransmembraneHelical
HgeneFGFR3chr4:1808651chr4:1737484ENST00000340107+118376_3960809.0TransmembraneHelical
HgeneFGFR3chr4:1808651chr4:1737484ENST00000352904+115376_3960695.0TransmembraneHelical
HgeneFGFR3chr4:1808651chr4:1737484ENST00000412135+116376_3960695.0TransmembraneHelical
HgeneFGFR3chr4:1808651chr4:1737484ENST00000440486+118376_3960807.0TransmembraneHelical
HgeneFGFR3chr4:1808947chr4:1742621ENST00000260795+117376_3960807.0TransmembraneHelical
HgeneFGFR3chr4:1808947chr4:1742621ENST00000340107+118376_3960809.0TransmembraneHelical
HgeneFGFR3chr4:1808947chr4:1742621ENST00000352904+115376_3960695.0TransmembraneHelical
HgeneFGFR3chr4:1808947chr4:1742621ENST00000412135+116376_3960695.0TransmembraneHelical
HgeneFGFR3chr4:1808947chr4:1742621ENST00000440486+118376_3960807.0TransmembraneHelical
TgeneTACC3chr4:1808660chr4:1741428ENST00000313288916637_837647839.0Coiled coilOntology_term=ECO:0000255
TgeneTACC3chr4:1808661chr4:1741428ENST00000313288916637_837647839.0Coiled coilOntology_term=ECO:0000255
TgeneTACC3chr4:1808661chr4:1741429ENST00000313288916637_837647839.0Coiled coilOntology_term=ECO:0000255
TgeneTACC3chr4:1808661chr4:1746245ENST000003132881216637_837741839.0Coiled coilOntology_term=ECO:0000255
TgeneTACC3chr4:1808663chr4:1741429ENST00000313288916637_837647839.0Coiled coilOntology_term=ECO:0000255
TgeneTACC3chr4:1808660chr4:1732898ENST00000313288416155_160487839.0Compositional biasNote=Poly-Ser
TgeneTACC3chr4:1808660chr4:1737457ENST00000313288616155_160548839.0Compositional biasNote=Poly-Ser
TgeneTACC3chr4:1808660chr4:1741428ENST00000313288916155_160647839.0Compositional biasNote=Poly-Ser
TgeneTACC3chr4:1808661chr4:1732899ENST00000313288416155_160487839.0Compositional biasNote=Poly-Ser
TgeneTACC3chr4:1808661chr4:1737000ENST00000313288516155_160530839.0Compositional biasNote=Poly-Ser
TgeneTACC3chr4:1808661chr4:1737458ENST00000313288616155_160548839.0Compositional biasNote=Poly-Ser
TgeneTACC3chr4:1808661chr4:1739324ENST00000313288816155_160612839.0Compositional biasNote=Poly-Ser
TgeneTACC3chr4:1808661chr4:1739325ENST00000313288816155_160612839.0Compositional biasNote=Poly-Ser
TgeneTACC3chr4:1808661chr4:1741428ENST00000313288916155_160647839.0Compositional biasNote=Poly-Ser
TgeneTACC3chr4:1808661chr4:1741429ENST00000313288916155_160647839.0Compositional biasNote=Poly-Ser
TgeneTACC3chr4:1808661chr4:1746245ENST000003132881216155_160741839.0Compositional biasNote=Poly-Ser
TgeneTACC3chr4:1808663chr4:1741429ENST00000313288916155_160647839.0Compositional biasNote=Poly-Ser
TgeneTACC3chr4:1808660chr4:1737457ENST00000313288616522_577548839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808660chr4:1741428ENST00000313288916522_577647839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808660chr4:1741428ENST00000313288916594_838647839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808661chr4:1737000ENST00000313288516522_577530839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808661chr4:1737458ENST00000313288616522_577548839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808661chr4:1739324ENST00000313288816522_577612839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808661chr4:1739324ENST00000313288816594_838612839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808661chr4:1739325ENST00000313288816522_577612839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808661chr4:1739325ENST00000313288816594_838612839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808661chr4:1741428ENST00000313288916522_577647839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808661chr4:1741428ENST00000313288916594_838647839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808661chr4:1741429ENST00000313288916522_577647839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808661chr4:1741429ENST00000313288916594_838647839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808661chr4:1746245ENST000003132881216522_577741839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808661chr4:1746245ENST000003132881216594_838741839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808663chr4:1741429ENST00000313288916522_577647839.0RegionNecessary but not sufficient for spindle localization
TgeneTACC3chr4:1808663chr4:1741429ENST00000313288916594_838647839.0RegionNecessary but not sufficient for spindle localization


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Fusion Gene Sequence for FGFR3-TACC3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for FGFR3-TACC3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FGFR3-TACC3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneFGFR3P22607DB06589PazopanibInhibitorSmall moleculeApproved
HgeneFGFR3P22607DB06589PazopanibInhibitorSmall moleculeApproved
HgeneFGFR3P22607DB09079NintedanibInhibitorSmall moleculeApproved
HgeneFGFR3P22607DB09079NintedanibInhibitorSmall moleculeApproved
HgeneFGFR3P22607DB08901PonatinibInhibitorSmall moleculeApproved|Investigational
HgeneFGFR3P22607DB08901PonatinibInhibitorSmall moleculeApproved|Investigational
HgeneFGFR3P22607DB09078LenvatinibInhibitorSmall moleculeApproved|Investigational
HgeneFGFR3P22607DB09078LenvatinibInhibitorSmall moleculeApproved|Investigational
HgeneFGFR3P22607DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneFGFR3P22607DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneFGFR3P22607DB12147ErdafitinibInhibitorSmall moleculeApproved|Investigational
HgeneFGFR3P22607DB12147ErdafitinibInhibitorSmall moleculeApproved|Investigational
HgeneFGFR3P22607DB15102PemigatinibInhibitorSmall moleculeApproved|Investigational
HgeneFGFR3P22607DB15102PemigatinibInhibitorSmall moleculeApproved|Investigational
HgeneFGFR3P22607DB15685SelpercatinibInhibitorSmall moleculeApproved|Investigational
HgeneFGFR3P22607DB15685SelpercatinibInhibitorSmall moleculeApproved|Investigational

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Related Diseases for FGFR3-TACC3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneFGFR3C0001080Achondroplasia13CLINGEN;CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneFGFR3C0410529Hypochondroplasia (disorder)10CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneFGFR3C1864436Muenke Syndrome9CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneFGFR3C1868678THANATOPHORIC DYSPLASIA, TYPE I (disorder)9CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneFGFR3C2677099CROUZON SYNDROME WITH ACANTHOSIS NIGRICANS (disorder)7CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneFGFR3C0005684Malignant neoplasm of urinary bladder6CGI;CTD_human;UNIPROT
HgeneFGFR3C0005695Bladder Neoplasm4CGI;CTD_human
HgeneFGFR3C1300257Thanatophoric dysplasia, type 24CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneFGFR3C1864852CATSHL syndrome4CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneFGFR3C2674173Achondroplasia, Severe, With Developmental Delay And Acanthosis Nigricans3CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneFGFR3C0265269Lacrimoauriculodentodigital syndrome2CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneFGFR3C0007138Carcinoma, Transitional Cell1CTD_human
HgeneFGFR3C0008924Cleft upper lip1CTD_human
HgeneFGFR3C0008925Cleft Palate1CTD_human
HgeneFGFR3C0014544Epilepsy1GENOMICS_ENGLAND
HgeneFGFR3C0014547Epilepsies, Partial1GENOMICS_ENGLAND
HgeneFGFR3C0022603Seborrheic keratosis1UNIPROT
HgeneFGFR3C0026764Multiple Myeloma1CGI;CTD_human
HgeneFGFR3C0036631Seminoma1CTD_human
HgeneFGFR3C0039743Thanatophoric Dysplasia1CTD_human
HgeneFGFR3C0152423Congenital small ears1GENOMICS_ENGLAND
HgeneFGFR3C0206726gliosarcoma1ORPHANET
HgeneFGFR3C0221356Brachycephaly1ORPHANET
HgeneFGFR3C0265529Plagiocephaly1ORPHANET
HgeneFGFR3C0334082NEVUS, EPIDERMAL (disorder)1CTD_human;UNIPROT
HgeneFGFR3C0334588Giant Cell Glioblastoma1ORPHANET
HgeneFGFR3C0406803Syringocystadenoma Papilliferum1GENOMICS_ENGLAND
HgeneFGFR3C1336708Testicular Germ Cell Tumor1CTD_human;UNIPROT
HgeneFGFR3C1837218Cleft palate, isolated1CTD_human
HgeneFGFR3C4048328cervical cancer1CTD_human;UNIPROT
TgeneC0005684Malignant neoplasm of urinary bladder1CTD_human
TgeneC0005695Bladder Neoplasm1CTD_human
TgeneC0007138Carcinoma, Transitional Cell1CTD_human
TgeneC0206726gliosarcoma1ORPHANET
TgeneC0334588Giant Cell Glioblastoma1ORPHANET
TgeneC2239176Liver carcinoma1CTD_human