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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ABLIM3-AZU1 (FusionGDB2 ID:HG22885TG566)

Fusion Gene Summary for ABLIM3-AZU1

check button Fusion gene summary
Fusion gene informationFusion gene name: ABLIM3-AZU1
Fusion gene ID: hg22885tg566
HgeneTgene
Gene symbol

ABLIM3

AZU1

Gene ID

22885

566

Gene nameactin binding LIM protein family member 3azurocidin 1
SynonymsHMFN1661AZAMP|AZU|CAP37|HBP|HUMAZUR|NAZC|hHBP
Cytomap('ABLIM3')('AZU1')

5q32

19p13.3

Type of geneprotein-codingprotein-coding
Descriptionactin-binding LIM protein 3abLIM-3azurocidincationic antimicrobial protein 37cationic antimicrobial protein CAP37heparin-binding proteinneutrophil azurocidin
Modification date2020031320200313
UniProtAcc.

P20160

Ensembl transtripts involved in fusion geneENST00000309868, ENST00000326685, 
ENST00000356541, ENST00000504238, 
ENST00000506113, ENST00000508983, 
ENST00000517451, ENST00000519549, 
Fusion gene scores* DoF score4 X 4 X 3=483 X 2 X 3=18
# samples 44
** MAII scorelog2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/18*10)=1.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: ABLIM3 [Title/Abstract] AND AZU1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointABLIM3(148627492)-AZU1(828230), # samples:1
Anticipated loss of major functional domain due to fusion event.ABLIM3-AZU1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABLIM3-AZU1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABLIM3-AZU1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ABLIM3-AZU1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneAZU1

GO:0006508

proteolysis

21550830

TgeneAZU1

GO:0008347

glial cell migration

12465046

TgeneAZU1

GO:0010800

positive regulation of peptidyl-threonine phosphorylation

24008408

TgeneAZU1

GO:0042535

positive regulation of tumor necrosis factor biosynthetic process

12465046

TgeneAZU1

GO:0045785

positive regulation of cell adhesion

12826073|15879141

TgeneAZU1

GO:0045860

positive regulation of protein kinase activity

24008408

TgeneAZU1

GO:0050725

positive regulation of interleukin-1 beta biosynthetic process

12465046

TgeneAZU1

GO:0050754

positive regulation of fractalkine biosynthetic process

12465046

TgeneAZU1

GO:0050766

positive regulation of phagocytosis

12465046

TgeneAZU1

GO:0070944

neutrophil mediated killing of bacterium

2312733


check buttonFusion gene breakpoints across ABLIM3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across AZU1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-C8-A12X-01AABLIM3chr5

148627492

+AZU1chr19

828230

+


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Fusion Gene ORF analysis for ABLIM3-AZU1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000309868ENST00000233997ABLIM3chr5

148627492

+AZU1chr19

828230

+
In-frameENST00000326685ENST00000233997ABLIM3chr5

148627492

+AZU1chr19

828230

+
In-frameENST00000356541ENST00000233997ABLIM3chr5

148627492

+AZU1chr19

828230

+
In-frameENST00000504238ENST00000233997ABLIM3chr5

148627492

+AZU1chr19

828230

+
In-frameENST00000506113ENST00000233997ABLIM3chr5

148627492

+AZU1chr19

828230

+
In-frameENST00000508983ENST00000233997ABLIM3chr5

148627492

+AZU1chr19

828230

+
In-frameENST00000517451ENST00000233997ABLIM3chr5

148627492

+AZU1chr19

828230

+
intron-3CDSENST00000519549ENST00000233997ABLIM3chr5

148627492

+AZU1chr19

828230

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000326685ABLIM3chr5148627492+ENST00000233997AZU1chr19828230+251116732592370703
ENST00000356541ABLIM3chr5148627492+ENST00000233997AZU1chr19828230+245516172512314687
ENST00000309868ABLIM3chr5148627492+ENST00000233997AZU1chr19828230+277619382392635798
ENST00000506113ABLIM3chr5148627492+ENST00000233997AZU1chr19828230+301921814822878798
ENST00000504238ABLIM3chr5148627492+ENST00000233997AZU1chr19828230+247916412752338687
ENST00000508983ABLIM3chr5148627492+ENST00000233997AZU1chr19828230+24871649492346765
ENST00000517451ABLIM3chr5148627492+ENST00000233997AZU1chr19828230+2719188123591292355

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000326685ENST00000233997ABLIM3chr5148627492+AZU1chr19828230+0.024463990.97553605
ENST00000356541ENST00000233997ABLIM3chr5148627492+AZU1chr19828230+0.0292645340.9707355
ENST00000309868ENST00000233997ABLIM3chr5148627492+AZU1chr19828230+0.0130139170.9869861
ENST00000506113ENST00000233997ABLIM3chr5148627492+AZU1chr19828230+0.009691950.990308
ENST00000504238ENST00000233997ABLIM3chr5148627492+AZU1chr19828230+0.0243389290.97566104
ENST00000508983ENST00000233997ABLIM3chr5148627492+AZU1chr19828230+0.0131399250.9868601
ENST00000517451ENST00000233997ABLIM3chr5148627492+AZU1chr19828230+0.350118340.64988166

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Fusion Genomic Features for ABLIM3-AZU1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ABLIM3chr5148627492+AZU1chr19828229+0.0217197520.9782802
ABLIM3chr5148627492+AZU1chr19828229+0.0217197520.9782802

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ABLIM3-AZU1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:148627492/chr19:828230)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AZU1

P20160

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G. {ECO:0000269|PubMed:1399008, ECO:0000269|PubMed:1937776, ECO:0000269|PubMed:2312733}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABLIM3chr5:148627492chr19:828230ENST00000309868+1824149_208566684.0DomainLIM zinc-binding 3
HgeneABLIM3chr5:148627492chr19:828230ENST00000309868+1824208_268566684.0DomainLIM zinc-binding 4
HgeneABLIM3chr5:148627492chr19:828230ENST00000309868+182421_80566684.0DomainLIM zinc-binding 1
HgeneABLIM3chr5:148627492chr19:828230ENST00000309868+182480_140566684.0DomainLIM zinc-binding 2
HgeneABLIM3chr5:148627492chr19:828230ENST00000326685+1521149_208471589.0DomainLIM zinc-binding 3
HgeneABLIM3chr5:148627492chr19:828230ENST00000326685+1521208_268471589.0DomainLIM zinc-binding 4
HgeneABLIM3chr5:148627492chr19:828230ENST00000326685+152121_80471589.0DomainLIM zinc-binding 1
HgeneABLIM3chr5:148627492chr19:828230ENST00000326685+152180_140471589.0DomainLIM zinc-binding 2
HgeneABLIM3chr5:148627492chr19:828230ENST00000356541+1420149_208455545.0DomainLIM zinc-binding 3
HgeneABLIM3chr5:148627492chr19:828230ENST00000356541+1420208_268455545.0DomainLIM zinc-binding 4
HgeneABLIM3chr5:148627492chr19:828230ENST00000356541+142021_80455545.0DomainLIM zinc-binding 1
HgeneABLIM3chr5:148627492chr19:828230ENST00000356541+142080_140455545.0DomainLIM zinc-binding 2
HgeneABLIM3chr5:148627492chr19:828230ENST00000504238+1319149_208455545.0DomainLIM zinc-binding 3
HgeneABLIM3chr5:148627492chr19:828230ENST00000504238+1319208_268455545.0DomainLIM zinc-binding 4
HgeneABLIM3chr5:148627492chr19:828230ENST00000504238+131921_80455545.0DomainLIM zinc-binding 1
HgeneABLIM3chr5:148627492chr19:828230ENST00000504238+131980_140455545.0DomainLIM zinc-binding 2
HgeneABLIM3chr5:148627492chr19:828230ENST00000506113+1723149_208566684.0DomainLIM zinc-binding 3
HgeneABLIM3chr5:148627492chr19:828230ENST00000506113+1723208_268566684.0DomainLIM zinc-binding 4
HgeneABLIM3chr5:148627492chr19:828230ENST00000506113+172321_80566684.0DomainLIM zinc-binding 1
HgeneABLIM3chr5:148627492chr19:828230ENST00000506113+172380_140566684.0DomainLIM zinc-binding 2
HgeneABLIM3chr5:148627492chr19:828230ENST00000508983+1622149_208533651.0DomainLIM zinc-binding 3
HgeneABLIM3chr5:148627492chr19:828230ENST00000508983+1622208_268533651.0DomainLIM zinc-binding 4
HgeneABLIM3chr5:148627492chr19:828230ENST00000508983+162221_80533651.0DomainLIM zinc-binding 1
HgeneABLIM3chr5:148627492chr19:828230ENST00000508983+162280_140533651.0DomainLIM zinc-binding 2
TgeneAZU1chr5:148627492chr19:828230ENST000002339970527_24419252.0DomainPeptidase S1
TgeneAZU1chr5:148627492chr19:828230ENST000002339970546_7019252.0RegionPossesses antibiotic activity

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABLIM3chr5:148627492chr19:828230ENST00000309868+1824615_683566684.0DomainHP
HgeneABLIM3chr5:148627492chr19:828230ENST00000326685+1521615_683471589.0DomainHP
HgeneABLIM3chr5:148627492chr19:828230ENST00000356541+1420615_683455545.0DomainHP
HgeneABLIM3chr5:148627492chr19:828230ENST00000504238+1319615_683455545.0DomainHP
HgeneABLIM3chr5:148627492chr19:828230ENST00000506113+1723615_683566684.0DomainHP
HgeneABLIM3chr5:148627492chr19:828230ENST00000508983+1622615_683533651.0DomainHP
HgeneABLIM3chr5:148627492chr19:828230ENST00000517451+39149_20852170.0DomainLIM zinc-binding 3
HgeneABLIM3chr5:148627492chr19:828230ENST00000517451+39208_26852170.0DomainLIM zinc-binding 4
HgeneABLIM3chr5:148627492chr19:828230ENST00000517451+3921_8052170.0DomainLIM zinc-binding 1
HgeneABLIM3chr5:148627492chr19:828230ENST00000517451+39615_68352170.0DomainHP
HgeneABLIM3chr5:148627492chr19:828230ENST00000517451+3980_14052170.0DomainLIM zinc-binding 2


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Fusion Gene Sequence for ABLIM3-AZU1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>523_523_1_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000309868_AZU1_chr19_828230_ENST00000233997_length(transcript)=2776nt_BP=1938nt
CTGCCAACCCGCGAGCCCGCATCATGGATGTCGAGCTCCCCTATTTCGCATTGCTAGCCCTGGAATTCGAGACCCCAGACGAGGACCAGG
ATTCATGAAATCAGTCGCAGGGGCCGGGGCAGGGGCCTCTGGCTCCCGACACTGGCCGAGAGGTGATGAGTGAGGTTCGAAGAACGGAAG
ATTTAAAAAGCAGCCGGGGCCTCCGTATTGAATGAAAGACCCAGTGCAAAGACATCACCATGAACACTAGCATTCCTTATCAGCAGAATC
CTTACAATCCACGGGGCAGCTCCAATGTCATCCAGTGCTACCGCTGTGGAGACACCTGCAAAGGGGAAGTGGTCCGCGTGCACAACAACC
ACTTCCACATCAGATGCTTCACCTGTCAAGTATGTGGCTGTGGCCTGGCCCAGTCAGGCTTCTTCTTCAAGAACCAGGAGTACATCTGCA
CCCAGGACTACCAGCAACTCTATGGCACCCGCTGTGACAGCTGCCGGGACTTCATCACAGGCGAAGTCATCTCGGCCCTGGGCCGCACTT
ACCACCCCAAGTGCTTCGTGTGCAGCTTGTGCAGGAAGCCTTTCCCCATTGGAGACAAGGTGACCTTCAGCGGTAAAGAATGTGTGTGCC
AAACGTGCTCCCAGTCCATGGCCAGCAGTAAGCCCATCAAGATTCGTGGACCAAGCCACTGTGCCGGGTGCAAGGAGGAGATCAAGCACG
GCCAGTCACTCCTGGCTCTGGACAAGCAGTGGCACGTCAGCTGCTTCAAGTGCCAGACCTGCAGCGTCATCCTCACCGGGGAGTATATCA
GCAAGGATGGTGTTCCATACTGTGAGTCCGACTACCATGCCCAGTTTGGCATTAAATGTGAGACTTGTGACCGATACATCAGTGGCAGAG
TCTTGGAGGCAGGAGGGAAGCACTACCACCCAACCTGTGCCAGGTGTGTACGCTGCCACCAGATGTTCACCGAAGGAGAGGAAATGTACC
TCACAGGTTCCGAGGTTTGGCACCCCATCTGCAAACAGGCAGCCCGGGCAGAGAAGAAGTTAAAGCATAGACGGACATCTGAAACCTCCA
TCTCACCCCCTGGATCCAGCATTGGGTCACCCAACCGAGTCATCTGCGCTAAAGTGGATAATGAGATCCTTAATTACAAAGACCTGGCGG
CTCTCCCCAAGGTTAAGTCTATCTACGAGGTACAACGCCCCGACCTCATTTCCTATGAGCCTCATTCCAGATACATGTCCGACGAGATGC
TGGAGAGATGTGGCTATGGAGAGTCGCTGGGAACATTATCTCCCTACTCCCAGGACATCTACGAGAACCTGGACCTCCGGCAGAGACGGG
CCTCCAGCCCGGGGTACATAGACTCCCCCACCTACAGCCGGCAGGGCATGTCCCCCACCTTCTCCCGCTCACCTCACCACTACTACCGCT
CTGGGCCCGAGAGTGGCCGGAGCTCTCCATACCATAGCCAGTTAGATGTGAGGTCCTCCACTCCAACCTCTTACCAGGCTCCCAAGCACT
TTCACATCCCAGCTGGAGACAGTAACATCTACCGGAAACCCCCGATCTACAAACGGCATGGTGATTTGTCTACAGCAACCAAGAGCAAAA
CAAGTGAAGACATCAGCCAGACCTCCAAGTACAGTCCCATCTACTCGCCAGACCCCTACTATGCTTCGGAGTCTGAGTACTGGACCTACC
ATGGGTCCCCCAAAGTGCCCCGAGCCAGAAGGTTCTCGTCTGGAGGAGAGGAGGATGATTTTGACCGCAGCATGCACAAGCTCCAAAGTG
GAATTGGCCGGCTGATTCTGAAGGAAGAAATGAAGGCCCGGTCGAGCTCCTATGCAGATCCCTGGACCCCTCCCCGGAGCTCCACCAGCA
GCCGGGAAGCCCTGCACACAGCTGGCTATGAGATGTCCCTCAATGGCTGCTCCAGCCCCCTTTTGGACATCGTTGGCGGCCGGAAGGCGA
GGCCCCGCCAGTTCCCGTTCCTGGCCTCCATTCAGAATCAAGGCAGGCACTTCTGCGGGGGTGCCCTGATCCATGCCCGCTTCGTGATGA
CCGCGGCCAGCTGCTTCCAAAGCCAGAACCCCGGGGTTAGCACCGTGGTGCTGGGTGCCTATGACCTGAGGCGGCGGGAGAGGCAGTCCC
GCCAGACGTTTTCCATCAGCAGCATGAGCGAGAATGGCTACGACCCCCAGCAGAACCTGAACGACCTGATGCTGCTTCAGCTGGACCGTG
AGGCCAACCTCACCAGCAGCGTGACGATACTGCCACTGCCTCTGCAGAACGCCACGGTGGAAGCCGGCACCAGATGCCAGGTGGCCGGCT
GGGGGAGCCAGCGCAGTGGGGGGCGTCTCTCCCGTTTTCCCAGGTTTGTCAACGTGACTGTGACCCCCGAGGACCAGTGTCGCCCCAACA
ACGTGTGCACCGGTGTGCTCACCCGCCGCGGTGGCATCTGCAATGGGGACGGGGGCACCCCCCTCGTCTGCGAGGGCCTGGCCCACGGCG
TGGCCTCCTTTTCCCTGGGGCCCTGTGGCCGAGGCCCTGACTTCTTCACCCGAGTGGCGCTCTTCCGAGACTGGATCGATGGTGTTCTCA
ACAACCCGGGACCGGGGCCAGCCTAGGGGGGCCTGTGACCTCCCATGGAGCCCAGCCCCGCCCTCCACACCTCCGGCGCTCCGCACCCAC
CTCCCACGGCCCCGCCCCTGCCCCCGCTCCGGCCAGAGGGGCCCTGGCTGTAATAAAGAAGCCGATCTCTCCTCTG

>523_523_1_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000309868_AZU1_chr19_828230_ENST00000233997_length(amino acids)=798AA_BP=567
MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTRCDSCRDFIT
GEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT
CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKK
LKHRRTSETSISPPGSSIGSPNRVICAKVDNEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI
YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGPESGRSSPYHSQLDVRSSTPTSYQAPKHFHIPAGDSNIYRKPPIYKRH
GDLSTATKSKTSEDISQTSKYSPIYSPDPYYASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYAD
PWTPPRSSTSSREALHTAGYEMSLNGCSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA
YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVT
VTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNPGPGPA

--------------------------------------------------------------
>523_523_2_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000326685_AZU1_chr19_828230_ENST00000233997_length(transcript)=2511nt_BP=1673nt
GAGCGGCCGCGCCCCCTGCGCTGCCAACCCGCGAGCCCGCATCATGGATGTCGAGCTCCCCTATTTCGCATTGCTAGCCCTGGAATTCGA
GACCCCAGACGAGGACCAGGATTCATGAAATCAGTCGCAGGGGCCGGGGCAGGGGCCTCTGGCTCCCGACACTGGCCGAGAGGTGATGAG
TGAGGTTCGAAGAACGGAAGATTTAAAAAGCAGCCGGGGCCTCCGTATTGAATGAAAGACCCAGTGCAAAGACATCACCATGAACACTAG
CATTCCTTATCAGCAGAATCCTTACAATCCACGGGGCAGCTCCAATGTCATCCAGTGCTACCGCTGTGGAGACACCTGCAAAGGGGAAGT
GGTCCGCGTGCACAACAACCACTTCCACATCAGATGCTTCACCTGTCAAGTATGTGGCTGTGGCCTGGCCCAGTCAGGCTTCTTCTTCAA
GAACCAGGAGTACATCTGCACCCAGGACTACCAGCAACTCTATGGCACCCGCTGTGACAGCTGCCGGGACTTCATCACAGGCGAAGTCAT
CTCGGCCCTGGGCCGCACTTACCACCCCAAGTGCTTCGTGTGCAGCTTGTGCAGGAAGCCTTTCCCCATTGGAGACAAGGTGACCTTCAG
CGGTAAAGAATGTGTGTGCCAAACGTGCTCCCAGTCCATGGCCAGCAGTAAGCCCATCAAGATTCGTGGACCAAGCCACTGTGCCGGGTG
CAAGGAGGAGATCAAGCACGGCCAGTCACTCCTGGCTCTGGACAAGCAGTGGCACGTCAGCTGCTTCAAGTGCCAGACCTGCAGCGTCAT
CCTCACCGGGGAGTATATCAGCAAGGATGGTGTTCCATACTGTGAGTCCGACTACCATGCCCAGTTTGGCATTAAATGTGAGACTTGTGA
CCGATACATCAGTGGCAGAGTCTTGGAGGCAGGAGGGAAGCACTACCACCCAACCTGTGCCAGGTGTGTACGCTGCCACCAGATGTTCAC
CGAAGGAGAGGAAATGTACCTCACAGGTTCCGAGGTTTGGCACCCCATCTGCAAACAGGCAGCCCGGGCAGAGAAGAAGTTAAAGCATAG
ACGGACATCTGAAACCTCCATCTCACCCCCTGGATCCAGCATTGGGTCACCCAACCGAGTCATCTGCGACATCTACGAGAACCTGGACCT
CCGGCAGAGACGGGCCTCCAGCCCGGGGTACATAGACTCCCCCACCTACAGCCGGCAGGGCATGTCCCCCACCTTCTCCCGCTCACCTCA
CCACTACTACCGCTCTGCTGGAGACAGTAACATCTACCGGAAACCCCCGATCTACAAACGGCATGGTGATTTGTCTACAGCAACCAAGAG
CAAAACAAGTGAAGACATCAGCCAGACCTCCAAGTACAGTCCCATCTACTCGCCAGACCCCTACTATGCTTCGGAGTCTGAGTACTGGAC
CTACCATGGGTCCCCCAAAGTGCCCCGAGCCAGAAGGTTCTCGTCTGGAGGAGAGGAGGATGATTTTGACCGCAGCATGCACAAGCTCCA
AAGTGGAATTGGCCGGCTGATTCTGAAGGAAGAAATGAAGGCCCGGTCGAGCTCCTATGCAGATCCCTGGACCCCTCCCCGGAGCTCCAC
CAGCAGCCGGGAAGCCCTGCACACAGCTGGCTATGAGATGTCCCTCAATGGCTGCTCCAGCCCCCTTTTGGACATCGTTGGCGGCCGGAA
GGCGAGGCCCCGCCAGTTCCCGTTCCTGGCCTCCATTCAGAATCAAGGCAGGCACTTCTGCGGGGGTGCCCTGATCCATGCCCGCTTCGT
GATGACCGCGGCCAGCTGCTTCCAAAGCCAGAACCCCGGGGTTAGCACCGTGGTGCTGGGTGCCTATGACCTGAGGCGGCGGGAGAGGCA
GTCCCGCCAGACGTTTTCCATCAGCAGCATGAGCGAGAATGGCTACGACCCCCAGCAGAACCTGAACGACCTGATGCTGCTTCAGCTGGA
CCGTGAGGCCAACCTCACCAGCAGCGTGACGATACTGCCACTGCCTCTGCAGAACGCCACGGTGGAAGCCGGCACCAGATGCCAGGTGGC
CGGCTGGGGGAGCCAGCGCAGTGGGGGGCGTCTCTCCCGTTTTCCCAGGTTTGTCAACGTGACTGTGACCCCCGAGGACCAGTGTCGCCC
CAACAACGTGTGCACCGGTGTGCTCACCCGCCGCGGTGGCATCTGCAATGGGGACGGGGGCACCCCCCTCGTCTGCGAGGGCCTGGCCCA
CGGCGTGGCCTCCTTTTCCCTGGGGCCCTGTGGCCGAGGCCCTGACTTCTTCACCCGAGTGGCGCTCTTCCGAGACTGGATCGATGGTGT
TCTCAACAACCCGGGACCGGGGCCAGCCTAGGGGGGCCTGTGACCTCCCATGGAGCCCAGCCCCGCCCTCCACACCTCCGGCGCTCCGCA
CCCACCTCCCACGGCCCCGCCCCTGCCCCCGCTCCGGCCAGAGGGGCCCTGGCTGTAATAAAGAAGCCGATCTCTCCTCTG

>523_523_2_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000326685_AZU1_chr19_828230_ENST00000233997_length(amino acids)=703AA_BP=472
MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTRCDSCRDFIT
GEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT
CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKK
LKHRRTSETSISPPGSSIGSPNRVICDIYENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSAGDSNIYRKPPIYKRHGDLST
ATKSKTSEDISQTSKYSPIYSPDPYYASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYADPWTPP
RSSTSSREALHTAGYEMSLNGCSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRR
RERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPED
QCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNPGPGPA

--------------------------------------------------------------
>523_523_3_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000356541_AZU1_chr19_828230_ENST00000233997_length(transcript)=2455nt_BP=1617nt
GCGCCCCCTGCGCTGCCAACCCGCGAGCCCGCATCATGGATGTCGAGCTCCCCTATTTCGCATTGCTAGCCCTGGAATTCGAGACCCCAG
ACGAGGACCAGGATTCATGAAATCAGTCGCAGGGGCCGGGGCAGGGGCCTCTGGCTCCCGACACTGGCCGAGAGGTGATGAGTGAGGTTC
GAAGAACGGAAGATTTAAAAAGCAGCCGGGGCCTCCGTATTGAATGAAAGACCCAGTGCAAAGACATCACCATGAACACTAGCATTCCTT
ATCAGCAGAATCCTTACAATCCACGGGGCAGCTCCAATGTCATCCAGTGCTACCGCTGTGGAGACACCTGCAAAGGGGAAGTGGTCCGCG
TGCACAACAACCACTTCCACATCAGATGCTTCACCTGTCAAGTATGTGGCTGTGGCCTGGCCCAGTCAGGCTTCTTCTTCAAGAACCAGG
AGTACATCTGCACCCAGGACTACCAGCAACTCTATGGCACCCGCTGTGACAGCTGCCGGGACTTCATCACAGGCGAAGTCATCTCGGCCC
TGGGCCGCACTTACCACCCCAAGTGCTTCGTGTGCAGCTTGTGCAGGAAGCCTTTCCCCATTGGAGACAAGGTGACCTTCAGCGGTAAAG
AATGTGTGTGCCAAACGTGCTCCCAGTCCATGGCCAGCAGTAAGCCCATCAAGATTCGTGGACCAAGCCACTGTGCCGGGTGCAAGGAGG
AGATCAAGCACGGCCAGTCACTCCTGGCTCTGGACAAGCAGTGGCACGTCAGCTGCTTCAAGTGCCAGACCTGCAGCGTCATCCTCACCG
GGGAGTATATCAGCAAGGATGGTGTTCCATACTGTGAGTCCGACTACCATGCCCAGTTTGGCATTAAATGTGAGACTTGTGACCGATACA
TCAGTGGCAGAGTCTTGGAGGCAGGAGGGAAGCACTACCACCCAACCTGTGCCAGGTGTGTACGCTGCCACCAGATGTTCACCGAAGGAG
AGGAAATGTACCTCACAGGTTCCGAGGTTTGGCACCCCATCTGCAAACAGGCAGCCCGGGCAGAGAAGAAGTTAAAGCATAGACGGACAT
CTGAAACCTCCATCTCACCCCCTGGATCCAGCATTGGGTCACCCAACCGAGTCATCTGCGACATCTACGAGAACCTGGACCTCCGGCAGA
GACGGGCCTCCAGCCCGGGGTACATAGACTCCCCCACCTACAGCCGGCAGGGCATGTCCCCCACCTTCTCCCGCTCACCTCACCACTACT
ACCGCTCTGGTGATTTGTCTACAGCAACCAAGAGCAAAACAAGTGAAGACATCAGCCAGACCTCCAAGTACAGTCCCATCTACTCGCCAG
ACCCCTACTATGCTTCGGAGTCTGAGTACTGGACCTACCATGGGTCCCCCAAAGTGCCCCGAGCCAGAAGGTTCTCGTCTGGAGGAGAGG
AGGATGATTTTGACCGCAGCATGCACAAGCTCCAAAGTGGAATTGGCCGGCTGATTCTGAAGGAAGAAATGAAGGCCCGGTCGAGCTCCT
ATGCAGATCCCTGGACCCCTCCCCGGAGCTCCACCAGCAGCCGGGAAGCCCTGCACACAGCTGGCTATGAGATGTCCCTCAATGGCTGCT
CCAGCCCCCTTTTGGACATCGTTGGCGGCCGGAAGGCGAGGCCCCGCCAGTTCCCGTTCCTGGCCTCCATTCAGAATCAAGGCAGGCACT
TCTGCGGGGGTGCCCTGATCCATGCCCGCTTCGTGATGACCGCGGCCAGCTGCTTCCAAAGCCAGAACCCCGGGGTTAGCACCGTGGTGC
TGGGTGCCTATGACCTGAGGCGGCGGGAGAGGCAGTCCCGCCAGACGTTTTCCATCAGCAGCATGAGCGAGAATGGCTACGACCCCCAGC
AGAACCTGAACGACCTGATGCTGCTTCAGCTGGACCGTGAGGCCAACCTCACCAGCAGCGTGACGATACTGCCACTGCCTCTGCAGAACG
CCACGGTGGAAGCCGGCACCAGATGCCAGGTGGCCGGCTGGGGGAGCCAGCGCAGTGGGGGGCGTCTCTCCCGTTTTCCCAGGTTTGTCA
ACGTGACTGTGACCCCCGAGGACCAGTGTCGCCCCAACAACGTGTGCACCGGTGTGCTCACCCGCCGCGGTGGCATCTGCAATGGGGACG
GGGGCACCCCCCTCGTCTGCGAGGGCCTGGCCCACGGCGTGGCCTCCTTTTCCCTGGGGCCCTGTGGCCGAGGCCCTGACTTCTTCACCC
GAGTGGCGCTCTTCCGAGACTGGATCGATGGTGTTCTCAACAACCCGGGACCGGGGCCAGCCTAGGGGGGCCTGTGACCTCCCATGGAGC
CCAGCCCCGCCCTCCACACCTCCGGCGCTCCGCACCCACCTCCCACGGCCCCGCCCCTGCCCCCGCTCCGGCCAGAGGGGCCCTGGCTGT
AATAAAGAAGCCGATCTCTCCTCTG

>523_523_3_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000356541_AZU1_chr19_828230_ENST00000233997_length(amino acids)=687AA_BP=456
MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTRCDSCRDFIT
GEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT
CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKK
LKHRRTSETSISPPGSSIGSPNRVICDIYENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGDLSTATKSKTSEDISQTSKY
SPIYSPDPYYASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYADPWTPPRSSTSSREALHTAGYE
MSLNGCSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSE
NGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRG
GICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNPGPGPA

--------------------------------------------------------------
>523_523_4_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000504238_AZU1_chr19_828230_ENST00000233997_length(transcript)=2479nt_BP=1641nt
CAATCTGAGGAGCAGGAGGACCGGGGCGCCGGTGTCCTGCCGCCTCCTTCTCCTTGCTCTCACCTGCGCCTATTAGTCCACGCGCCTTCA
AGGCCAGGGGCTACAGCCCAGACAGAGAGGGGACAGCAGAGGGAGAGAGAGCACCTGAGGATACAGAGCTGGCACTGGACTGCCTTTTCA
CCCCCCAGGTGATGAGTGAGGTTCGAAGAACGGAAGATTTAAAAAGCAGCCGGGGCCTCCGTATTGAATGAAAGACCCAGTGCAAAGACA
TCACCATGAACACTAGCATTCCTTATCAGCAGAATCCTTACAATCCACGGGGCAGCTCCAATGTCATCCAGTGCTACCGCTGTGGAGACA
CCTGCAAAGGGGAAGTGGTCCGCGTGCACAACAACCACTTCCACATCAGATGCTTCACCTGTCAAGTATGTGGCTGTGGCCTGGCCCAGT
CAGGCTTCTTCTTCAAGAACCAGGAGTACATCTGCACCCAGGACTACCAGCAACTCTATGGCACCCGCTGTGACAGCTGCCGGGACTTCA
TCACAGGCGAAGTCATCTCGGCCCTGGGCCGCACTTACCACCCCAAGTGCTTCGTGTGCAGCTTGTGCAGGAAGCCTTTCCCCATTGGAG
ACAAGGTGACCTTCAGCGGTAAAGAATGTGTGTGCCAAACGTGCTCCCAGTCCATGGCCAGCAGTAAGCCCATCAAGATTCGTGGACCAA
GCCACTGTGCCGGGTGCAAGGAGGAGATCAAGCACGGCCAGTCACTCCTGGCTCTGGACAAGCAGTGGCACGTCAGCTGCTTCAAGTGCC
AGACCTGCAGCGTCATCCTCACCGGGGAGTATATCAGCAAGGATGGTGTTCCATACTGTGAGTCCGACTACCATGCCCAGTTTGGCATTA
AATGTGAGACTTGTGACCGATACATCAGTGGCAGAGTCTTGGAGGCAGGAGGGAAGCACTACCACCCAACCTGTGCCAGGTGTGTACGCT
GCCACCAGATGTTCACCGAAGGAGAGGAAATGTACCTCACAGGTTCCGAGGTTTGGCACCCCATCTGCAAACAGGCAGCCCGGGCAGAGA
AGAAGTTAAAGCATAGACGGACATCTGAAACCTCCATCTCACCCCCTGGATCCAGCATTGGGTCACCCAACCGAGTCATCTGCGACATCT
ACGAGAACCTGGACCTCCGGCAGAGACGGGCCTCCAGCCCGGGGTACATAGACTCCCCCACCTACAGCCGGCAGGGCATGTCCCCCACCT
TCTCCCGCTCACCTCACCACTACTACCGCTCTGGTGATTTGTCTACAGCAACCAAGAGCAAAACAAGTGAAGACATCAGCCAGACCTCCA
AGTACAGTCCCATCTACTCGCCAGACCCCTACTATGCTTCGGAGTCTGAGTACTGGACCTACCATGGGTCCCCCAAAGTGCCCCGAGCCA
GAAGGTTCTCGTCTGGAGGAGAGGAGGATGATTTTGACCGCAGCATGCACAAGCTCCAAAGTGGAATTGGCCGGCTGATTCTGAAGGAAG
AAATGAAGGCCCGGTCGAGCTCCTATGCAGATCCCTGGACCCCTCCCCGGAGCTCCACCAGCAGCCGGGAAGCCCTGCACACAGCTGGCT
ATGAGATGTCCCTCAATGGCTGCTCCAGCCCCCTTTTGGACATCGTTGGCGGCCGGAAGGCGAGGCCCCGCCAGTTCCCGTTCCTGGCCT
CCATTCAGAATCAAGGCAGGCACTTCTGCGGGGGTGCCCTGATCCATGCCCGCTTCGTGATGACCGCGGCCAGCTGCTTCCAAAGCCAGA
ACCCCGGGGTTAGCACCGTGGTGCTGGGTGCCTATGACCTGAGGCGGCGGGAGAGGCAGTCCCGCCAGACGTTTTCCATCAGCAGCATGA
GCGAGAATGGCTACGACCCCCAGCAGAACCTGAACGACCTGATGCTGCTTCAGCTGGACCGTGAGGCCAACCTCACCAGCAGCGTGACGA
TACTGCCACTGCCTCTGCAGAACGCCACGGTGGAAGCCGGCACCAGATGCCAGGTGGCCGGCTGGGGGAGCCAGCGCAGTGGGGGGCGTC
TCTCCCGTTTTCCCAGGTTTGTCAACGTGACTGTGACCCCCGAGGACCAGTGTCGCCCCAACAACGTGTGCACCGGTGTGCTCACCCGCC
GCGGTGGCATCTGCAATGGGGACGGGGGCACCCCCCTCGTCTGCGAGGGCCTGGCCCACGGCGTGGCCTCCTTTTCCCTGGGGCCCTGTG
GCCGAGGCCCTGACTTCTTCACCCGAGTGGCGCTCTTCCGAGACTGGATCGATGGTGTTCTCAACAACCCGGGACCGGGGCCAGCCTAGG
GGGGCCTGTGACCTCCCATGGAGCCCAGCCCCGCCCTCCACACCTCCGGCGCTCCGCACCCACCTCCCACGGCCCCGCCCCTGCCCCCGC
TCCGGCCAGAGGGGCCCTGGCTGTAATAAAGAAGCCGATCTCTCCTCTG

>523_523_4_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000504238_AZU1_chr19_828230_ENST00000233997_length(amino acids)=687AA_BP=456
MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTRCDSCRDFIT
GEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT
CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKK
LKHRRTSETSISPPGSSIGSPNRVICDIYENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGDLSTATKSKTSEDISQTSKY
SPIYSPDPYYASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYADPWTPPRSSTSSREALHTAGYE
MSLNGCSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSE
NGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRG
GICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNPGPGPA

--------------------------------------------------------------
>523_523_5_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000506113_AZU1_chr19_828230_ENST00000233997_length(transcript)=3019nt_BP=2181nt
GGCCGGGGCAGGGGCCTCTGGCTCCCGACACTGGCCGAGAGGTGGGTTCCGGGGCGGGTCGCTGCTCCTTGAAGCCGGGCGGGGACGCGC
TGCCCCCGCCCTGCCTCCCTGTGGTCCACACCCCCTTTGGGCTCCGGAGCCGCTGGGCAGGAATAGTCCGGGGTGCGCGCGAGCAGGCGC
TGCCAACCCCACTTCTGCCCGGGATTCCAATCTGAGGAGCAGGAGGACCGGGGCGCCGGTGTCCTGCCGCCTCCTTCTCCTTGCTCTCAC
CTGCGCCTATTAGTCCACGCGCCTTCAAGGCCAGGGGCTACAGCCCAGACAGAGAGGGGACAGCAGAGGGAGAGAGAGCACCTGAGGATA
CAGAGCTGGCACTGGACTGCCTTTTCACCCCCCAGGTGATGAGTGAGGTTCGAAGAACGGAAGATTTAAAAAGCAGCCGGGGCCTCCGTA
TTGAATGAAAGACCCAGTGCAAAGACATCACCATGAACACTAGCATTCCTTATCAGCAGAATCCTTACAATCCACGGGGCAGCTCCAATG
TCATCCAGTGCTACCGCTGTGGAGACACCTGCAAAGGGGAAGTGGTCCGCGTGCACAACAACCACTTCCACATCAGATGCTTCACCTGTC
AAGTATGTGGCTGTGGCCTGGCCCAGTCAGGCTTCTTCTTCAAGAACCAGGAGTACATCTGCACCCAGGACTACCAGCAACTCTATGGCA
CCCGCTGTGACAGCTGCCGGGACTTCATCACAGGCGAAGTCATCTCGGCCCTGGGCCGCACTTACCACCCCAAGTGCTTCGTGTGCAGCT
TGTGCAGGAAGCCTTTCCCCATTGGAGACAAGGTGACCTTCAGCGGTAAAGAATGTGTGTGCCAAACGTGCTCCCAGTCCATGGCCAGCA
GTAAGCCCATCAAGATTCGTGGACCAAGCCACTGTGCCGGGTGCAAGGAGGAGATCAAGCACGGCCAGTCACTCCTGGCTCTGGACAAGC
AGTGGCACGTCAGCTGCTTCAAGTGCCAGACCTGCAGCGTCATCCTCACCGGGGAGTATATCAGCAAGGATGGTGTTCCATACTGTGAGT
CCGACTACCATGCCCAGTTTGGCATTAAATGTGAGACTTGTGACCGATACATCAGTGGCAGAGTCTTGGAGGCAGGAGGGAAGCACTACC
ACCCAACCTGTGCCAGGTGTGTACGCTGCCACCAGATGTTCACCGAAGGAGAGGAAATGTACCTCACAGGTTCCGAGGTTTGGCACCCCA
TCTGCAAACAGGCAGCCCGGGCAGAGAAGAAGTTAAAGCATAGACGGACATCTGAAACCTCCATCTCACCCCCTGGATCCAGCATTGGGT
CACCCAACCGAGTCATCTGCGCTAAAGTGGATAATGAGATCCTTAATTACAAAGACCTGGCGGCTCTCCCCAAGGTTAAGTCTATCTACG
AGGTACAACGCCCCGACCTCATTTCCTATGAGCCTCATTCCAGATACATGTCCGACGAGATGCTGGAGAGATGTGGCTATGGAGAGTCGC
TGGGAACATTATCTCCCTACTCCCAGGACATCTACGAGAACCTGGACCTCCGGCAGAGACGGGCCTCCAGCCCGGGGTACATAGACTCCC
CCACCTACAGCCGGCAGGGCATGTCCCCCACCTTCTCCCGCTCACCTCACCACTACTACCGCTCTGGGCCCGAGAGTGGCCGGAGCTCTC
CATACCATAGCCAGTTAGATGTGAGGTCCTCCACTCCAACCTCTTACCAGGCTCCCAAGCACTTTCACATCCCAGCTGGAGACAGTAACA
TCTACCGGAAACCCCCGATCTACAAACGGCATGGTGATTTGTCTACAGCAACCAAGAGCAAAACAAGTGAAGACATCAGCCAGACCTCCA
AGTACAGTCCCATCTACTCGCCAGACCCCTACTATGCTTCGGAGTCTGAGTACTGGACCTACCATGGGTCCCCCAAAGTGCCCCGAGCCA
GAAGGTTCTCGTCTGGAGGAGAGGAGGATGATTTTGACCGCAGCATGCACAAGCTCCAAAGTGGAATTGGCCGGCTGATTCTGAAGGAAG
AAATGAAGGCCCGGTCGAGCTCCTATGCAGATCCCTGGACCCCTCCCCGGAGCTCCACCAGCAGCCGGGAAGCCCTGCACACAGCTGGCT
ATGAGATGTCCCTCAATGGCTGCTCCAGCCCCCTTTTGGACATCGTTGGCGGCCGGAAGGCGAGGCCCCGCCAGTTCCCGTTCCTGGCCT
CCATTCAGAATCAAGGCAGGCACTTCTGCGGGGGTGCCCTGATCCATGCCCGCTTCGTGATGACCGCGGCCAGCTGCTTCCAAAGCCAGA
ACCCCGGGGTTAGCACCGTGGTGCTGGGTGCCTATGACCTGAGGCGGCGGGAGAGGCAGTCCCGCCAGACGTTTTCCATCAGCAGCATGA
GCGAGAATGGCTACGACCCCCAGCAGAACCTGAACGACCTGATGCTGCTTCAGCTGGACCGTGAGGCCAACCTCACCAGCAGCGTGACGA
TACTGCCACTGCCTCTGCAGAACGCCACGGTGGAAGCCGGCACCAGATGCCAGGTGGCCGGCTGGGGGAGCCAGCGCAGTGGGGGGCGTC
TCTCCCGTTTTCCCAGGTTTGTCAACGTGACTGTGACCCCCGAGGACCAGTGTCGCCCCAACAACGTGTGCACCGGTGTGCTCACCCGCC
GCGGTGGCATCTGCAATGGGGACGGGGGCACCCCCCTCGTCTGCGAGGGCCTGGCCCACGGCGTGGCCTCCTTTTCCCTGGGGCCCTGTG
GCCGAGGCCCTGACTTCTTCACCCGAGTGGCGCTCTTCCGAGACTGGATCGATGGTGTTCTCAACAACCCGGGACCGGGGCCAGCCTAGG
GGGGCCTGTGACCTCCCATGGAGCCCAGCCCCGCCCTCCACACCTCCGGCGCTCCGCACCCACCTCCCACGGCCCCGCCCCTGCCCCCGC
TCCGGCCAGAGGGGCCCTGGCTGTAATAAAGAAGCCGATCTCTCCTCTG

>523_523_5_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000506113_AZU1_chr19_828230_ENST00000233997_length(amino acids)=798AA_BP=567
MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTRCDSCRDFIT
GEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT
CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKK
LKHRRTSETSISPPGSSIGSPNRVICAKVDNEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI
YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGPESGRSSPYHSQLDVRSSTPTSYQAPKHFHIPAGDSNIYRKPPIYKRH
GDLSTATKSKTSEDISQTSKYSPIYSPDPYYASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYAD
PWTPPRSSTSSREALHTAGYEMSLNGCSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA
YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVT
VTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNPGPGPA

--------------------------------------------------------------
>523_523_6_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000508983_AZU1_chr19_828230_ENST00000233997_length(transcript)=2487nt_BP=1649nt
CAGCCGGGGCCTCCGTATTGAATGAAAGACCCAGTGCAAAGACATCACCATGAACACTAGCATTCCTTATCAGCAGAATCCTTACAATCC
ACGGGGCAGCTCCAATGTCATCCAGTGCTACCGCTGTGGAGACACCTGCAAAGGGGAAGTGGTCCGCGTGCACAACAACCACTTCCACAT
CAGATGCTTCACCTGTCAAGTATGTGGCTGTGGCCTGGCCCAGTCAGGCTTCTTCTTCAAGAACCAGGAGTACATCTGCACCCAGGACTA
CCAGCAACTCTATGGCACCCGCTGTGACAGCTGCCGGGACTTCATCACAGGCGAAGTCATCTCGGCCCTGGGCCGCACTTACCACCCCAA
GTGCTTCGTGTGCAGCTTGTGCAGGAAGCCTTTCCCCATTGGAGACAAGGTGACCTTCAGCGGTAAAGAATGTGTGTGCCAAACGTGCTC
CCAGTCCATGGCCAGCAGTAAGCCCATCAAGATTCGTGGACCAAGCCACTGTGCCGGGTGCAAGGAGGAGATCAAGCACGGCCAGTCACT
CCTGGCTCTGGACAAGCAGTGGCACGTCAGCTGCTTCAAGTGCCAGACCTGCAGCGTCATCCTCACCGGGGAGTATATCAGCAAGGATGG
TGTTCCATACTGTGAGTCCGACTACCATGCCCAGTTTGGCATTAAATGTGAGACTTGTGACCGATACATCAGTGGCAGAGTCTTGGAGGC
AGGAGGGAAGCACTACCACCCAACCTGTGCCAGGTGTGTACGCTGCCACCAGATGTTCACCGAAGGAGAGGAAATGTACCTCACAGGTTC
CGAGGTTTGGCACCCCATCTGCAAACAGGCAGCCCGGGCAGAGAAGAAGTTAAAGCATAGACGGACATCTGAAACCTCCATCTCACCCCC
TGGATCCAGCATTGGGTCACCCAACCGAGTCATCTGCGCTAAAGTGGATAATGAGATCCTTAATTACAAAGACCTGGCGGCTCTCCCCAA
GGTTAAGTCTATCTACGAGGTACAACGCCCCGACCTCATTTCCTATGAGCCTCATTCCAGATACATGTCCGACGAGATGCTGGAGAGATG
TGGCTATGGAGAGTCGCTGGGAACATTATCTCCCTACTCCCAGGACATCTACGAGAACCTGGACCTCCGGCAGAGACGGGCCTCCAGCCC
GGGGTACATAGACTCCCCCACCTACAGCCGGCAGGGCATGTCCCCCACCTTCTCCCGCTCACCTCACCACTACTACCGCTCTGCTGGAGA
CAGTAACATCTACCGGAAACCCCCGATCTACAAACGGCATGGTGATTTGTCTACAGCAACCAAGAGCAAAACAAGTGAAGACATCAGCCA
GACCTCCAAGTACAGTCCCATCTACTCGCCAGACCCCTACTATGCTTCGGAGTCTGAGTACTGGACCTACCATGGGTCCCCCAAAGTGCC
CCGAGCCAGAAGGTTCTCGTCTGGAGGAGAGGAGGATGATTTTGACCGCAGCATGCACAAGCTCCAAAGTGGAATTGGCCGGCTGATTCT
GAAGGAAGAAATGAAGGCCCGGTCGAGCTCCTATGCAGATCCCTGGACCCCTCCCCGGAGCTCCACCAGCAGCCGGGAAGCCCTGCACAC
AGCTGGCTATGAGATGTCCCTCAATGGCTGCTCCAGCCCCCTTTTGGACATCGTTGGCGGCCGGAAGGCGAGGCCCCGCCAGTTCCCGTT
CCTGGCCTCCATTCAGAATCAAGGCAGGCACTTCTGCGGGGGTGCCCTGATCCATGCCCGCTTCGTGATGACCGCGGCCAGCTGCTTCCA
AAGCCAGAACCCCGGGGTTAGCACCGTGGTGCTGGGTGCCTATGACCTGAGGCGGCGGGAGAGGCAGTCCCGCCAGACGTTTTCCATCAG
CAGCATGAGCGAGAATGGCTACGACCCCCAGCAGAACCTGAACGACCTGATGCTGCTTCAGCTGGACCGTGAGGCCAACCTCACCAGCAG
CGTGACGATACTGCCACTGCCTCTGCAGAACGCCACGGTGGAAGCCGGCACCAGATGCCAGGTGGCCGGCTGGGGGAGCCAGCGCAGTGG
GGGGCGTCTCTCCCGTTTTCCCAGGTTTGTCAACGTGACTGTGACCCCCGAGGACCAGTGTCGCCCCAACAACGTGTGCACCGGTGTGCT
CACCCGCCGCGGTGGCATCTGCAATGGGGACGGGGGCACCCCCCTCGTCTGCGAGGGCCTGGCCCACGGCGTGGCCTCCTTTTCCCTGGG
GCCCTGTGGCCGAGGCCCTGACTTCTTCACCCGAGTGGCGCTCTTCCGAGACTGGATCGATGGTGTTCTCAACAACCCGGGACCGGGGCC
AGCCTAGGGGGGCCTGTGACCTCCCATGGAGCCCAGCCCCGCCCTCCACACCTCCGGCGCTCCGCACCCACCTCCCACGGCCCCGCCCCT
GCCCCCGCTCCGGCCAGAGGGGCCCTGGCTGTAATAAAGAAGCCGATCTCTCCTCTG

>523_523_6_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000508983_AZU1_chr19_828230_ENST00000233997_length(amino acids)=765AA_BP=534
MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTRCDSCRDFIT
GEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT
CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKK
LKHRRTSETSISPPGSSIGSPNRVICAKVDNEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI
YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSAGDSNIYRKPPIYKRHGDLSTATKSKTSEDISQTSKYSPIYSPDPYYAS
ESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYADPWTPPRSSTSSREALHTAGYEMSLNGCSSPLLD
IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDL
MLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLV
CEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNPGPGPA

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>523_523_7_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000517451_AZU1_chr19_828230_ENST00000233997_length(transcript)=2719nt_BP=1881nt
CTAAGCCTCGATTGAAGGAGCACATCCCTTCCATTGAAGCTGCAGAGGAGCAGCTGCCACCCTGTGCACCCACACTTGCTTAAGGGTCTA
GCTGGATAACAAAAGGAGGCCCAGAATCGGTGGAGCTTGGAGATGAGCGAAGCAGTCCTGCACCAGGTTCTGAACTAATTAGCTGGTGGA
GGGGACAATACGAGTTTAAACAGCGGCTCTGGGTGCCTAAGATTCTACATTTTATACAGACATCCTTGGTTCCAGAGGGGGCTGAGCAGG
GGGGTCCGAGGTGAGTCTGTGAGCATGTGCAAGTCTGTACCAGCTTGTGAAGGACATGCCATGTCCCCTGAGTACTCATAGAAAGACACC
AACATGACAAAGGTAGTTTGGCTTTATACCTAGAAAAGGCCCCCAGGTCACAAGCTTCTCAGGACTTTGTGGGATTTTCCAGGTGGGCCC
TGAGGGGTGGCACTAAAGCAGACTCAAGAGGAGTCTGGGGTGGAGGTGGGTTGCTTGGAAAAGAGGGCGGAGGAAAAAGCTAAATGCAGT
CAGCCAGGAGGGGCTGCCCAGGACCCAAGTCAAAGAGAAGAATTTGAAAGCTTTGGAAGCAAGTGCTGTTGTGGGGGCTGCATAGCCCAG
GGCTGGCTGAAGCTGATCCACCACGCTCTGCCACTCTGGCTCCACAGAGCACAGAGCTTGTCCCTAAAGCTTCCTGTAGCTGACCATGAG
AAATGGTCATGCAGCCACACACACTTCCCCAGCCCCTCTCTCTGCTCTACCAGCCTGTCACCCACGTTTGGGCCACGAGAAGTCACTGCT
CTGTAAGTAGTTGTGACTGCAGTGGGTCTTTTTGGTCACCCCTGTCCTGGGCTTACTTCAGGTGGAAGCTTGAAGCTGGATGGCAGCTGA
GCCAGCAGACCGATTCTGACACTTACAGATGAGGAAACTAAGGCAGAGATGGTAGGACCTGCCCAGTGTTACAGCTGAGTAAAGTGGCAG
AGCTGGGACCAGAACCCAGGTTTGCTGACTCCCTGTCTAGCACTCCTTCCTTCAGGCTATGTAGTCCCTGAGCAGAATGTGGCATCTCAG
GTTGTGAGAAATGATGGAGTTCAAATTTATAACAAGGAAGGCTTCTAAAGGGCTAGGAAGGCTTCTAAAGGGCTGGGGCTCACCTGGGAC
CTGTCCAGTCTTATTTGAGGAGCCACACCCTTAGAGGTCATTCTGGAACAGACCTGGGAATCCATGGAATGTGCTGGAAAGAGCCCTGGG
CTGGGATCTGGTCCAGTTCTGGTGCTCACATGCTATGTGGTCTTAAGCAAGCCCCTTCCCCTCTCTGGTGCTCCAATTACTAAATGCAAA
ATGAGGGTTTGGCCCCAGTGCTTTTCCAGCTCCGATGCTCCATGGCCCAGTTCTAACAGAGAGCCCTGATCTTGAAGTGGACTCACTCCC
CTGGGCTGGAGCCTGGTAAAGATAGGAAAAGGGTACACAGTCCCATCCCGGTCACTCTGCCTTCCTGAAGTGCTCTCCTTGGGTCCTCTG
CAGGTGATTTGTCTACAGCAACCAAGAGCAAAACAAGTGAAGACATCAGCCAGACCTCCAAGTACAGTCCCATCTACTCGCCAGACCCCT
ACTATGCTTCGGAGTCTGAGTACTGGACCTACCATGGGTCCCCCAAAGTGCCCCGAGCCAGAAGGTTCTCGTCTGGAGGAGAGGAGGATG
ATTTTGACCGCAGCATGCACAAGCTCCAAAGTGGAATTGGCCGGCTGATTCTGAAGGAAGAAATGAAGGCCCGGTCGAGCTCCTATGCAG
ATCCCTGGACCCCTCCCCGGAGCTCCACCAGCAGCCGGGAAGCCCTGCACACAGCTGGCTATGAGATGTCCCTCAATGGCTGCTCCAGCC
CCCTTTTGGACATCGTTGGCGGCCGGAAGGCGAGGCCCCGCCAGTTCCCGTTCCTGGCCTCCATTCAGAATCAAGGCAGGCACTTCTGCG
GGGGTGCCCTGATCCATGCCCGCTTCGTGATGACCGCGGCCAGCTGCTTCCAAAGCCAGAACCCCGGGGTTAGCACCGTGGTGCTGGGTG
CCTATGACCTGAGGCGGCGGGAGAGGCAGTCCCGCCAGACGTTTTCCATCAGCAGCATGAGCGAGAATGGCTACGACCCCCAGCAGAACC
TGAACGACCTGATGCTGCTTCAGCTGGACCGTGAGGCCAACCTCACCAGCAGCGTGACGATACTGCCACTGCCTCTGCAGAACGCCACGG
TGGAAGCCGGCACCAGATGCCAGGTGGCCGGCTGGGGGAGCCAGCGCAGTGGGGGGCGTCTCTCCCGTTTTCCCAGGTTTGTCAACGTGA
CTGTGACCCCCGAGGACCAGTGTCGCCCCAACAACGTGTGCACCGGTGTGCTCACCCGCCGCGGTGGCATCTGCAATGGGGACGGGGGCA
CCCCCCTCGTCTGCGAGGGCCTGGCCCACGGCGTGGCCTCCTTTTCCCTGGGGCCCTGTGGCCGAGGCCCTGACTTCTTCACCCGAGTGG
CGCTCTTCCGAGACTGGATCGATGGTGTTCTCAACAACCCGGGACCGGGGCCAGCCTAGGGGGGCCTGTGACCTCCCATGGAGCCCAGCC
CCGCCCTCCACACCTCCGGCGCTCCGCACCCACCTCCCACGGCCCCGCCCCTGCCCCCGCTCCGGCCAGAGGGGCCCTGGCTGTAATAAA
GAAGCCGATCTCTCCTCTG

>523_523_7_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000517451_AZU1_chr19_828230_ENST00000233997_length(amino acids)=355AA_BP=1
MVLGGHSHVDKPGKTGETPPTALAPPAGHLASGAGFHRGVLQRQWQYRHAAGEVGLTVQLKQHQVVQVLLGVVAILAHAADGKRLAGLPL
PPPQVIGTQHHGANPGVLALEAAGRGHHEAGMDQGTPAEVPALILNGGQERELAGPRLPAANDVQKGAGAAIEGHLIASCVQGFPAAGGA
PGRGPGICIGARPGLHFFLQNQPANSTLELVHAAVKIILLSSRREPSGSGHFGGPMVGPVLRLRSIVGVWRVDGTVLGGLADVFTCFALG
CCRQITCRGPKESTSGRQSDRDGTVYPFPIFTRLQPRGVSPLQDQGSLLELGHGASELEKHWGQTLILHLVIGAPERGRGLLKTT

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Fusion Gene PPI Analysis for ABLIM3-AZU1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ABLIM3-AZU1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ABLIM3-AZU1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneABLIM3C0023893Liver Cirrhosis, Experimental1CTD_human