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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:CNOT1-GOT2 (FusionGDB2 ID:HG23019TG2806) |
Fusion Gene Summary for CNOT1-GOT2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CNOT1-GOT2 | Fusion gene ID: hg23019tg2806 | Hgene | Tgene | Gene symbol | CNOT1 | GOT2 | Gene ID | 23019 | 2806 |
| Gene name | CCR4-NOT transcription complex subunit 1 | glutamic-oxaloacetic transaminase 2 | |
| Synonyms | AD-005|CDC39|HPE12|NOT1|NOT1H | KAT4|KATIV|KYAT4|mitAAT | |
| Cytomap | ('CNOT1')('GOT2') 16q21 | 16q21 | |
| Type of gene | protein-coding | protein-coding | |
| Description | CCR4-NOT transcription complex subunit 1CCR4-associated factor 1NOT1 (negative regulator of transcription 1, yeast) homologadrenal gland protein AD-005negative regulator of transcription subunit 1 homolog | aspartate aminotransferase, mitochondrialFABP-1FABPpmaspartate aminotransferase 2aspartate transaminase 2fatty acid-binding proteinglutamate oxaloacetate transaminase 2glutamic-oxaloacetic transaminase 2, mitochondrialkynurenine aminotransferase 4 | |
| Modification date | 20200322 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000317147, ENST00000441024, ENST00000569240, ENST00000245138, ENST00000569732, | ||
| Fusion gene scores | * DoF score | 19 X 17 X 11=3553 | 7 X 9 X 3=189 |
| # samples | 21 | 9 | |
| ** MAII score | log2(21/3553*10)=-4.0805764556651 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/189*10)=-1.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CNOT1 [Title/Abstract] AND GOT2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | CNOT1(58608513)-GOT2(58757806), # samples:2 CNOT1(58663632)-GOT2(58757806), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | CNOT1-GOT2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CNOT1-GOT2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CNOT1-GOT2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CNOT1-GOT2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | CNOT1 | GO:0000122 | negative regulation of transcription by RNA polymerase II | 16778766 |
| Hgene | CNOT1 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly | 21976065 |
| Hgene | CNOT1 | GO:0017148 | negative regulation of translation | 24736845 |
| Hgene | CNOT1 | GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway | 16778766 |
| Hgene | CNOT1 | GO:0035195 | gene silencing by miRNA | 23172285|24768540 |
| Hgene | CNOT1 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway | 16778766 |
| Hgene | CNOT1 | GO:0060213 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening | 23644599 |
| Tgene | GOT2 | GO:0006533 | aspartate catabolic process | 2567216 |
| Tgene | GOT2 | GO:0045471 | response to ethanol | 9537447 |
| Fusion gene breakpoints across CNOT1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across GOT2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BLCA | TCGA-E7-A85H-01A | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - |
| ChimerDB4 | LUSC | TCGA-98-A539-01A | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58757806 | - |
| ChimerDB4 | LUSC | TCGA-98-A539 | CNOT1 | chr16 | 58663631 | - | GOT2 | chr16 | 58757806 | - |
| ChimerDB4 | LUSC | TCGA-98-A539 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58757806 | - |
| ChimerDB4 | LUSC | TCGA-98-A539 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58768212 | - |
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Fusion Gene ORF analysis for CNOT1-GOT2 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000317147 | ENST00000564400 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - |
| 5CDS-5UTR | ENST00000441024 | ENST00000564400 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - |
| 5CDS-5UTR | ENST00000569240 | ENST00000564400 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-3CDS | ENST00000317147 | ENST00000245206 | CNOT1 | chr16 | 58663631 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-3CDS | ENST00000317147 | ENST00000245206 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-3CDS | ENST00000317147 | ENST00000434819 | CNOT1 | chr16 | 58663631 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-3CDS | ENST00000317147 | ENST00000434819 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-3CDS | ENST00000441024 | ENST00000245206 | CNOT1 | chr16 | 58663631 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-3CDS | ENST00000441024 | ENST00000245206 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-3CDS | ENST00000441024 | ENST00000434819 | CNOT1 | chr16 | 58663631 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-3CDS | ENST00000441024 | ENST00000434819 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-3CDS | ENST00000569240 | ENST00000245206 | CNOT1 | chr16 | 58663631 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-3CDS | ENST00000569240 | ENST00000245206 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-3CDS | ENST00000569240 | ENST00000434819 | CNOT1 | chr16 | 58663631 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-3CDS | ENST00000569240 | ENST00000434819 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-5UTR | ENST00000317147 | ENST00000245206 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58768212 | - |
| 5UTR-5UTR | ENST00000317147 | ENST00000434819 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58768212 | - |
| 5UTR-5UTR | ENST00000317147 | ENST00000564400 | CNOT1 | chr16 | 58663631 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-5UTR | ENST00000317147 | ENST00000564400 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-5UTR | ENST00000317147 | ENST00000564400 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58768212 | - |
| 5UTR-5UTR | ENST00000441024 | ENST00000245206 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58768212 | - |
| 5UTR-5UTR | ENST00000441024 | ENST00000434819 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58768212 | - |
| 5UTR-5UTR | ENST00000441024 | ENST00000564400 | CNOT1 | chr16 | 58663631 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-5UTR | ENST00000441024 | ENST00000564400 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-5UTR | ENST00000441024 | ENST00000564400 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58768212 | - |
| 5UTR-5UTR | ENST00000569240 | ENST00000245206 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58768212 | - |
| 5UTR-5UTR | ENST00000569240 | ENST00000434819 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58768212 | - |
| 5UTR-5UTR | ENST00000569240 | ENST00000564400 | CNOT1 | chr16 | 58663631 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-5UTR | ENST00000569240 | ENST00000564400 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58757806 | - |
| 5UTR-5UTR | ENST00000569240 | ENST00000564400 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58768212 | - |
| In-frame | ENST00000317147 | ENST00000245206 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - |
| In-frame | ENST00000317147 | ENST00000434819 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - |
| In-frame | ENST00000441024 | ENST00000245206 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - |
| In-frame | ENST00000441024 | ENST00000434819 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - |
| In-frame | ENST00000569240 | ENST00000245206 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - |
| In-frame | ENST00000569240 | ENST00000434819 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - |
| intron-3CDS | ENST00000245138 | ENST00000245206 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - |
| intron-3CDS | ENST00000245138 | ENST00000245206 | CNOT1 | chr16 | 58663631 | - | GOT2 | chr16 | 58757806 | - |
| intron-3CDS | ENST00000245138 | ENST00000245206 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58757806 | - |
| intron-3CDS | ENST00000245138 | ENST00000434819 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - |
| intron-3CDS | ENST00000245138 | ENST00000434819 | CNOT1 | chr16 | 58663631 | - | GOT2 | chr16 | 58757806 | - |
| intron-3CDS | ENST00000245138 | ENST00000434819 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58757806 | - |
| intron-3CDS | ENST00000569732 | ENST00000245206 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - |
| intron-3CDS | ENST00000569732 | ENST00000245206 | CNOT1 | chr16 | 58663631 | - | GOT2 | chr16 | 58757806 | - |
| intron-3CDS | ENST00000569732 | ENST00000245206 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58757806 | - |
| intron-3CDS | ENST00000569732 | ENST00000434819 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - |
| intron-3CDS | ENST00000569732 | ENST00000434819 | CNOT1 | chr16 | 58663631 | - | GOT2 | chr16 | 58757806 | - |
| intron-3CDS | ENST00000569732 | ENST00000434819 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58757806 | - |
| intron-5UTR | ENST00000245138 | ENST00000245206 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58768212 | - |
| intron-5UTR | ENST00000245138 | ENST00000434819 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58768212 | - |
| intron-5UTR | ENST00000245138 | ENST00000564400 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - |
| intron-5UTR | ENST00000245138 | ENST00000564400 | CNOT1 | chr16 | 58663631 | - | GOT2 | chr16 | 58757806 | - |
| intron-5UTR | ENST00000245138 | ENST00000564400 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58757806 | - |
| intron-5UTR | ENST00000245138 | ENST00000564400 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58768212 | - |
| intron-5UTR | ENST00000569732 | ENST00000245206 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58768212 | - |
| intron-5UTR | ENST00000569732 | ENST00000434819 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58768212 | - |
| intron-5UTR | ENST00000569732 | ENST00000564400 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - |
| intron-5UTR | ENST00000569732 | ENST00000564400 | CNOT1 | chr16 | 58663631 | - | GOT2 | chr16 | 58757806 | - |
| intron-5UTR | ENST00000569732 | ENST00000564400 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58757806 | - |
| intron-5UTR | ENST00000569732 | ENST00000564400 | CNOT1 | chr16 | 58663632 | - | GOT2 | chr16 | 58768212 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000317147 | CNOT1 | chr16 | 58608513 | - | ENST00000245206 | GOT2 | chr16 | 58757806 | - | 4556 | 2312 | 312 | 3515 | 1067 |
| ENST00000317147 | CNOT1 | chr16 | 58608513 | - | ENST00000434819 | GOT2 | chr16 | 58757806 | - | 3740 | 2312 | 312 | 3386 | 1024 |
| ENST00000569240 | CNOT1 | chr16 | 58608513 | - | ENST00000245206 | GOT2 | chr16 | 58757806 | - | 4504 | 2260 | 260 | 3463 | 1067 |
| ENST00000569240 | CNOT1 | chr16 | 58608513 | - | ENST00000434819 | GOT2 | chr16 | 58757806 | - | 3688 | 2260 | 260 | 3334 | 1024 |
| ENST00000441024 | CNOT1 | chr16 | 58608513 | - | ENST00000245206 | GOT2 | chr16 | 58757806 | - | 4508 | 2264 | 264 | 3467 | 1067 |
| ENST00000441024 | CNOT1 | chr16 | 58608513 | - | ENST00000434819 | GOT2 | chr16 | 58757806 | - | 3692 | 2264 | 264 | 3338 | 1024 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000317147 | ENST00000245206 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - | 0.001280504 | 0.9987196 |
| ENST00000317147 | ENST00000434819 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - | 0.001371727 | 0.99862826 |
| ENST00000569240 | ENST00000245206 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - | 0.001224283 | 0.99877566 |
| ENST00000569240 | ENST00000434819 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - | 0.001309767 | 0.9986902 |
| ENST00000441024 | ENST00000245206 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - | 0.001229852 | 0.9987702 |
| ENST00000441024 | ENST00000434819 | CNOT1 | chr16 | 58608513 | - | GOT2 | chr16 | 58757806 | - | 0.001312599 | 0.99868745 |
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Fusion Genomic Features for CNOT1-GOT2 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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Fusion Protein Features for CNOT1-GOT2 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:58608513/chr16:58757806) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000317147 | - | 16 | 49 | 153_157 | 659 | 2377.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000317147 | - | 16 | 49 | 181_185 | 659 | 2377.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000317147 | - | 16 | 49 | 223_227 | 659 | 2377.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000317147 | - | 16 | 49 | 570_574 | 659 | 2377.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000441024 | - | 16 | 31 | 153_157 | 659 | 1552.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000441024 | - | 16 | 31 | 181_185 | 659 | 1552.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000441024 | - | 16 | 31 | 223_227 | 659 | 1552.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000441024 | - | 16 | 31 | 570_574 | 659 | 1552.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000569240 | - | 16 | 49 | 153_157 | 659 | 2372.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000569240 | - | 16 | 49 | 181_185 | 659 | 2372.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000569240 | - | 16 | 49 | 223_227 | 659 | 2372.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000569240 | - | 16 | 49 | 570_574 | 659 | 2372.0 | Motif | Note=LXXLL |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000317147 | - | 16 | 49 | 1333_1350 | 659 | 2377.0 | Compositional bias | Note=Thr-rich |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000441024 | - | 16 | 31 | 1333_1350 | 659 | 1552.0 | Compositional bias | Note=Thr-rich |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000569240 | - | 16 | 49 | 1333_1350 | 659 | 2372.0 | Compositional bias | Note=Thr-rich |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000317147 | - | 16 | 49 | 1639_1643 | 659 | 2377.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000317147 | - | 16 | 49 | 1942_1946 | 659 | 2377.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000317147 | - | 16 | 49 | 2096_2100 | 659 | 2377.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000441024 | - | 16 | 31 | 1639_1643 | 659 | 1552.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000441024 | - | 16 | 31 | 1942_1946 | 659 | 1552.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000441024 | - | 16 | 31 | 2096_2100 | 659 | 1552.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000569240 | - | 16 | 49 | 1639_1643 | 659 | 2372.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000569240 | - | 16 | 49 | 1942_1946 | 659 | 2372.0 | Motif | Note=LXXLL |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000569240 | - | 16 | 49 | 2096_2100 | 659 | 2372.0 | Motif | Note=LXXLL |
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Fusion Gene Sequence for CNOT1-GOT2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >17712_17712_1_CNOT1-GOT2_CNOT1_chr16_58608513_ENST00000317147_GOT2_chr16_58757806_ENST00000245206_length(transcript)=4556nt_BP=2312nt GAAATGGGAACGGGGAGGGGAAAGGCCGCGACGTGAGCGCGCGACCTCCGGCGCCATTTTGTAGAGAAACAAGCGGAGTTAACCGAAGAG GGGGTCGAGGAGAGCCGGAGTCGGGGACCCAGGAGTTTCCTGTGTCCAGCGCTGCCGGAGCCGCCTGAGGTGCCATGTTTCAGAACAGAG TAAGACCCCTGGTAAAGAAGAACTGAAGATATTATACAGATACCAGATATAGCCTAATTACAAAGAAAGCATTAACCTGCCTCTGAGGTG ACTAAAGGGGAATAATGGTGATTTTGCGCCGGGCTCGGCCGCCTGCTTCCGCCCCAACCAGCAATGAATCTTGACTCGCTCTCGCTGGCC TTGTCTCAAATCAGCTACCTGGTGGACAATTTAACCAAGAAAAATTACCGAGCCAGCCAGCAGGAAATACAGCATATTGTGAATCGGCAC GGTCCTGAGGCAGACAGGCATTTATTACGCTGCCTATTTTCGCATGTGGATTTCAGTGGCGATGGTAAAAGCAGTGGCAAAGATTTCCAT CAGACTCAGTTTCTGATTCAGGAGTGTGCGTTGCTGATTACAAAGCCAAATTTTATCTCGACGCTGTCCTATGCCATTGATAATCCATTG CACTATCAGAAGAGTTTAAAGCCTGCACCCCACTTATTTGCCCAGCTGAGTAAAGTGCTCAAATTAAGCAAAGTACAAGAGGTAATTTTT GGCCTTGCCCTGTTGAATTCTTCCAGCTCAGATCTTAGAGGTTTCGCTGCCCAGTTTATCAAACAGAAGCTTCCAGATCTTCTGCGTTCT TACATTGACGCAGACGTCAGTGGAAATCAAGAAGGTGGCTTCCAAGATATAGCAATAGAGGTCCTACACCTCCTCCTCTCCCATCTCCTC TTTGGGCAGAAGGGAGCCTTTGGAGTTGGACAAGAACAGATAGACGCTTTTCTTAAGACGCTGCGCAGAGATTTTCCCCAAGAACGCTGT CCCGTGGTGCTCGCACCACTTTTATACCCTGAAAAACGGGACATTCTAATGGACAGGATCCTGCCTGATTCCGGAGGGGTAGCTAAAACC ATGATGGAGAGCTCTTTGGCTGATTTCATGCAAGAAGTAGGCTATGGCTTTTGTGCAAGTATTGAAGAATGTCGCAATATAATCGTGCAG TTTGGTGTTCGGGAGGTCACAGCTGCCCAGGTTGCAAGGGTTTTGGGAATGATGGCTCGAACTCATTCAGGATTAACAGATGGCATTCCA TTACAGAGTATTTCTGCTCCGGGCAGTGGGATCTGGAGTGATGGGAAAGATAAAAGTGATGGAGCACAGGCACACACATGGAATGTAGAA GTCTTGATTGACGTTCTTAAAGAACTGAATCCAAGTTTGAATTTCAAGGAAGTAACTTATGAACTGGACCATCCTGGATTTCAAATTCGT GACAGTAAAGGACTTCATAATGTGGTTTATGGCATTCAGAGGGGTTTGGGTATGGAAGTGTTCCCAGTAGACCTCATATATAGACCTTGG AAACATGCTGAAGGCCAGCTCTCCTTCATTCAACATTCCCTTATAAATCCAGAGATCTTCTGTTTTGCTGACTATCCCTGTCATACTGTT GCCACTGATATTCTGAAAGCACCACCAGAGGATGACAATCGAGAAATTGCCACATGGAAGAGCTTGGATTTGATTGAATCTCTGCTGAGG CTTGCAGAGGTTGGGCAGTATGAGCAAGTCAAACAGCTCTTCAGCTTCCCTATCAAACACTGTCCAGACATGCTGGTATTGGCCTTACTA CAAATTAACACCTCTTGGCATACCTTGCGCCATGAACTTATCTCCACTCTGATGCCAATTTTCCTTGGAAACCATCCTAACTCAGCTATT ATTTTGCACTATGCATGGCATGGGCAGGGACAGTCTCCCTCAATTCGCCAACTTATCATGCATGCAATGGCAGAATGGTACATGAGAGGG GAGCAGTATGATCAGGCCAAATTGTCTCGAATACTTGATGTGGCCCAGGACTTGAAGGCCTTGTCAATGCTGCTAAATGGTACTCCATTT GCCTTTGTTATTGACCTTGCTGCACTTGCTTCACGTCGTGAATACCTCAAACTTGATAAGTGGCTCACAGATAAAATTCGAGAGCATGGG GAGCCTTTTATCCAGGCGTGTATGACTTTTTTAAAGAGACGGTGTCCTTCTATTTTGGGCGGACTTGCCCCAGAAAAAGACCAGCCCAAA AGTGCTCAACTTCCTCCAGAAACTTTGGCGACAATGTTGGCCTGTCTGCAAGCTTGTGCAGGCTCCTGGTGGACCCATGTGGAAATGGGA CCTCCAGATCCCATTCTGGGAGTCACTGAAGCCTTTAAGAGGGACACCAATAGCAAAAAGATGAATCTGGGAGTTGGTGCCTACCGGGAT GATAATGGAAAGCCTTACGTTCTGCCTAGCGTCCGCAAGGCAGAGGCCCAGATTGCCGCAAAAAATTTGGACAAGGAATACCTGCCCATT GGGGGACTGGCTGAATTTTGCAAGGCATCTGCAGAACTAGCCCTGGGTGAGAACAGCGAAGTCTTGAAGAGTGGCCGGTTTGTCACTGTG CAGACCATTTCTGGAACTGGAGCCTTAAGGATCGGAGCCAGTTTTCTGCAAAGATTTTTTAAGTTCAGCCGAGATGTCTTTCTGCCCAAA CCAACCTGGGGAAACCACACACCCATCTTCAGGGATGCTGGCATGCAGCTACAAGGTTATCGGTATTATGACCCCAAGACTTGCGGTTTT GACTTCACAGGCGCTGTGGAGGATATTTCAAAAATACCAGAGCAGAGTGTTCTTCTTCTGCATGCCTGCGCCCACAATCCCACGGGAGTG GACCCGCGTCCGGAACAGTGGAAGGAAATAGCAACAGTGGTGAAGAAAAGGAATCTCTTTGCGTTCTTTGACATGGCCTACCAAGGCTTT GCCAGTGGTGATGGTGATAAGGATGCCTGGGCTGTGCGCCACTTCATCGAACAGGGCATTAATGTTTGCCTCTGCCAATCATATGCCAAG AACATGGGCTTATATGGTGAGCGTGTAGGAGCCTTCACTATGGTCTGCAAAGATGCGGATGAAGCCAAAAGGGTAGAGTCACAGTTGAAG ATCTTGATCCGTCCCATGTATTCCAACCCTCCCCTCAATGGGGCCCGGATTGCTGCTGCCATTCTGAACACCCCAGATTTGCGAAAACAA TGGCTGCAAGAAGTGAAAGTCATGGCTGACCGCATCATTGGCATGCGGACTCAACTGGTCTCCAACCTCAAGAAGGAGGGTTCCACCCAC AATTGGCAACACATCACCGACCAAATTGGCATGTTCTGTTTCACAGGGCTAAAGCCTGAACAGGTGGAGCGGCTGATCAAGGAGTTCTCC ATCTACATGACAAAAGATGGCCGCATCTCTGTGGCAGGGGTCACCTCCAGCAACGTGGGCTACCTTGCCCATGCCATTCACCAGGTCACC AAGTAATGTCCCTGGTGCGAGGAAACAGAGACAACCTTTCTGTCTTCAGCCTCTGCTATTGAGAGCTTCACACAGACAATGAGAGAGGGT GGATGGTGGTGAGTGGATCATTTCTTTCAGCCACAGTGTGTAACACTCAGCATTTGAATGTTTCTCAGAAAAGAACATGTAGTGACACAG GGCAGAGGCATCCATGGCTGGCGTCTGGAATATTAAACCAAACTCTCCCCGGTCCTTTTTTCTCCAACTTTTCTCAAAGAGTTTACATGT GCAAGAAAGTCATCGCACCAAAAAACCTGTCAATTATGCCATTGCAATATTTCAGAAGCTTTAACTGAAGTGTCAGGTTCCTCGTGAGAA ACAGCACACGTTAGAGGCTTTGAGAGAAGGCCTAGTTCTGTCATGAGTAGTCGGCCTCGTGTCTGTCCTCCCATCTTGGAACAACCTTAT CAACAGGCCGCACTGCAGAAATGATGTTTTATGAAAACCAATGAGGCTGCTGCCACTCCAGCAAGGGAAATAATGCAGTTTCCTGTCTTA TTTAAGAAAAAGAGAAGGCTCTCTTTTCTCCCTTGTCATTGCCGTTCTTTTCCTTACACGCAAAGATTTTTTAACTATTGCAGATTTTCA TCCCATTCTACTGCTTGATTGACCATCAACTCCATCCTATCGAGATTTATTTAAGAATGAAGAACATAATTTTCTGCTGATGCTGTACCC TCACCCTTTTCAGCAAAGAATAGTGGAGAGTAGGAAACTGTACTTTATCTCGGCATCCTCTTGAATGATAGTGCAAGTTTCTCCAGTTGG GATGTTGTCTCTGCCCGGTTGGACCTCCTCCCTTTGTTGAATGTGGTGTGCAGCCTCTCATCTCACACTGTGAGTCCAGCGGCGCAGGGT GGTACCAGGAAAGAGGATATTCTAGGCTTTGCGTGCTGCTAGCTGGGTTCAGGCTTCACCCACTGGAAAGAACCACCATCTGCTCTAACC >17712_17712_1_CNOT1-GOT2_CNOT1_chr16_58608513_ENST00000317147_GOT2_chr16_58757806_ENST00000245206_length(amino acids)=1067AA_BP=667 MLPPQPAMNLDSLSLALSQISYLVDNLTKKNYRASQQEIQHIVNRHGPEADRHLLRCLFSHVDFSGDGKSSGKDFHQTQFLIQECALLIT KPNFISTLSYAIDNPLHYQKSLKPAPHLFAQLSKVLKLSKVQEVIFGLALLNSSSSDLRGFAAQFIKQKLPDLLRSYIDADVSGNQEGGF QDIAIEVLHLLLSHLLFGQKGAFGVGQEQIDAFLKTLRRDFPQERCPVVLAPLLYPEKRDILMDRILPDSGGVAKTMMESSLADFMQEVG YGFCASIEECRNIIVQFGVREVTAAQVARVLGMMARTHSGLTDGIPLQSISAPGSGIWSDGKDKSDGAQAHTWNVEVLIDVLKELNPSLN FKEVTYELDHPGFQIRDSKGLHNVVYGIQRGLGMEVFPVDLIYRPWKHAEGQLSFIQHSLINPEIFCFADYPCHTVATDILKAPPEDDNR EIATWKSLDLIESLLRLAEVGQYEQVKQLFSFPIKHCPDMLVLALLQINTSWHTLRHELISTLMPIFLGNHPNSAIILHYAWHGQGQSPS IRQLIMHAMAEWYMRGEQYDQAKLSRILDVAQDLKALSMLLNGTPFAFVIDLAALASRREYLKLDKWLTDKIREHGEPFIQACMTFLKRR CPSILGGLAPEKDQPKSAQLPPETLATMLACLQACAGSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKA EAQIAAKNLDKEYLPIGGLAEFCKASAELALGENSEVLKSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFLPKPTWGNHTPIFRDAG MQLQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDAWAVRH FIEQGINVCLCQSYAKNMGLYGERVGAFTMVCKDADEAKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLRKQWLQEVKVMADRIIG -------------------------------------------------------------- >17712_17712_2_CNOT1-GOT2_CNOT1_chr16_58608513_ENST00000317147_GOT2_chr16_58757806_ENST00000434819_length(transcript)=3740nt_BP=2312nt GAAATGGGAACGGGGAGGGGAAAGGCCGCGACGTGAGCGCGCGACCTCCGGCGCCATTTTGTAGAGAAACAAGCGGAGTTAACCGAAGAG GGGGTCGAGGAGAGCCGGAGTCGGGGACCCAGGAGTTTCCTGTGTCCAGCGCTGCCGGAGCCGCCTGAGGTGCCATGTTTCAGAACAGAG TAAGACCCCTGGTAAAGAAGAACTGAAGATATTATACAGATACCAGATATAGCCTAATTACAAAGAAAGCATTAACCTGCCTCTGAGGTG ACTAAAGGGGAATAATGGTGATTTTGCGCCGGGCTCGGCCGCCTGCTTCCGCCCCAACCAGCAATGAATCTTGACTCGCTCTCGCTGGCC TTGTCTCAAATCAGCTACCTGGTGGACAATTTAACCAAGAAAAATTACCGAGCCAGCCAGCAGGAAATACAGCATATTGTGAATCGGCAC GGTCCTGAGGCAGACAGGCATTTATTACGCTGCCTATTTTCGCATGTGGATTTCAGTGGCGATGGTAAAAGCAGTGGCAAAGATTTCCAT CAGACTCAGTTTCTGATTCAGGAGTGTGCGTTGCTGATTACAAAGCCAAATTTTATCTCGACGCTGTCCTATGCCATTGATAATCCATTG CACTATCAGAAGAGTTTAAAGCCTGCACCCCACTTATTTGCCCAGCTGAGTAAAGTGCTCAAATTAAGCAAAGTACAAGAGGTAATTTTT GGCCTTGCCCTGTTGAATTCTTCCAGCTCAGATCTTAGAGGTTTCGCTGCCCAGTTTATCAAACAGAAGCTTCCAGATCTTCTGCGTTCT TACATTGACGCAGACGTCAGTGGAAATCAAGAAGGTGGCTTCCAAGATATAGCAATAGAGGTCCTACACCTCCTCCTCTCCCATCTCCTC TTTGGGCAGAAGGGAGCCTTTGGAGTTGGACAAGAACAGATAGACGCTTTTCTTAAGACGCTGCGCAGAGATTTTCCCCAAGAACGCTGT CCCGTGGTGCTCGCACCACTTTTATACCCTGAAAAACGGGACATTCTAATGGACAGGATCCTGCCTGATTCCGGAGGGGTAGCTAAAACC ATGATGGAGAGCTCTTTGGCTGATTTCATGCAAGAAGTAGGCTATGGCTTTTGTGCAAGTATTGAAGAATGTCGCAATATAATCGTGCAG TTTGGTGTTCGGGAGGTCACAGCTGCCCAGGTTGCAAGGGTTTTGGGAATGATGGCTCGAACTCATTCAGGATTAACAGATGGCATTCCA TTACAGAGTATTTCTGCTCCGGGCAGTGGGATCTGGAGTGATGGGAAAGATAAAAGTGATGGAGCACAGGCACACACATGGAATGTAGAA GTCTTGATTGACGTTCTTAAAGAACTGAATCCAAGTTTGAATTTCAAGGAAGTAACTTATGAACTGGACCATCCTGGATTTCAAATTCGT GACAGTAAAGGACTTCATAATGTGGTTTATGGCATTCAGAGGGGTTTGGGTATGGAAGTGTTCCCAGTAGACCTCATATATAGACCTTGG AAACATGCTGAAGGCCAGCTCTCCTTCATTCAACATTCCCTTATAAATCCAGAGATCTTCTGTTTTGCTGACTATCCCTGTCATACTGTT GCCACTGATATTCTGAAAGCACCACCAGAGGATGACAATCGAGAAATTGCCACATGGAAGAGCTTGGATTTGATTGAATCTCTGCTGAGG CTTGCAGAGGTTGGGCAGTATGAGCAAGTCAAACAGCTCTTCAGCTTCCCTATCAAACACTGTCCAGACATGCTGGTATTGGCCTTACTA CAAATTAACACCTCTTGGCATACCTTGCGCCATGAACTTATCTCCACTCTGATGCCAATTTTCCTTGGAAACCATCCTAACTCAGCTATT ATTTTGCACTATGCATGGCATGGGCAGGGACAGTCTCCCTCAATTCGCCAACTTATCATGCATGCAATGGCAGAATGGTACATGAGAGGG GAGCAGTATGATCAGGCCAAATTGTCTCGAATACTTGATGTGGCCCAGGACTTGAAGGCCTTGTCAATGCTGCTAAATGGTACTCCATTT GCCTTTGTTATTGACCTTGCTGCACTTGCTTCACGTCGTGAATACCTCAAACTTGATAAGTGGCTCACAGATAAAATTCGAGAGCATGGG GAGCCTTTTATCCAGGCGTGTATGACTTTTTTAAAGAGACGGTGTCCTTCTATTTTGGGCGGACTTGCCCCAGAAAAAGACCAGCCCAAA AGTGCTCAACTTCCTCCAGAAACTTTGGCGACAATGTTGGCCTGTCTGCAAGCTTGTGCAGGCTCCTGGTGGACCCATGTGGAAATGGGA CCTCCAGATCCCATTCTGGGAGTCACTGAAGCCTTTAAGAGGGACACCAATAGCAAAAAGATGAATCTGGGAGTTGGTGCCTACCGGGAT GATAATGGAAAGCCTTACGTTCTGCCTAGCGTCCGCAAGTTTGTCACTGTGCAGACCATTTCTGGAACTGGAGCCTTAAGGATCGGAGCC AGTTTTCTGCAAAGATTTTTTAAGTTCAGCCGAGATGTCTTTCTGCCCAAACCAACCTGGGGAAACCACACACCCATCTTCAGGGATGCT GGCATGCAGCTACAAGGTTATCGGTATTATGACCCCAAGACTTGCGGTTTTGACTTCACAGGCGCTGTGGAGGATATTTCAAAAATACCA GAGCAGAGTGTTCTTCTTCTGCATGCCTGCGCCCACAATCCCACGGGAGTGGACCCGCGTCCGGAACAGTGGAAGGAAATAGCAACAGTG GTGAAGAAAAGGAATCTCTTTGCGTTCTTTGACATGGCCTACCAAGGCTTTGCCAGTGGTGATGGTGATAAGGATGCCTGGGCTGTGCGC CACTTCATCGAACAGGGCATTAATGTTTGCCTCTGCCAATCATATGCCAAGAACATGGGCTTATATGGTGAGCGTGTAGGAGCCTTCACT ATGGTCTGCAAAGATGCGGATGAAGCCAAAAGGGTAGAGTCACAGTTGAAGATCTTGATCCGTCCCATGTATTCCAACCCTCCCCTCAAT GGGGCCCGGATTGCTGCTGCCATTCTGAACACCCCAGATTTGCGAAAACAATGGCTGCAAGAAGTGAAAGTCATGGCTGACCGCATCATT GGCATGCGGACTCAACTGGTCTCCAACCTCAAGAAGGAGGGTTCCACCCACAATTGGCAACACATCACCGACCAAATTGGCATGTTCTGT TTCACAGGGCTAAAGCCTGAACAGGTGGAGCGGCTGATCAAGGAGTTCTCCATCTACATGACAAAAGATGGCCGCATCTCTGTGGCAGGG GTCACCTCCAGCAACGTGGGCTACCTTGCCCATGCCATTCACCAGGTCACCAAGTAATGTCCCTGGTGCGAGGAAACAGAGACAACCTTT CTGTCTTCAGCCTCTGCTATTGAGAGCTTCACACAGACAATGAGAGAGGGTGGATGGTGGTGAGTGGATCATTTCTTTCAGCCACAGTGT GTAACACTCAGCATTTGAATGTTTCTCAGAAAAGAACATGTAGTGACACAGGGCAGAGGCATCCATGGCTGGCGTCTGGAATATTAAACC AAACTCTCCCCGGTCCTTTTTTCTCCAACTTTTCTCAAAGAGTTTACATGTGCAAGAAAGTCATCGCACCAAAAAACCTGTCAATTATGC >17712_17712_2_CNOT1-GOT2_CNOT1_chr16_58608513_ENST00000317147_GOT2_chr16_58757806_ENST00000434819_length(amino acids)=1024AA_BP=667 MLPPQPAMNLDSLSLALSQISYLVDNLTKKNYRASQQEIQHIVNRHGPEADRHLLRCLFSHVDFSGDGKSSGKDFHQTQFLIQECALLIT KPNFISTLSYAIDNPLHYQKSLKPAPHLFAQLSKVLKLSKVQEVIFGLALLNSSSSDLRGFAAQFIKQKLPDLLRSYIDADVSGNQEGGF QDIAIEVLHLLLSHLLFGQKGAFGVGQEQIDAFLKTLRRDFPQERCPVVLAPLLYPEKRDILMDRILPDSGGVAKTMMESSLADFMQEVG YGFCASIEECRNIIVQFGVREVTAAQVARVLGMMARTHSGLTDGIPLQSISAPGSGIWSDGKDKSDGAQAHTWNVEVLIDVLKELNPSLN FKEVTYELDHPGFQIRDSKGLHNVVYGIQRGLGMEVFPVDLIYRPWKHAEGQLSFIQHSLINPEIFCFADYPCHTVATDILKAPPEDDNR EIATWKSLDLIESLLRLAEVGQYEQVKQLFSFPIKHCPDMLVLALLQINTSWHTLRHELISTLMPIFLGNHPNSAIILHYAWHGQGQSPS IRQLIMHAMAEWYMRGEQYDQAKLSRILDVAQDLKALSMLLNGTPFAFVIDLAALASRREYLKLDKWLTDKIREHGEPFIQACMTFLKRR CPSILGGLAPEKDQPKSAQLPPETLATMLACLQACAGSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKF VTVQTISGTGALRIGASFLQRFFKFSRDVFLPKPTWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNP TGVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTMVCKDADEAKRVES QLKILIRPMYSNPPLNGARIAAAILNTPDLRKQWLQEVKVMADRIIGMRTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIK -------------------------------------------------------------- >17712_17712_3_CNOT1-GOT2_CNOT1_chr16_58608513_ENST00000441024_GOT2_chr16_58757806_ENST00000245206_length(transcript)=4508nt_BP=2264nt CGGCGCCATTTTGTAGAGAAACAAGCGGAGTTAACCGAAGAGGGGGTCGAGGAGAGCCGGAGTCGGGGACCCAGGAGTTTCCTGTGTCCA GCGCTGCCGGAGCCGCCTGAGGTGCCATGTTTCAGAACAGAGTAAGACCCCTGGTAAAGAAGAACTGAAGATATTATACAGATACCAGAT ATAGCCTAATTACAAAGAAAGCATTAACCTGCCTCTGAGGTGACTAAAGGGGAATAATGGTGATTTTGCGCCGGGCTCGGCCGCCTGCTT CCGCCCCAACCAGCAATGAATCTTGACTCGCTCTCGCTGGCCTTGTCTCAAATCAGCTACCTGGTGGACAATTTAACCAAGAAAAATTAC CGAGCCAGCCAGCAGGAAATACAGCATATTGTGAATCGGCACGGTCCTGAGGCAGACAGGCATTTATTACGCTGCCTATTTTCGCATGTG GATTTCAGTGGCGATGGTAAAAGCAGTGGCAAAGATTTCCATCAGACTCAGTTTCTGATTCAGGAGTGTGCGTTGCTGATTACAAAGCCA AATTTTATCTCGACGCTGTCCTATGCCATTGATAATCCATTGCACTATCAGAAGAGTTTAAAGCCTGCACCCCACTTATTTGCCCAGCTG AGTAAAGTGCTCAAATTAAGCAAAGTACAAGAGGTAATTTTTGGCCTTGCCCTGTTGAATTCTTCCAGCTCAGATCTTAGAGGTTTCGCT GCCCAGTTTATCAAACAGAAGCTTCCAGATCTTCTGCGTTCTTACATTGACGCAGACGTCAGTGGAAATCAAGAAGGTGGCTTCCAAGAT ATAGCAATAGAGGTCCTACACCTCCTCCTCTCCCATCTCCTCTTTGGGCAGAAGGGAGCCTTTGGAGTTGGACAAGAACAGATAGACGCT TTTCTTAAGACGCTGCGCAGAGATTTTCCCCAAGAACGCTGTCCCGTGGTGCTCGCACCACTTTTATACCCTGAAAAACGGGACATTCTA ATGGACAGGATCCTGCCTGATTCCGGAGGGGTAGCTAAAACCATGATGGAGAGCTCTTTGGCTGATTTCATGCAAGAAGTAGGCTATGGC TTTTGTGCAAGTATTGAAGAATGTCGCAATATAATCGTGCAGTTTGGTGTTCGGGAGGTCACAGCTGCCCAGGTTGCAAGGGTTTTGGGA ATGATGGCTCGAACTCATTCAGGATTAACAGATGGCATTCCATTACAGAGTATTTCTGCTCCGGGCAGTGGGATCTGGAGTGATGGGAAA GATAAAAGTGATGGAGCACAGGCACACACATGGAATGTAGAAGTCTTGATTGACGTTCTTAAAGAACTGAATCCAAGTTTGAATTTCAAG GAAGTAACTTATGAACTGGACCATCCTGGATTTCAAATTCGTGACAGTAAAGGACTTCATAATGTGGTTTATGGCATTCAGAGGGGTTTG GGTATGGAAGTGTTCCCAGTAGACCTCATATATAGACCTTGGAAACATGCTGAAGGCCAGCTCTCCTTCATTCAACATTCCCTTATAAAT CCAGAGATCTTCTGTTTTGCTGACTATCCCTGTCATACTGTTGCCACTGATATTCTGAAAGCACCACCAGAGGATGACAATCGAGAAATT GCCACATGGAAGAGCTTGGATTTGATTGAATCTCTGCTGAGGCTTGCAGAGGTTGGGCAGTATGAGCAAGTCAAACAGCTCTTCAGCTTC CCTATCAAACACTGTCCAGACATGCTGGTATTGGCCTTACTACAAATTAACACCTCTTGGCATACCTTGCGCCATGAACTTATCTCCACT CTGATGCCAATTTTCCTTGGAAACCATCCTAACTCAGCTATTATTTTGCACTATGCATGGCATGGGCAGGGACAGTCTCCCTCAATTCGC CAACTTATCATGCATGCAATGGCAGAATGGTACATGAGAGGGGAGCAGTATGATCAGGCCAAATTGTCTCGAATACTTGATGTGGCCCAG GACTTGAAGGCCTTGTCAATGCTGCTAAATGGTACTCCATTTGCCTTTGTTATTGACCTTGCTGCACTTGCTTCACGTCGTGAATACCTC AAACTTGATAAGTGGCTCACAGATAAAATTCGAGAGCATGGGGAGCCTTTTATCCAGGCGTGTATGACTTTTTTAAAGAGACGGTGTCCT TCTATTTTGGGCGGACTTGCCCCAGAAAAAGACCAGCCCAAAAGTGCTCAACTTCCTCCAGAAACTTTGGCGACAATGTTGGCCTGTCTG CAAGCTTGTGCAGGCTCCTGGTGGACCCATGTGGAAATGGGACCTCCAGATCCCATTCTGGGAGTCACTGAAGCCTTTAAGAGGGACACC AATAGCAAAAAGATGAATCTGGGAGTTGGTGCCTACCGGGATGATAATGGAAAGCCTTACGTTCTGCCTAGCGTCCGCAAGGCAGAGGCC CAGATTGCCGCAAAAAATTTGGACAAGGAATACCTGCCCATTGGGGGACTGGCTGAATTTTGCAAGGCATCTGCAGAACTAGCCCTGGGT GAGAACAGCGAAGTCTTGAAGAGTGGCCGGTTTGTCACTGTGCAGACCATTTCTGGAACTGGAGCCTTAAGGATCGGAGCCAGTTTTCTG CAAAGATTTTTTAAGTTCAGCCGAGATGTCTTTCTGCCCAAACCAACCTGGGGAAACCACACACCCATCTTCAGGGATGCTGGCATGCAG CTACAAGGTTATCGGTATTATGACCCCAAGACTTGCGGTTTTGACTTCACAGGCGCTGTGGAGGATATTTCAAAAATACCAGAGCAGAGT GTTCTTCTTCTGCATGCCTGCGCCCACAATCCCACGGGAGTGGACCCGCGTCCGGAACAGTGGAAGGAAATAGCAACAGTGGTGAAGAAA AGGAATCTCTTTGCGTTCTTTGACATGGCCTACCAAGGCTTTGCCAGTGGTGATGGTGATAAGGATGCCTGGGCTGTGCGCCACTTCATC GAACAGGGCATTAATGTTTGCCTCTGCCAATCATATGCCAAGAACATGGGCTTATATGGTGAGCGTGTAGGAGCCTTCACTATGGTCTGC AAAGATGCGGATGAAGCCAAAAGGGTAGAGTCACAGTTGAAGATCTTGATCCGTCCCATGTATTCCAACCCTCCCCTCAATGGGGCCCGG ATTGCTGCTGCCATTCTGAACACCCCAGATTTGCGAAAACAATGGCTGCAAGAAGTGAAAGTCATGGCTGACCGCATCATTGGCATGCGG ACTCAACTGGTCTCCAACCTCAAGAAGGAGGGTTCCACCCACAATTGGCAACACATCACCGACCAAATTGGCATGTTCTGTTTCACAGGG CTAAAGCCTGAACAGGTGGAGCGGCTGATCAAGGAGTTCTCCATCTACATGACAAAAGATGGCCGCATCTCTGTGGCAGGGGTCACCTCC AGCAACGTGGGCTACCTTGCCCATGCCATTCACCAGGTCACCAAGTAATGTCCCTGGTGCGAGGAAACAGAGACAACCTTTCTGTCTTCA GCCTCTGCTATTGAGAGCTTCACACAGACAATGAGAGAGGGTGGATGGTGGTGAGTGGATCATTTCTTTCAGCCACAGTGTGTAACACTC AGCATTTGAATGTTTCTCAGAAAAGAACATGTAGTGACACAGGGCAGAGGCATCCATGGCTGGCGTCTGGAATATTAAACCAAACTCTCC CCGGTCCTTTTTTCTCCAACTTTTCTCAAAGAGTTTACATGTGCAAGAAAGTCATCGCACCAAAAAACCTGTCAATTATGCCATTGCAAT ATTTCAGAAGCTTTAACTGAAGTGTCAGGTTCCTCGTGAGAAACAGCACACGTTAGAGGCTTTGAGAGAAGGCCTAGTTCTGTCATGAGT AGTCGGCCTCGTGTCTGTCCTCCCATCTTGGAACAACCTTATCAACAGGCCGCACTGCAGAAATGATGTTTTATGAAAACCAATGAGGCT GCTGCCACTCCAGCAAGGGAAATAATGCAGTTTCCTGTCTTATTTAAGAAAAAGAGAAGGCTCTCTTTTCTCCCTTGTCATTGCCGTTCT TTTCCTTACACGCAAAGATTTTTTAACTATTGCAGATTTTCATCCCATTCTACTGCTTGATTGACCATCAACTCCATCCTATCGAGATTT ATTTAAGAATGAAGAACATAATTTTCTGCTGATGCTGTACCCTCACCCTTTTCAGCAAAGAATAGTGGAGAGTAGGAAACTGTACTTTAT CTCGGCATCCTCTTGAATGATAGTGCAAGTTTCTCCAGTTGGGATGTTGTCTCTGCCCGGTTGGACCTCCTCCCTTTGTTGAATGTGGTG TGCAGCCTCTCATCTCACACTGTGAGTCCAGCGGCGCAGGGTGGTACCAGGAAAGAGGATATTCTAGGCTTTGCGTGCTGCTAGCTGGGT TCAGGCTTCACCCACTGGAAAGAACCACCATCTGCTCTAACCATGTAGACTTATTGCGGCCTGGTTTCTCTGTTACAATAAAATTACTGT >17712_17712_3_CNOT1-GOT2_CNOT1_chr16_58608513_ENST00000441024_GOT2_chr16_58757806_ENST00000245206_length(amino acids)=1067AA_BP=667 MLPPQPAMNLDSLSLALSQISYLVDNLTKKNYRASQQEIQHIVNRHGPEADRHLLRCLFSHVDFSGDGKSSGKDFHQTQFLIQECALLIT KPNFISTLSYAIDNPLHYQKSLKPAPHLFAQLSKVLKLSKVQEVIFGLALLNSSSSDLRGFAAQFIKQKLPDLLRSYIDADVSGNQEGGF QDIAIEVLHLLLSHLLFGQKGAFGVGQEQIDAFLKTLRRDFPQERCPVVLAPLLYPEKRDILMDRILPDSGGVAKTMMESSLADFMQEVG YGFCASIEECRNIIVQFGVREVTAAQVARVLGMMARTHSGLTDGIPLQSISAPGSGIWSDGKDKSDGAQAHTWNVEVLIDVLKELNPSLN FKEVTYELDHPGFQIRDSKGLHNVVYGIQRGLGMEVFPVDLIYRPWKHAEGQLSFIQHSLINPEIFCFADYPCHTVATDILKAPPEDDNR EIATWKSLDLIESLLRLAEVGQYEQVKQLFSFPIKHCPDMLVLALLQINTSWHTLRHELISTLMPIFLGNHPNSAIILHYAWHGQGQSPS IRQLIMHAMAEWYMRGEQYDQAKLSRILDVAQDLKALSMLLNGTPFAFVIDLAALASRREYLKLDKWLTDKIREHGEPFIQACMTFLKRR CPSILGGLAPEKDQPKSAQLPPETLATMLACLQACAGSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKA EAQIAAKNLDKEYLPIGGLAEFCKASAELALGENSEVLKSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFLPKPTWGNHTPIFRDAG MQLQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDAWAVRH FIEQGINVCLCQSYAKNMGLYGERVGAFTMVCKDADEAKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLRKQWLQEVKVMADRIIG -------------------------------------------------------------- >17712_17712_4_CNOT1-GOT2_CNOT1_chr16_58608513_ENST00000441024_GOT2_chr16_58757806_ENST00000434819_length(transcript)=3692nt_BP=2264nt CGGCGCCATTTTGTAGAGAAACAAGCGGAGTTAACCGAAGAGGGGGTCGAGGAGAGCCGGAGTCGGGGACCCAGGAGTTTCCTGTGTCCA GCGCTGCCGGAGCCGCCTGAGGTGCCATGTTTCAGAACAGAGTAAGACCCCTGGTAAAGAAGAACTGAAGATATTATACAGATACCAGAT ATAGCCTAATTACAAAGAAAGCATTAACCTGCCTCTGAGGTGACTAAAGGGGAATAATGGTGATTTTGCGCCGGGCTCGGCCGCCTGCTT CCGCCCCAACCAGCAATGAATCTTGACTCGCTCTCGCTGGCCTTGTCTCAAATCAGCTACCTGGTGGACAATTTAACCAAGAAAAATTAC CGAGCCAGCCAGCAGGAAATACAGCATATTGTGAATCGGCACGGTCCTGAGGCAGACAGGCATTTATTACGCTGCCTATTTTCGCATGTG GATTTCAGTGGCGATGGTAAAAGCAGTGGCAAAGATTTCCATCAGACTCAGTTTCTGATTCAGGAGTGTGCGTTGCTGATTACAAAGCCA AATTTTATCTCGACGCTGTCCTATGCCATTGATAATCCATTGCACTATCAGAAGAGTTTAAAGCCTGCACCCCACTTATTTGCCCAGCTG AGTAAAGTGCTCAAATTAAGCAAAGTACAAGAGGTAATTTTTGGCCTTGCCCTGTTGAATTCTTCCAGCTCAGATCTTAGAGGTTTCGCT GCCCAGTTTATCAAACAGAAGCTTCCAGATCTTCTGCGTTCTTACATTGACGCAGACGTCAGTGGAAATCAAGAAGGTGGCTTCCAAGAT ATAGCAATAGAGGTCCTACACCTCCTCCTCTCCCATCTCCTCTTTGGGCAGAAGGGAGCCTTTGGAGTTGGACAAGAACAGATAGACGCT TTTCTTAAGACGCTGCGCAGAGATTTTCCCCAAGAACGCTGTCCCGTGGTGCTCGCACCACTTTTATACCCTGAAAAACGGGACATTCTA ATGGACAGGATCCTGCCTGATTCCGGAGGGGTAGCTAAAACCATGATGGAGAGCTCTTTGGCTGATTTCATGCAAGAAGTAGGCTATGGC TTTTGTGCAAGTATTGAAGAATGTCGCAATATAATCGTGCAGTTTGGTGTTCGGGAGGTCACAGCTGCCCAGGTTGCAAGGGTTTTGGGA ATGATGGCTCGAACTCATTCAGGATTAACAGATGGCATTCCATTACAGAGTATTTCTGCTCCGGGCAGTGGGATCTGGAGTGATGGGAAA GATAAAAGTGATGGAGCACAGGCACACACATGGAATGTAGAAGTCTTGATTGACGTTCTTAAAGAACTGAATCCAAGTTTGAATTTCAAG GAAGTAACTTATGAACTGGACCATCCTGGATTTCAAATTCGTGACAGTAAAGGACTTCATAATGTGGTTTATGGCATTCAGAGGGGTTTG GGTATGGAAGTGTTCCCAGTAGACCTCATATATAGACCTTGGAAACATGCTGAAGGCCAGCTCTCCTTCATTCAACATTCCCTTATAAAT CCAGAGATCTTCTGTTTTGCTGACTATCCCTGTCATACTGTTGCCACTGATATTCTGAAAGCACCACCAGAGGATGACAATCGAGAAATT GCCACATGGAAGAGCTTGGATTTGATTGAATCTCTGCTGAGGCTTGCAGAGGTTGGGCAGTATGAGCAAGTCAAACAGCTCTTCAGCTTC CCTATCAAACACTGTCCAGACATGCTGGTATTGGCCTTACTACAAATTAACACCTCTTGGCATACCTTGCGCCATGAACTTATCTCCACT CTGATGCCAATTTTCCTTGGAAACCATCCTAACTCAGCTATTATTTTGCACTATGCATGGCATGGGCAGGGACAGTCTCCCTCAATTCGC CAACTTATCATGCATGCAATGGCAGAATGGTACATGAGAGGGGAGCAGTATGATCAGGCCAAATTGTCTCGAATACTTGATGTGGCCCAG GACTTGAAGGCCTTGTCAATGCTGCTAAATGGTACTCCATTTGCCTTTGTTATTGACCTTGCTGCACTTGCTTCACGTCGTGAATACCTC AAACTTGATAAGTGGCTCACAGATAAAATTCGAGAGCATGGGGAGCCTTTTATCCAGGCGTGTATGACTTTTTTAAAGAGACGGTGTCCT TCTATTTTGGGCGGACTTGCCCCAGAAAAAGACCAGCCCAAAAGTGCTCAACTTCCTCCAGAAACTTTGGCGACAATGTTGGCCTGTCTG CAAGCTTGTGCAGGCTCCTGGTGGACCCATGTGGAAATGGGACCTCCAGATCCCATTCTGGGAGTCACTGAAGCCTTTAAGAGGGACACC AATAGCAAAAAGATGAATCTGGGAGTTGGTGCCTACCGGGATGATAATGGAAAGCCTTACGTTCTGCCTAGCGTCCGCAAGTTTGTCACT GTGCAGACCATTTCTGGAACTGGAGCCTTAAGGATCGGAGCCAGTTTTCTGCAAAGATTTTTTAAGTTCAGCCGAGATGTCTTTCTGCCC AAACCAACCTGGGGAAACCACACACCCATCTTCAGGGATGCTGGCATGCAGCTACAAGGTTATCGGTATTATGACCCCAAGACTTGCGGT TTTGACTTCACAGGCGCTGTGGAGGATATTTCAAAAATACCAGAGCAGAGTGTTCTTCTTCTGCATGCCTGCGCCCACAATCCCACGGGA GTGGACCCGCGTCCGGAACAGTGGAAGGAAATAGCAACAGTGGTGAAGAAAAGGAATCTCTTTGCGTTCTTTGACATGGCCTACCAAGGC TTTGCCAGTGGTGATGGTGATAAGGATGCCTGGGCTGTGCGCCACTTCATCGAACAGGGCATTAATGTTTGCCTCTGCCAATCATATGCC AAGAACATGGGCTTATATGGTGAGCGTGTAGGAGCCTTCACTATGGTCTGCAAAGATGCGGATGAAGCCAAAAGGGTAGAGTCACAGTTG AAGATCTTGATCCGTCCCATGTATTCCAACCCTCCCCTCAATGGGGCCCGGATTGCTGCTGCCATTCTGAACACCCCAGATTTGCGAAAA CAATGGCTGCAAGAAGTGAAAGTCATGGCTGACCGCATCATTGGCATGCGGACTCAACTGGTCTCCAACCTCAAGAAGGAGGGTTCCACC CACAATTGGCAACACATCACCGACCAAATTGGCATGTTCTGTTTCACAGGGCTAAAGCCTGAACAGGTGGAGCGGCTGATCAAGGAGTTC TCCATCTACATGACAAAAGATGGCCGCATCTCTGTGGCAGGGGTCACCTCCAGCAACGTGGGCTACCTTGCCCATGCCATTCACCAGGTC ACCAAGTAATGTCCCTGGTGCGAGGAAACAGAGACAACCTTTCTGTCTTCAGCCTCTGCTATTGAGAGCTTCACACAGACAATGAGAGAG GGTGGATGGTGGTGAGTGGATCATTTCTTTCAGCCACAGTGTGTAACACTCAGCATTTGAATGTTTCTCAGAAAAGAACATGTAGTGACA CAGGGCAGAGGCATCCATGGCTGGCGTCTGGAATATTAAACCAAACTCTCCCCGGTCCTTTTTTCTCCAACTTTTCTCAAAGAGTTTACA TGTGCAAGAAAGTCATCGCACCAAAAAACCTGTCAATTATGCCATTGCAATATTTCAGAAGCTTTAACTGAAGTGTCAGGTTCCTCGTGA >17712_17712_4_CNOT1-GOT2_CNOT1_chr16_58608513_ENST00000441024_GOT2_chr16_58757806_ENST00000434819_length(amino acids)=1024AA_BP=667 MLPPQPAMNLDSLSLALSQISYLVDNLTKKNYRASQQEIQHIVNRHGPEADRHLLRCLFSHVDFSGDGKSSGKDFHQTQFLIQECALLIT KPNFISTLSYAIDNPLHYQKSLKPAPHLFAQLSKVLKLSKVQEVIFGLALLNSSSSDLRGFAAQFIKQKLPDLLRSYIDADVSGNQEGGF QDIAIEVLHLLLSHLLFGQKGAFGVGQEQIDAFLKTLRRDFPQERCPVVLAPLLYPEKRDILMDRILPDSGGVAKTMMESSLADFMQEVG YGFCASIEECRNIIVQFGVREVTAAQVARVLGMMARTHSGLTDGIPLQSISAPGSGIWSDGKDKSDGAQAHTWNVEVLIDVLKELNPSLN FKEVTYELDHPGFQIRDSKGLHNVVYGIQRGLGMEVFPVDLIYRPWKHAEGQLSFIQHSLINPEIFCFADYPCHTVATDILKAPPEDDNR EIATWKSLDLIESLLRLAEVGQYEQVKQLFSFPIKHCPDMLVLALLQINTSWHTLRHELISTLMPIFLGNHPNSAIILHYAWHGQGQSPS IRQLIMHAMAEWYMRGEQYDQAKLSRILDVAQDLKALSMLLNGTPFAFVIDLAALASRREYLKLDKWLTDKIREHGEPFIQACMTFLKRR CPSILGGLAPEKDQPKSAQLPPETLATMLACLQACAGSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKF VTVQTISGTGALRIGASFLQRFFKFSRDVFLPKPTWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNP TGVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTMVCKDADEAKRVES QLKILIRPMYSNPPLNGARIAAAILNTPDLRKQWLQEVKVMADRIIGMRTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIK -------------------------------------------------------------- >17712_17712_5_CNOT1-GOT2_CNOT1_chr16_58608513_ENST00000569240_GOT2_chr16_58757806_ENST00000245206_length(transcript)=4504nt_BP=2260nt GCCATTTTGTAGAGAAACAAGCGGAGTTAACCGAAGAGGGGGTCGAGGAGAGCCGGAGTCGGGGACCCAGGAGTTTCCTGTGTCCAGCGC TGCCGGAGCCGCCTGAGGTGCCATGTTTCAGAACAGAGTAAGACCCCTGGTAAAGAAGAACTGAAGATATTATACAGATACCAGATATAG CCTAATTACAAAGAAAGCATTAACCTGCCTCTGAGGTGACTAAAGGGGAATAATGGTGATTTTGCGCCGGGCTCGGCCGCCTGCTTCCGC CCCAACCAGCAATGAATCTTGACTCGCTCTCGCTGGCCTTGTCTCAAATCAGCTACCTGGTGGACAATTTAACCAAGAAAAATTACCGAG CCAGCCAGCAGGAAATACAGCATATTGTGAATCGGCACGGTCCTGAGGCAGACAGGCATTTATTACGCTGCCTATTTTCGCATGTGGATT TCAGTGGCGATGGTAAAAGCAGTGGCAAAGATTTCCATCAGACTCAGTTTCTGATTCAGGAGTGTGCGTTGCTGATTACAAAGCCAAATT TTATCTCGACGCTGTCCTATGCCATTGATAATCCATTGCACTATCAGAAGAGTTTAAAGCCTGCACCCCACTTATTTGCCCAGCTGAGTA AAGTGCTCAAATTAAGCAAAGTACAAGAGGTAATTTTTGGCCTTGCCCTGTTGAATTCTTCCAGCTCAGATCTTAGAGGTTTCGCTGCCC AGTTTATCAAACAGAAGCTTCCAGATCTTCTGCGTTCTTACATTGACGCAGACGTCAGTGGAAATCAAGAAGGTGGCTTCCAAGATATAG CAATAGAGGTCCTACACCTCCTCCTCTCCCATCTCCTCTTTGGGCAGAAGGGAGCCTTTGGAGTTGGACAAGAACAGATAGACGCTTTTC TTAAGACGCTGCGCAGAGATTTTCCCCAAGAACGCTGTCCCGTGGTGCTCGCACCACTTTTATACCCTGAAAAACGGGACATTCTAATGG ACAGGATCCTGCCTGATTCCGGAGGGGTAGCTAAAACCATGATGGAGAGCTCTTTGGCTGATTTCATGCAAGAAGTAGGCTATGGCTTTT GTGCAAGTATTGAAGAATGTCGCAATATAATCGTGCAGTTTGGTGTTCGGGAGGTCACAGCTGCCCAGGTTGCAAGGGTTTTGGGAATGA TGGCTCGAACTCATTCAGGATTAACAGATGGCATTCCATTACAGAGTATTTCTGCTCCGGGCAGTGGGATCTGGAGTGATGGGAAAGATA AAAGTGATGGAGCACAGGCACACACATGGAATGTAGAAGTCTTGATTGACGTTCTTAAAGAACTGAATCCAAGTTTGAATTTCAAGGAAG TAACTTATGAACTGGACCATCCTGGATTTCAAATTCGTGACAGTAAAGGACTTCATAATGTGGTTTATGGCATTCAGAGGGGTTTGGGTA TGGAAGTGTTCCCAGTAGACCTCATATATAGACCTTGGAAACATGCTGAAGGCCAGCTCTCCTTCATTCAACATTCCCTTATAAATCCAG AGATCTTCTGTTTTGCTGACTATCCCTGTCATACTGTTGCCACTGATATTCTGAAAGCACCACCAGAGGATGACAATCGAGAAATTGCCA CATGGAAGAGCTTGGATTTGATTGAATCTCTGCTGAGGCTTGCAGAGGTTGGGCAGTATGAGCAAGTCAAACAGCTCTTCAGCTTCCCTA TCAAACACTGTCCAGACATGCTGGTATTGGCCTTACTACAAATTAACACCTCTTGGCATACCTTGCGCCATGAACTTATCTCCACTCTGA TGCCAATTTTCCTTGGAAACCATCCTAACTCAGCTATTATTTTGCACTATGCATGGCATGGGCAGGGACAGTCTCCCTCAATTCGCCAAC TTATCATGCATGCAATGGCAGAATGGTACATGAGAGGGGAGCAGTATGATCAGGCCAAATTGTCTCGAATACTTGATGTGGCCCAGGACT TGAAGGCCTTGTCAATGCTGCTAAATGGTACTCCATTTGCCTTTGTTATTGACCTTGCTGCACTTGCTTCACGTCGTGAATACCTCAAAC TTGATAAGTGGCTCACAGATAAAATTCGAGAGCATGGGGAGCCTTTTATCCAGGCGTGTATGACTTTTTTAAAGAGACGGTGTCCTTCTA TTTTGGGCGGACTTGCCCCAGAAAAAGACCAGCCCAAAAGTGCTCAACTTCCTCCAGAAACTTTGGCGACAATGTTGGCCTGTCTGCAAG CTTGTGCAGGCTCCTGGTGGACCCATGTGGAAATGGGACCTCCAGATCCCATTCTGGGAGTCACTGAAGCCTTTAAGAGGGACACCAATA GCAAAAAGATGAATCTGGGAGTTGGTGCCTACCGGGATGATAATGGAAAGCCTTACGTTCTGCCTAGCGTCCGCAAGGCAGAGGCCCAGA TTGCCGCAAAAAATTTGGACAAGGAATACCTGCCCATTGGGGGACTGGCTGAATTTTGCAAGGCATCTGCAGAACTAGCCCTGGGTGAGA ACAGCGAAGTCTTGAAGAGTGGCCGGTTTGTCACTGTGCAGACCATTTCTGGAACTGGAGCCTTAAGGATCGGAGCCAGTTTTCTGCAAA GATTTTTTAAGTTCAGCCGAGATGTCTTTCTGCCCAAACCAACCTGGGGAAACCACACACCCATCTTCAGGGATGCTGGCATGCAGCTAC AAGGTTATCGGTATTATGACCCCAAGACTTGCGGTTTTGACTTCACAGGCGCTGTGGAGGATATTTCAAAAATACCAGAGCAGAGTGTTC TTCTTCTGCATGCCTGCGCCCACAATCCCACGGGAGTGGACCCGCGTCCGGAACAGTGGAAGGAAATAGCAACAGTGGTGAAGAAAAGGA ATCTCTTTGCGTTCTTTGACATGGCCTACCAAGGCTTTGCCAGTGGTGATGGTGATAAGGATGCCTGGGCTGTGCGCCACTTCATCGAAC AGGGCATTAATGTTTGCCTCTGCCAATCATATGCCAAGAACATGGGCTTATATGGTGAGCGTGTAGGAGCCTTCACTATGGTCTGCAAAG ATGCGGATGAAGCCAAAAGGGTAGAGTCACAGTTGAAGATCTTGATCCGTCCCATGTATTCCAACCCTCCCCTCAATGGGGCCCGGATTG CTGCTGCCATTCTGAACACCCCAGATTTGCGAAAACAATGGCTGCAAGAAGTGAAAGTCATGGCTGACCGCATCATTGGCATGCGGACTC AACTGGTCTCCAACCTCAAGAAGGAGGGTTCCACCCACAATTGGCAACACATCACCGACCAAATTGGCATGTTCTGTTTCACAGGGCTAA AGCCTGAACAGGTGGAGCGGCTGATCAAGGAGTTCTCCATCTACATGACAAAAGATGGCCGCATCTCTGTGGCAGGGGTCACCTCCAGCA ACGTGGGCTACCTTGCCCATGCCATTCACCAGGTCACCAAGTAATGTCCCTGGTGCGAGGAAACAGAGACAACCTTTCTGTCTTCAGCCT CTGCTATTGAGAGCTTCACACAGACAATGAGAGAGGGTGGATGGTGGTGAGTGGATCATTTCTTTCAGCCACAGTGTGTAACACTCAGCA TTTGAATGTTTCTCAGAAAAGAACATGTAGTGACACAGGGCAGAGGCATCCATGGCTGGCGTCTGGAATATTAAACCAAACTCTCCCCGG TCCTTTTTTCTCCAACTTTTCTCAAAGAGTTTACATGTGCAAGAAAGTCATCGCACCAAAAAACCTGTCAATTATGCCATTGCAATATTT CAGAAGCTTTAACTGAAGTGTCAGGTTCCTCGTGAGAAACAGCACACGTTAGAGGCTTTGAGAGAAGGCCTAGTTCTGTCATGAGTAGTC GGCCTCGTGTCTGTCCTCCCATCTTGGAACAACCTTATCAACAGGCCGCACTGCAGAAATGATGTTTTATGAAAACCAATGAGGCTGCTG CCACTCCAGCAAGGGAAATAATGCAGTTTCCTGTCTTATTTAAGAAAAAGAGAAGGCTCTCTTTTCTCCCTTGTCATTGCCGTTCTTTTC CTTACACGCAAAGATTTTTTAACTATTGCAGATTTTCATCCCATTCTACTGCTTGATTGACCATCAACTCCATCCTATCGAGATTTATTT AAGAATGAAGAACATAATTTTCTGCTGATGCTGTACCCTCACCCTTTTCAGCAAAGAATAGTGGAGAGTAGGAAACTGTACTTTATCTCG GCATCCTCTTGAATGATAGTGCAAGTTTCTCCAGTTGGGATGTTGTCTCTGCCCGGTTGGACCTCCTCCCTTTGTTGAATGTGGTGTGCA GCCTCTCATCTCACACTGTGAGTCCAGCGGCGCAGGGTGGTACCAGGAAAGAGGATATTCTAGGCTTTGCGTGCTGCTAGCTGGGTTCAG GCTTCACCCACTGGAAAGAACCACCATCTGCTCTAACCATGTAGACTTATTGCGGCCTGGTTTCTCTGTTACAATAAAATTACTGTAGAC >17712_17712_5_CNOT1-GOT2_CNOT1_chr16_58608513_ENST00000569240_GOT2_chr16_58757806_ENST00000245206_length(amino acids)=1067AA_BP=667 MLPPQPAMNLDSLSLALSQISYLVDNLTKKNYRASQQEIQHIVNRHGPEADRHLLRCLFSHVDFSGDGKSSGKDFHQTQFLIQECALLIT KPNFISTLSYAIDNPLHYQKSLKPAPHLFAQLSKVLKLSKVQEVIFGLALLNSSSSDLRGFAAQFIKQKLPDLLRSYIDADVSGNQEGGF QDIAIEVLHLLLSHLLFGQKGAFGVGQEQIDAFLKTLRRDFPQERCPVVLAPLLYPEKRDILMDRILPDSGGVAKTMMESSLADFMQEVG YGFCASIEECRNIIVQFGVREVTAAQVARVLGMMARTHSGLTDGIPLQSISAPGSGIWSDGKDKSDGAQAHTWNVEVLIDVLKELNPSLN FKEVTYELDHPGFQIRDSKGLHNVVYGIQRGLGMEVFPVDLIYRPWKHAEGQLSFIQHSLINPEIFCFADYPCHTVATDILKAPPEDDNR EIATWKSLDLIESLLRLAEVGQYEQVKQLFSFPIKHCPDMLVLALLQINTSWHTLRHELISTLMPIFLGNHPNSAIILHYAWHGQGQSPS IRQLIMHAMAEWYMRGEQYDQAKLSRILDVAQDLKALSMLLNGTPFAFVIDLAALASRREYLKLDKWLTDKIREHGEPFIQACMTFLKRR CPSILGGLAPEKDQPKSAQLPPETLATMLACLQACAGSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKA EAQIAAKNLDKEYLPIGGLAEFCKASAELALGENSEVLKSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFLPKPTWGNHTPIFRDAG MQLQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDAWAVRH FIEQGINVCLCQSYAKNMGLYGERVGAFTMVCKDADEAKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLRKQWLQEVKVMADRIIG -------------------------------------------------------------- >17712_17712_6_CNOT1-GOT2_CNOT1_chr16_58608513_ENST00000569240_GOT2_chr16_58757806_ENST00000434819_length(transcript)=3688nt_BP=2260nt GCCATTTTGTAGAGAAACAAGCGGAGTTAACCGAAGAGGGGGTCGAGGAGAGCCGGAGTCGGGGACCCAGGAGTTTCCTGTGTCCAGCGC TGCCGGAGCCGCCTGAGGTGCCATGTTTCAGAACAGAGTAAGACCCCTGGTAAAGAAGAACTGAAGATATTATACAGATACCAGATATAG CCTAATTACAAAGAAAGCATTAACCTGCCTCTGAGGTGACTAAAGGGGAATAATGGTGATTTTGCGCCGGGCTCGGCCGCCTGCTTCCGC CCCAACCAGCAATGAATCTTGACTCGCTCTCGCTGGCCTTGTCTCAAATCAGCTACCTGGTGGACAATTTAACCAAGAAAAATTACCGAG CCAGCCAGCAGGAAATACAGCATATTGTGAATCGGCACGGTCCTGAGGCAGACAGGCATTTATTACGCTGCCTATTTTCGCATGTGGATT TCAGTGGCGATGGTAAAAGCAGTGGCAAAGATTTCCATCAGACTCAGTTTCTGATTCAGGAGTGTGCGTTGCTGATTACAAAGCCAAATT TTATCTCGACGCTGTCCTATGCCATTGATAATCCATTGCACTATCAGAAGAGTTTAAAGCCTGCACCCCACTTATTTGCCCAGCTGAGTA AAGTGCTCAAATTAAGCAAAGTACAAGAGGTAATTTTTGGCCTTGCCCTGTTGAATTCTTCCAGCTCAGATCTTAGAGGTTTCGCTGCCC AGTTTATCAAACAGAAGCTTCCAGATCTTCTGCGTTCTTACATTGACGCAGACGTCAGTGGAAATCAAGAAGGTGGCTTCCAAGATATAG CAATAGAGGTCCTACACCTCCTCCTCTCCCATCTCCTCTTTGGGCAGAAGGGAGCCTTTGGAGTTGGACAAGAACAGATAGACGCTTTTC TTAAGACGCTGCGCAGAGATTTTCCCCAAGAACGCTGTCCCGTGGTGCTCGCACCACTTTTATACCCTGAAAAACGGGACATTCTAATGG ACAGGATCCTGCCTGATTCCGGAGGGGTAGCTAAAACCATGATGGAGAGCTCTTTGGCTGATTTCATGCAAGAAGTAGGCTATGGCTTTT GTGCAAGTATTGAAGAATGTCGCAATATAATCGTGCAGTTTGGTGTTCGGGAGGTCACAGCTGCCCAGGTTGCAAGGGTTTTGGGAATGA TGGCTCGAACTCATTCAGGATTAACAGATGGCATTCCATTACAGAGTATTTCTGCTCCGGGCAGTGGGATCTGGAGTGATGGGAAAGATA AAAGTGATGGAGCACAGGCACACACATGGAATGTAGAAGTCTTGATTGACGTTCTTAAAGAACTGAATCCAAGTTTGAATTTCAAGGAAG TAACTTATGAACTGGACCATCCTGGATTTCAAATTCGTGACAGTAAAGGACTTCATAATGTGGTTTATGGCATTCAGAGGGGTTTGGGTA TGGAAGTGTTCCCAGTAGACCTCATATATAGACCTTGGAAACATGCTGAAGGCCAGCTCTCCTTCATTCAACATTCCCTTATAAATCCAG AGATCTTCTGTTTTGCTGACTATCCCTGTCATACTGTTGCCACTGATATTCTGAAAGCACCACCAGAGGATGACAATCGAGAAATTGCCA CATGGAAGAGCTTGGATTTGATTGAATCTCTGCTGAGGCTTGCAGAGGTTGGGCAGTATGAGCAAGTCAAACAGCTCTTCAGCTTCCCTA TCAAACACTGTCCAGACATGCTGGTATTGGCCTTACTACAAATTAACACCTCTTGGCATACCTTGCGCCATGAACTTATCTCCACTCTGA TGCCAATTTTCCTTGGAAACCATCCTAACTCAGCTATTATTTTGCACTATGCATGGCATGGGCAGGGACAGTCTCCCTCAATTCGCCAAC TTATCATGCATGCAATGGCAGAATGGTACATGAGAGGGGAGCAGTATGATCAGGCCAAATTGTCTCGAATACTTGATGTGGCCCAGGACT TGAAGGCCTTGTCAATGCTGCTAAATGGTACTCCATTTGCCTTTGTTATTGACCTTGCTGCACTTGCTTCACGTCGTGAATACCTCAAAC TTGATAAGTGGCTCACAGATAAAATTCGAGAGCATGGGGAGCCTTTTATCCAGGCGTGTATGACTTTTTTAAAGAGACGGTGTCCTTCTA TTTTGGGCGGACTTGCCCCAGAAAAAGACCAGCCCAAAAGTGCTCAACTTCCTCCAGAAACTTTGGCGACAATGTTGGCCTGTCTGCAAG CTTGTGCAGGCTCCTGGTGGACCCATGTGGAAATGGGACCTCCAGATCCCATTCTGGGAGTCACTGAAGCCTTTAAGAGGGACACCAATA GCAAAAAGATGAATCTGGGAGTTGGTGCCTACCGGGATGATAATGGAAAGCCTTACGTTCTGCCTAGCGTCCGCAAGTTTGTCACTGTGC AGACCATTTCTGGAACTGGAGCCTTAAGGATCGGAGCCAGTTTTCTGCAAAGATTTTTTAAGTTCAGCCGAGATGTCTTTCTGCCCAAAC CAACCTGGGGAAACCACACACCCATCTTCAGGGATGCTGGCATGCAGCTACAAGGTTATCGGTATTATGACCCCAAGACTTGCGGTTTTG ACTTCACAGGCGCTGTGGAGGATATTTCAAAAATACCAGAGCAGAGTGTTCTTCTTCTGCATGCCTGCGCCCACAATCCCACGGGAGTGG ACCCGCGTCCGGAACAGTGGAAGGAAATAGCAACAGTGGTGAAGAAAAGGAATCTCTTTGCGTTCTTTGACATGGCCTACCAAGGCTTTG CCAGTGGTGATGGTGATAAGGATGCCTGGGCTGTGCGCCACTTCATCGAACAGGGCATTAATGTTTGCCTCTGCCAATCATATGCCAAGA ACATGGGCTTATATGGTGAGCGTGTAGGAGCCTTCACTATGGTCTGCAAAGATGCGGATGAAGCCAAAAGGGTAGAGTCACAGTTGAAGA TCTTGATCCGTCCCATGTATTCCAACCCTCCCCTCAATGGGGCCCGGATTGCTGCTGCCATTCTGAACACCCCAGATTTGCGAAAACAAT GGCTGCAAGAAGTGAAAGTCATGGCTGACCGCATCATTGGCATGCGGACTCAACTGGTCTCCAACCTCAAGAAGGAGGGTTCCACCCACA ATTGGCAACACATCACCGACCAAATTGGCATGTTCTGTTTCACAGGGCTAAAGCCTGAACAGGTGGAGCGGCTGATCAAGGAGTTCTCCA TCTACATGACAAAAGATGGCCGCATCTCTGTGGCAGGGGTCACCTCCAGCAACGTGGGCTACCTTGCCCATGCCATTCACCAGGTCACCA AGTAATGTCCCTGGTGCGAGGAAACAGAGACAACCTTTCTGTCTTCAGCCTCTGCTATTGAGAGCTTCACACAGACAATGAGAGAGGGTG GATGGTGGTGAGTGGATCATTTCTTTCAGCCACAGTGTGTAACACTCAGCATTTGAATGTTTCTCAGAAAAGAACATGTAGTGACACAGG GCAGAGGCATCCATGGCTGGCGTCTGGAATATTAAACCAAACTCTCCCCGGTCCTTTTTTCTCCAACTTTTCTCAAAGAGTTTACATGTG >17712_17712_6_CNOT1-GOT2_CNOT1_chr16_58608513_ENST00000569240_GOT2_chr16_58757806_ENST00000434819_length(amino acids)=1024AA_BP=667 MLPPQPAMNLDSLSLALSQISYLVDNLTKKNYRASQQEIQHIVNRHGPEADRHLLRCLFSHVDFSGDGKSSGKDFHQTQFLIQECALLIT KPNFISTLSYAIDNPLHYQKSLKPAPHLFAQLSKVLKLSKVQEVIFGLALLNSSSSDLRGFAAQFIKQKLPDLLRSYIDADVSGNQEGGF QDIAIEVLHLLLSHLLFGQKGAFGVGQEQIDAFLKTLRRDFPQERCPVVLAPLLYPEKRDILMDRILPDSGGVAKTMMESSLADFMQEVG YGFCASIEECRNIIVQFGVREVTAAQVARVLGMMARTHSGLTDGIPLQSISAPGSGIWSDGKDKSDGAQAHTWNVEVLIDVLKELNPSLN FKEVTYELDHPGFQIRDSKGLHNVVYGIQRGLGMEVFPVDLIYRPWKHAEGQLSFIQHSLINPEIFCFADYPCHTVATDILKAPPEDDNR EIATWKSLDLIESLLRLAEVGQYEQVKQLFSFPIKHCPDMLVLALLQINTSWHTLRHELISTLMPIFLGNHPNSAIILHYAWHGQGQSPS IRQLIMHAMAEWYMRGEQYDQAKLSRILDVAQDLKALSMLLNGTPFAFVIDLAALASRREYLKLDKWLTDKIREHGEPFIQACMTFLKRR CPSILGGLAPEKDQPKSAQLPPETLATMLACLQACAGSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKF VTVQTISGTGALRIGASFLQRFFKFSRDVFLPKPTWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNP TGVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTMVCKDADEAKRVES QLKILIRPMYSNPPLNGARIAAAILNTPDLRKQWLQEVKVMADRIIGMRTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIK -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for CNOT1-GOT2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000317147 | - | 16 | 49 | 1090_1605 | 659.6666666666666 | 2377.0 | CNOT6%2C CNOT6L%2C CNOT7 and CNOT8 |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000441024 | - | 16 | 31 | 1090_1605 | 659.6666666666666 | 1552.0 | CNOT6%2C CNOT6L%2C CNOT7 and CNOT8 |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000569240 | - | 16 | 49 | 1090_1605 | 659.6666666666666 | 2372.0 | CNOT6%2C CNOT6L%2C CNOT7 and CNOT8 |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000317147 | - | 16 | 49 | 800_1015 | 659.6666666666666 | 2377.0 | ZFP36 |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000441024 | - | 16 | 31 | 800_1015 | 659.6666666666666 | 1552.0 | ZFP36 |
| Hgene | CNOT1 | chr16:58608513 | chr16:58757806 | ENST00000569240 | - | 16 | 49 | 800_1015 | 659.6666666666666 | 2372.0 | ZFP36 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for CNOT1-GOT2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for CNOT1-GOT2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CNOT1 | C0557874 | Global developmental delay | 1 | GENOMICS_ENGLAND |
| Tgene | C0015544 | Failure to Thrive | 1 | GENOMICS_ENGLAND | |
| Tgene | C0025958 | Microcephaly | 1 | GENOMICS_ENGLAND | |
| Tgene | C0036572 | Seizures | 1 | GENOMICS_ENGLAND | |
| Tgene | C0220994 | Hyperammonemia | 1 | GENOMICS_ENGLAND | |
| Tgene | C0232466 | Feeding difficulties | 1 | GENOMICS_ENGLAND | |
| Tgene | C0557874 | Global developmental delay | 1 | GENOMICS_ENGLAND | |
| Tgene | C1836440 | Increased serum lactate | 1 | GENOMICS_ENGLAND | |
| Tgene | C3714756 | Intellectual Disability | 1 | GENOMICS_ENGLAND | |
| Tgene | C4022810 | Abnormality of nervous system morphology | 1 | GENOMICS_ENGLAND |
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