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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:LRCH1-PHF11 (FusionGDB2 ID:HG23143TG51131)

Fusion Gene Summary for LRCH1-PHF11

check button Fusion gene summary
Fusion gene informationFusion gene name: LRCH1-PHF11
Fusion gene ID: hg23143tg51131
HgeneTgene
Gene symbol

LRCH1

PHF11

Gene ID

23143

51131

Gene nameleucine rich repeats and calponin homology domain containing 1PHD finger protein 11
SynonymsCHDC1|NP81APY|BCAP|IGEL|IGER|IGHER|NY-REN-34|NYREN34
Cytomap('LRCH1')('PHF11')

13q14.13-q14.2

13q14.2

Type of geneprotein-codingprotein-coding
Descriptionleucine-rich repeat and calponin homology domain-containing protein 1leucine-rich repeats and calponin homology (CH) domain containing 1neuronal protein 81PHD finger protein 11BRCA1 C-terminus-associated proteinIgE responsiveness (atopic)renal carcinoma antigen NY-REN-34
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000311191, ENST00000389797, 
ENST00000389798, 
Fusion gene scores* DoF score12 X 7 X 5=4204 X 5 X 3=60
# samples 138
** MAII scorelog2(13/420*10)=-1.69187770463767
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/60*10)=0.415037499278844
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: LRCH1 [Title/Abstract] AND PHF11 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLRCH1(47303119)-PHF11(50087195), # samples:1
LRCH1(47303119)-PHF11(50080771), # samples:1
Anticipated loss of major functional domain due to fusion event.LRCH1-PHF11 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
LRCH1-PHF11 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
LRCH1-PHF11 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
LRCH1-PHF11 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
LRCH1-PHF11 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneLRCH1

GO:0034260

negative regulation of GTPase activity

28028151


check buttonFusion gene breakpoints across LRCH1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across PHF11 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-4Z-AA80-01ALRCH1chr13

47303119

-PHF11chr13

50080771

+
ChimerDB4BLCATCGA-4Z-AA80-01ALRCH1chr13

47303119

+PHF11chr13

50087195

+


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Fusion Gene ORF analysis for LRCH1-PHF11

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000311191ENST00000357596LRCH1chr13

47303119

-PHF11chr13

50080771

+
5CDS-5UTRENST00000311191ENST00000488958LRCH1chr13

47303119

-PHF11chr13

50080771

+
5CDS-5UTRENST00000389797ENST00000357596LRCH1chr13

47303119

-PHF11chr13

50080771

+
5CDS-5UTRENST00000389797ENST00000488958LRCH1chr13

47303119

-PHF11chr13

50080771

+
5CDS-5UTRENST00000389798ENST00000357596LRCH1chr13

47303119

-PHF11chr13

50080771

+
5CDS-5UTRENST00000389798ENST00000488958LRCH1chr13

47303119

-PHF11chr13

50080771

+
5CDS-intronENST00000311191ENST00000460489LRCH1chr13

47303119

-PHF11chr13

50080771

+
5CDS-intronENST00000311191ENST00000460489LRCH1chr13

47303119

+PHF11chr13

50087195

+
5CDS-intronENST00000389797ENST00000460489LRCH1chr13

47303119

-PHF11chr13

50080771

+
5CDS-intronENST00000389797ENST00000460489LRCH1chr13

47303119

+PHF11chr13

50087195

+
5CDS-intronENST00000389798ENST00000460489LRCH1chr13

47303119

-PHF11chr13

50080771

+
5CDS-intronENST00000389798ENST00000460489LRCH1chr13

47303119

+PHF11chr13

50087195

+
Frame-shiftENST00000311191ENST00000378319LRCH1chr13

47303119

-PHF11chr13

50080771

+
Frame-shiftENST00000389797ENST00000378319LRCH1chr13

47303119

-PHF11chr13

50080771

+
Frame-shiftENST00000389798ENST00000378319LRCH1chr13

47303119

-PHF11chr13

50080771

+
In-frameENST00000311191ENST00000357596LRCH1chr13

47303119

+PHF11chr13

50087195

+
In-frameENST00000311191ENST00000378319LRCH1chr13

47303119

+PHF11chr13

50087195

+
In-frameENST00000311191ENST00000488958LRCH1chr13

47303119

+PHF11chr13

50087195

+
In-frameENST00000389797ENST00000357596LRCH1chr13

47303119

+PHF11chr13

50087195

+
In-frameENST00000389797ENST00000378319LRCH1chr13

47303119

+PHF11chr13

50087195

+
In-frameENST00000389797ENST00000488958LRCH1chr13

47303119

+PHF11chr13

50087195

+
In-frameENST00000389798ENST00000357596LRCH1chr13

47303119

+PHF11chr13

50087195

+
In-frameENST00000389798ENST00000378319LRCH1chr13

47303119

+PHF11chr13

50087195

+
In-frameENST00000389798ENST00000488958LRCH1chr13

47303119

+PHF11chr13

50087195

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000311191LRCH1chr1347303119+ENST00000378319PHF11chr1350087195+323321311512910919
ENST00000311191LRCH1chr1347303119+ENST00000357596PHF11chr1350087195+322721311512910919
ENST00000311191LRCH1chr1347303119+ENST00000488958PHF11chr1350087195+322221311512910919
ENST00000389798LRCH1chr1347303119+ENST00000378319PHF11chr1350087195+320120991192878919
ENST00000389798LRCH1chr1347303119+ENST00000357596PHF11chr1350087195+319520991192878919
ENST00000389798LRCH1chr1347303119+ENST00000488958PHF11chr1350087195+319020991192878919
ENST00000389797LRCH1chr1347303119+ENST00000378319PHF11chr1350087195+32462144592923954
ENST00000389797LRCH1chr1347303119+ENST00000357596PHF11chr1350087195+32402144592923954
ENST00000389797LRCH1chr1347303119+ENST00000488958PHF11chr1350087195+32352144592923954

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000311191ENST00000378319LRCH1chr1347303119+PHF11chr1350087195+0.0008899580.99911004
ENST00000311191ENST00000357596LRCH1chr1347303119+PHF11chr1350087195+0.0009145080.99908555
ENST00000311191ENST00000488958LRCH1chr1347303119+PHF11chr1350087195+0.0009557770.99904424
ENST00000389798ENST00000378319LRCH1chr1347303119+PHF11chr1350087195+0.0009237790.99907625
ENST00000389798ENST00000357596LRCH1chr1347303119+PHF11chr1350087195+0.0009495850.99905044
ENST00000389798ENST00000488958LRCH1chr1347303119+PHF11chr1350087195+0.0009929330.99900705
ENST00000389797ENST00000378319LRCH1chr1347303119+PHF11chr1350087195+0.0005849560.99941504
ENST00000389797ENST00000357596LRCH1chr1347303119+PHF11chr1350087195+0.0006022780.99939775
ENST00000389797ENST00000488958LRCH1chr1347303119+PHF11chr1350087195+0.0006320030.999368

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Fusion Genomic Features for LRCH1-PHF11


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
LRCH1chr1347303119+PHF11chr1350087194+1.36E-081
LRCH1chr1347303119+PHF11chr1350087194+1.36E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for LRCH1-PHF11


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:47303119/chr13:50087195)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLRCH1chr13:47303119chr13:50087195ENST00000311191+171921_36634697.0Compositional biasNote=His-rich
HgeneLRCH1chr13:47303119chr13:50087195ENST00000311191+171937_54634697.0Compositional biasNote=Gly-rich
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389797+182021_36669764.0Compositional biasNote=His-rich
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389797+182037_54669764.0Compositional biasNote=Gly-rich
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389798+171921_36634729.0Compositional biasNote=His-rich
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389798+171937_54634729.0Compositional biasNote=Gly-rich
HgeneLRCH1chr13:47303119chr13:50087195ENST00000311191+1719121_143634697.0RepeatNote=LRR 2
HgeneLRCH1chr13:47303119chr13:50087195ENST00000311191+1719144_166634697.0RepeatNote=LRR 3
HgeneLRCH1chr13:47303119chr13:50087195ENST00000311191+1719167_187634697.0RepeatNote=LRR 4
HgeneLRCH1chr13:47303119chr13:50087195ENST00000311191+1719189_210634697.0RepeatNote=LRR 5
HgeneLRCH1chr13:47303119chr13:50087195ENST00000311191+1719212_234634697.0RepeatNote=LRR 6
HgeneLRCH1chr13:47303119chr13:50087195ENST00000311191+1719235_255634697.0RepeatNote=LRR 7
HgeneLRCH1chr13:47303119chr13:50087195ENST00000311191+1719257_278634697.0RepeatNote=LRR 8
HgeneLRCH1chr13:47303119chr13:50087195ENST00000311191+1719283_304634697.0RepeatNote=LRR 9
HgeneLRCH1chr13:47303119chr13:50087195ENST00000311191+171998_119634697.0RepeatNote=LRR 1
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389797+1820121_143669764.0RepeatNote=LRR 2
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389797+1820144_166669764.0RepeatNote=LRR 3
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389797+1820167_187669764.0RepeatNote=LRR 4
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389797+1820189_210669764.0RepeatNote=LRR 5
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389797+1820212_234669764.0RepeatNote=LRR 6
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389797+1820235_255669764.0RepeatNote=LRR 7
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389797+1820257_278669764.0RepeatNote=LRR 8
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389797+1820283_304669764.0RepeatNote=LRR 9
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389797+182098_119669764.0RepeatNote=LRR 1
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389798+1719121_143634729.0RepeatNote=LRR 2
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389798+1719144_166634729.0RepeatNote=LRR 3
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389798+1719167_187634729.0RepeatNote=LRR 4
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389798+1719189_210634729.0RepeatNote=LRR 5
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389798+1719212_234634729.0RepeatNote=LRR 6
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389798+1719235_255634729.0RepeatNote=LRR 7
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389798+1719257_278634729.0RepeatNote=LRR 8
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389798+1719283_304634729.0RepeatNote=LRR 9
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389798+171998_119634729.0RepeatNote=LRR 1
TgenePHF11chr13:47303119chr13:50087195ENST00000357596211108_16033293.0Zinc fingerPHD-type
TgenePHF11chr13:47303119chr13:50087195ENST0000035759621142_7833293.0Zinc fingerC2HC pre-PHD-type
TgenePHF11chr13:47303119chr13:50087195ENST00000378319110108_16072332.0Zinc fingerPHD-type
TgenePHF11chr13:47303119chr13:50087195ENST00000488958110108_16033293.0Zinc fingerPHD-type
TgenePHF11chr13:47303119chr13:50087195ENST0000048895811042_7833293.0Zinc fingerC2HC pre-PHD-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLRCH1chr13:47303119chr13:50087195ENST00000311191+1719576_692634697.0DomainCalponin-homology (CH)
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389797+1820576_692669764.0DomainCalponin-homology (CH)
HgeneLRCH1chr13:47303119chr13:50087195ENST00000389798+1719576_692634729.0DomainCalponin-homology (CH)
TgenePHF11chr13:47303119chr13:50087195ENST0000037831911042_7872332.0Zinc fingerC2HC pre-PHD-type


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Fusion Gene Sequence for LRCH1-PHF11


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>49639_49639_1_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000311191_PHF11_chr13_50087195_ENST00000357596_length(transcript)=3227nt_BP=2131nt
CCGCAGTCCTTAGCTTCCCGGGGACAGGAAACCTTCAAGACCGAGCTGCCACGGCCGCCTCCCCGCCCGCCCCCCATTCTACGCGCCTGC
CCACACCCTCCTCCCCTCCTTCCAGCGCCTTTCGGTGGAGCACTGCGGCACTCAGCCCGAGCTGCCGTTTTCCCCTCGCGGGGAACGCTG
TGACCCCCCCGCAGGAGCGGCGGGGCGGGGTGGGGGGGCCCGGGAGAAGATGGCGACGCCGGGAAGCGAACCCCAACCTTTCGTCCCGGC
CCTTTCGGTAGCTACTCTGCACCCACTTCATCATCCCCACCACCACCACCACCACCATCAGCACCACGGAGGAACCGGCGCCCCCGGCGG
GGCGGGTGGTGGCGGCGGTGGCAGCGGGGGCTTCAACCTGCCCTTGAACCGGGGTCTGGAGCGCGCGCTTGAGGAGGCGGCCAACTCCGG
GGGGCTGAACCTGAGCGCCAGGAAATTGAAGGAATTTCCCCGTACCGCAGCCCCCGGGCACGACCTCTCGGACACGGTGCAGGCAGACTT
ATCTAAAAACAGACTGGTTGAAGTTCCAATGGAATTGTGCCATTTTGTATCACTGGAAATTCTTAATCTGTATCACAACTGTATCAGAGT
CATTCCTGAGGCCATCGTTAATCTGCAGATGCTGACTTACCTGAACTTGAGTCGAAATCAGCTGTCCGCCCTGCCTGCCTGCCTGTGTGG
TCTGCCTCTCAAAGTCTTAATCGCAAGTAACAACAAACTTGGATCATTACCAGAAGAGATAGGTCAGCTCAAACAGTTAATGGAGCTGGA
TGTCAGCTGCAACGAGATCACAGCGTTGCCCCAGCAGATAGGTCAGTTGAAATCTCTACGAGAACTGAATGTCAGAAGAAATTACCTTAA
AGTTTTACCACAAGAACTAGTAGATCTTTCCTTGGTAAAGTTTGACTTTTCCTGCAACAAAGTGCTCGTGATTCCAATTTGTTTTAGAGA
GATGAAGCAGCTGCAAGTGTTACTACTTGAGAATAACCCTCTGCAGTCTCCTCCAGCACAGATTTGCACAAAGGGCAAAGTTCACATATT
TAAGTATCTGAGCATACAAGCATGCCAGATTAAGACAGCTGACTCCCTTTATCTCCACACCATGGAGAGGCCACATTTACACCAGCACGT
GGAAGATGGCAAGAAGGATTCTGATTCGGGAGTTGGAAGTGATAATGGAGATAAGCGATTATCTGCCACCGAGCCTTCTGACGAAGACAC
TGTTAGCCTCAATGTGCCAATGTCAAACATCATGGAAGAAGAACAGATCATCAAGGAGGACTCGTGCCATCGCCTTAGCCCCGTTAAAGG
GGAATTTCATCAGGAATTTCAACCGGAGCCTTCCCTTTTGGGTGACAGCACCAACTCAGGAGAAGAAAGAGACCAGTTTACTGATAGAGC
AGATGGTCTCCATTCGGAATTTATGAACTATAAGGCAAGGGCAGAAGACTGTGAAGAGCTGTTACGGATAGAAGAGGATGTGCACTGGCA
AACTGAGGGCATAATAAGTTCATCCAAAGATCAGGACATGGATATAGCAATGATCGAGCAGCTGAGAGAAGCAGTAGATTTGCTGCAAGA
TCCCAATGGATTAAGCACAGATATTACAGAGAGAAGTGTTTTAAACCTATATCCTATGGGATCAGCAGAAGCCTTAGAATTACAAGATTC
TGCACTGAATGGTCAAATACAGCTGGAGACATCTCCGGTGTGTGAGGTGCAAAGTGATCTAACATTACAGAGTAACGGGAGCCAGTATTC
TCCAAATGAGATTAGAGAGAACTCCCCTGCAGTCTCTCCTACCACAAACAGCACAGCTCCATTTGGCCTGAAGCCTCGATCAGTGTTTCT
AAGACCTCAGAGAAATTTGGAATCTATAGACCCGCAGTTTACAATCCGGAGGAAAATGGAGCAGATGAGAGAAGAGAAAGAGCTGGTGGA
ACAACTTCGTGAGAGCATTGAGATGAGATTGAAGGTCAGTCTACACGAAGACCTGGGGGCAGCCCTCATGGATGGTGTCGTCCTCTGCCA
TCTGGTCAACCACATCCGCCCACGGTCGGTTGCAAGCATCCATGTCCCATCACCAGCGGTTCTGTATTCTTCAGGACTTGTGGAATGTGA
GGATCAGGATCCACTTAATCCTGATAGAAGTTTTGATGTGGAATCAGTAAAGAAAGAAATCCAGAGAGGAAGGAAGTTGAAATGCAAATT
TTGTCATAAAAGAGGAGCCACCGTGGGATGTGATTTAAAAAACTGTAACAAGAATTACCACTTTTTCTGTGCCAAGAAGGACGACGCAGT
TCCACAGTCTGATGGAGTTCGAGGAATTTATAAACTGCTTTGCCAGCAACATGCTCAATTCCCGATCATCGCTCAAAGTGCTAAATTTTC
AGGAGTGAAAAGAAAAAGAGGAAGGAAGAAACCCCTCTCAGGCAATCATGTACAGCCACCCGAAACAATGAAATGTAATACATTCATAAG
ACAAGTGAAAGAAGAGCATGGCAGACACACAGATGCAACTGTGAAAGTTCCTTTTCTTAAGAAATGCAAGGAAGCAGGACTTCTTAATTA
CTTACTTGAAGAAATATTAGACAAAGTTCATTCAATTCCAGAAAAACTCATGGATGAGACTACTTCAGAATCAGACTATGAAGAAATCGG
GAGTGCACTTTTTGACTGTAGATTGTTCGAAGACACATTTGTAAATTTTCAAGCAGCAATAGAGAAAAAAATTCATGCATCTCAACAAAG
GTGGCAGCAGTTGAAGGAAGAGATTGAGCTACTTCAGGACTTAAAACAAACCTTGTGCTCTTTTCAAGAAAATAGAGATCTTATGTCAAG
TTCTACATCAATATCATCCCTGTCTTATTAGGGATTACCGTTTCCTAAGCCAAGAGTCATGTCAAATTGCAATCAGGCTCAAAACCAGAG
ACCAGGCTGTGAAATCCACACATCTTTAGAACTAGTCGTCTCCTCTTGGCCTCAGCAGCTCTTCCCTGTTCTTACTGGTTGACATTTTGA
TCACTCTTTGCACACTCTTGTGTTTTTTGCTCACTGTCACATTCCCAGCACCTAGTATGCTCAGTAAATGTTTGTGGAATAAGTGCATAA
AATGTTCTTAACCTTTGATTCTACTTACAGCCCATGATAGCCTCTTAGATATAATAAATTTGGATTATACTACTTTA

>49639_49639_1_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000311191_PHF11_chr13_50087195_ENST00000357596_length(amino acids)=919AA_BP=660
MPFSPRGERCDPPAGAAGRGGGAREKMATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLNRGLE
RALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ
LSALPACLCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLSLVKFDFSCNK
VLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSLYLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRL
SATEPSDEDTVSLNVPMSNIMEEEQIIKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAEDCEEL
LRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNLYPMGSAEALELQDSALNGQIQLETSPVCEVQSDL
TLQSNGSQYSPNEIRENSPAVSPTTNSTAPFGLKPRSVFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGA
ALMDGVVLCHLVNHIRPRSVASIHVPSPAVLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYH
FFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLK
KCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESDYEEIGSALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCS
FQENRDLMSSSTSISSLSY

--------------------------------------------------------------
>49639_49639_2_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000311191_PHF11_chr13_50087195_ENST00000378319_length(transcript)=3233nt_BP=2131nt
CCGCAGTCCTTAGCTTCCCGGGGACAGGAAACCTTCAAGACCGAGCTGCCACGGCCGCCTCCCCGCCCGCCCCCCATTCTACGCGCCTGC
CCACACCCTCCTCCCCTCCTTCCAGCGCCTTTCGGTGGAGCACTGCGGCACTCAGCCCGAGCTGCCGTTTTCCCCTCGCGGGGAACGCTG
TGACCCCCCCGCAGGAGCGGCGGGGCGGGGTGGGGGGGCCCGGGAGAAGATGGCGACGCCGGGAAGCGAACCCCAACCTTTCGTCCCGGC
CCTTTCGGTAGCTACTCTGCACCCACTTCATCATCCCCACCACCACCACCACCACCATCAGCACCACGGAGGAACCGGCGCCCCCGGCGG
GGCGGGTGGTGGCGGCGGTGGCAGCGGGGGCTTCAACCTGCCCTTGAACCGGGGTCTGGAGCGCGCGCTTGAGGAGGCGGCCAACTCCGG
GGGGCTGAACCTGAGCGCCAGGAAATTGAAGGAATTTCCCCGTACCGCAGCCCCCGGGCACGACCTCTCGGACACGGTGCAGGCAGACTT
ATCTAAAAACAGACTGGTTGAAGTTCCAATGGAATTGTGCCATTTTGTATCACTGGAAATTCTTAATCTGTATCACAACTGTATCAGAGT
CATTCCTGAGGCCATCGTTAATCTGCAGATGCTGACTTACCTGAACTTGAGTCGAAATCAGCTGTCCGCCCTGCCTGCCTGCCTGTGTGG
TCTGCCTCTCAAAGTCTTAATCGCAAGTAACAACAAACTTGGATCATTACCAGAAGAGATAGGTCAGCTCAAACAGTTAATGGAGCTGGA
TGTCAGCTGCAACGAGATCACAGCGTTGCCCCAGCAGATAGGTCAGTTGAAATCTCTACGAGAACTGAATGTCAGAAGAAATTACCTTAA
AGTTTTACCACAAGAACTAGTAGATCTTTCCTTGGTAAAGTTTGACTTTTCCTGCAACAAAGTGCTCGTGATTCCAATTTGTTTTAGAGA
GATGAAGCAGCTGCAAGTGTTACTACTTGAGAATAACCCTCTGCAGTCTCCTCCAGCACAGATTTGCACAAAGGGCAAAGTTCACATATT
TAAGTATCTGAGCATACAAGCATGCCAGATTAAGACAGCTGACTCCCTTTATCTCCACACCATGGAGAGGCCACATTTACACCAGCACGT
GGAAGATGGCAAGAAGGATTCTGATTCGGGAGTTGGAAGTGATAATGGAGATAAGCGATTATCTGCCACCGAGCCTTCTGACGAAGACAC
TGTTAGCCTCAATGTGCCAATGTCAAACATCATGGAAGAAGAACAGATCATCAAGGAGGACTCGTGCCATCGCCTTAGCCCCGTTAAAGG
GGAATTTCATCAGGAATTTCAACCGGAGCCTTCCCTTTTGGGTGACAGCACCAACTCAGGAGAAGAAAGAGACCAGTTTACTGATAGAGC
AGATGGTCTCCATTCGGAATTTATGAACTATAAGGCAAGGGCAGAAGACTGTGAAGAGCTGTTACGGATAGAAGAGGATGTGCACTGGCA
AACTGAGGGCATAATAAGTTCATCCAAAGATCAGGACATGGATATAGCAATGATCGAGCAGCTGAGAGAAGCAGTAGATTTGCTGCAAGA
TCCCAATGGATTAAGCACAGATATTACAGAGAGAAGTGTTTTAAACCTATATCCTATGGGATCAGCAGAAGCCTTAGAATTACAAGATTC
TGCACTGAATGGTCAAATACAGCTGGAGACATCTCCGGTGTGTGAGGTGCAAAGTGATCTAACATTACAGAGTAACGGGAGCCAGTATTC
TCCAAATGAGATTAGAGAGAACTCCCCTGCAGTCTCTCCTACCACAAACAGCACAGCTCCATTTGGCCTGAAGCCTCGATCAGTGTTTCT
AAGACCTCAGAGAAATTTGGAATCTATAGACCCGCAGTTTACAATCCGGAGGAAAATGGAGCAGATGAGAGAAGAGAAAGAGCTGGTGGA
ACAACTTCGTGAGAGCATTGAGATGAGATTGAAGGTCAGTCTACACGAAGACCTGGGGGCAGCCCTCATGGATGGTGTCGTCCTCTGCCA
TCTGGTCAACCACATCCGCCCACGGTCGGTTGCAAGCATCCATGTCCCATCACCAGCGGTTCTGTATTCTTCAGGACTTGTGGAATGTGA
GGATCAGGATCCACTTAATCCTGATAGAAGTTTTGATGTGGAATCAGTAAAGAAAGAAATCCAGAGAGGAAGGAAGTTGAAATGCAAATT
TTGTCATAAAAGAGGAGCCACCGTGGGATGTGATTTAAAAAACTGTAACAAGAATTACCACTTTTTCTGTGCCAAGAAGGACGACGCAGT
TCCACAGTCTGATGGAGTTCGAGGAATTTATAAACTGCTTTGCCAGCAACATGCTCAATTCCCGATCATCGCTCAAAGTGCTAAATTTTC
AGGAGTGAAAAGAAAAAGAGGAAGGAAGAAACCCCTCTCAGGCAATCATGTACAGCCACCCGAAACAATGAAATGTAATACATTCATAAG
ACAAGTGAAAGAAGAGCATGGCAGACACACAGATGCAACTGTGAAAGTTCCTTTTCTTAAGAAATGCAAGGAAGCAGGACTTCTTAATTA
CTTACTTGAAGAAATATTAGACAAAGTTCATTCAATTCCAGAAAAACTCATGGATGAGACTACTTCAGAATCAGACTATGAAGAAATCGG
GAGTGCACTTTTTGACTGTAGATTGTTCGAAGACACATTTGTAAATTTTCAAGCAGCAATAGAGAAAAAAATTCATGCATCTCAACAAAG
GTGGCAGCAGTTGAAGGAAGAGATTGAGCTACTTCAGGACTTAAAACAAACCTTGTGCTCTTTTCAAGAAAATAGAGATCTTATGTCAAG
TTCTACATCAATATCATCCCTGTCTTATTAGGGATTACCGTTTCCTAAGCCAAGAGTCATGTCAAATTGCAATCAGGCTCAAAACCAGAG
ACCAGGCTGTGAAATCCACACATCTTTAGAACTAGTCGTCTCCTCTTGGCCTCAGCAGCTCTTCCCTGTTCTTACTGGTTGACATTTTGA
TCACTCTTTGCACACTCTTGTGTTTTTTGCTCACTGTCACATTCCCAGCACCTAGTATGCTCAGTAAATGTTTGTGGAATAAGTGCATAA
AATGTTCTTAACCTTTGATTCTACTTACAGCCCATGATAGCCTCTTAGATATAATAAATTTGGATTATACTACTTTACTTGTA

>49639_49639_2_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000311191_PHF11_chr13_50087195_ENST00000378319_length(amino acids)=919AA_BP=660
MPFSPRGERCDPPAGAAGRGGGAREKMATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLNRGLE
RALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ
LSALPACLCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLSLVKFDFSCNK
VLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSLYLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRL
SATEPSDEDTVSLNVPMSNIMEEEQIIKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAEDCEEL
LRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNLYPMGSAEALELQDSALNGQIQLETSPVCEVQSDL
TLQSNGSQYSPNEIRENSPAVSPTTNSTAPFGLKPRSVFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGA
ALMDGVVLCHLVNHIRPRSVASIHVPSPAVLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYH
FFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLK
KCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESDYEEIGSALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCS
FQENRDLMSSSTSISSLSY

--------------------------------------------------------------
>49639_49639_3_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000311191_PHF11_chr13_50087195_ENST00000488958_length(transcript)=3222nt_BP=2131nt
CCGCAGTCCTTAGCTTCCCGGGGACAGGAAACCTTCAAGACCGAGCTGCCACGGCCGCCTCCCCGCCCGCCCCCCATTCTACGCGCCTGC
CCACACCCTCCTCCCCTCCTTCCAGCGCCTTTCGGTGGAGCACTGCGGCACTCAGCCCGAGCTGCCGTTTTCCCCTCGCGGGGAACGCTG
TGACCCCCCCGCAGGAGCGGCGGGGCGGGGTGGGGGGGCCCGGGAGAAGATGGCGACGCCGGGAAGCGAACCCCAACCTTTCGTCCCGGC
CCTTTCGGTAGCTACTCTGCACCCACTTCATCATCCCCACCACCACCACCACCACCATCAGCACCACGGAGGAACCGGCGCCCCCGGCGG
GGCGGGTGGTGGCGGCGGTGGCAGCGGGGGCTTCAACCTGCCCTTGAACCGGGGTCTGGAGCGCGCGCTTGAGGAGGCGGCCAACTCCGG
GGGGCTGAACCTGAGCGCCAGGAAATTGAAGGAATTTCCCCGTACCGCAGCCCCCGGGCACGACCTCTCGGACACGGTGCAGGCAGACTT
ATCTAAAAACAGACTGGTTGAAGTTCCAATGGAATTGTGCCATTTTGTATCACTGGAAATTCTTAATCTGTATCACAACTGTATCAGAGT
CATTCCTGAGGCCATCGTTAATCTGCAGATGCTGACTTACCTGAACTTGAGTCGAAATCAGCTGTCCGCCCTGCCTGCCTGCCTGTGTGG
TCTGCCTCTCAAAGTCTTAATCGCAAGTAACAACAAACTTGGATCATTACCAGAAGAGATAGGTCAGCTCAAACAGTTAATGGAGCTGGA
TGTCAGCTGCAACGAGATCACAGCGTTGCCCCAGCAGATAGGTCAGTTGAAATCTCTACGAGAACTGAATGTCAGAAGAAATTACCTTAA
AGTTTTACCACAAGAACTAGTAGATCTTTCCTTGGTAAAGTTTGACTTTTCCTGCAACAAAGTGCTCGTGATTCCAATTTGTTTTAGAGA
GATGAAGCAGCTGCAAGTGTTACTACTTGAGAATAACCCTCTGCAGTCTCCTCCAGCACAGATTTGCACAAAGGGCAAAGTTCACATATT
TAAGTATCTGAGCATACAAGCATGCCAGATTAAGACAGCTGACTCCCTTTATCTCCACACCATGGAGAGGCCACATTTACACCAGCACGT
GGAAGATGGCAAGAAGGATTCTGATTCGGGAGTTGGAAGTGATAATGGAGATAAGCGATTATCTGCCACCGAGCCTTCTGACGAAGACAC
TGTTAGCCTCAATGTGCCAATGTCAAACATCATGGAAGAAGAACAGATCATCAAGGAGGACTCGTGCCATCGCCTTAGCCCCGTTAAAGG
GGAATTTCATCAGGAATTTCAACCGGAGCCTTCCCTTTTGGGTGACAGCACCAACTCAGGAGAAGAAAGAGACCAGTTTACTGATAGAGC
AGATGGTCTCCATTCGGAATTTATGAACTATAAGGCAAGGGCAGAAGACTGTGAAGAGCTGTTACGGATAGAAGAGGATGTGCACTGGCA
AACTGAGGGCATAATAAGTTCATCCAAAGATCAGGACATGGATATAGCAATGATCGAGCAGCTGAGAGAAGCAGTAGATTTGCTGCAAGA
TCCCAATGGATTAAGCACAGATATTACAGAGAGAAGTGTTTTAAACCTATATCCTATGGGATCAGCAGAAGCCTTAGAATTACAAGATTC
TGCACTGAATGGTCAAATACAGCTGGAGACATCTCCGGTGTGTGAGGTGCAAAGTGATCTAACATTACAGAGTAACGGGAGCCAGTATTC
TCCAAATGAGATTAGAGAGAACTCCCCTGCAGTCTCTCCTACCACAAACAGCACAGCTCCATTTGGCCTGAAGCCTCGATCAGTGTTTCT
AAGACCTCAGAGAAATTTGGAATCTATAGACCCGCAGTTTACAATCCGGAGGAAAATGGAGCAGATGAGAGAAGAGAAAGAGCTGGTGGA
ACAACTTCGTGAGAGCATTGAGATGAGATTGAAGGTCAGTCTACACGAAGACCTGGGGGCAGCCCTCATGGATGGTGTCGTCCTCTGCCA
TCTGGTCAACCACATCCGCCCACGGTCGGTTGCAAGCATCCATGTCCCATCACCAGCGGTTCTGTATTCTTCAGGACTTGTGGAATGTGA
GGATCAGGATCCACTTAATCCTGATAGAAGTTTTGATGTGGAATCAGTAAAGAAAGAAATCCAGAGAGGAAGGAAGTTGAAATGCAAATT
TTGTCATAAAAGAGGAGCCACCGTGGGATGTGATTTAAAAAACTGTAACAAGAATTACCACTTTTTCTGTGCCAAGAAGGACGACGCAGT
TCCACAGTCTGATGGAGTTCGAGGAATTTATAAACTGCTTTGCCAGCAACATGCTCAATTCCCGATCATCGCTCAAAGTGCTAAATTTTC
AGGAGTGAAAAGAAAAAGAGGAAGGAAGAAACCCCTCTCAGGCAATCATGTACAGCCACCCGAAACAATGAAATGTAATACATTCATAAG
ACAAGTGAAAGAAGAGCATGGCAGACACACAGATGCAACTGTGAAAGTTCCTTTTCTTAAGAAATGCAAGGAAGCAGGACTTCTTAATTA
CTTACTTGAAGAAATATTAGACAAAGTTCATTCAATTCCAGAAAAACTCATGGATGAGACTACTTCAGAATCAGACTATGAAGAAATCGG
GAGTGCACTTTTTGACTGTAGATTGTTCGAAGACACATTTGTAAATTTTCAAGCAGCAATAGAGAAAAAAATTCATGCATCTCAACAAAG
GTGGCAGCAGTTGAAGGAAGAGATTGAGCTACTTCAGGACTTAAAACAAACCTTGTGCTCTTTTCAAGAAAATAGAGATCTTATGTCAAG
TTCTACATCAATATCATCCCTGTCTTATTAGGGATTACCGTTTCCTAAGCCAAGAGTCATGTCAAATTGCAATCAGGCTCAAAACCAGAG
ACCAGGCTGTGAAATCCACACATCTTTAGAACTAGTCGTCTCCTCTTGGCCTCAGCAGCTCTTCCCTGTTCTTACTGGTTGACATTTTGA
TCACTCTTTGCACACTCTTGTGTTTTTTGCTCACTGTCACATTCCCAGCACCTAGTATGCTCAGTAAATGTTTGTGGAATAAGTGCATAA
AATGTTCTTAACCTTTGATTCTACTTACAGCCCATGATAGCCTCTTAGATATAATAAATTTGGATTATACTA

>49639_49639_3_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000311191_PHF11_chr13_50087195_ENST00000488958_length(amino acids)=919AA_BP=660
MPFSPRGERCDPPAGAAGRGGGAREKMATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLNRGLE
RALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ
LSALPACLCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLSLVKFDFSCNK
VLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSLYLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRL
SATEPSDEDTVSLNVPMSNIMEEEQIIKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAEDCEEL
LRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNLYPMGSAEALELQDSALNGQIQLETSPVCEVQSDL
TLQSNGSQYSPNEIRENSPAVSPTTNSTAPFGLKPRSVFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGA
ALMDGVVLCHLVNHIRPRSVASIHVPSPAVLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYH
FFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLK
KCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESDYEEIGSALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCS
FQENRDLMSSSTSISSLSY

--------------------------------------------------------------
>49639_49639_4_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000389797_PHF11_chr13_50087195_ENST00000357596_length(transcript)=3240nt_BP=2144nt
ACACCCTCCTCCCCTCCTTCCAGCGCCTTTCGGTGGAGCACTGCGGCACTCAGCCCGAGCTGCCGTTTTCCCCTCGCGGGGAACGCTGTG
ACCCCCCCGCAGGAGCGGCGGGGCGGGGTGGGGGGGCCCGGGAGAAGATGGCGACGCCGGGAAGCGAACCCCAACCTTTCGTCCCGGCCC
TTTCGGTAGCTACTCTGCACCCACTTCATCATCCCCACCACCACCACCACCACCATCAGCACCACGGAGGAACCGGCGCCCCCGGCGGGG
CGGGTGGTGGCGGCGGTGGCAGCGGGGGCTTCAACCTGCCCTTGAACCGGGGTCTGGAGCGCGCGCTTGAGGAGGCGGCCAACTCCGGGG
GGCTGAACCTGAGCGCCAGGAAATTGAAGGAATTTCCCCGTACCGCAGCCCCCGGGCACGACCTCTCGGACACGGTGCAGGCAGACTTAT
CTAAAAACAGACTGGTTGAAGTTCCAATGGAATTGTGCCATTTTGTATCACTGGAAATTCTTAATCTGTATCACAACTGTATCAGAGTCA
TTCCTGAGGCCATCGTTAATCTGCAGATGCTGACTTACCTGAACTTGAGTCGAAATCAGCTGTCCGCCCTGCCTGCCTGCCTGTGTGGTC
TGCCTCTCAAAGTCTTAATCGCAAGTAACAACAAACTTGGATCATTACCAGAAGAGATAGGTCAGCTCAAACAGTTAATGGAGCTGGATG
TCAGCTGCAACGAGATCACAGCGTTGCCCCAGCAGATAGGTCAGTTGAAATCTCTACGAGAACTGAATGTCAGAAGAAATTACCTTAAAG
TTTTACCACAAGAACTAGTAGATCTTTCCTTGGTAAAGTTTGACTTTTCCTGCAACAAAGTGCTCGTGATTCCAATTTGTTTTAGAGAGA
TGAAGCAGCTGCAAGTGTTACTACTTGAGAATAACCCTCTGCAGTCTCCTCCAGCACAGATTTGCACAAAGGGCAAAGTTCACATATTTA
AGTATCTGAGCATACAAGCATGCCAGATTAAGACAGCTGACTCCCTTTATCTCCACACCATGGAGAGGCCACATTTACACCAGCACGTGG
AAGATGGCAAGAAGGATTCTGATTCGGGAGTTGGAAGTGATAATGGAGATAAGCGATTATCTGCCACCGAGCCTTCTGACGAAGACACTG
TTAGCCTCAATGTGCCAATGTCAAACATCATGGAAGAAGAACAGATCATCAAGGAGGACTCGTGCCATCGCCTTAGCCCCGTTAAAGGGG
AATTTCATCAGGAATTTCAACCGGAGCCTTCCCTTTTGGGTGACAGCACCAACTCAGGAGAAGAAAGAGACCAGTTTACTGATAGAGCAG
ATGGTCTCCATTCGGAATTTATGAACTATAAGGCAAGGGCAGAAGACTGTGAAGAGCTGTTACGGATAGAAGAGGATGTGCACTGGCAAA
CTGAGGGCATAATAAGTTCATCCAAAGATCAGGACATGGATATAGCAATGATCGAGCAGCTGAGAGAAGCAGTAGATTTGCTGCAAGATC
CCAATGGATTAAGCACAGATATTACAGAGAGAAGTGTTTTAAACCTATATCCTATGGGATCAGCAGAAGCCTTAGAATTACAAGATTCTG
CACTGAATGGTCAAATACAGCTGGAGACATCTCCGGTGTGTGAGGTGCAAAGTGATCTAACATTACAGAGTAACGGGAGCCAGTATTCTC
CAAATGAGATTAGAGAGAACTCCCCTGCAGTCTCTCCTACCACAAACAGCACAGCTCCATTTGGCCTGAAGCCTCGATCAGACCCAGCCC
TCATTCTTCCTCCTATCTCCTTCAACACACTTACACAGGCACAGACATGGGACAGCTCTAGCTACAGTGTTCCATCTGAAGGAGACAGTG
ACAATGTGTTTCTAAGACCTCAGAGAAATTTGGAATCTATAGACCCGCAGTTTACAATCCGGAGGAAAATGGAGCAGATGAGAGAAGAGA
AAGAGCTGGTGGAACAACTTCGTGAGAGCATTGAGATGAGATTGAAGGTCAGTCTACACGAAGACCTGGGGGCAGCCCTCATGGATGGTG
TCGTCCTCTGCCATCTGGTCAACCACATCCGCCCACGGTCGGTTGCAAGCATCCATGTCCCATCACCAGCGGTTCTGTATTCTTCAGGAC
TTGTGGAATGTGAGGATCAGGATCCACTTAATCCTGATAGAAGTTTTGATGTGGAATCAGTAAAGAAAGAAATCCAGAGAGGAAGGAAGT
TGAAATGCAAATTTTGTCATAAAAGAGGAGCCACCGTGGGATGTGATTTAAAAAACTGTAACAAGAATTACCACTTTTTCTGTGCCAAGA
AGGACGACGCAGTTCCACAGTCTGATGGAGTTCGAGGAATTTATAAACTGCTTTGCCAGCAACATGCTCAATTCCCGATCATCGCTCAAA
GTGCTAAATTTTCAGGAGTGAAAAGAAAAAGAGGAAGGAAGAAACCCCTCTCAGGCAATCATGTACAGCCACCCGAAACAATGAAATGTA
ATACATTCATAAGACAAGTGAAAGAAGAGCATGGCAGACACACAGATGCAACTGTGAAAGTTCCTTTTCTTAAGAAATGCAAGGAAGCAG
GACTTCTTAATTACTTACTTGAAGAAATATTAGACAAAGTTCATTCAATTCCAGAAAAACTCATGGATGAGACTACTTCAGAATCAGACT
ATGAAGAAATCGGGAGTGCACTTTTTGACTGTAGATTGTTCGAAGACACATTTGTAAATTTTCAAGCAGCAATAGAGAAAAAAATTCATG
CATCTCAACAAAGGTGGCAGCAGTTGAAGGAAGAGATTGAGCTACTTCAGGACTTAAAACAAACCTTGTGCTCTTTTCAAGAAAATAGAG
ATCTTATGTCAAGTTCTACATCAATATCATCCCTGTCTTATTAGGGATTACCGTTTCCTAAGCCAAGAGTCATGTCAAATTGCAATCAGG
CTCAAAACCAGAGACCAGGCTGTGAAATCCACACATCTTTAGAACTAGTCGTCTCCTCTTGGCCTCAGCAGCTCTTCCCTGTTCTTACTG
GTTGACATTTTGATCACTCTTTGCACACTCTTGTGTTTTTTGCTCACTGTCACATTCCCAGCACCTAGTATGCTCAGTAAATGTTTGTGG
AATAAGTGCATAAAATGTTCTTAACCTTTGATTCTACTTACAGCCCATGATAGCCTCTTAGATATAATAAATTTGGATTATACTACTTTA


>49639_49639_4_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000389797_PHF11_chr13_50087195_ENST00000357596_length(amino acids)=954AA_BP=695
MPFSPRGERCDPPAGAAGRGGGAREKMATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLNRGLE
RALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ
LSALPACLCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLSLVKFDFSCNK
VLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSLYLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRL
SATEPSDEDTVSLNVPMSNIMEEEQIIKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAEDCEEL
LRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNLYPMGSAEALELQDSALNGQIQLETSPVCEVQSDL
TLQSNGSQYSPNEIRENSPAVSPTTNSTAPFGLKPRSDPALILPPISFNTLTQAQTWDSSSYSVPSEGDSDNVFLRPQRNLESIDPQFTI
RRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGAALMDGVVLCHLVNHIRPRSVASIHVPSPAVLYSSGLVECEDQDPLNPDRSFDVES
VKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGN
HVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESDYEEIGSALFDCRLFEDTFVN
FQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCSFQENRDLMSSSTSISSLSY

--------------------------------------------------------------
>49639_49639_5_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000389797_PHF11_chr13_50087195_ENST00000378319_length(transcript)=3246nt_BP=2144nt
ACACCCTCCTCCCCTCCTTCCAGCGCCTTTCGGTGGAGCACTGCGGCACTCAGCCCGAGCTGCCGTTTTCCCCTCGCGGGGAACGCTGTG
ACCCCCCCGCAGGAGCGGCGGGGCGGGGTGGGGGGGCCCGGGAGAAGATGGCGACGCCGGGAAGCGAACCCCAACCTTTCGTCCCGGCCC
TTTCGGTAGCTACTCTGCACCCACTTCATCATCCCCACCACCACCACCACCACCATCAGCACCACGGAGGAACCGGCGCCCCCGGCGGGG
CGGGTGGTGGCGGCGGTGGCAGCGGGGGCTTCAACCTGCCCTTGAACCGGGGTCTGGAGCGCGCGCTTGAGGAGGCGGCCAACTCCGGGG
GGCTGAACCTGAGCGCCAGGAAATTGAAGGAATTTCCCCGTACCGCAGCCCCCGGGCACGACCTCTCGGACACGGTGCAGGCAGACTTAT
CTAAAAACAGACTGGTTGAAGTTCCAATGGAATTGTGCCATTTTGTATCACTGGAAATTCTTAATCTGTATCACAACTGTATCAGAGTCA
TTCCTGAGGCCATCGTTAATCTGCAGATGCTGACTTACCTGAACTTGAGTCGAAATCAGCTGTCCGCCCTGCCTGCCTGCCTGTGTGGTC
TGCCTCTCAAAGTCTTAATCGCAAGTAACAACAAACTTGGATCATTACCAGAAGAGATAGGTCAGCTCAAACAGTTAATGGAGCTGGATG
TCAGCTGCAACGAGATCACAGCGTTGCCCCAGCAGATAGGTCAGTTGAAATCTCTACGAGAACTGAATGTCAGAAGAAATTACCTTAAAG
TTTTACCACAAGAACTAGTAGATCTTTCCTTGGTAAAGTTTGACTTTTCCTGCAACAAAGTGCTCGTGATTCCAATTTGTTTTAGAGAGA
TGAAGCAGCTGCAAGTGTTACTACTTGAGAATAACCCTCTGCAGTCTCCTCCAGCACAGATTTGCACAAAGGGCAAAGTTCACATATTTA
AGTATCTGAGCATACAAGCATGCCAGATTAAGACAGCTGACTCCCTTTATCTCCACACCATGGAGAGGCCACATTTACACCAGCACGTGG
AAGATGGCAAGAAGGATTCTGATTCGGGAGTTGGAAGTGATAATGGAGATAAGCGATTATCTGCCACCGAGCCTTCTGACGAAGACACTG
TTAGCCTCAATGTGCCAATGTCAAACATCATGGAAGAAGAACAGATCATCAAGGAGGACTCGTGCCATCGCCTTAGCCCCGTTAAAGGGG
AATTTCATCAGGAATTTCAACCGGAGCCTTCCCTTTTGGGTGACAGCACCAACTCAGGAGAAGAAAGAGACCAGTTTACTGATAGAGCAG
ATGGTCTCCATTCGGAATTTATGAACTATAAGGCAAGGGCAGAAGACTGTGAAGAGCTGTTACGGATAGAAGAGGATGTGCACTGGCAAA
CTGAGGGCATAATAAGTTCATCCAAAGATCAGGACATGGATATAGCAATGATCGAGCAGCTGAGAGAAGCAGTAGATTTGCTGCAAGATC
CCAATGGATTAAGCACAGATATTACAGAGAGAAGTGTTTTAAACCTATATCCTATGGGATCAGCAGAAGCCTTAGAATTACAAGATTCTG
CACTGAATGGTCAAATACAGCTGGAGACATCTCCGGTGTGTGAGGTGCAAAGTGATCTAACATTACAGAGTAACGGGAGCCAGTATTCTC
CAAATGAGATTAGAGAGAACTCCCCTGCAGTCTCTCCTACCACAAACAGCACAGCTCCATTTGGCCTGAAGCCTCGATCAGACCCAGCCC
TCATTCTTCCTCCTATCTCCTTCAACACACTTACACAGGCACAGACATGGGACAGCTCTAGCTACAGTGTTCCATCTGAAGGAGACAGTG
ACAATGTGTTTCTAAGACCTCAGAGAAATTTGGAATCTATAGACCCGCAGTTTACAATCCGGAGGAAAATGGAGCAGATGAGAGAAGAGA
AAGAGCTGGTGGAACAACTTCGTGAGAGCATTGAGATGAGATTGAAGGTCAGTCTACACGAAGACCTGGGGGCAGCCCTCATGGATGGTG
TCGTCCTCTGCCATCTGGTCAACCACATCCGCCCACGGTCGGTTGCAAGCATCCATGTCCCATCACCAGCGGTTCTGTATTCTTCAGGAC
TTGTGGAATGTGAGGATCAGGATCCACTTAATCCTGATAGAAGTTTTGATGTGGAATCAGTAAAGAAAGAAATCCAGAGAGGAAGGAAGT
TGAAATGCAAATTTTGTCATAAAAGAGGAGCCACCGTGGGATGTGATTTAAAAAACTGTAACAAGAATTACCACTTTTTCTGTGCCAAGA
AGGACGACGCAGTTCCACAGTCTGATGGAGTTCGAGGAATTTATAAACTGCTTTGCCAGCAACATGCTCAATTCCCGATCATCGCTCAAA
GTGCTAAATTTTCAGGAGTGAAAAGAAAAAGAGGAAGGAAGAAACCCCTCTCAGGCAATCATGTACAGCCACCCGAAACAATGAAATGTA
ATACATTCATAAGACAAGTGAAAGAAGAGCATGGCAGACACACAGATGCAACTGTGAAAGTTCCTTTTCTTAAGAAATGCAAGGAAGCAG
GACTTCTTAATTACTTACTTGAAGAAATATTAGACAAAGTTCATTCAATTCCAGAAAAACTCATGGATGAGACTACTTCAGAATCAGACT
ATGAAGAAATCGGGAGTGCACTTTTTGACTGTAGATTGTTCGAAGACACATTTGTAAATTTTCAAGCAGCAATAGAGAAAAAAATTCATG
CATCTCAACAAAGGTGGCAGCAGTTGAAGGAAGAGATTGAGCTACTTCAGGACTTAAAACAAACCTTGTGCTCTTTTCAAGAAAATAGAG
ATCTTATGTCAAGTTCTACATCAATATCATCCCTGTCTTATTAGGGATTACCGTTTCCTAAGCCAAGAGTCATGTCAAATTGCAATCAGG
CTCAAAACCAGAGACCAGGCTGTGAAATCCACACATCTTTAGAACTAGTCGTCTCCTCTTGGCCTCAGCAGCTCTTCCCTGTTCTTACTG
GTTGACATTTTGATCACTCTTTGCACACTCTTGTGTTTTTTGCTCACTGTCACATTCCCAGCACCTAGTATGCTCAGTAAATGTTTGTGG
AATAAGTGCATAAAATGTTCTTAACCTTTGATTCTACTTACAGCCCATGATAGCCTCTTAGATATAATAAATTTGGATTATACTACTTTA
CTTGTA

>49639_49639_5_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000389797_PHF11_chr13_50087195_ENST00000378319_length(amino acids)=954AA_BP=695
MPFSPRGERCDPPAGAAGRGGGAREKMATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLNRGLE
RALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ
LSALPACLCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLSLVKFDFSCNK
VLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSLYLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRL
SATEPSDEDTVSLNVPMSNIMEEEQIIKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAEDCEEL
LRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNLYPMGSAEALELQDSALNGQIQLETSPVCEVQSDL
TLQSNGSQYSPNEIRENSPAVSPTTNSTAPFGLKPRSDPALILPPISFNTLTQAQTWDSSSYSVPSEGDSDNVFLRPQRNLESIDPQFTI
RRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGAALMDGVVLCHLVNHIRPRSVASIHVPSPAVLYSSGLVECEDQDPLNPDRSFDVES
VKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGN
HVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESDYEEIGSALFDCRLFEDTFVN
FQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCSFQENRDLMSSSTSISSLSY

--------------------------------------------------------------
>49639_49639_6_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000389797_PHF11_chr13_50087195_ENST00000488958_length(transcript)=3235nt_BP=2144nt
ACACCCTCCTCCCCTCCTTCCAGCGCCTTTCGGTGGAGCACTGCGGCACTCAGCCCGAGCTGCCGTTTTCCCCTCGCGGGGAACGCTGTG
ACCCCCCCGCAGGAGCGGCGGGGCGGGGTGGGGGGGCCCGGGAGAAGATGGCGACGCCGGGAAGCGAACCCCAACCTTTCGTCCCGGCCC
TTTCGGTAGCTACTCTGCACCCACTTCATCATCCCCACCACCACCACCACCACCATCAGCACCACGGAGGAACCGGCGCCCCCGGCGGGG
CGGGTGGTGGCGGCGGTGGCAGCGGGGGCTTCAACCTGCCCTTGAACCGGGGTCTGGAGCGCGCGCTTGAGGAGGCGGCCAACTCCGGGG
GGCTGAACCTGAGCGCCAGGAAATTGAAGGAATTTCCCCGTACCGCAGCCCCCGGGCACGACCTCTCGGACACGGTGCAGGCAGACTTAT
CTAAAAACAGACTGGTTGAAGTTCCAATGGAATTGTGCCATTTTGTATCACTGGAAATTCTTAATCTGTATCACAACTGTATCAGAGTCA
TTCCTGAGGCCATCGTTAATCTGCAGATGCTGACTTACCTGAACTTGAGTCGAAATCAGCTGTCCGCCCTGCCTGCCTGCCTGTGTGGTC
TGCCTCTCAAAGTCTTAATCGCAAGTAACAACAAACTTGGATCATTACCAGAAGAGATAGGTCAGCTCAAACAGTTAATGGAGCTGGATG
TCAGCTGCAACGAGATCACAGCGTTGCCCCAGCAGATAGGTCAGTTGAAATCTCTACGAGAACTGAATGTCAGAAGAAATTACCTTAAAG
TTTTACCACAAGAACTAGTAGATCTTTCCTTGGTAAAGTTTGACTTTTCCTGCAACAAAGTGCTCGTGATTCCAATTTGTTTTAGAGAGA
TGAAGCAGCTGCAAGTGTTACTACTTGAGAATAACCCTCTGCAGTCTCCTCCAGCACAGATTTGCACAAAGGGCAAAGTTCACATATTTA
AGTATCTGAGCATACAAGCATGCCAGATTAAGACAGCTGACTCCCTTTATCTCCACACCATGGAGAGGCCACATTTACACCAGCACGTGG
AAGATGGCAAGAAGGATTCTGATTCGGGAGTTGGAAGTGATAATGGAGATAAGCGATTATCTGCCACCGAGCCTTCTGACGAAGACACTG
TTAGCCTCAATGTGCCAATGTCAAACATCATGGAAGAAGAACAGATCATCAAGGAGGACTCGTGCCATCGCCTTAGCCCCGTTAAAGGGG
AATTTCATCAGGAATTTCAACCGGAGCCTTCCCTTTTGGGTGACAGCACCAACTCAGGAGAAGAAAGAGACCAGTTTACTGATAGAGCAG
ATGGTCTCCATTCGGAATTTATGAACTATAAGGCAAGGGCAGAAGACTGTGAAGAGCTGTTACGGATAGAAGAGGATGTGCACTGGCAAA
CTGAGGGCATAATAAGTTCATCCAAAGATCAGGACATGGATATAGCAATGATCGAGCAGCTGAGAGAAGCAGTAGATTTGCTGCAAGATC
CCAATGGATTAAGCACAGATATTACAGAGAGAAGTGTTTTAAACCTATATCCTATGGGATCAGCAGAAGCCTTAGAATTACAAGATTCTG
CACTGAATGGTCAAATACAGCTGGAGACATCTCCGGTGTGTGAGGTGCAAAGTGATCTAACATTACAGAGTAACGGGAGCCAGTATTCTC
CAAATGAGATTAGAGAGAACTCCCCTGCAGTCTCTCCTACCACAAACAGCACAGCTCCATTTGGCCTGAAGCCTCGATCAGACCCAGCCC
TCATTCTTCCTCCTATCTCCTTCAACACACTTACACAGGCACAGACATGGGACAGCTCTAGCTACAGTGTTCCATCTGAAGGAGACAGTG
ACAATGTGTTTCTAAGACCTCAGAGAAATTTGGAATCTATAGACCCGCAGTTTACAATCCGGAGGAAAATGGAGCAGATGAGAGAAGAGA
AAGAGCTGGTGGAACAACTTCGTGAGAGCATTGAGATGAGATTGAAGGTCAGTCTACACGAAGACCTGGGGGCAGCCCTCATGGATGGTG
TCGTCCTCTGCCATCTGGTCAACCACATCCGCCCACGGTCGGTTGCAAGCATCCATGTCCCATCACCAGCGGTTCTGTATTCTTCAGGAC
TTGTGGAATGTGAGGATCAGGATCCACTTAATCCTGATAGAAGTTTTGATGTGGAATCAGTAAAGAAAGAAATCCAGAGAGGAAGGAAGT
TGAAATGCAAATTTTGTCATAAAAGAGGAGCCACCGTGGGATGTGATTTAAAAAACTGTAACAAGAATTACCACTTTTTCTGTGCCAAGA
AGGACGACGCAGTTCCACAGTCTGATGGAGTTCGAGGAATTTATAAACTGCTTTGCCAGCAACATGCTCAATTCCCGATCATCGCTCAAA
GTGCTAAATTTTCAGGAGTGAAAAGAAAAAGAGGAAGGAAGAAACCCCTCTCAGGCAATCATGTACAGCCACCCGAAACAATGAAATGTA
ATACATTCATAAGACAAGTGAAAGAAGAGCATGGCAGACACACAGATGCAACTGTGAAAGTTCCTTTTCTTAAGAAATGCAAGGAAGCAG
GACTTCTTAATTACTTACTTGAAGAAATATTAGACAAAGTTCATTCAATTCCAGAAAAACTCATGGATGAGACTACTTCAGAATCAGACT
ATGAAGAAATCGGGAGTGCACTTTTTGACTGTAGATTGTTCGAAGACACATTTGTAAATTTTCAAGCAGCAATAGAGAAAAAAATTCATG
CATCTCAACAAAGGTGGCAGCAGTTGAAGGAAGAGATTGAGCTACTTCAGGACTTAAAACAAACCTTGTGCTCTTTTCAAGAAAATAGAG
ATCTTATGTCAAGTTCTACATCAATATCATCCCTGTCTTATTAGGGATTACCGTTTCCTAAGCCAAGAGTCATGTCAAATTGCAATCAGG
CTCAAAACCAGAGACCAGGCTGTGAAATCCACACATCTTTAGAACTAGTCGTCTCCTCTTGGCCTCAGCAGCTCTTCCCTGTTCTTACTG
GTTGACATTTTGATCACTCTTTGCACACTCTTGTGTTTTTTGCTCACTGTCACATTCCCAGCACCTAGTATGCTCAGTAAATGTTTGTGG
AATAAGTGCATAAAATGTTCTTAACCTTTGATTCTACTTACAGCCCATGATAGCCTCTTAGATATAATAAATTTGGATTATACTA

>49639_49639_6_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000389797_PHF11_chr13_50087195_ENST00000488958_length(amino acids)=954AA_BP=695
MPFSPRGERCDPPAGAAGRGGGAREKMATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLNRGLE
RALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ
LSALPACLCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLSLVKFDFSCNK
VLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSLYLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRL
SATEPSDEDTVSLNVPMSNIMEEEQIIKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAEDCEEL
LRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNLYPMGSAEALELQDSALNGQIQLETSPVCEVQSDL
TLQSNGSQYSPNEIRENSPAVSPTTNSTAPFGLKPRSDPALILPPISFNTLTQAQTWDSSSYSVPSEGDSDNVFLRPQRNLESIDPQFTI
RRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGAALMDGVVLCHLVNHIRPRSVASIHVPSPAVLYSSGLVECEDQDPLNPDRSFDVES
VKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGN
HVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESDYEEIGSALFDCRLFEDTFVN
FQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCSFQENRDLMSSSTSISSLSY

--------------------------------------------------------------
>49639_49639_7_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000389798_PHF11_chr13_50087195_ENST00000357596_length(transcript)=3195nt_BP=2099nt
CTTCAAGACCGAGCTGCCACGGCCGCCTCCCCGCCCGCCCCCCATTCTACGCGCCTGCCCACACCCTCCTCCCCTCCTTCCAGCGCCTTT
CGGTGGAGCACTGCGGCACTCAGCCCGAGCTGCCGTTTTCCCCTCGCGGGGAACGCTGTGACCCCCCCGCAGGAGCGGCGGGGCGGGGTG
GGGGGGCCCGGGAGAAGATGGCGACGCCGGGAAGCGAACCCCAACCTTTCGTCCCGGCCCTTTCGGTAGCTACTCTGCACCCACTTCATC
ATCCCCACCACCACCACCACCACCATCAGCACCACGGAGGAACCGGCGCCCCCGGCGGGGCGGGTGGTGGCGGCGGTGGCAGCGGGGGCT
TCAACCTGCCCTTGAACCGGGGTCTGGAGCGCGCGCTTGAGGAGGCGGCCAACTCCGGGGGGCTGAACCTGAGCGCCAGGAAATTGAAGG
AATTTCCCCGTACCGCAGCCCCCGGGCACGACCTCTCGGACACGGTGCAGGCAGACTTATCTAAAAACAGACTGGTTGAAGTTCCAATGG
AATTGTGCCATTTTGTATCACTGGAAATTCTTAATCTGTATCACAACTGTATCAGAGTCATTCCTGAGGCCATCGTTAATCTGCAGATGC
TGACTTACCTGAACTTGAGTCGAAATCAGCTGTCCGCCCTGCCTGCCTGCCTGTGTGGTCTGCCTCTCAAAGTCTTAATCGCAAGTAACA
ACAAACTTGGATCATTACCAGAAGAGATAGGTCAGCTCAAACAGTTAATGGAGCTGGATGTCAGCTGCAACGAGATCACAGCGTTGCCCC
AGCAGATAGGTCAGTTGAAATCTCTACGAGAACTGAATGTCAGAAGAAATTACCTTAAAGTTTTACCACAAGAACTAGTAGATCTTTCCT
TGGTAAAGTTTGACTTTTCCTGCAACAAAGTGCTCGTGATTCCAATTTGTTTTAGAGAGATGAAGCAGCTGCAAGTGTTACTACTTGAGA
ATAACCCTCTGCAGTCTCCTCCAGCACAGATTTGCACAAAGGGCAAAGTTCACATATTTAAGTATCTGAGCATACAAGCATGCCAGATTA
AGACAGCTGACTCCCTTTATCTCCACACCATGGAGAGGCCACATTTACACCAGCACGTGGAAGATGGCAAGAAGGATTCTGATTCGGGAG
TTGGAAGTGATAATGGAGATAAGCGATTATCTGCCACCGAGCCTTCTGACGAAGACACTGTTAGCCTCAATGTGCCAATGTCAAACATCA
TGGAAGAAGAACAGATCATCAAGGAGGACTCGTGCCATCGCCTTAGCCCCGTTAAAGGGGAATTTCATCAGGAATTTCAACCGGAGCCTT
CCCTTTTGGGTGACAGCACCAACTCAGGAGAAGAAAGAGACCAGTTTACTGATAGAGCAGATGGTCTCCATTCGGAATTTATGAACTATA
AGGCAAGGGCAGAAGACTGTGAAGAGCTGTTACGGATAGAAGAGGATGTGCACTGGCAAACTGAGGGCATAATAAGTTCATCCAAAGATC
AGGACATGGATATAGCAATGATCGAGCAGCTGAGAGAAGCAGTAGATTTGCTGCAAGATCCCAATGGATTAAGCACAGATATTACAGAGA
GAAGTGTTTTAAACCTATATCCTATGGGATCAGCAGAAGCCTTAGAATTACAAGATTCTGCACTGAATGGTCAAATACAGCTGGAGACAT
CTCCGGTGTGTGAGGTGCAAAGTGATCTAACATTACAGAGTAACGGGAGCCAGTATTCTCCAAATGAGATTAGAGAGAACTCCCCTGCAG
TCTCTCCTACCACAAACAGCACAGCTCCATTTGGCCTGAAGCCTCGATCAGTGTTTCTAAGACCTCAGAGAAATTTGGAATCTATAGACC
CGCAGTTTACAATCCGGAGGAAAATGGAGCAGATGAGAGAAGAGAAAGAGCTGGTGGAACAACTTCGTGAGAGCATTGAGATGAGATTGA
AGGTCAGTCTACACGAAGACCTGGGGGCAGCCCTCATGGATGGTGTCGTCCTCTGCCATCTGGTCAACCACATCCGCCCACGGTCGGTTG
CAAGCATCCATGTCCCATCACCAGCGGTTCTGTATTCTTCAGGACTTGTGGAATGTGAGGATCAGGATCCACTTAATCCTGATAGAAGTT
TTGATGTGGAATCAGTAAAGAAAGAAATCCAGAGAGGAAGGAAGTTGAAATGCAAATTTTGTCATAAAAGAGGAGCCACCGTGGGATGTG
ATTTAAAAAACTGTAACAAGAATTACCACTTTTTCTGTGCCAAGAAGGACGACGCAGTTCCACAGTCTGATGGAGTTCGAGGAATTTATA
AACTGCTTTGCCAGCAACATGCTCAATTCCCGATCATCGCTCAAAGTGCTAAATTTTCAGGAGTGAAAAGAAAAAGAGGAAGGAAGAAAC
CCCTCTCAGGCAATCATGTACAGCCACCCGAAACAATGAAATGTAATACATTCATAAGACAAGTGAAAGAAGAGCATGGCAGACACACAG
ATGCAACTGTGAAAGTTCCTTTTCTTAAGAAATGCAAGGAAGCAGGACTTCTTAATTACTTACTTGAAGAAATATTAGACAAAGTTCATT
CAATTCCAGAAAAACTCATGGATGAGACTACTTCAGAATCAGACTATGAAGAAATCGGGAGTGCACTTTTTGACTGTAGATTGTTCGAAG
ACACATTTGTAAATTTTCAAGCAGCAATAGAGAAAAAAATTCATGCATCTCAACAAAGGTGGCAGCAGTTGAAGGAAGAGATTGAGCTAC
TTCAGGACTTAAAACAAACCTTGTGCTCTTTTCAAGAAAATAGAGATCTTATGTCAAGTTCTACATCAATATCATCCCTGTCTTATTAGG
GATTACCGTTTCCTAAGCCAAGAGTCATGTCAAATTGCAATCAGGCTCAAAACCAGAGACCAGGCTGTGAAATCCACACATCTTTAGAAC
TAGTCGTCTCCTCTTGGCCTCAGCAGCTCTTCCCTGTTCTTACTGGTTGACATTTTGATCACTCTTTGCACACTCTTGTGTTTTTTGCTC
ACTGTCACATTCCCAGCACCTAGTATGCTCAGTAAATGTTTGTGGAATAAGTGCATAAAATGTTCTTAACCTTTGATTCTACTTACAGCC
CATGATAGCCTCTTAGATATAATAAATTTGGATTATACTACTTTA

>49639_49639_7_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000389798_PHF11_chr13_50087195_ENST00000357596_length(amino acids)=919AA_BP=660
MPFSPRGERCDPPAGAAGRGGGAREKMATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLNRGLE
RALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ
LSALPACLCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLSLVKFDFSCNK
VLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSLYLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRL
SATEPSDEDTVSLNVPMSNIMEEEQIIKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAEDCEEL
LRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNLYPMGSAEALELQDSALNGQIQLETSPVCEVQSDL
TLQSNGSQYSPNEIRENSPAVSPTTNSTAPFGLKPRSVFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGA
ALMDGVVLCHLVNHIRPRSVASIHVPSPAVLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYH
FFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLK
KCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESDYEEIGSALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCS
FQENRDLMSSSTSISSLSY

--------------------------------------------------------------
>49639_49639_8_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000389798_PHF11_chr13_50087195_ENST00000378319_length(transcript)=3201nt_BP=2099nt
CTTCAAGACCGAGCTGCCACGGCCGCCTCCCCGCCCGCCCCCCATTCTACGCGCCTGCCCACACCCTCCTCCCCTCCTTCCAGCGCCTTT
CGGTGGAGCACTGCGGCACTCAGCCCGAGCTGCCGTTTTCCCCTCGCGGGGAACGCTGTGACCCCCCCGCAGGAGCGGCGGGGCGGGGTG
GGGGGGCCCGGGAGAAGATGGCGACGCCGGGAAGCGAACCCCAACCTTTCGTCCCGGCCCTTTCGGTAGCTACTCTGCACCCACTTCATC
ATCCCCACCACCACCACCACCACCATCAGCACCACGGAGGAACCGGCGCCCCCGGCGGGGCGGGTGGTGGCGGCGGTGGCAGCGGGGGCT
TCAACCTGCCCTTGAACCGGGGTCTGGAGCGCGCGCTTGAGGAGGCGGCCAACTCCGGGGGGCTGAACCTGAGCGCCAGGAAATTGAAGG
AATTTCCCCGTACCGCAGCCCCCGGGCACGACCTCTCGGACACGGTGCAGGCAGACTTATCTAAAAACAGACTGGTTGAAGTTCCAATGG
AATTGTGCCATTTTGTATCACTGGAAATTCTTAATCTGTATCACAACTGTATCAGAGTCATTCCTGAGGCCATCGTTAATCTGCAGATGC
TGACTTACCTGAACTTGAGTCGAAATCAGCTGTCCGCCCTGCCTGCCTGCCTGTGTGGTCTGCCTCTCAAAGTCTTAATCGCAAGTAACA
ACAAACTTGGATCATTACCAGAAGAGATAGGTCAGCTCAAACAGTTAATGGAGCTGGATGTCAGCTGCAACGAGATCACAGCGTTGCCCC
AGCAGATAGGTCAGTTGAAATCTCTACGAGAACTGAATGTCAGAAGAAATTACCTTAAAGTTTTACCACAAGAACTAGTAGATCTTTCCT
TGGTAAAGTTTGACTTTTCCTGCAACAAAGTGCTCGTGATTCCAATTTGTTTTAGAGAGATGAAGCAGCTGCAAGTGTTACTACTTGAGA
ATAACCCTCTGCAGTCTCCTCCAGCACAGATTTGCACAAAGGGCAAAGTTCACATATTTAAGTATCTGAGCATACAAGCATGCCAGATTA
AGACAGCTGACTCCCTTTATCTCCACACCATGGAGAGGCCACATTTACACCAGCACGTGGAAGATGGCAAGAAGGATTCTGATTCGGGAG
TTGGAAGTGATAATGGAGATAAGCGATTATCTGCCACCGAGCCTTCTGACGAAGACACTGTTAGCCTCAATGTGCCAATGTCAAACATCA
TGGAAGAAGAACAGATCATCAAGGAGGACTCGTGCCATCGCCTTAGCCCCGTTAAAGGGGAATTTCATCAGGAATTTCAACCGGAGCCTT
CCCTTTTGGGTGACAGCACCAACTCAGGAGAAGAAAGAGACCAGTTTACTGATAGAGCAGATGGTCTCCATTCGGAATTTATGAACTATA
AGGCAAGGGCAGAAGACTGTGAAGAGCTGTTACGGATAGAAGAGGATGTGCACTGGCAAACTGAGGGCATAATAAGTTCATCCAAAGATC
AGGACATGGATATAGCAATGATCGAGCAGCTGAGAGAAGCAGTAGATTTGCTGCAAGATCCCAATGGATTAAGCACAGATATTACAGAGA
GAAGTGTTTTAAACCTATATCCTATGGGATCAGCAGAAGCCTTAGAATTACAAGATTCTGCACTGAATGGTCAAATACAGCTGGAGACAT
CTCCGGTGTGTGAGGTGCAAAGTGATCTAACATTACAGAGTAACGGGAGCCAGTATTCTCCAAATGAGATTAGAGAGAACTCCCCTGCAG
TCTCTCCTACCACAAACAGCACAGCTCCATTTGGCCTGAAGCCTCGATCAGTGTTTCTAAGACCTCAGAGAAATTTGGAATCTATAGACC
CGCAGTTTACAATCCGGAGGAAAATGGAGCAGATGAGAGAAGAGAAAGAGCTGGTGGAACAACTTCGTGAGAGCATTGAGATGAGATTGA
AGGTCAGTCTACACGAAGACCTGGGGGCAGCCCTCATGGATGGTGTCGTCCTCTGCCATCTGGTCAACCACATCCGCCCACGGTCGGTTG
CAAGCATCCATGTCCCATCACCAGCGGTTCTGTATTCTTCAGGACTTGTGGAATGTGAGGATCAGGATCCACTTAATCCTGATAGAAGTT
TTGATGTGGAATCAGTAAAGAAAGAAATCCAGAGAGGAAGGAAGTTGAAATGCAAATTTTGTCATAAAAGAGGAGCCACCGTGGGATGTG
ATTTAAAAAACTGTAACAAGAATTACCACTTTTTCTGTGCCAAGAAGGACGACGCAGTTCCACAGTCTGATGGAGTTCGAGGAATTTATA
AACTGCTTTGCCAGCAACATGCTCAATTCCCGATCATCGCTCAAAGTGCTAAATTTTCAGGAGTGAAAAGAAAAAGAGGAAGGAAGAAAC
CCCTCTCAGGCAATCATGTACAGCCACCCGAAACAATGAAATGTAATACATTCATAAGACAAGTGAAAGAAGAGCATGGCAGACACACAG
ATGCAACTGTGAAAGTTCCTTTTCTTAAGAAATGCAAGGAAGCAGGACTTCTTAATTACTTACTTGAAGAAATATTAGACAAAGTTCATT
CAATTCCAGAAAAACTCATGGATGAGACTACTTCAGAATCAGACTATGAAGAAATCGGGAGTGCACTTTTTGACTGTAGATTGTTCGAAG
ACACATTTGTAAATTTTCAAGCAGCAATAGAGAAAAAAATTCATGCATCTCAACAAAGGTGGCAGCAGTTGAAGGAAGAGATTGAGCTAC
TTCAGGACTTAAAACAAACCTTGTGCTCTTTTCAAGAAAATAGAGATCTTATGTCAAGTTCTACATCAATATCATCCCTGTCTTATTAGG
GATTACCGTTTCCTAAGCCAAGAGTCATGTCAAATTGCAATCAGGCTCAAAACCAGAGACCAGGCTGTGAAATCCACACATCTTTAGAAC
TAGTCGTCTCCTCTTGGCCTCAGCAGCTCTTCCCTGTTCTTACTGGTTGACATTTTGATCACTCTTTGCACACTCTTGTGTTTTTTGCTC
ACTGTCACATTCCCAGCACCTAGTATGCTCAGTAAATGTTTGTGGAATAAGTGCATAAAATGTTCTTAACCTTTGATTCTACTTACAGCC
CATGATAGCCTCTTAGATATAATAAATTTGGATTATACTACTTTACTTGTA

>49639_49639_8_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000389798_PHF11_chr13_50087195_ENST00000378319_length(amino acids)=919AA_BP=660
MPFSPRGERCDPPAGAAGRGGGAREKMATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLNRGLE
RALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ
LSALPACLCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLSLVKFDFSCNK
VLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSLYLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRL
SATEPSDEDTVSLNVPMSNIMEEEQIIKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAEDCEEL
LRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNLYPMGSAEALELQDSALNGQIQLETSPVCEVQSDL
TLQSNGSQYSPNEIRENSPAVSPTTNSTAPFGLKPRSVFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGA
ALMDGVVLCHLVNHIRPRSVASIHVPSPAVLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYH
FFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLK
KCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESDYEEIGSALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCS
FQENRDLMSSSTSISSLSY

--------------------------------------------------------------
>49639_49639_9_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000389798_PHF11_chr13_50087195_ENST00000488958_length(transcript)=3190nt_BP=2099nt
CTTCAAGACCGAGCTGCCACGGCCGCCTCCCCGCCCGCCCCCCATTCTACGCGCCTGCCCACACCCTCCTCCCCTCCTTCCAGCGCCTTT
CGGTGGAGCACTGCGGCACTCAGCCCGAGCTGCCGTTTTCCCCTCGCGGGGAACGCTGTGACCCCCCCGCAGGAGCGGCGGGGCGGGGTG
GGGGGGCCCGGGAGAAGATGGCGACGCCGGGAAGCGAACCCCAACCTTTCGTCCCGGCCCTTTCGGTAGCTACTCTGCACCCACTTCATC
ATCCCCACCACCACCACCACCACCATCAGCACCACGGAGGAACCGGCGCCCCCGGCGGGGCGGGTGGTGGCGGCGGTGGCAGCGGGGGCT
TCAACCTGCCCTTGAACCGGGGTCTGGAGCGCGCGCTTGAGGAGGCGGCCAACTCCGGGGGGCTGAACCTGAGCGCCAGGAAATTGAAGG
AATTTCCCCGTACCGCAGCCCCCGGGCACGACCTCTCGGACACGGTGCAGGCAGACTTATCTAAAAACAGACTGGTTGAAGTTCCAATGG
AATTGTGCCATTTTGTATCACTGGAAATTCTTAATCTGTATCACAACTGTATCAGAGTCATTCCTGAGGCCATCGTTAATCTGCAGATGC
TGACTTACCTGAACTTGAGTCGAAATCAGCTGTCCGCCCTGCCTGCCTGCCTGTGTGGTCTGCCTCTCAAAGTCTTAATCGCAAGTAACA
ACAAACTTGGATCATTACCAGAAGAGATAGGTCAGCTCAAACAGTTAATGGAGCTGGATGTCAGCTGCAACGAGATCACAGCGTTGCCCC
AGCAGATAGGTCAGTTGAAATCTCTACGAGAACTGAATGTCAGAAGAAATTACCTTAAAGTTTTACCACAAGAACTAGTAGATCTTTCCT
TGGTAAAGTTTGACTTTTCCTGCAACAAAGTGCTCGTGATTCCAATTTGTTTTAGAGAGATGAAGCAGCTGCAAGTGTTACTACTTGAGA
ATAACCCTCTGCAGTCTCCTCCAGCACAGATTTGCACAAAGGGCAAAGTTCACATATTTAAGTATCTGAGCATACAAGCATGCCAGATTA
AGACAGCTGACTCCCTTTATCTCCACACCATGGAGAGGCCACATTTACACCAGCACGTGGAAGATGGCAAGAAGGATTCTGATTCGGGAG
TTGGAAGTGATAATGGAGATAAGCGATTATCTGCCACCGAGCCTTCTGACGAAGACACTGTTAGCCTCAATGTGCCAATGTCAAACATCA
TGGAAGAAGAACAGATCATCAAGGAGGACTCGTGCCATCGCCTTAGCCCCGTTAAAGGGGAATTTCATCAGGAATTTCAACCGGAGCCTT
CCCTTTTGGGTGACAGCACCAACTCAGGAGAAGAAAGAGACCAGTTTACTGATAGAGCAGATGGTCTCCATTCGGAATTTATGAACTATA
AGGCAAGGGCAGAAGACTGTGAAGAGCTGTTACGGATAGAAGAGGATGTGCACTGGCAAACTGAGGGCATAATAAGTTCATCCAAAGATC
AGGACATGGATATAGCAATGATCGAGCAGCTGAGAGAAGCAGTAGATTTGCTGCAAGATCCCAATGGATTAAGCACAGATATTACAGAGA
GAAGTGTTTTAAACCTATATCCTATGGGATCAGCAGAAGCCTTAGAATTACAAGATTCTGCACTGAATGGTCAAATACAGCTGGAGACAT
CTCCGGTGTGTGAGGTGCAAAGTGATCTAACATTACAGAGTAACGGGAGCCAGTATTCTCCAAATGAGATTAGAGAGAACTCCCCTGCAG
TCTCTCCTACCACAAACAGCACAGCTCCATTTGGCCTGAAGCCTCGATCAGTGTTTCTAAGACCTCAGAGAAATTTGGAATCTATAGACC
CGCAGTTTACAATCCGGAGGAAAATGGAGCAGATGAGAGAAGAGAAAGAGCTGGTGGAACAACTTCGTGAGAGCATTGAGATGAGATTGA
AGGTCAGTCTACACGAAGACCTGGGGGCAGCCCTCATGGATGGTGTCGTCCTCTGCCATCTGGTCAACCACATCCGCCCACGGTCGGTTG
CAAGCATCCATGTCCCATCACCAGCGGTTCTGTATTCTTCAGGACTTGTGGAATGTGAGGATCAGGATCCACTTAATCCTGATAGAAGTT
TTGATGTGGAATCAGTAAAGAAAGAAATCCAGAGAGGAAGGAAGTTGAAATGCAAATTTTGTCATAAAAGAGGAGCCACCGTGGGATGTG
ATTTAAAAAACTGTAACAAGAATTACCACTTTTTCTGTGCCAAGAAGGACGACGCAGTTCCACAGTCTGATGGAGTTCGAGGAATTTATA
AACTGCTTTGCCAGCAACATGCTCAATTCCCGATCATCGCTCAAAGTGCTAAATTTTCAGGAGTGAAAAGAAAAAGAGGAAGGAAGAAAC
CCCTCTCAGGCAATCATGTACAGCCACCCGAAACAATGAAATGTAATACATTCATAAGACAAGTGAAAGAAGAGCATGGCAGACACACAG
ATGCAACTGTGAAAGTTCCTTTTCTTAAGAAATGCAAGGAAGCAGGACTTCTTAATTACTTACTTGAAGAAATATTAGACAAAGTTCATT
CAATTCCAGAAAAACTCATGGATGAGACTACTTCAGAATCAGACTATGAAGAAATCGGGAGTGCACTTTTTGACTGTAGATTGTTCGAAG
ACACATTTGTAAATTTTCAAGCAGCAATAGAGAAAAAAATTCATGCATCTCAACAAAGGTGGCAGCAGTTGAAGGAAGAGATTGAGCTAC
TTCAGGACTTAAAACAAACCTTGTGCTCTTTTCAAGAAAATAGAGATCTTATGTCAAGTTCTACATCAATATCATCCCTGTCTTATTAGG
GATTACCGTTTCCTAAGCCAAGAGTCATGTCAAATTGCAATCAGGCTCAAAACCAGAGACCAGGCTGTGAAATCCACACATCTTTAGAAC
TAGTCGTCTCCTCTTGGCCTCAGCAGCTCTTCCCTGTTCTTACTGGTTGACATTTTGATCACTCTTTGCACACTCTTGTGTTTTTTGCTC
ACTGTCACATTCCCAGCACCTAGTATGCTCAGTAAATGTTTGTGGAATAAGTGCATAAAATGTTCTTAACCTTTGATTCTACTTACAGCC
CATGATAGCCTCTTAGATATAATAAATTTGGATTATACTA

>49639_49639_9_LRCH1-PHF11_LRCH1_chr13_47303119_ENST00000389798_PHF11_chr13_50087195_ENST00000488958_length(amino acids)=919AA_BP=660
MPFSPRGERCDPPAGAAGRGGGAREKMATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLNRGLE
RALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ
LSALPACLCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLSLVKFDFSCNK
VLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSLYLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRL
SATEPSDEDTVSLNVPMSNIMEEEQIIKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAEDCEEL
LRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNLYPMGSAEALELQDSALNGQIQLETSPVCEVQSDL
TLQSNGSQYSPNEIRENSPAVSPTTNSTAPFGLKPRSVFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGA
ALMDGVVLCHLVNHIRPRSVASIHVPSPAVLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYH
FFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLK
KCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESDYEEIGSALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCS
FQENRDLMSSSTSISSLSY

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Fusion Gene PPI Analysis for LRCH1-PHF11


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for LRCH1-PHF11


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for LRCH1-PHF11


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneLRCH1C0038454Cerebrovascular accident1CTD_human
HgeneLRCH1C0751956Acute Cerebrovascular Accidents1CTD_human