Fusion Gene Studies
in Kim Lab

FusionBase FusionGDB FusionGDB2 FusionPDB FusionNeoAntigen FusionAI FusionNW FGviewer Publication Contact
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:CIC-ZFP57 (FusionGDB2 ID:HG23152TG346171)

Fusion Gene Summary for CIC-ZFP57

check button Fusion gene summary
Fusion gene informationFusion gene name: CIC-ZFP57
Fusion gene ID: hg23152tg346171
HgeneTgene
Gene symbol

CIC

ZFP57

Gene ID

23152

346171

Gene namecapicua transcriptional repressorZFP57 zinc finger protein
SynonymsMRD45C6orf40|TNDM1|ZNF698|bA145L22|bA145L22.2
Cytomap('CIC')('ZFP57')

19q13.2

6p22.1

Type of geneprotein-codingprotein-coding
Descriptionprotein capicua homologzinc finger protein 57 homologzfp-57zinc finger protein 698
Modification date2020031320200327
UniProtAcc

Q96RK0

.
Ensembl transtripts involved in fusion geneENST00000160740, ENST00000572681, 
ENST00000575354, ENST00000575839, 
Fusion gene scores* DoF score13 X 12 X 6=9362 X 3 X 2=12
# samples 122
** MAII scorelog2(12/936*10)=-2.96347412397489
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/12*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: CIC [Title/Abstract] AND ZFP57 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCIC(42791392)-ZFP57(29641535), # samples:2
Anticipated loss of major functional domain due to fusion event.CIC-ZFP57 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CIC-ZFP57 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CIC-ZFP57 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CIC-ZFP57 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CIC-ZFP57 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
CIC-ZFP57 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CIC-ZFP57 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
CIC-ZFP57 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
CIC-ZFP57 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
CIC-ZFP57 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
CIC-ZFP57 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CIC (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ZFP57 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A1F0-01ACICchr19

42791392

-ZFP57chr6

29641535

-
ChimerDB4BRCATCGA-BH-A1F0-01ACICchr19

42791392

+ZFP57chr6

29641535

-
ChimerDB4BRCATCGA-BH-A1F0-01ACICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-


Top

Fusion Gene ORF analysis for CIC-ZFP57

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000160740ENST00000376881CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000376883CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000383628CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000383628CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000416974CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000416974CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000432222CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000432222CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000435906CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000435906CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000437216CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000437216CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000446005CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000446005CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000448114CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000448114CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000488757CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000547542CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000547542CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000547911CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000547911CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000548001CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000548001CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000548337CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000548337CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000548574CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000548574CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000548769CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000548769CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000549167CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000549167CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000549312CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000549312CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000549501CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000549501CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000552809CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000552809CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000552898CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000552898CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000552987CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000552987CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000160740ENST00000553137CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000160740ENST00000553137CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000376881CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000376883CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000383628CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000383628CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000416974CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000416974CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000432222CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000432222CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000435906CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000435906CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000437216CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000437216CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000446005CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000446005CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000448114CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000448114CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000488757CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000547542CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000547542CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000547911CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000547911CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000548001CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000548001CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000548337CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000548337CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000548574CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000548574CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000548769CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000548769CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000549167CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000549167CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000549312CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000549312CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000549501CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000549501CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000552809CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000552809CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000552898CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000552898CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000552987CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000552987CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000572681ENST00000553137CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000572681ENST00000553137CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000376881CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000376883CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000383628CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000383628CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000416974CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000416974CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000432222CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000432222CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000435906CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000435906CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000437216CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000437216CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000446005CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000446005CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000448114CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000448114CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000488757CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000547542CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000547542CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000547911CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000547911CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000548001CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000548001CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000548337CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000548337CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000548574CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000548574CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000548769CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000548769CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000549167CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000549167CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000549312CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000549312CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000549501CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000549501CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000552809CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000552809CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000552898CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000552898CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000552987CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000552987CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
5CDS-intronENST00000575354ENST00000553137CICchr19

42791392

+ZFP57chr6

29641535

-
5CDS-intronENST00000575354ENST00000553137CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
Frame-shiftENST00000160740ENST00000488757CICchr19

42791392

+ZFP57chr6

29641535

-
Frame-shiftENST00000572681ENST00000488757CICchr19

42791392

+ZFP57chr6

29641535

-
Frame-shiftENST00000575354ENST00000488757CICchr19

42791392

+ZFP57chr6

29641535

-
In-frameENST00000160740ENST00000376881CICchr19

42791392

+ZFP57chr6

29641535

-
In-frameENST00000160740ENST00000376883CICchr19

42791392

+ZFP57chr6

29641535

-
In-frameENST00000572681ENST00000376881CICchr19

42791392

+ZFP57chr6

29641535

-
In-frameENST00000572681ENST00000376883CICchr19

42791392

+ZFP57chr6

29641535

-
In-frameENST00000575354ENST00000376881CICchr19

42791392

+ZFP57chr6

29641535

-
In-frameENST00000575354ENST00000376883CICchr19

42791392

+ZFP57chr6

29641535

-
intron-3CDSENST00000575839ENST00000376881CICchr19

42791392

+ZFP57chr6

29641535

-
intron-3CDSENST00000575839ENST00000376883CICchr19

42791392

+ZFP57chr6

29641535

-
intron-3CDSENST00000575839ENST00000488757CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000376881CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000376883CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000383628CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000383628CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000416974CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000416974CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000432222CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000432222CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000435906CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000435906CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000437216CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000437216CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000446005CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000446005CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000448114CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000448114CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000488757CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000547542CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000547542CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000547911CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000547911CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000548001CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000548001CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000548337CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000548337CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000548574CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000548574CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000548769CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000548769CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000549167CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000549167CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000549312CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000549312CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000549501CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000549501CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000552809CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000552809CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000552898CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000552898CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000552987CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000552987CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-
intron-intronENST00000575839ENST00000553137CICchr19

42791392

+ZFP57chr6

29641535

-
intron-intronENST00000575839ENST00000553137CICchr19

42791392

+ZFP57chr6_cox_hap2

1160337

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000572681CICchr1942791392+ENST00000376881ZFP57chr629641535-461432476832951075
ENST00000572681CICchr1942791392+ENST00000376883ZFP57chr629641535-452332476832951075
ENST00000160740CICchr1942791392+ENST00000376881ZFP57chr629641535-250411378302395521
ENST00000160740CICchr1942791392+ENST00000376883ZFP57chr629641535-241311378302395521
ENST00000575354CICchr1942791392+ENST00000376881ZFP57chr629641535-18594921851750521
ENST00000575354CICchr1942791392+ENST00000376883ZFP57chr629641535-17684921851750521

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000572681ENST00000376881CICchr1942791392+ZFP57chr629641535-0.0037374360.9962625
ENST00000572681ENST00000376883CICchr1942791392+ZFP57chr629641535-0.0041275810.99587244
ENST00000160740ENST00000376881CICchr1942791392+ZFP57chr629641535-0.128885140.87111485
ENST00000160740ENST00000376883CICchr1942791392+ZFP57chr629641535-0.137219520.8627805
ENST00000575354ENST00000376881CICchr1942791392+ZFP57chr629641535-0.144912330.85508764
ENST00000575354ENST00000376883CICchr1942791392+ZFP57chr629641535-0.160950630.8390494

Top

Fusion Genomic Features for CIC-ZFP57


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

Top

Fusion Protein Features for CIC-ZFP57


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:42791392/chr6:29641535)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CIC

Q96RK0

.
FUNCTION: Transcriptional repressor which plays a role in development of the central nervous system (CNS). In concert with ATXN1 and ATXN1L, involved in brain development. {ECO:0000250|UniProtKB:Q924A2}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCICchr19:42791392chr6:29641535ENST00000575354+32042_1381501609.0Compositional biasNote=Pro-rich
TgeneZFP57chr19:42791392chr6:29641535ENST000003836280616_880517.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000004169740616_880517.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000004359060616_880517.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000004372160616_880517.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000004460050616_880517.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000004481140616_880517.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000005475420516_880517.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000005480010516_880517.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000005483370416_880537.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000005485740416_880537.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000005487690416_880537.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000005491670416_880537.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000005493120516_880517.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000005495010516_880517.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000005528090416_880537.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000005528980516_880517.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000005529870516_880517.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000005531370416_880537.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST0000037688135119_14197517.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000037688135147_16997517.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000037688135175_19797517.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000037688135300_32297517.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000037688135328_35097517.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000037688135356_37897517.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST0000037688346119_14197517.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000037688346147_16997517.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000037688346175_19797517.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000037688346300_32297517.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000037688346328_35097517.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000037688346356_37897517.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST0000038362806119_1410517.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000038362806147_1690517.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000038362806175_1970517.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000038362806300_3220517.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000038362806328_3500517.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000038362806356_3780517.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000003836280691_1130517.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST0000041697406119_1410517.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000041697406147_1690517.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000041697406175_1970517.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000041697406300_3220517.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000041697406328_3500517.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000041697406356_3780517.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000004169740691_1130517.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST0000043590606119_1410517.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000043590606147_1690517.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000043590606175_1970517.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000043590606300_3220517.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000043590606328_3500517.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000043590606356_3780517.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000004359060691_1130517.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST0000043721606119_1410517.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000043721606147_1690517.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000043721606175_1970517.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000043721606300_3220517.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000043721606328_3500517.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000043721606356_3780517.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000004372160691_1130517.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST0000044600506119_1410517.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000044600506147_1690517.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000044600506175_1970517.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000044600506300_3220517.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000044600506328_3500517.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000044600506356_3780517.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000004460050691_1130517.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST0000044811406119_1410517.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000044811406147_1690517.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000044811406175_1970517.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000044811406300_3220517.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000044811406328_3500517.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000044811406356_3780517.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000004481140691_1130517.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST0000048875724119_141117537.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000048875724147_169117537.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000048875724175_197117537.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000048875724300_322117537.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000048875724328_350117537.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000048875724356_378117537.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST0000054754205119_1410517.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000054754205147_1690517.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000054754205175_1970517.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000054754205300_3220517.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000054754205328_3500517.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000054754205356_3780517.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000005475420591_1130517.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST0000054800105119_1410517.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000054800105147_1690517.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000054800105175_1970517.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000054800105300_3220517.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000054800105328_3500517.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000054800105356_3780517.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000005480010591_1130517.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST0000054833704119_1410537.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000054833704147_1690537.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000054833704175_1970537.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000054833704300_3220537.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000054833704328_3500537.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000054833704356_3780537.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000005483370491_1130537.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST0000054857404119_1410537.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000054857404147_1690537.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000054857404175_1970537.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000054857404300_3220537.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000054857404328_3500537.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000054857404356_3780537.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000005485740491_1130537.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST0000054876904119_1410537.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000054876904147_1690537.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000054876904175_1970537.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000054876904300_3220537.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000054876904328_3500537.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000054876904356_3780537.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000005487690491_1130537.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST0000054916704119_1410537.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000054916704147_1690537.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000054916704175_1970537.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000054916704300_3220537.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000054916704328_3500537.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000054916704356_3780537.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000005491670491_1130537.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST0000054931205119_1410517.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000054931205147_1690517.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000054931205175_1970517.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000054931205300_3220517.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000054931205328_3500517.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000054931205356_3780517.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000005493120591_1130517.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST0000054950105119_1410517.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000054950105147_1690517.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000054950105175_1970517.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000054950105300_3220517.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000054950105328_3500517.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000054950105356_3780517.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000005495010591_1130517.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST0000055280904119_1410537.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000055280904147_1690537.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000055280904175_1970537.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000055280904300_3220537.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000055280904328_3500537.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000055280904356_3780537.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000005528090491_1130537.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST0000055289805119_1410517.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000055289805147_1690517.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000055289805175_1970517.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000055289805300_3220517.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000055289805328_3500517.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000055289805356_3780517.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000005528980591_1130517.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST0000055298705119_1410517.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000055298705147_1690517.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000055298705175_1970517.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000055298705300_3220517.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000055298705328_3500517.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000055298705356_3780517.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000005529870591_1130517.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST0000055313704119_1410537.0Zinc fingerC2H2-type 2
TgeneZFP57chr19:42791392chr6:29641535ENST0000055313704147_1690537.0Zinc fingerC2H2-type 3
TgeneZFP57chr19:42791392chr6:29641535ENST0000055313704175_1970537.0Zinc fingerC2H2-type 4
TgeneZFP57chr19:42791392chr6:29641535ENST0000055313704300_3220537.0Zinc fingerC2H2-type 5
TgeneZFP57chr19:42791392chr6:29641535ENST0000055313704328_3500537.0Zinc fingerC2H2-type 6
TgeneZFP57chr19:42791392chr6:29641535ENST0000055313704356_3780537.0Zinc fingerC2H2-type 7%3B degenerate
TgeneZFP57chr19:42791392chr6:29641535ENST000005531370491_1130537.0Zinc fingerC2H2-type 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCICchr19:42791392chr6:29641535ENST00000575354+3201524_16011501609.0Compositional biasNote=Pro-rich
HgeneCICchr19:42791392chr6:29641535ENST00000575354+320508_13031501609.0Compositional biasNote=Pro-rich
HgeneCICchr19:42791392chr6:29641535ENST00000575354+320200_2681501609.0DNA bindingHMG box
TgeneZFP57chr19:42791392chr6:29641535ENST000003768813516_8897517.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000003768834616_8897517.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000004887572416_88117537.0DomainKRAB
TgeneZFP57chr19:42791392chr6:29641535ENST000003768813591_11397517.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST000003768834691_11397517.0Zinc fingerC2H2-type 1
TgeneZFP57chr19:42791392chr6:29641535ENST000004887572491_113117537.0Zinc fingerC2H2-type 1


Top

Fusion Gene Sequence for CIC-ZFP57


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>16804_16804_1_CIC-ZFP57_CIC_chr19_42791392_ENST00000160740_ZFP57_chr6_29641535_ENST00000376881_length(transcript)=2504nt_BP=1137nt
GGGGGAGGCGCGGCGGGGGGAGGGGAGCGCGTAGTAGTGGCGGGGCGGGGAGGCGGTGGTGGTTCGGCGCGGGGCTCGCTCGGAGCGCAC
GGACGCACGCACGCTGGTCCGTCTGCCCGCCCGGGGCCGGAGGTCGACCCGGCGCTGAGCCTCGGGCCCGGGGCCCGGAAAGGCGGGGCG
GCGGCGCCGGCAGCCGGGACGCGCGGGGCCAGAGCCGTTACCCGCCGGAGCTGCGAGGGAGGGAGGGAACGAGCGAGCCAGCGAGCGGGG
AAGGGAGGGGGCCGCCCCCGCGCACGCGCGTCGCGCCCCGCCCCGCCTGCCCCGCCTGCCCCGCCCGCCGGACTCCGCGAGGGAGGAGGG
AGAGGGAGGGGGCGGTGCCGATGGCCCCCGTGCCGCGCGCCCCGTGACGGCCCCCGCGCGCGCCGGGGGGCGGGGCGGGGCCGGTGCGCG
CTGACCTCCCCCGCCCCCCGGGCGGCGGGAGGCAGGCGGCGCTGTGCGCAGGCGCGCCCGGCAGAGACCCCCGCGTGGGGCGGCCGGAGG
GGGGCGGCGGGGGGGGGGGCATGCGGCGACGGCCTCCCGCTCCCCCCGGGCCCAAGCGGCGACGGCCGAGGAGCGGGCTGCGGGCGGAGC
GGCGTCGGCCGCTGAGGAGGTGCGAGCCCCTGCCGGGTCCCCCCTGCGCCGGACCATGTATTCGGCCCACAGGCCCCTGATGCCCGCGTC
CAGCGCGGCCTCCCGTGGCCTCGGCATGTTCGTGTGGACGAATGTGGAACCTCGCTCTGTGGCTGTGTTCCCTTGGCACTCCTTAGTCCC
CTTCCTGGCACCCAGCCAGCCTGACCCCTCCGTGCAGCCGAGCGAGGCCCAGCAACCTGCCAGCCACCCAGTGGCCTCCAACCAGAGCAA
AGAACCTGCTGAGTCGGCAGCTGTTGCTCATGAACGGCCACCAGGTGGGACAGGGAGTGCTGACCCTGAGCGGCCCCCTGGAGCCACATG
CCCTGAGAGCCCAGGACCCGGACCCCCACACCCTTTGGGGGTGGTGGAATCTGGTAAGGGTCCGCCTCCCACCACGGAGGAGGAGGCCTC
CGGCCCCCCAGGAGAGCCCCGGCTGGACAGTGAGACAGAGAGTGACCATGATGATGCAAGGCAAGAAGAAAGAGCTTCGAGAACAACATC
CCAGTCTGAGAGATGAGGGGACTAGTGATGACAAGGTCTTCCTTGCATGCAGAGGGGCCGGCCAGTGCCCCCTATCTGCCCCAGCTGGGA
CTATGGACAGGACCCGGGTGCTTCAAGCATCCCAGGCTGGGCCACCCTTTTTTTGCTACACCTGTGGCAAATGTTTCAGCAGGCGCTCCT
ACCTCTATAGCCACCAGTTTGTTCACAATCCCAAGCTGACTAACAGCTGCAGTCAGTGTGGGAAGTTGTTTCGGAGCCCCAAGTCCCTCA
GCTATCACAGACGCATGCATCTTGGGGAGAGGCCCTTCTGTTGCACGCTCTGTGACAAGACCTACTGTGATGCTTCTGGACTAAGTCGTC
ACCGCCGCGTCCATCTGGGTTACCGGCCCCATTCATGCTCTGTGTGTGGGAAGAGCTTCCGGGACCAGTCTGAGCTCAAACGCCACCAGA
AGATACACCAAAACCAGGAGCCAGTGGATGGAAACCAGGAGTGTACTTTGAGGATTCCAGGCACCCAGGCTGAATTCCAGACACCCATCG
CCAGAAGCCAGAGGTCCATCCAGGGGCTTTTGGATGTGAACCATGCACCAGTGGCCAGGTCCCAGGAACCCATATTTAGAACTGAGGGTC
CTATGGCCCAGAACCAGGCATCTGTACTTAAGAACCAAGCACCTGTGACCAGGACCCAGGCACCCATCACTGGAACCCTCTGTCAGGATG
CCAGATCCAACTCTCATCCAGTGAAGCCCTCAAGACTCAATGTCTTCTGTTGCCCCCATTGTTCTTTGACTTTTAGCAAGAAATCCTATC
TCTCCAGACACCAGAAGGCCCACCTCACAGAGCCGCCCAACTACTGCTTCCATTGCAGCAAGTCTTTCAGCTCATTTTCCAGGCTGGTCA
GACACCAGCAGACCCACTGGAAGCAGAAGAGCTACCTTTGCCCTATCTGTGACCTCTCCTTTGGGGAGAAAGAGGGCCTTATGGATCACT
GGAGGGGCTATAAAGGCAAGGACCTGTGCCAGAGCAGCCACCATAAATGCCGGGTGATCCTGGGCCAGTGGCTTGGCTTCTCTCATGATG
TCCCCACTATGGCTGGGGAGGAATGGAAGCATGGAGGTGATCAATCTCCCCCCAGGATCCATACCCCCAGGAGAAGAGGCCTAAGAGAGA
AGGCCTGCAAAGGAGACAAAACAAAGGAGGCAGTGAGCATCTTGAAACATAAATAAATGGCCTTTCTGACTGAGCTCTTTCTTTGTGTTT
AGTTTTCCTGAGGACTGACCTCTGGGGTAATGAGGCTGGAGTAGAGGGAGACAGGTGCGTGGATAAGGAAGGAA

>16804_16804_1_CIC-ZFP57_CIC_chr19_42791392_ENST00000160740_ZFP57_chr6_29641535_ENST00000376881_length(amino acids)=521AA_BP=103
MTPPCSRARPSNLPATQWPPTRAKNLLSRQLLLMNGHQVGQGVLTLSGPLEPHALRAQDPDPHTLWGWWNLVRVRLPPRRRRPPAPQESP
GWTVRQRVTMMMQGKKKELREQHPSLRDEGTSDDKVFLACRGAGQCPLSAPAGTMDRTRVLQASQAGPPFFCYTCGKCFSRRSYLYSHQF
VHNPKLTNSCSQCGKLFRSPKSLSYHRRMHLGERPFCCTLCDKTYCDASGLSRHRRVHLGYRPHSCSVCGKSFRDQSELKRHQKIHQNQE
PVDGNQECTLRIPGTQAEFQTPIARSQRSIQGLLDVNHAPVARSQEPIFRTEGPMAQNQASVLKNQAPVTRTQAPITGTLCQDARSNSHP
VKPSRLNVFCCPHCSLTFSKKSYLSRHQKAHLTEPPNYCFHCSKSFSSFSRLVRHQQTHWKQKSYLCPICDLSFGEKEGLMDHWRGYKGK
DLCQSSHHKCRVILGQWLGFSHDVPTMAGEEWKHGGDQSPPRIHTPRRRGLREKACKGDKTKEAVSILKHK

--------------------------------------------------------------
>16804_16804_2_CIC-ZFP57_CIC_chr19_42791392_ENST00000160740_ZFP57_chr6_29641535_ENST00000376883_length(transcript)=2413nt_BP=1137nt
GGGGGAGGCGCGGCGGGGGGAGGGGAGCGCGTAGTAGTGGCGGGGCGGGGAGGCGGTGGTGGTTCGGCGCGGGGCTCGCTCGGAGCGCAC
GGACGCACGCACGCTGGTCCGTCTGCCCGCCCGGGGCCGGAGGTCGACCCGGCGCTGAGCCTCGGGCCCGGGGCCCGGAAAGGCGGGGCG
GCGGCGCCGGCAGCCGGGACGCGCGGGGCCAGAGCCGTTACCCGCCGGAGCTGCGAGGGAGGGAGGGAACGAGCGAGCCAGCGAGCGGGG
AAGGGAGGGGGCCGCCCCCGCGCACGCGCGTCGCGCCCCGCCCCGCCTGCCCCGCCTGCCCCGCCCGCCGGACTCCGCGAGGGAGGAGGG
AGAGGGAGGGGGCGGTGCCGATGGCCCCCGTGCCGCGCGCCCCGTGACGGCCCCCGCGCGCGCCGGGGGGCGGGGCGGGGCCGGTGCGCG
CTGACCTCCCCCGCCCCCCGGGCGGCGGGAGGCAGGCGGCGCTGTGCGCAGGCGCGCCCGGCAGAGACCCCCGCGTGGGGCGGCCGGAGG
GGGGCGGCGGGGGGGGGGGCATGCGGCGACGGCCTCCCGCTCCCCCCGGGCCCAAGCGGCGACGGCCGAGGAGCGGGCTGCGGGCGGAGC
GGCGTCGGCCGCTGAGGAGGTGCGAGCCCCTGCCGGGTCCCCCCTGCGCCGGACCATGTATTCGGCCCACAGGCCCCTGATGCCCGCGTC
CAGCGCGGCCTCCCGTGGCCTCGGCATGTTCGTGTGGACGAATGTGGAACCTCGCTCTGTGGCTGTGTTCCCTTGGCACTCCTTAGTCCC
CTTCCTGGCACCCAGCCAGCCTGACCCCTCCGTGCAGCCGAGCGAGGCCCAGCAACCTGCCAGCCACCCAGTGGCCTCCAACCAGAGCAA
AGAACCTGCTGAGTCGGCAGCTGTTGCTCATGAACGGCCACCAGGTGGGACAGGGAGTGCTGACCCTGAGCGGCCCCCTGGAGCCACATG
CCCTGAGAGCCCAGGACCCGGACCCCCACACCCTTTGGGGGTGGTGGAATCTGGTAAGGGTCCGCCTCCCACCACGGAGGAGGAGGCCTC
CGGCCCCCCAGGAGAGCCCCGGCTGGACAGTGAGACAGAGAGTGACCATGATGATGCAAGGCAAGAAGAAAGAGCTTCGAGAACAACATC
CCAGTCTGAGAGATGAGGGGACTAGTGATGACAAGGTCTTCCTTGCATGCAGAGGGGCCGGCCAGTGCCCCCTATCTGCCCCAGCTGGGA
CTATGGACAGGACCCGGGTGCTTCAAGCATCCCAGGCTGGGCCACCCTTTTTTTGCTACACCTGTGGCAAATGTTTCAGCAGGCGCTCCT
ACCTCTATAGCCACCAGTTTGTTCACAATCCCAAGCTGACTAACAGCTGCAGTCAGTGTGGGAAGTTGTTTCGGAGCCCCAAGTCCCTCA
GCTATCACAGACGCATGCATCTTGGGGAGAGGCCCTTCTGTTGCACGCTCTGTGACAAGACCTACTGTGATGCTTCTGGACTAAGTCGTC
ACCGCCGCGTCCATCTGGGTTACCGGCCCCATTCATGCTCTGTGTGTGGGAAGAGCTTCCGGGACCAGTCTGAGCTCAAACGCCACCAGA
AGATACACCAAAACCAGGAGCCAGTGGATGGAAACCAGGAGTGTACTTTGAGGATTCCAGGCACCCAGGCTGAATTCCAGACACCCATCG
CCAGAAGCCAGAGGTCCATCCAGGGGCTTTTGGATGTGAACCATGCACCAGTGGCCAGGTCCCAGGAACCCATATTTAGAACTGAGGGTC
CTATGGCCCAGAACCAGGCATCTGTACTTAAGAACCAAGCACCTGTGACCAGGACCCAGGCACCCATCACTGGAACCCTCTGTCAGGATG
CCAGATCCAACTCTCATCCAGTGAAGCCCTCAAGACTCAATGTCTTCTGTTGCCCCCATTGTTCTTTGACTTTTAGCAAGAAATCCTATC
TCTCCAGACACCAGAAGGCCCACCTCACAGAGCCGCCCAACTACTGCTTCCATTGCAGCAAGTCTTTCAGCTCATTTTCCAGGCTGGTCA
GACACCAGCAGACCCACTGGAAGCAGAAGAGCTACCTTTGCCCTATCTGTGACCTCTCCTTTGGGGAGAAAGAGGGCCTTATGGATCACT
GGAGGGGCTATAAAGGCAAGGACCTGTGCCAGAGCAGCCACCATAAATGCCGGGTGATCCTGGGCCAGTGGCTTGGCTTCTCTCATGATG
TCCCCACTATGGCTGGGGAGGAATGGAAGCATGGAGGTGATCAATCTCCCCCCAGGATCCATACCCCCAGGAGAAGAGGCCTAAGAGAGA
AGGCCTGCAAAGGAGACAAAACAAAGGAGGCAGTGAGCATCTTGAAACATAAATAAATGGCCTTTCTGACTGA

>16804_16804_2_CIC-ZFP57_CIC_chr19_42791392_ENST00000160740_ZFP57_chr6_29641535_ENST00000376883_length(amino acids)=521AA_BP=103
MTPPCSRARPSNLPATQWPPTRAKNLLSRQLLLMNGHQVGQGVLTLSGPLEPHALRAQDPDPHTLWGWWNLVRVRLPPRRRRPPAPQESP
GWTVRQRVTMMMQGKKKELREQHPSLRDEGTSDDKVFLACRGAGQCPLSAPAGTMDRTRVLQASQAGPPFFCYTCGKCFSRRSYLYSHQF
VHNPKLTNSCSQCGKLFRSPKSLSYHRRMHLGERPFCCTLCDKTYCDASGLSRHRRVHLGYRPHSCSVCGKSFRDQSELKRHQKIHQNQE
PVDGNQECTLRIPGTQAEFQTPIARSQRSIQGLLDVNHAPVARSQEPIFRTEGPMAQNQASVLKNQAPVTRTQAPITGTLCQDARSNSHP
VKPSRLNVFCCPHCSLTFSKKSYLSRHQKAHLTEPPNYCFHCSKSFSSFSRLVRHQQTHWKQKSYLCPICDLSFGEKEGLMDHWRGYKGK
DLCQSSHHKCRVILGQWLGFSHDVPTMAGEEWKHGGDQSPPRIHTPRRRGLREKACKGDKTKEAVSILKHK

--------------------------------------------------------------
>16804_16804_3_CIC-ZFP57_CIC_chr19_42791392_ENST00000572681_ZFP57_chr6_29641535_ENST00000376881_length(transcript)=4614nt_BP=3247nt
GTGCCGCTACCGCTGCCACTGAGAGGAGCCACCGGCGACGCCAGAGCCAGGAATACGGGTGGACAAAAATGAAGCCAATGAAGAAGGCAT
GCACTGGCCTTTCAGGTCCTGGCAGTGGCAGCAAGTCCCCCCCAGCCACCAGGGCCAAGGCTCTGAGGCGGCGAGGGGCTGGGGAGGGTG
ACAAGCCAGAGGAGGAGGATGACGAGGCACAGCAGCCGCAACCACAGTCCGGGCCCGAAGAGGCTGAGGAAGGGGAGGAGGAGGAGGCTG
AGCGGGGCCCTGGGGCTGAAGGTCCTCCACTGGAGCTGCACCCTGGCGACCCGGCTCCAGGCCCAGCAGAGGACCCCAAAGGGGATGGGG
AGGCAGGCCGCTGGGAGCCCTCACTCAGCCGCAAGACAGCCACGTTCAAGTCTCGAGCGCCCAAGAAGAAGTATGTGGAGGAGCACGGAG
CTGGCAGCAGTGGGGTGGCTGGGGCCCCTGAAGAGCGGGTGCGGACCCCTGAGGAGGCCAGTGGCCTGGGGGTGCCTCCACGGCCACCCA
CCTCCACTCGTTCCTCCTCCACTGACACAGCCAGCGAGCACTCGGCGGACCTGGAGGATGAGCCGGCTGAGGCTTGTGGTCCAGGCCCTT
GGCCCCCTGGCAGCACCAGTGGCAGCTATGACCTGCGGCAGCTGCGGTCCCAGCGGGTGCTGGCTCGGCGTGGTGATGGCCTTTTCCTGC
CGGCTGTGGTGCGCCAGGTGCGCCGAAGCCAGGACCTGGGCGTGCAGTTCCCTGGTGACCGAGCCCTGACTTTCTATGAGGGGGTGCCAG
GCGCTGGTGTGGATGTAGTTTTGGATGCCACACCCCCACCAGGTGCCCTGGTGGTGGGCACAGCTGTCTGTACCTGTGTGGAGCCCGGCG
TGGCTGCCTACCGGGAAGGTGTGGTGGTGGAGGTGGCCACCAAGCCAGCTGCCTACAAGGTCCGTCTCAGCCCTGGCCCCAGCTCCCAGC
CAGGCCTACCAGGCAGCCTCCCGCAGCCCCCACAGCCACTGCACCGTGAGCCAGAGGAGGCTGTGTGGGTGGCCCGCTCCAGCCTACGCC
TGCTGCGCCCCCCCTGGGAACCTGAGACCATGCTGAGGAAGCCCCCTACAGGCCCTGAGGAAGAGCAGGCAGAGCCTGGGGCCACCCTGC
CACCCTGCCCTGCTGCCCTGGACCCCAAACAGCCCGAGGATGCTGAGGTCTCTAAGATCAGCTTTGGTGGCAACCTGGGTACTCACTGTG
AGGAGGGCGAGGAGAAGCACCCTCCAGCCCTGGGTACCCCAGCCCTGCTCCCACTGCCCCCACCCCAGCTCCTGTCACCACCACCCAAGT
CTCCAGCCTTTGTGGGCCCCGGCCGCCCTGGCGAGCAGCCCTCGCCCTGCCAGGAGGGGAGCCAGGGCGGCAGCCGCAGCAGCAGCGTGG
CCTCCCTGGAAAAGGGGACAGCACCGGCAGCCCGGGCCCGCACGCCACTGACAGCCGCCCAGCAGAAGTACAAGAAGGGCGATGTGGTCT
GCACACCCAGCGGAATACGAAAGAAGTTCAACGGCAAGCAGTGGCGCCGGCTGTGCTCACGAGATGGCTGCATGAAGGAGTCACAGCGGC
GAGGCTACTGCTCACGCCACCTGTCCATGCGAACCAAAGAGATGGAAGGCCTGGCAGACAGTGGGCCTGGCGGGGCGGGCCGGCCCGCGG
CCGTGGCAGCCCGTGAGGGCAGCACGGAGTTTGACTGGGGTGATGAGACGTCGAGGGACAGTGAGGCCAGCAGTGTGGCGGCTCGTGGAG
ACTCACGGCCACGCCTGGTGGCCCCTGCTGACTTGTCACGCTTTGAGTTCGACGAGTGTGAGGCGGCCGTGATGCTGGTGTCGCTGGGCA
GCTCGCGCTCAGGCACGCCCTCCTTCTCACCCGTCTCCACTCAATCGCCCTTCTCGCCAGCCCCATCACCCTCACCCTCACCACTCTTCG
GCTTCCGCCCTGCCAACTTTAGCCCCATCAATGCCTCACCAGTCATCCAGCGCACTGCAGTCCGCAGTCGCCACCTGAGCGCCAGCACCC
CTAAGGCAGGCGTGCTGACGCCACCAGACCTGGGCCCCCACCCACCGCCACCTGCCCCCCGAGAGCGCCACTCCTCTGGAATCCTACCCA
CCTTCCAGACCAACCTGACCTTCACCGTGCCCATCAGCCCTGGGCGACGGAAGACAGAGCTGTTGCCGCATCCAGGGGCCTTGGGGGCCC
CTGGCGCAGGGGGTGGAGGAGCCGCCCCAGACTTTCCCAAGAGTGACAGCTTAGACTCTGGTGTGGACTCAGTGTCCCACACACCTACAC
CCTCCACGCCGGCTGGCTTCCGGGCCGTGTCCCCTGCTGTGCCCTTCTCTCGCTCCCGCCAGCCCTCACCATTGCTGCTGTTGCCACCCC
CTGCCGGCCTGACCTCGGATCCAGGGCCCTCTGTGCGCAGGGTGCCTGCTGTGCAGCGGGACTCACCTGTTATTGTCCGCAACCCTGATG
TGCCACTGCCCTCCAAATTCCCTGGGGAGGTGGGCACTGCTGGTGAGGTGCGGGCTGGGGGACCTGGGCGGGGCTGCCGTGAAACCCCAG
TGCCCCCTGGGGTGGCCAGTGGGAAGCCTGGCCTGCCCCCACCTCTGCCAGCCCCCGTGCCCATCACCGTGCCTCCAGCTGCACCAACTG
CCGTGGCCCAGCCGATGCCCGCCTTTGGCCTGGCTTCTTCACCCTTTCAGCCTGTGGCCTTCCACCCCTCACCTGCTGCCCTGTTGCCCG
TTTTGGTGCCCAGCAGCTATACCAGCCACCCTGCCCCCAAGAAGGAAGTCATCATGGGCCGGCCTGGAACAGTGTGGACGAATGTGGAAC
CTCGCTCTGTGGCTGTGTTCCCTTGGCACTCCTTAGTCCCCTTCCTGGCACCCAGCCAGCCTGACCCCTCCGTGCAGCCGAGCGAGGCCC
AGCAACCTGCCAGCCACCCAGTGGCCTCCAACCAGAGCAAAGAACCTGCTGAGTCGGCAGCTGTTGCTCATGAACGGCCACCAGGTGGGA
CAGGGAGTGCTGACCCTGAGCGGCCCCCTGGAGCCACATGCCCTGAGAGCCCAGGACCCGGACCCCCACACCCTTTGGGGGTGGTGGAAT
CTGGTAAGGGTCCGCCTCCCACCACGGAGGAGGAGGCCTCCGGCCCCCCAGGAGAGCCCCGGCTGGACAGTGAGACAGAGAGTGACCATG
ATGATGCAAGGCAAGAAGAAAGAGCTTCGAGAACAACATCCCAGTCTGAGAGATGAGGGGACTAGTGATGACAAGGTCTTCCTTGCATGC
AGAGGGGCCGGCCAGTGCCCCCTATCTGCCCCAGCTGGGACTATGGACAGGACCCGGGTGCTTCAAGCATCCCAGGCTGGGCCACCCTTT
TTTTGCTACACCTGTGGCAAATGTTTCAGCAGGCGCTCCTACCTCTATAGCCACCAGTTTGTTCACAATCCCAAGCTGACTAACAGCTGC
AGTCAGTGTGGGAAGTTGTTTCGGAGCCCCAAGTCCCTCAGCTATCACAGACGCATGCATCTTGGGGAGAGGCCCTTCTGTTGCACGCTC
TGTGACAAGACCTACTGTGATGCTTCTGGACTAAGTCGTCACCGCCGCGTCCATCTGGGTTACCGGCCCCATTCATGCTCTGTGTGTGGG
AAGAGCTTCCGGGACCAGTCTGAGCTCAAACGCCACCAGAAGATACACCAAAACCAGGAGCCAGTGGATGGAAACCAGGAGTGTACTTTG
AGGATTCCAGGCACCCAGGCTGAATTCCAGACACCCATCGCCAGAAGCCAGAGGTCCATCCAGGGGCTTTTGGATGTGAACCATGCACCA
GTGGCCAGGTCCCAGGAACCCATATTTAGAACTGAGGGTCCTATGGCCCAGAACCAGGCATCTGTACTTAAGAACCAAGCACCTGTGACC
AGGACCCAGGCACCCATCACTGGAACCCTCTGTCAGGATGCCAGATCCAACTCTCATCCAGTGAAGCCCTCAAGACTCAATGTCTTCTGT
TGCCCCCATTGTTCTTTGACTTTTAGCAAGAAATCCTATCTCTCCAGACACCAGAAGGCCCACCTCACAGAGCCGCCCAACTACTGCTTC
CATTGCAGCAAGTCTTTCAGCTCATTTTCCAGGCTGGTCAGACACCAGCAGACCCACTGGAAGCAGAAGAGCTACCTTTGCCCTATCTGT
GACCTCTCCTTTGGGGAGAAAGAGGGCCTTATGGATCACTGGAGGGGCTATAAAGGCAAGGACCTGTGCCAGAGCAGCCACCATAAATGC
CGGGTGATCCTGGGCCAGTGGCTTGGCTTCTCTCATGATGTCCCCACTATGGCTGGGGAGGAATGGAAGCATGGAGGTGATCAATCTCCC
CCCAGGATCCATACCCCCAGGAGAAGAGGCCTAAGAGAGAAGGCCTGCAAAGGAGACAAAACAAAGGAGGCAGTGAGCATCTTGAAACAT
AAATAAATGGCCTTTCTGACTGAGCTCTTTCTTTGTGTTTAGTTTTCCTGAGGACTGACCTCTGGGGTAATGAGGCTGGAGTAGAGGGAG
ACAGGTGCGTGGATAAGGAAGGAA

>16804_16804_3_CIC-ZFP57_CIC_chr19_42791392_ENST00000572681_ZFP57_chr6_29641535_ENST00000376881_length(amino acids)=1075AA_BP=1060
MKPMKKACTGLSGPGSGSKSPPATRAKALRRRGAGEGDKPEEEDDEAQQPQPQSGPEEAEEGEEEEAERGPGAEGPPLELHPGDPAPGPA
EDPKGDGEAGRWEPSLSRKTATFKSRAPKKKYVEEHGAGSSGVAGAPEERVRTPEEASGLGVPPRPPTSTRSSSTDTASEHSADLEDEPA
EACGPGPWPPGSTSGSYDLRQLRSQRVLARRGDGLFLPAVVRQVRRSQDLGVQFPGDRALTFYEGVPGAGVDVVLDATPPPGALVVGTAV
CTCVEPGVAAYREGVVVEVATKPAAYKVRLSPGPSSQPGLPGSLPQPPQPLHREPEEAVWVARSSLRLLRPPWEPETMLRKPPTGPEEEQ
AEPGATLPPCPAALDPKQPEDAEVSKISFGGNLGTHCEEGEEKHPPALGTPALLPLPPPQLLSPPPKSPAFVGPGRPGEQPSPCQEGSQG
GSRSSSVASLEKGTAPAARARTPLTAAQQKYKKGDVVCTPSGIRKKFNGKQWRRLCSRDGCMKESQRRGYCSRHLSMRTKEMEGLADSGP
GGAGRPAAVAAREGSTEFDWGDETSRDSEASSVAARGDSRPRLVAPADLSRFEFDECEAAVMLVSLGSSRSGTPSFSPVSTQSPFSPAPS
PSPSPLFGFRPANFSPINASPVIQRTAVRSRHLSASTPKAGVLTPPDLGPHPPPPAPRERHSSGILPTFQTNLTFTVPISPGRRKTELLP
HPGALGAPGAGGGGAAPDFPKSDSLDSGVDSVSHTPTPSTPAGFRAVSPAVPFSRSRQPSPLLLLPPPAGLTSDPGPSVRRVPAVQRDSP
VIVRNPDVPLPSKFPGEVGTAGEVRAGGPGRGCRETPVPPGVASGKPGLPPPLPAPVPITVPPAAPTAVAQPMPAFGLASSPFQPVAFHP
SPAALLPVLVPSSYTSHPAPKKEVIMGRPGTVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVA
HERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDARQEERASRTTSQSER

--------------------------------------------------------------
>16804_16804_4_CIC-ZFP57_CIC_chr19_42791392_ENST00000572681_ZFP57_chr6_29641535_ENST00000376883_length(transcript)=4523nt_BP=3247nt
GTGCCGCTACCGCTGCCACTGAGAGGAGCCACCGGCGACGCCAGAGCCAGGAATACGGGTGGACAAAAATGAAGCCAATGAAGAAGGCAT
GCACTGGCCTTTCAGGTCCTGGCAGTGGCAGCAAGTCCCCCCCAGCCACCAGGGCCAAGGCTCTGAGGCGGCGAGGGGCTGGGGAGGGTG
ACAAGCCAGAGGAGGAGGATGACGAGGCACAGCAGCCGCAACCACAGTCCGGGCCCGAAGAGGCTGAGGAAGGGGAGGAGGAGGAGGCTG
AGCGGGGCCCTGGGGCTGAAGGTCCTCCACTGGAGCTGCACCCTGGCGACCCGGCTCCAGGCCCAGCAGAGGACCCCAAAGGGGATGGGG
AGGCAGGCCGCTGGGAGCCCTCACTCAGCCGCAAGACAGCCACGTTCAAGTCTCGAGCGCCCAAGAAGAAGTATGTGGAGGAGCACGGAG
CTGGCAGCAGTGGGGTGGCTGGGGCCCCTGAAGAGCGGGTGCGGACCCCTGAGGAGGCCAGTGGCCTGGGGGTGCCTCCACGGCCACCCA
CCTCCACTCGTTCCTCCTCCACTGACACAGCCAGCGAGCACTCGGCGGACCTGGAGGATGAGCCGGCTGAGGCTTGTGGTCCAGGCCCTT
GGCCCCCTGGCAGCACCAGTGGCAGCTATGACCTGCGGCAGCTGCGGTCCCAGCGGGTGCTGGCTCGGCGTGGTGATGGCCTTTTCCTGC
CGGCTGTGGTGCGCCAGGTGCGCCGAAGCCAGGACCTGGGCGTGCAGTTCCCTGGTGACCGAGCCCTGACTTTCTATGAGGGGGTGCCAG
GCGCTGGTGTGGATGTAGTTTTGGATGCCACACCCCCACCAGGTGCCCTGGTGGTGGGCACAGCTGTCTGTACCTGTGTGGAGCCCGGCG
TGGCTGCCTACCGGGAAGGTGTGGTGGTGGAGGTGGCCACCAAGCCAGCTGCCTACAAGGTCCGTCTCAGCCCTGGCCCCAGCTCCCAGC
CAGGCCTACCAGGCAGCCTCCCGCAGCCCCCACAGCCACTGCACCGTGAGCCAGAGGAGGCTGTGTGGGTGGCCCGCTCCAGCCTACGCC
TGCTGCGCCCCCCCTGGGAACCTGAGACCATGCTGAGGAAGCCCCCTACAGGCCCTGAGGAAGAGCAGGCAGAGCCTGGGGCCACCCTGC
CACCCTGCCCTGCTGCCCTGGACCCCAAACAGCCCGAGGATGCTGAGGTCTCTAAGATCAGCTTTGGTGGCAACCTGGGTACTCACTGTG
AGGAGGGCGAGGAGAAGCACCCTCCAGCCCTGGGTACCCCAGCCCTGCTCCCACTGCCCCCACCCCAGCTCCTGTCACCACCACCCAAGT
CTCCAGCCTTTGTGGGCCCCGGCCGCCCTGGCGAGCAGCCCTCGCCCTGCCAGGAGGGGAGCCAGGGCGGCAGCCGCAGCAGCAGCGTGG
CCTCCCTGGAAAAGGGGACAGCACCGGCAGCCCGGGCCCGCACGCCACTGACAGCCGCCCAGCAGAAGTACAAGAAGGGCGATGTGGTCT
GCACACCCAGCGGAATACGAAAGAAGTTCAACGGCAAGCAGTGGCGCCGGCTGTGCTCACGAGATGGCTGCATGAAGGAGTCACAGCGGC
GAGGCTACTGCTCACGCCACCTGTCCATGCGAACCAAAGAGATGGAAGGCCTGGCAGACAGTGGGCCTGGCGGGGCGGGCCGGCCCGCGG
CCGTGGCAGCCCGTGAGGGCAGCACGGAGTTTGACTGGGGTGATGAGACGTCGAGGGACAGTGAGGCCAGCAGTGTGGCGGCTCGTGGAG
ACTCACGGCCACGCCTGGTGGCCCCTGCTGACTTGTCACGCTTTGAGTTCGACGAGTGTGAGGCGGCCGTGATGCTGGTGTCGCTGGGCA
GCTCGCGCTCAGGCACGCCCTCCTTCTCACCCGTCTCCACTCAATCGCCCTTCTCGCCAGCCCCATCACCCTCACCCTCACCACTCTTCG
GCTTCCGCCCTGCCAACTTTAGCCCCATCAATGCCTCACCAGTCATCCAGCGCACTGCAGTCCGCAGTCGCCACCTGAGCGCCAGCACCC
CTAAGGCAGGCGTGCTGACGCCACCAGACCTGGGCCCCCACCCACCGCCACCTGCCCCCCGAGAGCGCCACTCCTCTGGAATCCTACCCA
CCTTCCAGACCAACCTGACCTTCACCGTGCCCATCAGCCCTGGGCGACGGAAGACAGAGCTGTTGCCGCATCCAGGGGCCTTGGGGGCCC
CTGGCGCAGGGGGTGGAGGAGCCGCCCCAGACTTTCCCAAGAGTGACAGCTTAGACTCTGGTGTGGACTCAGTGTCCCACACACCTACAC
CCTCCACGCCGGCTGGCTTCCGGGCCGTGTCCCCTGCTGTGCCCTTCTCTCGCTCCCGCCAGCCCTCACCATTGCTGCTGTTGCCACCCC
CTGCCGGCCTGACCTCGGATCCAGGGCCCTCTGTGCGCAGGGTGCCTGCTGTGCAGCGGGACTCACCTGTTATTGTCCGCAACCCTGATG
TGCCACTGCCCTCCAAATTCCCTGGGGAGGTGGGCACTGCTGGTGAGGTGCGGGCTGGGGGACCTGGGCGGGGCTGCCGTGAAACCCCAG
TGCCCCCTGGGGTGGCCAGTGGGAAGCCTGGCCTGCCCCCACCTCTGCCAGCCCCCGTGCCCATCACCGTGCCTCCAGCTGCACCAACTG
CCGTGGCCCAGCCGATGCCCGCCTTTGGCCTGGCTTCTTCACCCTTTCAGCCTGTGGCCTTCCACCCCTCACCTGCTGCCCTGTTGCCCG
TTTTGGTGCCCAGCAGCTATACCAGCCACCCTGCCCCCAAGAAGGAAGTCATCATGGGCCGGCCTGGAACAGTGTGGACGAATGTGGAAC
CTCGCTCTGTGGCTGTGTTCCCTTGGCACTCCTTAGTCCCCTTCCTGGCACCCAGCCAGCCTGACCCCTCCGTGCAGCCGAGCGAGGCCC
AGCAACCTGCCAGCCACCCAGTGGCCTCCAACCAGAGCAAAGAACCTGCTGAGTCGGCAGCTGTTGCTCATGAACGGCCACCAGGTGGGA
CAGGGAGTGCTGACCCTGAGCGGCCCCCTGGAGCCACATGCCCTGAGAGCCCAGGACCCGGACCCCCACACCCTTTGGGGGTGGTGGAAT
CTGGTAAGGGTCCGCCTCCCACCACGGAGGAGGAGGCCTCCGGCCCCCCAGGAGAGCCCCGGCTGGACAGTGAGACAGAGAGTGACCATG
ATGATGCAAGGCAAGAAGAAAGAGCTTCGAGAACAACATCCCAGTCTGAGAGATGAGGGGACTAGTGATGACAAGGTCTTCCTTGCATGC
AGAGGGGCCGGCCAGTGCCCCCTATCTGCCCCAGCTGGGACTATGGACAGGACCCGGGTGCTTCAAGCATCCCAGGCTGGGCCACCCTTT
TTTTGCTACACCTGTGGCAAATGTTTCAGCAGGCGCTCCTACCTCTATAGCCACCAGTTTGTTCACAATCCCAAGCTGACTAACAGCTGC
AGTCAGTGTGGGAAGTTGTTTCGGAGCCCCAAGTCCCTCAGCTATCACAGACGCATGCATCTTGGGGAGAGGCCCTTCTGTTGCACGCTC
TGTGACAAGACCTACTGTGATGCTTCTGGACTAAGTCGTCACCGCCGCGTCCATCTGGGTTACCGGCCCCATTCATGCTCTGTGTGTGGG
AAGAGCTTCCGGGACCAGTCTGAGCTCAAACGCCACCAGAAGATACACCAAAACCAGGAGCCAGTGGATGGAAACCAGGAGTGTACTTTG
AGGATTCCAGGCACCCAGGCTGAATTCCAGACACCCATCGCCAGAAGCCAGAGGTCCATCCAGGGGCTTTTGGATGTGAACCATGCACCA
GTGGCCAGGTCCCAGGAACCCATATTTAGAACTGAGGGTCCTATGGCCCAGAACCAGGCATCTGTACTTAAGAACCAAGCACCTGTGACC
AGGACCCAGGCACCCATCACTGGAACCCTCTGTCAGGATGCCAGATCCAACTCTCATCCAGTGAAGCCCTCAAGACTCAATGTCTTCTGT
TGCCCCCATTGTTCTTTGACTTTTAGCAAGAAATCCTATCTCTCCAGACACCAGAAGGCCCACCTCACAGAGCCGCCCAACTACTGCTTC
CATTGCAGCAAGTCTTTCAGCTCATTTTCCAGGCTGGTCAGACACCAGCAGACCCACTGGAAGCAGAAGAGCTACCTTTGCCCTATCTGT
GACCTCTCCTTTGGGGAGAAAGAGGGCCTTATGGATCACTGGAGGGGCTATAAAGGCAAGGACCTGTGCCAGAGCAGCCACCATAAATGC
CGGGTGATCCTGGGCCAGTGGCTTGGCTTCTCTCATGATGTCCCCACTATGGCTGGGGAGGAATGGAAGCATGGAGGTGATCAATCTCCC
CCCAGGATCCATACCCCCAGGAGAAGAGGCCTAAGAGAGAAGGCCTGCAAAGGAGACAAAACAAAGGAGGCAGTGAGCATCTTGAAACAT
AAATAAATGGCCTTTCTGACTGA

>16804_16804_4_CIC-ZFP57_CIC_chr19_42791392_ENST00000572681_ZFP57_chr6_29641535_ENST00000376883_length(amino acids)=1075AA_BP=1060
MKPMKKACTGLSGPGSGSKSPPATRAKALRRRGAGEGDKPEEEDDEAQQPQPQSGPEEAEEGEEEEAERGPGAEGPPLELHPGDPAPGPA
EDPKGDGEAGRWEPSLSRKTATFKSRAPKKKYVEEHGAGSSGVAGAPEERVRTPEEASGLGVPPRPPTSTRSSSTDTASEHSADLEDEPA
EACGPGPWPPGSTSGSYDLRQLRSQRVLARRGDGLFLPAVVRQVRRSQDLGVQFPGDRALTFYEGVPGAGVDVVLDATPPPGALVVGTAV
CTCVEPGVAAYREGVVVEVATKPAAYKVRLSPGPSSQPGLPGSLPQPPQPLHREPEEAVWVARSSLRLLRPPWEPETMLRKPPTGPEEEQ
AEPGATLPPCPAALDPKQPEDAEVSKISFGGNLGTHCEEGEEKHPPALGTPALLPLPPPQLLSPPPKSPAFVGPGRPGEQPSPCQEGSQG
GSRSSSVASLEKGTAPAARARTPLTAAQQKYKKGDVVCTPSGIRKKFNGKQWRRLCSRDGCMKESQRRGYCSRHLSMRTKEMEGLADSGP
GGAGRPAAVAAREGSTEFDWGDETSRDSEASSVAARGDSRPRLVAPADLSRFEFDECEAAVMLVSLGSSRSGTPSFSPVSTQSPFSPAPS
PSPSPLFGFRPANFSPINASPVIQRTAVRSRHLSASTPKAGVLTPPDLGPHPPPPAPRERHSSGILPTFQTNLTFTVPISPGRRKTELLP
HPGALGAPGAGGGGAAPDFPKSDSLDSGVDSVSHTPTPSTPAGFRAVSPAVPFSRSRQPSPLLLLPPPAGLTSDPGPSVRRVPAVQRDSP
VIVRNPDVPLPSKFPGEVGTAGEVRAGGPGRGCRETPVPPGVASGKPGLPPPLPAPVPITVPPAAPTAVAQPMPAFGLASSPFQPVAFHP
SPAALLPVLVPSSYTSHPAPKKEVIMGRPGTVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVA
HERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDARQEERASRTTSQSER

--------------------------------------------------------------
>16804_16804_5_CIC-ZFP57_CIC_chr19_42791392_ENST00000575354_ZFP57_chr6_29641535_ENST00000376881_length(transcript)=1859nt_BP=492nt
GGAGGTGCGAGCCCCTGCCGGGTCCCCCCTGCGCCGGACCATGTATTCGGCCCACAGGCCCCTGATGCCCGCGTCCAGCGCGGCCTCCCG
TGGCCTCGGCATGTTCGTGTGGACGAATGTGGAACCTCGCTCTGTGGCTGTGTTCCCTTGGCACTCCTTAGTCCCCTTCCTGGCACCCAG
CCAGCCTGACCCCTCCGTGCAGCCGAGCGAGGCCCAGCAACCTGCCAGCCACCCAGTGGCCTCCAACCAGAGCAAAGAACCTGCTGAGTC
GGCAGCTGTTGCTCATGAACGGCCACCAGGTGGGACAGGGAGTGCTGACCCTGAGCGGCCCCCTGGAGCCACATGCCCTGAGAGCCCAGG
ACCCGGACCCCCACACCCTTTGGGGGTGGTGGAATCTGGTAAGGGTCCGCCTCCCACCACGGAGGAGGAGGCCTCCGGCCCCCCAGGAGA
GCCCCGGCTGGACAGTGAGACAGAGAGTGACCATGATGATGCAAGGCAAGAAGAAAGAGCTTCGAGAACAACATCCCAGTCTGAGAGATG
AGGGGACTAGTGATGACAAGGTCTTCCTTGCATGCAGAGGGGCCGGCCAGTGCCCCCTATCTGCCCCAGCTGGGACTATGGACAGGACCC
GGGTGCTTCAAGCATCCCAGGCTGGGCCACCCTTTTTTTGCTACACCTGTGGCAAATGTTTCAGCAGGCGCTCCTACCTCTATAGCCACC
AGTTTGTTCACAATCCCAAGCTGACTAACAGCTGCAGTCAGTGTGGGAAGTTGTTTCGGAGCCCCAAGTCCCTCAGCTATCACAGACGCA
TGCATCTTGGGGAGAGGCCCTTCTGTTGCACGCTCTGTGACAAGACCTACTGTGATGCTTCTGGACTAAGTCGTCACCGCCGCGTCCATC
TGGGTTACCGGCCCCATTCATGCTCTGTGTGTGGGAAGAGCTTCCGGGACCAGTCTGAGCTCAAACGCCACCAGAAGATACACCAAAACC
AGGAGCCAGTGGATGGAAACCAGGAGTGTACTTTGAGGATTCCAGGCACCCAGGCTGAATTCCAGACACCCATCGCCAGAAGCCAGAGGT
CCATCCAGGGGCTTTTGGATGTGAACCATGCACCAGTGGCCAGGTCCCAGGAACCCATATTTAGAACTGAGGGTCCTATGGCCCAGAACC
AGGCATCTGTACTTAAGAACCAAGCACCTGTGACCAGGACCCAGGCACCCATCACTGGAACCCTCTGTCAGGATGCCAGATCCAACTCTC
ATCCAGTGAAGCCCTCAAGACTCAATGTCTTCTGTTGCCCCCATTGTTCTTTGACTTTTAGCAAGAAATCCTATCTCTCCAGACACCAGA
AGGCCCACCTCACAGAGCCGCCCAACTACTGCTTCCATTGCAGCAAGTCTTTCAGCTCATTTTCCAGGCTGGTCAGACACCAGCAGACCC
ACTGGAAGCAGAAGAGCTACCTTTGCCCTATCTGTGACCTCTCCTTTGGGGAGAAAGAGGGCCTTATGGATCACTGGAGGGGCTATAAAG
GCAAGGACCTGTGCCAGAGCAGCCACCATAAATGCCGGGTGATCCTGGGCCAGTGGCTTGGCTTCTCTCATGATGTCCCCACTATGGCTG
GGGAGGAATGGAAGCATGGAGGTGATCAATCTCCCCCCAGGATCCATACCCCCAGGAGAAGAGGCCTAAGAGAGAAGGCCTGCAAAGGAG
ACAAAACAAAGGAGGCAGTGAGCATCTTGAAACATAAATAAATGGCCTTTCTGACTGAGCTCTTTCTTTGTGTTTAGTTTTCCTGAGGAC
TGACCTCTGGGGTAATGAGGCTGGAGTAGAGGGAGACAGGTGCGTGGATAAGGAAGGAA

>16804_16804_5_CIC-ZFP57_CIC_chr19_42791392_ENST00000575354_ZFP57_chr6_29641535_ENST00000376881_length(amino acids)=521AA_BP=103
MTPPCSRARPSNLPATQWPPTRAKNLLSRQLLLMNGHQVGQGVLTLSGPLEPHALRAQDPDPHTLWGWWNLVRVRLPPRRRRPPAPQESP
GWTVRQRVTMMMQGKKKELREQHPSLRDEGTSDDKVFLACRGAGQCPLSAPAGTMDRTRVLQASQAGPPFFCYTCGKCFSRRSYLYSHQF
VHNPKLTNSCSQCGKLFRSPKSLSYHRRMHLGERPFCCTLCDKTYCDASGLSRHRRVHLGYRPHSCSVCGKSFRDQSELKRHQKIHQNQE
PVDGNQECTLRIPGTQAEFQTPIARSQRSIQGLLDVNHAPVARSQEPIFRTEGPMAQNQASVLKNQAPVTRTQAPITGTLCQDARSNSHP
VKPSRLNVFCCPHCSLTFSKKSYLSRHQKAHLTEPPNYCFHCSKSFSSFSRLVRHQQTHWKQKSYLCPICDLSFGEKEGLMDHWRGYKGK
DLCQSSHHKCRVILGQWLGFSHDVPTMAGEEWKHGGDQSPPRIHTPRRRGLREKACKGDKTKEAVSILKHK

--------------------------------------------------------------
>16804_16804_6_CIC-ZFP57_CIC_chr19_42791392_ENST00000575354_ZFP57_chr6_29641535_ENST00000376883_length(transcript)=1768nt_BP=492nt
GGAGGTGCGAGCCCCTGCCGGGTCCCCCCTGCGCCGGACCATGTATTCGGCCCACAGGCCCCTGATGCCCGCGTCCAGCGCGGCCTCCCG
TGGCCTCGGCATGTTCGTGTGGACGAATGTGGAACCTCGCTCTGTGGCTGTGTTCCCTTGGCACTCCTTAGTCCCCTTCCTGGCACCCAG
CCAGCCTGACCCCTCCGTGCAGCCGAGCGAGGCCCAGCAACCTGCCAGCCACCCAGTGGCCTCCAACCAGAGCAAAGAACCTGCTGAGTC
GGCAGCTGTTGCTCATGAACGGCCACCAGGTGGGACAGGGAGTGCTGACCCTGAGCGGCCCCCTGGAGCCACATGCCCTGAGAGCCCAGG
ACCCGGACCCCCACACCCTTTGGGGGTGGTGGAATCTGGTAAGGGTCCGCCTCCCACCACGGAGGAGGAGGCCTCCGGCCCCCCAGGAGA
GCCCCGGCTGGACAGTGAGACAGAGAGTGACCATGATGATGCAAGGCAAGAAGAAAGAGCTTCGAGAACAACATCCCAGTCTGAGAGATG
AGGGGACTAGTGATGACAAGGTCTTCCTTGCATGCAGAGGGGCCGGCCAGTGCCCCCTATCTGCCCCAGCTGGGACTATGGACAGGACCC
GGGTGCTTCAAGCATCCCAGGCTGGGCCACCCTTTTTTTGCTACACCTGTGGCAAATGTTTCAGCAGGCGCTCCTACCTCTATAGCCACC
AGTTTGTTCACAATCCCAAGCTGACTAACAGCTGCAGTCAGTGTGGGAAGTTGTTTCGGAGCCCCAAGTCCCTCAGCTATCACAGACGCA
TGCATCTTGGGGAGAGGCCCTTCTGTTGCACGCTCTGTGACAAGACCTACTGTGATGCTTCTGGACTAAGTCGTCACCGCCGCGTCCATC
TGGGTTACCGGCCCCATTCATGCTCTGTGTGTGGGAAGAGCTTCCGGGACCAGTCTGAGCTCAAACGCCACCAGAAGATACACCAAAACC
AGGAGCCAGTGGATGGAAACCAGGAGTGTACTTTGAGGATTCCAGGCACCCAGGCTGAATTCCAGACACCCATCGCCAGAAGCCAGAGGT
CCATCCAGGGGCTTTTGGATGTGAACCATGCACCAGTGGCCAGGTCCCAGGAACCCATATTTAGAACTGAGGGTCCTATGGCCCAGAACC
AGGCATCTGTACTTAAGAACCAAGCACCTGTGACCAGGACCCAGGCACCCATCACTGGAACCCTCTGTCAGGATGCCAGATCCAACTCTC
ATCCAGTGAAGCCCTCAAGACTCAATGTCTTCTGTTGCCCCCATTGTTCTTTGACTTTTAGCAAGAAATCCTATCTCTCCAGACACCAGA
AGGCCCACCTCACAGAGCCGCCCAACTACTGCTTCCATTGCAGCAAGTCTTTCAGCTCATTTTCCAGGCTGGTCAGACACCAGCAGACCC
ACTGGAAGCAGAAGAGCTACCTTTGCCCTATCTGTGACCTCTCCTTTGGGGAGAAAGAGGGCCTTATGGATCACTGGAGGGGCTATAAAG
GCAAGGACCTGTGCCAGAGCAGCCACCATAAATGCCGGGTGATCCTGGGCCAGTGGCTTGGCTTCTCTCATGATGTCCCCACTATGGCTG
GGGAGGAATGGAAGCATGGAGGTGATCAATCTCCCCCCAGGATCCATACCCCCAGGAGAAGAGGCCTAAGAGAGAAGGCCTGCAAAGGAG
ACAAAACAAAGGAGGCAGTGAGCATCTTGAAACATAAATAAATGGCCTTTCTGACTGA

>16804_16804_6_CIC-ZFP57_CIC_chr19_42791392_ENST00000575354_ZFP57_chr6_29641535_ENST00000376883_length(amino acids)=521AA_BP=103
MTPPCSRARPSNLPATQWPPTRAKNLLSRQLLLMNGHQVGQGVLTLSGPLEPHALRAQDPDPHTLWGWWNLVRVRLPPRRRRPPAPQESP
GWTVRQRVTMMMQGKKKELREQHPSLRDEGTSDDKVFLACRGAGQCPLSAPAGTMDRTRVLQASQAGPPFFCYTCGKCFSRRSYLYSHQF
VHNPKLTNSCSQCGKLFRSPKSLSYHRRMHLGERPFCCTLCDKTYCDASGLSRHRRVHLGYRPHSCSVCGKSFRDQSELKRHQKIHQNQE
PVDGNQECTLRIPGTQAEFQTPIARSQRSIQGLLDVNHAPVARSQEPIFRTEGPMAQNQASVLKNQAPVTRTQAPITGTLCQDARSNSHP
VKPSRLNVFCCPHCSLTFSKKSYLSRHQKAHLTEPPNYCFHCSKSFSSFSRLVRHQQTHWKQKSYLCPICDLSFGEKEGLMDHWRGYKGK
DLCQSSHHKCRVILGQWLGFSHDVPTMAGEEWKHGGDQSPPRIHTPRRRGLREKACKGDKTKEAVSILKHK

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for CIC-ZFP57


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneCICchr19:42791392chr6:29641535ENST00000575354+32028_46150.666666666666661609.0ATXN1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for CIC-ZFP57


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for CIC-ZFP57


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCICC4539848MENTAL RETARDATION, AUTOSOMAL DOMINANT 453GENOMICS_ENGLAND;UNIPROT
HgeneCICC0020796Profound Mental Retardation2CTD_human
HgeneCICC0025363Mental Retardation, Psychosocial2CTD_human
HgeneCICC0917816Mental deficiency2CTD_human
HgeneCICC3714756Intellectual Disability2CTD_human
HgeneCICC0027627Neoplasm Metastasis1CTD_human
HgeneCICC0041671Attention Deficit Disorder1CTD_human
HgeneCICC0087012Ataxia, Spinocerebellar1CTD_human
HgeneCICC0752120Spinocerebellar Ataxia Type 11CTD_human
HgeneCICC0752121Spinocerebellar Ataxia Type 21CTD_human
HgeneCICC0752122Spinocerebellar Ataxia Type 41CTD_human
HgeneCICC0752123Spinocerebellar Ataxia Type 51CTD_human
HgeneCICC0752124Spinocerebellar Ataxia Type 6 (disorder)1CTD_human
HgeneCICC0752125Spinocerebellar Ataxia Type 71CTD_human
HgeneCICC1263846Attention deficit hyperactivity disorder1CTD_human
HgeneCICC1321905Minimal Brain Dysfunction1CTD_human
HgeneCICC1510586Autism Spectrum Disorders1CTD_human
TgeneC1832386Diabetes Mellitus, Transient Neonatal, 14CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC0011849Diabetes Mellitus1CTD_human