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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ATP11B-NET1 (FusionGDB2 ID:HG23200TG10276)

Fusion Gene Summary for ATP11B-NET1

check button Fusion gene summary
Fusion gene informationFusion gene name: ATP11B-NET1
Fusion gene ID: hg23200tg10276
HgeneTgene
Gene symbol

ATP11B

NET1

Gene ID

23200

10276

Gene nameATPase phospholipid transporting 11B (putative)neuroepithelial cell transforming 1
SynonymsATPIF|ATPIRARHGEF8|NET1A
Cytomap('ATP11B')('NET1')

3q26.33

10p15.1

Type of geneprotein-codingprotein-coding
Descriptionprobable phospholipid-transporting ATPase IFATPase IRATPase, class VI, type 11BP4-ATPase flippase complex alpha subunit ATP11Btruncated ATPase 11B proteinneuroepithelial cell-transforming gene 1 proteinRho guanine nucleotide exchange factor (GEF) 8epididymis secretory sperm binding proteinguanine nucleotide regulatory protein (oncogene)neuroepithelioma transforming gene 1p65 Net1 proto-oncogene protei
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000323116, ENST00000482794, 
ENST00000493826, 
Fusion gene scores* DoF score20 X 15 X 10=30005 X 6 X 6=180
# samples 229
** MAII scorelog2(22/3000*10)=-3.76938707185858
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/180*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ATP11B [Title/Abstract] AND NET1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointATP11B(182616560)-NET1(5493793), # samples:3
Anticipated loss of major functional domain due to fusion event.ATP11B-NET1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ATP11B-NET1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ATP11B-NET1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ATP11B-NET1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneNET1

GO:0043065

positive regulation of apoptotic process

21373644

TgeneNET1

GO:0070301

cellular response to hydrogen peroxide

21373644

TgeneNET1

GO:0071479

cellular response to ionizing radiation

21373644


check buttonFusion gene breakpoints across ATP11B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across NET1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-XF-AAN4-01AATP11Bchr3

182616560

-NET1chr10

5493793

+
ChimerDB4BLCATCGA-XF-AAN4-01AATP11Bchr3

182616560

+NET1chr10

5493793

+
ChimerDB4BLCATCGA-XF-AAN4ATP11Bchr3

182616560

+NET1chr10

5493792

+
ChimerDB4BLCATCGA-XF-AAN4ATP11Bchr3

182616560

+NET1chr10

5493793

+


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Fusion Gene ORF analysis for ATP11B-NET1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000323116ENST00000380359ATP11Bchr3

182616560

+NET1chr10

5493793

+
5CDS-5UTRENST00000323116ENST00000380359ATP11Bchr3

182616560

+NET1chr10

5493792

+
5CDS-5UTRENST00000323116ENST00000542715ATP11Bchr3

182616560

+NET1chr10

5493793

+
5CDS-5UTRENST00000323116ENST00000542715ATP11Bchr3

182616560

+NET1chr10

5493792

+
5CDS-intronENST00000323116ENST00000484741ATP11Bchr3

182616560

+NET1chr10

5493793

+
5CDS-intronENST00000323116ENST00000484741ATP11Bchr3

182616560

+NET1chr10

5493792

+
In-frameENST00000323116ENST00000355029ATP11Bchr3

182616560

+NET1chr10

5493793

+
In-frameENST00000323116ENST00000355029ATP11Bchr3

182616560

+NET1chr10

5493792

+
intron-3CDSENST00000482794ENST00000355029ATP11Bchr3

182616560

+NET1chr10

5493793

+
intron-3CDSENST00000482794ENST00000355029ATP11Bchr3

182616560

+NET1chr10

5493792

+
intron-3CDSENST00000493826ENST00000355029ATP11Bchr3

182616560

+NET1chr10

5493793

+
intron-3CDSENST00000493826ENST00000355029ATP11Bchr3

182616560

+NET1chr10

5493792

+
intron-5UTRENST00000482794ENST00000380359ATP11Bchr3

182616560

+NET1chr10

5493793

+
intron-5UTRENST00000482794ENST00000380359ATP11Bchr3

182616560

+NET1chr10

5493792

+
intron-5UTRENST00000482794ENST00000542715ATP11Bchr3

182616560

+NET1chr10

5493793

+
intron-5UTRENST00000482794ENST00000542715ATP11Bchr3

182616560

+NET1chr10

5493792

+
intron-5UTRENST00000493826ENST00000380359ATP11Bchr3

182616560

+NET1chr10

5493793

+
intron-5UTRENST00000493826ENST00000380359ATP11Bchr3

182616560

+NET1chr10

5493792

+
intron-5UTRENST00000493826ENST00000542715ATP11Bchr3

182616560

+NET1chr10

5493793

+
intron-5UTRENST00000493826ENST00000542715ATP11Bchr3

182616560

+NET1chr10

5493792

+
intron-intronENST00000482794ENST00000484741ATP11Bchr3

182616560

+NET1chr10

5493793

+
intron-intronENST00000482794ENST00000484741ATP11Bchr3

182616560

+NET1chr10

5493792

+
intron-intronENST00000493826ENST00000484741ATP11Bchr3

182616560

+NET1chr10

5493793

+
intron-intronENST00000493826ENST00000484741ATP11Bchr3

182616560

+NET1chr10

5493792

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000323116ATP11Bchr3182616560+ENST00000355029NET1chr105493793+6583357820651131635
ENST00000323116ATP11Bchr3182616560+ENST00000355029NET1chr105493792+6583357820651131635

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000323116ENST00000355029ATP11Bchr3182616560+NET1chr105493793+0.0002241820.9997758
ENST00000323116ENST00000355029ATP11Bchr3182616560+NET1chr105493792+0.0002241820.9997758

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Fusion Genomic Features for ATP11B-NET1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ATP11Bchr3182616560+NET1chr105493792+4.35E-050.9999565
ATP11Bchr3182616560+NET1chr105493792+4.35E-050.9999565
ATP11Bchr3182616560+NET1chr105493792+4.35E-050.9999565
ATP11Bchr3182616560+NET1chr105493792+4.35E-050.9999565

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ATP11B-NET1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:182616560/chr10:5493793)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+28301021_102511061178.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+28301048_106511061178.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+2830105_28911061178.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+28301_5511061178.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+2830312_34111061178.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+2830360_87611061178.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+283078_8211061178.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+2830899_91011061178.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+2830931_96011061178.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+2830983_99711061178.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+28301021_102511061178.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+28301048_106511061178.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+2830105_28911061178.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+28301_5511061178.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+2830312_34111061178.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+2830360_87611061178.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+283078_8211061178.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+2830899_91011061178.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+2830931_96011061178.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+2830983_99711061178.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+28301026_104711061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+28301066_109011061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+2830290_31111061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+2830342_35911061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+283056_7711061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+283083_10411061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+2830877_89811061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+2830911_93011061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+2830961_98211061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+2830998_102011061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+28301026_104711061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+28301066_109011061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+2830290_31111061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+2830342_35911061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+283056_7711061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+283083_10411061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+2830877_89811061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+2830911_93011061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+2830961_98211061178.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+2830998_102011061178.0TransmembraneHelical
TgeneNET1chr3:182616560chr10:5493792ENST00000355029212174_35685597.0DomainDH
TgeneNET1chr3:182616560chr10:5493792ENST00000355029212386_50185597.0DomainPH
TgeneNET1chr3:182616560chr10:5493792ENST00000380359010174_35631543.0DomainDH
TgeneNET1chr3:182616560chr10:5493792ENST00000380359010386_50131543.0DomainPH
TgeneNET1chr3:182616560chr10:5493793ENST00000355029212174_35685597.0DomainDH
TgeneNET1chr3:182616560chr10:5493793ENST00000355029212386_50185597.0DomainPH
TgeneNET1chr3:182616560chr10:5493793ENST00000380359010174_35631543.0DomainDH
TgeneNET1chr3:182616560chr10:5493793ENST00000380359010386_50131543.0DomainPH
TgeneNET1chr3:182616560chr10:5493792ENST0000038035901066_7231543.0MotifNuclear localization signal
TgeneNET1chr3:182616560chr10:5493793ENST0000038035901066_7231543.0MotifNuclear localization signal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP11Bchr3:182616560chr10:5493792ENST00000323116+28301091_117711061178.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+161021_10250196.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+161048_10650196.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+16105_2890196.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+161091_11770196.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+161_550196.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+16312_3410196.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+16360_8760196.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+1678_820196.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+16899_9100196.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+16931_9600196.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+16983_9970196.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493793ENST00000323116+28301091_117711061178.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+161021_10250196.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+161048_10650196.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+16105_2890196.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+161091_11770196.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+161_550196.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+16312_3410196.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+16360_8760196.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+1678_820196.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+16899_9100196.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+16931_9600196.0Topological domainCytoplasmic
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+16983_9970196.0Topological domainExtracellular
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+161026_10470196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+161066_10900196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+16290_3110196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+16342_3590196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+1656_770196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+1683_1040196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+16877_8980196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+16911_9300196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+16961_9820196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493792ENST00000493826+16998_10200196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+161026_10470196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+161066_10900196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+16290_3110196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+16342_3590196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+1656_770196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+1683_1040196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+16877_8980196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+16911_9300196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+16961_9820196.0TransmembraneHelical
HgeneATP11Bchr3:182616560chr10:5493793ENST00000493826+16998_10200196.0TransmembraneHelical
TgeneNET1chr3:182616560chr10:5493792ENST0000035502921212_1985597.0MotifNuclear localization signal
TgeneNET1chr3:182616560chr10:5493792ENST0000035502921266_7285597.0MotifNuclear localization signal
TgeneNET1chr3:182616560chr10:5493792ENST0000038035901012_1931543.0MotifNuclear localization signal
TgeneNET1chr3:182616560chr10:5493793ENST0000035502921212_1985597.0MotifNuclear localization signal
TgeneNET1chr3:182616560chr10:5493793ENST0000035502921266_7285597.0MotifNuclear localization signal
TgeneNET1chr3:182616560chr10:5493793ENST0000038035901012_1931543.0MotifNuclear localization signal
TgeneNET1chr3:182616560chr10:5493792ENST000003550292121_7485597.0RegionNecessary for nuclear localization
TgeneNET1chr3:182616560chr10:5493792ENST000003803590101_7431543.0RegionNecessary for nuclear localization
TgeneNET1chr3:182616560chr10:5493793ENST000003550292121_7485597.0RegionNecessary for nuclear localization
TgeneNET1chr3:182616560chr10:5493793ENST000003803590101_7431543.0RegionNecessary for nuclear localization


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Fusion Gene Sequence for ATP11B-NET1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>7737_7737_1_ATP11B-NET1_ATP11B_chr3_182616560_ENST00000323116_NET1_chr10_5493792_ENST00000355029_length(transcript)=6583nt_BP=3578nt
GGTCAATAATGAAGGTGGCTGCGGCGCGGCGGCAGGCTCAGCTGCGCCGGGCGGGGGCGGCGCCGGGGCCGCGCCTGTAGGACTCGGGGC
CGACGCCGCGGGATGGGGACGCGGCGCGGGGAGTGAGGCAGTGGCGGCGGCGGCGGTAAGCGGAACTTCGGCCCGAGGGGCTCGCCCGCT
CCCGCCTCTGTCTTGTCGGCCTCCACCTGCAGCCCCGCGGCCCCCGCGCCCCGCGGGACCCGGACGGCGACGACGGGGGAATGTGGCGCT
GGATCCGGCAGCAGCTGGGTTTTGACCCACCACATCAGAGTGACACAAGAACCATCTACGTAGCCAACAGGTTTCCTCAGAATGGCCTTT
ACACACCTCAGAAATTTATAGATAACAGGATCATTTCATCTAAGTACACTGTGTGGAATTTTGTTCCAAAAAATTTATTTGAACAGTTCA
GAAGAGTGGCAAACTTTTATTTTCTTATTATATTTTTGGTTCAGCTTATGATTGATACACCTACCAGTCCAGTTACCAGTGGACTTCCAT
TATTCTTTGTGATAACAGTAACTGCCATAAAGCAGGGATATGAAGATTGGTTACGGCATAACTCAGATAATGAAGTAAATGGAGCTCCTG
TTTATGTTGTTCGAAGTGGTGGCCTTGTAAAAACTAGATCAAAAAACATTCGGGTGGGTGATATTGTTCGAATAGCCAAAGATGAAATTT
TTCCTGCAGACTTGGTGCTTCTGTCCTCAGATCGACTGGATGGTTCCTGTCACGTTACAACTGCTAGTTTGGACGGAGAAACTAACCTGA
AGACACATGTGGCAGTTCCAGAAACAGCATTATTACAAACAGTTGCCAATTTGGACACTCTAGTAGCTGTAATAGAATGCCAGCAACCAG
AAGCAGACTTATACAGATTCATGGGACGAATGATCATAACCCAACAAATGGAAGAAATTGTAAGACCTCTGGGGCCGGAGAGTCTCCTGC
TTCGTGGAGCCAGATTAAAAAACACAAAAGAAATTTTTGGTGTTGCGGTATACACTGGAATGGAAACTAAGATGGCATTAAATTACAAGA
GCAAATCACAGAAACGATCTGCAGTAGAAAAGTCAATGAATACATTTTTGATAATTTATCTAGTAATTCTTATATCTGAAGCTGTCATCA
GCACTATCTTGAAGTATACATGGCAAGCTGAAGAAAAATGGGATGAACCTTGGTATAACCAAAAAACAGAACATCAAAGAAATAGCAGTA
AGATTCTGAGATTTATTTCAGACTTCCTTGCTTTTTTGGTTCTCTACAATTTCATCATTCCAATTTCATTATATGTGACAGTCGAAATGC
AGAAATTTCTTGGATCATTTTTTATTGGCTGGGATCTTGATCTGTATCATGAAGAATCAGATCAGAAAGCTCAAGTCAATACTTCCGATC
TGAATGAAGAGCTTGGACAGGTAGAGTACGTGTTTACAGATAAAACTGGTACACTGACAGAAAATGAGATGCAGTTTCGGGAATGTTCAA
TTAATGGCATGAAATACCAAGAAATTAATGGTAGACTTGTACCCGAAGGACCAACACCAGACTCTTCAGAAGGAAACTTATCTTATCTTA
GTAGTTTATCCCATCTTAACAACTTATCCCATCTTACAACCAGTTCCTCTTTCAGAACCAGTCCTGAAAATGAAACTGAACTAATTAAAG
AACATGATCTCTTCTTTAAAGCAGTCAGTCTCTGTCACACTGTACAGATTAGCAATGTTCAAACTGACTGCACTGGTGATGGTCCCTGGC
AATCCAACCTGGCACCATCGCAGTTGGAGTACTATGCATCTTCACCAGATGAAAAGGCTCTAGTAGAAGCTGCTGCAAGGATTGGTATTG
TGTTTATTGGCAATTCTGAAGAAACTATGGAGGTTAAAACTCTTGGAAAACTGGAACGGTACAAACTGCTTCATATTCTGGAATTTGATT
CAGATCGTAGGAGAATGAGTGTAATTGTTCAGGCACCTTCAGGTGAGAAGTTATTATTTGCTAAAGGAGCTGAGTCATCAATTCTCCCTA
AATGTATAGGTGGAGAAATAGAAAAAACCAGAATTCATGTAGATGAATTTGCTTTGAAAGGGCTAAGAACTCTGTGTATAGCATATAGAA
AATTTACATCAAAAGAGTATGAGGAAATAGATAAACGCATATTTGAAGCCAGGACTGCCTTGCAGCAGCGGGAAGAGAAATTGGCAGCTG
TTTTCCAGTTCATAGAGAAAGACCTGATATTACTTGGAGCCACAGCAGTAGAAGACAGACTACAAGATAAAGTTCGAGAAACTATTGAAG
CATTGAGAATGGCTGGTATCAAAGTATGGGTACTTACTGGGGATAAACATGAAACAGCTGTTAGTGTGAGTTTATCATGTGGCCATTTTC
ATAGAACCATGAACATCCTTGAACTTATAAACCAGAAATCAGACAGCGAGTGTGCTGAACAATTGAGGCAGCTTGCCAGAAGAATTACAG
AGGATCATGTGATTCAGCATGGGCTGGTAGTGGATGGGACCAGCCTATCTCTTGCACTCAGGGAGCATGAAAAACTATTTATGGAAGTTT
GCAGAAATTGTTCAGCTGTATTATGCTGTCGTATGGCTCCACTGCAGAAAGCAAAAGTAATAAGACTAATAAAAATATCACCTGAGAAAC
CTATAACATTGGCTGTTGGTGATGGTGCTAATGACGTAAGCATGATACAAGAAGCCCATGTTGGCATAGGAATCATGGGTAAAGAAGGAA
GACAGGCTGCAAGAAACAGTGACTATGCAATAGCCAGATTTAAGTTCCTCTCCAAATTGCTTTTTGTTCATGGTCATTTTTATTATATTA
GAATAGCTACCCTTGTACAGTATTTTTTTTATAAGAATGTGTGCTTTATCACACCCCAGTTTTTATATCAGTTCTACTGTTTGTTTTCTC
AGCAAACATTGTATGACAGCGTGTACCTGACTTTATACAATATTTGTTTTACTTCCCTACCTATTCTGATATATAGTCTTTTGGAACAGC
ATGTAGACCCTCATGTGTTACAAAATAAGCCCACCCTTTATCGAGACATTAGTAAAAACCGCCTCTTAAGTATTAAAACATTTCTTTATT
GGACCATCCTGGGCTTCAGTCATGCCTTTATTTTCTTTTTTGGATCCTATTTACTAATAGGGAAAGATACATCTCTGCTTGGAAATGGCC
AGATGTTTGGAAACTGGACATTTGGCACTTTGGTCTTCACAGTCATGGTTATTACAGTCACAGTAAAGATGGCTCTGGAAACTCATTTTT
GGACTTGGATCAACCATCTCGTTACCTGGGGATCTATTATATTTTATTTTGTATTTTCCTTGTTTTATGGAGGGATTCTCTGGCCATTTT
TGGGCTCCCAGAATATGTATTTTGTGTTTATTCAGCTCCTGTCAAGTGGTTCTGCTTGGTTTGCCATAATCCTCATGGTTGTTACATGTC
TATTTCTTGATATCATAAAGAAGGTCTTTGACCGACACCTCCACCCTACAAGTACTGAAAAGGCACAGGAGCCAAGCAATAAAAGAGTTC
GACCTCTGGCTCGTGTCACGTCCTTGGCAAATTTAATCTCTCCTGTAAGAAATGGAGCTGTCAGACGTTTTGGTCAAACAATACAGTCAT
TTACCCTTCGTGGTGACCACAGATCCCCAGCCTCTGCCCAGAAGTTTTCTAGCAGGTCAACAGTCCCAACACCCGCCAAGAGAAGGAGCA
GTGCACTGTGGTCAGAGATGCTGGACATCACCATGAAGGAGTCTCTCACCACCAGGGAGATCAGACGGCAGGAGGCAATATATGAAATGT
CCCGAGGTGAACAGGATTTAATTGAGGATCTCAAACTTGCAAGAAAGGCCTATCATGACCCCATGTTAAAGTTGTCCATCATGTCAGAAG
AGGAACTCACACATATATTTGGTGATCTGGACTCTTACATACCTCTGCATGAAGATTTGTTGACAAGAATAGGAGAAGCAACCAAGCCTG
ATGGAACAGTGGAGCAGATTGGTCACATTCTCGTGAGCTGGTTACCGCGCTTGAATGCCTACAGAGGTTACTGTAGTAACCAGCTGGCAG
CCAAAGCTCTTCTTGATCAAAAGAAACAGGATCCAAGAGTCCAAGACTTCCTCCAGCGATGTCTCGAGTCTCCCTTCAGTCGAAAACTAG
ATCTTTGGAGTTTCCTAGATATCCCTCGAAGTCGCCTAGTCAAATACCCTTTACTGTTAAAAGAAATTCTTAAACACACTCCAAAAGAGC
ACCCTGATGTTCAGCTTCTGGAGGATGCTATATTGATAATACAGGGAGTCCTCTCTGATATCAACTTGAAGAAAGGTGAATCCGAGTGCC
AGTATTACATCGACAAGCTGGAGTACCTGGATGAAAAGCAGAGGGACCCCAGAATCGAAGCGAGCAAAGTGCTGCTGTGCCATGGGGAGC
TGCGGAGCAAGAGTGGACATAAACTTTACATTTTCCTGTTTCAAGACATCTTGGTTCTGACTCGGCCCGTCACACGGAACGAACGGCACT
CTTACCAGGTTTACCGGCAGCCAATCCCAGTCCAAGAGCTAGTCCTAGAAGACCTGCAGGATGGAGATGTGAGAATGGGAGGCTCCTTTC
GAGGAGCTTTCAGTAACTCAGAGAAAGCTAAAAATATCTTTAGAATTCGCTTCCATGACCCCTCTCCAGCCCAGTCTCACACTCTGCAAG
CCAATGACGTGTTCCACAAGCAGCAGTGGTTCAACTGTATTCGAGCGGCCATTGCCCCCTTCCAGTCGGCAGGCAGTCCACCTGAGCTGC
AGGGCCTGCCGGAGCTGCACGAAGAGTGTGAGGGGAACCACCCCTCTGCGAGGAAACTCACAGCCCAGAGGAGGGCATCCACAGTTTCCA
GTGTTACTCAGGTAGAAGTTGATGAAAACGCTTACAGATGTGGCTCTGGCATGCAGATGGCAGAGGACAGCAAGAGCTTAAAGACACACC
AGACACAGCCCGGCATCCGAAGAGCGAGGGACAAAGCCCTTTCTGGTGGCAAACGGAAAGAGACTTTGGTGTAGAGAAGGCTCTGTGTGT
TAACTGATGGGAGAGACTGTTTGTTTATAAATGTGTACAGTTTTGTTTTCTCGTAAGGGGAGCATCATAGGGTTACTTTATACCAGTTGT
AACATTTTCATTGTTTTTGGTTGTTCTTTTTTCTTTTTTTAATGGCAGCTAAAGATATACAGATTACTGTTAAATTGCAGTCCTTTTTTT
TTTAAAGATATTTTCTTGAATTATTTAGAACATGGTAAGCCTGGTATTTTTTAATCAAACAAAATATTTATGAAATGGGTTTTCTCTTAA
TTCTGGATTCATCATGGCTTTCTAATACCAATTGTAATATTTACAATATTCACCAAAACTTAGAATTTTGCAAATGCTGGAATTCTGCCA
GTGTTTCTTTGCTAAGCCTTGCATGCAAAATTTGAAATTTTAACATTGGCACCCAAAACCTACATGGAATGTATGTCTGGAGTATTTCAA
ACTTTACATTGAAACATAATTTCCTTGGAAAACAAACCATAAGCCTGAGGAGGTTTTTATCAACTGGAATGCTTTATATTAGTTTGTTTT
TCACTGTACATTCCTCATTTTACATTCATTTAACCTGCCGATTATTTAATTTTTTTATTGTAAAGTAGTTTTTAGCATTTGCTTTTATTT
TTTTACTTTGATGCCTTTTCAAATTGGCATGTCTTTAAAGTATTTTTCTTCCTGATTAAAAATGTGTGTGTATGTGTGTGTGTGTGTGTA
TATATATATATATTTTTAAATCACATTAATTTTACCAAGTGAAACCAAGCCATACTGTTTTTGAGCCAATTAAGAAAATTGCCATTTTTA
AAGTGTAGCATTTCAGGGTAAAGACCCATGAAATGGCTTGATGTATTCTAGACTACTGAAAGAAAACCACTTCAAAGATTTTGTTGAAAG
TTTTAGTGTTGTCTGAAATGCAAGAGGGAAGGTGATTGGTAGTGAGTTAAAAGAAAAAGAGAGGAAAAGAGAGTAGTTTTGTCTTCAAGT
AAAATGTCTGGTTGTGCCAGACATTTCACAAGTGTGAAAGGAGATAGGAGAAGCTCAACTTGAGGGCGTGTAGTAAGTTGTAGAAGGCTC
GAGGGGACGTGGACTTATTTGCCTTGGTTTGCAATACCTGCAAATAATGAGTTTGAAAAGAAACAATGAAATGTGTTAAAAATTTGACCA
TATTAGATAAATTTTCGTGGATTTAGTCATAAGATGGAAAAAGACTGGTGAATCTTTTATTACAAAATGTTTCTGTTAAAATGGGATCAT
CATCTTTGAAAGGGGGGAGGAGGAGTAAAAGCCCGATTATAATGGTGATCAATTCAAGTCAGTGTTGACTATTCTGTGAAATATATTTGG
CCAGTGGAAATGATAATCAGAAAAGACTGTAAATAGATCCATCCAAATGATTTCTCTGTACAAATGAATGATACTATTAAAAAAAAAAAA

>7737_7737_1_ATP11B-NET1_ATP11B_chr3_182616560_ENST00000323116_NET1_chr10_5493792_ENST00000355029_length(amino acids)=1635AA_BP=1124
MQPRGPRAPRDPDGDDGGMWRWIRQQLGFDPPHQSDTRTIYVANRFPQNGLYTPQKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFL
IIFLVQLMIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPADLVLLS
SDRLDGSCHVTTASLDGETNLKTHVAVPETALLQTVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNT
KEIFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKILRFISDF
LAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEI
NGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQL
EYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGEIEK
TRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKV
WVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSDSECAEQLRQLARRITEDHVIQHGLVVDGTSLSLALREHEKLFMEVCRNCSAVLC
CRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYF
FYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRLLSIKTFLYWTILGFSHA
FIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLGSQNMYFV
FIQLLSSGSAWFAIILMVVTCLFLDIIKKVFDRHLHPTSTEKAQEPSNKRVRPLARVTSLANLISPVRNGAVRRFGQTIQSFTLRGDHRS
PASAQKFSSRSTVPTPAKRRSSALWSEMLDITMKESLTTREIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGD
LDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRLNAYRGYCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIP
RSRLVKYPLLLKEILKHTPKEHPDVQLLEDAILIIQGVLSDINLKKGESECQYYIDKLEYLDEKQRDPRIEASKVLLCHGELRSKSGHKL
YIFLFQDILVLTRPVTRNERHSYQVYRQPIPVQELVLEDLQDGDVRMGGSFRGAFSNSEKAKNIFRIRFHDPSPAQSHTLQANDVFHKQQ
WFNCIRAAIAPFQSAGSPPELQGLPELHEECEGNHPSARKLTAQRRASTVSSVTQVEVDENAYRCGSGMQMAEDSKSLKTHQTQPGIRRA

--------------------------------------------------------------
>7737_7737_2_ATP11B-NET1_ATP11B_chr3_182616560_ENST00000323116_NET1_chr10_5493793_ENST00000355029_length(transcript)=6583nt_BP=3578nt
GGTCAATAATGAAGGTGGCTGCGGCGCGGCGGCAGGCTCAGCTGCGCCGGGCGGGGGCGGCGCCGGGGCCGCGCCTGTAGGACTCGGGGC
CGACGCCGCGGGATGGGGACGCGGCGCGGGGAGTGAGGCAGTGGCGGCGGCGGCGGTAAGCGGAACTTCGGCCCGAGGGGCTCGCCCGCT
CCCGCCTCTGTCTTGTCGGCCTCCACCTGCAGCCCCGCGGCCCCCGCGCCCCGCGGGACCCGGACGGCGACGACGGGGGAATGTGGCGCT
GGATCCGGCAGCAGCTGGGTTTTGACCCACCACATCAGAGTGACACAAGAACCATCTACGTAGCCAACAGGTTTCCTCAGAATGGCCTTT
ACACACCTCAGAAATTTATAGATAACAGGATCATTTCATCTAAGTACACTGTGTGGAATTTTGTTCCAAAAAATTTATTTGAACAGTTCA
GAAGAGTGGCAAACTTTTATTTTCTTATTATATTTTTGGTTCAGCTTATGATTGATACACCTACCAGTCCAGTTACCAGTGGACTTCCAT
TATTCTTTGTGATAACAGTAACTGCCATAAAGCAGGGATATGAAGATTGGTTACGGCATAACTCAGATAATGAAGTAAATGGAGCTCCTG
TTTATGTTGTTCGAAGTGGTGGCCTTGTAAAAACTAGATCAAAAAACATTCGGGTGGGTGATATTGTTCGAATAGCCAAAGATGAAATTT
TTCCTGCAGACTTGGTGCTTCTGTCCTCAGATCGACTGGATGGTTCCTGTCACGTTACAACTGCTAGTTTGGACGGAGAAACTAACCTGA
AGACACATGTGGCAGTTCCAGAAACAGCATTATTACAAACAGTTGCCAATTTGGACACTCTAGTAGCTGTAATAGAATGCCAGCAACCAG
AAGCAGACTTATACAGATTCATGGGACGAATGATCATAACCCAACAAATGGAAGAAATTGTAAGACCTCTGGGGCCGGAGAGTCTCCTGC
TTCGTGGAGCCAGATTAAAAAACACAAAAGAAATTTTTGGTGTTGCGGTATACACTGGAATGGAAACTAAGATGGCATTAAATTACAAGA
GCAAATCACAGAAACGATCTGCAGTAGAAAAGTCAATGAATACATTTTTGATAATTTATCTAGTAATTCTTATATCTGAAGCTGTCATCA
GCACTATCTTGAAGTATACATGGCAAGCTGAAGAAAAATGGGATGAACCTTGGTATAACCAAAAAACAGAACATCAAAGAAATAGCAGTA
AGATTCTGAGATTTATTTCAGACTTCCTTGCTTTTTTGGTTCTCTACAATTTCATCATTCCAATTTCATTATATGTGACAGTCGAAATGC
AGAAATTTCTTGGATCATTTTTTATTGGCTGGGATCTTGATCTGTATCATGAAGAATCAGATCAGAAAGCTCAAGTCAATACTTCCGATC
TGAATGAAGAGCTTGGACAGGTAGAGTACGTGTTTACAGATAAAACTGGTACACTGACAGAAAATGAGATGCAGTTTCGGGAATGTTCAA
TTAATGGCATGAAATACCAAGAAATTAATGGTAGACTTGTACCCGAAGGACCAACACCAGACTCTTCAGAAGGAAACTTATCTTATCTTA
GTAGTTTATCCCATCTTAACAACTTATCCCATCTTACAACCAGTTCCTCTTTCAGAACCAGTCCTGAAAATGAAACTGAACTAATTAAAG
AACATGATCTCTTCTTTAAAGCAGTCAGTCTCTGTCACACTGTACAGATTAGCAATGTTCAAACTGACTGCACTGGTGATGGTCCCTGGC
AATCCAACCTGGCACCATCGCAGTTGGAGTACTATGCATCTTCACCAGATGAAAAGGCTCTAGTAGAAGCTGCTGCAAGGATTGGTATTG
TGTTTATTGGCAATTCTGAAGAAACTATGGAGGTTAAAACTCTTGGAAAACTGGAACGGTACAAACTGCTTCATATTCTGGAATTTGATT
CAGATCGTAGGAGAATGAGTGTAATTGTTCAGGCACCTTCAGGTGAGAAGTTATTATTTGCTAAAGGAGCTGAGTCATCAATTCTCCCTA
AATGTATAGGTGGAGAAATAGAAAAAACCAGAATTCATGTAGATGAATTTGCTTTGAAAGGGCTAAGAACTCTGTGTATAGCATATAGAA
AATTTACATCAAAAGAGTATGAGGAAATAGATAAACGCATATTTGAAGCCAGGACTGCCTTGCAGCAGCGGGAAGAGAAATTGGCAGCTG
TTTTCCAGTTCATAGAGAAAGACCTGATATTACTTGGAGCCACAGCAGTAGAAGACAGACTACAAGATAAAGTTCGAGAAACTATTGAAG
CATTGAGAATGGCTGGTATCAAAGTATGGGTACTTACTGGGGATAAACATGAAACAGCTGTTAGTGTGAGTTTATCATGTGGCCATTTTC
ATAGAACCATGAACATCCTTGAACTTATAAACCAGAAATCAGACAGCGAGTGTGCTGAACAATTGAGGCAGCTTGCCAGAAGAATTACAG
AGGATCATGTGATTCAGCATGGGCTGGTAGTGGATGGGACCAGCCTATCTCTTGCACTCAGGGAGCATGAAAAACTATTTATGGAAGTTT
GCAGAAATTGTTCAGCTGTATTATGCTGTCGTATGGCTCCACTGCAGAAAGCAAAAGTAATAAGACTAATAAAAATATCACCTGAGAAAC
CTATAACATTGGCTGTTGGTGATGGTGCTAATGACGTAAGCATGATACAAGAAGCCCATGTTGGCATAGGAATCATGGGTAAAGAAGGAA
GACAGGCTGCAAGAAACAGTGACTATGCAATAGCCAGATTTAAGTTCCTCTCCAAATTGCTTTTTGTTCATGGTCATTTTTATTATATTA
GAATAGCTACCCTTGTACAGTATTTTTTTTATAAGAATGTGTGCTTTATCACACCCCAGTTTTTATATCAGTTCTACTGTTTGTTTTCTC
AGCAAACATTGTATGACAGCGTGTACCTGACTTTATACAATATTTGTTTTACTTCCCTACCTATTCTGATATATAGTCTTTTGGAACAGC
ATGTAGACCCTCATGTGTTACAAAATAAGCCCACCCTTTATCGAGACATTAGTAAAAACCGCCTCTTAAGTATTAAAACATTTCTTTATT
GGACCATCCTGGGCTTCAGTCATGCCTTTATTTTCTTTTTTGGATCCTATTTACTAATAGGGAAAGATACATCTCTGCTTGGAAATGGCC
AGATGTTTGGAAACTGGACATTTGGCACTTTGGTCTTCACAGTCATGGTTATTACAGTCACAGTAAAGATGGCTCTGGAAACTCATTTTT
GGACTTGGATCAACCATCTCGTTACCTGGGGATCTATTATATTTTATTTTGTATTTTCCTTGTTTTATGGAGGGATTCTCTGGCCATTTT
TGGGCTCCCAGAATATGTATTTTGTGTTTATTCAGCTCCTGTCAAGTGGTTCTGCTTGGTTTGCCATAATCCTCATGGTTGTTACATGTC
TATTTCTTGATATCATAAAGAAGGTCTTTGACCGACACCTCCACCCTACAAGTACTGAAAAGGCACAGGAGCCAAGCAATAAAAGAGTTC
GACCTCTGGCTCGTGTCACGTCCTTGGCAAATTTAATCTCTCCTGTAAGAAATGGAGCTGTCAGACGTTTTGGTCAAACAATACAGTCAT
TTACCCTTCGTGGTGACCACAGATCCCCAGCCTCTGCCCAGAAGTTTTCTAGCAGGTCAACAGTCCCAACACCCGCCAAGAGAAGGAGCA
GTGCACTGTGGTCAGAGATGCTGGACATCACCATGAAGGAGTCTCTCACCACCAGGGAGATCAGACGGCAGGAGGCAATATATGAAATGT
CCCGAGGTGAACAGGATTTAATTGAGGATCTCAAACTTGCAAGAAAGGCCTATCATGACCCCATGTTAAAGTTGTCCATCATGTCAGAAG
AGGAACTCACACATATATTTGGTGATCTGGACTCTTACATACCTCTGCATGAAGATTTGTTGACAAGAATAGGAGAAGCAACCAAGCCTG
ATGGAACAGTGGAGCAGATTGGTCACATTCTCGTGAGCTGGTTACCGCGCTTGAATGCCTACAGAGGTTACTGTAGTAACCAGCTGGCAG
CCAAAGCTCTTCTTGATCAAAAGAAACAGGATCCAAGAGTCCAAGACTTCCTCCAGCGATGTCTCGAGTCTCCCTTCAGTCGAAAACTAG
ATCTTTGGAGTTTCCTAGATATCCCTCGAAGTCGCCTAGTCAAATACCCTTTACTGTTAAAAGAAATTCTTAAACACACTCCAAAAGAGC
ACCCTGATGTTCAGCTTCTGGAGGATGCTATATTGATAATACAGGGAGTCCTCTCTGATATCAACTTGAAGAAAGGTGAATCCGAGTGCC
AGTATTACATCGACAAGCTGGAGTACCTGGATGAAAAGCAGAGGGACCCCAGAATCGAAGCGAGCAAAGTGCTGCTGTGCCATGGGGAGC
TGCGGAGCAAGAGTGGACATAAACTTTACATTTTCCTGTTTCAAGACATCTTGGTTCTGACTCGGCCCGTCACACGGAACGAACGGCACT
CTTACCAGGTTTACCGGCAGCCAATCCCAGTCCAAGAGCTAGTCCTAGAAGACCTGCAGGATGGAGATGTGAGAATGGGAGGCTCCTTTC
GAGGAGCTTTCAGTAACTCAGAGAAAGCTAAAAATATCTTTAGAATTCGCTTCCATGACCCCTCTCCAGCCCAGTCTCACACTCTGCAAG
CCAATGACGTGTTCCACAAGCAGCAGTGGTTCAACTGTATTCGAGCGGCCATTGCCCCCTTCCAGTCGGCAGGCAGTCCACCTGAGCTGC
AGGGCCTGCCGGAGCTGCACGAAGAGTGTGAGGGGAACCACCCCTCTGCGAGGAAACTCACAGCCCAGAGGAGGGCATCCACAGTTTCCA
GTGTTACTCAGGTAGAAGTTGATGAAAACGCTTACAGATGTGGCTCTGGCATGCAGATGGCAGAGGACAGCAAGAGCTTAAAGACACACC
AGACACAGCCCGGCATCCGAAGAGCGAGGGACAAAGCCCTTTCTGGTGGCAAACGGAAAGAGACTTTGGTGTAGAGAAGGCTCTGTGTGT
TAACTGATGGGAGAGACTGTTTGTTTATAAATGTGTACAGTTTTGTTTTCTCGTAAGGGGAGCATCATAGGGTTACTTTATACCAGTTGT
AACATTTTCATTGTTTTTGGTTGTTCTTTTTTCTTTTTTTAATGGCAGCTAAAGATATACAGATTACTGTTAAATTGCAGTCCTTTTTTT
TTTAAAGATATTTTCTTGAATTATTTAGAACATGGTAAGCCTGGTATTTTTTAATCAAACAAAATATTTATGAAATGGGTTTTCTCTTAA
TTCTGGATTCATCATGGCTTTCTAATACCAATTGTAATATTTACAATATTCACCAAAACTTAGAATTTTGCAAATGCTGGAATTCTGCCA
GTGTTTCTTTGCTAAGCCTTGCATGCAAAATTTGAAATTTTAACATTGGCACCCAAAACCTACATGGAATGTATGTCTGGAGTATTTCAA
ACTTTACATTGAAACATAATTTCCTTGGAAAACAAACCATAAGCCTGAGGAGGTTTTTATCAACTGGAATGCTTTATATTAGTTTGTTTT
TCACTGTACATTCCTCATTTTACATTCATTTAACCTGCCGATTATTTAATTTTTTTATTGTAAAGTAGTTTTTAGCATTTGCTTTTATTT
TTTTACTTTGATGCCTTTTCAAATTGGCATGTCTTTAAAGTATTTTTCTTCCTGATTAAAAATGTGTGTGTATGTGTGTGTGTGTGTGTA
TATATATATATATTTTTAAATCACATTAATTTTACCAAGTGAAACCAAGCCATACTGTTTTTGAGCCAATTAAGAAAATTGCCATTTTTA
AAGTGTAGCATTTCAGGGTAAAGACCCATGAAATGGCTTGATGTATTCTAGACTACTGAAAGAAAACCACTTCAAAGATTTTGTTGAAAG
TTTTAGTGTTGTCTGAAATGCAAGAGGGAAGGTGATTGGTAGTGAGTTAAAAGAAAAAGAGAGGAAAAGAGAGTAGTTTTGTCTTCAAGT
AAAATGTCTGGTTGTGCCAGACATTTCACAAGTGTGAAAGGAGATAGGAGAAGCTCAACTTGAGGGCGTGTAGTAAGTTGTAGAAGGCTC
GAGGGGACGTGGACTTATTTGCCTTGGTTTGCAATACCTGCAAATAATGAGTTTGAAAAGAAACAATGAAATGTGTTAAAAATTTGACCA
TATTAGATAAATTTTCGTGGATTTAGTCATAAGATGGAAAAAGACTGGTGAATCTTTTATTACAAAATGTTTCTGTTAAAATGGGATCAT
CATCTTTGAAAGGGGGGAGGAGGAGTAAAAGCCCGATTATAATGGTGATCAATTCAAGTCAGTGTTGACTATTCTGTGAAATATATTTGG
CCAGTGGAAATGATAATCAGAAAAGACTGTAAATAGATCCATCCAAATGATTTCTCTGTACAAATGAATGATACTATTAAAAAAAAAAAA

>7737_7737_2_ATP11B-NET1_ATP11B_chr3_182616560_ENST00000323116_NET1_chr10_5493793_ENST00000355029_length(amino acids)=1635AA_BP=1124
MQPRGPRAPRDPDGDDGGMWRWIRQQLGFDPPHQSDTRTIYVANRFPQNGLYTPQKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFL
IIFLVQLMIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPADLVLLS
SDRLDGSCHVTTASLDGETNLKTHVAVPETALLQTVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNT
KEIFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKILRFISDF
LAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEI
NGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQL
EYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGEIEK
TRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKV
WVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSDSECAEQLRQLARRITEDHVIQHGLVVDGTSLSLALREHEKLFMEVCRNCSAVLC
CRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYF
FYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRLLSIKTFLYWTILGFSHA
FIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLGSQNMYFV
FIQLLSSGSAWFAIILMVVTCLFLDIIKKVFDRHLHPTSTEKAQEPSNKRVRPLARVTSLANLISPVRNGAVRRFGQTIQSFTLRGDHRS
PASAQKFSSRSTVPTPAKRRSSALWSEMLDITMKESLTTREIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGD
LDSYIPLHEDLLTRIGEATKPDGTVEQIGHILVSWLPRLNAYRGYCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSRKLDLWSFLDIP
RSRLVKYPLLLKEILKHTPKEHPDVQLLEDAILIIQGVLSDINLKKGESECQYYIDKLEYLDEKQRDPRIEASKVLLCHGELRSKSGHKL
YIFLFQDILVLTRPVTRNERHSYQVYRQPIPVQELVLEDLQDGDVRMGGSFRGAFSNSEKAKNIFRIRFHDPSPAQSHTLQANDVFHKQQ
WFNCIRAAIAPFQSAGSPPELQGLPELHEECEGNHPSARKLTAQRRASTVSSVTQVEVDENAYRCGSGMQMAEDSKSLKTHQTQPGIRRA

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Fusion Gene PPI Analysis for ATP11B-NET1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ATP11B-NET1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ATP11B-NET1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource