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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FAM168A-SYT12 (FusionGDB2 ID:HG23201TG91683)

Fusion Gene Summary for FAM168A-SYT12

check button Fusion gene summary
Fusion gene informationFusion gene name: FAM168A-SYT12
Fusion gene ID: hg23201tg91683
HgeneTgene
Gene symbol

FAM168A

SYT12

Gene ID

23201

91683

Gene namefamily with sequence similarity 168 member Asynaptotagmin 12
SynonymsKIAA0280|TCRP1SYT11|sytXII
Cytomap('FAM168A')('SYT12')

11q13.4

11q13.2

Type of geneprotein-codingprotein-coding
Descriptionprotein FAM168Atongue cancer chemotherapy resistance-associated protein 1synaptotagmin-12synaptotagmin-XII
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000064778, ENST00000356467, 
ENST00000450446, 
Fusion gene scores* DoF score27 X 14 X 13=49145 X 7 X 6=210
# samples 418
** MAII scorelog2(41/4914*10)=-3.58320204285672
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/210*10)=-1.39231742277876
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FAM168A [Title/Abstract] AND SYT12 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFAM168A(73122439)-SYT12(66807282), # samples:2
Anticipated loss of major functional domain due to fusion event.FAM168A-SYT12 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
FAM168A-SYT12 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFAM168A

GO:1905053

positive regulation of base-excision repair

25260657


check buttonFusion gene breakpoints across FAM168A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across SYT12 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-HS-A5N8-01AFAM168Achr11

73122439

-SYT12chr11

66807282

+


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Fusion Gene ORF analysis for FAM168A-SYT12

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000064778ENST00000526281FAM168Achr11

73122439

-SYT12chr11

66807282

+
5CDS-3UTRENST00000356467ENST00000526281FAM168Achr11

73122439

-SYT12chr11

66807282

+
In-frameENST00000064778ENST00000393946FAM168Achr11

73122439

-SYT12chr11

66807282

+
In-frameENST00000064778ENST00000525457FAM168Achr11

73122439

-SYT12chr11

66807282

+
In-frameENST00000064778ENST00000527043FAM168Achr11

73122439

-SYT12chr11

66807282

+
In-frameENST00000356467ENST00000393946FAM168Achr11

73122439

-SYT12chr11

66807282

+
In-frameENST00000356467ENST00000525457FAM168Achr11

73122439

-SYT12chr11

66807282

+
In-frameENST00000356467ENST00000527043FAM168Achr11

73122439

-SYT12chr11

66807282

+
intron-3CDSENST00000450446ENST00000393946FAM168Achr11

73122439

-SYT12chr11

66807282

+
intron-3CDSENST00000450446ENST00000525457FAM168Achr11

73122439

-SYT12chr11

66807282

+
intron-3CDSENST00000450446ENST00000527043FAM168Achr11

73122439

-SYT12chr11

66807282

+
intron-3UTRENST00000450446ENST00000526281FAM168Achr11

73122439

-SYT12chr11

66807282

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000064778FAM168Achr1173122439-ENST00000393946SYT12chr1166807282+38767321651769534
ENST00000064778FAM168Achr1173122439-ENST00000525457SYT12chr1166807282+19527321651769534
ENST00000064778FAM168Achr1173122439-ENST00000527043SYT12chr1166807282+20267321651769534
ENST00000356467FAM168Achr1173122439-ENST00000393946SYT12chr1166807282+38436991591736525
ENST00000356467FAM168Achr1173122439-ENST00000525457SYT12chr1166807282+19196991591736525
ENST00000356467FAM168Achr1173122439-ENST00000527043SYT12chr1166807282+19936991591736525

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000064778ENST00000393946FAM168Achr1173122439-SYT12chr1166807282+0.0100212780.9899787
ENST00000064778ENST00000525457FAM168Achr1173122439-SYT12chr1166807282+0.0105831620.9894168
ENST00000064778ENST00000527043FAM168Achr1173122439-SYT12chr1166807282+0.010168290.9898317
ENST00000356467ENST00000393946FAM168Achr1173122439-SYT12chr1166807282+0.0159181360.98408186
ENST00000356467ENST00000525457FAM168Achr1173122439-SYT12chr1166807282+0.0164917880.9835082
ENST00000356467ENST00000527043FAM168Achr1173122439-SYT12chr1166807282+0.015818880.98418117

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Fusion Genomic Features for FAM168A-SYT12


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
FAM168Achr1173122438-SYT12chr1166807281+1.37E-060.99999857
FAM168Achr1173122438-SYT12chr1166807281+1.37E-060.99999857

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for FAM168A-SYT12


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:73122439/chr11:66807282)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSYT12chr11:73122439chr11:66807282ENST00000393946511152_27276422.0DomainC2 1
TgeneSYT12chr11:73122439chr11:66807282ENST00000393946511283_41676422.0DomainC2 2
TgeneSYT12chr11:73122439chr11:66807282ENST0000052545728152_27276422.0DomainC2 1
TgeneSYT12chr11:73122439chr11:66807282ENST0000052545728283_41676422.0DomainC2 2
TgeneSYT12chr11:73122439chr11:66807282ENST0000052704328152_27276422.0DomainC2 1
TgeneSYT12chr11:73122439chr11:66807282ENST0000052704328283_41676422.0DomainC2 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSYT12chr11:73122439chr11:66807282ENST000003939465111_1876422.0Topological domainVesicular
TgeneSYT12chr11:73122439chr11:66807282ENST0000039394651140_42176422.0Topological domainCytoplasmic
TgeneSYT12chr11:73122439chr11:66807282ENST00000525457281_1876422.0Topological domainVesicular
TgeneSYT12chr11:73122439chr11:66807282ENST000005254572840_42176422.0Topological domainCytoplasmic
TgeneSYT12chr11:73122439chr11:66807282ENST00000527043281_1876422.0Topological domainVesicular
TgeneSYT12chr11:73122439chr11:66807282ENST000005270432840_42176422.0Topological domainCytoplasmic
TgeneSYT12chr11:73122439chr11:66807282ENST0000039394651119_3976422.0TransmembraneHelical
TgeneSYT12chr11:73122439chr11:66807282ENST000005254572819_3976422.0TransmembraneHelical
TgeneSYT12chr11:73122439chr11:66807282ENST000005270432819_3976422.0TransmembraneHelical


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Fusion Gene Sequence for FAM168A-SYT12


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>28670_28670_1_FAM168A-SYT12_FAM168A_chr11_73122439_ENST00000064778_SYT12_chr11_66807282_ENST00000393946_length(transcript)=3876nt_BP=732nt
CCTTCTGAGCGGTCCCCCGCCTCCTCCCTCCGCCTCCTCCTCCCTCGCCCGCAGCCGAGCGTCCCCTCCCCCCACCCGTCGGGCTCCTCG
GCGGCTACTGCAGAGGATTCAGAGCCGAGTCGCTGAGGAGGAGGCTCCGGTCCCCGCGCGCCATCCGCCACCCTACTGGACACGGGCGAG
AGCGTCGCCGCCGTAGCCTCCGGAGAAGACAAGGGCATCGCCGCCTCAGCCGCCGCCGCCGCCGTTTTCGCCTGCAGCTGCTCACCGGAT
CCTCAGTCTTCCACAATGAACCCTGTTTACAGCCCCGTGCAGCCTGGGGCTCCTTATGGCAACCCTAAGAACATGGCCTACACGGGTTAC
CCCACAGCCTATCCAGCAGCTGCCCCTGCCTACAATCCCAGCCTGTACCCCACCAATAGTCCCAGTTATGCTCCAGAGTTTCAGTTCCTG
CATTCAGCTTATGCAACTCTGCTGATGAAACAGGCCTGGCCACAGAACTCGTCTTCCTGTGGCACTGAAGGCACCTTCCACCTCCCAGTG
GACACCGGGACCGAGAACCGAACTTACCAAGCATCCTCTGCGGCTTTCAGATATACTGCGGGGACACCATACAAGGTCCCACCGACCCAG
AGTAACACTGCTCCACCCCCCTACTCCCCATCACCCAACCCCTATCAGACGGCCATGTATCCAATCAGAAGTGCCTACCCCCAGCAGAAT
CTGTATGCCCAGAGAGTGCCTGCCTGGAATGCCCAGCGGGCCAGCACGCGGGGACCACCCAGCCGCAAAGGCAGTCTCAGCATTGAGGAC
ACCTTTGAGAGCATCAGTGAACTGGGGCCTCTGGAGCTGATGGGCCGGGAGTTGGACCTGGCCCCCTATGGGACCCTCCGGAAGTCCCAG
TCGGCCGACTCCCTGAACTCCATCTCCTCCGTGAGCAACACCTTTGGGCAGGACTTCACACTGGGCCAGGTGGAGGTGAGCATGGAGTAC
GACACTGCCTCCCACACGCTGAACGTGGCGGTGATGCAGGGCAAGGACCTCCTGGAGCGGGAGGAGGCCAGCTTCGAGTCCTGCTTCATG
CGCGTCAGCCTGCTGCCGGACGAGCAGATCGTGGGCATTTCTCGGATCCAGAGAAATGCCTACTCCATCTTCTTTGATGAGAAGTTCTCC
ATCCCCCTGGATCCCACAGCCCTGGAGGAGAAGAGCCTGCGGTTTTCTGTATTTGGCATCGATGAGGATGAGCGCAACGTCAGCACGGGG
GTGGTGGAGCTGAAGCTTTCTGTGCTTGACCTCCCGCTGCAGCCCTTCAGTGGCTGGCTCTATTTACAGGACCAGAACAAGGCCGCCGAT
GCTGTGGGGGAGATCCTGCTCTCCCTCAGCTACCTCCCCACAGCCGAGCGCCTCACCGTGGTCGTGGTTAAGGCCAAGAACCTCATCTGG
ACCAACGACAAGACCACAGCGGACCCCTTCGTCAAGGTGTACCTGCTGCAGGATGGGAGGAAGATGAGCAAAAAGAAGACAGCCGTGAAG
AGGGATGACCCCAACCCGGTGTTCAACGAAGCCATGATCTTCTCGGTGCCAGCCATTGTGCTCCAGGACCTGTCTCTCCGCGTGACGGTG
GCTGAGAGCAGCAGCGACGGCCGTGGGGACAACGTGGGCCATGTCATCATTGGGCCGTCAGCCAGTGGCATGGGAACCACACATTGGAAC
CAGATGTTGGCCACGCTGCGCAGGCCCGTGTCCATGTGGCACGCTGTCCGGCGAAACTAGCAACCAGGGCGGGCCAGTTGGGCAATGGAG
CTGCTGGAGCCCGGTACCCACTCAGCTCTGTCTGATGCCCTCTCCATAGCCCAGCTGGAGCCGTGAACACTGGGGTCCCCTGGCAGAGTC
CTCATGACCCATCCTGGTCTCTCTGTCCAGATTGCAGCAGAGGAGTGGGCGTGGCTCTGTGTCCAGGGCCCCAGGGTCTGCTCCTGCTGA
GGACCAGCTGTGGCTGGGCCAGGACAGAGGACTCAACCCTGCTCCTCCCGGTAGGCCAGCTGCCGAGCTGGGCTATGTTCTGGAACCCAG
TGAATCTTGGGGGCCAGGCACTGTGCTAGGCACCAGCAGGGGTAACACGAAGAAGACCCGGCCCTTAGGGCATCAGGAAGACTAGCTCCC
CTGCCCCGGAGGATCTGCTCAGTGCTGATGGCAGCCCAGCTGTGTGGACTCAGGGGGCTCTGAGGGCTAGGGAAACAGGAAGGGCCTCTT
TGACAAGGTAGGAGCTGTGCTTGGAGGGGCAGGAAAAGAACTGAGCATGTCGCAGGCAGCGGGCCCAGCCTGAGCAATGGCAGGATGTGA
ACTTCCCCATCGCAAATGCAGTTCTCAGCCCACTGCAGTGGATACAAGGAAGGGCCTTTCTCGGGGCCGGAGAAGAGACCAAGAGACCAG
GCCCGGGCAGCAGCCTACCGGCCACGTGGAACACTGGCTCCGGAGTTATTCTCTGTCAAATCTACTCCCCGGACCTCAACCATGGCAAGA
ACCAGAGGTCCAAAGAGGCCCAGACCCAGGTCCTTGTGCTCAGTCCTGCGCAAACCAGGCCCAGACCCTGCAAGCATTTGTTGATGCCCT
TGCAGGCCCACTGGGAGAAAGATGCCTCAGGCAGGTCTCAGCCTGGGGGTGGCAGGGGTGGGGCAGAGAGAATACTGACAGCAGAGGTCT
TGGTGGGCTGCACGTGCCTGCGAAGATGTGGTGGACAAGGAGGCTCTCGGGCTGGGCCTTGGAGGGGTGGCAGCGGAAGGACAGCCCAGG
TGGCTGAGGCCTGATGGGAAGCCGGGGAAGGCCAGGGTGGAAGGGCGGCTTGAGGGACGCCAGGAGAAGACTGAATGCCAGGCTAGGAAG
GAGGCGGCTCTCGATCACGGGGTGGGTGCCCCCGACACCGGGTCTCCTAGCTTGAGTTCCCTAGAAGCGAAATCTGAGAGGGGGATTCTG
GGGCAAGTAGTTTCTTGCGGGTGAGTGTTCTCAGAGAAACTTACCAGATCAAGAAAGGGAGCTCAGGCTGGATGGAGGAAGCCACGCAAG
TGTGGCTTCAAGATCCATCGCCTTGGCCTGATCGCTGTGGGGGCAGGGGCCTGGAGTACGAGGGGCACCCTGGGGGCTCCCACCCAGAAG
CAGAGGGGCTGGGCTGTTGCACCTCTACTGGCATCAGTCTTTGGTTACCCCCCAGCCCCAGTAGGAGGAGAGCAGGCAGAGCTTGTCATC
CCCAGCCTGGTGTCCCGCAGTCCCAGGAAGCCGCTTCTTGCCTTCATGGCTGAGTGCTGGGAAGGGCTGAGCTCACCCAGGCCAGCAGGT
GGGGTATCATCTGCTCGGTGGGGCCACCCACAGGTGACAGCATGGACCCTCAGGCTGGCTGCCCCTGTTCCTTGGTCCATAACTGGTGAG
CTATGGAGACCCAGGCCAACAAATTATCCCCAGTGATATGGGGGGAGGAGGGGCTAGAACAAGGGCCCAGGGGACTGGAGGCAGGATGGT
GGCTTTCCCTACCTGACACAGCCATGGCCCAGCCCCAAGGCCAGGCTGTCTACCCTATGGCCACAGCAGGAGGTCAGCCCAGGGCCAGGA
GACACATGGCTGGACAAGGCTTTGCAGCCTGGGAGACCCCGACTTTCTCTAACCCAGTGGCTGTGCGGTGCAGGCCACTGACTCCCCCCC
TGCCCTCTCCCCTCTCTCCCTCCCCCTAACTGCATGACATGTTAACTGTGTGCCCAGGACAGCCGTGGTGGGGACCGGGTATGCCAACTG
GAATGATTCTAGAACCAAAATAAAGTTGGGGCAGGAAGAGGGGGCTTCCAGGGAGCCCTGCTCGGCCCTGAATCACCTTCGTCTCTTCTC

>28670_28670_1_FAM168A-SYT12_FAM168A_chr11_73122439_ENST00000064778_SYT12_chr11_66807282_ENST00000393946_length(amino acids)=534AA_BP=189
MDTGESVAAVASGEDKGIAASAAAAAVFACSCSPDPQSSTMNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAP
EFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSA
YPQQNLYAQRVPAWNAQRASTRGPPSRKGSLSIEDTFESISELGPLELMGRELDLAPYGTLRKSQSADSLNSISSVSNTFGQDFTLGQVE
VSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDER
NVSTGVVELKLSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKK

--------------------------------------------------------------
>28670_28670_2_FAM168A-SYT12_FAM168A_chr11_73122439_ENST00000064778_SYT12_chr11_66807282_ENST00000525457_length(transcript)=1952nt_BP=732nt
CCTTCTGAGCGGTCCCCCGCCTCCTCCCTCCGCCTCCTCCTCCCTCGCCCGCAGCCGAGCGTCCCCTCCCCCCACCCGTCGGGCTCCTCG
GCGGCTACTGCAGAGGATTCAGAGCCGAGTCGCTGAGGAGGAGGCTCCGGTCCCCGCGCGCCATCCGCCACCCTACTGGACACGGGCGAG
AGCGTCGCCGCCGTAGCCTCCGGAGAAGACAAGGGCATCGCCGCCTCAGCCGCCGCCGCCGCCGTTTTCGCCTGCAGCTGCTCACCGGAT
CCTCAGTCTTCCACAATGAACCCTGTTTACAGCCCCGTGCAGCCTGGGGCTCCTTATGGCAACCCTAAGAACATGGCCTACACGGGTTAC
CCCACAGCCTATCCAGCAGCTGCCCCTGCCTACAATCCCAGCCTGTACCCCACCAATAGTCCCAGTTATGCTCCAGAGTTTCAGTTCCTG
CATTCAGCTTATGCAACTCTGCTGATGAAACAGGCCTGGCCACAGAACTCGTCTTCCTGTGGCACTGAAGGCACCTTCCACCTCCCAGTG
GACACCGGGACCGAGAACCGAACTTACCAAGCATCCTCTGCGGCTTTCAGATATACTGCGGGGACACCATACAAGGTCCCACCGACCCAG
AGTAACACTGCTCCACCCCCCTACTCCCCATCACCCAACCCCTATCAGACGGCCATGTATCCAATCAGAAGTGCCTACCCCCAGCAGAAT
CTGTATGCCCAGAGAGTGCCTGCCTGGAATGCCCAGCGGGCCAGCACGCGGGGACCACCCAGCCGCAAAGGCAGTCTCAGCATTGAGGAC
ACCTTTGAGAGCATCAGTGAACTGGGGCCTCTGGAGCTGATGGGCCGGGAGTTGGACCTGGCCCCCTATGGGACCCTCCGGAAGTCCCAG
TCGGCCGACTCCCTGAACTCCATCTCCTCCGTGAGCAACACCTTTGGGCAGGACTTCACACTGGGCCAGGTGGAGGTGAGCATGGAGTAC
GACACTGCCTCCCACACGCTGAACGTGGCGGTGATGCAGGGCAAGGACCTCCTGGAGCGGGAGGAGGCCAGCTTCGAGTCCTGCTTCATG
CGCGTCAGCCTGCTGCCGGACGAGCAGATCGTGGGCATTTCTCGGATCCAGAGAAATGCCTACTCCATCTTCTTTGATGAGAAGTTCTCC
ATCCCCCTGGATCCCACAGCCCTGGAGGAGAAGAGCCTGCGGTTTTCTGTATTTGGCATCGATGAGGATGAGCGCAACGTCAGCACGGGG
GTGGTGGAGCTGAAGCTTTCTGTGCTTGACCTCCCGCTGCAGCCCTTCAGTGGCTGGCTCTATTTACAGGACCAGAACAAGGCCGCCGAT
GCTGTGGGGGAGATCCTGCTCTCCCTCAGCTACCTCCCCACAGCCGAGCGCCTCACCGTGGTCGTGGTTAAGGCCAAGAACCTCATCTGG
ACCAACGACAAGACCACAGCGGACCCCTTCGTCAAGGTGTACCTGCTGCAGGATGGGAGGAAGATGAGCAAAAAGAAGACAGCCGTGAAG
AGGGATGACCCCAACCCGGTGTTCAACGAAGCCATGATCTTCTCGGTGCCAGCCATTGTGCTCCAGGACCTGTCTCTCCGCGTGACGGTG
GCTGAGAGCAGCAGCGACGGCCGTGGGGACAACGTGGGCCATGTCATCATTGGGCCGTCAGCCAGTGGCATGGGAACCACACATTGGAAC
CAGATGTTGGCCACGCTGCGCAGGCCCGTGTCCATGTGGCACGCTGTCCGGCGAAACTAGCAACCAGGGCGGGCCAGTTGGGCAATGGAG
CTGCTGGAGCCCGGTACCCACTCAGCTCTGTCTGATGCCCTCTCCATAGCCCAGCTGGAGCCGTGAACACTGGGGTCCCCTGGCAGAGTC

>28670_28670_2_FAM168A-SYT12_FAM168A_chr11_73122439_ENST00000064778_SYT12_chr11_66807282_ENST00000525457_length(amino acids)=534AA_BP=189
MDTGESVAAVASGEDKGIAASAAAAAVFACSCSPDPQSSTMNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAP
EFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSA
YPQQNLYAQRVPAWNAQRASTRGPPSRKGSLSIEDTFESISELGPLELMGRELDLAPYGTLRKSQSADSLNSISSVSNTFGQDFTLGQVE
VSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDER
NVSTGVVELKLSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKK

--------------------------------------------------------------
>28670_28670_3_FAM168A-SYT12_FAM168A_chr11_73122439_ENST00000064778_SYT12_chr11_66807282_ENST00000527043_length(transcript)=2026nt_BP=732nt
CCTTCTGAGCGGTCCCCCGCCTCCTCCCTCCGCCTCCTCCTCCCTCGCCCGCAGCCGAGCGTCCCCTCCCCCCACCCGTCGGGCTCCTCG
GCGGCTACTGCAGAGGATTCAGAGCCGAGTCGCTGAGGAGGAGGCTCCGGTCCCCGCGCGCCATCCGCCACCCTACTGGACACGGGCGAG
AGCGTCGCCGCCGTAGCCTCCGGAGAAGACAAGGGCATCGCCGCCTCAGCCGCCGCCGCCGCCGTTTTCGCCTGCAGCTGCTCACCGGAT
CCTCAGTCTTCCACAATGAACCCTGTTTACAGCCCCGTGCAGCCTGGGGCTCCTTATGGCAACCCTAAGAACATGGCCTACACGGGTTAC
CCCACAGCCTATCCAGCAGCTGCCCCTGCCTACAATCCCAGCCTGTACCCCACCAATAGTCCCAGTTATGCTCCAGAGTTTCAGTTCCTG
CATTCAGCTTATGCAACTCTGCTGATGAAACAGGCCTGGCCACAGAACTCGTCTTCCTGTGGCACTGAAGGCACCTTCCACCTCCCAGTG
GACACCGGGACCGAGAACCGAACTTACCAAGCATCCTCTGCGGCTTTCAGATATACTGCGGGGACACCATACAAGGTCCCACCGACCCAG
AGTAACACTGCTCCACCCCCCTACTCCCCATCACCCAACCCCTATCAGACGGCCATGTATCCAATCAGAAGTGCCTACCCCCAGCAGAAT
CTGTATGCCCAGAGAGTGCCTGCCTGGAATGCCCAGCGGGCCAGCACGCGGGGACCACCCAGCCGCAAAGGCAGTCTCAGCATTGAGGAC
ACCTTTGAGAGCATCAGTGAACTGGGGCCTCTGGAGCTGATGGGCCGGGAGTTGGACCTGGCCCCCTATGGGACCCTCCGGAAGTCCCAG
TCGGCCGACTCCCTGAACTCCATCTCCTCCGTGAGCAACACCTTTGGGCAGGACTTCACACTGGGCCAGGTGGAGGTGAGCATGGAGTAC
GACACTGCCTCCCACACGCTGAACGTGGCGGTGATGCAGGGCAAGGACCTCCTGGAGCGGGAGGAGGCCAGCTTCGAGTCCTGCTTCATG
CGCGTCAGCCTGCTGCCGGACGAGCAGATCGTGGGCATTTCTCGGATCCAGAGAAATGCCTACTCCATCTTCTTTGATGAGAAGTTCTCC
ATCCCCCTGGATCCCACAGCCCTGGAGGAGAAGAGCCTGCGGTTTTCTGTATTTGGCATCGATGAGGATGAGCGCAACGTCAGCACGGGG
GTGGTGGAGCTGAAGCTTTCTGTGCTTGACCTCCCGCTGCAGCCCTTCAGTGGCTGGCTCTATTTACAGGACCAGAACAAGGCCGCCGAT
GCTGTGGGGGAGATCCTGCTCTCCCTCAGCTACCTCCCCACAGCCGAGCGCCTCACCGTGGTCGTGGTTAAGGCCAAGAACCTCATCTGG
ACCAACGACAAGACCACAGCGGACCCCTTCGTCAAGGTGTACCTGCTGCAGGATGGGAGGAAGATGAGCAAAAAGAAGACAGCCGTGAAG
AGGGATGACCCCAACCCGGTGTTCAACGAAGCCATGATCTTCTCGGTGCCAGCCATTGTGCTCCAGGACCTGTCTCTCCGCGTGACGGTG
GCTGAGAGCAGCAGCGACGGCCGTGGGGACAACGTGGGCCATGTCATCATTGGGCCGTCAGCCAGTGGCATGGGAACCACACATTGGAAC
CAGATGTTGGCCACGCTGCGCAGGCCCGTGTCCATGTGGCACGCTGTCCGGCGAAACTAGCAACCAGGGCGGGCCAGTTGGGCAATGGAG
CTGCTGGAGCCCGGTACCCACTCAGCTCTGTCTGATGCCCTCTCCATAGCCCAGCTGGAGCCGTGAACACTGGGGTCCCCTGGCAGAGTC
CTCATGACCCATCCTGGTCTCTCTGTCCAGATTGCAGCAGAGGAGTGGGCGTGGCTCTGTGTCCAGGGCCCCAGGGTCTGCTCCTGCTGA

>28670_28670_3_FAM168A-SYT12_FAM168A_chr11_73122439_ENST00000064778_SYT12_chr11_66807282_ENST00000527043_length(amino acids)=534AA_BP=189
MDTGESVAAVASGEDKGIAASAAAAAVFACSCSPDPQSSTMNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAP
EFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSA
YPQQNLYAQRVPAWNAQRASTRGPPSRKGSLSIEDTFESISELGPLELMGRELDLAPYGTLRKSQSADSLNSISSVSNTFGQDFTLGQVE
VSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDER
NVSTGVVELKLSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKK

--------------------------------------------------------------
>28670_28670_4_FAM168A-SYT12_FAM168A_chr11_73122439_ENST00000356467_SYT12_chr11_66807282_ENST00000393946_length(transcript)=3843nt_BP=699nt
GAGCGGTCCCCCGCCTCCTCCCTCCGCCTCCTCCTCCCTCGCCCGCAGCCGAGCGTCCCCTCCCCCCACCCGTCGGGCTCCTCGGCGGCT
ACTGCAGAGGATTCAGAGCCGAGTCGCTGAGGAGGAGGCTCCGGTCCCCGCGCGCCATCCGCCACCCTACTGGACACGGGCGAGAGCGTC
GCCGCCGTAGCCTCCGGAGAAGACAAGGGCATCGCCGCCTCAGCCGCCGCCGCCGCCGTTTTCGCCTGCAGCTGCTCACCGGATCCTCAG
TCTTCCACAATGAACCCTGTTTACAGCCCCGTGCAGCCTGGGGCTCCTTATGGCAACCCTAAGAACATGGCCTACACGGGTTACCCCACA
GCCTATCCAGCAGCTGCCCCTGCCTACAATCCCAGCCTGTACCCCACCAATAGTCCCAGTTATGCTCCAGCAACTCTGCTGATGAAACAG
GCCTGGCCACAGAACTCGTCTTCCTGTGGCACTGAAGGCACCTTCCACCTCCCAGTGGACACCGGGACCGAGAACCGAACTTACCAAGCA
TCCTCTGCGGCTTTCAGATATACTGCGGGGACACCATACAAGGTCCCACCGACCCAGAGTAACACTGCTCCACCCCCCTACTCCCCATCA
CCCAACCCCTATCAGACGGCCATGTATCCAATCAGAAGTGCCTACCCCCAGCAGAATCTGTATGCCCAGAGAGTGCCTGCCTGGAATGCC
CAGCGGGCCAGCACGCGGGGACCACCCAGCCGCAAAGGCAGTCTCAGCATTGAGGACACCTTTGAGAGCATCAGTGAACTGGGGCCTCTG
GAGCTGATGGGCCGGGAGTTGGACCTGGCCCCCTATGGGACCCTCCGGAAGTCCCAGTCGGCCGACTCCCTGAACTCCATCTCCTCCGTG
AGCAACACCTTTGGGCAGGACTTCACACTGGGCCAGGTGGAGGTGAGCATGGAGTACGACACTGCCTCCCACACGCTGAACGTGGCGGTG
ATGCAGGGCAAGGACCTCCTGGAGCGGGAGGAGGCCAGCTTCGAGTCCTGCTTCATGCGCGTCAGCCTGCTGCCGGACGAGCAGATCGTG
GGCATTTCTCGGATCCAGAGAAATGCCTACTCCATCTTCTTTGATGAGAAGTTCTCCATCCCCCTGGATCCCACAGCCCTGGAGGAGAAG
AGCCTGCGGTTTTCTGTATTTGGCATCGATGAGGATGAGCGCAACGTCAGCACGGGGGTGGTGGAGCTGAAGCTTTCTGTGCTTGACCTC
CCGCTGCAGCCCTTCAGTGGCTGGCTCTATTTACAGGACCAGAACAAGGCCGCCGATGCTGTGGGGGAGATCCTGCTCTCCCTCAGCTAC
CTCCCCACAGCCGAGCGCCTCACCGTGGTCGTGGTTAAGGCCAAGAACCTCATCTGGACCAACGACAAGACCACAGCGGACCCCTTCGTC
AAGGTGTACCTGCTGCAGGATGGGAGGAAGATGAGCAAAAAGAAGACAGCCGTGAAGAGGGATGACCCCAACCCGGTGTTCAACGAAGCC
ATGATCTTCTCGGTGCCAGCCATTGTGCTCCAGGACCTGTCTCTCCGCGTGACGGTGGCTGAGAGCAGCAGCGACGGCCGTGGGGACAAC
GTGGGCCATGTCATCATTGGGCCGTCAGCCAGTGGCATGGGAACCACACATTGGAACCAGATGTTGGCCACGCTGCGCAGGCCCGTGTCC
ATGTGGCACGCTGTCCGGCGAAACTAGCAACCAGGGCGGGCCAGTTGGGCAATGGAGCTGCTGGAGCCCGGTACCCACTCAGCTCTGTCT
GATGCCCTCTCCATAGCCCAGCTGGAGCCGTGAACACTGGGGTCCCCTGGCAGAGTCCTCATGACCCATCCTGGTCTCTCTGTCCAGATT
GCAGCAGAGGAGTGGGCGTGGCTCTGTGTCCAGGGCCCCAGGGTCTGCTCCTGCTGAGGACCAGCTGTGGCTGGGCCAGGACAGAGGACT
CAACCCTGCTCCTCCCGGTAGGCCAGCTGCCGAGCTGGGCTATGTTCTGGAACCCAGTGAATCTTGGGGGCCAGGCACTGTGCTAGGCAC
CAGCAGGGGTAACACGAAGAAGACCCGGCCCTTAGGGCATCAGGAAGACTAGCTCCCCTGCCCCGGAGGATCTGCTCAGTGCTGATGGCA
GCCCAGCTGTGTGGACTCAGGGGGCTCTGAGGGCTAGGGAAACAGGAAGGGCCTCTTTGACAAGGTAGGAGCTGTGCTTGGAGGGGCAGG
AAAAGAACTGAGCATGTCGCAGGCAGCGGGCCCAGCCTGAGCAATGGCAGGATGTGAACTTCCCCATCGCAAATGCAGTTCTCAGCCCAC
TGCAGTGGATACAAGGAAGGGCCTTTCTCGGGGCCGGAGAAGAGACCAAGAGACCAGGCCCGGGCAGCAGCCTACCGGCCACGTGGAACA
CTGGCTCCGGAGTTATTCTCTGTCAAATCTACTCCCCGGACCTCAACCATGGCAAGAACCAGAGGTCCAAAGAGGCCCAGACCCAGGTCC
TTGTGCTCAGTCCTGCGCAAACCAGGCCCAGACCCTGCAAGCATTTGTTGATGCCCTTGCAGGCCCACTGGGAGAAAGATGCCTCAGGCA
GGTCTCAGCCTGGGGGTGGCAGGGGTGGGGCAGAGAGAATACTGACAGCAGAGGTCTTGGTGGGCTGCACGTGCCTGCGAAGATGTGGTG
GACAAGGAGGCTCTCGGGCTGGGCCTTGGAGGGGTGGCAGCGGAAGGACAGCCCAGGTGGCTGAGGCCTGATGGGAAGCCGGGGAAGGCC
AGGGTGGAAGGGCGGCTTGAGGGACGCCAGGAGAAGACTGAATGCCAGGCTAGGAAGGAGGCGGCTCTCGATCACGGGGTGGGTGCCCCC
GACACCGGGTCTCCTAGCTTGAGTTCCCTAGAAGCGAAATCTGAGAGGGGGATTCTGGGGCAAGTAGTTTCTTGCGGGTGAGTGTTCTCA
GAGAAACTTACCAGATCAAGAAAGGGAGCTCAGGCTGGATGGAGGAAGCCACGCAAGTGTGGCTTCAAGATCCATCGCCTTGGCCTGATC
GCTGTGGGGGCAGGGGCCTGGAGTACGAGGGGCACCCTGGGGGCTCCCACCCAGAAGCAGAGGGGCTGGGCTGTTGCACCTCTACTGGCA
TCAGTCTTTGGTTACCCCCCAGCCCCAGTAGGAGGAGAGCAGGCAGAGCTTGTCATCCCCAGCCTGGTGTCCCGCAGTCCCAGGAAGCCG
CTTCTTGCCTTCATGGCTGAGTGCTGGGAAGGGCTGAGCTCACCCAGGCCAGCAGGTGGGGTATCATCTGCTCGGTGGGGCCACCCACAG
GTGACAGCATGGACCCTCAGGCTGGCTGCCCCTGTTCCTTGGTCCATAACTGGTGAGCTATGGAGACCCAGGCCAACAAATTATCCCCAG
TGATATGGGGGGAGGAGGGGCTAGAACAAGGGCCCAGGGGACTGGAGGCAGGATGGTGGCTTTCCCTACCTGACACAGCCATGGCCCAGC
CCCAAGGCCAGGCTGTCTACCCTATGGCCACAGCAGGAGGTCAGCCCAGGGCCAGGAGACACATGGCTGGACAAGGCTTTGCAGCCTGGG
AGACCCCGACTTTCTCTAACCCAGTGGCTGTGCGGTGCAGGCCACTGACTCCCCCCCTGCCCTCTCCCCTCTCTCCCTCCCCCTAACTGC
ATGACATGTTAACTGTGTGCCCAGGACAGCCGTGGTGGGGACCGGGTATGCCAACTGGAATGATTCTAGAACCAAAATAAAGTTGGGGCA

>28670_28670_4_FAM168A-SYT12_FAM168A_chr11_73122439_ENST00000356467_SYT12_chr11_66807282_ENST00000393946_length(amino acids)=525AA_BP=180
MDTGESVAAVASGEDKGIAASAAAAAVFACSCSPDPQSSTMNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAP
ATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQ
RVPAWNAQRASTRGPPSRKGSLSIEDTFESISELGPLELMGRELDLAPYGTLRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMEYDTAS
HTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVEL
KLSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDP

--------------------------------------------------------------
>28670_28670_5_FAM168A-SYT12_FAM168A_chr11_73122439_ENST00000356467_SYT12_chr11_66807282_ENST00000525457_length(transcript)=1919nt_BP=699nt
GAGCGGTCCCCCGCCTCCTCCCTCCGCCTCCTCCTCCCTCGCCCGCAGCCGAGCGTCCCCTCCCCCCACCCGTCGGGCTCCTCGGCGGCT
ACTGCAGAGGATTCAGAGCCGAGTCGCTGAGGAGGAGGCTCCGGTCCCCGCGCGCCATCCGCCACCCTACTGGACACGGGCGAGAGCGTC
GCCGCCGTAGCCTCCGGAGAAGACAAGGGCATCGCCGCCTCAGCCGCCGCCGCCGCCGTTTTCGCCTGCAGCTGCTCACCGGATCCTCAG
TCTTCCACAATGAACCCTGTTTACAGCCCCGTGCAGCCTGGGGCTCCTTATGGCAACCCTAAGAACATGGCCTACACGGGTTACCCCACA
GCCTATCCAGCAGCTGCCCCTGCCTACAATCCCAGCCTGTACCCCACCAATAGTCCCAGTTATGCTCCAGCAACTCTGCTGATGAAACAG
GCCTGGCCACAGAACTCGTCTTCCTGTGGCACTGAAGGCACCTTCCACCTCCCAGTGGACACCGGGACCGAGAACCGAACTTACCAAGCA
TCCTCTGCGGCTTTCAGATATACTGCGGGGACACCATACAAGGTCCCACCGACCCAGAGTAACACTGCTCCACCCCCCTACTCCCCATCA
CCCAACCCCTATCAGACGGCCATGTATCCAATCAGAAGTGCCTACCCCCAGCAGAATCTGTATGCCCAGAGAGTGCCTGCCTGGAATGCC
CAGCGGGCCAGCACGCGGGGACCACCCAGCCGCAAAGGCAGTCTCAGCATTGAGGACACCTTTGAGAGCATCAGTGAACTGGGGCCTCTG
GAGCTGATGGGCCGGGAGTTGGACCTGGCCCCCTATGGGACCCTCCGGAAGTCCCAGTCGGCCGACTCCCTGAACTCCATCTCCTCCGTG
AGCAACACCTTTGGGCAGGACTTCACACTGGGCCAGGTGGAGGTGAGCATGGAGTACGACACTGCCTCCCACACGCTGAACGTGGCGGTG
ATGCAGGGCAAGGACCTCCTGGAGCGGGAGGAGGCCAGCTTCGAGTCCTGCTTCATGCGCGTCAGCCTGCTGCCGGACGAGCAGATCGTG
GGCATTTCTCGGATCCAGAGAAATGCCTACTCCATCTTCTTTGATGAGAAGTTCTCCATCCCCCTGGATCCCACAGCCCTGGAGGAGAAG
AGCCTGCGGTTTTCTGTATTTGGCATCGATGAGGATGAGCGCAACGTCAGCACGGGGGTGGTGGAGCTGAAGCTTTCTGTGCTTGACCTC
CCGCTGCAGCCCTTCAGTGGCTGGCTCTATTTACAGGACCAGAACAAGGCCGCCGATGCTGTGGGGGAGATCCTGCTCTCCCTCAGCTAC
CTCCCCACAGCCGAGCGCCTCACCGTGGTCGTGGTTAAGGCCAAGAACCTCATCTGGACCAACGACAAGACCACAGCGGACCCCTTCGTC
AAGGTGTACCTGCTGCAGGATGGGAGGAAGATGAGCAAAAAGAAGACAGCCGTGAAGAGGGATGACCCCAACCCGGTGTTCAACGAAGCC
ATGATCTTCTCGGTGCCAGCCATTGTGCTCCAGGACCTGTCTCTCCGCGTGACGGTGGCTGAGAGCAGCAGCGACGGCCGTGGGGACAAC
GTGGGCCATGTCATCATTGGGCCGTCAGCCAGTGGCATGGGAACCACACATTGGAACCAGATGTTGGCCACGCTGCGCAGGCCCGTGTCC
ATGTGGCACGCTGTCCGGCGAAACTAGCAACCAGGGCGGGCCAGTTGGGCAATGGAGCTGCTGGAGCCCGGTACCCACTCAGCTCTGTCT
GATGCCCTCTCCATAGCCCAGCTGGAGCCGTGAACACTGGGGTCCCCTGGCAGAGTCCTCATGACCCATCCTGGTCTCTCTGTCCAGATT

>28670_28670_5_FAM168A-SYT12_FAM168A_chr11_73122439_ENST00000356467_SYT12_chr11_66807282_ENST00000525457_length(amino acids)=525AA_BP=180
MDTGESVAAVASGEDKGIAASAAAAAVFACSCSPDPQSSTMNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAP
ATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQ
RVPAWNAQRASTRGPPSRKGSLSIEDTFESISELGPLELMGRELDLAPYGTLRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMEYDTAS
HTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVEL
KLSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDP

--------------------------------------------------------------
>28670_28670_6_FAM168A-SYT12_FAM168A_chr11_73122439_ENST00000356467_SYT12_chr11_66807282_ENST00000527043_length(transcript)=1993nt_BP=699nt
GAGCGGTCCCCCGCCTCCTCCCTCCGCCTCCTCCTCCCTCGCCCGCAGCCGAGCGTCCCCTCCCCCCACCCGTCGGGCTCCTCGGCGGCT
ACTGCAGAGGATTCAGAGCCGAGTCGCTGAGGAGGAGGCTCCGGTCCCCGCGCGCCATCCGCCACCCTACTGGACACGGGCGAGAGCGTC
GCCGCCGTAGCCTCCGGAGAAGACAAGGGCATCGCCGCCTCAGCCGCCGCCGCCGCCGTTTTCGCCTGCAGCTGCTCACCGGATCCTCAG
TCTTCCACAATGAACCCTGTTTACAGCCCCGTGCAGCCTGGGGCTCCTTATGGCAACCCTAAGAACATGGCCTACACGGGTTACCCCACA
GCCTATCCAGCAGCTGCCCCTGCCTACAATCCCAGCCTGTACCCCACCAATAGTCCCAGTTATGCTCCAGCAACTCTGCTGATGAAACAG
GCCTGGCCACAGAACTCGTCTTCCTGTGGCACTGAAGGCACCTTCCACCTCCCAGTGGACACCGGGACCGAGAACCGAACTTACCAAGCA
TCCTCTGCGGCTTTCAGATATACTGCGGGGACACCATACAAGGTCCCACCGACCCAGAGTAACACTGCTCCACCCCCCTACTCCCCATCA
CCCAACCCCTATCAGACGGCCATGTATCCAATCAGAAGTGCCTACCCCCAGCAGAATCTGTATGCCCAGAGAGTGCCTGCCTGGAATGCC
CAGCGGGCCAGCACGCGGGGACCACCCAGCCGCAAAGGCAGTCTCAGCATTGAGGACACCTTTGAGAGCATCAGTGAACTGGGGCCTCTG
GAGCTGATGGGCCGGGAGTTGGACCTGGCCCCCTATGGGACCCTCCGGAAGTCCCAGTCGGCCGACTCCCTGAACTCCATCTCCTCCGTG
AGCAACACCTTTGGGCAGGACTTCACACTGGGCCAGGTGGAGGTGAGCATGGAGTACGACACTGCCTCCCACACGCTGAACGTGGCGGTG
ATGCAGGGCAAGGACCTCCTGGAGCGGGAGGAGGCCAGCTTCGAGTCCTGCTTCATGCGCGTCAGCCTGCTGCCGGACGAGCAGATCGTG
GGCATTTCTCGGATCCAGAGAAATGCCTACTCCATCTTCTTTGATGAGAAGTTCTCCATCCCCCTGGATCCCACAGCCCTGGAGGAGAAG
AGCCTGCGGTTTTCTGTATTTGGCATCGATGAGGATGAGCGCAACGTCAGCACGGGGGTGGTGGAGCTGAAGCTTTCTGTGCTTGACCTC
CCGCTGCAGCCCTTCAGTGGCTGGCTCTATTTACAGGACCAGAACAAGGCCGCCGATGCTGTGGGGGAGATCCTGCTCTCCCTCAGCTAC
CTCCCCACAGCCGAGCGCCTCACCGTGGTCGTGGTTAAGGCCAAGAACCTCATCTGGACCAACGACAAGACCACAGCGGACCCCTTCGTC
AAGGTGTACCTGCTGCAGGATGGGAGGAAGATGAGCAAAAAGAAGACAGCCGTGAAGAGGGATGACCCCAACCCGGTGTTCAACGAAGCC
ATGATCTTCTCGGTGCCAGCCATTGTGCTCCAGGACCTGTCTCTCCGCGTGACGGTGGCTGAGAGCAGCAGCGACGGCCGTGGGGACAAC
GTGGGCCATGTCATCATTGGGCCGTCAGCCAGTGGCATGGGAACCACACATTGGAACCAGATGTTGGCCACGCTGCGCAGGCCCGTGTCC
ATGTGGCACGCTGTCCGGCGAAACTAGCAACCAGGGCGGGCCAGTTGGGCAATGGAGCTGCTGGAGCCCGGTACCCACTCAGCTCTGTCT
GATGCCCTCTCCATAGCCCAGCTGGAGCCGTGAACACTGGGGTCCCCTGGCAGAGTCCTCATGACCCATCCTGGTCTCTCTGTCCAGATT
GCAGCAGAGGAGTGGGCGTGGCTCTGTGTCCAGGGCCCCAGGGTCTGCTCCTGCTGAGGACCAGCTGTGGCTGGGCCAGGACAGAGGACT

>28670_28670_6_FAM168A-SYT12_FAM168A_chr11_73122439_ENST00000356467_SYT12_chr11_66807282_ENST00000527043_length(amino acids)=525AA_BP=180
MDTGESVAAVASGEDKGIAASAAAAAVFACSCSPDPQSSTMNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAP
ATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQ
RVPAWNAQRASTRGPPSRKGSLSIEDTFESISELGPLELMGRELDLAPYGTLRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMEYDTAS
HTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVEL
KLSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FAM168A-SYT12


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FAM168A-SYT12


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FAM168A-SYT12


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneFAM168AC0024623Malignant neoplasm of stomach1CTD_human
HgeneFAM168AC0038356Stomach Neoplasms1CTD_human
HgeneFAM168AC0235874Disease Exacerbation1CTD_human
HgeneFAM168AC1708349Hereditary Diffuse Gastric Cancer1CTD_human