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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ANKRD12-EPB41L3 (FusionGDB2 ID:HG23253TG23136)

Fusion Gene Summary for ANKRD12-EPB41L3

check button Fusion gene summary
Fusion gene informationFusion gene name: ANKRD12-EPB41L3
Fusion gene ID: hg23253tg23136
HgeneTgene
Gene symbol

ANKRD12

EPB41L3

Gene ID

23253

23136

Gene nameankyrin repeat domain 12erythrocyte membrane protein band 4.1 like 3
SynonymsANCO-2|ANCO1|GAC-1|Nbla001444.1B|DAL-1|DAL1
Cytomap('ANKRD12')('EPB41L3')

18p11.22

18p11.31

Type of geneprotein-codingprotein-coding
Descriptionankyrin repeat domain-containing protein 12ankyrin repeat-containing cofactor 2band 4.1-like protein 3differentially expressed in adenocarcinoma of the lung protein 1
Modification date2020031320200320
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000540578, ENST00000262126, 
ENST00000383440, ENST00000400020, 
Fusion gene scores* DoF score17 X 12 X 9=18364 X 4 X 4=64
# samples 214
** MAII scorelog2(21/1836*10)=-3.12810482574769
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/64*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANKRD12 [Title/Abstract] AND EPB41L3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANKRD12(9182517)-EPB41L3(5489160), # samples:3
Anticipated loss of major functional domain due to fusion event.ANKRD12-EPB41L3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ANKRD12-EPB41L3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ANKRD12-EPB41L3 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ANKRD12-EPB41L3 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ANKRD12 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across EPB41L3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-77-7141-01AANKRD12chr18

9182517

-EPB41L3chr18

5489160

-
ChimerDB4LUSCTCGA-77-7141-01AANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
ChimerDB4LUSCTCGA-77-7141ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-


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Fusion Gene ORF analysis for ANKRD12-EPB41L3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000540578ENST00000341928ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
3UTR-3CDSENST00000540578ENST00000342933ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
3UTR-3CDSENST00000540578ENST00000400111ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
3UTR-3CDSENST00000540578ENST00000540638ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
3UTR-3CDSENST00000540578ENST00000544123ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
3UTR-intronENST00000540578ENST00000427684ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
3UTR-intronENST00000540578ENST00000542146ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
3UTR-intronENST00000540578ENST00000542652ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
5CDS-intronENST00000262126ENST00000427684ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
5CDS-intronENST00000262126ENST00000542146ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
5CDS-intronENST00000262126ENST00000542652ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
5CDS-intronENST00000383440ENST00000427684ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
5CDS-intronENST00000383440ENST00000542146ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
5CDS-intronENST00000383440ENST00000542652ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
5CDS-intronENST00000400020ENST00000427684ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
5CDS-intronENST00000400020ENST00000542146ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
5CDS-intronENST00000400020ENST00000542652ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
Frame-shiftENST00000262126ENST00000342933ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
Frame-shiftENST00000262126ENST00000400111ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
Frame-shiftENST00000262126ENST00000544123ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
Frame-shiftENST00000383440ENST00000342933ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
Frame-shiftENST00000383440ENST00000400111ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
Frame-shiftENST00000383440ENST00000544123ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
Frame-shiftENST00000400020ENST00000342933ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
Frame-shiftENST00000400020ENST00000400111ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
Frame-shiftENST00000400020ENST00000544123ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
In-frameENST00000262126ENST00000341928ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
In-frameENST00000262126ENST00000540638ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
In-frameENST00000383440ENST00000341928ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
In-frameENST00000383440ENST00000540638ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
In-frameENST00000400020ENST00000341928ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-
In-frameENST00000400020ENST00000540638ANKRD12chr18

9182517

+EPB41L3chr18

5489160

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000383440ANKRD12chr189182517+ENST00000341928EPB41L3chr185489160-468734416553256533
ENST00000383440ANKRD12chr189182517+ENST00000540638EPB41L3chr185489160-33123449461782278
ENST00000262126ANKRD12chr189182517+ENST00000341928EPB41L3chr185489160-467032716383239533
ENST00000262126ANKRD12chr189182517+ENST00000540638EPB41L3chr185489160-32953279291765278
ENST00000400020ANKRD12chr189182517+ENST00000341928EPB41L3chr185489160-479244917603361533
ENST00000400020ANKRD12chr189182517+ENST00000540638EPB41L3chr185489160-341744910511887278

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000383440ENST00000341928ANKRD12chr189182517+EPB41L3chr185489160-0.0014855050.9985145
ENST00000383440ENST00000540638ANKRD12chr189182517+EPB41L3chr185489160-0.0037657950.99623424
ENST00000262126ENST00000341928ANKRD12chr189182517+EPB41L3chr185489160-0.0014432680.9985567
ENST00000262126ENST00000540638ANKRD12chr189182517+EPB41L3chr185489160-0.0037245920.9962754
ENST00000400020ENST00000341928ANKRD12chr189182517+EPB41L3chr185489160-0.0010277060.9989723
ENST00000400020ENST00000540638ANKRD12chr189182517+EPB41L3chr185489160-0.0032132220.99678683

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Fusion Genomic Features for ANKRD12-EPB41L3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ANKRD12-EPB41L3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:9182517/chr18:5489160)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneEPB41L3chr18:9182517chr18:5489160ENST00000341928023110_39101317.3333333333333DomainFERM
TgeneEPB41L3chr18:9182517chr18:5489160ENST00000342933022110_39101088.0DomainFERM
TgeneEPB41L3chr18:9182517chr18:5489160ENST00000400111019110_3910866.0DomainFERM
TgeneEPB41L3chr18:9182517chr18:5489160ENST00000540638020110_3910846.0DomainFERM
TgeneEPB41L3chr18:9182517chr18:5489160ENST00000341928023394_51301317.3333333333333RegionNote=Hydrophilic
TgeneEPB41L3chr18:9182517chr18:5489160ENST00000341928023514_86001317.3333333333333RegionSpectrin--actin-binding
TgeneEPB41L3chr18:9182517chr18:5489160ENST00000341928023861_108301317.3333333333333RegionNote=C-terminal (CTD)
TgeneEPB41L3chr18:9182517chr18:5489160ENST00000342933022394_51301088.0RegionNote=Hydrophilic
TgeneEPB41L3chr18:9182517chr18:5489160ENST00000342933022514_86001088.0RegionSpectrin--actin-binding
TgeneEPB41L3chr18:9182517chr18:5489160ENST00000342933022861_108301088.0RegionNote=C-terminal (CTD)
TgeneEPB41L3chr18:9182517chr18:5489160ENST00000400111019394_5130866.0RegionNote=Hydrophilic
TgeneEPB41L3chr18:9182517chr18:5489160ENST00000400111019514_8600866.0RegionSpectrin--actin-binding
TgeneEPB41L3chr18:9182517chr18:5489160ENST00000400111019861_10830866.0RegionNote=C-terminal (CTD)
TgeneEPB41L3chr18:9182517chr18:5489160ENST00000540638020394_5130846.0RegionNote=Hydrophilic
TgeneEPB41L3chr18:9182517chr18:5489160ENST00000540638020514_8600846.0RegionSpectrin--actin-binding
TgeneEPB41L3chr18:9182517chr18:5489160ENST00000540638020861_10830846.0RegionNote=C-terminal (CTD)

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANKRD12chr18:9182517chr18:5489160ENST00000262126+213184_213292063.0RepeatNote=ANK 1
HgeneANKRD12chr18:9182517chr18:5489160ENST00000262126+213217_246292063.0RepeatNote=ANK 2
HgeneANKRD12chr18:9182517chr18:5489160ENST00000262126+213250_280292063.0RepeatNote=ANK 3
HgeneANKRD12chr18:9182517chr18:5489160ENST00000383440+212184_213292040.0RepeatNote=ANK 1
HgeneANKRD12chr18:9182517chr18:5489160ENST00000383440+212217_246292040.0RepeatNote=ANK 2
HgeneANKRD12chr18:9182517chr18:5489160ENST00000383440+212250_280292040.0RepeatNote=ANK 3
HgeneANKRD12chr18:9182517chr18:5489160ENST00000400020+212184_213292040.0RepeatNote=ANK 1
HgeneANKRD12chr18:9182517chr18:5489160ENST00000400020+212217_246292040.0RepeatNote=ANK 2
HgeneANKRD12chr18:9182517chr18:5489160ENST00000400020+212250_280292040.0RepeatNote=ANK 3


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Fusion Gene Sequence for ANKRD12-EPB41L3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>4574_4574_1_ANKRD12-EPB41L3_ANKRD12_chr18_9182517_ENST00000262126_EPB41L3_chr18_5489160_ENST00000341928_length(transcript)=4670nt_BP=327nt
AATCGCGGGGCGACGCTGTCCTGGGAGCGAGGAGGCTGTGGTGAGAGACGGACCGAGACCGGAGATGTTTTCAAGCCCGGCTCCGGCGGC
TTTACAGGCGGCTGCAGCGGCGACGAAGACAACGACAGCGACGGCTACGCCGAAGCACTCGTTCCGGGGGTGAAGCCTCCTGCGCCGGCC
TTGCCTCGGATCCAGGATGAGAAGACTGATAAAAGAAGAAGCTAGCTGAACAGCTGTAAAATGCCCAAATCTGGGTTCACAAAACCAATT
CAGAGTGAAAATTCTGACAGTGACAGCAATATGGTAGAGAAACCATATGGAAGAAAGGAATAACTTAGCTTGCACATGAATGCAGTCATG
CAAACCGTTAGGAAAACCAGAGCCTATATGGAGTTCCCTCTTCTAACCCAACTGACTTGTATCTGTCCGTGGAAAATTTCAGTCCAGAAG
AATTGACCTTGACCATTAATAAAGACACTGGCAGAGAGATCTTCCCATAATAAAGCAATCTGATTCAGCATCACTAAACCGATAATGCAT
GAAGCAACGATAAAATTACAAAAGAGCAGCATTTTTAATTTTCACAAAATGTCTCAGTTTTCAGCTATACCTGCACGTTCATAACCAACA
ATATAAACCGTGGTCTCATGTAACACATAAACAATTCATGCCTTTCATAGTTTATTATTATTAAAGTCTAAACAAAATTGCAATTTCTTA
GGTAACCTTATATTTACAATAAATGAAGATTACCCTCAAATGCTAGAAGCTGTCTAGGTCCGTCCGGTGTGTCAGATTTTCCTCAGATTA
GATGTGCCAATAACCAAGTTTATTCAGTAAACAACTTGTACTTGTTTCATCTGGTTTTATTACTCTCACCCATAAACAGTAATGACTCTC
TGACCCTCTGGAAATATGTAATGCTTCCAATCTTGCTTTGTGTATCTCATTTAATTTGTTATAAGGTAGTACTGATTTTAGCATATTAAT
GCGATTTCTTCCTTGTTGTTTGCTTTGGTCTGTGTTCAATCCAGAGAGCTTAAATTGTCATTATTTTGGGAAGAAAACCTGTATTTTTGT
TAGTTTACAATATTATGAAATTTCACTTCAGGAGAAACTGCTGGGCTTCCTGTGGCTTTGTTTTCTTAGTTACTTTTTCCGTGCCGTGTA
TTTTTTAATTGATTTTTCTTCTTTTACTTGAAAAGAAAGTGTTTTATTTTCAAATCTGGTCCATATTTACATTCTAGTTCAGAGCCAAGC
CTTAAACTGTACAGAATTTCCACTGTAATTAAAACTATTTAGTGTTAGTTATAAATAGCCTTCAAAAAGAGAGATTCTCCATTACACGAT
CACCTGCATCACAGCCCATGGTGAATGTATGTTTCTGCATAGCGAAATAAAAATGGCAAATGCACTGAAAGCGCGCTGGCTCAGGCAATT
AAAGAGGCCAAAGAGCAGCACCCTGACATGTCAGTGACCAAAGTAGTGGTCCATAAAGAGACAGAGATCACACCAGAAGATGGAGAGGAT
TGACCAGAGACTGTGAAAGGGGGCATTTCAGAGACAAGAATTGAGAAGCGAATAGTCATCACGGGGGATGCAGACATTGACCATGACCAG
GTCGATCCAGGCACAGATCTGGAGCCAGGCGTGCTGATGAGTGCACAGACGATCACATCTGAAACCACCAGTACCACCACCACTACGCAC
ATCACCAAATCCTCAACGGTGAAGACGGAAACCATCAGTTTTGGCAGTGTTTCACCGGGAGGAGTAAAGCTAGAAATTTCCACGAAGGAA
GTGCCAGTAGTTCACACCGAAACCAAAACCATCACATATGAATCATCACAGAAAATGGAAACCAAGACGGAGTCCAGTGGAATAGAGACG
GAACCCACCGTGCACCACCTGCCGCTTAGCACTGAGAAGGTGGTGCAGGAGACCGTGTTGGTGGAGGAGCGGCGTGTGGTGCACGCGAGT
GGGGATGCTTCTTACTCGGCGGGAGACAGCGGGGATGCTGCAGCACAGCCCGCATTCACAGGCATTAAAGGGAAAGAGGGCTCTGCCTTG
ACGGAGGGGGCTAAAGAGGAAGGAGGGGAGGAGGTCGCTAAAGCTGTCCTGGAACAGGAAGAGACAGCCGCTGCTTCCCGTGAGCGACAA
GAGGAGCAGAGTGCAGCCATCCACATTTCAGAAACTTTGGAACAAAAACCTCATTTTGAGACTAAGCAGTCTTCTGGGGAAAAGCTCATG
GATGGCTCTGAAATCTTCAGTTTATTAGAGTCTGCGCGAAAACCAACAGAATTCATAGGAGGGGTTACTTCTACTTCTCAAAGCTGGGTT
CAGGAGCTAGAAAAAACTCAAGATGACCTGATGAAACATCAAACCAACATTAGCGAGCTGAAAAGAACCTTCTTAGAAACCTCAACAGAC
ACTGCCGTAACGAATGAATGGGAGAAGAGGCTTTCCACCTCCCCCGTGCGACTGGCCGCCAGGCAGGAGGATGCCCCCATGATCGAACCA
CTTGTCCCTGAAGAGTCGGACCAGGAGGAAGATGCAGAGCTCAAGGCACAGACTGACAGTGAGCGCACGGACACCGCAGCCGACGGGGAG
ACCACTGCCACTGAGTCACCTGGGCTTGGCACTGACTCATGTCCCTTGTCACCCCCATCCACCCATTGTGCCCCCACATCTCCCACAGAG
CTCCGTAGGAGGTGTAAGGAGAATGACTGCAAACTGCCAGGTTATGAGCCGTCCAGAGCTGAGCACCTGCCTGGAGAGCCCGCCTTGGAC
TCTGATGGCCCAGGGAGGCCTTACCTAGGGGATCAAGATGTGGCTTTTAGCTACAGACAGCAAACTGGCAAGGGGACCACCCTGTTCTCC
TTCTCCTTGCAGCTCCCTGAGTCATTCCCCTCCCTCCTAGATGATGATGGATACCTCTCTTTCCCCAACCTTTCTGAAACCAACCTCCTG
CCCCAGAGCTTGCAGCATTACCTCCCGATCCGCTCACCGTCCCTTGTGCCCTGTTTCCTCTTCATCTTTTTCTTTCTGCTGTCTGCCTCC
TTCTCAGTGCCATACGCTCTCACTCTCTCCTTCCCTCTGGCTCTGTGCCTCTGCTACCTGGAGCCCAAGGCGGCCTCCTTGAGCGCCTCC
CTAGACAATGACCCGAGTGACAGTTCAGAGGAAGAGAGGTTGGTACTGGCCAGTACGCCACAACAAAAGGCATCTCTCAGACCAACTTGA
TCACCACTGTGACTCCGGAGAAGAAGGCTGAGGAGGAGCGGGACGAGGAAGAGGACAAACGGAGGAAGGGGGAAGAAGTCACGCCCATCT
CGGCCATCCGGCACGAGGGAAAGACTACTGTTACCAGAAGCACCTCCCAAGAAATTCCTAACCTTGGGTTCCAAGTTTCGTTATAGTGGC
AGGACACAAGCGCAAACGAGAAGAGCCAGTGCGTTGATAGATCGCCCAGCACCTTACTTTGAACGCTCATCCAGCAAACGTTATACCATG
TCTCGCAGCTTGGATGGAGTTTGAACAATTTGAAAGCACCATTGGGTTTAAGCTGCCAAACCATCGAGCTGCCAAGCGTTTATGGAAAGT
ATGTGTTGAGCATCATACATTTTTCAGGACTCAGAAGGGGTAGAAATTATGTTAGGAGTTTGTGCAAGTGGTCTGTTGATATATCGCGAC
CGGCTGCGAATAAACAGATTTGCCTGGCCCAAGGTTCTAAAGATTTCATACAAACGGAACAACTTTTACATTAAGATCCGGCCGGGAGAG
AGGAATGACGCCAGCAGAAGCAGAGATGCATTTCTTGGAAAATGCCAAAAAATTATCAATGTATGGGGTAGATTTACATCATGCTAAGGT
ACTACCTCTGCTTGCAGTTGCGAGATGACATCGTGTCCGGAAGGCTGCCCTGCTCCTTTGTTACCCTGGCCTTGCTGGGCTCCTACACTG
TCCAGTCAGAGCTCGGAGACTATGACCCAGATGAATGTGGGAGCGATTACATTAGTGAGTTCCGCTTTGCACCAAACCACACTAAAGAAC
TGGAAGACAAAGTGATCGAGCTGCACAAGAGCCACAGGTGGTGCTTGGCACTTTTCATTTAATGTGAAATTTTATCCACCAGACCCTGCC
CAACTATCTGAAGATATCACCAGAATTGGTTGGACCCTGCTAAGGAAATAAAAAAACAGGTTCGAAAAACGCTCCAGAGGACAAGTGCTG
TTTGATAAAGTGTGTGAACACTTGAACTTGCTAGAGAAAGACTACTTTGGGCTTACGTATCGAGATGCTGAAAACCAGAAGGTCACTGAC
AAGGAACAGGAGTTTGCTGCCAGGGCTGCAAAACAGCTCGAATATCAGCAATTAGAAGACGATAAACTTTCTCAGAAATCATCTAGCAGT
AAACTCTCTCGGTCTCCATTAAAGATTGTCAAAAAGCCTAAAAGCATGCAGTGCAAAGTGATACTTCTCGATGGATCAGAATATACCTGT
GATGTAGAGACTCGGAATCCAAGCCGGACCAGGAGGCCGAGCCCCAGGAGGCGGCGGGGGCGCAGGGGCGCGCGGGGGCGCCCGTGCCGG

>4574_4574_1_ANKRD12-EPB41L3_ANKRD12_chr18_9182517_ENST00000262126_EPB41L3_chr18_5489160_ENST00000341928_length(amino acids)=533AA_BP=
MEPGVLMSAQTITSETTSTTTTTHITKSSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQKMETKTESSGIETEPTVHH
LPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAA
IHISETLEQKPHFETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNE
WEKRLSTSPVRLAARQEDAPMIEPLVPEESDQEEDAELKAQTDSERTDTAADGETTATESPGLGTDSCPLSPPSTHCAPTSPTELRRRCK
ENDCKLPGYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKGTTLFSFSLQLPESFPSLLDDDGYLSFPNLSETNLLPQSLQH

--------------------------------------------------------------
>4574_4574_2_ANKRD12-EPB41L3_ANKRD12_chr18_9182517_ENST00000262126_EPB41L3_chr18_5489160_ENST00000540638_length(transcript)=3295nt_BP=327nt
AATCGCGGGGCGACGCTGTCCTGGGAGCGAGGAGGCTGTGGTGAGAGACGGACCGAGACCGGAGATGTTTTCAAGCCCGGCTCCGGCGGC
TTTACAGGCGGCTGCAGCGGCGACGAAGACAACGACAGCGACGGCTACGCCGAAGCACTCGTTCCGGGGGTGAAGCCTCCTGCGCCGGCC
TTGCCTCGGATCCAGGATGAGAAGACTGATAAAAGAAGAAGCTAGCTGAACAGCTGTAAAATGCCCAAATCTGGGTTCACAAAACCAATT
CAGAGTGAAAATTCTGACAGTGACAGCAATATGGTAGAGAAACCATATGGAAGAAAGGAATAACTTAGCTTGCACATGAATGCAGTCATG
CAAACCGTTAGGAAAACCAGAGCCTATATGGAGTTCCCTCTTCTAACCCAACTGACTTGTATCTGTCCGTGGAAAATTTCAGTCCAGAAG
AATTGACCTTGACCATTAATAAAGACACTGGCAGAGAGATCTTCCCATAATAAAGCAATCTGATTCAGCATCACTAAACCGATAATGCAT
GAAGCAACGATAAAATTACAAAAGAGCAGCATTTTTAATTTTCACAAAATGTCTCAGTTTTCAGCTATACCTGCACGTTCATAACCAACA
ATATAAACCGTGGTCTCATGTAACACATAAACAATTCATGCCTTTCATAGTTTATTATTATTAAAGTCTAAACAAAATTGCAAGCGCTGG
CTCAGGCAATTAAAGAGGCCAAAGAGCAGCACCCTGACATGTCAGTGACCAAAGTAGTGGTCCATAAAGAGACAGAGATCACACCAGAAG
ATGGAGAGGATTGACCAGAGACTGTGAAAGGGGGCATTTCAGAGACAAGAATTGAGAAGCGAATAGTCATCACGGGGGATGCAGACATTG
ACCATGACCAGGTCGATCCAGGCACAGATCTGGAGCCAGGCGTGCTGATGAGTGCACAGACGATCACATCTGAAACCACCAGTACCACCA
CCACTACGCACATCACCAAATCCTCAACGGTGAAGACGGAAACCATCAGTTTTGGCAGTGTTTCACCGGGAGGAGTAAAGCTAGAAATTT
CCACGAAGGAAGTGCCAGTAGTTCACACCGAAACCAAAACCATCACATATGAATCATCACAGAAAATGGAAACCAAGACGGAGTCCAGTG
GAATAGAGACGGAACCCACCGTGCACCACCTGCCGCTTAGCACTGAGAAGGTGGTGCAGGAGACCGTGTTGGTGGAGGAGCGGCGTGTGG
TGCACGCGAGTGGGGATGCTTCTTACTCGGCGGGAGACAGCGGGGATGCTGCAGCACAGCCCGCATTCACAGGCATTAAAGGGAAAGAGG
GCTCTGCCTTGACGGAGGGGGCTAAAGAGGAAGGAGGGGAGGAGGTCGCTAAAGCTGTCCTGGAACAGGAAGAGACAGCCGCTGCTTCCC
GTGAGCGACAAGAGGAGCAGAGTGCAGCCATCCACATTTCAGAAACTTTGGAACAAAAACCTCATTTTGAGGAGCTAGAAAAAACTCAAG
ATGACCTGATGAAACATCAAACCAACATTAGCGAGCTGAAAAGAACCTTCTTAGAAACCTCAACAGACACTGCCGTAACGAATGAATGGG
AGAAGAGGCTTTCCACCTCCCCCGTGCGACTGGCCGCCAGGCAGGAGGATGCCCCCATGATCGAACCACTTGTCCCTGAAGAGACTGACA
GTGAGCGCACGGACACCGCAGCCGACGGGGAGACCACTGCCACTGAGCATCAGTGAATGAAAACCATGAAATATACATGAAGGATTCTAT
GTCTGCTGCAGAGGTTGGTACTGGCCAGTACGCCACAACAAAAGGCATCTCTCAGACCAACTTGATCACCACTGTGACTCCGGAGAAGAA
GGCTGAGGAGGAGCGGGACGAGGAAGAGGACAAACGGAGGAAGGGGGAAGAAGTCACGCCCATCTCGGCCATCCGGCACGAGGGAAAGAC
TACTGTTACCAGAAGCACCTCCCAAGAAATTCCTAACCTTGGGTTCCAAGTTTCGTTATAGTGGCAGGACACAAGCGCAAACGAGAAGAG
CCAGTGCGTTGATAGATCGCCCAGCACCTTACTTTGAACGCTCATCCAGCAAACGTTATACCATGTCTCGCAGCTTGGATGGAGTTTGAA
CAATTTGAAAGCACCATTGGGTTTAAGCTGCCAAACCATCGAGCTGCCAAGCGTTTATGGAAAGTATGTGTTGAGCATCATACATTTTTC
AGGACTCAGAAGGGGTAGAAATTATGTTAGGAGTTTGTGCAAGTGGTCTGTTGATATATCGCGACCGGCTGCGAATAAACAGATTTGCCT
GGCCCAAGGTTCTAAAGATTTCATACAAACGGAACAACTTTTACATTAAGATCCGGCCGGGAGAGAGGAATGACGCCAGCAGAAGCAGAG
ATGCATTTCTTGGAAAATGCCAAAAAATTATCAATGTATGGGGTAGATTTACATCATGCTAAGGTACTACCTCTGCTTGCAGTTGCGAGA
TGACATCGTGTCCGGAAGGCTGCCCTGCTCCTTTGTTACCCTGGCCTTGCTGGGCTCCTACACTGTCCAGTCAGAGCTCGGAGACTATGA
CCCAGATGAATGTGGGAGCGATTACATTAGTGAGTTCCGCTTTGCACCAAACCACACTAAAGAACTGGAAGACAAAGTGATCGAGCTGCA
CAAGAGCCACAGGTGGTGCTTGGCACTTTTCATTTAATGTGAAATTTTATCCACCAGACCCTGCCCAACTATCTGAAGATATCACCAGAA
TTGGTTGGACCCTGCTAAGGAAATAAAAAAACAGGTTCGAAAAACGCTCCAGAGGACAAGTGCTGTTTGATAAAGTGTGTGAACACTTGA
ACTTGCTAGAGAAAGACTACTTTGGGCTTACGTATCGAGATGCTGAAAACCAGAAGGTCACTGACAAGGAACAGGAGTTTGCTGCCAGGG
CTGCAAAACAGCTCGAATATCAGCAATTAGAAGACGATAAACTTTCTCAGAAATCATCTAGCAGTAAACTCTCTCGGTCTCCATTAAAGA
TTGTCAAAAAGCCTAAAAGCATGCAGTGCAAAGTGATACTTCTCGATGGATCAGAATATACCTGTGATGTAGAGACTCGGAATCCAAGCC
GGACCAGGAGGCCGAGCCCCAGGAGGCGGCGGGGGCGCAGGGGCGCGCGGGGGCGCCCGTGCCGGAGCCGCCCAAGGAGGAGCAGCAGCA

>4574_4574_2_ANKRD12-EPB41L3_ANKRD12_chr18_9182517_ENST00000262126_EPB41L3_chr18_5489160_ENST00000540638_length(amino acids)=278AA_BP=
MEPGVLMSAQTITSETTSTTTTTHITKSSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQKMETKTESSGIETEPTVHH
LPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAA
IHISETLEQKPHFEELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLVPEETDSERTDTAADG

--------------------------------------------------------------
>4574_4574_3_ANKRD12-EPB41L3_ANKRD12_chr18_9182517_ENST00000383440_EPB41L3_chr18_5489160_ENST00000341928_length(transcript)=4687nt_BP=344nt
GTGCTCGCGTCGCAGCCAATCGCGGGGCGACGCTGTCCTGGGAGCGAGGAGGCTGTGGTGAGAGACGGACCGAGACCGGAGATGTTTTCA
AGCCCGGCTCCGGCGGCTTTACAGGCGGCTGCAGCGGCGACGAAGACAACGACAGCGACGGCTACGCCGAAGCACTCGTTCCGGGGGTGA
AGCCTCCTGCGCCGGCCTTGCCTCGGATCCAGGATGAGAAGACTGATAAAAGAAGAAGCTAGCTGAACAGCTGTAAAATGCCCAAATCTG
GGTTCACAAAACCAATTCAGAGTGAAAATTCTGACAGTGACAGCAATATGGTAGAGAAACCATATGGAAGAAAGGAATAACTTAGCTTGC
ACATGAATGCAGTCATGCAAACCGTTAGGAAAACCAGAGCCTATATGGAGTTCCCTCTTCTAACCCAACTGACTTGTATCTGTCCGTGGA
AAATTTCAGTCCAGAAGAATTGACCTTGACCATTAATAAAGACACTGGCAGAGAGATCTTCCCATAATAAAGCAATCTGATTCAGCATCA
CTAAACCGATAATGCATGAAGCAACGATAAAATTACAAAAGAGCAGCATTTTTAATTTTCACAAAATGTCTCAGTTTTCAGCTATACCTG
CACGTTCATAACCAACAATATAAACCGTGGTCTCATGTAACACATAAACAATTCATGCCTTTCATAGTTTATTATTATTAAAGTCTAAAC
AAAATTGCAATTTCTTAGGTAACCTTATATTTACAATAAATGAAGATTACCCTCAAATGCTAGAAGCTGTCTAGGTCCGTCCGGTGTGTC
AGATTTTCCTCAGATTAGATGTGCCAATAACCAAGTTTATTCAGTAAACAACTTGTACTTGTTTCATCTGGTTTTATTACTCTCACCCAT
AAACAGTAATGACTCTCTGACCCTCTGGAAATATGTAATGCTTCCAATCTTGCTTTGTGTATCTCATTTAATTTGTTATAAGGTAGTACT
GATTTTAGCATATTAATGCGATTTCTTCCTTGTTGTTTGCTTTGGTCTGTGTTCAATCCAGAGAGCTTAAATTGTCATTATTTTGGGAAG
AAAACCTGTATTTTTGTTAGTTTACAATATTATGAAATTTCACTTCAGGAGAAACTGCTGGGCTTCCTGTGGCTTTGTTTTCTTAGTTAC
TTTTTCCGTGCCGTGTATTTTTTAATTGATTTTTCTTCTTTTACTTGAAAAGAAAGTGTTTTATTTTCAAATCTGGTCCATATTTACATT
CTAGTTCAGAGCCAAGCCTTAAACTGTACAGAATTTCCACTGTAATTAAAACTATTTAGTGTTAGTTATAAATAGCCTTCAAAAAGAGAG
ATTCTCCATTACACGATCACCTGCATCACAGCCCATGGTGAATGTATGTTTCTGCATAGCGAAATAAAAATGGCAAATGCACTGAAAGCG
CGCTGGCTCAGGCAATTAAAGAGGCCAAAGAGCAGCACCCTGACATGTCAGTGACCAAAGTAGTGGTCCATAAAGAGACAGAGATCACAC
CAGAAGATGGAGAGGATTGACCAGAGACTGTGAAAGGGGGCATTTCAGAGACAAGAATTGAGAAGCGAATAGTCATCACGGGGGATGCAG
ACATTGACCATGACCAGGTCGATCCAGGCACAGATCTGGAGCCAGGCGTGCTGATGAGTGCACAGACGATCACATCTGAAACCACCAGTA
CCACCACCACTACGCACATCACCAAATCCTCAACGGTGAAGACGGAAACCATCAGTTTTGGCAGTGTTTCACCGGGAGGAGTAAAGCTAG
AAATTTCCACGAAGGAAGTGCCAGTAGTTCACACCGAAACCAAAACCATCACATATGAATCATCACAGAAAATGGAAACCAAGACGGAGT
CCAGTGGAATAGAGACGGAACCCACCGTGCACCACCTGCCGCTTAGCACTGAGAAGGTGGTGCAGGAGACCGTGTTGGTGGAGGAGCGGC
GTGTGGTGCACGCGAGTGGGGATGCTTCTTACTCGGCGGGAGACAGCGGGGATGCTGCAGCACAGCCCGCATTCACAGGCATTAAAGGGA
AAGAGGGCTCTGCCTTGACGGAGGGGGCTAAAGAGGAAGGAGGGGAGGAGGTCGCTAAAGCTGTCCTGGAACAGGAAGAGACAGCCGCTG
CTTCCCGTGAGCGACAAGAGGAGCAGAGTGCAGCCATCCACATTTCAGAAACTTTGGAACAAAAACCTCATTTTGAGACTAAGCAGTCTT
CTGGGGAAAAGCTCATGGATGGCTCTGAAATCTTCAGTTTATTAGAGTCTGCGCGAAAACCAACAGAATTCATAGGAGGGGTTACTTCTA
CTTCTCAAAGCTGGGTTCAGGAGCTAGAAAAAACTCAAGATGACCTGATGAAACATCAAACCAACATTAGCGAGCTGAAAAGAACCTTCT
TAGAAACCTCAACAGACACTGCCGTAACGAATGAATGGGAGAAGAGGCTTTCCACCTCCCCCGTGCGACTGGCCGCCAGGCAGGAGGATG
CCCCCATGATCGAACCACTTGTCCCTGAAGAGTCGGACCAGGAGGAAGATGCAGAGCTCAAGGCACAGACTGACAGTGAGCGCACGGACA
CCGCAGCCGACGGGGAGACCACTGCCACTGAGTCACCTGGGCTTGGCACTGACTCATGTCCCTTGTCACCCCCATCCACCCATTGTGCCC
CCACATCTCCCACAGAGCTCCGTAGGAGGTGTAAGGAGAATGACTGCAAACTGCCAGGTTATGAGCCGTCCAGAGCTGAGCACCTGCCTG
GAGAGCCCGCCTTGGACTCTGATGGCCCAGGGAGGCCTTACCTAGGGGATCAAGATGTGGCTTTTAGCTACAGACAGCAAACTGGCAAGG
GGACCACCCTGTTCTCCTTCTCCTTGCAGCTCCCTGAGTCATTCCCCTCCCTCCTAGATGATGATGGATACCTCTCTTTCCCCAACCTTT
CTGAAACCAACCTCCTGCCCCAGAGCTTGCAGCATTACCTCCCGATCCGCTCACCGTCCCTTGTGCCCTGTTTCCTCTTCATCTTTTTCT
TTCTGCTGTCTGCCTCCTTCTCAGTGCCATACGCTCTCACTCTCTCCTTCCCTCTGGCTCTGTGCCTCTGCTACCTGGAGCCCAAGGCGG
CCTCCTTGAGCGCCTCCCTAGACAATGACCCGAGTGACAGTTCAGAGGAAGAGAGGTTGGTACTGGCCAGTACGCCACAACAAAAGGCAT
CTCTCAGACCAACTTGATCACCACTGTGACTCCGGAGAAGAAGGCTGAGGAGGAGCGGGACGAGGAAGAGGACAAACGGAGGAAGGGGGA
AGAAGTCACGCCCATCTCGGCCATCCGGCACGAGGGAAAGACTACTGTTACCAGAAGCACCTCCCAAGAAATTCCTAACCTTGGGTTCCA
AGTTTCGTTATAGTGGCAGGACACAAGCGCAAACGAGAAGAGCCAGTGCGTTGATAGATCGCCCAGCACCTTACTTTGAACGCTCATCCA
GCAAACGTTATACCATGTCTCGCAGCTTGGATGGAGTTTGAACAATTTGAAAGCACCATTGGGTTTAAGCTGCCAAACCATCGAGCTGCC
AAGCGTTTATGGAAAGTATGTGTTGAGCATCATACATTTTTCAGGACTCAGAAGGGGTAGAAATTATGTTAGGAGTTTGTGCAAGTGGTC
TGTTGATATATCGCGACCGGCTGCGAATAAACAGATTTGCCTGGCCCAAGGTTCTAAAGATTTCATACAAACGGAACAACTTTTACATTA
AGATCCGGCCGGGAGAGAGGAATGACGCCAGCAGAAGCAGAGATGCATTTCTTGGAAAATGCCAAAAAATTATCAATGTATGGGGTAGAT
TTACATCATGCTAAGGTACTACCTCTGCTTGCAGTTGCGAGATGACATCGTGTCCGGAAGGCTGCCCTGCTCCTTTGTTACCCTGGCCTT
GCTGGGCTCCTACACTGTCCAGTCAGAGCTCGGAGACTATGACCCAGATGAATGTGGGAGCGATTACATTAGTGAGTTCCGCTTTGCACC
AAACCACACTAAAGAACTGGAAGACAAAGTGATCGAGCTGCACAAGAGCCACAGGTGGTGCTTGGCACTTTTCATTTAATGTGAAATTTT
ATCCACCAGACCCTGCCCAACTATCTGAAGATATCACCAGAATTGGTTGGACCCTGCTAAGGAAATAAAAAAACAGGTTCGAAAAACGCT
CCAGAGGACAAGTGCTGTTTGATAAAGTGTGTGAACACTTGAACTTGCTAGAGAAAGACTACTTTGGGCTTACGTATCGAGATGCTGAAA
ACCAGAAGGTCACTGACAAGGAACAGGAGTTTGCTGCCAGGGCTGCAAAACAGCTCGAATATCAGCAATTAGAAGACGATAAACTTTCTC
AGAAATCATCTAGCAGTAAACTCTCTCGGTCTCCATTAAAGATTGTCAAAAAGCCTAAAAGCATGCAGTGCAAAGTGATACTTCTCGATG
GATCAGAATATACCTGTGATGTAGAGACTCGGAATCCAAGCCGGACCAGGAGGCCGAGCCCCAGGAGGCGGCGGGGGCGCAGGGGCGCGC
GGGGGCGCCCGTGCCGGAGCCGCCCAAGGAGGAGCAGCAGCAGGCCCTGGAGCAGTTCGCCGCCGCTGCAGCGCACAGCACCCCGGTGCG

>4574_4574_3_ANKRD12-EPB41L3_ANKRD12_chr18_9182517_ENST00000383440_EPB41L3_chr18_5489160_ENST00000341928_length(amino acids)=533AA_BP=
MEPGVLMSAQTITSETTSTTTTTHITKSSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQKMETKTESSGIETEPTVHH
LPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAA
IHISETLEQKPHFETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNE
WEKRLSTSPVRLAARQEDAPMIEPLVPEESDQEEDAELKAQTDSERTDTAADGETTATESPGLGTDSCPLSPPSTHCAPTSPTELRRRCK
ENDCKLPGYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKGTTLFSFSLQLPESFPSLLDDDGYLSFPNLSETNLLPQSLQH

--------------------------------------------------------------
>4574_4574_4_ANKRD12-EPB41L3_ANKRD12_chr18_9182517_ENST00000383440_EPB41L3_chr18_5489160_ENST00000540638_length(transcript)=3312nt_BP=344nt
GTGCTCGCGTCGCAGCCAATCGCGGGGCGACGCTGTCCTGGGAGCGAGGAGGCTGTGGTGAGAGACGGACCGAGACCGGAGATGTTTTCA
AGCCCGGCTCCGGCGGCTTTACAGGCGGCTGCAGCGGCGACGAAGACAACGACAGCGACGGCTACGCCGAAGCACTCGTTCCGGGGGTGA
AGCCTCCTGCGCCGGCCTTGCCTCGGATCCAGGATGAGAAGACTGATAAAAGAAGAAGCTAGCTGAACAGCTGTAAAATGCCCAAATCTG
GGTTCACAAAACCAATTCAGAGTGAAAATTCTGACAGTGACAGCAATATGGTAGAGAAACCATATGGAAGAAAGGAATAACTTAGCTTGC
ACATGAATGCAGTCATGCAAACCGTTAGGAAAACCAGAGCCTATATGGAGTTCCCTCTTCTAACCCAACTGACTTGTATCTGTCCGTGGA
AAATTTCAGTCCAGAAGAATTGACCTTGACCATTAATAAAGACACTGGCAGAGAGATCTTCCCATAATAAAGCAATCTGATTCAGCATCA
CTAAACCGATAATGCATGAAGCAACGATAAAATTACAAAAGAGCAGCATTTTTAATTTTCACAAAATGTCTCAGTTTTCAGCTATACCTG
CACGTTCATAACCAACAATATAAACCGTGGTCTCATGTAACACATAAACAATTCATGCCTTTCATAGTTTATTATTATTAAAGTCTAAAC
AAAATTGCAAGCGCTGGCTCAGGCAATTAAAGAGGCCAAAGAGCAGCACCCTGACATGTCAGTGACCAAAGTAGTGGTCCATAAAGAGAC
AGAGATCACACCAGAAGATGGAGAGGATTGACCAGAGACTGTGAAAGGGGGCATTTCAGAGACAAGAATTGAGAAGCGAATAGTCATCAC
GGGGGATGCAGACATTGACCATGACCAGGTCGATCCAGGCACAGATCTGGAGCCAGGCGTGCTGATGAGTGCACAGACGATCACATCTGA
AACCACCAGTACCACCACCACTACGCACATCACCAAATCCTCAACGGTGAAGACGGAAACCATCAGTTTTGGCAGTGTTTCACCGGGAGG
AGTAAAGCTAGAAATTTCCACGAAGGAAGTGCCAGTAGTTCACACCGAAACCAAAACCATCACATATGAATCATCACAGAAAATGGAAAC
CAAGACGGAGTCCAGTGGAATAGAGACGGAACCCACCGTGCACCACCTGCCGCTTAGCACTGAGAAGGTGGTGCAGGAGACCGTGTTGGT
GGAGGAGCGGCGTGTGGTGCACGCGAGTGGGGATGCTTCTTACTCGGCGGGAGACAGCGGGGATGCTGCAGCACAGCCCGCATTCACAGG
CATTAAAGGGAAAGAGGGCTCTGCCTTGACGGAGGGGGCTAAAGAGGAAGGAGGGGAGGAGGTCGCTAAAGCTGTCCTGGAACAGGAAGA
GACAGCCGCTGCTTCCCGTGAGCGACAAGAGGAGCAGAGTGCAGCCATCCACATTTCAGAAACTTTGGAACAAAAACCTCATTTTGAGGA
GCTAGAAAAAACTCAAGATGACCTGATGAAACATCAAACCAACATTAGCGAGCTGAAAAGAACCTTCTTAGAAACCTCAACAGACACTGC
CGTAACGAATGAATGGGAGAAGAGGCTTTCCACCTCCCCCGTGCGACTGGCCGCCAGGCAGGAGGATGCCCCCATGATCGAACCACTTGT
CCCTGAAGAGACTGACAGTGAGCGCACGGACACCGCAGCCGACGGGGAGACCACTGCCACTGAGCATCAGTGAATGAAAACCATGAAATA
TACATGAAGGATTCTATGTCTGCTGCAGAGGTTGGTACTGGCCAGTACGCCACAACAAAAGGCATCTCTCAGACCAACTTGATCACCACT
GTGACTCCGGAGAAGAAGGCTGAGGAGGAGCGGGACGAGGAAGAGGACAAACGGAGGAAGGGGGAAGAAGTCACGCCCATCTCGGCCATC
CGGCACGAGGGAAAGACTACTGTTACCAGAAGCACCTCCCAAGAAATTCCTAACCTTGGGTTCCAAGTTTCGTTATAGTGGCAGGACACA
AGCGCAAACGAGAAGAGCCAGTGCGTTGATAGATCGCCCAGCACCTTACTTTGAACGCTCATCCAGCAAACGTTATACCATGTCTCGCAG
CTTGGATGGAGTTTGAACAATTTGAAAGCACCATTGGGTTTAAGCTGCCAAACCATCGAGCTGCCAAGCGTTTATGGAAAGTATGTGTTG
AGCATCATACATTTTTCAGGACTCAGAAGGGGTAGAAATTATGTTAGGAGTTTGTGCAAGTGGTCTGTTGATATATCGCGACCGGCTGCG
AATAAACAGATTTGCCTGGCCCAAGGTTCTAAAGATTTCATACAAACGGAACAACTTTTACATTAAGATCCGGCCGGGAGAGAGGAATGA
CGCCAGCAGAAGCAGAGATGCATTTCTTGGAAAATGCCAAAAAATTATCAATGTATGGGGTAGATTTACATCATGCTAAGGTACTACCTC
TGCTTGCAGTTGCGAGATGACATCGTGTCCGGAAGGCTGCCCTGCTCCTTTGTTACCCTGGCCTTGCTGGGCTCCTACACTGTCCAGTCA
GAGCTCGGAGACTATGACCCAGATGAATGTGGGAGCGATTACATTAGTGAGTTCCGCTTTGCACCAAACCACACTAAAGAACTGGAAGAC
AAAGTGATCGAGCTGCACAAGAGCCACAGGTGGTGCTTGGCACTTTTCATTTAATGTGAAATTTTATCCACCAGACCCTGCCCAACTATC
TGAAGATATCACCAGAATTGGTTGGACCCTGCTAAGGAAATAAAAAAACAGGTTCGAAAAACGCTCCAGAGGACAAGTGCTGTTTGATAA
AGTGTGTGAACACTTGAACTTGCTAGAGAAAGACTACTTTGGGCTTACGTATCGAGATGCTGAAAACCAGAAGGTCACTGACAAGGAACA
GGAGTTTGCTGCCAGGGCTGCAAAACAGCTCGAATATCAGCAATTAGAAGACGATAAACTTTCTCAGAAATCATCTAGCAGTAAACTCTC
TCGGTCTCCATTAAAGATTGTCAAAAAGCCTAAAAGCATGCAGTGCAAAGTGATACTTCTCGATGGATCAGAATATACCTGTGATGTAGA
GACTCGGAATCCAAGCCGGACCAGGAGGCCGAGCCCCAGGAGGCGGCGGGGGCGCAGGGGCGCGCGGGGGCGCCCGTGCCGGAGCCGCCC

>4574_4574_4_ANKRD12-EPB41L3_ANKRD12_chr18_9182517_ENST00000383440_EPB41L3_chr18_5489160_ENST00000540638_length(amino acids)=278AA_BP=
MEPGVLMSAQTITSETTSTTTTTHITKSSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQKMETKTESSGIETEPTVHH
LPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAA
IHISETLEQKPHFEELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLVPEETDSERTDTAADG

--------------------------------------------------------------
>4574_4574_5_ANKRD12-EPB41L3_ANKRD12_chr18_9182517_ENST00000400020_EPB41L3_chr18_5489160_ENST00000341928_length(transcript)=4792nt_BP=449nt
CGGCCGCTCGGGCCGGGAGCGTCGGAGGTACCCGGGTCCTGGGAGAGGTGGATGAAATCAAGAAGGGGAAATTGCTGCTTTAGTAGTGTC
CGGGGAAAGAGCAGCCACTCTACAGTTCTGTCTTAAATGCCAGTGTAAAATAACCTTGCCGCATTGGACAGGCAGTTCCCGTCATCGTTT
TTCAAGTACCCACTTGTGATGCTTCAAGACCCCTGGAGCACGTCAGGTTCTTAGATCTCGTTTTGAGGAGTGATGTGGAGTGACGCATCC
TTACAGATCCCAAAGCGTTGAATAAACGGTTGTACAAAGAGATCCAGGATGAGAAGACTGATAAAAGAAGAAGCTAGCTGAACAGCTGTA
AAATGCCCAAATCTGGGTTCACAAAACCAATTCAGAGTGAAAATTCTGACAGTGACAGCAATATGGTAGAGAAACCATATGGAAGAAAGG
AATAACTTAGCTTGCACATGAATGCAGTCATGCAAACCGTTAGGAAAACCAGAGCCTATATGGAGTTCCCTCTTCTAACCCAACTGACTT
GTATCTGTCCGTGGAAAATTTCAGTCCAGAAGAATTGACCTTGACCATTAATAAAGACACTGGCAGAGAGATCTTCCCATAATAAAGCAA
TCTGATTCAGCATCACTAAACCGATAATGCATGAAGCAACGATAAAATTACAAAAGAGCAGCATTTTTAATTTTCACAAAATGTCTCAGT
TTTCAGCTATACCTGCACGTTCATAACCAACAATATAAACCGTGGTCTCATGTAACACATAAACAATTCATGCCTTTCATAGTTTATTAT
TATTAAAGTCTAAACAAAATTGCAATTTCTTAGGTAACCTTATATTTACAATAAATGAAGATTACCCTCAAATGCTAGAAGCTGTCTAGG
TCCGTCCGGTGTGTCAGATTTTCCTCAGATTAGATGTGCCAATAACCAAGTTTATTCAGTAAACAACTTGTACTTGTTTCATCTGGTTTT
ATTACTCTCACCCATAAACAGTAATGACTCTCTGACCCTCTGGAAATATGTAATGCTTCCAATCTTGCTTTGTGTATCTCATTTAATTTG
TTATAAGGTAGTACTGATTTTAGCATATTAATGCGATTTCTTCCTTGTTGTTTGCTTTGGTCTGTGTTCAATCCAGAGAGCTTAAATTGT
CATTATTTTGGGAAGAAAACCTGTATTTTTGTTAGTTTACAATATTATGAAATTTCACTTCAGGAGAAACTGCTGGGCTTCCTGTGGCTT
TGTTTTCTTAGTTACTTTTTCCGTGCCGTGTATTTTTTAATTGATTTTTCTTCTTTTACTTGAAAAGAAAGTGTTTTATTTTCAAATCTG
GTCCATATTTACATTCTAGTTCAGAGCCAAGCCTTAAACTGTACAGAATTTCCACTGTAATTAAAACTATTTAGTGTTAGTTATAAATAG
CCTTCAAAAAGAGAGATTCTCCATTACACGATCACCTGCATCACAGCCCATGGTGAATGTATGTTTCTGCATAGCGAAATAAAAATGGCA
AATGCACTGAAAGCGCGCTGGCTCAGGCAATTAAAGAGGCCAAAGAGCAGCACCCTGACATGTCAGTGACCAAAGTAGTGGTCCATAAAG
AGACAGAGATCACACCAGAAGATGGAGAGGATTGACCAGAGACTGTGAAAGGGGGCATTTCAGAGACAAGAATTGAGAAGCGAATAGTCA
TCACGGGGGATGCAGACATTGACCATGACCAGGTCGATCCAGGCACAGATCTGGAGCCAGGCGTGCTGATGAGTGCACAGACGATCACAT
CTGAAACCACCAGTACCACCACCACTACGCACATCACCAAATCCTCAACGGTGAAGACGGAAACCATCAGTTTTGGCAGTGTTTCACCGG
GAGGAGTAAAGCTAGAAATTTCCACGAAGGAAGTGCCAGTAGTTCACACCGAAACCAAAACCATCACATATGAATCATCACAGAAAATGG
AAACCAAGACGGAGTCCAGTGGAATAGAGACGGAACCCACCGTGCACCACCTGCCGCTTAGCACTGAGAAGGTGGTGCAGGAGACCGTGT
TGGTGGAGGAGCGGCGTGTGGTGCACGCGAGTGGGGATGCTTCTTACTCGGCGGGAGACAGCGGGGATGCTGCAGCACAGCCCGCATTCA
CAGGCATTAAAGGGAAAGAGGGCTCTGCCTTGACGGAGGGGGCTAAAGAGGAAGGAGGGGAGGAGGTCGCTAAAGCTGTCCTGGAACAGG
AAGAGACAGCCGCTGCTTCCCGTGAGCGACAAGAGGAGCAGAGTGCAGCCATCCACATTTCAGAAACTTTGGAACAAAAACCTCATTTTG
AGACTAAGCAGTCTTCTGGGGAAAAGCTCATGGATGGCTCTGAAATCTTCAGTTTATTAGAGTCTGCGCGAAAACCAACAGAATTCATAG
GAGGGGTTACTTCTACTTCTCAAAGCTGGGTTCAGGAGCTAGAAAAAACTCAAGATGACCTGATGAAACATCAAACCAACATTAGCGAGC
TGAAAAGAACCTTCTTAGAAACCTCAACAGACACTGCCGTAACGAATGAATGGGAGAAGAGGCTTTCCACCTCCCCCGTGCGACTGGCCG
CCAGGCAGGAGGATGCCCCCATGATCGAACCACTTGTCCCTGAAGAGTCGGACCAGGAGGAAGATGCAGAGCTCAAGGCACAGACTGACA
GTGAGCGCACGGACACCGCAGCCGACGGGGAGACCACTGCCACTGAGTCACCTGGGCTTGGCACTGACTCATGTCCCTTGTCACCCCCAT
CCACCCATTGTGCCCCCACATCTCCCACAGAGCTCCGTAGGAGGTGTAAGGAGAATGACTGCAAACTGCCAGGTTATGAGCCGTCCAGAG
CTGAGCACCTGCCTGGAGAGCCCGCCTTGGACTCTGATGGCCCAGGGAGGCCTTACCTAGGGGATCAAGATGTGGCTTTTAGCTACAGAC
AGCAAACTGGCAAGGGGACCACCCTGTTCTCCTTCTCCTTGCAGCTCCCTGAGTCATTCCCCTCCCTCCTAGATGATGATGGATACCTCT
CTTTCCCCAACCTTTCTGAAACCAACCTCCTGCCCCAGAGCTTGCAGCATTACCTCCCGATCCGCTCACCGTCCCTTGTGCCCTGTTTCC
TCTTCATCTTTTTCTTTCTGCTGTCTGCCTCCTTCTCAGTGCCATACGCTCTCACTCTCTCCTTCCCTCTGGCTCTGTGCCTCTGCTACC
TGGAGCCCAAGGCGGCCTCCTTGAGCGCCTCCCTAGACAATGACCCGAGTGACAGTTCAGAGGAAGAGAGGTTGGTACTGGCCAGTACGC
CACAACAAAAGGCATCTCTCAGACCAACTTGATCACCACTGTGACTCCGGAGAAGAAGGCTGAGGAGGAGCGGGACGAGGAAGAGGACAA
ACGGAGGAAGGGGGAAGAAGTCACGCCCATCTCGGCCATCCGGCACGAGGGAAAGACTACTGTTACCAGAAGCACCTCCCAAGAAATTCC
TAACCTTGGGTTCCAAGTTTCGTTATAGTGGCAGGACACAAGCGCAAACGAGAAGAGCCAGTGCGTTGATAGATCGCCCAGCACCTTACT
TTGAACGCTCATCCAGCAAACGTTATACCATGTCTCGCAGCTTGGATGGAGTTTGAACAATTTGAAAGCACCATTGGGTTTAAGCTGCCA
AACCATCGAGCTGCCAAGCGTTTATGGAAAGTATGTGTTGAGCATCATACATTTTTCAGGACTCAGAAGGGGTAGAAATTATGTTAGGAG
TTTGTGCAAGTGGTCTGTTGATATATCGCGACCGGCTGCGAATAAACAGATTTGCCTGGCCCAAGGTTCTAAAGATTTCATACAAACGGA
ACAACTTTTACATTAAGATCCGGCCGGGAGAGAGGAATGACGCCAGCAGAAGCAGAGATGCATTTCTTGGAAAATGCCAAAAAATTATCA
ATGTATGGGGTAGATTTACATCATGCTAAGGTACTACCTCTGCTTGCAGTTGCGAGATGACATCGTGTCCGGAAGGCTGCCCTGCTCCTT
TGTTACCCTGGCCTTGCTGGGCTCCTACACTGTCCAGTCAGAGCTCGGAGACTATGACCCAGATGAATGTGGGAGCGATTACATTAGTGA
GTTCCGCTTTGCACCAAACCACACTAAAGAACTGGAAGACAAAGTGATCGAGCTGCACAAGAGCCACAGGTGGTGCTTGGCACTTTTCAT
TTAATGTGAAATTTTATCCACCAGACCCTGCCCAACTATCTGAAGATATCACCAGAATTGGTTGGACCCTGCTAAGGAAATAAAAAAACA
GGTTCGAAAAACGCTCCAGAGGACAAGTGCTGTTTGATAAAGTGTGTGAACACTTGAACTTGCTAGAGAAAGACTACTTTGGGCTTACGT
ATCGAGATGCTGAAAACCAGAAGGTCACTGACAAGGAACAGGAGTTTGCTGCCAGGGCTGCAAAACAGCTCGAATATCAGCAATTAGAAG
ACGATAAACTTTCTCAGAAATCATCTAGCAGTAAACTCTCTCGGTCTCCATTAAAGATTGTCAAAAAGCCTAAAAGCATGCAGTGCAAAG
TGATACTTCTCGATGGATCAGAATATACCTGTGATGTAGAGACTCGGAATCCAAGCCGGACCAGGAGGCCGAGCCCCAGGAGGCGGCGGG
GGCGCAGGGGCGCGCGGGGGCGCCCGTGCCGGAGCCGCCCAAGGAGGAGCAGCAGCAGGCCCTGGAGCAGTTCGCCGCCGCTGCAGCGCA

>4574_4574_5_ANKRD12-EPB41L3_ANKRD12_chr18_9182517_ENST00000400020_EPB41L3_chr18_5489160_ENST00000341928_length(amino acids)=533AA_BP=
MEPGVLMSAQTITSETTSTTTTTHITKSSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQKMETKTESSGIETEPTVHH
LPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAA
IHISETLEQKPHFETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNE
WEKRLSTSPVRLAARQEDAPMIEPLVPEESDQEEDAELKAQTDSERTDTAADGETTATESPGLGTDSCPLSPPSTHCAPTSPTELRRRCK
ENDCKLPGYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKGTTLFSFSLQLPESFPSLLDDDGYLSFPNLSETNLLPQSLQH

--------------------------------------------------------------
>4574_4574_6_ANKRD12-EPB41L3_ANKRD12_chr18_9182517_ENST00000400020_EPB41L3_chr18_5489160_ENST00000540638_length(transcript)=3417nt_BP=449nt
CGGCCGCTCGGGCCGGGAGCGTCGGAGGTACCCGGGTCCTGGGAGAGGTGGATGAAATCAAGAAGGGGAAATTGCTGCTTTAGTAGTGTC
CGGGGAAAGAGCAGCCACTCTACAGTTCTGTCTTAAATGCCAGTGTAAAATAACCTTGCCGCATTGGACAGGCAGTTCCCGTCATCGTTT
TTCAAGTACCCACTTGTGATGCTTCAAGACCCCTGGAGCACGTCAGGTTCTTAGATCTCGTTTTGAGGAGTGATGTGGAGTGACGCATCC
TTACAGATCCCAAAGCGTTGAATAAACGGTTGTACAAAGAGATCCAGGATGAGAAGACTGATAAAAGAAGAAGCTAGCTGAACAGCTGTA
AAATGCCCAAATCTGGGTTCACAAAACCAATTCAGAGTGAAAATTCTGACAGTGACAGCAATATGGTAGAGAAACCATATGGAAGAAAGG
AATAACTTAGCTTGCACATGAATGCAGTCATGCAAACCGTTAGGAAAACCAGAGCCTATATGGAGTTCCCTCTTCTAACCCAACTGACTT
GTATCTGTCCGTGGAAAATTTCAGTCCAGAAGAATTGACCTTGACCATTAATAAAGACACTGGCAGAGAGATCTTCCCATAATAAAGCAA
TCTGATTCAGCATCACTAAACCGATAATGCATGAAGCAACGATAAAATTACAAAAGAGCAGCATTTTTAATTTTCACAAAATGTCTCAGT
TTTCAGCTATACCTGCACGTTCATAACCAACAATATAAACCGTGGTCTCATGTAACACATAAACAATTCATGCCTTTCATAGTTTATTAT
TATTAAAGTCTAAACAAAATTGCAAGCGCTGGCTCAGGCAATTAAAGAGGCCAAAGAGCAGCACCCTGACATGTCAGTGACCAAAGTAGT
GGTCCATAAAGAGACAGAGATCACACCAGAAGATGGAGAGGATTGACCAGAGACTGTGAAAGGGGGCATTTCAGAGACAAGAATTGAGAA
GCGAATAGTCATCACGGGGGATGCAGACATTGACCATGACCAGGTCGATCCAGGCACAGATCTGGAGCCAGGCGTGCTGATGAGTGCACA
GACGATCACATCTGAAACCACCAGTACCACCACCACTACGCACATCACCAAATCCTCAACGGTGAAGACGGAAACCATCAGTTTTGGCAG
TGTTTCACCGGGAGGAGTAAAGCTAGAAATTTCCACGAAGGAAGTGCCAGTAGTTCACACCGAAACCAAAACCATCACATATGAATCATC
ACAGAAAATGGAAACCAAGACGGAGTCCAGTGGAATAGAGACGGAACCCACCGTGCACCACCTGCCGCTTAGCACTGAGAAGGTGGTGCA
GGAGACCGTGTTGGTGGAGGAGCGGCGTGTGGTGCACGCGAGTGGGGATGCTTCTTACTCGGCGGGAGACAGCGGGGATGCTGCAGCACA
GCCCGCATTCACAGGCATTAAAGGGAAAGAGGGCTCTGCCTTGACGGAGGGGGCTAAAGAGGAAGGAGGGGAGGAGGTCGCTAAAGCTGT
CCTGGAACAGGAAGAGACAGCCGCTGCTTCCCGTGAGCGACAAGAGGAGCAGAGTGCAGCCATCCACATTTCAGAAACTTTGGAACAAAA
ACCTCATTTTGAGGAGCTAGAAAAAACTCAAGATGACCTGATGAAACATCAAACCAACATTAGCGAGCTGAAAAGAACCTTCTTAGAAAC
CTCAACAGACACTGCCGTAACGAATGAATGGGAGAAGAGGCTTTCCACCTCCCCCGTGCGACTGGCCGCCAGGCAGGAGGATGCCCCCAT
GATCGAACCACTTGTCCCTGAAGAGACTGACAGTGAGCGCACGGACACCGCAGCCGACGGGGAGACCACTGCCACTGAGCATCAGTGAAT
GAAAACCATGAAATATACATGAAGGATTCTATGTCTGCTGCAGAGGTTGGTACTGGCCAGTACGCCACAACAAAAGGCATCTCTCAGACC
AACTTGATCACCACTGTGACTCCGGAGAAGAAGGCTGAGGAGGAGCGGGACGAGGAAGAGGACAAACGGAGGAAGGGGGAAGAAGTCACG
CCCATCTCGGCCATCCGGCACGAGGGAAAGACTACTGTTACCAGAAGCACCTCCCAAGAAATTCCTAACCTTGGGTTCCAAGTTTCGTTA
TAGTGGCAGGACACAAGCGCAAACGAGAAGAGCCAGTGCGTTGATAGATCGCCCAGCACCTTACTTTGAACGCTCATCCAGCAAACGTTA
TACCATGTCTCGCAGCTTGGATGGAGTTTGAACAATTTGAAAGCACCATTGGGTTTAAGCTGCCAAACCATCGAGCTGCCAAGCGTTTAT
GGAAAGTATGTGTTGAGCATCATACATTTTTCAGGACTCAGAAGGGGTAGAAATTATGTTAGGAGTTTGTGCAAGTGGTCTGTTGATATA
TCGCGACCGGCTGCGAATAAACAGATTTGCCTGGCCCAAGGTTCTAAAGATTTCATACAAACGGAACAACTTTTACATTAAGATCCGGCC
GGGAGAGAGGAATGACGCCAGCAGAAGCAGAGATGCATTTCTTGGAAAATGCCAAAAAATTATCAATGTATGGGGTAGATTTACATCATG
CTAAGGTACTACCTCTGCTTGCAGTTGCGAGATGACATCGTGTCCGGAAGGCTGCCCTGCTCCTTTGTTACCCTGGCCTTGCTGGGCTCC
TACACTGTCCAGTCAGAGCTCGGAGACTATGACCCAGATGAATGTGGGAGCGATTACATTAGTGAGTTCCGCTTTGCACCAAACCACACT
AAAGAACTGGAAGACAAAGTGATCGAGCTGCACAAGAGCCACAGGTGGTGCTTGGCACTTTTCATTTAATGTGAAATTTTATCCACCAGA
CCCTGCCCAACTATCTGAAGATATCACCAGAATTGGTTGGACCCTGCTAAGGAAATAAAAAAACAGGTTCGAAAAACGCTCCAGAGGACA
AGTGCTGTTTGATAAAGTGTGTGAACACTTGAACTTGCTAGAGAAAGACTACTTTGGGCTTACGTATCGAGATGCTGAAAACCAGAAGGT
CACTGACAAGGAACAGGAGTTTGCTGCCAGGGCTGCAAAACAGCTCGAATATCAGCAATTAGAAGACGATAAACTTTCTCAGAAATCATC
TAGCAGTAAACTCTCTCGGTCTCCATTAAAGATTGTCAAAAAGCCTAAAAGCATGCAGTGCAAAGTGATACTTCTCGATGGATCAGAATA
TACCTGTGATGTAGAGACTCGGAATCCAAGCCGGACCAGGAGGCCGAGCCCCAGGAGGCGGCGGGGGCGCAGGGGCGCGCGGGGGCGCCC

>4574_4574_6_ANKRD12-EPB41L3_ANKRD12_chr18_9182517_ENST00000400020_EPB41L3_chr18_5489160_ENST00000540638_length(amino acids)=278AA_BP=
MEPGVLMSAQTITSETTSTTTTTHITKSSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQKMETKTESSGIETEPTVHH
LPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAA
IHISETLEQKPHFEELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLVPEETDSERTDTAADG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ANKRD12-EPB41L3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ANKRD12-EPB41L3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ANKRD12-EPB41L3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0006142Malignant neoplasm of breast1CTD_human
TgeneC0678222Breast Carcinoma1CTD_human
TgeneC1257931Mammary Neoplasms, Human1CTD_human
TgeneC1458155Mammary Neoplasms1CTD_human
TgeneC4704874Mammary Carcinoma, Human1CTD_human