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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:CLEC16A-SNTB2 (FusionGDB2 ID:HG23274TG6645) |
Fusion Gene Summary for CLEC16A-SNTB2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CLEC16A-SNTB2 | Fusion gene ID: hg23274tg6645 | Hgene | Tgene | Gene symbol | CLEC16A | SNTB2 | Gene ID | 23274 | 6645 |
| Gene name | C-type lectin domain containing 16A | syntrophin beta 2 | |
| Synonyms | Gop-1|KIAA0350 | D16S2531E|EST25263|SNT2B2|SNT3|SNTL | |
| Cytomap | ('CLEC16A')('SNTB2') 16p13.13 | 16q22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein CLEC16AC-type lectin domain family 16 member A | beta-2-syntrophin59 kDa dystrophin-associated protein A1 basic component 2dystrophin-associated protein A1, 59kD, basic component 2syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)syntrophin-3 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000409552, ENST00000409790, ENST00000381822, ENST00000465491, | ||
| Fusion gene scores | * DoF score | 13 X 9 X 9=1053 | 18 X 15 X 13=3510 |
| # samples | 16 | 24 | |
| ** MAII score | log2(16/1053*10)=-2.71836162613835 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(24/3510*10)=-3.8703647195834 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CLEC16A [Title/Abstract] AND SNTB2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | CLEC16A(11076848)-SNTB2(69304046), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | CLEC16A-SNTB2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CLEC16A-SNTB2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CLEC16A-SNTB2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CLEC16A-SNTB2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across CLEC16A (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across SNTB2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | Non-Cancer | ERR188416 | CLEC16A | chr16 | 11076848 | + | SNTB2 | chr16 | 69304046 | + |
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Fusion Gene ORF analysis for CLEC16A-SNTB2 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-3UTR | ENST00000409552 | ENST00000528525 | CLEC16A | chr16 | 11076848 | + | SNTB2 | chr16 | 69304046 | + |
| 5CDS-3UTR | ENST00000409790 | ENST00000528525 | CLEC16A | chr16 | 11076848 | + | SNTB2 | chr16 | 69304046 | + |
| In-frame | ENST00000409552 | ENST00000336278 | CLEC16A | chr16 | 11076848 | + | SNTB2 | chr16 | 69304046 | + |
| In-frame | ENST00000409790 | ENST00000336278 | CLEC16A | chr16 | 11076848 | + | SNTB2 | chr16 | 69304046 | + |
| intron-3CDS | ENST00000381822 | ENST00000336278 | CLEC16A | chr16 | 11076848 | + | SNTB2 | chr16 | 69304046 | + |
| intron-3CDS | ENST00000465491 | ENST00000336278 | CLEC16A | chr16 | 11076848 | + | SNTB2 | chr16 | 69304046 | + |
| intron-3UTR | ENST00000381822 | ENST00000528525 | CLEC16A | chr16 | 11076848 | + | SNTB2 | chr16 | 69304046 | + |
| intron-3UTR | ENST00000465491 | ENST00000528525 | CLEC16A | chr16 | 11076848 | + | SNTB2 | chr16 | 69304046 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000409790 | CLEC16A | chr16 | 11076848 | + | ENST00000336278 | SNTB2 | chr16 | 69304046 | + | 10047 | 1301 | 230 | 1918 | 562 |
| ENST00000409552 | CLEC16A | chr16 | 11076848 | + | ENST00000336278 | SNTB2 | chr16 | 69304046 | + | 9948 | 1202 | 137 | 1819 | 560 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000409790 | ENST00000336278 | CLEC16A | chr16 | 11076848 | + | SNTB2 | chr16 | 69304046 | + | 0.000268734 | 0.99973124 |
| ENST00000409552 | ENST00000336278 | CLEC16A | chr16 | 11076848 | + | SNTB2 | chr16 | 69304046 | + | 0.000285171 | 0.9997148 |
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Fusion Genomic Features for CLEC16A-SNTB2 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| CLEC16A | chr16 | 11076848 | + | SNTB2 | chr16 | 69304045 | + | 1.02E-05 | 0.99998975 |
| CLEC16A | chr16 | 11076848 | + | SNTB2 | chr16 | 69304045 | + | 1.02E-05 | 0.99998975 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for CLEC16A-SNTB2 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:11076848/chr16:69304046) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CLEC16A | chr16:11076848 | chr16:69304046 | ENST00000409552 | + | 9 | 21 | 51_198 | 355 | 907.0 | Domain | FPL |
| Hgene | CLEC16A | chr16:11076848 | chr16:69304046 | ENST00000409790 | + | 10 | 24 | 51_198 | 357 | 1054.0 | Domain | FPL |
| Tgene | SNTB2 | chr16:11076848 | chr16:69304046 | ENST00000336278 | 2 | 7 | 484_540 | 335 | 541.0 | Domain | Note=SU | |
| Tgene | SNTB2 | chr16:11076848 | chr16:69304046 | ENST00000336278 | 2 | 7 | 518_540 | 335 | 541.0 | Region | Calmodulin-binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CLEC16A | chr16:11076848 | chr16:69304046 | ENST00000381822 | + | 1 | 4 | 892_933 | 0 | 141.0 | Compositional bias | Note=Ser-rich |
| Hgene | CLEC16A | chr16:11076848 | chr16:69304046 | ENST00000409552 | + | 9 | 21 | 892_933 | 355 | 907.0 | Compositional bias | Note=Ser-rich |
| Hgene | CLEC16A | chr16:11076848 | chr16:69304046 | ENST00000409790 | + | 10 | 24 | 892_933 | 357 | 1054.0 | Compositional bias | Note=Ser-rich |
| Hgene | CLEC16A | chr16:11076848 | chr16:69304046 | ENST00000381822 | + | 1 | 4 | 51_198 | 0 | 141.0 | Domain | FPL |
| Tgene | SNTB2 | chr16:11076848 | chr16:69304046 | ENST00000336278 | 2 | 7 | 54_57 | 335 | 541.0 | Compositional bias | Note=Poly-Ala | |
| Tgene | SNTB2 | chr16:11076848 | chr16:69304046 | ENST00000336278 | 2 | 7 | 66_69 | 335 | 541.0 | Compositional bias | Note=Poly-Ala | |
| Tgene | SNTB2 | chr16:11076848 | chr16:69304046 | ENST00000336278 | 2 | 7 | 115_198 | 335 | 541.0 | Domain | PDZ | |
| Tgene | SNTB2 | chr16:11076848 | chr16:69304046 | ENST00000336278 | 2 | 7 | 163_300 | 335 | 541.0 | Domain | PH 1 | |
| Tgene | SNTB2 | chr16:11076848 | chr16:69304046 | ENST00000336278 | 2 | 7 | 325_437 | 335 | 541.0 | Domain | PH 2 |
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Fusion Gene Sequence for CLEC16A-SNTB2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >17085_17085_1_CLEC16A-SNTB2_CLEC16A_chr16_11076848_ENST00000409552_SNTB2_chr16_69304046_ENST00000336278_length(transcript)=9948nt_BP=1202nt CGGGGAGGAAGGCGGCTCGCGGTTCCTCCACCGCCTCCGCCGCCGCATCCTCCGCTTGTGCTACCGCCGCGGGCGCTGGGCCGCTCTGCT GGTCCGGCATGAGACCGTGAGACGAGAGACGGGTCGGGGCCGCCGACATGTTTGGCCGCTCGCGGAGCTGGGTGGGCGGGGGCCATGGCA AGACTTCCCGCAACATCCACTCCTTGGACCACCTCAAGTATCTGTACCACGTTTTGACCAAAAACACCACAGTCACAGAACAGAACCGGA ACCTGCTAGTGGAGACCATCCGTTCCATCACTGAGATCCTGATCTGGGGAGATCAAAATGACAGCTCTGTATTTGACTTCTTCCTGGAGA AGAATATGTTTGTTTTCTTCTTGAACATCTTGCGGCAAAAGTCGGGCCGTTACGTGTGCGTTCAGCTGCTGCAGACCTTGAACATCCTCT TTGAGAACATCAGTCACGAGACCTCACTTTATTATTTGCTCTCAAATAACTACGTAAATTCTATCATCGTTCATAAATTTGACTTTTCTG ATGAGGAGATTATGGCCTATTATATATCGTTCCTGAAAACACTTTCGTTAAAACTCAACAACCACACTGTCCATTTCTTTTATAATGAGC ACACCAATGACTTTGCCCTGTACACAGAAGCCATCAAGTTTTTCAACCACCCTGAAAGCATGGTTAGAATTGCTGTAAGAACCATAACTT TGAATGTCTATAAAGTGGATAACCAGGCCATGCTGCACTACATCCGAGATAAAACTGCTGTTCCTTACTTCTCCAATTTGGTCTGGTTCA TTGGGAGCCATGTGATCGAACTCGATGACTGCGTGCAGACTGATGAGGAGCATCGGAATCGGGGTAAACTGAGTGATCTGGTGGCAGAGC ACCTAGACCACCTGCACTATCTCAATGACATCCTGATCATCAACTGTGAGTTCCTCAACGATGTGCTCACTGACCACCTGCTCAACAGGC TCTTCCTGCCCCTCTACGTGTACTCACTGGAGAACCAGGACAAGGGAGGAGAACGGCCGAAAATTAGCCTGCCGGTGTCTCTTTATCTTC TGTCACAGGTCTTCTTAATTATACATCATGCACCGCTGGTGAACTCGTTAGCTGAAGTCATTCTGAATGGTGATCTGTCTGAGATGTACG CTAAGACTGAACAGGATATTCAGAGAAGTTCTGCAAAACTAGATGGTGGAAGACAGCAATGGAGACCTGTCCTCATGGCTGTGACTGAGA AGGATTTGCTGCTCTATGACTGTATGCCGTGGACAAGAGATGCCTGGGCGTCACCATGCCACAGCTACCCACTTGTTGCCACCAGGTTGG TTCATTCTGGCTCCGGATGTCGATCCCCCTCCCTTGGATCTGACCTTACATTTGCTACCAGGACAGGCTCTCGACAGGGCATTGAGATGC ATCTCTTCAGGGTGGAGACACATCGGGATCTGTCATCCTGGACCAGGATACTTGTTCAGGGTTGCCATGCTGCTGCTGAGCTGATCAAGG AAGTCTCTCTAGGCTGCATGTTAAATGGCCAAGAGGTGAGGCTTACTATTCACTATGAAAATGGGTTCACCATCTCAAGGGAAAATGGAG GCTCCAGCAGCATATTGTACCGCTACCCCTTTGAAAGGCTGAAGATGTCTGCTGATGATGGCATCCGAAATCTATACTTGGATTTTGGTG GTCCCGAGGGAGAACTGACCATGGACCTGCACTCTTGTCCGAAGCCGATTGTATTTGTGTTGCACACGTTTTTATCGGCCAAAGTCACTC GTATGGGACTGCTTGTATGAGCAACAAAAAATCAGAAAAGAGCCTTGACTGTCACAAGAAATATTTCCACCTCAAAAAAAAAAAAGCACA AAAAGAAACTCTTTGCTCTCCTTCAGCACAGTGCCTTCCCAAGGACCTGCAAATAACTGCTGAACCATAACCGTGTTTAAAGAAGAGCCT ACCTTTCACAGTCTACCTTGGCCAGATATTCTAGCACTCTAAAAGGCTCCAAAATGAAGCTGTTGATTTATTCTCATTTCAAAATATGGT TTATGAGTAATTAGGTTTATTTCTACTGCTAAAAAGAATGGCTCATTGTTTTCTTTTTTTTTCATTGTTTTCATTTTTAGACATAATCAA ATACCCAAGCATTGTTTTCTTTTTCTTCTCCCTGTAGGATTTGTGTTGTGCTTAGCCTTGATCTCTTGTTCAGAACAATTGTCCCTTCCC AGGTGCTAGCTTGCAGCAGCCTGTTGCTTCCTGAGCATTCCAGATAGGTCGTATGTCTTGGAATTTACTGTCCTCACTAGCTCCTTCCAC CATAGGAAGTCCTTGAATTGTATCACCAAAGGGTTGTTCCATTTGCCCTGGATCTCCCTCTATCTCAGCCTGGCCATCACTTCCCACCTT ATCCCAAGCTTTGCCACTGTCTCTAGGACTTAGAACTTGTAAATTTGATTTGCCTTGCCTTCTACTTCCTTTCTAGTGGTGACTGAGTTG AAAAGCAAGTTGGAAGCCACTGCTTTTAAAGAAAAGTTTTGCTTGGTTTAGGTTTTTCCAATTTTATTTTTGTTAGGAGCCAGGGGATAA GATTTATTTTAAATGAAAATCCTCTTCCTAGGTTAAGCCATTTTTTTTATTGCTTACCAAATGTGCCTTTGGTTAGGGTTAGTGGAGCTT TATTAGTCACTATTTGAATAACTGGAAATCACTGCCATTTCCAGGAGATCACCTATCCTAGTTTTGAGGAATAGTCATTGAGGTGGGTTT CCTTAATGGCATCTCTTCTAGTAGGCAGATCTGTTTGAACAAGATAAATCCTAAAGAGCCAGCCTGCTTGAGGAGTAGACTTGGTGGGTG AAGCCAGCAATTCCGCACAAACGTCATGTTGAATTGTTTTGGGCTGCCCAAAAACAACAGGATGCAGCATCCTGGCTGTGGCCTGGCCCT TTGTGGCAGCAGTGGCATGGACAAGCAACTGCTAATTCGAGACTTACTATTGGCTTCACAGCACACCCTACAGTGAGCAGGGTGATGAGA CCGTGGAACAGCTACCTGCTTTTGGTTAAGATTGCCAGATATCATTAGGACACAGTAGCAGCAAGAATGCTGATTTTGTAGTGTTAGAAA ATGAACTCAGCTTGTTTTTCCTAATTTTGAAGGTGGTATATATCTGCAAACATTTAAAATGGTATAATATCATATAAAATGTCAAAATTA GCACAGTCCCTGGATCTCAAAGAATAGGTAATATTGACTTGGATGTTCTTTATGCTCTCTGAAGAAAGGTCTAGGGAAAGTTCTTGTTTG CTTGATTGATCAAGAGTGCCACGGAAGAATGTGAGCGCTGTGGAGGGTGGAGGAGGGTGTCACTTCAGATGGGGCAGGCACAGGGGGAGA AAAGAAGAGAAAAACACACCTGTGTGCAAAATGAGCTATTTGGTTTCAGTGCGGCCTGACCGATGGGGAGGACCCATGAGCAGAGAGAGT TCTAGGTCAACATTGTAACTCCATTGTCCTCCTTCACCCATAAGTCAGTCCTCCTTCCTCATTACAGTGAAACCAACAATATGCAGAGGT TGGGGAGAGATGCCTGTTCTTCCCCCAGCTTCATATAATTGTCAAAGTTCCAAAAATGAATTATCTGAACTGCTTAAAACTGGAAATTAA AATCTAGACAAGAATATGTCTTTCAAGAGCTTTTTATGTTTTGAAAGTTCATAAACCTAAGATTGGCTCCATCTGAGATAAATTTTCTTT TCTTTTTTTTTTTGAGACGGAGTCTCGTTCTGTCTCCCAGGCTGGAGTGCAGTGGCATGATCTCGGCTCACTGCAACCTCCACCTCCTAG GTTCAAGTGATTCTCCTGAGTAGCTGGGGTTATAGCTACCCACCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGGCAGGTTTTCA CCATGTTGGCTAGGCTGGTCTTGAACTCCCGACCTCAAGTGATCCACCTGCCTTGGCCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCC CCGTGCCTGGCCCACAATAAATTTTCATTTCAGAGAAGGAAAAAAATCTCTTGAACGTCCAGAAATGATTTCTGGAATCAGAATTTCAAT ATGTAATACCCTCAGGTAGGCAATCTTGAACCCTCTATGCAGTGAGAGCATTATTAATATGAGATGTTGAATGATGCCTTTACAGACTTC AGCAGCAAAGCCATTTGGTTGAGGTTTTCTGTGTTAATGTGAAAAGCTAAGCCACTGAGATTTGCAGGGGAGCTTCTGAGCCACCCTGCT TGTTGGTTATATGAGGATGTAAAATAGGTGGAATTAAAATGTGAGCAGGAAAGGCAAGGCATGTGTGCATTTTCACTCATTTTGGTCAAG GTTAAACTGACATGTATAGCACTGAGGTCTGTAGGGTTCTTAATATCTTTTGAGTCTTGCTGTGAAATGAAAGTGTGGGAGGTTTCCTTT GTCCATTAGCAGCCCCAAGAACCAGAACCCTTTTGCTGCTTTTCTTACATACCTAACAGCTCTCCAGTCATGATGACCAAGGTTGTTCTT CAATCAAATGTGTTTGTGGGATTTTCAGTCCGCAAATGAAGTGCTCTCTAATGAATGGGACACCATGATAAATATGTATTTATATTTAGA TGCCAAAGTATGGCAAATTATTTCCAAATGATAACTACAAATGGGAATTTTCGATATTCTACCTTTTTTATAGAACCAGCTCACTTTTCA TTTCTTTTTCATTTTGAATTAAGAAAATTGTTGAGGATGTGGTGGGTTCCAGTGTGTGGAATGGAAAGGAAACTGCAGAATAGTGTCTGC TCCCCATTCAGAGGGACTGCTTCCTGTGCCCCCCAGACCCGGGGCTTCGACAGCTTCTCCACATTCCACACAGATGCCTAGGAGCAGCGA GTTGGTATATGAAAAGTCTCCCACCTTTTCTCCTAAAACTTCTCTCCTTTCTCTCCATAAAAAGAAAAGGAAAGGAACAAAAGAAAAACA TTCAGTTTTTCTTTTTCTGAAAAAGGTAAGTCCTTTCCTGAAGTCATCAAATGAAACATTATCTGGAAATTAGTTTCTAATGTTGTATAT GAAGAAATACTTAAATATAAGTTCCTGCAGTATTTATTAGATAGTTGTAACTGTAAACTCACCTCCCTAGTAGATAAGAGTTTCAGGTTA AATACTGGAACATATATAGGCAGTCAAAAATACTACTTTAAATGTCATTCACCTATTTTAAAGCCATGTTTTAGCACTTTTTAGGCCAAA GAAGGTCTGATAGTGCCTGTTTTTATGTTCTGTACTCTCACAAACTTTGTTACTCAAAATTATTGCATGGCAGGAGAGATTGGATTATTT ATTTCTTATATTTTTATAAGTAAAAAAATCTTTCTAAACAACAAATACCTAACATTATTACTGATTGTTTTCCTAATTTATCCTCCTAAG TTGAATGGTAACAAAGCTTTTCCAGCTGAATGAATGCACTTAGCTGATAAACCAGAATTTGTTCTTTTTTTTCCTTCTTTTTTTTTTGAG ACAGGTTCTCACTCTGTCACCGAGGTTGGAGTGCAGTGGTATGATCATAGCTGACTGCAGCCTCAACCTTCTGGGCTCAAATGATCCTTT CACCTCAGCCTCCTGAGTAGCTGGGACCACAGGTGTGTGCCACCACACCTGGCTAATTTTTATGGATTTTTTTTTCTTTTTTTTTTTTCG CCATGTTGCCCAGGCTGGTCTTGAACTCTTGGCACTCAAGCAGTCCTTCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGATGTGAGCC ACTGCACCTGGCCCCAGAAATTATGCTTAAAAAAAAAATTAAGCTGTGTGGAATCTGGACAAGGCTATGTTTCTCCTAGAAACAGGTTTT GCTGTAAATGGTTTTGATGGGCGAAAGTGTGAGAAAAGGTTATAATAGATTCTTTTTTTTAATTTTGTGAGAAATTCCAGGTCTTCTTGC TTAACTTATATGCATGTGGATATATTTGTTTTCAAAGCCATGGAAGAATCTCTGTTCATATATTTTAATGCAAATTACCTTGTATGCTGC TATGCAAATTCTATTAAAAGGCCTACCTGCTTAAGAATTAAACATTTTTGAAACTTTCAGGGAAGACCTGTAGACTCAAGCACTTTCTCT GCTTTTTTGTATCTTATCTTGGACACTTATGCTGAATTATGTTCTTATTATTTTCACTGGTTATAAGCTATTCCTTGTACATAATATTTA AACTATCCAAATATCCAGCATACATTTCCATGTGGCTGCCATCGGCTGTTGATGCCATGAATGAAATGGCTGGTTAGAAAGCCAAAGGTC TTCTTTTTTCAATTCCTAATGAATAAGTAAAATGCCAGATCTCTTTGGTCTCAAAGCAAATTGCTCTGATCAGATCAAATATCTATGTAA TGAAAAGAGACTTACTTAAATTTGGGATTCTGCTTAAACTTTAAGTTGAATTTGACTGTAGTCATTCATTCTTTTTATATATCTCTGTCA GGTATGACATTAATTACCAGGTGGTATTATACTCTACTTTGAGTTTGGACATCACTTTCAGTTAAATTTCTGTTGTTATTGTGGCTTTTT TTTTTTTTTAACCCCACTGAAGATGGAAGTAGAGCAGTCTGCCATCTCCTGCTGTTCTTTCTCTGTGCCCCCTAATTGCTTGGTAATCTA AAATTATTCTGACTTTCCACATACTGTCTTTAAAAACCAATTGTAGCAATCTGCCCGCCTCCACCCTTTAAGCTAAATCTTTCACTGTGC TGGATACATAGACACTCGATAAATGTGTGATGATAGTTCTAAAATAATTATGCTATATATCAGGGTTCTGTATTTTTGAGCAATATCATT ATTCCTATGCTGTGATGTTAAATGGAATTTATTTTACACTAGTAATAGACTGCTTAAGTGGCTGATTTGAAACCTTTCTCTAAAAAAACA AAAACATCTGGCAGATGAGTGACACAAATTCATTCTCTTAAAGGATAGAATTTCAAGTTAAGGATAAGGCACAATAAATAGGCACATAGA GGACATCTGTTTTTGTTTTTGGTTTTGGTTTTGTTTTTTTTTGTCTCTCTGACTAGCTAAACTGCCAACTAGAAGAATGGTTGTTATGTA GTAACTCAGAAGAATCTTTTAATAAGTTTCTTCTTTTGTTTCAAAACAAACTTGAGCTTCATTTCTTGCCACCTCTATTCTTTCTTCCCA CGTTGGGTGACTGAACTGATGCTTATTCTAGTTTTAGAAGAGGATCCACATTTAATGTAAGGCATAAATATGCCTTTTGCAAATTATTGC TTGTTCTCCAGTGAACATTTGATCATATTCAACAGAAATCCACCATATAAACCATAATCCTTGAATTGCCCCTTTTAAAATAGATTGGTT AAAACCAAAAACCTATAAGAGAGAAATGATATTTCATTGTATTGTAGGTTTGGGAATCCTGGTTAGATTTATAATTTCTGGCCGGGTGCG GTGGCTCATGCCTGTATTCCCAGTACTTTGGGAGCCCAAGGTGGGTGGATCACCTGAGGTAAGGAGTTTGAGACCAGCCTGGCCAACATG GTGAAACCCCATCTCTACTAAAAATACAAAAAGTTAGCTGGGCATGGTGGTGCGCGCCTGTGGTCCCAGCTACTCGGGAGGCTGAGGTGG GAGAATCCCTTGAACCCAGGAGGCAGAAGTTGCAGTGAGCTGAGATCATGCCATTGCACTCCAGCCTGGGCAACAGAGCGAGACTTCATC TCCAAAAAAAGAAAAAGAAGAAAAAGATTTATAATTTCTGAGTCCCCTAAGTCCCTTTCTCAGTTTGCAATAATCTTACGTCCATGCTAT TGACACTAATTTTGAAACTGGAAAGCTAATTAATGACATATTCATGTGTTCTTTCATCTAATAAACATTTATTAATGTATAGTTCTACAC CAGGCATTCTGAAGGGTCCAAAAGAAAGTTCCTGCCCTCTAGTAGCACATAATCCGTTATTTCTCAGCACACCATGCCATCTGTTTATCA TTCAGCAGTTAAGTAATTCATCACTTCATATTTTTACCAAAGTATATTTACAAGTCTGTTTATCTGGATCTGGCAAACTGGAAAATGTTT GAAGGGATACTCAGGCTTTGATCCATGCCAACATGAAAGGACTCCAAGCACATTTAAGTAGGCTGGTCTTTTCATCATGCATGATTTTTT TTTTAGTGCAAATTTAGACTTTAGTTTGGGAAAGAGAACAGTATACAGTATCCTTTGTAAGATAAATCACAACAACAAAAATTAAGTTTT ATTGCACAAAGTAGATAAATGAGAAAGTCTTTCTTAAAAAATGCTTCTTTAACTGTAACAGCAAAACTAAATGCATATTTTATCAACCCC TTATTTCTAATTGCTGTATTCATTTCCACCCTTAAACTATTTAAGCATTTCATCTGCTGAAAGTCCTTATATACATGGTAGACGGAATAT TTCTCCATTAATGATAGATCAAAATGAAGATATTTAAAAATTAACAAAATCAGGCCAAGGCAGGAGGATCACTTTAGCCCAGGAGGTCCA GACCAGCCTGGGCAACACAGCGGGACCCCGACTCCATTTAAAAAATTAAAAAAAAAAAAAAAACTTTTAACATTTAAAAAATAAAAATTA ACAAAATTTCACTTATTCCAGGACACGCTGGCATTTGGACTCAATGAAAAGGGCACCTAAAGAAAATAAGGCTGACTGAATGTTTTCCAT AATTTTCACACAATAACAGTCCCTTTCTATCCAGCTTGCCTTCCATTTATCTCTAGGGTTAGCTTTTCAGGCAACATCCTTGGTCATTGC CCAGAAAGTACCTGAGCTATCAGTGATTGGAATGGCACAGGAAACCGAATCACATGGGTGCCCTCCCCTTGGTTTTCAAGTATCTTGGAG TTGTGCACAAAAATTAGGTCATGCCTTCAGTGTCTTGTTCTTTAAACCTACCCTTTGACAATCAGGTGCTAATGATTGTATACTATTAAA ACCAGCACATAAGTATTGTAAATGTGTGTTCCTCCTAGGTTGGAAGAAATGTCTTTCCTTCTATCTGGGTCCTGTTAAAGCGGGTGTCAG TTGTGTCTTTTCACCTCGATTTGTGAATTAATAGAATTGGGGGGAGAGGAAATGATGATGTCAATTAAGTTTCAGGTTTGGCATGATCAT CATTCTCGATGATATTCTCACTTTGTCGCAAATCTGCCCTTATCGTAAGAACAAGTTTCAGAATTTTCCCTCCACTATACGACTCCAGTA TTATGTTTACAATCCATTGGATGAGTGCAGCATTATAAGACCTTGGTGCCCAGAAAAATCTGTCCTTTTTGGTACCAAACCTGAGGTCTT TTGGAAGATAATGTAGAAAACCACTACCTATTGAAGGCCTGTTTTGGCTAATCTGTGCAAACTCTGATGATACCTGCTTATGTGGATTCT TTTCCACACTGCTTTCATTTTTAAGTATAAAGACTTAGAAAACTAGAATAATGCTTTTACAAATAATTAAAAGTATGTGATGTTCTGGGT TTTTTCCTTCTTTTTAGAACCCTGTATTTAAACAAGCCTTCTTTTTAAGTCTTGTTTGAAATTTAAGTCTCAGATCTTCTGGATACCAAA TCAAAAACCCAACGCGTAAAACAGGGCAGTATTTGTGTTCCTAATTTTAAAAAGCTTTATGTATACTCTATAAATATAGATGCATAAACA ACACTTCCCCTTGAGTAGCACATCAACATACAGCATTGTACATTACAATGAAAATGTGTAACTTAAGGGTATTATATATATAAATACATA TATACCTTTGTAACCTTTATACTGTAAATAAAAAAGTTGCTTTAGTCA >17085_17085_1_CLEC16A-SNTB2_CLEC16A_chr16_11076848_ENST00000409552_SNTB2_chr16_69304046_ENST00000336278_length(amino acids)=560AA_BP=355 MFGRSRSWVGGGHGKTSRNIHSLDHLKYLYHVLTKNTTVTEQNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSG RYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFN HPESMVRIAVRTITLNVYKVDNQAMLHYIRDKTAVPYFSNLVWFIGSHVIELDDCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINC EFLNDVLTDHLLNRLFLPLYVYSLENQDKGGERPKISLPVSLYLLSQVFLIIHHAPLVNSLAEVILNGDLSEMYAKTEQDIQRSSAKLDG GRQQWRPVLMAVTEKDLLLYDCMPWTRDAWASPCHSYPLVATRLVHSGSGCRSPSLGSDLTFATRTGSRQGIEMHLFRVETHRDLSSWTR ILVQGCHAAAELIKEVSLGCMLNGQEVRLTIHYENGFTISRENGGSSSILYRYPFERLKMSADDGIRNLYLDFGGPEGELTMDLHSCPKP IVFVLHTFLSAKVTRMGLLV -------------------------------------------------------------- >17085_17085_2_CLEC16A-SNTB2_CLEC16A_chr16_11076848_ENST00000409790_SNTB2_chr16_69304046_ENST00000336278_length(transcript)=10047nt_BP=1301nt AACTGCATTTCCCAGCGCCCCACGCGGCGGCGGCCGTAAAGCGCGGCGGTCGAACGGCCGGTTCCGGCTGAATGTCAGTGCTGGGCTGTG GGCCGGGGAGGAAGGCGGCTCGCGGTTCCTCCACCGCCTCCGCCGCCGCATCCTCCGCTTGTGCTACCGCCGCGGGCGCTGGGCCGCTCT GCTGGTCCGGCATGAGACCGTGAGACGAGAGACGGGTCGGGGCCGCCGACATGTTTGGCCGCTCGCGGAGCTGGGTGGGCGGGGGCCATG GCAAGACTTCCCGCAACATCCACTCCTTGGACCACCTCAAGTATCTGTACCACGTTTTGACCAAAAACACCACAGTCACAGAACAGAACC GGAACCTGCTAGTGGAGACCATCCGTTCCATCACTGAGATCCTGATCTGGGGAGATCAAAATGACAGCTCTGTATTTGACTTCTTCCTGG AGAAGAATATGTTTGTTTTCTTCTTGAACATCTTGCGGCAAAAGTCGGGCCGTTACGTGTGCGTTCAGCTGCTGCAGACCTTGAACATCC TCTTTGAGAACATCAGTCACGAGACCTCACTTTATTATTTGCTCTCAAATAACTACGTAAATTCTATCATCGTTCATAAATTTGACTTTT CTGATGAGGAGATTATGGCCTATTATATATCGTTCCTGAAAACACTTTCGTTAAAACTCAACAACCACACTGTCCATTTCTTTTATAATG AGCACACCAATGACTTTGCCCTGTACACAGAAGCCATCAAGTTTTTCAACCACCCTGAAAGCATGGTTAGAATTGCTGTAAGAACCATAA CTTTGAATGTCTATAAAGTGTCATTGGATAACCAGGCCATGCTGCACTACATCCGAGATAAAACTGCTGTTCCTTACTTCTCCAATTTGG TCTGGTTCATTGGGAGCCATGTGATCGAACTCGATGACTGCGTGCAGACTGATGAGGAGCATCGGAATCGGGGTAAACTGAGTGATCTGG TGGCAGAGCACCTAGACCACCTGCACTATCTCAATGACATCCTGATCATCAACTGTGAGTTCCTCAACGATGTGCTCACTGACCACCTGC TCAACAGGCTCTTCCTGCCCCTCTACGTGTACTCACTGGAGAACCAGGACAAGGGAGGAGAACGGCCGAAAATTAGCCTGCCGGTGTCTC TTTATCTTCTGTCACAGGTCTTCTTAATTATACATCATGCACCGCTGGTGAACTCGTTAGCTGAAGTCATTCTGAATGGTGATCTGTCTG AGATGTACGCTAAGACTGAACAGGATATTCAGAGAAGTTCTGCAAAACTAGATGGTGGAAGACAGCAATGGAGACCTGTCCTCATGGCTG TGACTGAGAAGGATTTGCTGCTCTATGACTGTATGCCGTGGACAAGAGATGCCTGGGCGTCACCATGCCACAGCTACCCACTTGTTGCCA CCAGGTTGGTTCATTCTGGCTCCGGATGTCGATCCCCCTCCCTTGGATCTGACCTTACATTTGCTACCAGGACAGGCTCTCGACAGGGCA TTGAGATGCATCTCTTCAGGGTGGAGACACATCGGGATCTGTCATCCTGGACCAGGATACTTGTTCAGGGTTGCCATGCTGCTGCTGAGC TGATCAAGGAAGTCTCTCTAGGCTGCATGTTAAATGGCCAAGAGGTGAGGCTTACTATTCACTATGAAAATGGGTTCACCATCTCAAGGG AAAATGGAGGCTCCAGCAGCATATTGTACCGCTACCCCTTTGAAAGGCTGAAGATGTCTGCTGATGATGGCATCCGAAATCTATACTTGG ATTTTGGTGGTCCCGAGGGAGAACTGACCATGGACCTGCACTCTTGTCCGAAGCCGATTGTATTTGTGTTGCACACGTTTTTATCGGCCA AAGTCACTCGTATGGGACTGCTTGTATGAGCAACAAAAAATCAGAAAAGAGCCTTGACTGTCACAAGAAATATTTCCACCTCAAAAAAAA AAAAGCACAAAAAGAAACTCTTTGCTCTCCTTCAGCACAGTGCCTTCCCAAGGACCTGCAAATAACTGCTGAACCATAACCGTGTTTAAA GAAGAGCCTACCTTTCACAGTCTACCTTGGCCAGATATTCTAGCACTCTAAAAGGCTCCAAAATGAAGCTGTTGATTTATTCTCATTTCA AAATATGGTTTATGAGTAATTAGGTTTATTTCTACTGCTAAAAAGAATGGCTCATTGTTTTCTTTTTTTTTCATTGTTTTCATTTTTAGA CATAATCAAATACCCAAGCATTGTTTTCTTTTTCTTCTCCCTGTAGGATTTGTGTTGTGCTTAGCCTTGATCTCTTGTTCAGAACAATTG TCCCTTCCCAGGTGCTAGCTTGCAGCAGCCTGTTGCTTCCTGAGCATTCCAGATAGGTCGTATGTCTTGGAATTTACTGTCCTCACTAGC TCCTTCCACCATAGGAAGTCCTTGAATTGTATCACCAAAGGGTTGTTCCATTTGCCCTGGATCTCCCTCTATCTCAGCCTGGCCATCACT TCCCACCTTATCCCAAGCTTTGCCACTGTCTCTAGGACTTAGAACTTGTAAATTTGATTTGCCTTGCCTTCTACTTCCTTTCTAGTGGTG ACTGAGTTGAAAAGCAAGTTGGAAGCCACTGCTTTTAAAGAAAAGTTTTGCTTGGTTTAGGTTTTTCCAATTTTATTTTTGTTAGGAGCC AGGGGATAAGATTTATTTTAAATGAAAATCCTCTTCCTAGGTTAAGCCATTTTTTTTATTGCTTACCAAATGTGCCTTTGGTTAGGGTTA GTGGAGCTTTATTAGTCACTATTTGAATAACTGGAAATCACTGCCATTTCCAGGAGATCACCTATCCTAGTTTTGAGGAATAGTCATTGA GGTGGGTTTCCTTAATGGCATCTCTTCTAGTAGGCAGATCTGTTTGAACAAGATAAATCCTAAAGAGCCAGCCTGCTTGAGGAGTAGACT TGGTGGGTGAAGCCAGCAATTCCGCACAAACGTCATGTTGAATTGTTTTGGGCTGCCCAAAAACAACAGGATGCAGCATCCTGGCTGTGG CCTGGCCCTTTGTGGCAGCAGTGGCATGGACAAGCAACTGCTAATTCGAGACTTACTATTGGCTTCACAGCACACCCTACAGTGAGCAGG GTGATGAGACCGTGGAACAGCTACCTGCTTTTGGTTAAGATTGCCAGATATCATTAGGACACAGTAGCAGCAAGAATGCTGATTTTGTAG TGTTAGAAAATGAACTCAGCTTGTTTTTCCTAATTTTGAAGGTGGTATATATCTGCAAACATTTAAAATGGTATAATATCATATAAAATG TCAAAATTAGCACAGTCCCTGGATCTCAAAGAATAGGTAATATTGACTTGGATGTTCTTTATGCTCTCTGAAGAAAGGTCTAGGGAAAGT TCTTGTTTGCTTGATTGATCAAGAGTGCCACGGAAGAATGTGAGCGCTGTGGAGGGTGGAGGAGGGTGTCACTTCAGATGGGGCAGGCAC AGGGGGAGAAAAGAAGAGAAAAACACACCTGTGTGCAAAATGAGCTATTTGGTTTCAGTGCGGCCTGACCGATGGGGAGGACCCATGAGC AGAGAGAGTTCTAGGTCAACATTGTAACTCCATTGTCCTCCTTCACCCATAAGTCAGTCCTCCTTCCTCATTACAGTGAAACCAACAATA TGCAGAGGTTGGGGAGAGATGCCTGTTCTTCCCCCAGCTTCATATAATTGTCAAAGTTCCAAAAATGAATTATCTGAACTGCTTAAAACT GGAAATTAAAATCTAGACAAGAATATGTCTTTCAAGAGCTTTTTATGTTTTGAAAGTTCATAAACCTAAGATTGGCTCCATCTGAGATAA ATTTTCTTTTCTTTTTTTTTTTGAGACGGAGTCTCGTTCTGTCTCCCAGGCTGGAGTGCAGTGGCATGATCTCGGCTCACTGCAACCTCC ACCTCCTAGGTTCAAGTGATTCTCCTGAGTAGCTGGGGTTATAGCTACCCACCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGGC AGGTTTTCACCATGTTGGCTAGGCTGGTCTTGAACTCCCGACCTCAAGTGATCCACCTGCCTTGGCCTCCCAAAGTGCTGGGATTATAGG TGTGAGCCCCCGTGCCTGGCCCACAATAAATTTTCATTTCAGAGAAGGAAAAAAATCTCTTGAACGTCCAGAAATGATTTCTGGAATCAG AATTTCAATATGTAATACCCTCAGGTAGGCAATCTTGAACCCTCTATGCAGTGAGAGCATTATTAATATGAGATGTTGAATGATGCCTTT ACAGACTTCAGCAGCAAAGCCATTTGGTTGAGGTTTTCTGTGTTAATGTGAAAAGCTAAGCCACTGAGATTTGCAGGGGAGCTTCTGAGC CACCCTGCTTGTTGGTTATATGAGGATGTAAAATAGGTGGAATTAAAATGTGAGCAGGAAAGGCAAGGCATGTGTGCATTTTCACTCATT TTGGTCAAGGTTAAACTGACATGTATAGCACTGAGGTCTGTAGGGTTCTTAATATCTTTTGAGTCTTGCTGTGAAATGAAAGTGTGGGAG GTTTCCTTTGTCCATTAGCAGCCCCAAGAACCAGAACCCTTTTGCTGCTTTTCTTACATACCTAACAGCTCTCCAGTCATGATGACCAAG GTTGTTCTTCAATCAAATGTGTTTGTGGGATTTTCAGTCCGCAAATGAAGTGCTCTCTAATGAATGGGACACCATGATAAATATGTATTT ATATTTAGATGCCAAAGTATGGCAAATTATTTCCAAATGATAACTACAAATGGGAATTTTCGATATTCTACCTTTTTTATAGAACCAGCT CACTTTTCATTTCTTTTTCATTTTGAATTAAGAAAATTGTTGAGGATGTGGTGGGTTCCAGTGTGTGGAATGGAAAGGAAACTGCAGAAT AGTGTCTGCTCCCCATTCAGAGGGACTGCTTCCTGTGCCCCCCAGACCCGGGGCTTCGACAGCTTCTCCACATTCCACACAGATGCCTAG GAGCAGCGAGTTGGTATATGAAAAGTCTCCCACCTTTTCTCCTAAAACTTCTCTCCTTTCTCTCCATAAAAAGAAAAGGAAAGGAACAAA AGAAAAACATTCAGTTTTTCTTTTTCTGAAAAAGGTAAGTCCTTTCCTGAAGTCATCAAATGAAACATTATCTGGAAATTAGTTTCTAAT GTTGTATATGAAGAAATACTTAAATATAAGTTCCTGCAGTATTTATTAGATAGTTGTAACTGTAAACTCACCTCCCTAGTAGATAAGAGT TTCAGGTTAAATACTGGAACATATATAGGCAGTCAAAAATACTACTTTAAATGTCATTCACCTATTTTAAAGCCATGTTTTAGCACTTTT TAGGCCAAAGAAGGTCTGATAGTGCCTGTTTTTATGTTCTGTACTCTCACAAACTTTGTTACTCAAAATTATTGCATGGCAGGAGAGATT GGATTATTTATTTCTTATATTTTTATAAGTAAAAAAATCTTTCTAAACAACAAATACCTAACATTATTACTGATTGTTTTCCTAATTTAT CCTCCTAAGTTGAATGGTAACAAAGCTTTTCCAGCTGAATGAATGCACTTAGCTGATAAACCAGAATTTGTTCTTTTTTTTCCTTCTTTT TTTTTTGAGACAGGTTCTCACTCTGTCACCGAGGTTGGAGTGCAGTGGTATGATCATAGCTGACTGCAGCCTCAACCTTCTGGGCTCAAA TGATCCTTTCACCTCAGCCTCCTGAGTAGCTGGGACCACAGGTGTGTGCCACCACACCTGGCTAATTTTTATGGATTTTTTTTTCTTTTT TTTTTTTCGCCATGTTGCCCAGGCTGGTCTTGAACTCTTGGCACTCAAGCAGTCCTTCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAG ATGTGAGCCACTGCACCTGGCCCCAGAAATTATGCTTAAAAAAAAAATTAAGCTGTGTGGAATCTGGACAAGGCTATGTTTCTCCTAGAA ACAGGTTTTGCTGTAAATGGTTTTGATGGGCGAAAGTGTGAGAAAAGGTTATAATAGATTCTTTTTTTTAATTTTGTGAGAAATTCCAGG TCTTCTTGCTTAACTTATATGCATGTGGATATATTTGTTTTCAAAGCCATGGAAGAATCTCTGTTCATATATTTTAATGCAAATTACCTT GTATGCTGCTATGCAAATTCTATTAAAAGGCCTACCTGCTTAAGAATTAAACATTTTTGAAACTTTCAGGGAAGACCTGTAGACTCAAGC ACTTTCTCTGCTTTTTTGTATCTTATCTTGGACACTTATGCTGAATTATGTTCTTATTATTTTCACTGGTTATAAGCTATTCCTTGTACA TAATATTTAAACTATCCAAATATCCAGCATACATTTCCATGTGGCTGCCATCGGCTGTTGATGCCATGAATGAAATGGCTGGTTAGAAAG CCAAAGGTCTTCTTTTTTCAATTCCTAATGAATAAGTAAAATGCCAGATCTCTTTGGTCTCAAAGCAAATTGCTCTGATCAGATCAAATA TCTATGTAATGAAAAGAGACTTACTTAAATTTGGGATTCTGCTTAAACTTTAAGTTGAATTTGACTGTAGTCATTCATTCTTTTTATATA TCTCTGTCAGGTATGACATTAATTACCAGGTGGTATTATACTCTACTTTGAGTTTGGACATCACTTTCAGTTAAATTTCTGTTGTTATTG TGGCTTTTTTTTTTTTTTAACCCCACTGAAGATGGAAGTAGAGCAGTCTGCCATCTCCTGCTGTTCTTTCTCTGTGCCCCCTAATTGCTT GGTAATCTAAAATTATTCTGACTTTCCACATACTGTCTTTAAAAACCAATTGTAGCAATCTGCCCGCCTCCACCCTTTAAGCTAAATCTT TCACTGTGCTGGATACATAGACACTCGATAAATGTGTGATGATAGTTCTAAAATAATTATGCTATATATCAGGGTTCTGTATTTTTGAGC AATATCATTATTCCTATGCTGTGATGTTAAATGGAATTTATTTTACACTAGTAATAGACTGCTTAAGTGGCTGATTTGAAACCTTTCTCT AAAAAAACAAAAACATCTGGCAGATGAGTGACACAAATTCATTCTCTTAAAGGATAGAATTTCAAGTTAAGGATAAGGCACAATAAATAG GCACATAGAGGACATCTGTTTTTGTTTTTGGTTTTGGTTTTGTTTTTTTTTGTCTCTCTGACTAGCTAAACTGCCAACTAGAAGAATGGT TGTTATGTAGTAACTCAGAAGAATCTTTTAATAAGTTTCTTCTTTTGTTTCAAAACAAACTTGAGCTTCATTTCTTGCCACCTCTATTCT TTCTTCCCACGTTGGGTGACTGAACTGATGCTTATTCTAGTTTTAGAAGAGGATCCACATTTAATGTAAGGCATAAATATGCCTTTTGCA AATTATTGCTTGTTCTCCAGTGAACATTTGATCATATTCAACAGAAATCCACCATATAAACCATAATCCTTGAATTGCCCCTTTTAAAAT AGATTGGTTAAAACCAAAAACCTATAAGAGAGAAATGATATTTCATTGTATTGTAGGTTTGGGAATCCTGGTTAGATTTATAATTTCTGG CCGGGTGCGGTGGCTCATGCCTGTATTCCCAGTACTTTGGGAGCCCAAGGTGGGTGGATCACCTGAGGTAAGGAGTTTGAGACCAGCCTG GCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAGTTAGCTGGGCATGGTGGTGCGCGCCTGTGGTCCCAGCTACTCGGGAGG CTGAGGTGGGAGAATCCCTTGAACCCAGGAGGCAGAAGTTGCAGTGAGCTGAGATCATGCCATTGCACTCCAGCCTGGGCAACAGAGCGA GACTTCATCTCCAAAAAAAGAAAAAGAAGAAAAAGATTTATAATTTCTGAGTCCCCTAAGTCCCTTTCTCAGTTTGCAATAATCTTACGT CCATGCTATTGACACTAATTTTGAAACTGGAAAGCTAATTAATGACATATTCATGTGTTCTTTCATCTAATAAACATTTATTAATGTATA GTTCTACACCAGGCATTCTGAAGGGTCCAAAAGAAAGTTCCTGCCCTCTAGTAGCACATAATCCGTTATTTCTCAGCACACCATGCCATC TGTTTATCATTCAGCAGTTAAGTAATTCATCACTTCATATTTTTACCAAAGTATATTTACAAGTCTGTTTATCTGGATCTGGCAAACTGG AAAATGTTTGAAGGGATACTCAGGCTTTGATCCATGCCAACATGAAAGGACTCCAAGCACATTTAAGTAGGCTGGTCTTTTCATCATGCA TGATTTTTTTTTTAGTGCAAATTTAGACTTTAGTTTGGGAAAGAGAACAGTATACAGTATCCTTTGTAAGATAAATCACAACAACAAAAA TTAAGTTTTATTGCACAAAGTAGATAAATGAGAAAGTCTTTCTTAAAAAATGCTTCTTTAACTGTAACAGCAAAACTAAATGCATATTTT ATCAACCCCTTATTTCTAATTGCTGTATTCATTTCCACCCTTAAACTATTTAAGCATTTCATCTGCTGAAAGTCCTTATATACATGGTAG ACGGAATATTTCTCCATTAATGATAGATCAAAATGAAGATATTTAAAAATTAACAAAATCAGGCCAAGGCAGGAGGATCACTTTAGCCCA GGAGGTCCAGACCAGCCTGGGCAACACAGCGGGACCCCGACTCCATTTAAAAAATTAAAAAAAAAAAAAAAACTTTTAACATTTAAAAAA TAAAAATTAACAAAATTTCACTTATTCCAGGACACGCTGGCATTTGGACTCAATGAAAAGGGCACCTAAAGAAAATAAGGCTGACTGAAT GTTTTCCATAATTTTCACACAATAACAGTCCCTTTCTATCCAGCTTGCCTTCCATTTATCTCTAGGGTTAGCTTTTCAGGCAACATCCTT GGTCATTGCCCAGAAAGTACCTGAGCTATCAGTGATTGGAATGGCACAGGAAACCGAATCACATGGGTGCCCTCCCCTTGGTTTTCAAGT ATCTTGGAGTTGTGCACAAAAATTAGGTCATGCCTTCAGTGTCTTGTTCTTTAAACCTACCCTTTGACAATCAGGTGCTAATGATTGTAT ACTATTAAAACCAGCACATAAGTATTGTAAATGTGTGTTCCTCCTAGGTTGGAAGAAATGTCTTTCCTTCTATCTGGGTCCTGTTAAAGC GGGTGTCAGTTGTGTCTTTTCACCTCGATTTGTGAATTAATAGAATTGGGGGGAGAGGAAATGATGATGTCAATTAAGTTTCAGGTTTGG CATGATCATCATTCTCGATGATATTCTCACTTTGTCGCAAATCTGCCCTTATCGTAAGAACAAGTTTCAGAATTTTCCCTCCACTATACG ACTCCAGTATTATGTTTACAATCCATTGGATGAGTGCAGCATTATAAGACCTTGGTGCCCAGAAAAATCTGTCCTTTTTGGTACCAAACC TGAGGTCTTTTGGAAGATAATGTAGAAAACCACTACCTATTGAAGGCCTGTTTTGGCTAATCTGTGCAAACTCTGATGATACCTGCTTAT GTGGATTCTTTTCCACACTGCTTTCATTTTTAAGTATAAAGACTTAGAAAACTAGAATAATGCTTTTACAAATAATTAAAAGTATGTGAT GTTCTGGGTTTTTTCCTTCTTTTTAGAACCCTGTATTTAAACAAGCCTTCTTTTTAAGTCTTGTTTGAAATTTAAGTCTCAGATCTTCTG GATACCAAATCAAAAACCCAACGCGTAAAACAGGGCAGTATTTGTGTTCCTAATTTTAAAAAGCTTTATGTATACTCTATAAATATAGAT GCATAAACAACACTTCCCCTTGAGTAGCACATCAACATACAGCATTGTACATTACAATGAAAATGTGTAACTTAAGGGTATTATATATAT AAATACATATATACCTTTGTAACCTTTATACTGTAAATAAAAAAGTTGCTTTAGTCA >17085_17085_2_CLEC16A-SNTB2_CLEC16A_chr16_11076848_ENST00000409790_SNTB2_chr16_69304046_ENST00000336278_length(amino acids)=562AA_BP=357 MFGRSRSWVGGGHGKTSRNIHSLDHLKYLYHVLTKNTTVTEQNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSG RYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFN HPESMVRIAVRTITLNVYKVSLDNQAMLHYIRDKTAVPYFSNLVWFIGSHVIELDDCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILII NCEFLNDVLTDHLLNRLFLPLYVYSLENQDKGGERPKISLPVSLYLLSQVFLIIHHAPLVNSLAEVILNGDLSEMYAKTEQDIQRSSAKL DGGRQQWRPVLMAVTEKDLLLYDCMPWTRDAWASPCHSYPLVATRLVHSGSGCRSPSLGSDLTFATRTGSRQGIEMHLFRVETHRDLSSW TRILVQGCHAAAELIKEVSLGCMLNGQEVRLTIHYENGFTISRENGGSSSILYRYPFERLKMSADDGIRNLYLDFGGPEGELTMDLHSCP KPIVFVLHTFLSAKVTRMGLLV -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for CLEC16A-SNTB2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for CLEC16A-SNTB2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for CLEC16A-SNTB2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CLEC16A | C0011854 | Diabetes Mellitus, Insulin-Dependent | 2 | CTD_human |
| Hgene | CLEC16A | C0026769 | Multiple Sclerosis | 2 | CTD_human |
| Hgene | CLEC16A | C0162538 | Immunoglobulin A deficiency (disorder) | 2 | CTD_human |
| Hgene | CLEC16A | C0205734 | Diabetes, Autoimmune | 2 | CTD_human |
| Hgene | CLEC16A | C0342302 | Brittle diabetes | 2 | CTD_human |
| Hgene | CLEC16A | C0751324 | Multiple Sclerosis, Acute Fulminating | 2 | CTD_human |
| Hgene | CLEC16A | C3837958 | Diabetes Mellitus, Ketosis-Prone | 2 | CTD_human |
| Hgene | CLEC16A | C4554117 | Diabetes Mellitus, Sudden-Onset | 2 | CTD_human |
| Hgene | CLEC16A | C0001403 | Addison Disease | 1 | CTD_human |
| Hgene | CLEC16A | C0008312 | Primary biliary cirrhosis | 1 | CTD_human |
| Hgene | CLEC16A | C0023892 | Biliary cirrhosis | 1 | CTD_human |
| Hgene | CLEC16A | C0024141 | Lupus Erythematosus, Systemic | 1 | CTD_human |
| Hgene | CLEC16A | C0238065 | Secondary Biliary Cholangitis | 1 | CTD_human |
| Hgene | CLEC16A | C0242380 | Libman-Sacks Disease | 1 | CTD_human |
| Hgene | CLEC16A | C4551595 | Biliary Cirrhosis, Primary, 1 | 1 | CTD_human |
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