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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:FUS-DDIT3 (FusionGDB2 ID:HG2521TG1649)

Fusion Gene Summary for FUS-DDIT3

check button Fusion gene summary
Fusion gene informationFusion gene name: FUS-DDIT3
Fusion gene ID: hg2521tg1649
HgeneTgene
Gene symbol

FUS

DDIT3

Gene ID

2521

1649

Gene nameFUS RNA binding proteinDNA damage inducible transcript 3
SynonymsALS6|ETM4|FUS1|HNRNPP2|POMP75|TLSAltDDIT3|C/EBPzeta|CEBPZ|CHOP|CHOP-10|CHOP10|GADD153
Cytomap('FUS')('DDIT3')

16p11.2

12q13.3

Type of geneprotein-codingprotein-coding
DescriptionRNA-binding protein FUS75 kDa DNA-pairing proteinfus-like proteinfused in sarcomafusion gene in myxoid liposarcomaheterogeneous nuclear ribonucleoprotein P2oncogene FUSoncogene TLStranslocated in liposarcoma proteinDNA damage-inducible transcript 3 proteinC/EBP zetaCCAAT/enhancer-binding protein homologous proteinalternative DDIT3 proteinc/EBP-homologous protein 10growth arrest and DNA damage-inducible protein GADD153
Modification date2020032920200313
UniProtAcc

P35637

P0DPQ6

Ensembl transtripts involved in fusion geneENST00000474990, ENST00000254108, 
ENST00000380244, ENST00000568685, 
ENST00000254108, ENST00000380244, 
ENST00000568685, ENST00000474990, 
Fusion gene scores* DoF score37 X 37 X 16=219042 X 11 X 4=88
# samples 448
** MAII scorelog2(44/21904*10)=-5.63754701773324
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/88*10)=-0.137503523749935
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FUS [Title/Abstract] AND DDIT3 [Title/Abstract] AND fusion [Title/Abstract]

FUS-DDIT3 Fusion Protein-Driven IGF-IR Signaling is a Therapeutic Target in Myxoid Liposarcoma (pmid:  28637688)
Most frequent breakpointFUS(31198157)-DDIT3(57911701), # samples:2
FUS(31198157)-DDIT3(57911537), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFUS

GO:0006355

regulation of transcription, DNA-templated

26124092

HgeneFUS

GO:0006357

regulation of transcription by RNA polymerase II

25453086

HgeneFUS

GO:0008380

RNA splicing

26124092

HgeneFUS

GO:0043484

regulation of RNA splicing

25453086|27731383

HgeneFUS

GO:0048255

mRNA stabilization

27378374

HgeneFUS

GO:0051260

protein homooligomerization

25453086

HgeneFUS

GO:1905168

positive regulation of double-strand break repair via homologous recombination

10567410

TgeneDDIT3

GO:0000122

negative regulation of transcription by RNA polymerase II

18940792

TgeneDDIT3

GO:0006986

response to unfolded protein

18940792

TgeneDDIT3

GO:0007050

cell cycle arrest

22496745

TgeneDDIT3

GO:0032792

negative regulation of CREB transcription factor activity

8622660

TgeneDDIT3

GO:0034976

response to endoplasmic reticulum stress

18940792|19061639|20829347

TgeneDDIT3

GO:0042789

mRNA transcription by RNA polymerase II

14667815

TgeneDDIT3

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

17872950

TgeneDDIT3

GO:0043433

negative regulation of DNA-binding transcription factor activity

16434966

TgeneDDIT3

GO:0045454

cell redox homeostasis

14667815

TgeneDDIT3

GO:0045892

negative regulation of transcription, DNA-templated

18940792

TgeneDDIT3

GO:0045893

positive regulation of transcription, DNA-templated

15322075|15775988

TgeneDDIT3

GO:0045944

positive regulation of transcription by RNA polymerase II

22065586

TgeneDDIT3

GO:0070059

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

18940792|20829347

TgeneDDIT3

GO:1903026

negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding

8622660

TgeneDDIT3

GO:1990440

positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

15322075|24939851

TgeneDDIT3

GO:2000016

negative regulation of determination of dorsal identity

16434966



check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4liposarcomaAJ301613FUSchr16

31202431

DDIT3chr12

57912676
ChimerDB4SARCTCGA-Z4-A9VC-01AFUSchr16

31199678

-DDIT3chr12

57911536

-
ChimerKB3..FUSchr16

31193985

+DDIT3chr12

57911302

-
ChimerKB3..FUSchr16

31198157

+DDIT3chr12

57911536

-
ChimerKB3..FUSchr16

31198614

+DDIT3chr12

57912677

-
ChimerKB3..FUSchr16

31202431

+DDIT3chr12

57912676

-
ChimerKB4..FUSchr16

31193985

+DDIT3chr12

57911302

-
ChimerKB4..FUSchr16

31198157

+DDIT3chr12

57911536

-
ChimerKB4..FUSchr16

31200443

+DDIT3chr12

31200443

-


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Fusion Gene ORF analysis for FUS-DDIT3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-5UTRENST00000474990ENST00000346473FUSchr16

31199678

-DDIT3chr12

57911536

-
3UTR-5UTRENST00000474990ENST00000346473FUSchr16

31198157

+DDIT3chr12

57911536

-
3UTR-5UTRENST00000474990ENST00000547303FUSchr16

31199678

-DDIT3chr12

57911536

-
3UTR-5UTRENST00000474990ENST00000547303FUSchr16

31198157

+DDIT3chr12

57911536

-
3UTR-5UTRENST00000474990ENST00000551116FUSchr16

31199678

-DDIT3chr12

57911536

-
3UTR-5UTRENST00000474990ENST00000551116FUSchr16

31198157

+DDIT3chr12

57911536

-
3UTR-5UTRENST00000474990ENST00000552740FUSchr16

31199678

-DDIT3chr12

57911536

-
3UTR-5UTRENST00000474990ENST00000552740FUSchr16

31198157

+DDIT3chr12

57911536

-
5CDS-5UTRENST00000254108ENST00000346473FUSchr16

31199678

-DDIT3chr12

57911536

-
5CDS-5UTRENST00000254108ENST00000346473FUSchr16

31198157

+DDIT3chr12

57911536

-
5CDS-5UTRENST00000254108ENST00000547303FUSchr16

31199678

-DDIT3chr12

57911536

-
5CDS-5UTRENST00000254108ENST00000547303FUSchr16

31198157

+DDIT3chr12

57911536

-
5CDS-5UTRENST00000254108ENST00000551116FUSchr16

31199678

-DDIT3chr12

57911536

-
5CDS-5UTRENST00000254108ENST00000551116FUSchr16

31193985

+DDIT3chr12

57911302

-
5CDS-5UTRENST00000254108ENST00000551116FUSchr16

31198157

+DDIT3chr12

57911536

-
5CDS-5UTRENST00000254108ENST00000552740FUSchr16

31199678

-DDIT3chr12

57911536

-
5CDS-5UTRENST00000254108ENST00000552740FUSchr16

31193985

+DDIT3chr12

57911302

-
5CDS-5UTRENST00000254108ENST00000552740FUSchr16

31198157

+DDIT3chr12

57911536

-
5CDS-5UTRENST00000380244ENST00000346473FUSchr16

31199678

-DDIT3chr12

57911536

-
5CDS-5UTRENST00000380244ENST00000346473FUSchr16

31198157

+DDIT3chr12

57911536

-
5CDS-5UTRENST00000380244ENST00000547303FUSchr16

31199678

-DDIT3chr12

57911536

-
5CDS-5UTRENST00000380244ENST00000547303FUSchr16

31198157

+DDIT3chr12

57911536

-
5CDS-5UTRENST00000380244ENST00000551116FUSchr16

31199678

-DDIT3chr12

57911536

-
5CDS-5UTRENST00000380244ENST00000551116FUSchr16

31193985

+DDIT3chr12

57911302

-
5CDS-5UTRENST00000380244ENST00000551116FUSchr16

31198157

+DDIT3chr12

57911536

-
5CDS-5UTRENST00000380244ENST00000552740FUSchr16

31199678

-DDIT3chr12

57911536

-
5CDS-5UTRENST00000380244ENST00000552740FUSchr16

31193985

+DDIT3chr12

57911302

-
5CDS-5UTRENST00000380244ENST00000552740FUSchr16

31198157

+DDIT3chr12

57911536

-
5CDS-5UTRENST00000568685ENST00000346473FUSchr16

31199678

-DDIT3chr12

57911536

-
5CDS-5UTRENST00000568685ENST00000346473FUSchr16

31198157

+DDIT3chr12

57911536

-
5CDS-5UTRENST00000568685ENST00000547303FUSchr16

31199678

-DDIT3chr12

57911536

-
5CDS-5UTRENST00000568685ENST00000547303FUSchr16

31198157

+DDIT3chr12

57911536

-
5CDS-5UTRENST00000568685ENST00000551116FUSchr16

31199678

-DDIT3chr12

57911536

-
5CDS-5UTRENST00000568685ENST00000551116FUSchr16

31193985

+DDIT3chr12

57911302

-
5CDS-5UTRENST00000568685ENST00000551116FUSchr16

31198157

+DDIT3chr12

57911536

-
5CDS-5UTRENST00000568685ENST00000552740FUSchr16

31199678

-DDIT3chr12

57911536

-
5CDS-5UTRENST00000568685ENST00000552740FUSchr16

31193985

+DDIT3chr12

57911302

-
5CDS-5UTRENST00000568685ENST00000552740FUSchr16

31198157

+DDIT3chr12

57911536

-
5CDS-intronENST00000254108ENST00000346473FUSchr16

31202431

DDIT3chr12

57912676

5CDS-intronENST00000254108ENST00000346473FUSchr16

31193985

+DDIT3chr12

57911302

-
5CDS-intronENST00000254108ENST00000346473FUSchr16

31202431

+DDIT3chr12

57912676

-
5CDS-intronENST00000254108ENST00000547303FUSchr16

31202431

DDIT3chr12

57912676

5CDS-intronENST00000254108ENST00000547303FUSchr16

31193985

+DDIT3chr12

57911302

-
5CDS-intronENST00000254108ENST00000547303FUSchr16

31202431

+DDIT3chr12

57912676

-
5CDS-intronENST00000254108ENST00000551116FUSchr16

31202431

DDIT3chr12

57912676

5CDS-intronENST00000254108ENST00000551116FUSchr16

31202431

+DDIT3chr12

57912676

-
5CDS-intronENST00000254108ENST00000552740FUSchr16

31202431

DDIT3chr12

57912676

5CDS-intronENST00000254108ENST00000552740FUSchr16

31202431

+DDIT3chr12

57912676

-
5CDS-intronENST00000380244ENST00000346473FUSchr16

31202431

DDIT3chr12

57912676

5CDS-intronENST00000380244ENST00000346473FUSchr16

31193985

+DDIT3chr12

57911302

-
5CDS-intronENST00000380244ENST00000346473FUSchr16

31202431

+DDIT3chr12

57912676

-
5CDS-intronENST00000380244ENST00000547303FUSchr16

31202431

DDIT3chr12

57912676

5CDS-intronENST00000380244ENST00000547303FUSchr16

31193985

+DDIT3chr12

57911302

-
5CDS-intronENST00000380244ENST00000547303FUSchr16

31202431

+DDIT3chr12

57912676

-
5CDS-intronENST00000380244ENST00000551116FUSchr16

31202431

DDIT3chr12

57912676

5CDS-intronENST00000380244ENST00000551116FUSchr16

31202431

+DDIT3chr12

57912676

-
5CDS-intronENST00000380244ENST00000552740FUSchr16

31202431

DDIT3chr12

57912676

5CDS-intronENST00000380244ENST00000552740FUSchr16

31202431

+DDIT3chr12

57912676

-
5CDS-intronENST00000568685ENST00000346473FUSchr16

31202431

DDIT3chr12

57912676

5CDS-intronENST00000568685ENST00000346473FUSchr16

31193985

+DDIT3chr12

57911302

-
5CDS-intronENST00000568685ENST00000346473FUSchr16

31202431

+DDIT3chr12

57912676

-
5CDS-intronENST00000568685ENST00000547303FUSchr16

31202431

DDIT3chr12

57912676

5CDS-intronENST00000568685ENST00000547303FUSchr16

31193985

+DDIT3chr12

57911302

-
5CDS-intronENST00000568685ENST00000547303FUSchr16

31202431

+DDIT3chr12

57912676

-
5CDS-intronENST00000568685ENST00000551116FUSchr16

31202431

DDIT3chr12

57912676

5CDS-intronENST00000568685ENST00000551116FUSchr16

31202431

+DDIT3chr12

57912676

-
5CDS-intronENST00000568685ENST00000552740FUSchr16

31202431

DDIT3chr12

57912676

5CDS-intronENST00000568685ENST00000552740FUSchr16

31202431

+DDIT3chr12

57912676

-
intron-5UTRENST00000474990ENST00000551116FUSchr16

31193985

+DDIT3chr12

57911302

-
intron-5UTRENST00000474990ENST00000552740FUSchr16

31193985

+DDIT3chr12

57911302

-
intron-intronENST00000254108ENST00000346473FUSchr16

31198614

+DDIT3chr12

57912677

-
intron-intronENST00000254108ENST00000346473FUSchr16

31200443

+DDIT3chr12

31200443

-
intron-intronENST00000254108ENST00000547303FUSchr16

31198614

+DDIT3chr12

57912677

-
intron-intronENST00000254108ENST00000547303FUSchr16

31200443

+DDIT3chr12

31200443

-
intron-intronENST00000254108ENST00000551116FUSchr16

31198614

+DDIT3chr12

57912677

-
intron-intronENST00000254108ENST00000551116FUSchr16

31200443

+DDIT3chr12

31200443

-
intron-intronENST00000254108ENST00000552740FUSchr16

31198614

+DDIT3chr12

57912677

-
intron-intronENST00000254108ENST00000552740FUSchr16

31200443

+DDIT3chr12

31200443

-
intron-intronENST00000380244ENST00000346473FUSchr16

31198614

+DDIT3chr12

57912677

-
intron-intronENST00000380244ENST00000346473FUSchr16

31200443

+DDIT3chr12

31200443

-
intron-intronENST00000380244ENST00000547303FUSchr16

31198614

+DDIT3chr12

57912677

-
intron-intronENST00000380244ENST00000547303FUSchr16

31200443

+DDIT3chr12

31200443

-
intron-intronENST00000380244ENST00000551116FUSchr16

31198614

+DDIT3chr12

57912677

-
intron-intronENST00000380244ENST00000551116FUSchr16

31200443

+DDIT3chr12

31200443

-
intron-intronENST00000380244ENST00000552740FUSchr16

31198614

+DDIT3chr12

57912677

-
intron-intronENST00000380244ENST00000552740FUSchr16

31200443

+DDIT3chr12

31200443

-
intron-intronENST00000474990ENST00000346473FUSchr16

31202431

DDIT3chr12

57912676

intron-intronENST00000474990ENST00000346473FUSchr16

31193985

+DDIT3chr12

57911302

-
intron-intronENST00000474990ENST00000346473FUSchr16

31198614

+DDIT3chr12

57912677

-
intron-intronENST00000474990ENST00000346473FUSchr16

31202431

+DDIT3chr12

57912676

-
intron-intronENST00000474990ENST00000346473FUSchr16

31200443

+DDIT3chr12

31200443

-
intron-intronENST00000474990ENST00000547303FUSchr16

31202431

DDIT3chr12

57912676

intron-intronENST00000474990ENST00000547303FUSchr16

31193985

+DDIT3chr12

57911302

-
intron-intronENST00000474990ENST00000547303FUSchr16

31198614

+DDIT3chr12

57912677

-
intron-intronENST00000474990ENST00000547303FUSchr16

31202431

+DDIT3chr12

57912676

-
intron-intronENST00000474990ENST00000547303FUSchr16

31200443

+DDIT3chr12

31200443

-
intron-intronENST00000474990ENST00000551116FUSchr16

31202431

DDIT3chr12

57912676

intron-intronENST00000474990ENST00000551116FUSchr16

31198614

+DDIT3chr12

57912677

-
intron-intronENST00000474990ENST00000551116FUSchr16

31202431

+DDIT3chr12

57912676

-
intron-intronENST00000474990ENST00000551116FUSchr16

31200443

+DDIT3chr12

31200443

-
intron-intronENST00000474990ENST00000552740FUSchr16

31202431

DDIT3chr12

57912676

intron-intronENST00000474990ENST00000552740FUSchr16

31198614

+DDIT3chr12

57912677

-
intron-intronENST00000474990ENST00000552740FUSchr16

31202431

+DDIT3chr12

57912676

-
intron-intronENST00000474990ENST00000552740FUSchr16

31200443

+DDIT3chr12

31200443

-
intron-intronENST00000568685ENST00000346473FUSchr16

31198614

+DDIT3chr12

57912677

-
intron-intronENST00000568685ENST00000346473FUSchr16

31200443

+DDIT3chr12

31200443

-
intron-intronENST00000568685ENST00000547303FUSchr16

31198614

+DDIT3chr12

57912677

-
intron-intronENST00000568685ENST00000547303FUSchr16

31200443

+DDIT3chr12

31200443

-
intron-intronENST00000568685ENST00000551116FUSchr16

31198614

+DDIT3chr12

57912677

-
intron-intronENST00000568685ENST00000551116FUSchr16

31200443

+DDIT3chr12

31200443

-
intron-intronENST00000568685ENST00000552740FUSchr16

31198614

+DDIT3chr12

57912677

-
intron-intronENST00000568685ENST00000552740FUSchr16

31200443

+DDIT3chr12

31200443

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for FUS-DDIT3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)


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Fusion Protein Features for FUS-DDIT3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:31198157/:57911701)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FUS

P35637

DDIT3

P0DPQ6

FUNCTION: DNA/RNA-binding protein that plays a role in various cellular processes such as transcription regulation, RNA splicing, RNA transport, DNA repair and damage response (PubMed:27731383). Binds to nascent pre-mRNAs and acts as a molecular mediator between RNA polymerase II and U1 small nuclear ribonucleoprotein thereby coupling transcription and splicing (PubMed:26124092). Binds also its own pre-mRNA and autoregulates its expression; this autoregulation mechanism is mediated by non-sense-mediated decay (PubMed:24204307). Plays a role in DNA repair mechanisms by promoting D-loop formation and homologous recombination during DNA double-strand break repair (PubMed:10567410). In neuronal cells, plays crucial roles in dendritic spine formation and stability, RNA transport, mRNA stability and synaptic homeostasis (By similarity). {ECO:0000250|UniProtKB:P56959, ECO:0000269|PubMed:10567410, ECO:0000269|PubMed:24204307, ECO:0000269|PubMed:26124092, ECO:0000269|PubMed:27731383}.FUNCTION: [Isoform AltDDIT3]: Product of the upstream open reading frame (uORF) of DDIT3/CHOP that is specifically produced in absence of stress, thereby preventing translation of downstream stress effector DDIT3/CHOP. {ECO:0000250|UniProtKB:A0A2R8VHR8}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for FUS-DDIT3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for FUS-DDIT3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FUS-DDIT3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FUS-DDIT3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneFUSC1842675AMYOTROPHIC LATERAL SCLEROSIS 6 (disorder)5UNIPROT
HgeneFUSC3468114Juvenile amyotrophic lateral sclerosis5ORPHANET
HgeneFUSC0002736Amyotrophic Lateral Sclerosis2CTD_human;ORPHANET
HgeneFUSC0206634Liposarcoma, Myxoid2CTD_human;ORPHANET
HgeneFUSC0393554Amyotrophic Lateral Sclerosis With Dementia1CTD_human
HgeneFUSC0497327Dementia1GENOMICS_ENGLAND
HgeneFUSC0543859Amyotrophic Lateral Sclerosis, Guam Form1CTD_human
HgeneFUSC3539195TREMOR, HEREDITARY ESSENTIAL, 41CTD_human;UNIPROT
HgeneFUSC3888102Frontotemporal Dementia With Motor Neuron Disease1ORPHANET
TgeneC0206634Liposarcoma, Myxoid3CTD_human;ORPHANET
TgeneC0003949Asbestosis1CTD_human
TgeneC0006142Malignant neoplasm of breast1CTD_human
TgeneC0011616Contact Dermatitis1CTD_human
TgeneC0011854Diabetes Mellitus, Insulin-Dependent1CTD_human
TgeneC0015695Fatty Liver1CTD_human
TgeneC0017614Glaucoma, Suspect1CTD_human
TgeneC0021831Intestinal Diseases1CTD_human
TgeneC0027051Myocardial Infarction1CTD_human
TgeneC0027720Nephrosis1CTD_human
TgeneC0028754Obesity1CTD_human
TgeneC0028840Ocular Hypertension1CTD_human
TgeneC0041582Ulcer1CTD_human
TgeneC0087031Juvenile-Onset Still Disease1CTD_human
TgeneC0162351Contact hypersensitivity1CTD_human
TgeneC0205734Diabetes, Autoimmune1CTD_human
TgeneC0342302Brittle diabetes1CTD_human
TgeneC0678222Breast Carcinoma1CTD_human
TgeneC1257931Mammary Neoplasms, Human1CTD_human
TgeneC1458155Mammary Neoplasms1CTD_human
TgeneC2711227Steatohepatitis1CTD_human
TgeneC2930617Pulmonary Fibrosis - from Asbestos Exposure1CTD_human
TgeneC3495559Juvenile arthritis1CTD_human
TgeneC3714758Juvenile psoriatic arthritis1CTD_human
TgeneC3837958Diabetes Mellitus, Ketosis-Prone1CTD_human
TgeneC4552091Polyarthritis, Juvenile, Rheumatoid Factor Negative1CTD_human
TgeneC4554117Diabetes Mellitus, Sudden-Onset1CTD_human
TgeneC4704862Polyarthritis, Juvenile, Rheumatoid Factor Positive1CTD_human
TgeneC4704874Mammary Carcinoma, Human1CTD_human