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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ASPM-F13B (FusionGDB2 ID:HG259266TG2165)

Fusion Gene Summary for ASPM-F13B

check button Fusion gene summary
Fusion gene informationFusion gene name: ASPM-F13B
Fusion gene ID: hg259266tg2165
HgeneTgene
Gene symbol

ASPM

F13B

Gene ID

259266

2165

Gene nameassembly factor for spindle microtubulescoagulation factor XIII B chain
SynonymsASP|Calmbp1|MCPH5FXIIIB
Cytomap('ASPM')('F13B')

1q31.3

1q31.3

Type of geneprotein-codingprotein-coding
Descriptionabnormal spindle-like microcephaly-associated proteinabnormal spindle microtubule assemblyasp (abnormal spindle) homolog, microcephaly associatedcoagulation factor XIII B chainTGasecoagulation factor XIII, B polypeptidefibrin-stabilizing factor B subunitprotein-glutamine gamma-glutamyltransferase B chaintransglutaminase B chain
Modification date2020032820200313
UniProtAcc.

P05160

Ensembl transtripts involved in fusion geneENST00000294732, ENST00000367409, 
ENST00000367408, 
Fusion gene scores* DoF score3 X 3 X 2=182 X 3 X 2=12
# samples 32
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(2/12*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: ASPM [Title/Abstract] AND F13B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointASPM(197111461)-F13B(197008541), # samples:2
Anticipated loss of major functional domain due to fusion event.ASPM-F13B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ASPM-F13B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ASPM-F13B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ASPM-F13B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ASPM (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across F13B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-HS-A5NA-01AASPMchr1

197111461

-F13Bchr1

197008541

-
ChimerDB4SARCTCGA-HS-A5NA-01AASPMchr1

197111461

-F13Bchr1

197009865

-


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Fusion Gene ORF analysis for ASPM-F13B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000294732ENST00000490002ASPMchr1

197111461

-F13Bchr1

197009865

-
5CDS-5UTRENST00000367409ENST00000490002ASPMchr1

197111461

-F13Bchr1

197009865

-
5CDS-intronENST00000294732ENST00000490002ASPMchr1

197111461

-F13Bchr1

197008541

-
5CDS-intronENST00000367409ENST00000490002ASPMchr1

197111461

-F13Bchr1

197008541

-
In-frameENST00000294732ENST00000367412ASPMchr1

197111461

-F13Bchr1

197008541

-
In-frameENST00000294732ENST00000367412ASPMchr1

197111461

-F13Bchr1

197009865

-
In-frameENST00000367409ENST00000367412ASPMchr1

197111461

-F13Bchr1

197008541

-
In-frameENST00000367409ENST00000367412ASPMchr1

197111461

-F13Bchr1

197009865

-
intron-3CDSENST00000367408ENST00000367412ASPMchr1

197111461

-F13Bchr1

197008541

-
intron-3CDSENST00000367408ENST00000367412ASPMchr1

197111461

-F13Bchr1

197009865

-
intron-5UTRENST00000367408ENST00000490002ASPMchr1

197111461

-F13Bchr1

197009865

-
intron-intronENST00000367408ENST00000490002ASPMchr1

197111461

-F13Bchr1

197008541

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000294732ASPMchr1197111461-ENST00000367412F13Bchr1197008541-239921781612203680
ENST00000367409ASPMchr1197111461-ENST00000367412F13Bchr1197008541-239921781612203680
ENST00000294732ASPMchr1197111461-ENST00000367412F13Bchr1197009865-261321781612425754
ENST00000367409ASPMchr1197111461-ENST00000367412F13Bchr1197009865-261321781612425754

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000294732ENST00000367412ASPMchr1197111461-F13Bchr1197008541-0.0007931470.99920684
ENST00000367409ENST00000367412ASPMchr1197111461-F13Bchr1197008541-0.0007931470.99920684
ENST00000294732ENST00000367412ASPMchr1197111461-F13Bchr1197009865-0.0006351180.9993649
ENST00000367409ENST00000367412ASPMchr1197111461-F13Bchr1197009865-0.0006351180.9993649

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Fusion Genomic Features for ASPM-F13B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ASPM-F13B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:197111461/chr1:197008541)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.F13B

P05160

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin. {ECO:0000303|PubMed:21742792, ECO:0000303|PubMed:3021194}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneF13Bchr1:197111461chr1:197009865ENST00000367412912581_647579662.0DomainSushi 10
TgeneF13Bchr1:197111461chr1:197009865ENST00000367412912617_619579662.0MotifNote=Cell attachment site

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3271057_10786401893.0Coiled coilOntology_term=ECO:0000255
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3281057_10786403478.0Coiled coilOntology_term=ECO:0000255
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3271057_10786401893.0Coiled coilOntology_term=ECO:0000255
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3281057_10786403478.0Coiled coilOntology_term=ECO:0000255
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3271110_12616401893.0DomainCalponin-homology (CH) 2
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3271347_13786401893.0DomainIQ 1
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3271393_14226401893.0DomainIQ 2
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3271582_16136401893.0DomainIQ 3
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3271632_16616401893.0DomainIQ 4
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3271655_16846401893.0DomainIQ 5
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3271728_17576401893.0DomainIQ 6
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3271751_17826401893.0DomainIQ 7
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3271801_18306401893.0DomainIQ 8
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3271824_18536401893.0DomainIQ 9
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3271874_19036401893.0DomainIQ 10
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3271897_19286401893.0DomainIQ 11
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3271947_19786401893.0DomainIQ 12
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3271970_20016401893.0DomainIQ 13
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272020_20496401893.0DomainIQ 14
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272043_20746401893.0DomainIQ 15
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272093_21246401893.0DomainIQ 16
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272116_21476401893.0DomainIQ 17
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272166_21976401893.0DomainIQ 18
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272189_22186401893.0DomainIQ 19
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272239_22706401893.0DomainIQ 20
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272262_22936401893.0DomainIQ 21
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272311_23426401893.0DomainIQ 22
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272334_23656401893.0DomainIQ 23
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272384_24156401893.0DomainIQ 24
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272407_24386401893.0DomainIQ 25
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272457_24886401893.0DomainIQ 26
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272530_25616401893.0DomainIQ 27
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272624_26536401893.0DomainIQ 28
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272665_26966401893.0DomainIQ 29
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272688_27196401893.0DomainIQ 30
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272738_27676401893.0DomainIQ 31
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272859_28906401893.0DomainIQ 32
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272909_29386401893.0DomainIQ 33
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272932_29636401893.0DomainIQ 34
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3272954_29856401893.0DomainIQ 35
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3273029_30606401893.0DomainIQ 36
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3273079_31106401893.0DomainIQ 37
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3273181_32106401893.0DomainIQ 38
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-3273204_32356401893.0DomainIQ 39
HgeneASPMchr1:197111461chr1:197008541ENST00000294732-327920_10566401893.0DomainCalponin-homology (CH) 1
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3281110_12616403478.0DomainCalponin-homology (CH) 2
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3281347_13786403478.0DomainIQ 1
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3281393_14226403478.0DomainIQ 2
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3281582_16136403478.0DomainIQ 3
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3281632_16616403478.0DomainIQ 4
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3281655_16846403478.0DomainIQ 5
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3281728_17576403478.0DomainIQ 6
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3281751_17826403478.0DomainIQ 7
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3281801_18306403478.0DomainIQ 8
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3281824_18536403478.0DomainIQ 9
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3281874_19036403478.0DomainIQ 10
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3281897_19286403478.0DomainIQ 11
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3281947_19786403478.0DomainIQ 12
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3281970_20016403478.0DomainIQ 13
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282020_20496403478.0DomainIQ 14
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282043_20746403478.0DomainIQ 15
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282093_21246403478.0DomainIQ 16
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282116_21476403478.0DomainIQ 17
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282166_21976403478.0DomainIQ 18
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282189_22186403478.0DomainIQ 19
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282239_22706403478.0DomainIQ 20
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282262_22936403478.0DomainIQ 21
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282311_23426403478.0DomainIQ 22
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282334_23656403478.0DomainIQ 23
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282384_24156403478.0DomainIQ 24
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282407_24386403478.0DomainIQ 25
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282457_24886403478.0DomainIQ 26
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282530_25616403478.0DomainIQ 27
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282624_26536403478.0DomainIQ 28
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282665_26966403478.0DomainIQ 29
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282688_27196403478.0DomainIQ 30
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282738_27676403478.0DomainIQ 31
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282859_28906403478.0DomainIQ 32
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282909_29386403478.0DomainIQ 33
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282932_29636403478.0DomainIQ 34
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3282954_29856403478.0DomainIQ 35
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3283029_30606403478.0DomainIQ 36
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3283079_31106403478.0DomainIQ 37
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3283181_32106403478.0DomainIQ 38
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-3283204_32356403478.0DomainIQ 39
HgeneASPMchr1:197111461chr1:197008541ENST00000367409-328920_10566403478.0DomainCalponin-homology (CH) 1
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3271110_12616401893.0DomainCalponin-homology (CH) 2
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3271347_13786401893.0DomainIQ 1
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3271393_14226401893.0DomainIQ 2
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3271582_16136401893.0DomainIQ 3
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3271632_16616401893.0DomainIQ 4
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3271655_16846401893.0DomainIQ 5
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3271728_17576401893.0DomainIQ 6
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3271751_17826401893.0DomainIQ 7
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3271801_18306401893.0DomainIQ 8
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3271824_18536401893.0DomainIQ 9
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3271874_19036401893.0DomainIQ 10
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3271897_19286401893.0DomainIQ 11
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3271947_19786401893.0DomainIQ 12
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3271970_20016401893.0DomainIQ 13
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272020_20496401893.0DomainIQ 14
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272043_20746401893.0DomainIQ 15
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272093_21246401893.0DomainIQ 16
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272116_21476401893.0DomainIQ 17
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272166_21976401893.0DomainIQ 18
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272189_22186401893.0DomainIQ 19
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272239_22706401893.0DomainIQ 20
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272262_22936401893.0DomainIQ 21
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272311_23426401893.0DomainIQ 22
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272334_23656401893.0DomainIQ 23
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272384_24156401893.0DomainIQ 24
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272407_24386401893.0DomainIQ 25
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272457_24886401893.0DomainIQ 26
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272530_25616401893.0DomainIQ 27
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272624_26536401893.0DomainIQ 28
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272665_26966401893.0DomainIQ 29
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272688_27196401893.0DomainIQ 30
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272738_27676401893.0DomainIQ 31
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272859_28906401893.0DomainIQ 32
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272909_29386401893.0DomainIQ 33
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272932_29636401893.0DomainIQ 34
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3272954_29856401893.0DomainIQ 35
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3273029_30606401893.0DomainIQ 36
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3273079_31106401893.0DomainIQ 37
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3273181_32106401893.0DomainIQ 38
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-3273204_32356401893.0DomainIQ 39
HgeneASPMchr1:197111461chr1:197009865ENST00000294732-327920_10566401893.0DomainCalponin-homology (CH) 1
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3281110_12616403478.0DomainCalponin-homology (CH) 2
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3281347_13786403478.0DomainIQ 1
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3281393_14226403478.0DomainIQ 2
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3281582_16136403478.0DomainIQ 3
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3281632_16616403478.0DomainIQ 4
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3281655_16846403478.0DomainIQ 5
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3281728_17576403478.0DomainIQ 6
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3281751_17826403478.0DomainIQ 7
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3281801_18306403478.0DomainIQ 8
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3281824_18536403478.0DomainIQ 9
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3281874_19036403478.0DomainIQ 10
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3281897_19286403478.0DomainIQ 11
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3281947_19786403478.0DomainIQ 12
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3281970_20016403478.0DomainIQ 13
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282020_20496403478.0DomainIQ 14
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282043_20746403478.0DomainIQ 15
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282093_21246403478.0DomainIQ 16
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282116_21476403478.0DomainIQ 17
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282166_21976403478.0DomainIQ 18
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282189_22186403478.0DomainIQ 19
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282239_22706403478.0DomainIQ 20
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282262_22936403478.0DomainIQ 21
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282311_23426403478.0DomainIQ 22
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282334_23656403478.0DomainIQ 23
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282384_24156403478.0DomainIQ 24
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282407_24386403478.0DomainIQ 25
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282457_24886403478.0DomainIQ 26
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282530_25616403478.0DomainIQ 27
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282624_26536403478.0DomainIQ 28
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282665_26966403478.0DomainIQ 29
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282688_27196403478.0DomainIQ 30
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282738_27676403478.0DomainIQ 31
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282859_28906403478.0DomainIQ 32
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282909_29386403478.0DomainIQ 33
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282932_29636403478.0DomainIQ 34
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3282954_29856403478.0DomainIQ 35
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3283029_30606403478.0DomainIQ 36
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3283079_31106403478.0DomainIQ 37
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3283181_32106403478.0DomainIQ 38
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-3283204_32356403478.0DomainIQ 39
HgeneASPMchr1:197111461chr1:197009865ENST00000367409-328920_10566403478.0DomainCalponin-homology (CH) 1
TgeneF13Bchr1:197111461chr1:197008541ENST000003674121012151_210650662.0DomainSushi 3
TgeneF13Bchr1:197111461chr1:197008541ENST000003674121012211_269650662.0DomainSushi 4
TgeneF13Bchr1:197111461chr1:197008541ENST00000367412101224_88650662.0DomainSushi 1
TgeneF13Bchr1:197111461chr1:197008541ENST000003674121012272_329650662.0DomainSushi 5
TgeneF13Bchr1:197111461chr1:197008541ENST000003674121012334_391650662.0DomainSushi 6
TgeneF13Bchr1:197111461chr1:197008541ENST000003674121012394_452650662.0DomainSushi 7
TgeneF13Bchr1:197111461chr1:197008541ENST000003674121012453_516650662.0DomainSushi 8
TgeneF13Bchr1:197111461chr1:197008541ENST000003674121012522_580650662.0DomainSushi 9
TgeneF13Bchr1:197111461chr1:197008541ENST000003674121012581_647650662.0DomainSushi 10
TgeneF13Bchr1:197111461chr1:197008541ENST00000367412101289_148650662.0DomainSushi 2
TgeneF13Bchr1:197111461chr1:197009865ENST00000367412912151_210579662.0DomainSushi 3
TgeneF13Bchr1:197111461chr1:197009865ENST00000367412912211_269579662.0DomainSushi 4
TgeneF13Bchr1:197111461chr1:197009865ENST0000036741291224_88579662.0DomainSushi 1
TgeneF13Bchr1:197111461chr1:197009865ENST00000367412912272_329579662.0DomainSushi 5
TgeneF13Bchr1:197111461chr1:197009865ENST00000367412912334_391579662.0DomainSushi 6
TgeneF13Bchr1:197111461chr1:197009865ENST00000367412912394_452579662.0DomainSushi 7
TgeneF13Bchr1:197111461chr1:197009865ENST00000367412912453_516579662.0DomainSushi 8
TgeneF13Bchr1:197111461chr1:197009865ENST00000367412912522_580579662.0DomainSushi 9
TgeneF13Bchr1:197111461chr1:197009865ENST0000036741291289_148579662.0DomainSushi 2
TgeneF13Bchr1:197111461chr1:197008541ENST000003674121012617_619650662.0MotifNote=Cell attachment site


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Fusion Gene Sequence for ASPM-F13B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>7222_7222_1_ASPM-F13B_ASPM_chr1_197111461_ENST00000294732_F13B_chr1_197008541_ENST00000367412_length(transcript)=2399nt_BP=2178nt
ATTGGTGGAGGCGGCAAGTTTAAACAGAGTCAAAACGCCATACTTGTTTGGCTCCTCTTTTTAATTTGCGAGTTTATTGGGCTTGTTTTC
TGTTTTCTAGGGAGTAGGTTAGTGGAAAAGAAAAAGGGCCGAATTCACTCCCACGACCTCTACAGCCGCCCCTGAGGGGAAGCGGTCAGC
GTAAGTCCCGGATCCCCGCTCCGGAGCCGCCTCGTGGGAGCGGGGCAAGGAGATCCAGGAGGGGTCTCGAATCTGCCATGGCGAACCGGC
GAGTGGGGCGAGGCTGCTGGGAAGTGAGCCCGACCGAGCGGAGGCCGCCCGCGGGGCTGCGGGGCCCCGCGGCCGAGGAGGAGGCGTCTT
CCCCGCCGGTCCTGTCTCTCAGCCACTTCTGCAGGTCTCCTTTCCTTTGCTTCGGGGACGTTCTCCTGGGAGCCTCACGGACGCTGTCTC
TGGCCCTAGACAACCCTAACGAGGAGGTGGCAGAAGTGAAGATCTCCCACTTCCCGGCCGCGGACCTGGGCTTCAGTGTGTCGCAGCGCT
GTTTCGTGTTGCAGCCTAAAGAGAAAATTGTTATTTCTGTTAACTGGACACCACTCAAAGAAGGCCGAGTAAGAGAGATTATGACATTTC
TTGTAAATGATGTTCTGAAACACCAAGCTATATTACTAGGAAATGCAGAAGAGCAGAAAAAGAAAAAGAGGAGTCTTTGGGATACCATTA
AAAAGAAGAAAATTTCAGCCTCTACAAGTCACAACAGAAGGGTTTCAAATATTCAGAATGTTAATAAAACATTTAGTGTTTCCCAAAAAG
TTGACAGAGTTAGGAGCCCACTACAAGCTTGTGAAAACTTGGCTATGAATGAAGGCGGTCCCCCAACAGAAAACAATTCTTTAATACTTG
AAGAAAATAAAATACCCATATCACCTATTAGCCCTGCTTTCAATGAATGCCATGGTGCAACTTGCTTGCCACTCTCTGTACGTCGATCTA
CTACCTACTCATCTCTTCATGCATCAGAAAATAGGGAACTATTAAATGTACACAGTGCCAACGTTTCAAAAGTTTCTTTTAATGAGAAAG
CTGTAACTGAAACTTCCTTTAATTCCGTAAATGTTAATGGCCAAAGAGGAGAGAATAGTAAACTTAGTCTTACCCCCAACTGTTCTTCAA
CTTTGAACATTACACAAAGCCAAATACATTTTCTAAGTCCAGATTCTTTTGTAAATAATAGTCATGGAGCTAATAATGAACTAGAATTAG
TAACATGTCTTTCATCAGATATGTTTATGAAAGATAATTCACAGCCTGTGCATTTGGAATCAACAATTGCACATGAAATTTATCAGAAAA
TTTTAAGTCCAGATTCTTTCATAAAAGATAATTATGGACTAAATCAGGATCTAGAATCAGAGTCAGTTAATCCTATTTTATCCCCTAATC
AATTTTTAAAAGATAACATGGCATATATGTGTACATCTCAGCAAACATGTAAAGTACCATTATCAAATGAAAATTCTCAAGTCCCACAGT
CTCCTGAAGATTGGAGAAAAAGTGAAGTTTCGCCACGTATTCCTGAATGTCAGGGTTCAAAATCTCCCAAAGCTATTTTTGAAGAACTAG
TAGAAATGAAGTCAAATTACTACAGTTTTATAAAACAAAATAATCCTAAATTTTCTGCAGTTCAGGATATTTCTAGTCATAGCCACAATA
AACAACCTAAGAGACGTCCAATACTTTCTGCCACTGTTACTAAAAGGAAGGCCACCTGTACCAGAGAAAACCAAACTGAGATTAATAAAC
CAAAAGCAAAAAGATGTCTCAACAGTGCAGTGGGTGAACATGAAAAAGTAATAAATAATCAAAAGGAAAAAGAAGATTTTCATTCTTATC
TTCCAATTATAGATCCAATATTAAGTAAATCTAAGAGTTATAAAAACGAGGTAACACCCTCTTCGACAACAGCTTCAGTTGCTCGGAAAA
GAAAGAGCGATGGAAGCATGGAAGATGCAAATGTGAGAGTTGCAATTACAGAACATACAGAAGTGCGAGAAATCAAAAGAATCCATTTTT
CTCCCTCAGAGCCTAAAACATCAGCTGTTAAGAAAACAAAAAATGTGACAACACCCATCTCAAAACGTATTAGCAACAGAGAGAAATTAA
ACCTGAAGAAGAAAACTGCACTCTGTCTTATCAAGAACCCTTAAGAACATAGAAATGAATGGCAGAAAGAGGAGTCATATTTCAATACAT
CATGAAATTCCTTATAAAATATAATTTTGAGGAAATAAGTTAAAAACTTCGGAGTTTTTCCTTGCTTAAATATTTGAATCTAAATTATTT
GTGCTGAACATTTCGTTATTTATAAATGAAAACCAATAAATGTCTAATTTTTAGTTTGT

>7222_7222_1_ASPM-F13B_ASPM_chr1_197111461_ENST00000294732_F13B_chr1_197008541_ENST00000367412_length(amino acids)=680AA_BP=
MRGSGQRKSRIPAPEPPRGSGARRSRRGLESAMANRRVGRGCWEVSPTERRPPAGLRGPAAEEEASSPPVLSLSHFCRSPFLCFGDVLLG
ASRTLSLALDNPNEEVAEVKISHFPAADLGFSVSQRCFVLQPKEKIVISVNWTPLKEGRVREIMTFLVNDVLKHQAILLGNAEEQKKKKR
SLWDTIKKKKISASTSHNRRVSNIQNVNKTFSVSQKVDRVRSPLQACENLAMNEGGPPTENNSLILEENKIPISPISPAFNECHGATCLP
LSVRRSTTYSSLHASENRELLNVHSANVSKVSFNEKAVTETSFNSVNVNGQRGENSKLSLTPNCSSTLNITQSQIHFLSPDSFVNNSHGA
NNELELVTCLSSDMFMKDNSQPVHLESTIAHEIYQKILSPDSFIKDNYGLNQDLESESVNPILSPNQFLKDNMAYMCTSQQTCKVPLSNE
NSQVPQSPEDWRKSEVSPRIPECQGSKSPKAIFEELVEMKSNYYSFIKQNNPKFSAVQDISSHSHNKQPKRRPILSATVTKRKATCTREN
QTEINKPKAKRCLNSAVGEHEKVINNQKEKEDFHSYLPIIDPILSKSKSYKNEVTPSSTTASVARKRKSDGSMEDANVRVAITEHTEVRE
IKRIHFSPSEPKTSAVKKTKNVTTPISKRISNREKLNLKKKTALCLIKNP

--------------------------------------------------------------
>7222_7222_2_ASPM-F13B_ASPM_chr1_197111461_ENST00000294732_F13B_chr1_197009865_ENST00000367412_length(transcript)=2613nt_BP=2178nt
ATTGGTGGAGGCGGCAAGTTTAAACAGAGTCAAAACGCCATACTTGTTTGGCTCCTCTTTTTAATTTGCGAGTTTATTGGGCTTGTTTTC
TGTTTTCTAGGGAGTAGGTTAGTGGAAAAGAAAAAGGGCCGAATTCACTCCCACGACCTCTACAGCCGCCCCTGAGGGGAAGCGGTCAGC
GTAAGTCCCGGATCCCCGCTCCGGAGCCGCCTCGTGGGAGCGGGGCAAGGAGATCCAGGAGGGGTCTCGAATCTGCCATGGCGAACCGGC
GAGTGGGGCGAGGCTGCTGGGAAGTGAGCCCGACCGAGCGGAGGCCGCCCGCGGGGCTGCGGGGCCCCGCGGCCGAGGAGGAGGCGTCTT
CCCCGCCGGTCCTGTCTCTCAGCCACTTCTGCAGGTCTCCTTTCCTTTGCTTCGGGGACGTTCTCCTGGGAGCCTCACGGACGCTGTCTC
TGGCCCTAGACAACCCTAACGAGGAGGTGGCAGAAGTGAAGATCTCCCACTTCCCGGCCGCGGACCTGGGCTTCAGTGTGTCGCAGCGCT
GTTTCGTGTTGCAGCCTAAAGAGAAAATTGTTATTTCTGTTAACTGGACACCACTCAAAGAAGGCCGAGTAAGAGAGATTATGACATTTC
TTGTAAATGATGTTCTGAAACACCAAGCTATATTACTAGGAAATGCAGAAGAGCAGAAAAAGAAAAAGAGGAGTCTTTGGGATACCATTA
AAAAGAAGAAAATTTCAGCCTCTACAAGTCACAACAGAAGGGTTTCAAATATTCAGAATGTTAATAAAACATTTAGTGTTTCCCAAAAAG
TTGACAGAGTTAGGAGCCCACTACAAGCTTGTGAAAACTTGGCTATGAATGAAGGCGGTCCCCCAACAGAAAACAATTCTTTAATACTTG
AAGAAAATAAAATACCCATATCACCTATTAGCCCTGCTTTCAATGAATGCCATGGTGCAACTTGCTTGCCACTCTCTGTACGTCGATCTA
CTACCTACTCATCTCTTCATGCATCAGAAAATAGGGAACTATTAAATGTACACAGTGCCAACGTTTCAAAAGTTTCTTTTAATGAGAAAG
CTGTAACTGAAACTTCCTTTAATTCCGTAAATGTTAATGGCCAAAGAGGAGAGAATAGTAAACTTAGTCTTACCCCCAACTGTTCTTCAA
CTTTGAACATTACACAAAGCCAAATACATTTTCTAAGTCCAGATTCTTTTGTAAATAATAGTCATGGAGCTAATAATGAACTAGAATTAG
TAACATGTCTTTCATCAGATATGTTTATGAAAGATAATTCACAGCCTGTGCATTTGGAATCAACAATTGCACATGAAATTTATCAGAAAA
TTTTAAGTCCAGATTCTTTCATAAAAGATAATTATGGACTAAATCAGGATCTAGAATCAGAGTCAGTTAATCCTATTTTATCCCCTAATC
AATTTTTAAAAGATAACATGGCATATATGTGTACATCTCAGCAAACATGTAAAGTACCATTATCAAATGAAAATTCTCAAGTCCCACAGT
CTCCTGAAGATTGGAGAAAAAGTGAAGTTTCGCCACGTATTCCTGAATGTCAGGGTTCAAAATCTCCCAAAGCTATTTTTGAAGAACTAG
TAGAAATGAAGTCAAATTACTACAGTTTTATAAAACAAAATAATCCTAAATTTTCTGCAGTTCAGGATATTTCTAGTCATAGCCACAATA
AACAACCTAAGAGACGTCCAATACTTTCTGCCACTGTTACTAAAAGGAAGGCCACCTGTACCAGAGAAAACCAAACTGAGATTAATAAAC
CAAAAGCAAAAAGATGTCTCAACAGTGCAGTGGGTGAACATGAAAAAGTAATAAATAATCAAAAGGAAAAAGAAGATTTTCATTCTTATC
TTCCAATTATAGATCCAATATTAAGTAAATCTAAGAGTTATAAAAACGAGGTAACACCCTCTTCGACAACAGCTTCAGTTGCTCGGAAAA
GAAAGAGCGATGGAAGCATGGAAGATGCAAATGTGAGAGTTGCAATTACAGAACATACAGAAGTGCGAGAAATCAAAAGAATCCATTTTT
CTCCCTCAGAGCCTAAAACATCAGCTGTTAAGAAAACAAAAAATGTGACAACACCCATCTCAAAACGTATTAGCAACAGAGAGAAATTAA
ACCTGAAGAAGAAAACTGAGCCATGCACATTATCTTTTACTGAAATGGAAAAGAATAATTTACTTCTGAAATGGGATTTTGACAATAGAC
CACACATTTTGCATGGTGAATATATTGAGTTTATTTGTAGAGGAGATACTTATCCAGCTGAATTATATATTACTGGATCTATACTTAGAA
TGCAATGTGACAGAGGGCAGTTAAAATATCCAAGATGTATTCCAAGACAAAGCACTCTGTCTTATCAAGAACCCTTAAGAACATAGAAAT
GAATGGCAGAAAGAGGAGTCATATTTCAATACATCATGAAATTCCTTATAAAATATAATTTTGAGGAAATAAGTTAAAAACTTCGGAGTT
TTTCCTTGCTTAAATATTTGAATCTAAATTATTTGTGCTGAACATTTCGTTATTTATAAATGAAAACCAATAAATGTCTAATTTTTAGTT
TGT

>7222_7222_2_ASPM-F13B_ASPM_chr1_197111461_ENST00000294732_F13B_chr1_197009865_ENST00000367412_length(amino acids)=754AA_BP=1
MRGSGQRKSRIPAPEPPRGSGARRSRRGLESAMANRRVGRGCWEVSPTERRPPAGLRGPAAEEEASSPPVLSLSHFCRSPFLCFGDVLLG
ASRTLSLALDNPNEEVAEVKISHFPAADLGFSVSQRCFVLQPKEKIVISVNWTPLKEGRVREIMTFLVNDVLKHQAILLGNAEEQKKKKR
SLWDTIKKKKISASTSHNRRVSNIQNVNKTFSVSQKVDRVRSPLQACENLAMNEGGPPTENNSLILEENKIPISPISPAFNECHGATCLP
LSVRRSTTYSSLHASENRELLNVHSANVSKVSFNEKAVTETSFNSVNVNGQRGENSKLSLTPNCSSTLNITQSQIHFLSPDSFVNNSHGA
NNELELVTCLSSDMFMKDNSQPVHLESTIAHEIYQKILSPDSFIKDNYGLNQDLESESVNPILSPNQFLKDNMAYMCTSQQTCKVPLSNE
NSQVPQSPEDWRKSEVSPRIPECQGSKSPKAIFEELVEMKSNYYSFIKQNNPKFSAVQDISSHSHNKQPKRRPILSATVTKRKATCTREN
QTEINKPKAKRCLNSAVGEHEKVINNQKEKEDFHSYLPIIDPILSKSKSYKNEVTPSSTTASVARKRKSDGSMEDANVRVAITEHTEVRE
IKRIHFSPSEPKTSAVKKTKNVTTPISKRISNREKLNLKKKTEPCTLSFTEMEKNNLLLKWDFDNRPHILHGEYIEFICRGDTYPAELYI
TGSILRMQCDRGQLKYPRCIPRQSTLSYQEPLRT

--------------------------------------------------------------
>7222_7222_3_ASPM-F13B_ASPM_chr1_197111461_ENST00000367409_F13B_chr1_197008541_ENST00000367412_length(transcript)=2399nt_BP=2178nt
ATTGGTGGAGGCGGCAAGTTTAAACAGAGTCAAAACGCCATACTTGTTTGGCTCCTCTTTTTAATTTGCGAGTTTATTGGGCTTGTTTTC
TGTTTTCTAGGGAGTAGGTTAGTGGAAAAGAAAAAGGGCCGAATTCACTCCCACGACCTCTACAGCCGCCCCTGAGGGGAAGCGGTCAGC
GTAAGTCCCGGATCCCCGCTCCGGAGCCGCCTCGTGGGAGCGGGGCAAGGAGATCCAGGAGGGGTCTCGAATCTGCCATGGCGAACCGGC
GAGTGGGGCGAGGCTGCTGGGAAGTGAGCCCGACCGAGCGGAGGCCGCCCGCGGGGCTGCGGGGCCCCGCGGCCGAGGAGGAGGCGTCTT
CCCCGCCGGTCCTGTCTCTCAGCCACTTCTGCAGGTCTCCTTTCCTTTGCTTCGGGGACGTTCTCCTGGGAGCCTCACGGACGCTGTCTC
TGGCCCTAGACAACCCTAACGAGGAGGTGGCAGAAGTGAAGATCTCCCACTTCCCGGCCGCGGACCTGGGCTTCAGTGTGTCGCAGCGCT
GTTTCGTGTTGCAGCCTAAAGAGAAAATTGTTATTTCTGTTAACTGGACACCACTCAAAGAAGGCCGAGTAAGAGAGATTATGACATTTC
TTGTAAATGATGTTCTGAAACACCAAGCTATATTACTAGGAAATGCAGAAGAGCAGAAAAAGAAAAAGAGGAGTCTTTGGGATACCATTA
AAAAGAAGAAAATTTCAGCCTCTACAAGTCACAACAGAAGGGTTTCAAATATTCAGAATGTTAATAAAACATTTAGTGTTTCCCAAAAAG
TTGACAGAGTTAGGAGCCCACTACAAGCTTGTGAAAACTTGGCTATGAATGAAGGCGGTCCCCCAACAGAAAACAATTCTTTAATACTTG
AAGAAAATAAAATACCCATATCACCTATTAGCCCTGCTTTCAATGAATGCCATGGTGCAACTTGCTTGCCACTCTCTGTACGTCGATCTA
CTACCTACTCATCTCTTCATGCATCAGAAAATAGGGAACTATTAAATGTACACAGTGCCAACGTTTCAAAAGTTTCTTTTAATGAGAAAG
CTGTAACTGAAACTTCCTTTAATTCCGTAAATGTTAATGGCCAAAGAGGAGAGAATAGTAAACTTAGTCTTACCCCCAACTGTTCTTCAA
CTTTGAACATTACACAAAGCCAAATACATTTTCTAAGTCCAGATTCTTTTGTAAATAATAGTCATGGAGCTAATAATGAACTAGAATTAG
TAACATGTCTTTCATCAGATATGTTTATGAAAGATAATTCACAGCCTGTGCATTTGGAATCAACAATTGCACATGAAATTTATCAGAAAA
TTTTAAGTCCAGATTCTTTCATAAAAGATAATTATGGACTAAATCAGGATCTAGAATCAGAGTCAGTTAATCCTATTTTATCCCCTAATC
AATTTTTAAAAGATAACATGGCATATATGTGTACATCTCAGCAAACATGTAAAGTACCATTATCAAATGAAAATTCTCAAGTCCCACAGT
CTCCTGAAGATTGGAGAAAAAGTGAAGTTTCGCCACGTATTCCTGAATGTCAGGGTTCAAAATCTCCCAAAGCTATTTTTGAAGAACTAG
TAGAAATGAAGTCAAATTACTACAGTTTTATAAAACAAAATAATCCTAAATTTTCTGCAGTTCAGGATATTTCTAGTCATAGCCACAATA
AACAACCTAAGAGACGTCCAATACTTTCTGCCACTGTTACTAAAAGGAAGGCCACCTGTACCAGAGAAAACCAAACTGAGATTAATAAAC
CAAAAGCAAAAAGATGTCTCAACAGTGCAGTGGGTGAACATGAAAAAGTAATAAATAATCAAAAGGAAAAAGAAGATTTTCATTCTTATC
TTCCAATTATAGATCCAATATTAAGTAAATCTAAGAGTTATAAAAACGAGGTAACACCCTCTTCGACAACAGCTTCAGTTGCTCGGAAAA
GAAAGAGCGATGGAAGCATGGAAGATGCAAATGTGAGAGTTGCAATTACAGAACATACAGAAGTGCGAGAAATCAAAAGAATCCATTTTT
CTCCCTCAGAGCCTAAAACATCAGCTGTTAAGAAAACAAAAAATGTGACAACACCCATCTCAAAACGTATTAGCAACAGAGAGAAATTAA
ACCTGAAGAAGAAAACTGCACTCTGTCTTATCAAGAACCCTTAAGAACATAGAAATGAATGGCAGAAAGAGGAGTCATATTTCAATACAT
CATGAAATTCCTTATAAAATATAATTTTGAGGAAATAAGTTAAAAACTTCGGAGTTTTTCCTTGCTTAAATATTTGAATCTAAATTATTT
GTGCTGAACATTTCGTTATTTATAAATGAAAACCAATAAATGTCTAATTTTTAGTTTGT

>7222_7222_3_ASPM-F13B_ASPM_chr1_197111461_ENST00000367409_F13B_chr1_197008541_ENST00000367412_length(amino acids)=680AA_BP=
MRGSGQRKSRIPAPEPPRGSGARRSRRGLESAMANRRVGRGCWEVSPTERRPPAGLRGPAAEEEASSPPVLSLSHFCRSPFLCFGDVLLG
ASRTLSLALDNPNEEVAEVKISHFPAADLGFSVSQRCFVLQPKEKIVISVNWTPLKEGRVREIMTFLVNDVLKHQAILLGNAEEQKKKKR
SLWDTIKKKKISASTSHNRRVSNIQNVNKTFSVSQKVDRVRSPLQACENLAMNEGGPPTENNSLILEENKIPISPISPAFNECHGATCLP
LSVRRSTTYSSLHASENRELLNVHSANVSKVSFNEKAVTETSFNSVNVNGQRGENSKLSLTPNCSSTLNITQSQIHFLSPDSFVNNSHGA
NNELELVTCLSSDMFMKDNSQPVHLESTIAHEIYQKILSPDSFIKDNYGLNQDLESESVNPILSPNQFLKDNMAYMCTSQQTCKVPLSNE
NSQVPQSPEDWRKSEVSPRIPECQGSKSPKAIFEELVEMKSNYYSFIKQNNPKFSAVQDISSHSHNKQPKRRPILSATVTKRKATCTREN
QTEINKPKAKRCLNSAVGEHEKVINNQKEKEDFHSYLPIIDPILSKSKSYKNEVTPSSTTASVARKRKSDGSMEDANVRVAITEHTEVRE
IKRIHFSPSEPKTSAVKKTKNVTTPISKRISNREKLNLKKKTALCLIKNP

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>7222_7222_4_ASPM-F13B_ASPM_chr1_197111461_ENST00000367409_F13B_chr1_197009865_ENST00000367412_length(transcript)=2613nt_BP=2178nt
ATTGGTGGAGGCGGCAAGTTTAAACAGAGTCAAAACGCCATACTTGTTTGGCTCCTCTTTTTAATTTGCGAGTTTATTGGGCTTGTTTTC
TGTTTTCTAGGGAGTAGGTTAGTGGAAAAGAAAAAGGGCCGAATTCACTCCCACGACCTCTACAGCCGCCCCTGAGGGGAAGCGGTCAGC
GTAAGTCCCGGATCCCCGCTCCGGAGCCGCCTCGTGGGAGCGGGGCAAGGAGATCCAGGAGGGGTCTCGAATCTGCCATGGCGAACCGGC
GAGTGGGGCGAGGCTGCTGGGAAGTGAGCCCGACCGAGCGGAGGCCGCCCGCGGGGCTGCGGGGCCCCGCGGCCGAGGAGGAGGCGTCTT
CCCCGCCGGTCCTGTCTCTCAGCCACTTCTGCAGGTCTCCTTTCCTTTGCTTCGGGGACGTTCTCCTGGGAGCCTCACGGACGCTGTCTC
TGGCCCTAGACAACCCTAACGAGGAGGTGGCAGAAGTGAAGATCTCCCACTTCCCGGCCGCGGACCTGGGCTTCAGTGTGTCGCAGCGCT
GTTTCGTGTTGCAGCCTAAAGAGAAAATTGTTATTTCTGTTAACTGGACACCACTCAAAGAAGGCCGAGTAAGAGAGATTATGACATTTC
TTGTAAATGATGTTCTGAAACACCAAGCTATATTACTAGGAAATGCAGAAGAGCAGAAAAAGAAAAAGAGGAGTCTTTGGGATACCATTA
AAAAGAAGAAAATTTCAGCCTCTACAAGTCACAACAGAAGGGTTTCAAATATTCAGAATGTTAATAAAACATTTAGTGTTTCCCAAAAAG
TTGACAGAGTTAGGAGCCCACTACAAGCTTGTGAAAACTTGGCTATGAATGAAGGCGGTCCCCCAACAGAAAACAATTCTTTAATACTTG
AAGAAAATAAAATACCCATATCACCTATTAGCCCTGCTTTCAATGAATGCCATGGTGCAACTTGCTTGCCACTCTCTGTACGTCGATCTA
CTACCTACTCATCTCTTCATGCATCAGAAAATAGGGAACTATTAAATGTACACAGTGCCAACGTTTCAAAAGTTTCTTTTAATGAGAAAG
CTGTAACTGAAACTTCCTTTAATTCCGTAAATGTTAATGGCCAAAGAGGAGAGAATAGTAAACTTAGTCTTACCCCCAACTGTTCTTCAA
CTTTGAACATTACACAAAGCCAAATACATTTTCTAAGTCCAGATTCTTTTGTAAATAATAGTCATGGAGCTAATAATGAACTAGAATTAG
TAACATGTCTTTCATCAGATATGTTTATGAAAGATAATTCACAGCCTGTGCATTTGGAATCAACAATTGCACATGAAATTTATCAGAAAA
TTTTAAGTCCAGATTCTTTCATAAAAGATAATTATGGACTAAATCAGGATCTAGAATCAGAGTCAGTTAATCCTATTTTATCCCCTAATC
AATTTTTAAAAGATAACATGGCATATATGTGTACATCTCAGCAAACATGTAAAGTACCATTATCAAATGAAAATTCTCAAGTCCCACAGT
CTCCTGAAGATTGGAGAAAAAGTGAAGTTTCGCCACGTATTCCTGAATGTCAGGGTTCAAAATCTCCCAAAGCTATTTTTGAAGAACTAG
TAGAAATGAAGTCAAATTACTACAGTTTTATAAAACAAAATAATCCTAAATTTTCTGCAGTTCAGGATATTTCTAGTCATAGCCACAATA
AACAACCTAAGAGACGTCCAATACTTTCTGCCACTGTTACTAAAAGGAAGGCCACCTGTACCAGAGAAAACCAAACTGAGATTAATAAAC
CAAAAGCAAAAAGATGTCTCAACAGTGCAGTGGGTGAACATGAAAAAGTAATAAATAATCAAAAGGAAAAAGAAGATTTTCATTCTTATC
TTCCAATTATAGATCCAATATTAAGTAAATCTAAGAGTTATAAAAACGAGGTAACACCCTCTTCGACAACAGCTTCAGTTGCTCGGAAAA
GAAAGAGCGATGGAAGCATGGAAGATGCAAATGTGAGAGTTGCAATTACAGAACATACAGAAGTGCGAGAAATCAAAAGAATCCATTTTT
CTCCCTCAGAGCCTAAAACATCAGCTGTTAAGAAAACAAAAAATGTGACAACACCCATCTCAAAACGTATTAGCAACAGAGAGAAATTAA
ACCTGAAGAAGAAAACTGAGCCATGCACATTATCTTTTACTGAAATGGAAAAGAATAATTTACTTCTGAAATGGGATTTTGACAATAGAC
CACACATTTTGCATGGTGAATATATTGAGTTTATTTGTAGAGGAGATACTTATCCAGCTGAATTATATATTACTGGATCTATACTTAGAA
TGCAATGTGACAGAGGGCAGTTAAAATATCCAAGATGTATTCCAAGACAAAGCACTCTGTCTTATCAAGAACCCTTAAGAACATAGAAAT
GAATGGCAGAAAGAGGAGTCATATTTCAATACATCATGAAATTCCTTATAAAATATAATTTTGAGGAAATAAGTTAAAAACTTCGGAGTT
TTTCCTTGCTTAAATATTTGAATCTAAATTATTTGTGCTGAACATTTCGTTATTTATAAATGAAAACCAATAAATGTCTAATTTTTAGTT
TGT

>7222_7222_4_ASPM-F13B_ASPM_chr1_197111461_ENST00000367409_F13B_chr1_197009865_ENST00000367412_length(amino acids)=754AA_BP=1
MRGSGQRKSRIPAPEPPRGSGARRSRRGLESAMANRRVGRGCWEVSPTERRPPAGLRGPAAEEEASSPPVLSLSHFCRSPFLCFGDVLLG
ASRTLSLALDNPNEEVAEVKISHFPAADLGFSVSQRCFVLQPKEKIVISVNWTPLKEGRVREIMTFLVNDVLKHQAILLGNAEEQKKKKR
SLWDTIKKKKISASTSHNRRVSNIQNVNKTFSVSQKVDRVRSPLQACENLAMNEGGPPTENNSLILEENKIPISPISPAFNECHGATCLP
LSVRRSTTYSSLHASENRELLNVHSANVSKVSFNEKAVTETSFNSVNVNGQRGENSKLSLTPNCSSTLNITQSQIHFLSPDSFVNNSHGA
NNELELVTCLSSDMFMKDNSQPVHLESTIAHEIYQKILSPDSFIKDNYGLNQDLESESVNPILSPNQFLKDNMAYMCTSQQTCKVPLSNE
NSQVPQSPEDWRKSEVSPRIPECQGSKSPKAIFEELVEMKSNYYSFIKQNNPKFSAVQDISSHSHNKQPKRRPILSATVTKRKATCTREN
QTEINKPKAKRCLNSAVGEHEKVINNQKEKEDFHSYLPIIDPILSKSKSYKNEVTPSSTTASVARKRKSDGSMEDANVRVAITEHTEVRE
IKRIHFSPSEPKTSAVKKTKNVTTPISKRISNREKLNLKKKTEPCTLSFTEMEKNNLLLKWDFDNRPHILHGEYIEFICRGDTYPAELYI
TGSILRMQCDRGQLKYPRCIPRQSTLSYQEPLRT

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Fusion Gene PPI Analysis for ASPM-F13B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ASPM-F13B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneF13BP05160DB09310CatridecacogBiotechApproved
TgeneF13BP05160DB11571Human thrombinActivatorBiotechApproved
TgeneF13BP05160DB01593ZincSmall moleculeApproved|Investigational
TgeneF13BP05160DB11300ThrombinActivatorBiotechApproved|Investigational
TgeneF13BP05160DB14487Zinc acetateSmall moleculeApproved|Investigational

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Related Diseases for ASPM-F13B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneASPMC0010606Adenoid Cystic Carcinoma1CTD_human
HgeneASPMC0032460Polycystic Ovary Syndrome1CTD_human
HgeneASPMC0036095Salivary Gland Neoplasms1CTD_human
HgeneASPMC0220636Malignant neoplasm of salivary gland1CTD_human
HgeneASPMC1136382Sclerocystic Ovaries1CTD_human
HgeneASPMC1837501Microcephaly, Primary Autosomal Recessive, 51CTD_human;GENOMICS_ENGLAND
HgeneASPMC2239176Liver carcinoma1CTD_human
TgeneC2750481Factor XIII, B Subunit, Deficiency Of4CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneC0015530Hereditary Factor XIII Deficiency2CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneC0042487Venous Thrombosis1CTD_human
TgeneC0149871Deep Vein Thrombosis1CTD_human