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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SETBP1-ARNTL (FusionGDB2 ID:HG26040TG406)

Fusion Gene Summary for SETBP1-ARNTL

check button Fusion gene summary
Fusion gene informationFusion gene name: SETBP1-ARNTL
Fusion gene ID: hg26040tg406
HgeneTgene
Gene symbol

SETBP1

ARNTL

Gene ID

26040

406

Gene nameSET binding protein 1aryl hydrocarbon receptor nuclear translocator like
SynonymsMRD29|SEBBMAL1|BMAL1c|JAP3|MOP3|PASD3|TIC|bHLHe5
Cytomap('SETBP1')('ARNTL')

18q12.3

11p15.3

Type of geneprotein-codingprotein-coding
DescriptionSET-binding proteinaryl hydrocarbon receptor nuclear translocator-like protein 1ARNT-like protein 1, brain and musclePAS domain containing 3PAS domain-containing protein 3bHLH-PAS protein JAP3basic helix-loop-helix family member e5basic-helix-loop-helix-PAS orphan MOP
Modification date2020032620200322
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000282030, ENST00000426838, 
Fusion gene scores* DoF score7 X 6 X 3=1266 X 7 X 5=210
# samples 78
** MAII scorelog2(7/126*10)=-0.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/210*10)=-1.39231742277876
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SETBP1 [Title/Abstract] AND ARNTL [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSETBP1(42449248)-ARNTL(13407236), # samples:1
Anticipated loss of major functional domain due to fusion event.SETBP1-ARNTL seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
SETBP1-ARNTL seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
SETBP1-ARNTL seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
SETBP1-ARNTL seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneARNTL

GO:0032922

circadian regulation of gene expression

24005054

TgeneARNTL

GO:0045893

positive regulation of transcription, DNA-templated

11441146|12738229|23785138

TgeneARNTL

GO:0045944

positive regulation of transcription by RNA polymerase II

20093779

TgeneARNTL

GO:0051775

response to redox state

11441146


check buttonFusion gene breakpoints across SETBP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ARNTL (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCECTCGA-AJ-A3QS-01ASETBP1chr18

42449248

-ARNTLchr11

13407236

+


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Fusion Gene ORF analysis for SETBP1-ARNTL

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000282030ENST00000361003SETBP1chr18

42449248

-ARNTLchr11

13407236

+
5CDS-3UTRENST00000282030ENST00000389708SETBP1chr18

42449248

-ARNTLchr11

13407236

+
5CDS-3UTRENST00000282030ENST00000403290SETBP1chr18

42449248

-ARNTLchr11

13407236

+
5CDS-3UTRENST00000282030ENST00000403482SETBP1chr18

42449248

-ARNTLchr11

13407236

+
5CDS-3UTRENST00000282030ENST00000403510SETBP1chr18

42449248

-ARNTLchr11

13407236

+
5CDS-3UTRENST00000426838ENST00000361003SETBP1chr18

42449248

-ARNTLchr11

13407236

+
5CDS-3UTRENST00000426838ENST00000389708SETBP1chr18

42449248

-ARNTLchr11

13407236

+
5CDS-3UTRENST00000426838ENST00000403290SETBP1chr18

42449248

-ARNTLchr11

13407236

+
5CDS-3UTRENST00000426838ENST00000403482SETBP1chr18

42449248

-ARNTLchr11

13407236

+
5CDS-3UTRENST00000426838ENST00000403510SETBP1chr18

42449248

-ARNTLchr11

13407236

+
5CDS-intronENST00000282030ENST00000497429SETBP1chr18

42449248

-ARNTLchr11

13407236

+
5CDS-intronENST00000426838ENST00000497429SETBP1chr18

42449248

-ARNTLchr11

13407236

+
In-frameENST00000282030ENST00000389707SETBP1chr18

42449248

-ARNTLchr11

13407236

+
In-frameENST00000282030ENST00000396441SETBP1chr18

42449248

-ARNTLchr11

13407236

+
In-frameENST00000282030ENST00000401424SETBP1chr18

42449248

-ARNTLchr11

13407236

+
In-frameENST00000426838ENST00000389707SETBP1chr18

42449248

-ARNTLchr11

13407236

+
In-frameENST00000426838ENST00000396441SETBP1chr18

42449248

-ARNTLchr11

13407236

+
In-frameENST00000426838ENST00000401424SETBP1chr18

42449248

-ARNTLchr11

13407236

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000426838SETBP1chr1842449248-ENST00000396441ARNTLchr1113407236+17049353951198267
ENST00000426838SETBP1chr1842449248-ENST00000389707ARNTLchr1113407236+17099353951198267
ENST00000426838SETBP1chr1842449248-ENST00000401424ARNTLchr1113407236+17099353951198267
ENST00000282030SETBP1chr1842449248-ENST00000396441ARNTLchr1113407236+16058362961099267
ENST00000282030SETBP1chr1842449248-ENST00000389707ARNTLchr1113407236+16108362961099267
ENST00000282030SETBP1chr1842449248-ENST00000401424ARNTLchr1113407236+16108362961099267

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000426838ENST00000396441SETBP1chr1842449248-ARNTLchr1113407236+0.0010063520.9989937
ENST00000426838ENST00000389707SETBP1chr1842449248-ARNTLchr1113407236+0.00101210.99898785
ENST00000426838ENST00000401424SETBP1chr1842449248-ARNTLchr1113407236+0.00101210.99898785
ENST00000282030ENST00000396441SETBP1chr1842449248-ARNTLchr1113407236+0.0009836280.9990164
ENST00000282030ENST00000389707SETBP1chr1842449248-ARNTLchr1113407236+0.0009772780.9990227
ENST00000282030ENST00000401424SETBP1chr1842449248-ARNTLchr1113407236+0.0009772780.9990227

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Fusion Genomic Features for SETBP1-ARNTL


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for SETBP1-ARNTL


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:42449248/chr11:13407236)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSETBP1chr18:42449248chr11:13407236ENST00000282030-361016_10281801597.0DNA bindingNote=A.T hook 2
HgeneSETBP1chr18:42449248chr11:13407236ENST00000282030-361451_14631801597.0DNA bindingNote=A.T hook 3
HgeneSETBP1chr18:42449248chr11:13407236ENST00000282030-36584_5961801597.0DNA bindingNote=A.T hook 1
HgeneSETBP1chr18:42449248chr11:13407236ENST00000426838-341016_1028180243.0DNA bindingNote=A.T hook 2
HgeneSETBP1chr18:42449248chr11:13407236ENST00000426838-341451_1463180243.0DNA bindingNote=A.T hook 3
HgeneSETBP1chr18:42449248chr11:13407236ENST00000426838-34584_596180243.0DNA bindingNote=A.T hook 1
HgeneSETBP1chr18:42449248chr11:13407236ENST00000282030-361520_15431801597.0RegionNote=3 X 8 AA tandem repeats of P-P-L-P-P-P-P-P
HgeneSETBP1chr18:42449248chr11:13407236ENST00000426838-341520_1543180243.0RegionNote=3 X 8 AA tandem repeats of P-P-L-P-P-P-P-P
HgeneSETBP1chr18:42449248chr11:13407236ENST00000282030-361520_15271801597.0RepeatNote=1
HgeneSETBP1chr18:42449248chr11:13407236ENST00000282030-361528_15351801597.0RepeatNote=2
HgeneSETBP1chr18:42449248chr11:13407236ENST00000282030-361536_15431801597.0RepeatNote=3
HgeneSETBP1chr18:42449248chr11:13407236ENST00000426838-341520_1527180243.0RepeatNote=1
HgeneSETBP1chr18:42449248chr11:13407236ENST00000426838-341528_1535180243.0RepeatNote=2
HgeneSETBP1chr18:42449248chr11:13407236ENST00000426838-341536_1543180243.0RepeatNote=3
TgeneARNTLchr18:42449248chr11:13407236ENST000003610031518143_215421509.0DomainPAS 1
TgeneARNTLchr18:42449248chr11:13407236ENST000003610031518326_396421509.0DomainPAS 2
TgeneARNTLchr18:42449248chr11:13407236ENST000003610031518401_444421509.0DomainNote=PAC
TgeneARNTLchr18:42449248chr11:13407236ENST00000361003151872_125421509.0DomainbHLH
TgeneARNTLchr18:42449248chr11:13407236ENST000003897071720143_215538626.0DomainPAS 1
TgeneARNTLchr18:42449248chr11:13407236ENST000003897071720326_396538626.0DomainPAS 2
TgeneARNTLchr18:42449248chr11:13407236ENST000003897071720401_444538626.0DomainNote=PAC
TgeneARNTLchr18:42449248chr11:13407236ENST00000389707172072_125538626.0DomainbHLH
TgeneARNTLchr18:42449248chr11:13407236ENST000003964411619143_215538626.0DomainPAS 1
TgeneARNTLchr18:42449248chr11:13407236ENST000003964411619326_396538626.0DomainPAS 2
TgeneARNTLchr18:42449248chr11:13407236ENST000003964411619401_444538626.0DomainNote=PAC
TgeneARNTLchr18:42449248chr11:13407236ENST00000396441161972_125538626.0DomainbHLH
TgeneARNTLchr18:42449248chr11:13407236ENST000004014241720143_215496584.0DomainPAS 1
TgeneARNTLchr18:42449248chr11:13407236ENST000004014241720326_396496584.0DomainPAS 2
TgeneARNTLchr18:42449248chr11:13407236ENST000004014241720401_444496584.0DomainNote=PAC
TgeneARNTLchr18:42449248chr11:13407236ENST00000401424172072_125496584.0DomainbHLH
TgeneARNTLchr18:42449248chr11:13407236ENST000004032901720143_215539627.0DomainPAS 1
TgeneARNTLchr18:42449248chr11:13407236ENST000004032901720326_396539627.0DomainPAS 2
TgeneARNTLchr18:42449248chr11:13407236ENST000004032901720401_444539627.0DomainNote=PAC
TgeneARNTLchr18:42449248chr11:13407236ENST00000403290172072_125539627.0DomainbHLH
TgeneARNTLchr18:42449248chr11:13407236ENST000004034821114143_215537625.0DomainPAS 1
TgeneARNTLchr18:42449248chr11:13407236ENST000004034821114326_396537625.0DomainPAS 2
TgeneARNTLchr18:42449248chr11:13407236ENST000004034821114401_444537625.0DomainNote=PAC
TgeneARNTLchr18:42449248chr11:13407236ENST00000403482111472_125537625.0DomainbHLH
TgeneARNTLchr18:42449248chr11:13407236ENST000004035101720143_215495583.0DomainPAS 1
TgeneARNTLchr18:42449248chr11:13407236ENST000004035101720326_396495583.0DomainPAS 2
TgeneARNTLchr18:42449248chr11:13407236ENST000004035101720401_444495583.0DomainNote=PAC
TgeneARNTLchr18:42449248chr11:13407236ENST00000403510172072_125495583.0DomainbHLH
TgeneARNTLchr18:42449248chr11:13407236ENST000003610031518142_152421509.0MotifNuclear export signal 1
TgeneARNTLchr18:42449248chr11:13407236ENST000003610031518361_369421509.0MotifNuclear export signal 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000361003151836_41421509.0MotifNuclear localization signal
TgeneARNTLchr18:42449248chr11:13407236ENST000003897071720142_152538626.0MotifNuclear export signal 1
TgeneARNTLchr18:42449248chr11:13407236ENST000003897071720361_369538626.0MotifNuclear export signal 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000389707172036_41538626.0MotifNuclear localization signal
TgeneARNTLchr18:42449248chr11:13407236ENST000003964411619142_152538626.0MotifNuclear export signal 1
TgeneARNTLchr18:42449248chr11:13407236ENST000003964411619361_369538626.0MotifNuclear export signal 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000396441161936_41538626.0MotifNuclear localization signal
TgeneARNTLchr18:42449248chr11:13407236ENST000004014241720142_152496584.0MotifNuclear export signal 1
TgeneARNTLchr18:42449248chr11:13407236ENST000004014241720361_369496584.0MotifNuclear export signal 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000401424172036_41496584.0MotifNuclear localization signal
TgeneARNTLchr18:42449248chr11:13407236ENST000004032901720142_152539627.0MotifNuclear export signal 1
TgeneARNTLchr18:42449248chr11:13407236ENST000004032901720361_369539627.0MotifNuclear export signal 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000403290172036_41539627.0MotifNuclear localization signal
TgeneARNTLchr18:42449248chr11:13407236ENST000004034821114142_152537625.0MotifNuclear export signal 1
TgeneARNTLchr18:42449248chr11:13407236ENST000004034821114361_369537625.0MotifNuclear export signal 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000403482111436_41537625.0MotifNuclear localization signal
TgeneARNTLchr18:42449248chr11:13407236ENST000004035101720142_152495583.0MotifNuclear export signal 1
TgeneARNTLchr18:42449248chr11:13407236ENST000004035101720361_369495583.0MotifNuclear export signal 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000403510172036_41495583.0MotifNuclear localization signal


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Fusion Gene Sequence for SETBP1-ARNTL


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>80849_80849_1_SETBP1-ARNTL_SETBP1_chr18_42449248_ENST00000282030_ARNTL_chr11_13407236_ENST00000389707_length(transcript)=1610nt_BP=836nt
GGTTAAGTGGAGCTAGAGAGCTACATTGTAACCTAGTTGGATTTTTTTGGGGGGGGAATGTATCAGAATCTAACGTGTCGTTAATAGAAA
GAAGAACAGGCAAGAAGTGGTCCAGCCGGCGAAGTTGCAGATCTGATCTCTTCTGAACACCTCATCGTGTCTCCATCCCTGGGAATCTGA
CCCTAGCAACTGGACCACTTTGTTCTTGGAATTTTGGGTGTCCTCTTTTCTCACCTTTCCCTTTTCCCTTTTCCCCTTCCCCCTCCTGAG
AACTCCGGAAGACTGTAGAGATTGTCATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACTTCCTGCCGG
TCTCCTCAGCCAAGCCCCCAGCTGCTCCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCCCGGTGGGCG
GAGAGCGCATGGAGCCAGAGGAGGAGGATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGAAATGGGTGG
CAGGAGATGGTTTGGAAGAGCAGGAATTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGACCACAAAGC
GGGCTAAGAAACCCCCAAAGAATTTGGAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACCAGAAGGTGT
CCCGTGCTGGAAAAAATAGCAAAGCCACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACCTTGCAGCCA
GTGACCTCAAAGGATTTCAGCCACAGATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGGCTCAGGAGA
ACCCAGGTTATCCATATTCTGATAGTTCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACCAAGGATCAA
GTAGTCCCAGTAATGATGAGGCAGCAATGGCTGTCATCATGAGCCTCTTGGAAGCAGATGCTGGACTGGGTGGCCCTGTTGACTTTAGTG
ACTTGCCATGGCCGCTGTAAACACTACATGTTGCTTTGGCAACAGCTATAGTATCAAAGTGCATTACTGGTGGAGTTTTACAGTCTGTGA
AGCTTACTGGATAAGGAGAGAATAGCTTTTATGTACTGACTTCATAAAAGCCATCTCAGAGCCATTGATACAAGTCAATCTTACTATATG
TAACTTCAGACAAAGTGGAACTAAGCCTGCTCCAGTGTTTCCTCATCATTGATTATTGGGCTAGCTGTGGATAGCTTGCATTAATTGTAT
ATTTTGGATTCTGTTTGTGTTGAATTTTTTAATCATTGTGCACAGAAGCATCATTGGTAGCTTTTATATGCAAATGGTCATTTCAGATGT
ATGGTGTTTTTACACTACAAAGAAGTCCCCCATGTGGATATTTCTTATACTAATTGTATCATAAAGCCGTTTATTCTTCCTTGTAAGAAT

>80849_80849_1_SETBP1-ARNTL_SETBP1_chr18_42449248_ENST00000282030_ARNTL_chr11_13407236_ENST00000389707_length(amino acids)=267AA_BP=180
MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEEQE
FSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ

--------------------------------------------------------------
>80849_80849_2_SETBP1-ARNTL_SETBP1_chr18_42449248_ENST00000282030_ARNTL_chr11_13407236_ENST00000396441_length(transcript)=1605nt_BP=836nt
GGTTAAGTGGAGCTAGAGAGCTACATTGTAACCTAGTTGGATTTTTTTGGGGGGGGAATGTATCAGAATCTAACGTGTCGTTAATAGAAA
GAAGAACAGGCAAGAAGTGGTCCAGCCGGCGAAGTTGCAGATCTGATCTCTTCTGAACACCTCATCGTGTCTCCATCCCTGGGAATCTGA
CCCTAGCAACTGGACCACTTTGTTCTTGGAATTTTGGGTGTCCTCTTTTCTCACCTTTCCCTTTTCCCTTTTCCCCTTCCCCCTCCTGAG
AACTCCGGAAGACTGTAGAGATTGTCATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACTTCCTGCCGG
TCTCCTCAGCCAAGCCCCCAGCTGCTCCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCCCGGTGGGCG
GAGAGCGCATGGAGCCAGAGGAGGAGGATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGAAATGGGTGG
CAGGAGATGGTTTGGAAGAGCAGGAATTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGACCACAAAGC
GGGCTAAGAAACCCCCAAAGAATTTGGAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACCAGAAGGTGT
CCCGTGCTGGAAAAAATAGCAAAGCCACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACCTTGCAGCCA
GTGACCTCAAAGGATTTCAGCCACAGATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGGCTCAGGAGA
ACCCAGGTTATCCATATTCTGATAGTTCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACCAAGGATCAA
GTAGTCCCAGTAATGATGAGGCAGCAATGGCTGTCATCATGAGCCTCTTGGAAGCAGATGCTGGACTGGGTGGCCCTGTTGACTTTAGTG
ACTTGCCATGGCCGCTGTAAACACTACATGTTGCTTTGGCAACAGCTATAGTATCAAAGTGCATTACTGGTGGAGTTTTACAGTCTGTGA
AGCTTACTGGATAAGGAGAGAATAGCTTTTATGTACTGACTTCATAAAAGCCATCTCAGAGCCATTGATACAAGTCAATCTTACTATATG
TAACTTCAGACAAAGTGGAACTAAGCCTGCTCCAGTGTTTCCTCATCATTGATTATTGGGCTAGCTGTGGATAGCTTGCATTAATTGTAT
ATTTTGGATTCTGTTTGTGTTGAATTTTTTAATCATTGTGCACAGAAGCATCATTGGTAGCTTTTATATGCAAATGGTCATTTCAGATGT
ATGGTGTTTTTACACTACAAAGAAGTCCCCCATGTGGATATTTCTTATACTAATTGTATCATAAAGCCGTTTATTCTTCCTTGTAAGAAT

>80849_80849_2_SETBP1-ARNTL_SETBP1_chr18_42449248_ENST00000282030_ARNTL_chr11_13407236_ENST00000396441_length(amino acids)=267AA_BP=180
MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEEQE
FSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ

--------------------------------------------------------------
>80849_80849_3_SETBP1-ARNTL_SETBP1_chr18_42449248_ENST00000282030_ARNTL_chr11_13407236_ENST00000401424_length(transcript)=1610nt_BP=836nt
GGTTAAGTGGAGCTAGAGAGCTACATTGTAACCTAGTTGGATTTTTTTGGGGGGGGAATGTATCAGAATCTAACGTGTCGTTAATAGAAA
GAAGAACAGGCAAGAAGTGGTCCAGCCGGCGAAGTTGCAGATCTGATCTCTTCTGAACACCTCATCGTGTCTCCATCCCTGGGAATCTGA
CCCTAGCAACTGGACCACTTTGTTCTTGGAATTTTGGGTGTCCTCTTTTCTCACCTTTCCCTTTTCCCTTTTCCCCTTCCCCCTCCTGAG
AACTCCGGAAGACTGTAGAGATTGTCATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACTTCCTGCCGG
TCTCCTCAGCCAAGCCCCCAGCTGCTCCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCCCGGTGGGCG
GAGAGCGCATGGAGCCAGAGGAGGAGGATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGAAATGGGTGG
CAGGAGATGGTTTGGAAGAGCAGGAATTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGACCACAAAGC
GGGCTAAGAAACCCCCAAAGAATTTGGAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACCAGAAGGTGT
CCCGTGCTGGAAAAAATAGCAAAGCCACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACCTTGCAGCCA
GTGACCTCAAAGGATTTCAGCCACAGATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGGCTCAGGAGA
ACCCAGGTTATCCATATTCTGATAGTTCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACCAAGGATCAA
GTAGTCCCAGTAATGATGAGGCAGCAATGGCTGTCATCATGAGCCTCTTGGAAGCAGATGCTGGACTGGGTGGCCCTGTTGACTTTAGTG
ACTTGCCATGGCCGCTGTAAACACTACATGTTGCTTTGGCAACAGCTATAGTATCAAAGTGCATTACTGGTGGAGTTTTACAGTCTGTGA
AGCTTACTGGATAAGGAGAGAATAGCTTTTATGTACTGACTTCATAAAAGCCATCTCAGAGCCATTGATACAAGTCAATCTTACTATATG
TAACTTCAGACAAAGTGGAACTAAGCCTGCTCCAGTGTTTCCTCATCATTGATTATTGGGCTAGCTGTGGATAGCTTGCATTAATTGTAT
ATTTTGGATTCTGTTTGTGTTGAATTTTTTAATCATTGTGCACAGAAGCATCATTGGTAGCTTTTATATGCAAATGGTCATTTCAGATGT
ATGGTGTTTTTACACTACAAAGAAGTCCCCCATGTGGATATTTCTTATACTAATTGTATCATAAAGCCGTTTATTCTTCCTTGTAAGAAT

>80849_80849_3_SETBP1-ARNTL_SETBP1_chr18_42449248_ENST00000282030_ARNTL_chr11_13407236_ENST00000401424_length(amino acids)=267AA_BP=180
MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEEQE
FSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ

--------------------------------------------------------------
>80849_80849_4_SETBP1-ARNTL_SETBP1_chr18_42449248_ENST00000426838_ARNTL_chr11_13407236_ENST00000389707_length(transcript)=1709nt_BP=935nt
AAGCGCGGGGCCGGCCGGGGCGCCCGCCGCTCGCCGCCGCCTCCGCGCGCCCGGGGGCCCCGGCGCCCCCCGAGCTAGGGCGGCCAGCTC
GCGGCTCGCCGTTTGACAGATGCTCATCGCCATGGAGTTGCCGCAGCAGCACCTTTGGGGGCTCGGGCGAGCGACGGGAGCCGGGATCTG
AGCGAGCGCCGGGGCCAGCGGAGCCGGAGCCGCCGGGACATGGTTGCAGATCTGATCTCTTCTGAACACCTCATCGTGTCTCCATCCCTG
GGAATCTGACCCTAGCAACTGGACCACTTTGTTCTTGGAATTTTGGGTGTCCTCTTTTCTCACCTTTCCCTTTTCCCTTTTCCCCTTCCC
CCTCCTGAGAACTCCGGAAGACTGTAGAGATTGTCATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACT
TCCTGCCGGTCTCCTCAGCCAAGCCCCCAGCTGCTCCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCC
CGGTGGGCGGAGAGCGCATGGAGCCAGAGGAGGAGGATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGA
AATGGGTGGCAGGAGATGGTTTGGAAGAGCAGGAATTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGA
CCACAAAGCGGGCTAAGAAACCCCCAAAGAATTTGGAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACC
AGAAGGTGTCCCGTGCTGGAAAAAATAGCAAAGCCACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACC
TTGCAGCCAGTGACCTCAAAGGATTTCAGCCACAGATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGG
CTCAGGAGAACCCAGGTTATCCATATTCTGATAGTTCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACC
AAGGATCAAGTAGTCCCAGTAATGATGAGGCAGCAATGGCTGTCATCATGAGCCTCTTGGAAGCAGATGCTGGACTGGGTGGCCCTGTTG
ACTTTAGTGACTTGCCATGGCCGCTGTAAACACTACATGTTGCTTTGGCAACAGCTATAGTATCAAAGTGCATTACTGGTGGAGTTTTAC
AGTCTGTGAAGCTTACTGGATAAGGAGAGAATAGCTTTTATGTACTGACTTCATAAAAGCCATCTCAGAGCCATTGATACAAGTCAATCT
TACTATATGTAACTTCAGACAAAGTGGAACTAAGCCTGCTCCAGTGTTTCCTCATCATTGATTATTGGGCTAGCTGTGGATAGCTTGCAT
TAATTGTATATTTTGGATTCTGTTTGTGTTGAATTTTTTAATCATTGTGCACAGAAGCATCATTGGTAGCTTTTATATGCAAATGGTCAT
TTCAGATGTATGGTGTTTTTACACTACAAAGAAGTCCCCCATGTGGATATTTCTTATACTAATTGTATCATAAAGCCGTTTATTCTTCCT

>80849_80849_4_SETBP1-ARNTL_SETBP1_chr18_42449248_ENST00000426838_ARNTL_chr11_13407236_ENST00000389707_length(amino acids)=267AA_BP=180
MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEEQE
FSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ

--------------------------------------------------------------
>80849_80849_5_SETBP1-ARNTL_SETBP1_chr18_42449248_ENST00000426838_ARNTL_chr11_13407236_ENST00000396441_length(transcript)=1704nt_BP=935nt
AAGCGCGGGGCCGGCCGGGGCGCCCGCCGCTCGCCGCCGCCTCCGCGCGCCCGGGGGCCCCGGCGCCCCCCGAGCTAGGGCGGCCAGCTC
GCGGCTCGCCGTTTGACAGATGCTCATCGCCATGGAGTTGCCGCAGCAGCACCTTTGGGGGCTCGGGCGAGCGACGGGAGCCGGGATCTG
AGCGAGCGCCGGGGCCAGCGGAGCCGGAGCCGCCGGGACATGGTTGCAGATCTGATCTCTTCTGAACACCTCATCGTGTCTCCATCCCTG
GGAATCTGACCCTAGCAACTGGACCACTTTGTTCTTGGAATTTTGGGTGTCCTCTTTTCTCACCTTTCCCTTTTCCCTTTTCCCCTTCCC
CCTCCTGAGAACTCCGGAAGACTGTAGAGATTGTCATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACT
TCCTGCCGGTCTCCTCAGCCAAGCCCCCAGCTGCTCCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCC
CGGTGGGCGGAGAGCGCATGGAGCCAGAGGAGGAGGATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGA
AATGGGTGGCAGGAGATGGTTTGGAAGAGCAGGAATTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGA
CCACAAAGCGGGCTAAGAAACCCCCAAAGAATTTGGAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACC
AGAAGGTGTCCCGTGCTGGAAAAAATAGCAAAGCCACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACC
TTGCAGCCAGTGACCTCAAAGGATTTCAGCCACAGATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGG
CTCAGGAGAACCCAGGTTATCCATATTCTGATAGTTCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACC
AAGGATCAAGTAGTCCCAGTAATGATGAGGCAGCAATGGCTGTCATCATGAGCCTCTTGGAAGCAGATGCTGGACTGGGTGGCCCTGTTG
ACTTTAGTGACTTGCCATGGCCGCTGTAAACACTACATGTTGCTTTGGCAACAGCTATAGTATCAAAGTGCATTACTGGTGGAGTTTTAC
AGTCTGTGAAGCTTACTGGATAAGGAGAGAATAGCTTTTATGTACTGACTTCATAAAAGCCATCTCAGAGCCATTGATACAAGTCAATCT
TACTATATGTAACTTCAGACAAAGTGGAACTAAGCCTGCTCCAGTGTTTCCTCATCATTGATTATTGGGCTAGCTGTGGATAGCTTGCAT
TAATTGTATATTTTGGATTCTGTTTGTGTTGAATTTTTTAATCATTGTGCACAGAAGCATCATTGGTAGCTTTTATATGCAAATGGTCAT
TTCAGATGTATGGTGTTTTTACACTACAAAGAAGTCCCCCATGTGGATATTTCTTATACTAATTGTATCATAAAGCCGTTTATTCTTCCT

>80849_80849_5_SETBP1-ARNTL_SETBP1_chr18_42449248_ENST00000426838_ARNTL_chr11_13407236_ENST00000396441_length(amino acids)=267AA_BP=180
MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEEQE
FSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ

--------------------------------------------------------------
>80849_80849_6_SETBP1-ARNTL_SETBP1_chr18_42449248_ENST00000426838_ARNTL_chr11_13407236_ENST00000401424_length(transcript)=1709nt_BP=935nt
AAGCGCGGGGCCGGCCGGGGCGCCCGCCGCTCGCCGCCGCCTCCGCGCGCCCGGGGGCCCCGGCGCCCCCCGAGCTAGGGCGGCCAGCTC
GCGGCTCGCCGTTTGACAGATGCTCATCGCCATGGAGTTGCCGCAGCAGCACCTTTGGGGGCTCGGGCGAGCGACGGGAGCCGGGATCTG
AGCGAGCGCCGGGGCCAGCGGAGCCGGAGCCGCCGGGACATGGTTGCAGATCTGATCTCTTCTGAACACCTCATCGTGTCTCCATCCCTG
GGAATCTGACCCTAGCAACTGGACCACTTTGTTCTTGGAATTTTGGGTGTCCTCTTTTCTCACCTTTCCCTTTTCCCTTTTCCCCTTCCC
CCTCCTGAGAACTCCGGAAGACTGTAGAGATTGTCATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACT
TCCTGCCGGTCTCCTCAGCCAAGCCCCCAGCTGCTCCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCC
CGGTGGGCGGAGAGCGCATGGAGCCAGAGGAGGAGGATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGA
AATGGGTGGCAGGAGATGGTTTGGAAGAGCAGGAATTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGA
CCACAAAGCGGGCTAAGAAACCCCCAAAGAATTTGGAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACC
AGAAGGTGTCCCGTGCTGGAAAAAATAGCAAAGCCACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACC
TTGCAGCCAGTGACCTCAAAGGATTTCAGCCACAGATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGG
CTCAGGAGAACCCAGGTTATCCATATTCTGATAGTTCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACC
AAGGATCAAGTAGTCCCAGTAATGATGAGGCAGCAATGGCTGTCATCATGAGCCTCTTGGAAGCAGATGCTGGACTGGGTGGCCCTGTTG
ACTTTAGTGACTTGCCATGGCCGCTGTAAACACTACATGTTGCTTTGGCAACAGCTATAGTATCAAAGTGCATTACTGGTGGAGTTTTAC
AGTCTGTGAAGCTTACTGGATAAGGAGAGAATAGCTTTTATGTACTGACTTCATAAAAGCCATCTCAGAGCCATTGATACAAGTCAATCT
TACTATATGTAACTTCAGACAAAGTGGAACTAAGCCTGCTCCAGTGTTTCCTCATCATTGATTATTGGGCTAGCTGTGGATAGCTTGCAT
TAATTGTATATTTTGGATTCTGTTTGTGTTGAATTTTTTAATCATTGTGCACAGAAGCATCATTGGTAGCTTTTATATGCAAATGGTCAT
TTCAGATGTATGGTGTTTTTACACTACAAAGAAGTCCCCCATGTGGATATTTCTTATACTAATTGTATCATAAAGCCGTTTATTCTTCCT

>80849_80849_6_SETBP1-ARNTL_SETBP1_chr18_42449248_ENST00000426838_ARNTL_chr11_13407236_ENST00000401424_length(amino acids)=267AA_BP=180
MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEEQE
FSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SETBP1-ARNTL


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneARNTLchr18:42449248chr11:13407236ENST000003610031518508_588421.0509.0CIART
TgeneARNTLchr18:42449248chr11:13407236ENST000004014241720508_588496.0584.0CIART
TgeneARNTLchr18:42449248chr11:13407236ENST000004035101720508_588495.0583.0CIART


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneARNTLchr18:42449248chr11:13407236ENST000003897071720508_588538.0626.0CIART
TgeneARNTLchr18:42449248chr11:13407236ENST000003964411619508_588538.0626.0CIART
TgeneARNTLchr18:42449248chr11:13407236ENST000004032901720508_588539.0627.0CIART
TgeneARNTLchr18:42449248chr11:13407236ENST000004034821114508_588537.0625.0CIART


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SETBP1-ARNTL


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SETBP1-ARNTL


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSETBP1C0265227Schinzel-Giedion syndrome4CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneSETBP1C0020796Profound Mental Retardation2CTD_human
HgeneSETBP1C0023467Leukemia, Myelocytic, Acute2CGI;UNIPROT
HgeneSETBP1C0025363Mental Retardation, Psychosocial2CTD_human
HgeneSETBP1C0349639Juvenile Myelomonocytic Leukemia2CTD_human;UNIPROT
HgeneSETBP1C0917816Mental deficiency2CTD_human
HgeneSETBP1C3463824MYELODYSPLASTIC SYNDROME2CGI;UNIPROT
HgeneSETBP1C3714756Intellectual Disability2CTD_human
HgeneSETBP1C0000772Multiple congenital anomalies1CTD_human
HgeneSETBP1C0006142Malignant neoplasm of breast1CTD_human
HgeneSETBP1C0023012Language Delay1CTD_human
HgeneSETBP1C0023014Language Development Disorders1CTD_human
HgeneSETBP1C0023466Leukemia, Monocytic, Chronic1CTD_human
HgeneSETBP1C0023470Myeloid Leukemia1CTD_human
HgeneSETBP1C0023473Myeloid Leukemia, Chronic1CGI;UNIPROT
HgeneSETBP1C0043094Weight Gain1CTD_human
HgeneSETBP1C0241210Speech Delay1CTD_human
HgeneSETBP1C0376634Craniofacial Abnormalities1CTD_human
HgeneSETBP1C0454655Semantic-Pragmatic Disorder1CTD_human
HgeneSETBP1C0678222Breast Carcinoma1CTD_human
HgeneSETBP1C0751257Auditory Processing Disorder, Central1CTD_human
HgeneSETBP1C1257931Mammary Neoplasms, Human1CTD_human
HgeneSETBP1C1292772Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative1CGI;CTD_human
HgeneSETBP1C1458155Mammary Neoplasms1CTD_human
HgeneSETBP1C1535926Neurodevelopmental Disorders1CTD_human
HgeneSETBP1C4704874Mammary Carcinoma, Human1CTD_human
TgeneC0005586Bipolar Disorder5PSYGENET
TgeneC0011570Mental Depression3PSYGENET
TgeneC0011581Depressive disorder3PSYGENET
TgeneC0525045Mood Disorders2PSYGENET
TgeneC0000772Multiple congenital anomalies1CTD_human
TgeneC0021361Female infertility1CTD_human
TgeneC0023473Myeloid Leukemia, Chronic1CTD_human
TgeneC0038279Sterility, Postpartum1CTD_human
TgeneC0085159Seasonal Affective Disorder1PSYGENET
TgeneC0151744Myocardial Ischemia1CTD_human
TgeneC0268548Hyperargininemia1CTD_human
TgeneC0341869Subfertility, Female1CTD_human
TgeneC0917730Female sterility1CTD_human