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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:C12orf36-KANK2 (FusionGDB2 ID:HG283422TG25959)

Fusion Gene Summary for C12orf36-KANK2

check button Fusion gene summary
Fusion gene informationFusion gene name: C12orf36-KANK2
Fusion gene ID: hg283422tg25959
HgeneTgene
Gene symbol

C12orf36

KANK2

Gene ID

283422

25959

Gene namelong intergenic non-protein coding RNA 1559KN motif and ankyrin repeat domains 2
SynonymsC12orf36ANKRD25|MXRA3|NPHS16|PPKWH|SIP
Cytomap('C12orf36')('KANK2')

12p13.1

19p13.2

Type of genencRNAprotein-coding
Description-KN motif and ankyrin repeat domain-containing protein 2SRC-interacting proteinSRC1-interacting proteinankyrin repeat domain-containing protein 25kidney ankyrin repeat-containing protein 2matrix-remodeling-associated protein 3
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000318426, ENST00000527705, 
ENST00000531049, ENST00000539026, 
ENST00000532841, 
Fusion gene scores* DoF score4 X 3 X 2=244 X 3 X 3=36
# samples 24
** MAII scorelog2(2/24*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: C12orf36 [Title/Abstract] AND KANK2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointC12orf36(13529157)-KANK2(11289396), # samples:1
Anticipated loss of major functional domain due to fusion event.C12orf36-KANK2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
C12orf36-KANK2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
C12orf36-KANK2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
C12orf36-KANK2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
C12orf36-KANK2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneKANK2

GO:0000122

negative regulation of transcription by RNA polymerase II

17476305

TgeneKANK2

GO:0008285

negative regulation of cell proliferation

17476305

TgeneKANK2

GO:0033147

negative regulation of intracellular estrogen receptor signaling pathway

17476305

TgeneKANK2

GO:0043069

negative regulation of programmed cell death

22371500

TgeneKANK2

GO:2000134

negative regulation of G1/S transition of mitotic cell cycle

17476305


check buttonFusion gene breakpoints across C12orf36 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across KANK2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-A4J5C12orf36chr12

13529157

-KANK2chr19

11289396

-


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Fusion Gene ORF analysis for C12orf36-KANK2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000318426ENST00000587317C12orf36chr12

13529157

-KANK2chr19

11289396

-
5CDS-intronENST00000318426ENST00000589359C12orf36chr12

13529157

-KANK2chr19

11289396

-
5CDS-intronENST00000318426ENST00000589894C12orf36chr12

13529157

-KANK2chr19

11289396

-
5CDS-intronENST00000527705ENST00000587317C12orf36chr12

13529157

-KANK2chr19

11289396

-
5CDS-intronENST00000527705ENST00000589359C12orf36chr12

13529157

-KANK2chr19

11289396

-
5CDS-intronENST00000527705ENST00000589894C12orf36chr12

13529157

-KANK2chr19

11289396

-
5CDS-intronENST00000531049ENST00000587317C12orf36chr12

13529157

-KANK2chr19

11289396

-
5CDS-intronENST00000531049ENST00000589359C12orf36chr12

13529157

-KANK2chr19

11289396

-
5CDS-intronENST00000531049ENST00000589894C12orf36chr12

13529157

-KANK2chr19

11289396

-
5CDS-intronENST00000539026ENST00000587317C12orf36chr12

13529157

-KANK2chr19

11289396

-
5CDS-intronENST00000539026ENST00000589359C12orf36chr12

13529157

-KANK2chr19

11289396

-
5CDS-intronENST00000539026ENST00000589894C12orf36chr12

13529157

-KANK2chr19

11289396

-
Frame-shiftENST00000527705ENST00000355150C12orf36chr12

13529157

-KANK2chr19

11289396

-
Frame-shiftENST00000527705ENST00000432929C12orf36chr12

13529157

-KANK2chr19

11289396

-
Frame-shiftENST00000527705ENST00000586659C12orf36chr12

13529157

-KANK2chr19

11289396

-
In-frameENST00000318426ENST00000355150C12orf36chr12

13529157

-KANK2chr19

11289396

-
In-frameENST00000318426ENST00000432929C12orf36chr12

13529157

-KANK2chr19

11289396

-
In-frameENST00000318426ENST00000586659C12orf36chr12

13529157

-KANK2chr19

11289396

-
In-frameENST00000531049ENST00000355150C12orf36chr12

13529157

-KANK2chr19

11289396

-
In-frameENST00000531049ENST00000432929C12orf36chr12

13529157

-KANK2chr19

11289396

-
In-frameENST00000531049ENST00000586659C12orf36chr12

13529157

-KANK2chr19

11289396

-
In-frameENST00000539026ENST00000355150C12orf36chr12

13529157

-KANK2chr19

11289396

-
In-frameENST00000539026ENST00000432929C12orf36chr12

13529157

-KANK2chr19

11289396

-
In-frameENST00000539026ENST00000586659C12orf36chr12

13529157

-KANK2chr19

11289396

-
intron-3CDSENST00000532841ENST00000355150C12orf36chr12

13529157

-KANK2chr19

11289396

-
intron-3CDSENST00000532841ENST00000432929C12orf36chr12

13529157

-KANK2chr19

11289396

-
intron-3CDSENST00000532841ENST00000586659C12orf36chr12

13529157

-KANK2chr19

11289396

-
intron-intronENST00000532841ENST00000587317C12orf36chr12

13529157

-KANK2chr19

11289396

-
intron-intronENST00000532841ENST00000589359C12orf36chr12

13529157

-KANK2chr19

11289396

-
intron-intronENST00000532841ENST00000589894C12orf36chr12

13529157

-KANK2chr19

11289396

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000318426C12orf36chr1213529157-ENST00000586659KANK2chr1911289396-39984003451706453
ENST00000318426C12orf36chr1213529157-ENST00000355150KANK2chr1911289396-39974003451706453
ENST00000318426C12orf36chr1213529157-ENST00000432929KANK2chr1911289396-40214003451730461
ENST00000539026C12orf36chr1213529157-ENST00000586659KANK2chr1911289396-39623643091670453
ENST00000539026C12orf36chr1213529157-ENST00000355150KANK2chr1911289396-39613643091670453
ENST00000539026C12orf36chr1213529157-ENST00000432929KANK2chr1911289396-39853643091694461
ENST00000531049C12orf36chr1213529157-ENST00000586659KANK2chr1911289396-42816838801989369
ENST00000531049C12orf36chr1213529157-ENST00000355150KANK2chr1911289396-42806838801989369
ENST00000531049C12orf36chr1213529157-ENST00000432929KANK2chr1911289396-43046838592013384

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000318426ENST00000586659C12orf36chr1213529157-KANK2chr1911289396-0.0024297050.99757034
ENST00000318426ENST00000355150C12orf36chr1213529157-KANK2chr1911289396-0.0024257950.99757415
ENST00000318426ENST00000432929C12orf36chr1213529157-KANK2chr1911289396-0.00248730.9975127
ENST00000539026ENST00000586659C12orf36chr1213529157-KANK2chr1911289396-0.0024465160.9975535
ENST00000539026ENST00000355150C12orf36chr1213529157-KANK2chr1911289396-0.0024424570.9975575
ENST00000539026ENST00000432929C12orf36chr1213529157-KANK2chr1911289396-0.002502190.99749774
ENST00000531049ENST00000586659C12orf36chr1213529157-KANK2chr1911289396-0.0022880880.9977119
ENST00000531049ENST00000355150C12orf36chr1213529157-KANK2chr1911289396-0.002285650.9977144
ENST00000531049ENST00000432929C12orf36chr1213529157-KANK2chr1911289396-0.0023486430.9976514

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Fusion Genomic Features for C12orf36-KANK2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for C12orf36-KANK2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:13529157/chr19:11289396)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneKANK2chr12:13529157chr19:11289396ENST00000355150111425_428416852.0Compositional biasNote=Poly-Ser
TgeneKANK2chr12:13529157chr19:11289396ENST00000432929313425_428416860.0Compositional biasNote=Poly-Ser
TgeneKANK2chr12:13529157chr19:11289396ENST00000586659313425_428416852.0Compositional biasNote=Poly-Ser
TgeneKANK2chr12:13529157chr19:11289396ENST00000589359313425_428416860.0Compositional biasNote=Poly-Ser
TgeneKANK2chr12:13529157chr19:11289396ENST00000589894110425_428416842.0Compositional biasNote=Poly-Ser
TgeneKANK2chr12:13529157chr19:11289396ENST00000355150111666_696416852.0RepeatNote=ANK 1
TgeneKANK2chr12:13529157chr19:11289396ENST00000355150111700_733416852.0RepeatNote=ANK 2
TgeneKANK2chr12:13529157chr19:11289396ENST00000355150111738_767416852.0RepeatNote=ANK 3
TgeneKANK2chr12:13529157chr19:11289396ENST00000355150111771_801416852.0RepeatNote=ANK 4
TgeneKANK2chr12:13529157chr19:11289396ENST00000355150111805_835416852.0RepeatNote=ANK 5
TgeneKANK2chr12:13529157chr19:11289396ENST00000432929313666_696416860.0RepeatNote=ANK 1
TgeneKANK2chr12:13529157chr19:11289396ENST00000432929313700_733416860.0RepeatNote=ANK 2
TgeneKANK2chr12:13529157chr19:11289396ENST00000432929313738_767416860.0RepeatNote=ANK 3
TgeneKANK2chr12:13529157chr19:11289396ENST00000432929313771_801416860.0RepeatNote=ANK 4
TgeneKANK2chr12:13529157chr19:11289396ENST00000432929313805_835416860.0RepeatNote=ANK 5
TgeneKANK2chr12:13529157chr19:11289396ENST00000586659313666_696416852.0RepeatNote=ANK 1
TgeneKANK2chr12:13529157chr19:11289396ENST00000586659313700_733416852.0RepeatNote=ANK 2
TgeneKANK2chr12:13529157chr19:11289396ENST00000586659313738_767416852.0RepeatNote=ANK 3
TgeneKANK2chr12:13529157chr19:11289396ENST00000586659313771_801416852.0RepeatNote=ANK 4
TgeneKANK2chr12:13529157chr19:11289396ENST00000586659313805_835416852.0RepeatNote=ANK 5
TgeneKANK2chr12:13529157chr19:11289396ENST00000589359313666_696416860.0RepeatNote=ANK 1
TgeneKANK2chr12:13529157chr19:11289396ENST00000589359313700_733416860.0RepeatNote=ANK 2
TgeneKANK2chr12:13529157chr19:11289396ENST00000589359313738_767416860.0RepeatNote=ANK 3
TgeneKANK2chr12:13529157chr19:11289396ENST00000589359313771_801416860.0RepeatNote=ANK 4
TgeneKANK2chr12:13529157chr19:11289396ENST00000589359313805_835416860.0RepeatNote=ANK 5
TgeneKANK2chr12:13529157chr19:11289396ENST00000589894110666_696416842.0RepeatNote=ANK 1
TgeneKANK2chr12:13529157chr19:11289396ENST00000589894110700_733416842.0RepeatNote=ANK 2
TgeneKANK2chr12:13529157chr19:11289396ENST00000589894110738_767416842.0RepeatNote=ANK 3
TgeneKANK2chr12:13529157chr19:11289396ENST00000589894110771_801416842.0RepeatNote=ANK 4
TgeneKANK2chr12:13529157chr19:11289396ENST00000589894110805_835416842.0RepeatNote=ANK 5

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneKANK2chr12:13529157chr19:11289396ENST00000355150111183_234416852.0Coiled coilOntology_term=ECO:0000255
TgeneKANK2chr12:13529157chr19:11289396ENST00000355150111282_312416852.0Coiled coilOntology_term=ECO:0000255
TgeneKANK2chr12:13529157chr19:11289396ENST00000432929313183_234416860.0Coiled coilOntology_term=ECO:0000255
TgeneKANK2chr12:13529157chr19:11289396ENST00000432929313282_312416860.0Coiled coilOntology_term=ECO:0000255
TgeneKANK2chr12:13529157chr19:11289396ENST00000586659313183_234416852.0Coiled coilOntology_term=ECO:0000255
TgeneKANK2chr12:13529157chr19:11289396ENST00000586659313282_312416852.0Coiled coilOntology_term=ECO:0000255
TgeneKANK2chr12:13529157chr19:11289396ENST00000589359313183_234416860.0Coiled coilOntology_term=ECO:0000255
TgeneKANK2chr12:13529157chr19:11289396ENST00000589359313282_312416860.0Coiled coilOntology_term=ECO:0000255
TgeneKANK2chr12:13529157chr19:11289396ENST00000589894110183_234416842.0Coiled coilOntology_term=ECO:0000255
TgeneKANK2chr12:13529157chr19:11289396ENST00000589894110282_312416842.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for C12orf36-KANK2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>10822_10822_1_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000318426_KANK2_chr19_11289396_ENST00000355150_length(transcript)=3997nt_BP=400nt
GCAGACTTGAATAGAACTAAAAGGAAGAGGAAGGGCAAATTTGTTGGCTGCTTGAGCTGGGATATTCATCTTTCTCCTGATCTTGGACAT
CAGAACTCCTGATTCTCAAGCCTTTGGGTTTGGACTGGAGGCACCAGCTTTCCTGGGCCTCCAGCTTGCAGATGGCATATCATGGAACTT
CTCAGCCTCCAAATTCATAACTCTAATACACCAGTACAATGGAAAGATTCCTAAATTCAAAAGCCAGAAGGCTGGGTTCCTGTTCCCACC
CTGCCTTTTACCTTCTGTGTGTTCCTGATGAAGACACTTCATGCTCCACTATTTACTTACCTCTGAAACGAAGGGCTGACCCAGATCAGT
TGTTCTCTGACCTGCTTGGAGGGACTCAGAGGCTGTGGAGGCCTCCCAGAAGTTCCTGCCGAATCGTCTTCGTCACCCCCGGGGTCCGAG
GTAGCCTCCCTTACACAGCCTGAGAAGAGCACAGGCCGAGTGCCCACCCAGGAGCCCACCCACAGGGAGCCCACCAGGCAAGCAGCCTCC
CAAGAGTCCGAGGAGGCCGGGGGCACCGGCGGGCCCCCGGCAGGCGTGCGATCTATCATGAAACGGAAAGAGGAGGTTGCAGACCCCACG
GCCCACCGGAGGAGCCTCCAGTTCGTGGGGGTCAACGGCGGGTATGAGTCGTCATCCGAGGACTCCAGCACAGCAGAGAACATCTCAGAC
AACGACAGCACAGAGAACGAGGCCCCAGAGCCGAGGGAGAGGGTTCCGAGTGTGGCCGAAGCCCCCCAGCTCAGGCCTGCAGGGACGGCA
GCGGCCAAGACCAGCCGGCAGGAGTGTCAGCTGTCTCGAGAATCTCAGCACATACCCACTGCTGAGGGGGCATCAGGATCAAACACGGAG
GAGGAGATCAGGATGGAGCTAAGCCCTGACCTCATCTCAGCCTGCTTGGCCCTGGAAAAGTACCTGGACAATCCCAACGCCCTCACAGAG
CGGGAGCTGAAAGTGGCCTACACCACAGTGCTGCAGGAGTGGCTGCGCCTGGCCTGCCGCAGCGACGCACACCCCGAGCTGGTGCGGCGG
CACCTGGTCACGTTCCGGGCCATGTCTGCGCGGCTGCTGGACTACGTGGTCAACATCGCCGACAGCAACGGCAACACAGCCCTGCACTAC
TCCGTGTCTCATGCCAACTTCCCCGTGGTGCAGCAGCTGCTCGACAGCGGTGTCTGCAAGGTGGACAAACAGAACCGTGCTGGCTACAGC
CCTATTATGCTCACCGCCCTGGCCACCCTGAAGACCCAGGACGACATCGAGACTGTCCTTCAGCTCTTCCGGCTTGGCAACATCAATGCC
AAAGCCAGCCAGGCAGGACAGACGGCCCTGATGCTGGCCGTCAGCCACGGGCGGGTGGACGTTGTCAAAGCCCTGCTGGCCTGTGAGGCA
GATGTCAACGTGCAAGATGATGACGGCTCCACGGCCCTCATGTGCGCCTGTGAGCACGGCCACAAGGAGATCGCGGGGCTGCTGCTGGCC
GTGCCCAGCTGTGACATCTCACTCACAGATCGCGATGGGAGCACAGCTCTGATGGTGGCCTTGGACGCAGGGCAGAGTGAGATTGCGTCC
ATGCTGTATTCCCGCATGAACATCAAGTGCTCGTTTGCCCCAATGTCAGATGACGAGAGCCCTACATCATCCTCGGCAGAAGAGTAGCCG
TGAGGGAGGCGGGGACCAGCCAGACCGGGAGCAAACCGTCCCTTGTCCCCGTCTCCTCCCTGTTCCCGTTCCTCCCTGGCCCACCCCACT
CACACTCCCCAAGGCCCACGGCTCAAAGGCAAGCGAGCTCTCCCTCTGCTTCCCTGGGGGAGCCCCGACGGCCACAGGACTCCAGCTCCA
AGTGGGTTTTCTTGGCTCCCCTGTTCAAAGTGGCCACAGCGCAGACCGAAGCAAAATTCTTGTATACATTGGCGCCAGGGCTGATGCTGG
GGTGTGGGTTTTATGAAGAACATTGAGAACAATCAGCTGGTAATTATGGATGGAGGAAGAGGGAGAGGAAAAAAATATTGTATTTTTGAA
TCATTGTTGCAGGAGGGGGTGGGAATCTTAGGATTTGTTGCCAGATTTGAAAGTCACTGGAACTTGCATATTTTCATTTTAATCCTAAGT
GTTATTACGCACCAGTTGGGGTTCACCCTTCATCCCCCACATTTAATTGTCTGATATAGAATAGTGTTGTGTCCACTGCCCCGCTAGACG
GCTTTCTTAGGGGAATTTTCTTCTGGTTGTTTCACAAGACAGATTCTGTCCTTGTCACCCGGGACAGAAAACTCAGTCTTTTCACCCTCA
TTCAGATGAAGGGACTCAGGACAGGCTCTGTGACTTACAGGGACCCAATCAATTCACAATGAGAAATTACCGGCCAGGCGTGGTGACTCA
CGTCTGTAATCCCAGCACTTTGGGAGGGCAAGGCAAGAGCTTGAGCTTGAGCCTAGACGTTAAAGACCAGCCTGGGCAACACAGCAAGAC
CCATCTCTACAAGAAATTTAAAAACTAGCCAGGCGTGGTGGTGCGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGCCCTGGAGGTCGA
GGCTACAGTGAGCTATGATCACACCATTGCACTTCAGCCTGGGCGACACAGCGAGACCCTGTCTCAAGAAAGAAAAGAAAAAGAGACAAA
TTACCCAGAAACCCCTCCCTTCCCCACATGGAGGCCTTGGCAAATGTTAATTTTCCTAGAAAATCCTTCAGACCTGAAGACGCAGGAAAA
GAATCTGGCTCTCAGGGTGGCTTCTGCGTCCCCGCCGCCAGGCCCCAGACTATGGTCACAGGGCCGTCCTGTTCCTCCCCGGGACTCCAG
AATTTCTCTCCTCAAAGGAAAGAAAACAGGGCATGCGCTTGTTGGCAAAACGCAGGGCCGGCTCCCAAAAACCCCATGTGTGTACGATTA
AAAGTTGGCCGTCCCCAGGCCTCCCAGCGCAAACTTCAAGAGACAGGGCTTTGCTGAAAACCAAACATGGGCCAGCTGGGCTTTTTAACA
ACCTAGAGACTTTCCGGAGCTGCCTGGAACAGAGCCTGCGGGAAACGGGGCTTGCCAGAGACACTCACAGTTTCCTTCATGGCCTGTTTT
GGTCCCCTAAGAATCTCCACATCATTGTCTTTCTTGTGCCTTTTCCTTGGTGAGCAACAGAAAGGGAAGGGTTCCAAGCCTCTAAAAATG
TGCTTTGTGATCAGGAGTGCGCTCCAAACCAAATACGCGCGCTGCCCTTTCGAGGCCAGTGAGCTCAGCCTCCAAGGCTTTAAAGCCACA
TTTCAGCAAGAGAAAGCGCTGAGAGCTCGCAGGTTCATTAAAGAAGGCAAAGCACTGGTTTCTCTCCTTAGAAAAGTAGGTTTCTTGGCT
TGATGTAGACTGGCTTGCTTTGATTTTTAGTGAAGGGAATGTACGTAAAACAAAATAGGGCTTGGCTGGTCAAAGGAGACAAGCAGGATG
GATGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGAATAGATAGATGGTGTTTGCATGTAAATTGCAGAGAAAACAAAACC
AAAGCTGATTGGAAACAATTAATTGTGGGTGTCTGAGGGGGAAGGTCGCAGCTTTGGGCAGCTTTGAGAAGCGGTACAAGAGTTCTGTGC
CTGTGTGTCCAGCCCTGGAGCCAGCCAGTGCATTTATTTTAAGCTCTTAGAAGCAACTCCTTGGCCCAGGAATGCGTGACCCCTGAGATG
GGTCCACGCATCTCTCTACACTTCCTTCTCTCCGTGGGATACTGGACTCGTGCCTCTGCGCCCATTCTCTTCTCACGCATATCCATGAGC
TTTAATTTCACTTTCTGATCACGGTACGTCCATAAAGCCAGTATTACACTTAAATGAAGTATTCTTTTTTGTAATCGTTTTTTTTAGAAG
GTAAACAAATTTAATAAAGCTACCAATAATGTTGATG

>10822_10822_1_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000318426_KANK2_chr19_11289396_ENST00000355150_length(amino acids)=453AA_BP=18
MTQISCSLTCLEGLRGCGGLPEVPAESSSSPPGSEVASLTQPEKSTGRVPTQEPTHREPTRQAASQESEEAGGTGGPPAGVRSIMKRKEE
VADPTAHRRSLQFVGVNGGYESSSEDSSTAENISDNDSTENEAPEPRERVPSVAEAPQLRPAGTAAAKTSRQECQLSRESQHIPTAEGAS
GSNTEEEIRMELSPDLISACLALEKYLDNPNALTERELKVAYTTVLQEWLRLACRSDAHPELVRRHLVTFRAMSARLLDYVVNIADSNGN
TALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIETVLQLFRLGNINAKASQAGQTALMLAVSHGRVDVVKAL
LACEADVNVQDDDGSTALMCACEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNIKCSFAPMSDDESPTSSS
AEE

--------------------------------------------------------------
>10822_10822_2_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000318426_KANK2_chr19_11289396_ENST00000432929_length(transcript)=4021nt_BP=400nt
GCAGACTTGAATAGAACTAAAAGGAAGAGGAAGGGCAAATTTGTTGGCTGCTTGAGCTGGGATATTCATCTTTCTCCTGATCTTGGACAT
CAGAACTCCTGATTCTCAAGCCTTTGGGTTTGGACTGGAGGCACCAGCTTTCCTGGGCCTCCAGCTTGCAGATGGCATATCATGGAACTT
CTCAGCCTCCAAATTCATAACTCTAATACACCAGTACAATGGAAAGATTCCTAAATTCAAAAGCCAGAAGGCTGGGTTCCTGTTCCCACC
CTGCCTTTTACCTTCTGTGTGTTCCTGATGAAGACACTTCATGCTCCACTATTTACTTACCTCTGAAACGAAGGGCTGACCCAGATCAGT
TGTTCTCTGACCTGCTTGGAGGGACTCAGAGGCTGTGGAGGCCTCCCAGAAGTTCCTGCCGAATCGTCTTCGTCACCCCCGGGGTCCGAG
GTAGCCTCCCTTACACAGCCTGAGAAGAGCACAGGCCGAGTGCCCACCCAGGAGCCCACCCACAGGGAGCCCACCAGGCAAGCAGCCTCC
CAAGAGTCCGAGGAGGCCGGGGGCACCGCACCTCCGCTGTCCTCCCCTCCAGGCGGGCCCCCGGCAGGCGTGCGATCTATCATGAAACGG
AAAGAGGAGGTTGCAGACCCCACGGCCCACCGGAGGAGCCTCCAGTTCGTGGGGGTCAACGGCGGGTATGAGTCGTCATCCGAGGACTCC
AGCACAGCAGAGAACATCTCAGACAACGACAGCACAGAGAACGAGGCCCCAGAGCCGAGGGAGAGGGTTCCGAGTGTGGCCGAAGCCCCC
CAGCTCAGGCCTGCAGGGACGGCAGCGGCCAAGACCAGCCGGCAGGAGTGTCAGCTGTCTCGAGAATCTCAGCACATACCCACTGCTGAG
GGGGCATCAGGATCAAACACGGAGGAGGAGATCAGGATGGAGCTAAGCCCTGACCTCATCTCAGCCTGCTTGGCCCTGGAAAAGTACCTG
GACAATCCCAACGCCCTCACAGAGCGGGAGCTGAAAGTGGCCTACACCACAGTGCTGCAGGAGTGGCTGCGCCTGGCCTGCCGCAGCGAC
GCACACCCCGAGCTGGTGCGGCGGCACCTGGTCACGTTCCGGGCCATGTCTGCGCGGCTGCTGGACTACGTGGTCAACATCGCCGACAGC
AACGGCAACACAGCCCTGCACTACTCCGTGTCTCATGCCAACTTCCCCGTGGTGCAGCAGCTGCTCGACAGCGGTGTCTGCAAGGTGGAC
AAACAGAACCGTGCTGGCTACAGCCCTATTATGCTCACCGCCCTGGCCACCCTGAAGACCCAGGACGACATCGAGACTGTCCTTCAGCTC
TTCCGGCTTGGCAACATCAATGCCAAAGCCAGCCAGGCAGGACAGACGGCCCTGATGCTGGCCGTCAGCCACGGGCGGGTGGACGTTGTC
AAAGCCCTGCTGGCCTGTGAGGCAGATGTCAACGTGCAAGATGATGACGGCTCCACGGCCCTCATGTGCGCCTGTGAGCACGGCCACAAG
GAGATCGCGGGGCTGCTGCTGGCCGTGCCCAGCTGTGACATCTCACTCACAGATCGCGATGGGAGCACAGCTCTGATGGTGGCCTTGGAC
GCAGGGCAGAGTGAGATTGCGTCCATGCTGTATTCCCGCATGAACATCAAGTGCTCGTTTGCCCCAATGTCAGATGACGAGAGCCCTACA
TCATCCTCGGCAGAAGAGTAGCCGTGAGGGAGGCGGGGACCAGCCAGACCGGGAGCAAACCGTCCCTTGTCCCCGTCTCCTCCCTGTTCC
CGTTCCTCCCTGGCCCACCCCACTCACACTCCCCAAGGCCCACGGCTCAAAGGCAAGCGAGCTCTCCCTCTGCTTCCCTGGGGGAGCCCC
GACGGCCACAGGACTCCAGCTCCAAGTGGGTTTTCTTGGCTCCCCTGTTCAAAGTGGCCACAGCGCAGACCGAAGCAAAATTCTTGTATA
CATTGGCGCCAGGGCTGATGCTGGGGTGTGGGTTTTATGAAGAACATTGAGAACAATCAGCTGGTAATTATGGATGGAGGAAGAGGGAGA
GGAAAAAAATATTGTATTTTTGAATCATTGTTGCAGGAGGGGGTGGGAATCTTAGGATTTGTTGCCAGATTTGAAAGTCACTGGAACTTG
CATATTTTCATTTTAATCCTAAGTGTTATTACGCACCAGTTGGGGTTCACCCTTCATCCCCCACATTTAATTGTCTGATATAGAATAGTG
TTGTGTCCACTGCCCCGCTAGACGGCTTTCTTAGGGGAATTTTCTTCTGGTTGTTTCACAAGACAGATTCTGTCCTTGTCACCCGGGACA
GAAAACTCAGTCTTTTCACCCTCATTCAGATGAAGGGACTCAGGACAGGCTCTGTGACTTACAGGGACCCAATCAATTCACAATGAGAAA
TTACCGGCCAGGCGTGGTGACTCACGTCTGTAATCCCAGCACTTTGGGAGGGCAAGGCAAGAGCTTGAGCTTGAGCCTAGACGTTAAAGA
CCAGCCTGGGCAACACAGCAAGACCCATCTCTACAAGAAATTTAAAAACTAGCCAGGCGTGGTGGTGCGCGCCTGTAGTCCCAGCTACTT
GGGAGGCTGAGCCCTGGAGGTCGAGGCTACAGTGAGCTATGATCACACCATTGCACTTCAGCCTGGGCGACACAGCGAGACCCTGTCTCA
AGAAAGAAAAGAAAAAGAGACAAATTACCCAGAAACCCCTCCCTTCCCCACATGGAGGCCTTGGCAAATGTTAATTTTCCTAGAAAATCC
TTCAGACCTGAAGACGCAGGAAAAGAATCTGGCTCTCAGGGTGGCTTCTGCGTCCCCGCCGCCAGGCCCCAGACTATGGTCACAGGGCCG
TCCTGTTCCTCCCCGGGACTCCAGAATTTCTCTCCTCAAAGGAAAGAAAACAGGGCATGCGCTTGTTGGCAAAACGCAGGGCCGGCTCCC
AAAAACCCCATGTGTGTACGATTAAAAGTTGGCCGTCCCCAGGCCTCCCAGCGCAAACTTCAAGAGACAGGGCTTTGCTGAAAACCAAAC
ATGGGCCAGCTGGGCTTTTTAACAACCTAGAGACTTTCCGGAGCTGCCTGGAACAGAGCCTGCGGGAAACGGGGCTTGCCAGAGACACTC
ACAGTTTCCTTCATGGCCTGTTTTGGTCCCCTAAGAATCTCCACATCATTGTCTTTCTTGTGCCTTTTCCTTGGTGAGCAACAGAAAGGG
AAGGGTTCCAAGCCTCTAAAAATGTGCTTTGTGATCAGGAGTGCGCTCCAAACCAAATACGCGCGCTGCCCTTTCGAGGCCAGTGAGCTC
AGCCTCCAAGGCTTTAAAGCCACATTTCAGCAAGAGAAAGCGCTGAGAGCTCGCAGGTTCATTAAAGAAGGCAAAGCACTGGTTTCTCTC
CTTAGAAAAGTAGGTTTCTTGGCTTGATGTAGACTGGCTTGCTTTGATTTTTAGTGAAGGGAATGTACGTAAAACAAAATAGGGCTTGGC
TGGTCAAAGGAGACAAGCAGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGAATAGATAGATGGTGTTTGCAT
GTAAATTGCAGAGAAAACAAAACCAAAGCTGATTGGAAACAATTAATTGTGGGTGTCTGAGGGGGAAGGTCGCAGCTTTGGGCAGCTTTG
AGAAGCGGTACAAGAGTTCTGTGCCTGTGTGTCCAGCCCTGGAGCCAGCCAGTGCATTTATTTTAAGCTCTTAGAAGCAACTCCTTGGCC
CAGGAATGCGTGACCCCTGAGATGGGTCCACGCATCTCTCTACACTTCCTTCTCTCCGTGGGATACTGGACTCGTGCCTCTGCGCCCATT
CTCTTCTCACGCATATCCATGAGCTTTAATTTCACTTTCTGATCACGGTACGTCCATAAAGCCAGTATTACACTTAAATGAAGTATTCTT
TTTTGTAATCGTTTTTTTTAGAAGGTAAACAAATTTAATAAAGCTACCAATAATGTTGATG

>10822_10822_2_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000318426_KANK2_chr19_11289396_ENST00000432929_length(amino acids)=461AA_BP=18
MTQISCSLTCLEGLRGCGGLPEVPAESSSSPPGSEVASLTQPEKSTGRVPTQEPTHREPTRQAASQESEEAGGTAPPLSSPPGGPPAGVR
SIMKRKEEVADPTAHRRSLQFVGVNGGYESSSEDSSTAENISDNDSTENEAPEPRERVPSVAEAPQLRPAGTAAAKTSRQECQLSRESQH
IPTAEGASGSNTEEEIRMELSPDLISACLALEKYLDNPNALTERELKVAYTTVLQEWLRLACRSDAHPELVRRHLVTFRAMSARLLDYVV
NIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIETVLQLFRLGNINAKASQAGQTALMLAVSHG
RVDVVKALLACEADVNVQDDDGSTALMCACEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNIKCSFAPMSD
DESPTSSSAEE

--------------------------------------------------------------
>10822_10822_3_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000318426_KANK2_chr19_11289396_ENST00000586659_length(transcript)=3998nt_BP=400nt
GCAGACTTGAATAGAACTAAAAGGAAGAGGAAGGGCAAATTTGTTGGCTGCTTGAGCTGGGATATTCATCTTTCTCCTGATCTTGGACAT
CAGAACTCCTGATTCTCAAGCCTTTGGGTTTGGACTGGAGGCACCAGCTTTCCTGGGCCTCCAGCTTGCAGATGGCATATCATGGAACTT
CTCAGCCTCCAAATTCATAACTCTAATACACCAGTACAATGGAAAGATTCCTAAATTCAAAAGCCAGAAGGCTGGGTTCCTGTTCCCACC
CTGCCTTTTACCTTCTGTGTGTTCCTGATGAAGACACTTCATGCTCCACTATTTACTTACCTCTGAAACGAAGGGCTGACCCAGATCAGT
TGTTCTCTGACCTGCTTGGAGGGACTCAGAGGCTGTGGAGGCCTCCCAGAAGTTCCTGCCGAATCGTCTTCGTCACCCCCGGGGTCCGAG
GTAGCCTCCCTTACACAGCCTGAGAAGAGCACAGGCCGAGTGCCCACCCAGGAGCCCACCCACAGGGAGCCCACCAGGCAAGCAGCCTCC
CAAGAGTCCGAGGAGGCCGGGGGCACCGGCGGGCCCCCGGCAGGCGTGCGATCTATCATGAAACGGAAAGAGGAGGTTGCAGACCCCACG
GCCCACCGGAGGAGCCTCCAGTTCGTGGGGGTCAACGGCGGGTATGAGTCGTCATCCGAGGACTCCAGCACAGCAGAGAACATCTCAGAC
AACGACAGCACAGAGAACGAGGCCCCAGAGCCGAGGGAGAGGGTTCCGAGTGTGGCCGAAGCCCCCCAGCTCAGGCCTGCAGGGACGGCA
GCGGCCAAGACCAGCCGGCAGGAGTGTCAGCTGTCTCGAGAATCTCAGCACATACCCACTGCTGAGGGGGCATCAGGATCAAACACGGAG
GAGGAGATCAGGATGGAGCTAAGCCCTGACCTCATCTCAGCCTGCTTGGCCCTGGAAAAGTACCTGGACAATCCCAACGCCCTCACAGAG
CGGGAGCTGAAAGTGGCCTACACCACAGTGCTGCAGGAGTGGCTGCGCCTGGCCTGCCGCAGCGACGCACACCCCGAGCTGGTGCGGCGG
CACCTGGTCACGTTCCGGGCCATGTCTGCGCGGCTGCTGGACTACGTGGTCAACATCGCCGACAGCAACGGCAACACAGCCCTGCACTAC
TCCGTGTCTCATGCCAACTTCCCCGTGGTGCAGCAGCTGCTCGACAGCGGTGTCTGCAAGGTGGACAAACAGAACCGTGCTGGCTACAGC
CCTATTATGCTCACCGCCCTGGCCACCCTGAAGACCCAGGACGACATCGAGACTGTCCTTCAGCTCTTCCGGCTTGGCAACATCAATGCC
AAAGCCAGCCAGGCAGGACAGACGGCCCTGATGCTGGCCGTCAGCCACGGGCGGGTGGACGTTGTCAAAGCCCTGCTGGCCTGTGAGGCA
GATGTCAACGTGCAAGATGATGACGGCTCCACGGCCCTCATGTGCGCCTGTGAGCACGGCCACAAGGAGATCGCGGGGCTGCTGCTGGCC
GTGCCCAGCTGTGACATCTCACTCACAGATCGCGATGGGAGCACAGCTCTGATGGTGGCCTTGGACGCAGGGCAGAGTGAGATTGCGTCC
ATGCTGTATTCCCGCATGAACATCAAGTGCTCGTTTGCCCCAATGTCAGATGACGAGAGCCCTACATCATCCTCGGCAGAAGAGTAGCCG
TGAGGGAGGCGGGGACCAGCCAGACCGGGAGCAAACCGTCCCTTGTCCCCGTCTCCTCCCTGTTCCCGTTCCTCCCTGGCCCACCCCACT
CACACTCCCCAAGGCCCACGGCTCAAAGGCAAGCGAGCTCTCCCTCTGCTTCCCTGGGGGAGCCCCGACGGCCACAGGACTCCAGCTCCA
AGTGGGTTTTCTTGGCTCCCCTGTTCAAAGTGGCCACAGCGCAGACCGAAGCAAAATTCTTGTATACATTGGCGCCAGGGCTGATGCTGG
GGTGTGGGTTTTATGAAGAACATTGAGAACAATCAGCTGGTAATTATGGATGGAGGAAGAGGGAGAGGAAAAAAATATTGTATTTTTGAA
TCATTGTTGCAGGAGGGGGTGGGAATCTTAGGATTTGTTGCCAGATTTGAAAGTCACTGGAACTTGCATATTTTCATTTTAATCCTAAGT
GTTATTACGCACCAGTTGGGGTTCACCCTTCATCCCCCACATTTAATTGTCTGATATAGAATAGTGTTGTGTCCACTGCCCCGCTAGACG
GCTTTCTTAGGGGAATTTTCTTCTGGTTGTTTCACAAGACAGATTCTGTCCTTGTCACCCGGGACAGAAAACTCAGTCTTTTCACCCTCA
TTCAGATGAAGGGACTCAGGACAGGCTCTGTGACTTACAGGGACCCAATCAATTCACAATGAGAAATTACCGGCCAGGCGTGGTGACTCA
CGTCTGTAATCCCAGCACTTTGGGAGGGCAAGGCAAGAGCTTGAGCTTGAGCCTAGACGTTAAAGACCAGCCTGGGCAACACAGCAAGAC
CCATCTCTACAAGAAATTTAAAAACTAGCCAGGCGTGGTGGTGCGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGCCCTGGAGGTCGA
GGCTACAGTGAGCTATGATCACACCATTGCACTTCAGCCTGGGCGACACAGCGAGACCCTGTCTCAAGAAAGAAAAGAAAAAGAGACAAA
TTACCCAGAAACCCCTCCCTTCCCCACATGGAGGCCTTGGCAAATGTTAATTTTCCTAGAAAATCCTTCAGACCTGAAGACGCAGGAAAA
GAATCTGGCTCTCAGGGTGGCTTCTGCGTCCCCGCCGCCAGGCCCCAGACTATGGTCACAGGGCCGTCCTGTTCCTCCCCGGGACTCCAG
AATTTCTCTCCTCAAAGGAAAGAAAACAGGGCATGCGCTTGTTGGCAAAACGCAGGGCCGGCTCCCAAAAACCCCATGTGTGTACGATTA
AAAGTTGGCCGTCCCCAGGCCTCCCAGCGCAAACTTCAAGAGACAGGGCTTTGCTGAAAACCAAACATGGGCCAGCTGGGCTTTTTAACA
ACCTAGAGACTTTCCGGAGCTGCCTGGAACAGAGCCTGCGGGAAACGGGGCTTGCCAGAGACACTCACAGTTTCCTTCATGGCCTGTTTT
GGTCCCCTAAGAATCTCCACATCATTGTCTTTCTTGTGCCTTTTCCTTGGTGAGCAACAGAAAGGGAAGGGTTCCAAGCCTCTAAAAATG
TGCTTTGTGATCAGGAGTGCGCTCCAAACCAAATACGCGCGCTGCCCTTTCGAGGCCAGTGAGCTCAGCCTCCAAGGCTTTAAAGCCACA
TTTCAGCAAGAGAAAGCGCTGAGAGCTCGCAGGTTCATTAAAGAAGGCAAAGCACTGGTTTCTCTCCTTAGAAAAGTAGGTTTCTTGGCT
TGATGTAGACTGGCTTGCTTTGATTTTTAGTGAAGGGAATGTACGTAAAACAAAATAGGGCTTGGCTGGTCAAAGGAGACAAGCAGGATG
GATGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGAATAGATAGATGGTGTTTGCATGTAAATTGCAGAGAAAACAAAACC
AAAGCTGATTGGAAACAATTAATTGTGGGTGTCTGAGGGGGAAGGTCGCAGCTTTGGGCAGCTTTGAGAAGCGGTACAAGAGTTCTGTGC
CTGTGTGTCCAGCCCTGGAGCCAGCCAGTGCATTTATTTTAAGCTCTTAGAAGCAACTCCTTGGCCCAGGAATGCGTGACCCCTGAGATG
GGTCCACGCATCTCTCTACACTTCCTTCTCTCCGTGGGATACTGGACTCGTGCCTCTGCGCCCATTCTCTTCTCACGCATATCCATGAGC
TTTAATTTCACTTTCTGATCACGGTACGTCCATAAAGCCAGTATTACACTTAAATGAAGTATTCTTTTTTGTAATCGTTTTTTTTAGAAG
GTAAACAAATTTAATAAAGCTACCAATAATGTTGATGA

>10822_10822_3_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000318426_KANK2_chr19_11289396_ENST00000586659_length(amino acids)=453AA_BP=18
MTQISCSLTCLEGLRGCGGLPEVPAESSSSPPGSEVASLTQPEKSTGRVPTQEPTHREPTRQAASQESEEAGGTGGPPAGVRSIMKRKEE
VADPTAHRRSLQFVGVNGGYESSSEDSSTAENISDNDSTENEAPEPRERVPSVAEAPQLRPAGTAAAKTSRQECQLSRESQHIPTAEGAS
GSNTEEEIRMELSPDLISACLALEKYLDNPNALTERELKVAYTTVLQEWLRLACRSDAHPELVRRHLVTFRAMSARLLDYVVNIADSNGN
TALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIETVLQLFRLGNINAKASQAGQTALMLAVSHGRVDVVKAL
LACEADVNVQDDDGSTALMCACEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNIKCSFAPMSDDESPTSSS
AEE

--------------------------------------------------------------
>10822_10822_4_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000531049_KANK2_chr19_11289396_ENST00000355150_length(transcript)=4280nt_BP=683nt
AGAGAAACAGCTTAGGGAGAAAGAGGCAGAGGACAAAGGAACTCGCCAGTTGCTTCTGCAAAAAACGAAAAAACAGAAAAAAATCTAAAT
GAGTTCTCCTGCAGTTGACAGGCTTTGATGTGTGGACCATCAGCAGGATTGCAAAGTGTTAACAGATGGAGAGGAAGGACAGGAGTGGAC
AGAGCTTCCCTCCCAGATGGAGTGATTGATTGATATTTACCACACGGAGTGATAGAGCAGTAGATCACCATGGGATGACAGCCTAGAGCT
TTAGCAGCAGGTCGACTTTGGTACTTGAATAGAACTAAAAGGAAGAGGAAGGGCAAATTTGTTGGCTGCTTGAGCTGGGATATTCATCTT
TCTCCTGATCTTGGACATCAGAACTCCTGATTCTCAAGCCTTTGGGTTTGGACTGGAGGCACCAGCTTTCCTGGGCCTCCAGCTTGCAGA
TGGCATATCATGGAACTTCTCAGCCTCCAAATTCATAACTCTAATACACCAGTACAATGGAAAGATTCCTAAATTCAAAAGCCAGAAGGC
TGGGTTCCTGTTCCCACCCTGCCTTTTACCTTCTGTGTGTTCCTGATGAAGACACTTCATGCTCCACTATTTACTTACCTCTGAAACGAA
GGGCTGACCCAGATCAGTTGTTCTCTGACCTGCTTGGAGGGACTCAGAGGCTGGCCTCCCAGAAGTTCCTGCCGAATCGTCTTCGTCACC
CCCGGGGTCCGAGGTAGCCTCCCTTACACAGCCTGAGAAGAGCACAGGCCGAGTGCCCACCCAGGAGCCCACCCACAGGGAGCCCACCAG
GCAAGCAGCCTCCCAAGAGTCCGAGGAGGCCGGGGGCACCGGCGGGCCCCCGGCAGGCGTGCGATCTATCATGAAACGGAAAGAGGAGGT
TGCAGACCCCACGGCCCACCGGAGGAGCCTCCAGTTCGTGGGGGTCAACGGCGGGTATGAGTCGTCATCCGAGGACTCCAGCACAGCAGA
GAACATCTCAGACAACGACAGCACAGAGAACGAGGCCCCAGAGCCGAGGGAGAGGGTTCCGAGTGTGGCCGAAGCCCCCCAGCTCAGGCC
TGCAGGGACGGCAGCGGCCAAGACCAGCCGGCAGGAGTGTCAGCTGTCTCGAGAATCTCAGCACATACCCACTGCTGAGGGGGCATCAGG
ATCAAACACGGAGGAGGAGATCAGGATGGAGCTAAGCCCTGACCTCATCTCAGCCTGCTTGGCCCTGGAAAAGTACCTGGACAATCCCAA
CGCCCTCACAGAGCGGGAGCTGAAAGTGGCCTACACCACAGTGCTGCAGGAGTGGCTGCGCCTGGCCTGCCGCAGCGACGCACACCCCGA
GCTGGTGCGGCGGCACCTGGTCACGTTCCGGGCCATGTCTGCGCGGCTGCTGGACTACGTGGTCAACATCGCCGACAGCAACGGCAACAC
AGCCCTGCACTACTCCGTGTCTCATGCCAACTTCCCCGTGGTGCAGCAGCTGCTCGACAGCGGTGTCTGCAAGGTGGACAAACAGAACCG
TGCTGGCTACAGCCCTATTATGCTCACCGCCCTGGCCACCCTGAAGACCCAGGACGACATCGAGACTGTCCTTCAGCTCTTCCGGCTTGG
CAACATCAATGCCAAAGCCAGCCAGGCAGGACAGACGGCCCTGATGCTGGCCGTCAGCCACGGGCGGGTGGACGTTGTCAAAGCCCTGCT
GGCCTGTGAGGCAGATGTCAACGTGCAAGATGATGACGGCTCCACGGCCCTCATGTGCGCCTGTGAGCACGGCCACAAGGAGATCGCGGG
GCTGCTGCTGGCCGTGCCCAGCTGTGACATCTCACTCACAGATCGCGATGGGAGCACAGCTCTGATGGTGGCCTTGGACGCAGGGCAGAG
TGAGATTGCGTCCATGCTGTATTCCCGCATGAACATCAAGTGCTCGTTTGCCCCAATGTCAGATGACGAGAGCCCTACATCATCCTCGGC
AGAAGAGTAGCCGTGAGGGAGGCGGGGACCAGCCAGACCGGGAGCAAACCGTCCCTTGTCCCCGTCTCCTCCCTGTTCCCGTTCCTCCCT
GGCCCACCCCACTCACACTCCCCAAGGCCCACGGCTCAAAGGCAAGCGAGCTCTCCCTCTGCTTCCCTGGGGGAGCCCCGACGGCCACAG
GACTCCAGCTCCAAGTGGGTTTTCTTGGCTCCCCTGTTCAAAGTGGCCACAGCGCAGACCGAAGCAAAATTCTTGTATACATTGGCGCCA
GGGCTGATGCTGGGGTGTGGGTTTTATGAAGAACATTGAGAACAATCAGCTGGTAATTATGGATGGAGGAAGAGGGAGAGGAAAAAAATA
TTGTATTTTTGAATCATTGTTGCAGGAGGGGGTGGGAATCTTAGGATTTGTTGCCAGATTTGAAAGTCACTGGAACTTGCATATTTTCAT
TTTAATCCTAAGTGTTATTACGCACCAGTTGGGGTTCACCCTTCATCCCCCACATTTAATTGTCTGATATAGAATAGTGTTGTGTCCACT
GCCCCGCTAGACGGCTTTCTTAGGGGAATTTTCTTCTGGTTGTTTCACAAGACAGATTCTGTCCTTGTCACCCGGGACAGAAAACTCAGT
CTTTTCACCCTCATTCAGATGAAGGGACTCAGGACAGGCTCTGTGACTTACAGGGACCCAATCAATTCACAATGAGAAATTACCGGCCAG
GCGTGGTGACTCACGTCTGTAATCCCAGCACTTTGGGAGGGCAAGGCAAGAGCTTGAGCTTGAGCCTAGACGTTAAAGACCAGCCTGGGC
AACACAGCAAGACCCATCTCTACAAGAAATTTAAAAACTAGCCAGGCGTGGTGGTGCGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAG
CCCTGGAGGTCGAGGCTACAGTGAGCTATGATCACACCATTGCACTTCAGCCTGGGCGACACAGCGAGACCCTGTCTCAAGAAAGAAAAG
AAAAAGAGACAAATTACCCAGAAACCCCTCCCTTCCCCACATGGAGGCCTTGGCAAATGTTAATTTTCCTAGAAAATCCTTCAGACCTGA
AGACGCAGGAAAAGAATCTGGCTCTCAGGGTGGCTTCTGCGTCCCCGCCGCCAGGCCCCAGACTATGGTCACAGGGCCGTCCTGTTCCTC
CCCGGGACTCCAGAATTTCTCTCCTCAAAGGAAAGAAAACAGGGCATGCGCTTGTTGGCAAAACGCAGGGCCGGCTCCCAAAAACCCCAT
GTGTGTACGATTAAAAGTTGGCCGTCCCCAGGCCTCCCAGCGCAAACTTCAAGAGACAGGGCTTTGCTGAAAACCAAACATGGGCCAGCT
GGGCTTTTTAACAACCTAGAGACTTTCCGGAGCTGCCTGGAACAGAGCCTGCGGGAAACGGGGCTTGCCAGAGACACTCACAGTTTCCTT
CATGGCCTGTTTTGGTCCCCTAAGAATCTCCACATCATTGTCTTTCTTGTGCCTTTTCCTTGGTGAGCAACAGAAAGGGAAGGGTTCCAA
GCCTCTAAAAATGTGCTTTGTGATCAGGAGTGCGCTCCAAACCAAATACGCGCGCTGCCCTTTCGAGGCCAGTGAGCTCAGCCTCCAAGG
CTTTAAAGCCACATTTCAGCAAGAGAAAGCGCTGAGAGCTCGCAGGTTCATTAAAGAAGGCAAAGCACTGGTTTCTCTCCTTAGAAAAGT
AGGTTTCTTGGCTTGATGTAGACTGGCTTGCTTTGATTTTTAGTGAAGGGAATGTACGTAAAACAAAATAGGGCTTGGCTGGTCAAAGGA
GACAAGCAGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGAATAGATAGATGGTGTTTGCATGTAAATTGCAG
AGAAAACAAAACCAAAGCTGATTGGAAACAATTAATTGTGGGTGTCTGAGGGGGAAGGTCGCAGCTTTGGGCAGCTTTGAGAAGCGGTAC
AAGAGTTCTGTGCCTGTGTGTCCAGCCCTGGAGCCAGCCAGTGCATTTATTTTAAGCTCTTAGAAGCAACTCCTTGGCCCAGGAATGCGT
GACCCCTGAGATGGGTCCACGCATCTCTCTACACTTCCTTCTCTCCGTGGGATACTGGACTCGTGCCTCTGCGCCCATTCTCTTCTCACG
CATATCCATGAGCTTTAATTTCACTTTCTGATCACGGTACGTCCATAAAGCCAGTATTACACTTAAATGAAGTATTCTTTTTTGTAATCG
TTTTTTTTAGAAGGTAAACAAATTTAATAAAGCTACCAATAATGTTGATG

>10822_10822_4_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000531049_KANK2_chr19_11289396_ENST00000355150_length(amino acids)=369AA_BP=
MKRKEEVADPTAHRRSLQFVGVNGGYESSSEDSSTAENISDNDSTENEAPEPRERVPSVAEAPQLRPAGTAAAKTSRQECQLSRESQHIP
TAEGASGSNTEEEIRMELSPDLISACLALEKYLDNPNALTERELKVAYTTVLQEWLRLACRSDAHPELVRRHLVTFRAMSARLLDYVVNI
ADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIETVLQLFRLGNINAKASQAGQTALMLAVSHGRV
DVVKALLACEADVNVQDDDGSTALMCACEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNIKCSFAPMSDDE
SPTSSSAEE

--------------------------------------------------------------
>10822_10822_5_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000531049_KANK2_chr19_11289396_ENST00000432929_length(transcript)=4304nt_BP=683nt
AGAGAAACAGCTTAGGGAGAAAGAGGCAGAGGACAAAGGAACTCGCCAGTTGCTTCTGCAAAAAACGAAAAAACAGAAAAAAATCTAAAT
GAGTTCTCCTGCAGTTGACAGGCTTTGATGTGTGGACCATCAGCAGGATTGCAAAGTGTTAACAGATGGAGAGGAAGGACAGGAGTGGAC
AGAGCTTCCCTCCCAGATGGAGTGATTGATTGATATTTACCACACGGAGTGATAGAGCAGTAGATCACCATGGGATGACAGCCTAGAGCT
TTAGCAGCAGGTCGACTTTGGTACTTGAATAGAACTAAAAGGAAGAGGAAGGGCAAATTTGTTGGCTGCTTGAGCTGGGATATTCATCTT
TCTCCTGATCTTGGACATCAGAACTCCTGATTCTCAAGCCTTTGGGTTTGGACTGGAGGCACCAGCTTTCCTGGGCCTCCAGCTTGCAGA
TGGCATATCATGGAACTTCTCAGCCTCCAAATTCATAACTCTAATACACCAGTACAATGGAAAGATTCCTAAATTCAAAAGCCAGAAGGC
TGGGTTCCTGTTCCCACCCTGCCTTTTACCTTCTGTGTGTTCCTGATGAAGACACTTCATGCTCCACTATTTACTTACCTCTGAAACGAA
GGGCTGACCCAGATCAGTTGTTCTCTGACCTGCTTGGAGGGACTCAGAGGCTGGCCTCCCAGAAGTTCCTGCCGAATCGTCTTCGTCACC
CCCGGGGTCCGAGGTAGCCTCCCTTACACAGCCTGAGAAGAGCACAGGCCGAGTGCCCACCCAGGAGCCCACCCACAGGGAGCCCACCAG
GCAAGCAGCCTCCCAAGAGTCCGAGGAGGCCGGGGGCACCGCACCTCCGCTGTCCTCCCCTCCAGGCGGGCCCCCGGCAGGCGTGCGATC
TATCATGAAACGGAAAGAGGAGGTTGCAGACCCCACGGCCCACCGGAGGAGCCTCCAGTTCGTGGGGGTCAACGGCGGGTATGAGTCGTC
ATCCGAGGACTCCAGCACAGCAGAGAACATCTCAGACAACGACAGCACAGAGAACGAGGCCCCAGAGCCGAGGGAGAGGGTTCCGAGTGT
GGCCGAAGCCCCCCAGCTCAGGCCTGCAGGGACGGCAGCGGCCAAGACCAGCCGGCAGGAGTGTCAGCTGTCTCGAGAATCTCAGCACAT
ACCCACTGCTGAGGGGGCATCAGGATCAAACACGGAGGAGGAGATCAGGATGGAGCTAAGCCCTGACCTCATCTCAGCCTGCTTGGCCCT
GGAAAAGTACCTGGACAATCCCAACGCCCTCACAGAGCGGGAGCTGAAAGTGGCCTACACCACAGTGCTGCAGGAGTGGCTGCGCCTGGC
CTGCCGCAGCGACGCACACCCCGAGCTGGTGCGGCGGCACCTGGTCACGTTCCGGGCCATGTCTGCGCGGCTGCTGGACTACGTGGTCAA
CATCGCCGACAGCAACGGCAACACAGCCCTGCACTACTCCGTGTCTCATGCCAACTTCCCCGTGGTGCAGCAGCTGCTCGACAGCGGTGT
CTGCAAGGTGGACAAACAGAACCGTGCTGGCTACAGCCCTATTATGCTCACCGCCCTGGCCACCCTGAAGACCCAGGACGACATCGAGAC
TGTCCTTCAGCTCTTCCGGCTTGGCAACATCAATGCCAAAGCCAGCCAGGCAGGACAGACGGCCCTGATGCTGGCCGTCAGCCACGGGCG
GGTGGACGTTGTCAAAGCCCTGCTGGCCTGTGAGGCAGATGTCAACGTGCAAGATGATGACGGCTCCACGGCCCTCATGTGCGCCTGTGA
GCACGGCCACAAGGAGATCGCGGGGCTGCTGCTGGCCGTGCCCAGCTGTGACATCTCACTCACAGATCGCGATGGGAGCACAGCTCTGAT
GGTGGCCTTGGACGCAGGGCAGAGTGAGATTGCGTCCATGCTGTATTCCCGCATGAACATCAAGTGCTCGTTTGCCCCAATGTCAGATGA
CGAGAGCCCTACATCATCCTCGGCAGAAGAGTAGCCGTGAGGGAGGCGGGGACCAGCCAGACCGGGAGCAAACCGTCCCTTGTCCCCGTC
TCCTCCCTGTTCCCGTTCCTCCCTGGCCCACCCCACTCACACTCCCCAAGGCCCACGGCTCAAAGGCAAGCGAGCTCTCCCTCTGCTTCC
CTGGGGGAGCCCCGACGGCCACAGGACTCCAGCTCCAAGTGGGTTTTCTTGGCTCCCCTGTTCAAAGTGGCCACAGCGCAGACCGAAGCA
AAATTCTTGTATACATTGGCGCCAGGGCTGATGCTGGGGTGTGGGTTTTATGAAGAACATTGAGAACAATCAGCTGGTAATTATGGATGG
AGGAAGAGGGAGAGGAAAAAAATATTGTATTTTTGAATCATTGTTGCAGGAGGGGGTGGGAATCTTAGGATTTGTTGCCAGATTTGAAAG
TCACTGGAACTTGCATATTTTCATTTTAATCCTAAGTGTTATTACGCACCAGTTGGGGTTCACCCTTCATCCCCCACATTTAATTGTCTG
ATATAGAATAGTGTTGTGTCCACTGCCCCGCTAGACGGCTTTCTTAGGGGAATTTTCTTCTGGTTGTTTCACAAGACAGATTCTGTCCTT
GTCACCCGGGACAGAAAACTCAGTCTTTTCACCCTCATTCAGATGAAGGGACTCAGGACAGGCTCTGTGACTTACAGGGACCCAATCAAT
TCACAATGAGAAATTACCGGCCAGGCGTGGTGACTCACGTCTGTAATCCCAGCACTTTGGGAGGGCAAGGCAAGAGCTTGAGCTTGAGCC
TAGACGTTAAAGACCAGCCTGGGCAACACAGCAAGACCCATCTCTACAAGAAATTTAAAAACTAGCCAGGCGTGGTGGTGCGCGCCTGTA
GTCCCAGCTACTTGGGAGGCTGAGCCCTGGAGGTCGAGGCTACAGTGAGCTATGATCACACCATTGCACTTCAGCCTGGGCGACACAGCG
AGACCCTGTCTCAAGAAAGAAAAGAAAAAGAGACAAATTACCCAGAAACCCCTCCCTTCCCCACATGGAGGCCTTGGCAAATGTTAATTT
TCCTAGAAAATCCTTCAGACCTGAAGACGCAGGAAAAGAATCTGGCTCTCAGGGTGGCTTCTGCGTCCCCGCCGCCAGGCCCCAGACTAT
GGTCACAGGGCCGTCCTGTTCCTCCCCGGGACTCCAGAATTTCTCTCCTCAAAGGAAAGAAAACAGGGCATGCGCTTGTTGGCAAAACGC
AGGGCCGGCTCCCAAAAACCCCATGTGTGTACGATTAAAAGTTGGCCGTCCCCAGGCCTCCCAGCGCAAACTTCAAGAGACAGGGCTTTG
CTGAAAACCAAACATGGGCCAGCTGGGCTTTTTAACAACCTAGAGACTTTCCGGAGCTGCCTGGAACAGAGCCTGCGGGAAACGGGGCTT
GCCAGAGACACTCACAGTTTCCTTCATGGCCTGTTTTGGTCCCCTAAGAATCTCCACATCATTGTCTTTCTTGTGCCTTTTCCTTGGTGA
GCAACAGAAAGGGAAGGGTTCCAAGCCTCTAAAAATGTGCTTTGTGATCAGGAGTGCGCTCCAAACCAAATACGCGCGCTGCCCTTTCGA
GGCCAGTGAGCTCAGCCTCCAAGGCTTTAAAGCCACATTTCAGCAAGAGAAAGCGCTGAGAGCTCGCAGGTTCATTAAAGAAGGCAAAGC
ACTGGTTTCTCTCCTTAGAAAAGTAGGTTTCTTGGCTTGATGTAGACTGGCTTGCTTTGATTTTTAGTGAAGGGAATGTACGTAAAACAA
AATAGGGCTTGGCTGGTCAAAGGAGACAAGCAGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGAATAGATAG
ATGGTGTTTGCATGTAAATTGCAGAGAAAACAAAACCAAAGCTGATTGGAAACAATTAATTGTGGGTGTCTGAGGGGGAAGGTCGCAGCT
TTGGGCAGCTTTGAGAAGCGGTACAAGAGTTCTGTGCCTGTGTGTCCAGCCCTGGAGCCAGCCAGTGCATTTATTTTAAGCTCTTAGAAG
CAACTCCTTGGCCCAGGAATGCGTGACCCCTGAGATGGGTCCACGCATCTCTCTACACTTCCTTCTCTCCGTGGGATACTGGACTCGTGC
CTCTGCGCCCATTCTCTTCTCACGCATATCCATGAGCTTTAATTTCACTTTCTGATCACGGTACGTCCATAAAGCCAGTATTACACTTAA
ATGAAGTATTCTTTTTTGTAATCGTTTTTTTTAGAAGGTAAACAAATTTAATAAAGCTACCAATAATGTTGATG

>10822_10822_5_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000531049_KANK2_chr19_11289396_ENST00000432929_length(amino acids)=384AA_BP=
MSSPPGGPPAGVRSIMKRKEEVADPTAHRRSLQFVGVNGGYESSSEDSSTAENISDNDSTENEAPEPRERVPSVAEAPQLRPAGTAAAKT
SRQECQLSRESQHIPTAEGASGSNTEEEIRMELSPDLISACLALEKYLDNPNALTERELKVAYTTVLQEWLRLACRSDAHPELVRRHLVT
FRAMSARLLDYVVNIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIETVLQLFRLGNINAKASQ
AGQTALMLAVSHGRVDVVKALLACEADVNVQDDDGSTALMCACEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYS
RMNIKCSFAPMSDDESPTSSSAEE

--------------------------------------------------------------
>10822_10822_6_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000531049_KANK2_chr19_11289396_ENST00000586659_length(transcript)=4281nt_BP=683nt
AGAGAAACAGCTTAGGGAGAAAGAGGCAGAGGACAAAGGAACTCGCCAGTTGCTTCTGCAAAAAACGAAAAAACAGAAAAAAATCTAAAT
GAGTTCTCCTGCAGTTGACAGGCTTTGATGTGTGGACCATCAGCAGGATTGCAAAGTGTTAACAGATGGAGAGGAAGGACAGGAGTGGAC
AGAGCTTCCCTCCCAGATGGAGTGATTGATTGATATTTACCACACGGAGTGATAGAGCAGTAGATCACCATGGGATGACAGCCTAGAGCT
TTAGCAGCAGGTCGACTTTGGTACTTGAATAGAACTAAAAGGAAGAGGAAGGGCAAATTTGTTGGCTGCTTGAGCTGGGATATTCATCTT
TCTCCTGATCTTGGACATCAGAACTCCTGATTCTCAAGCCTTTGGGTTTGGACTGGAGGCACCAGCTTTCCTGGGCCTCCAGCTTGCAGA
TGGCATATCATGGAACTTCTCAGCCTCCAAATTCATAACTCTAATACACCAGTACAATGGAAAGATTCCTAAATTCAAAAGCCAGAAGGC
TGGGTTCCTGTTCCCACCCTGCCTTTTACCTTCTGTGTGTTCCTGATGAAGACACTTCATGCTCCACTATTTACTTACCTCTGAAACGAA
GGGCTGACCCAGATCAGTTGTTCTCTGACCTGCTTGGAGGGACTCAGAGGCTGGCCTCCCAGAAGTTCCTGCCGAATCGTCTTCGTCACC
CCCGGGGTCCGAGGTAGCCTCCCTTACACAGCCTGAGAAGAGCACAGGCCGAGTGCCCACCCAGGAGCCCACCCACAGGGAGCCCACCAG
GCAAGCAGCCTCCCAAGAGTCCGAGGAGGCCGGGGGCACCGGCGGGCCCCCGGCAGGCGTGCGATCTATCATGAAACGGAAAGAGGAGGT
TGCAGACCCCACGGCCCACCGGAGGAGCCTCCAGTTCGTGGGGGTCAACGGCGGGTATGAGTCGTCATCCGAGGACTCCAGCACAGCAGA
GAACATCTCAGACAACGACAGCACAGAGAACGAGGCCCCAGAGCCGAGGGAGAGGGTTCCGAGTGTGGCCGAAGCCCCCCAGCTCAGGCC
TGCAGGGACGGCAGCGGCCAAGACCAGCCGGCAGGAGTGTCAGCTGTCTCGAGAATCTCAGCACATACCCACTGCTGAGGGGGCATCAGG
ATCAAACACGGAGGAGGAGATCAGGATGGAGCTAAGCCCTGACCTCATCTCAGCCTGCTTGGCCCTGGAAAAGTACCTGGACAATCCCAA
CGCCCTCACAGAGCGGGAGCTGAAAGTGGCCTACACCACAGTGCTGCAGGAGTGGCTGCGCCTGGCCTGCCGCAGCGACGCACACCCCGA
GCTGGTGCGGCGGCACCTGGTCACGTTCCGGGCCATGTCTGCGCGGCTGCTGGACTACGTGGTCAACATCGCCGACAGCAACGGCAACAC
AGCCCTGCACTACTCCGTGTCTCATGCCAACTTCCCCGTGGTGCAGCAGCTGCTCGACAGCGGTGTCTGCAAGGTGGACAAACAGAACCG
TGCTGGCTACAGCCCTATTATGCTCACCGCCCTGGCCACCCTGAAGACCCAGGACGACATCGAGACTGTCCTTCAGCTCTTCCGGCTTGG
CAACATCAATGCCAAAGCCAGCCAGGCAGGACAGACGGCCCTGATGCTGGCCGTCAGCCACGGGCGGGTGGACGTTGTCAAAGCCCTGCT
GGCCTGTGAGGCAGATGTCAACGTGCAAGATGATGACGGCTCCACGGCCCTCATGTGCGCCTGTGAGCACGGCCACAAGGAGATCGCGGG
GCTGCTGCTGGCCGTGCCCAGCTGTGACATCTCACTCACAGATCGCGATGGGAGCACAGCTCTGATGGTGGCCTTGGACGCAGGGCAGAG
TGAGATTGCGTCCATGCTGTATTCCCGCATGAACATCAAGTGCTCGTTTGCCCCAATGTCAGATGACGAGAGCCCTACATCATCCTCGGC
AGAAGAGTAGCCGTGAGGGAGGCGGGGACCAGCCAGACCGGGAGCAAACCGTCCCTTGTCCCCGTCTCCTCCCTGTTCCCGTTCCTCCCT
GGCCCACCCCACTCACACTCCCCAAGGCCCACGGCTCAAAGGCAAGCGAGCTCTCCCTCTGCTTCCCTGGGGGAGCCCCGACGGCCACAG
GACTCCAGCTCCAAGTGGGTTTTCTTGGCTCCCCTGTTCAAAGTGGCCACAGCGCAGACCGAAGCAAAATTCTTGTATACATTGGCGCCA
GGGCTGATGCTGGGGTGTGGGTTTTATGAAGAACATTGAGAACAATCAGCTGGTAATTATGGATGGAGGAAGAGGGAGAGGAAAAAAATA
TTGTATTTTTGAATCATTGTTGCAGGAGGGGGTGGGAATCTTAGGATTTGTTGCCAGATTTGAAAGTCACTGGAACTTGCATATTTTCAT
TTTAATCCTAAGTGTTATTACGCACCAGTTGGGGTTCACCCTTCATCCCCCACATTTAATTGTCTGATATAGAATAGTGTTGTGTCCACT
GCCCCGCTAGACGGCTTTCTTAGGGGAATTTTCTTCTGGTTGTTTCACAAGACAGATTCTGTCCTTGTCACCCGGGACAGAAAACTCAGT
CTTTTCACCCTCATTCAGATGAAGGGACTCAGGACAGGCTCTGTGACTTACAGGGACCCAATCAATTCACAATGAGAAATTACCGGCCAG
GCGTGGTGACTCACGTCTGTAATCCCAGCACTTTGGGAGGGCAAGGCAAGAGCTTGAGCTTGAGCCTAGACGTTAAAGACCAGCCTGGGC
AACACAGCAAGACCCATCTCTACAAGAAATTTAAAAACTAGCCAGGCGTGGTGGTGCGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAG
CCCTGGAGGTCGAGGCTACAGTGAGCTATGATCACACCATTGCACTTCAGCCTGGGCGACACAGCGAGACCCTGTCTCAAGAAAGAAAAG
AAAAAGAGACAAATTACCCAGAAACCCCTCCCTTCCCCACATGGAGGCCTTGGCAAATGTTAATTTTCCTAGAAAATCCTTCAGACCTGA
AGACGCAGGAAAAGAATCTGGCTCTCAGGGTGGCTTCTGCGTCCCCGCCGCCAGGCCCCAGACTATGGTCACAGGGCCGTCCTGTTCCTC
CCCGGGACTCCAGAATTTCTCTCCTCAAAGGAAAGAAAACAGGGCATGCGCTTGTTGGCAAAACGCAGGGCCGGCTCCCAAAAACCCCAT
GTGTGTACGATTAAAAGTTGGCCGTCCCCAGGCCTCCCAGCGCAAACTTCAAGAGACAGGGCTTTGCTGAAAACCAAACATGGGCCAGCT
GGGCTTTTTAACAACCTAGAGACTTTCCGGAGCTGCCTGGAACAGAGCCTGCGGGAAACGGGGCTTGCCAGAGACACTCACAGTTTCCTT
CATGGCCTGTTTTGGTCCCCTAAGAATCTCCACATCATTGTCTTTCTTGTGCCTTTTCCTTGGTGAGCAACAGAAAGGGAAGGGTTCCAA
GCCTCTAAAAATGTGCTTTGTGATCAGGAGTGCGCTCCAAACCAAATACGCGCGCTGCCCTTTCGAGGCCAGTGAGCTCAGCCTCCAAGG
CTTTAAAGCCACATTTCAGCAAGAGAAAGCGCTGAGAGCTCGCAGGTTCATTAAAGAAGGCAAAGCACTGGTTTCTCTCCTTAGAAAAGT
AGGTTTCTTGGCTTGATGTAGACTGGCTTGCTTTGATTTTTAGTGAAGGGAATGTACGTAAAACAAAATAGGGCTTGGCTGGTCAAAGGA
GACAAGCAGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGAATAGATAGATGGTGTTTGCATGTAAATTGCAG
AGAAAACAAAACCAAAGCTGATTGGAAACAATTAATTGTGGGTGTCTGAGGGGGAAGGTCGCAGCTTTGGGCAGCTTTGAGAAGCGGTAC
AAGAGTTCTGTGCCTGTGTGTCCAGCCCTGGAGCCAGCCAGTGCATTTATTTTAAGCTCTTAGAAGCAACTCCTTGGCCCAGGAATGCGT
GACCCCTGAGATGGGTCCACGCATCTCTCTACACTTCCTTCTCTCCGTGGGATACTGGACTCGTGCCTCTGCGCCCATTCTCTTCTCACG
CATATCCATGAGCTTTAATTTCACTTTCTGATCACGGTACGTCCATAAAGCCAGTATTACACTTAAATGAAGTATTCTTTTTTGTAATCG
TTTTTTTTAGAAGGTAAACAAATTTAATAAAGCTACCAATAATGTTGATGA

>10822_10822_6_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000531049_KANK2_chr19_11289396_ENST00000586659_length(amino acids)=369AA_BP=
MKRKEEVADPTAHRRSLQFVGVNGGYESSSEDSSTAENISDNDSTENEAPEPRERVPSVAEAPQLRPAGTAAAKTSRQECQLSRESQHIP
TAEGASGSNTEEEIRMELSPDLISACLALEKYLDNPNALTERELKVAYTTVLQEWLRLACRSDAHPELVRRHLVTFRAMSARLLDYVVNI
ADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIETVLQLFRLGNINAKASQAGQTALMLAVSHGRV
DVVKALLACEADVNVQDDDGSTALMCACEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNIKCSFAPMSDDE
SPTSSSAEE

--------------------------------------------------------------
>10822_10822_7_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000539026_KANK2_chr19_11289396_ENST00000355150_length(transcript)=3961nt_BP=364nt
AAATTTGTTGGCTGCTTGAGCTGGGATATTCATCTTTCTCCTGATCTTGGACATCAGAACTCCTGATTCTCAAGCCTTTGGGTTTGGACT
GGAGGCACCAGCTTTCCTGGGCCTCCAGCTTGCAGATGGCATATCATGGAACTTCTCAGCCTCCAAATTCATAACTCTAATACACCAGTA
CAATGGAAAGATTCCTAAATTCAAAAGCCAGAAGGCTGGGTTCCTGTTCCCACCCTGCCTTTTACCTTCTGTGTGTTCCTGATGAAGACA
CTTCATGCTCCACTATTTACTTACCTCTGAAACGAAGGGCTGACCCAGATCAGTTGTTCTCTGACCTGCTTGGAGGGACTCAGAGGCTGT
GGAGGCCTCCCAGAAGTTCCTGCCGAATCGTCTTCGTCACCCCCGGGGTCCGAGGTAGCCTCCCTTACACAGCCTGAGAAGAGCACAGGC
CGAGTGCCCACCCAGGAGCCCACCCACAGGGAGCCCACCAGGCAAGCAGCCTCCCAAGAGTCCGAGGAGGCCGGGGGCACCGGCGGGCCC
CCGGCAGGCGTGCGATCTATCATGAAACGGAAAGAGGAGGTTGCAGACCCCACGGCCCACCGGAGGAGCCTCCAGTTCGTGGGGGTCAAC
GGCGGGTATGAGTCGTCATCCGAGGACTCCAGCACAGCAGAGAACATCTCAGACAACGACAGCACAGAGAACGAGGCCCCAGAGCCGAGG
GAGAGGGTTCCGAGTGTGGCCGAAGCCCCCCAGCTCAGGCCTGCAGGGACGGCAGCGGCCAAGACCAGCCGGCAGGAGTGTCAGCTGTCT
CGAGAATCTCAGCACATACCCACTGCTGAGGGGGCATCAGGATCAAACACGGAGGAGGAGATCAGGATGGAGCTAAGCCCTGACCTCATC
TCAGCCTGCTTGGCCCTGGAAAAGTACCTGGACAATCCCAACGCCCTCACAGAGCGGGAGCTGAAAGTGGCCTACACCACAGTGCTGCAG
GAGTGGCTGCGCCTGGCCTGCCGCAGCGACGCACACCCCGAGCTGGTGCGGCGGCACCTGGTCACGTTCCGGGCCATGTCTGCGCGGCTG
CTGGACTACGTGGTCAACATCGCCGACAGCAACGGCAACACAGCCCTGCACTACTCCGTGTCTCATGCCAACTTCCCCGTGGTGCAGCAG
CTGCTCGACAGCGGTGTCTGCAAGGTGGACAAACAGAACCGTGCTGGCTACAGCCCTATTATGCTCACCGCCCTGGCCACCCTGAAGACC
CAGGACGACATCGAGACTGTCCTTCAGCTCTTCCGGCTTGGCAACATCAATGCCAAAGCCAGCCAGGCAGGACAGACGGCCCTGATGCTG
GCCGTCAGCCACGGGCGGGTGGACGTTGTCAAAGCCCTGCTGGCCTGTGAGGCAGATGTCAACGTGCAAGATGATGACGGCTCCACGGCC
CTCATGTGCGCCTGTGAGCACGGCCACAAGGAGATCGCGGGGCTGCTGCTGGCCGTGCCCAGCTGTGACATCTCACTCACAGATCGCGAT
GGGAGCACAGCTCTGATGGTGGCCTTGGACGCAGGGCAGAGTGAGATTGCGTCCATGCTGTATTCCCGCATGAACATCAAGTGCTCGTTT
GCCCCAATGTCAGATGACGAGAGCCCTACATCATCCTCGGCAGAAGAGTAGCCGTGAGGGAGGCGGGGACCAGCCAGACCGGGAGCAAAC
CGTCCCTTGTCCCCGTCTCCTCCCTGTTCCCGTTCCTCCCTGGCCCACCCCACTCACACTCCCCAAGGCCCACGGCTCAAAGGCAAGCGA
GCTCTCCCTCTGCTTCCCTGGGGGAGCCCCGACGGCCACAGGACTCCAGCTCCAAGTGGGTTTTCTTGGCTCCCCTGTTCAAAGTGGCCA
CAGCGCAGACCGAAGCAAAATTCTTGTATACATTGGCGCCAGGGCTGATGCTGGGGTGTGGGTTTTATGAAGAACATTGAGAACAATCAG
CTGGTAATTATGGATGGAGGAAGAGGGAGAGGAAAAAAATATTGTATTTTTGAATCATTGTTGCAGGAGGGGGTGGGAATCTTAGGATTT
GTTGCCAGATTTGAAAGTCACTGGAACTTGCATATTTTCATTTTAATCCTAAGTGTTATTACGCACCAGTTGGGGTTCACCCTTCATCCC
CCACATTTAATTGTCTGATATAGAATAGTGTTGTGTCCACTGCCCCGCTAGACGGCTTTCTTAGGGGAATTTTCTTCTGGTTGTTTCACA
AGACAGATTCTGTCCTTGTCACCCGGGACAGAAAACTCAGTCTTTTCACCCTCATTCAGATGAAGGGACTCAGGACAGGCTCTGTGACTT
ACAGGGACCCAATCAATTCACAATGAGAAATTACCGGCCAGGCGTGGTGACTCACGTCTGTAATCCCAGCACTTTGGGAGGGCAAGGCAA
GAGCTTGAGCTTGAGCCTAGACGTTAAAGACCAGCCTGGGCAACACAGCAAGACCCATCTCTACAAGAAATTTAAAAACTAGCCAGGCGT
GGTGGTGCGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGCCCTGGAGGTCGAGGCTACAGTGAGCTATGATCACACCATTGCACTTCA
GCCTGGGCGACACAGCGAGACCCTGTCTCAAGAAAGAAAAGAAAAAGAGACAAATTACCCAGAAACCCCTCCCTTCCCCACATGGAGGCC
TTGGCAAATGTTAATTTTCCTAGAAAATCCTTCAGACCTGAAGACGCAGGAAAAGAATCTGGCTCTCAGGGTGGCTTCTGCGTCCCCGCC
GCCAGGCCCCAGACTATGGTCACAGGGCCGTCCTGTTCCTCCCCGGGACTCCAGAATTTCTCTCCTCAAAGGAAAGAAAACAGGGCATGC
GCTTGTTGGCAAAACGCAGGGCCGGCTCCCAAAAACCCCATGTGTGTACGATTAAAAGTTGGCCGTCCCCAGGCCTCCCAGCGCAAACTT
CAAGAGACAGGGCTTTGCTGAAAACCAAACATGGGCCAGCTGGGCTTTTTAACAACCTAGAGACTTTCCGGAGCTGCCTGGAACAGAGCC
TGCGGGAAACGGGGCTTGCCAGAGACACTCACAGTTTCCTTCATGGCCTGTTTTGGTCCCCTAAGAATCTCCACATCATTGTCTTTCTTG
TGCCTTTTCCTTGGTGAGCAACAGAAAGGGAAGGGTTCCAAGCCTCTAAAAATGTGCTTTGTGATCAGGAGTGCGCTCCAAACCAAATAC
GCGCGCTGCCCTTTCGAGGCCAGTGAGCTCAGCCTCCAAGGCTTTAAAGCCACATTTCAGCAAGAGAAAGCGCTGAGAGCTCGCAGGTTC
ATTAAAGAAGGCAAAGCACTGGTTTCTCTCCTTAGAAAAGTAGGTTTCTTGGCTTGATGTAGACTGGCTTGCTTTGATTTTTAGTGAAGG
GAATGTACGTAAAACAAAATAGGGCTTGGCTGGTCAAAGGAGACAAGCAGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATG
GATGGATGAATAGATAGATGGTGTTTGCATGTAAATTGCAGAGAAAACAAAACCAAAGCTGATTGGAAACAATTAATTGTGGGTGTCTGA
GGGGGAAGGTCGCAGCTTTGGGCAGCTTTGAGAAGCGGTACAAGAGTTCTGTGCCTGTGTGTCCAGCCCTGGAGCCAGCCAGTGCATTTA
TTTTAAGCTCTTAGAAGCAACTCCTTGGCCCAGGAATGCGTGACCCCTGAGATGGGTCCACGCATCTCTCTACACTTCCTTCTCTCCGTG
GGATACTGGACTCGTGCCTCTGCGCCCATTCTCTTCTCACGCATATCCATGAGCTTTAATTTCACTTTCTGATCACGGTACGTCCATAAA
GCCAGTATTACACTTAAATGAAGTATTCTTTTTTGTAATCGTTTTTTTTAGAAGGTAAACAAATTTAATAAAGCTACCAATAATGTTGAT
G

>10822_10822_7_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000539026_KANK2_chr19_11289396_ENST00000355150_length(amino acids)=453AA_BP=18
MTQISCSLTCLEGLRGCGGLPEVPAESSSSPPGSEVASLTQPEKSTGRVPTQEPTHREPTRQAASQESEEAGGTGGPPAGVRSIMKRKEE
VADPTAHRRSLQFVGVNGGYESSSEDSSTAENISDNDSTENEAPEPRERVPSVAEAPQLRPAGTAAAKTSRQECQLSRESQHIPTAEGAS
GSNTEEEIRMELSPDLISACLALEKYLDNPNALTERELKVAYTTVLQEWLRLACRSDAHPELVRRHLVTFRAMSARLLDYVVNIADSNGN
TALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIETVLQLFRLGNINAKASQAGQTALMLAVSHGRVDVVKAL
LACEADVNVQDDDGSTALMCACEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNIKCSFAPMSDDESPTSSS
AEE

--------------------------------------------------------------
>10822_10822_8_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000539026_KANK2_chr19_11289396_ENST00000432929_length(transcript)=3985nt_BP=364nt
AAATTTGTTGGCTGCTTGAGCTGGGATATTCATCTTTCTCCTGATCTTGGACATCAGAACTCCTGATTCTCAAGCCTTTGGGTTTGGACT
GGAGGCACCAGCTTTCCTGGGCCTCCAGCTTGCAGATGGCATATCATGGAACTTCTCAGCCTCCAAATTCATAACTCTAATACACCAGTA
CAATGGAAAGATTCCTAAATTCAAAAGCCAGAAGGCTGGGTTCCTGTTCCCACCCTGCCTTTTACCTTCTGTGTGTTCCTGATGAAGACA
CTTCATGCTCCACTATTTACTTACCTCTGAAACGAAGGGCTGACCCAGATCAGTTGTTCTCTGACCTGCTTGGAGGGACTCAGAGGCTGT
GGAGGCCTCCCAGAAGTTCCTGCCGAATCGTCTTCGTCACCCCCGGGGTCCGAGGTAGCCTCCCTTACACAGCCTGAGAAGAGCACAGGC
CGAGTGCCCACCCAGGAGCCCACCCACAGGGAGCCCACCAGGCAAGCAGCCTCCCAAGAGTCCGAGGAGGCCGGGGGCACCGCACCTCCG
CTGTCCTCCCCTCCAGGCGGGCCCCCGGCAGGCGTGCGATCTATCATGAAACGGAAAGAGGAGGTTGCAGACCCCACGGCCCACCGGAGG
AGCCTCCAGTTCGTGGGGGTCAACGGCGGGTATGAGTCGTCATCCGAGGACTCCAGCACAGCAGAGAACATCTCAGACAACGACAGCACA
GAGAACGAGGCCCCAGAGCCGAGGGAGAGGGTTCCGAGTGTGGCCGAAGCCCCCCAGCTCAGGCCTGCAGGGACGGCAGCGGCCAAGACC
AGCCGGCAGGAGTGTCAGCTGTCTCGAGAATCTCAGCACATACCCACTGCTGAGGGGGCATCAGGATCAAACACGGAGGAGGAGATCAGG
ATGGAGCTAAGCCCTGACCTCATCTCAGCCTGCTTGGCCCTGGAAAAGTACCTGGACAATCCCAACGCCCTCACAGAGCGGGAGCTGAAA
GTGGCCTACACCACAGTGCTGCAGGAGTGGCTGCGCCTGGCCTGCCGCAGCGACGCACACCCCGAGCTGGTGCGGCGGCACCTGGTCACG
TTCCGGGCCATGTCTGCGCGGCTGCTGGACTACGTGGTCAACATCGCCGACAGCAACGGCAACACAGCCCTGCACTACTCCGTGTCTCAT
GCCAACTTCCCCGTGGTGCAGCAGCTGCTCGACAGCGGTGTCTGCAAGGTGGACAAACAGAACCGTGCTGGCTACAGCCCTATTATGCTC
ACCGCCCTGGCCACCCTGAAGACCCAGGACGACATCGAGACTGTCCTTCAGCTCTTCCGGCTTGGCAACATCAATGCCAAAGCCAGCCAG
GCAGGACAGACGGCCCTGATGCTGGCCGTCAGCCACGGGCGGGTGGACGTTGTCAAAGCCCTGCTGGCCTGTGAGGCAGATGTCAACGTG
CAAGATGATGACGGCTCCACGGCCCTCATGTGCGCCTGTGAGCACGGCCACAAGGAGATCGCGGGGCTGCTGCTGGCCGTGCCCAGCTGT
GACATCTCACTCACAGATCGCGATGGGAGCACAGCTCTGATGGTGGCCTTGGACGCAGGGCAGAGTGAGATTGCGTCCATGCTGTATTCC
CGCATGAACATCAAGTGCTCGTTTGCCCCAATGTCAGATGACGAGAGCCCTACATCATCCTCGGCAGAAGAGTAGCCGTGAGGGAGGCGG
GGACCAGCCAGACCGGGAGCAAACCGTCCCTTGTCCCCGTCTCCTCCCTGTTCCCGTTCCTCCCTGGCCCACCCCACTCACACTCCCCAA
GGCCCACGGCTCAAAGGCAAGCGAGCTCTCCCTCTGCTTCCCTGGGGGAGCCCCGACGGCCACAGGACTCCAGCTCCAAGTGGGTTTTCT
TGGCTCCCCTGTTCAAAGTGGCCACAGCGCAGACCGAAGCAAAATTCTTGTATACATTGGCGCCAGGGCTGATGCTGGGGTGTGGGTTTT
ATGAAGAACATTGAGAACAATCAGCTGGTAATTATGGATGGAGGAAGAGGGAGAGGAAAAAAATATTGTATTTTTGAATCATTGTTGCAG
GAGGGGGTGGGAATCTTAGGATTTGTTGCCAGATTTGAAAGTCACTGGAACTTGCATATTTTCATTTTAATCCTAAGTGTTATTACGCAC
CAGTTGGGGTTCACCCTTCATCCCCCACATTTAATTGTCTGATATAGAATAGTGTTGTGTCCACTGCCCCGCTAGACGGCTTTCTTAGGG
GAATTTTCTTCTGGTTGTTTCACAAGACAGATTCTGTCCTTGTCACCCGGGACAGAAAACTCAGTCTTTTCACCCTCATTCAGATGAAGG
GACTCAGGACAGGCTCTGTGACTTACAGGGACCCAATCAATTCACAATGAGAAATTACCGGCCAGGCGTGGTGACTCACGTCTGTAATCC
CAGCACTTTGGGAGGGCAAGGCAAGAGCTTGAGCTTGAGCCTAGACGTTAAAGACCAGCCTGGGCAACACAGCAAGACCCATCTCTACAA
GAAATTTAAAAACTAGCCAGGCGTGGTGGTGCGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGCCCTGGAGGTCGAGGCTACAGTGAG
CTATGATCACACCATTGCACTTCAGCCTGGGCGACACAGCGAGACCCTGTCTCAAGAAAGAAAAGAAAAAGAGACAAATTACCCAGAAAC
CCCTCCCTTCCCCACATGGAGGCCTTGGCAAATGTTAATTTTCCTAGAAAATCCTTCAGACCTGAAGACGCAGGAAAAGAATCTGGCTCT
CAGGGTGGCTTCTGCGTCCCCGCCGCCAGGCCCCAGACTATGGTCACAGGGCCGTCCTGTTCCTCCCCGGGACTCCAGAATTTCTCTCCT
CAAAGGAAAGAAAACAGGGCATGCGCTTGTTGGCAAAACGCAGGGCCGGCTCCCAAAAACCCCATGTGTGTACGATTAAAAGTTGGCCGT
CCCCAGGCCTCCCAGCGCAAACTTCAAGAGACAGGGCTTTGCTGAAAACCAAACATGGGCCAGCTGGGCTTTTTAACAACCTAGAGACTT
TCCGGAGCTGCCTGGAACAGAGCCTGCGGGAAACGGGGCTTGCCAGAGACACTCACAGTTTCCTTCATGGCCTGTTTTGGTCCCCTAAGA
ATCTCCACATCATTGTCTTTCTTGTGCCTTTTCCTTGGTGAGCAACAGAAAGGGAAGGGTTCCAAGCCTCTAAAAATGTGCTTTGTGATC
AGGAGTGCGCTCCAAACCAAATACGCGCGCTGCCCTTTCGAGGCCAGTGAGCTCAGCCTCCAAGGCTTTAAAGCCACATTTCAGCAAGAG
AAAGCGCTGAGAGCTCGCAGGTTCATTAAAGAAGGCAAAGCACTGGTTTCTCTCCTTAGAAAAGTAGGTTTCTTGGCTTGATGTAGACTG
GCTTGCTTTGATTTTTAGTGAAGGGAATGTACGTAAAACAAAATAGGGCTTGGCTGGTCAAAGGAGACAAGCAGGATGGATGGATGGATG
GATGGATGGATGGATGGATGGATGGATGGATGAATAGATAGATGGTGTTTGCATGTAAATTGCAGAGAAAACAAAACCAAAGCTGATTGG
AAACAATTAATTGTGGGTGTCTGAGGGGGAAGGTCGCAGCTTTGGGCAGCTTTGAGAAGCGGTACAAGAGTTCTGTGCCTGTGTGTCCAG
CCCTGGAGCCAGCCAGTGCATTTATTTTAAGCTCTTAGAAGCAACTCCTTGGCCCAGGAATGCGTGACCCCTGAGATGGGTCCACGCATC
TCTCTACACTTCCTTCTCTCCGTGGGATACTGGACTCGTGCCTCTGCGCCCATTCTCTTCTCACGCATATCCATGAGCTTTAATTTCACT
TTCTGATCACGGTACGTCCATAAAGCCAGTATTACACTTAAATGAAGTATTCTTTTTTGTAATCGTTTTTTTTAGAAGGTAAACAAATTT
AATAAAGCTACCAATAATGTTGATG

>10822_10822_8_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000539026_KANK2_chr19_11289396_ENST00000432929_length(amino acids)=461AA_BP=18
MTQISCSLTCLEGLRGCGGLPEVPAESSSSPPGSEVASLTQPEKSTGRVPTQEPTHREPTRQAASQESEEAGGTAPPLSSPPGGPPAGVR
SIMKRKEEVADPTAHRRSLQFVGVNGGYESSSEDSSTAENISDNDSTENEAPEPRERVPSVAEAPQLRPAGTAAAKTSRQECQLSRESQH
IPTAEGASGSNTEEEIRMELSPDLISACLALEKYLDNPNALTERELKVAYTTVLQEWLRLACRSDAHPELVRRHLVTFRAMSARLLDYVV
NIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIETVLQLFRLGNINAKASQAGQTALMLAVSHG
RVDVVKALLACEADVNVQDDDGSTALMCACEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNIKCSFAPMSD
DESPTSSSAEE

--------------------------------------------------------------
>10822_10822_9_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000539026_KANK2_chr19_11289396_ENST00000586659_length(transcript)=3962nt_BP=364nt
AAATTTGTTGGCTGCTTGAGCTGGGATATTCATCTTTCTCCTGATCTTGGACATCAGAACTCCTGATTCTCAAGCCTTTGGGTTTGGACT
GGAGGCACCAGCTTTCCTGGGCCTCCAGCTTGCAGATGGCATATCATGGAACTTCTCAGCCTCCAAATTCATAACTCTAATACACCAGTA
CAATGGAAAGATTCCTAAATTCAAAAGCCAGAAGGCTGGGTTCCTGTTCCCACCCTGCCTTTTACCTTCTGTGTGTTCCTGATGAAGACA
CTTCATGCTCCACTATTTACTTACCTCTGAAACGAAGGGCTGACCCAGATCAGTTGTTCTCTGACCTGCTTGGAGGGACTCAGAGGCTGT
GGAGGCCTCCCAGAAGTTCCTGCCGAATCGTCTTCGTCACCCCCGGGGTCCGAGGTAGCCTCCCTTACACAGCCTGAGAAGAGCACAGGC
CGAGTGCCCACCCAGGAGCCCACCCACAGGGAGCCCACCAGGCAAGCAGCCTCCCAAGAGTCCGAGGAGGCCGGGGGCACCGGCGGGCCC
CCGGCAGGCGTGCGATCTATCATGAAACGGAAAGAGGAGGTTGCAGACCCCACGGCCCACCGGAGGAGCCTCCAGTTCGTGGGGGTCAAC
GGCGGGTATGAGTCGTCATCCGAGGACTCCAGCACAGCAGAGAACATCTCAGACAACGACAGCACAGAGAACGAGGCCCCAGAGCCGAGG
GAGAGGGTTCCGAGTGTGGCCGAAGCCCCCCAGCTCAGGCCTGCAGGGACGGCAGCGGCCAAGACCAGCCGGCAGGAGTGTCAGCTGTCT
CGAGAATCTCAGCACATACCCACTGCTGAGGGGGCATCAGGATCAAACACGGAGGAGGAGATCAGGATGGAGCTAAGCCCTGACCTCATC
TCAGCCTGCTTGGCCCTGGAAAAGTACCTGGACAATCCCAACGCCCTCACAGAGCGGGAGCTGAAAGTGGCCTACACCACAGTGCTGCAG
GAGTGGCTGCGCCTGGCCTGCCGCAGCGACGCACACCCCGAGCTGGTGCGGCGGCACCTGGTCACGTTCCGGGCCATGTCTGCGCGGCTG
CTGGACTACGTGGTCAACATCGCCGACAGCAACGGCAACACAGCCCTGCACTACTCCGTGTCTCATGCCAACTTCCCCGTGGTGCAGCAG
CTGCTCGACAGCGGTGTCTGCAAGGTGGACAAACAGAACCGTGCTGGCTACAGCCCTATTATGCTCACCGCCCTGGCCACCCTGAAGACC
CAGGACGACATCGAGACTGTCCTTCAGCTCTTCCGGCTTGGCAACATCAATGCCAAAGCCAGCCAGGCAGGACAGACGGCCCTGATGCTG
GCCGTCAGCCACGGGCGGGTGGACGTTGTCAAAGCCCTGCTGGCCTGTGAGGCAGATGTCAACGTGCAAGATGATGACGGCTCCACGGCC
CTCATGTGCGCCTGTGAGCACGGCCACAAGGAGATCGCGGGGCTGCTGCTGGCCGTGCCCAGCTGTGACATCTCACTCACAGATCGCGAT
GGGAGCACAGCTCTGATGGTGGCCTTGGACGCAGGGCAGAGTGAGATTGCGTCCATGCTGTATTCCCGCATGAACATCAAGTGCTCGTTT
GCCCCAATGTCAGATGACGAGAGCCCTACATCATCCTCGGCAGAAGAGTAGCCGTGAGGGAGGCGGGGACCAGCCAGACCGGGAGCAAAC
CGTCCCTTGTCCCCGTCTCCTCCCTGTTCCCGTTCCTCCCTGGCCCACCCCACTCACACTCCCCAAGGCCCACGGCTCAAAGGCAAGCGA
GCTCTCCCTCTGCTTCCCTGGGGGAGCCCCGACGGCCACAGGACTCCAGCTCCAAGTGGGTTTTCTTGGCTCCCCTGTTCAAAGTGGCCA
CAGCGCAGACCGAAGCAAAATTCTTGTATACATTGGCGCCAGGGCTGATGCTGGGGTGTGGGTTTTATGAAGAACATTGAGAACAATCAG
CTGGTAATTATGGATGGAGGAAGAGGGAGAGGAAAAAAATATTGTATTTTTGAATCATTGTTGCAGGAGGGGGTGGGAATCTTAGGATTT
GTTGCCAGATTTGAAAGTCACTGGAACTTGCATATTTTCATTTTAATCCTAAGTGTTATTACGCACCAGTTGGGGTTCACCCTTCATCCC
CCACATTTAATTGTCTGATATAGAATAGTGTTGTGTCCACTGCCCCGCTAGACGGCTTTCTTAGGGGAATTTTCTTCTGGTTGTTTCACA
AGACAGATTCTGTCCTTGTCACCCGGGACAGAAAACTCAGTCTTTTCACCCTCATTCAGATGAAGGGACTCAGGACAGGCTCTGTGACTT
ACAGGGACCCAATCAATTCACAATGAGAAATTACCGGCCAGGCGTGGTGACTCACGTCTGTAATCCCAGCACTTTGGGAGGGCAAGGCAA
GAGCTTGAGCTTGAGCCTAGACGTTAAAGACCAGCCTGGGCAACACAGCAAGACCCATCTCTACAAGAAATTTAAAAACTAGCCAGGCGT
GGTGGTGCGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGCCCTGGAGGTCGAGGCTACAGTGAGCTATGATCACACCATTGCACTTCA
GCCTGGGCGACACAGCGAGACCCTGTCTCAAGAAAGAAAAGAAAAAGAGACAAATTACCCAGAAACCCCTCCCTTCCCCACATGGAGGCC
TTGGCAAATGTTAATTTTCCTAGAAAATCCTTCAGACCTGAAGACGCAGGAAAAGAATCTGGCTCTCAGGGTGGCTTCTGCGTCCCCGCC
GCCAGGCCCCAGACTATGGTCACAGGGCCGTCCTGTTCCTCCCCGGGACTCCAGAATTTCTCTCCTCAAAGGAAAGAAAACAGGGCATGC
GCTTGTTGGCAAAACGCAGGGCCGGCTCCCAAAAACCCCATGTGTGTACGATTAAAAGTTGGCCGTCCCCAGGCCTCCCAGCGCAAACTT
CAAGAGACAGGGCTTTGCTGAAAACCAAACATGGGCCAGCTGGGCTTTTTAACAACCTAGAGACTTTCCGGAGCTGCCTGGAACAGAGCC
TGCGGGAAACGGGGCTTGCCAGAGACACTCACAGTTTCCTTCATGGCCTGTTTTGGTCCCCTAAGAATCTCCACATCATTGTCTTTCTTG
TGCCTTTTCCTTGGTGAGCAACAGAAAGGGAAGGGTTCCAAGCCTCTAAAAATGTGCTTTGTGATCAGGAGTGCGCTCCAAACCAAATAC
GCGCGCTGCCCTTTCGAGGCCAGTGAGCTCAGCCTCCAAGGCTTTAAAGCCACATTTCAGCAAGAGAAAGCGCTGAGAGCTCGCAGGTTC
ATTAAAGAAGGCAAAGCACTGGTTTCTCTCCTTAGAAAAGTAGGTTTCTTGGCTTGATGTAGACTGGCTTGCTTTGATTTTTAGTGAAGG
GAATGTACGTAAAACAAAATAGGGCTTGGCTGGTCAAAGGAGACAAGCAGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATG
GATGGATGAATAGATAGATGGTGTTTGCATGTAAATTGCAGAGAAAACAAAACCAAAGCTGATTGGAAACAATTAATTGTGGGTGTCTGA
GGGGGAAGGTCGCAGCTTTGGGCAGCTTTGAGAAGCGGTACAAGAGTTCTGTGCCTGTGTGTCCAGCCCTGGAGCCAGCCAGTGCATTTA
TTTTAAGCTCTTAGAAGCAACTCCTTGGCCCAGGAATGCGTGACCCCTGAGATGGGTCCACGCATCTCTCTACACTTCCTTCTCTCCGTG
GGATACTGGACTCGTGCCTCTGCGCCCATTCTCTTCTCACGCATATCCATGAGCTTTAATTTCACTTTCTGATCACGGTACGTCCATAAA
GCCAGTATTACACTTAAATGAAGTATTCTTTTTTGTAATCGTTTTTTTTAGAAGGTAAACAAATTTAATAAAGCTACCAATAATGTTGAT
GA

>10822_10822_9_C12orf36-KANK2_C12orf36_chr12_13529157_ENST00000539026_KANK2_chr19_11289396_ENST00000586659_length(amino acids)=453AA_BP=18
MTQISCSLTCLEGLRGCGGLPEVPAESSSSPPGSEVASLTQPEKSTGRVPTQEPTHREPTRQAASQESEEAGGTGGPPAGVRSIMKRKEE
VADPTAHRRSLQFVGVNGGYESSSEDSSTAENISDNDSTENEAPEPRERVPSVAEAPQLRPAGTAAAKTSRQECQLSRESQHIPTAEGAS
GSNTEEEIRMELSPDLISACLALEKYLDNPNALTERELKVAYTTVLQEWLRLACRSDAHPELVRRHLVTFRAMSARLLDYVVNIADSNGN
TALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIETVLQLFRLGNINAKASQAGQTALMLAVSHGRVDVVKAL
LACEADVNVQDDDGSTALMCACEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNIKCSFAPMSDDESPTSSS
AEE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for C12orf36-KANK2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneKANK2chr12:13529157chr19:11289396ENST00000355150111669_835416.3333333333333852.0NCOA1
TgeneKANK2chr12:13529157chr19:11289396ENST00000432929313669_835416.3333333333333860.0NCOA1
TgeneKANK2chr12:13529157chr19:11289396ENST00000586659313669_835416.3333333333333852.0NCOA1
TgeneKANK2chr12:13529157chr19:11289396ENST00000589359313669_835416.3333333333333860.0NCOA1
TgeneKANK2chr12:13529157chr19:11289396ENST00000589894110669_835416.3333333333333842.0NCOA1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneKANK2chr12:13529157chr19:11289396ENST000003551501111_72416.3333333333333852.0AIFM1
TgeneKANK2chr12:13529157chr19:11289396ENST000004329293131_72416.3333333333333860.0AIFM1
TgeneKANK2chr12:13529157chr19:11289396ENST000005866593131_72416.3333333333333852.0AIFM1
TgeneKANK2chr12:13529157chr19:11289396ENST000005893593131_72416.3333333333333860.0AIFM1
TgeneKANK2chr12:13529157chr19:11289396ENST000005898941101_72416.3333333333333842.0AIFM1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for C12orf36-KANK2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for C12orf36-KANK2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC1135196Heart Failure, Diastolic1CTD_human
TgeneC4015202PALMOPLANTAR KERATODERMA AND WOOLLY HAIR1CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC4540453NEPHROTIC SYNDROME, TYPE 161GENOMICS_ENGLAND;UNIPROT