Fusion Gene Studies
in Kim Lab

FusionBase FusionGDB FusionGDB2 FusionPDB FusionNeoAntigen FusionAI FusionNW FGviewer Publication Contact
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact

Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:ENDOV-SLC26A11 (FusionGDB2 ID:HG284131TG284129)

Fusion Gene Summary for ENDOV-SLC26A11

check button Fusion gene summary
Fusion gene informationFusion gene name: ENDOV-SLC26A11
Fusion gene ID: hg284131tg284129
HgeneTgene
Gene symbol

ENDOV

SLC26A11

Gene ID

284131

284129

Gene nameendonuclease Vsolute carrier family 26 member 11
Synonyms--
Cytomap('ENDOV')('SLC26A11')

17q25.3

17q25.3

Type of geneprotein-codingprotein-coding
Descriptionendonuclease VhEndoVinosine-specific endoribonucleasesodium-independent sulfate anion transportersolute carrier family 26 (anion exchanger), member 11
Modification date2020031320200313
UniProtAcc

Q8N8Q3

.
Ensembl transtripts involved in fusion geneENST00000521847, ENST00000323854, 
ENST00000518137, ENST00000520367, 
ENST00000523999, ENST00000517295, 
ENST00000517795, ENST00000518644, 
ENST00000518901, ENST00000518907, 
ENST00000520284, ENST00000522751, 
Fusion gene scores* DoF score4 X 4 X 3=486 X 7 X 7=294
# samples 49
** MAII scorelog2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(9/294*10)=-1.70781924850669
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ENDOV [Title/Abstract] AND SLC26A11 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointENDOV(78389410)-SLC26A11(78210727), # samples:1
ENDOV(78389621)-SLC26A11(78210727), # samples:1
Anticipated loss of major functional domain due to fusion event.ENDOV-SLC26A11 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSLC26A11

GO:0008272

sulfate transport

12626430



check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-C8-A135-01AENDOVchr17

78389410

+SLC26A11chr17

78210727

+
ChimerDB4BRCATCGA-C8-A135-01AENDOVchr17

78389621

-SLC26A11chr17

78210727

+


Top

Fusion Gene ORF analysis for ENDOV-SLC26A11

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000521847ENST00000361193ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
3UTR-3CDSENST00000521847ENST00000361193ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
3UTR-3CDSENST00000521847ENST00000411502ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
3UTR-3CDSENST00000521847ENST00000411502ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
3UTR-3CDSENST00000521847ENST00000546047ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
3UTR-3CDSENST00000521847ENST00000546047ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
3UTR-intronENST00000521847ENST00000571602ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
3UTR-intronENST00000521847ENST00000571602ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
3UTR-intronENST00000521847ENST00000572725ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
3UTR-intronENST00000521847ENST00000572725ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5CDS-intronENST00000323854ENST00000571602ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5CDS-intronENST00000323854ENST00000572725ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5CDS-intronENST00000518137ENST00000571602ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5CDS-intronENST00000518137ENST00000572725ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5CDS-intronENST00000520367ENST00000571602ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5CDS-intronENST00000520367ENST00000572725ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5CDS-intronENST00000523999ENST00000571602ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5CDS-intronENST00000523999ENST00000572725ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-3CDSENST00000517295ENST00000361193ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-3CDSENST00000517295ENST00000411502ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-3CDSENST00000517295ENST00000546047ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-3CDSENST00000517795ENST00000361193ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-3CDSENST00000517795ENST00000411502ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-3CDSENST00000517795ENST00000546047ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-3CDSENST00000518644ENST00000361193ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-3CDSENST00000518644ENST00000411502ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-3CDSENST00000518644ENST00000546047ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-3CDSENST00000518901ENST00000361193ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-3CDSENST00000518901ENST00000411502ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-3CDSENST00000518901ENST00000546047ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-3CDSENST00000518907ENST00000361193ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-3CDSENST00000518907ENST00000411502ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-3CDSENST00000518907ENST00000546047ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-3CDSENST00000520284ENST00000361193ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-3CDSENST00000520284ENST00000411502ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-3CDSENST00000520284ENST00000546047ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-3CDSENST00000522751ENST00000361193ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-3CDSENST00000522751ENST00000361193ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-3CDSENST00000522751ENST00000411502ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-3CDSENST00000522751ENST00000411502ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-3CDSENST00000522751ENST00000546047ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-3CDSENST00000522751ENST00000546047ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-intronENST00000517295ENST00000571602ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-intronENST00000517295ENST00000572725ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-intronENST00000517795ENST00000571602ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-intronENST00000517795ENST00000572725ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-intronENST00000518644ENST00000571602ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-intronENST00000518644ENST00000572725ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-intronENST00000518901ENST00000571602ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-intronENST00000518901ENST00000572725ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-intronENST00000518907ENST00000571602ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-intronENST00000518907ENST00000572725ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-intronENST00000520284ENST00000571602ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-intronENST00000520284ENST00000572725ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-intronENST00000522751ENST00000571602ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-intronENST00000522751ENST00000571602ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
5UTR-intronENST00000522751ENST00000572725ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
5UTR-intronENST00000522751ENST00000572725ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
Frame-shiftENST00000323854ENST00000361193ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
Frame-shiftENST00000323854ENST00000411502ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
Frame-shiftENST00000323854ENST00000546047ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
Frame-shiftENST00000518137ENST00000361193ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
Frame-shiftENST00000518137ENST00000411502ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
Frame-shiftENST00000518137ENST00000546047ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
Frame-shiftENST00000520367ENST00000361193ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
Frame-shiftENST00000520367ENST00000411502ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
Frame-shiftENST00000520367ENST00000546047ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
Frame-shiftENST00000523999ENST00000361193ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
Frame-shiftENST00000523999ENST00000411502ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
Frame-shiftENST00000523999ENST00000546047ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
intron-3CDSENST00000323854ENST00000361193ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000323854ENST00000411502ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000323854ENST00000546047ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000517295ENST00000361193ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000517295ENST00000411502ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000517295ENST00000546047ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000517795ENST00000361193ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
intron-3CDSENST00000517795ENST00000411502ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
intron-3CDSENST00000517795ENST00000546047ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
intron-3CDSENST00000518137ENST00000361193ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000518137ENST00000411502ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000518137ENST00000546047ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000518644ENST00000361193ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000518644ENST00000411502ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000518644ENST00000546047ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000518901ENST00000361193ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
intron-3CDSENST00000518901ENST00000411502ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
intron-3CDSENST00000518901ENST00000546047ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
intron-3CDSENST00000518907ENST00000361193ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
intron-3CDSENST00000518907ENST00000411502ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
intron-3CDSENST00000518907ENST00000546047ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
intron-3CDSENST00000520284ENST00000361193ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000520284ENST00000411502ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000520284ENST00000546047ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000520367ENST00000361193ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000520367ENST00000411502ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000520367ENST00000546047ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000523999ENST00000361193ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000523999ENST00000411502ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-3CDSENST00000523999ENST00000546047ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-intronENST00000323854ENST00000571602ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-intronENST00000323854ENST00000572725ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-intronENST00000517295ENST00000571602ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-intronENST00000517295ENST00000572725ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-intronENST00000517795ENST00000571602ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
intron-intronENST00000517795ENST00000572725ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
intron-intronENST00000518137ENST00000571602ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-intronENST00000518137ENST00000572725ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-intronENST00000518644ENST00000571602ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-intronENST00000518644ENST00000572725ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-intronENST00000518901ENST00000571602ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
intron-intronENST00000518901ENST00000572725ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
intron-intronENST00000518907ENST00000571602ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
intron-intronENST00000518907ENST00000572725ENDOVchr17

78389621

-SLC26A11chr17

78210727

+
intron-intronENST00000520284ENST00000571602ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-intronENST00000520284ENST00000572725ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-intronENST00000520367ENST00000571602ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-intronENST00000520367ENST00000572725ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-intronENST00000523999ENST00000571602ENDOVchr17

78389410

+SLC26A11chr17

78210727

+
intron-intronENST00000523999ENST00000572725ENDOVchr17

78389410

+SLC26A11chr17

78210727

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

Top

Fusion Genomic Features for ENDOV-SLC26A11


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ENDOVchr1778389410+SLC26A11chr1778210726+0.009910240.9900898
ENDOVchr1778389410+SLC26A11chr1778210726+0.009910240.9900898


check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for ENDOV-SLC26A11


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:78389410/:78210727)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ENDOV

Q8N8Q3

.
FUNCTION: [Isoform 1]: Endoribonuclease that specifically cleaves inosine-containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine (PubMed:23912683, PubMed:23912718, PubMed:27573237, PubMed:31703097, PubMed:25195743). Active against both single-stranded and double-stranded RNAs (PubMed:31703097, PubMed:25195743). Has strong preference for single-stranded RNAs (ssRNAs) toward double-stranded RNAs (dsRNAs) (PubMed:23912718). Cleaves mRNAs and tRNAs containing inosine (PubMed:23912683, PubMed:31703097). Also able to cleave structure-specific dsRNA substrates containing the specific sites 5'-IIUI-3' and 5'-UIUU-3' (PubMed:23912718, PubMed:27573237). Inosine is present in a number of RNAs following editing; the function of inosine-specific endoribonuclease is still unclear: it could either play a regulatory role in edited RNAs, or be involved in antiviral response by removing the hyperedited long viral dsRNA genome that has undergone A-to-I editing (Probable). Binds branched DNA structures (PubMed:23139746). {ECO:0000269|PubMed:23139746, ECO:0000269|PubMed:23912683, ECO:0000269|PubMed:23912718, ECO:0000269|PubMed:25195743, ECO:0000269|PubMed:27573237, ECO:0000269|PubMed:31703097, ECO:0000305}.; FUNCTION: [Isoform 6]: Endoribonuclease that specifically cleaves inosine-containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine (PubMed:31703097). Active against both single-stranded and double-stranded RNAs (PubMed:31703097). Cleaves tRNAs containing inosine (PubMed:31703097). {ECO:0000269|PubMed:31703097}.; FUNCTION: [Isoform 7]: Endoribonuclease that specifically cleaves inosine-containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine (PubMed:31703097). Active against both single-stranded and double-stranded RNAs (PubMed:31703097). Cleaves tRNAs containing inosine (PubMed:31703097). {ECO:0000269|PubMed:31703097}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

Fusion Gene Sequence for ENDOV-SLC26A11


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

Top

Fusion Gene PPI Analysis for ENDOV-SLC26A11


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for ENDOV-SLC26A11


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for ENDOV-SLC26A11


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource