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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CCDC113-CPNE2 (FusionGDB2 ID:HG29070TG221184)

Fusion Gene Summary for CCDC113-CPNE2

check button Fusion gene summary
Fusion gene informationFusion gene name: CCDC113-CPNE2
Fusion gene ID: hg29070tg221184
HgeneTgene
Gene symbol

CCDC113

CPNE2

Gene ID

29070

221184

Gene namecoiled-coil domain containing 113copine 2
SynonymsHSPC065COPN2|CPN2
Cytomap('CCDC113')('CPNE2')

16q21

16q13

Type of geneprotein-codingprotein-coding
Descriptioncoiled-coil domain-containing protein 113copine-2copine II
Modification date2020031320200313
UniProtAcc.

Q96FN4

Ensembl transtripts involved in fusion geneENST00000219299, ENST00000443128, 
ENST00000566498, 
Fusion gene scores* DoF score3 X 3 X 2=185 X 4 X 3=60
# samples 35
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(5/60*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CCDC113 [Title/Abstract] AND CPNE2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCCDC113(58301490)-CPNE2(57179997), # samples:3
Anticipated loss of major functional domain due to fusion event.CCDC113-CPNE2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CCDC113-CPNE2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CCDC113 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CPNE2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4CESCTCGA-EK-A2PM-01ACCDC113chr16

58301490

-CPNE2chr16

57179997

+
ChimerDB4CESCTCGA-EK-A2PM-01ACCDC113chr16

58301490

+CPNE2chr16

57179997

+


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Fusion Gene ORF analysis for CCDC113-CPNE2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000219299ENST00000565951CCDC113chr16

58301490

+CPNE2chr16

57179997

+
5CDS-3UTRENST00000443128ENST00000565951CCDC113chr16

58301490

+CPNE2chr16

57179997

+
In-frameENST00000219299ENST00000290776CCDC113chr16

58301490

+CPNE2chr16

57179997

+
In-frameENST00000219299ENST00000535318CCDC113chr16

58301490

+CPNE2chr16

57179997

+
In-frameENST00000219299ENST00000537605CCDC113chr16

58301490

+CPNE2chr16

57179997

+
In-frameENST00000219299ENST00000565874CCDC113chr16

58301490

+CPNE2chr16

57179997

+
In-frameENST00000443128ENST00000290776CCDC113chr16

58301490

+CPNE2chr16

57179997

+
In-frameENST00000443128ENST00000535318CCDC113chr16

58301490

+CPNE2chr16

57179997

+
In-frameENST00000443128ENST00000537605CCDC113chr16

58301490

+CPNE2chr16

57179997

+
In-frameENST00000443128ENST00000565874CCDC113chr16

58301490

+CPNE2chr16

57179997

+
intron-3CDSENST00000566498ENST00000290776CCDC113chr16

58301490

+CPNE2chr16

57179997

+
intron-3CDSENST00000566498ENST00000535318CCDC113chr16

58301490

+CPNE2chr16

57179997

+
intron-3CDSENST00000566498ENST00000537605CCDC113chr16

58301490

+CPNE2chr16

57179997

+
intron-3CDSENST00000566498ENST00000565874CCDC113chr16

58301490

+CPNE2chr16

57179997

+
intron-3UTRENST00000566498ENST00000565951CCDC113chr16

58301490

+CPNE2chr16

57179997

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000219299CCDC113chr1658301490+ENST00000290776CPNE2chr1657179997+1623970791314411
ENST00000219299CCDC113chr1658301490+ENST00000537605CPNE2chr1657179997+1621970791314411
ENST00000219299CCDC113chr1658301490+ENST00000535318CPNE2chr1657179997+1623970791314411
ENST00000219299CCDC113chr1658301490+ENST00000565874CPNE2chr1657179997+1452970791314411
ENST00000443128CCDC113chr1658301490+ENST00000290776CPNE2chr1657179997+1461808791152357
ENST00000443128CCDC113chr1658301490+ENST00000537605CPNE2chr1657179997+1459808791152357
ENST00000443128CCDC113chr1658301490+ENST00000535318CPNE2chr1657179997+1461808791152357
ENST00000443128CCDC113chr1658301490+ENST00000565874CPNE2chr1657179997+1290808791152357

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000219299ENST00000290776CCDC113chr1658301490+CPNE2chr1657179997+0.0022341550.9977659
ENST00000219299ENST00000537605CCDC113chr1658301490+CPNE2chr1657179997+0.0022270920.9977729
ENST00000219299ENST00000535318CCDC113chr1658301490+CPNE2chr1657179997+0.0022341550.9977659
ENST00000219299ENST00000565874CCDC113chr1658301490+CPNE2chr1657179997+0.0024419320.997558
ENST00000443128ENST00000290776CCDC113chr1658301490+CPNE2chr1657179997+0.001991950.9980081
ENST00000443128ENST00000537605CCDC113chr1658301490+CPNE2chr1657179997+0.0020074080.99799263
ENST00000443128ENST00000535318CCDC113chr1658301490+CPNE2chr1657179997+0.001991950.9980081
ENST00000443128ENST00000565874CCDC113chr1658301490+CPNE2chr1657179997+0.0022691710.9977309

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Fusion Genomic Features for CCDC113-CPNE2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CCDC113chr1658301490+CPNE2chr1657179996+3.18E-070.99999964
CCDC113chr1658301490+CPNE2chr1657179996+3.18E-070.99999964

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CCDC113-CPNE2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:58301490/chr16:57179997)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CPNE2

Q96FN4

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Exhibits calcium-dependent cell membrane binding properties. {ECO:0000250|UniProtKB:P59108}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCCDC113chr16:58301490chr16:57179997ENST00000219299+7995_243297378.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC113chr16:58301490chr16:57179997ENST00000443128+6895_243243324.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCCDC113chr16:58301490chr16:57179997ENST00000219299+79280_354297378.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC113chr16:58301490chr16:57179997ENST00000443128+68280_354243324.0Coiled coilOntology_term=ECO:0000255
TgeneCPNE2chr16:58301490chr16:57179997ENST000002907761316138_263434549.0DomainC2 2
TgeneCPNE2chr16:58301490chr16:57179997ENST000002907761316305_507434549.0DomainVWFA
TgeneCPNE2chr16:58301490chr16:57179997ENST0000029077613165_131434549.0DomainC2 1
TgeneCPNE2chr16:58301490chr16:57179997ENST000005353181417138_263434549.0DomainC2 2
TgeneCPNE2chr16:58301490chr16:57179997ENST000005353181417305_507434549.0DomainVWFA
TgeneCPNE2chr16:58301490chr16:57179997ENST0000053531814175_131434549.0DomainC2 1
TgeneCPNE2chr16:58301490chr16:57179997ENST000005658741215138_263434549.0DomainC2 2
TgeneCPNE2chr16:58301490chr16:57179997ENST000005658741215305_507434549.0DomainVWFA
TgeneCPNE2chr16:58301490chr16:57179997ENST0000056587412155_131434549.0DomainC2 1
TgeneCPNE2chr16:58301490chr16:57179997ENST000002907761316247_304434549.0RegionLinker region
TgeneCPNE2chr16:58301490chr16:57179997ENST000005353181417247_304434549.0RegionLinker region
TgeneCPNE2chr16:58301490chr16:57179997ENST000005658741215247_304434549.0RegionLinker region


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Fusion Gene Sequence for CCDC113-CPNE2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>13579_13579_1_CCDC113-CPNE2_CCDC113_chr16_58301490_ENST00000219299_CPNE2_chr16_57179997_ENST00000290776_length(transcript)=1623nt_BP=970nt
GCAGCCGGAGTGACGCGTGGCCGCCGGCACCCGGAGCTCCTGGGCACACGGCATTGGCAGGGGCCGCTTCGGCAGAGTGATGACTGATGA
TGAGTCCGAGAGCGTCCTCTCCGACTCCCATGAAGGGTCGGAGCTGGAGCTGCCTGTTATCCAGCTGTGCGGGCTGGTGGAGGAGCTCAG
CTATGTAAACTCTGCTCTCAAAACTGAGACTGAGATGTTTGAGAAATATTACGCTAAACTGGAGCCCAGGGATCAGCGACCTCCACGATT
ATCAGAAATTAAAATATCAGCAGCAGATTATGCACAGTTTCGAGGCAGGCGTAGATCCAAATCCCGGACAGGTATGGACCGTGGGGTAGG
CCTGACTGCCGACCAAAAACTTGAGCTGGTACAAAAAGAGGTTGCGGACATGAAGGATGACTTACGACACACAAGGGCAAATGCGGAACG
CGACCTGCAGCATCACGAGGCGATCATTGAGGAGGCTGAAATTCGATGGAGTGAAGTTTCGAGAGAAGTGCATGAGTTTGAAAAAGATAT
TCTAAAAGCCATATCCAAGAAGAAAGGGAGTATTTTGGCCACTCAGAAAGTGATGAAATACATTGAGGACATGAACCGCCGGAGGGATAA
TATGAAGGAGAAATTACGTTTGAAAAATGTTTCTCTCAAAGTTCAGAGGAAAAAAATGCTTTTACAATTGAGGCAGAAGGAAGAGGTGAG
TGAGGCCCTTCACGATGTTGATTTTCAGCAGTTGAAGATAGAGAACGCTCAATTTCTTGAGACAATTGAAGCAAGGAATCAAGAACTGAC
CCAGCTAAAGCTGTCATCTGGAAACACTCTGCAGGTTCTCAATGCCTACAAAAGCAAGCTTCACAAGGCAATGGAAATATACCTCAATCT
GGACAAGGAGATCTTGCTGAGAAAAGAGCTACTTGAAAAAATTGAAAAAGAAACACTACAAGTAGAGGAGCAGTACTTCATCCTCCTCAT
CATCACGGACGGGGTCATCAGTGACATGGAGGAGACACGGCATGCCGTGGTGCAGGCTTCCAAGCTGCCCATGTCCATCATCATCGTGGG
CGTGGGCAATGCGGACTTCGCTGCCATGGAGTTCCTGGATGGGGACAGCCGCATGCTGCGCTCCCACACGGGGGAGGAGGCAGCCCGCGA
TATTGTGCAGTTCGTTCCCTTTCGAGAGTTCCGCAACGCAGCAAAAGAGACCTTGGCCAAAGCTGTGCTGGCGGAGCTGCCCCAACAAGT
TGTGCAGTATTTCAAGCATAAAAACCTGCCCCCCACCAACTCGGAGCCCGCCTGAGCTCCAGTGCCCAGCAGCAGCATGTCAGCTGAGCC
TCCTGCCCTCCCCCAGGAACATGCACGCTCACTCTGCTTCCTTGTGGGTGGCCTTTTTTTACCGATCCCCTTTTTTATTTTTTACAACCG
GACCTCCACCCCCAACTTCCTCCAGCCCAGCTGGGCTTCCTTTGTTGGAGTCAACTGTTGATGCTTCCAGGCCAAACTGGCTTCCTCTCC
TCCTCTCCCCACCTTTGCCATTCTTAAGTATTGAATGTACTTTGTATAATTTTAGTGGAATTGTTATTGAGAATAAAATTTTTACAATCA
TAA

>13579_13579_1_CCDC113-CPNE2_CCDC113_chr16_58301490_ENST00000219299_CPNE2_chr16_57179997_ENST00000290776_length(amino acids)=411AA_BP=297
MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQFRGRRRSKSRTGMD
RGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR
RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEI
YLNLDKEILLRKELLEKIEKETLQVEEQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRMLRSHTGEE
AARDIVQFVPFREFRNAAKETLAKAVLAELPQQVVQYFKHKNLPPTNSEPA

--------------------------------------------------------------
>13579_13579_2_CCDC113-CPNE2_CCDC113_chr16_58301490_ENST00000219299_CPNE2_chr16_57179997_ENST00000535318_length(transcript)=1623nt_BP=970nt
GCAGCCGGAGTGACGCGTGGCCGCCGGCACCCGGAGCTCCTGGGCACACGGCATTGGCAGGGGCCGCTTCGGCAGAGTGATGACTGATGA
TGAGTCCGAGAGCGTCCTCTCCGACTCCCATGAAGGGTCGGAGCTGGAGCTGCCTGTTATCCAGCTGTGCGGGCTGGTGGAGGAGCTCAG
CTATGTAAACTCTGCTCTCAAAACTGAGACTGAGATGTTTGAGAAATATTACGCTAAACTGGAGCCCAGGGATCAGCGACCTCCACGATT
ATCAGAAATTAAAATATCAGCAGCAGATTATGCACAGTTTCGAGGCAGGCGTAGATCCAAATCCCGGACAGGTATGGACCGTGGGGTAGG
CCTGACTGCCGACCAAAAACTTGAGCTGGTACAAAAAGAGGTTGCGGACATGAAGGATGACTTACGACACACAAGGGCAAATGCGGAACG
CGACCTGCAGCATCACGAGGCGATCATTGAGGAGGCTGAAATTCGATGGAGTGAAGTTTCGAGAGAAGTGCATGAGTTTGAAAAAGATAT
TCTAAAAGCCATATCCAAGAAGAAAGGGAGTATTTTGGCCACTCAGAAAGTGATGAAATACATTGAGGACATGAACCGCCGGAGGGATAA
TATGAAGGAGAAATTACGTTTGAAAAATGTTTCTCTCAAAGTTCAGAGGAAAAAAATGCTTTTACAATTGAGGCAGAAGGAAGAGGTGAG
TGAGGCCCTTCACGATGTTGATTTTCAGCAGTTGAAGATAGAGAACGCTCAATTTCTTGAGACAATTGAAGCAAGGAATCAAGAACTGAC
CCAGCTAAAGCTGTCATCTGGAAACACTCTGCAGGTTCTCAATGCCTACAAAAGCAAGCTTCACAAGGCAATGGAAATATACCTCAATCT
GGACAAGGAGATCTTGCTGAGAAAAGAGCTACTTGAAAAAATTGAAAAAGAAACACTACAAGTAGAGGAGCAGTACTTCATCCTCCTCAT
CATCACGGACGGGGTCATCAGTGACATGGAGGAGACACGGCATGCCGTGGTGCAGGCTTCCAAGCTGCCCATGTCCATCATCATCGTGGG
CGTGGGCAATGCGGACTTCGCTGCCATGGAGTTCCTGGATGGGGACAGCCGCATGCTGCGCTCCCACACGGGGGAGGAGGCAGCCCGCGA
TATTGTGCAGTTCGTTCCCTTTCGAGAGTTCCGCAACGCAGCAAAAGAGACCTTGGCCAAAGCTGTGCTGGCGGAGCTGCCCCAACAAGT
TGTGCAGTATTTCAAGCATAAAAACCTGCCCCCCACCAACTCGGAGCCCGCCTGAGCTCCAGTGCCCAGCAGCAGCATGTCAGCTGAGCC
TCCTGCCCTCCCCCAGGAACATGCACGCTCACTCTGCTTCCTTGTGGGTGGCCTTTTTTTACCGATCCCCTTTTTTATTTTTTACAACCG
GACCTCCACCCCCAACTTCCTCCAGCCCAGCTGGGCTTCCTTTGTTGGAGTCAACTGTTGATGCTTCCAGGCCAAACTGGCTTCCTCTCC
TCCTCTCCCCACCTTTGCCATTCTTAAGTATTGAATGTACTTTGTATAATTTTAGTGGAATTGTTATTGAGAATAAAATTTTTACAATCA
TAA

>13579_13579_2_CCDC113-CPNE2_CCDC113_chr16_58301490_ENST00000219299_CPNE2_chr16_57179997_ENST00000535318_length(amino acids)=411AA_BP=297
MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQFRGRRRSKSRTGMD
RGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR
RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEI
YLNLDKEILLRKELLEKIEKETLQVEEQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRMLRSHTGEE
AARDIVQFVPFREFRNAAKETLAKAVLAELPQQVVQYFKHKNLPPTNSEPA

--------------------------------------------------------------
>13579_13579_3_CCDC113-CPNE2_CCDC113_chr16_58301490_ENST00000219299_CPNE2_chr16_57179997_ENST00000537605_length(transcript)=1621nt_BP=970nt
GCAGCCGGAGTGACGCGTGGCCGCCGGCACCCGGAGCTCCTGGGCACACGGCATTGGCAGGGGCCGCTTCGGCAGAGTGATGACTGATGA
TGAGTCCGAGAGCGTCCTCTCCGACTCCCATGAAGGGTCGGAGCTGGAGCTGCCTGTTATCCAGCTGTGCGGGCTGGTGGAGGAGCTCAG
CTATGTAAACTCTGCTCTCAAAACTGAGACTGAGATGTTTGAGAAATATTACGCTAAACTGGAGCCCAGGGATCAGCGACCTCCACGATT
ATCAGAAATTAAAATATCAGCAGCAGATTATGCACAGTTTCGAGGCAGGCGTAGATCCAAATCCCGGACAGGTATGGACCGTGGGGTAGG
CCTGACTGCCGACCAAAAACTTGAGCTGGTACAAAAAGAGGTTGCGGACATGAAGGATGACTTACGACACACAAGGGCAAATGCGGAACG
CGACCTGCAGCATCACGAGGCGATCATTGAGGAGGCTGAAATTCGATGGAGTGAAGTTTCGAGAGAAGTGCATGAGTTTGAAAAAGATAT
TCTAAAAGCCATATCCAAGAAGAAAGGGAGTATTTTGGCCACTCAGAAAGTGATGAAATACATTGAGGACATGAACCGCCGGAGGGATAA
TATGAAGGAGAAATTACGTTTGAAAAATGTTTCTCTCAAAGTTCAGAGGAAAAAAATGCTTTTACAATTGAGGCAGAAGGAAGAGGTGAG
TGAGGCCCTTCACGATGTTGATTTTCAGCAGTTGAAGATAGAGAACGCTCAATTTCTTGAGACAATTGAAGCAAGGAATCAAGAACTGAC
CCAGCTAAAGCTGTCATCTGGAAACACTCTGCAGGTTCTCAATGCCTACAAAAGCAAGCTTCACAAGGCAATGGAAATATACCTCAATCT
GGACAAGGAGATCTTGCTGAGAAAAGAGCTACTTGAAAAAATTGAAAAAGAAACACTACAAGTAGAGGAGCAGTACTTCATCCTCCTCAT
CATCACGGACGGGGTCATCAGTGACATGGAGGAGACACGGCATGCCGTGGTGCAGGCTTCCAAGCTGCCCATGTCCATCATCATCGTGGG
CGTGGGCAATGCGGACTTCGCTGCCATGGAGTTCCTGGATGGGGACAGCCGCATGCTGCGCTCCCACACGGGGGAGGAGGCAGCCCGCGA
TATTGTGCAGTTCGTTCCCTTTCGAGAGTTCCGCAACGCAGCAAAAGAGACCTTGGCCAAAGCTGTGCTGGCGGAGCTGCCCCAACAAGT
TGTGCAGTATTTCAAGCATAAAAACCTGCCCCCCACCAACTCGGAGCCCGCCTGAGCTCCAGTGCCCAGCAGCAGCATGTCAGCTGAGCC
TCCTGCCCTCCCCCAGGAACATGCACGCTCACTCTGCTTCCTTGTGGGTGGCCTTTTTTTACCGATCCCCTTTTTTATTTTTTACAACCG
GACCTCCACCCCCAACTTCCTCCAGCCCAGCTGGGCTTCCTTTGTTGGAGTCAACTGTTGATGCTTCCAGGCCAAACTGGCTTCCTCTCC
TCCTCTCCCCACCTTTGCCATTCTTAAGTATTGAATGTACTTTGTATAATTTTAGTGGAATTGTTATTGAGAATAAAATTTTTACAATCA
T

>13579_13579_3_CCDC113-CPNE2_CCDC113_chr16_58301490_ENST00000219299_CPNE2_chr16_57179997_ENST00000537605_length(amino acids)=411AA_BP=297
MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQFRGRRRSKSRTGMD
RGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR
RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEI
YLNLDKEILLRKELLEKIEKETLQVEEQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRMLRSHTGEE
AARDIVQFVPFREFRNAAKETLAKAVLAELPQQVVQYFKHKNLPPTNSEPA

--------------------------------------------------------------
>13579_13579_4_CCDC113-CPNE2_CCDC113_chr16_58301490_ENST00000219299_CPNE2_chr16_57179997_ENST00000565874_length(transcript)=1452nt_BP=970nt
GCAGCCGGAGTGACGCGTGGCCGCCGGCACCCGGAGCTCCTGGGCACACGGCATTGGCAGGGGCCGCTTCGGCAGAGTGATGACTGATGA
TGAGTCCGAGAGCGTCCTCTCCGACTCCCATGAAGGGTCGGAGCTGGAGCTGCCTGTTATCCAGCTGTGCGGGCTGGTGGAGGAGCTCAG
CTATGTAAACTCTGCTCTCAAAACTGAGACTGAGATGTTTGAGAAATATTACGCTAAACTGGAGCCCAGGGATCAGCGACCTCCACGATT
ATCAGAAATTAAAATATCAGCAGCAGATTATGCACAGTTTCGAGGCAGGCGTAGATCCAAATCCCGGACAGGTATGGACCGTGGGGTAGG
CCTGACTGCCGACCAAAAACTTGAGCTGGTACAAAAAGAGGTTGCGGACATGAAGGATGACTTACGACACACAAGGGCAAATGCGGAACG
CGACCTGCAGCATCACGAGGCGATCATTGAGGAGGCTGAAATTCGATGGAGTGAAGTTTCGAGAGAAGTGCATGAGTTTGAAAAAGATAT
TCTAAAAGCCATATCCAAGAAGAAAGGGAGTATTTTGGCCACTCAGAAAGTGATGAAATACATTGAGGACATGAACCGCCGGAGGGATAA
TATGAAGGAGAAATTACGTTTGAAAAATGTTTCTCTCAAAGTTCAGAGGAAAAAAATGCTTTTACAATTGAGGCAGAAGGAAGAGGTGAG
TGAGGCCCTTCACGATGTTGATTTTCAGCAGTTGAAGATAGAGAACGCTCAATTTCTTGAGACAATTGAAGCAAGGAATCAAGAACTGAC
CCAGCTAAAGCTGTCATCTGGAAACACTCTGCAGGTTCTCAATGCCTACAAAAGCAAGCTTCACAAGGCAATGGAAATATACCTCAATCT
GGACAAGGAGATCTTGCTGAGAAAAGAGCTACTTGAAAAAATTGAAAAAGAAACACTACAAGTAGAGGAGCAGTACTTCATCCTCCTCAT
CATCACGGACGGGGTCATCAGTGACATGGAGGAGACACGGCATGCCGTGGTGCAGGCTTCCAAGCTGCCCATGTCCATCATCATCGTGGG
CGTGGGCAATGCGGACTTCGCTGCCATGGAGTTCCTGGATGGGGACAGCCGCATGCTGCGCTCCCACACGGGGGAGGAGGCAGCCCGCGA
TATTGTGCAGTTCGTTCCCTTTCGAGAGTTCCGCAACGCAGCAAAAGAGACCTTGGCCAAAGCTGTGCTGGCGGAGCTGCCCCAACAAGT
TGTGCAGTATTTCAAGCATAAAAACCTGCCCCCCACCAACTCGGAGCCCGCCTGAGCTCCAGTGCCCAGCAGCAGCATGTCAGCTGAGCC
TCCTGCCCTCCCCCAGGAACATGCACGCTCACTCTGCTTCCTTGTGGGTGGCCTTTTTTTACCGATCCCCTTTTTTATTTTTTACAACCG
GACCTCCACCCC

>13579_13579_4_CCDC113-CPNE2_CCDC113_chr16_58301490_ENST00000219299_CPNE2_chr16_57179997_ENST00000565874_length(amino acids)=411AA_BP=297
MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQFRGRRRSKSRTGMD
RGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR
RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEI
YLNLDKEILLRKELLEKIEKETLQVEEQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRMLRSHTGEE
AARDIVQFVPFREFRNAAKETLAKAVLAELPQQVVQYFKHKNLPPTNSEPA

--------------------------------------------------------------
>13579_13579_5_CCDC113-CPNE2_CCDC113_chr16_58301490_ENST00000443128_CPNE2_chr16_57179997_ENST00000290776_length(transcript)=1461nt_BP=808nt
GCAGCCGGAGTGACGCGTGGCCGCCGGCACCCGGAGCTCCTGGGCACACGGCATTGGCAGGGGCCGCTTCGGCAGAGTGATGACTGATGA
TGAGTCCGAGAGCGTCCTCTCCGACTCCCATGAAGGGTCGGAGCTGGAGCTGCCTGTTATCCAGCTGTGCGGGCTGGTGGAGGAGCTCAG
CTATGTAAACTCTGCTCTCAAAACTGAGACTGAGATGTTTGAGAAATATTACGCTAAACTGGAGCCCAGGGATCAGCGACCTCCACGATT
ATCAGAAATTAAAATATCAGCAGCAGATTATGCACAGGCGATCATTGAGGAGGCTGAAATTCGATGGAGTGAAGTTTCGAGAGAAGTGCA
TGAGTTTGAAAAAGATATTCTAAAAGCCATATCCAAGAAGAAAGGGAGTATTTTGGCCACTCAGAAAGTGATGAAATACATTGAGGACAT
GAACCGCCGGAGGGATAATATGAAGGAGAAATTACGTTTGAAAAATGTTTCTCTCAAAGTTCAGAGGAAAAAAATGCTTTTACAATTGAG
GCAGAAGGAAGAGGTGAGTGAGGCCCTTCACGATGTTGATTTTCAGCAGTTGAAGATAGAGAACGCTCAATTTCTTGAGACAATTGAAGC
AAGGAATCAAGAACTGACCCAGCTAAAGCTGTCATCTGGAAACACTCTGCAGGTTCTCAATGCCTACAAAAGCAAGCTTCACAAGGCAAT
GGAAATATACCTCAATCTGGACAAGGAGATCTTGCTGAGAAAAGAGCTACTTGAAAAAATTGAAAAAGAAACACTACAAGTAGAGGAGCA
GTACTTCATCCTCCTCATCATCACGGACGGGGTCATCAGTGACATGGAGGAGACACGGCATGCCGTGGTGCAGGCTTCCAAGCTGCCCAT
GTCCATCATCATCGTGGGCGTGGGCAATGCGGACTTCGCTGCCATGGAGTTCCTGGATGGGGACAGCCGCATGCTGCGCTCCCACACGGG
GGAGGAGGCAGCCCGCGATATTGTGCAGTTCGTTCCCTTTCGAGAGTTCCGCAACGCAGCAAAAGAGACCTTGGCCAAAGCTGTGCTGGC
GGAGCTGCCCCAACAAGTTGTGCAGTATTTCAAGCATAAAAACCTGCCCCCCACCAACTCGGAGCCCGCCTGAGCTCCAGTGCCCAGCAG
CAGCATGTCAGCTGAGCCTCCTGCCCTCCCCCAGGAACATGCACGCTCACTCTGCTTCCTTGTGGGTGGCCTTTTTTTACCGATCCCCTT
TTTTATTTTTTACAACCGGACCTCCACCCCCAACTTCCTCCAGCCCAGCTGGGCTTCCTTTGTTGGAGTCAACTGTTGATGCTTCCAGGC
CAAACTGGCTTCCTCTCCTCCTCTCCCCACCTTTGCCATTCTTAAGTATTGAATGTACTTTGTATAATTTTAGTGGAATTGTTATTGAGA
ATAAAATTTTTACAATCATAA

>13579_13579_5_CCDC113-CPNE2_CCDC113_chr16_58301490_ENST00000443128_CPNE2_chr16_57179997_ENST00000290776_length(amino acids)=357AA_BP=243
MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEVS
REVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLE
TIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEQYFILLIITDGVISDMEETRHAVVQAS
KLPMSIIIVGVGNADFAAMEFLDGDSRMLRSHTGEEAARDIVQFVPFREFRNAAKETLAKAVLAELPQQVVQYFKHKNLPPTNSEPA

--------------------------------------------------------------
>13579_13579_6_CCDC113-CPNE2_CCDC113_chr16_58301490_ENST00000443128_CPNE2_chr16_57179997_ENST00000535318_length(transcript)=1461nt_BP=808nt
GCAGCCGGAGTGACGCGTGGCCGCCGGCACCCGGAGCTCCTGGGCACACGGCATTGGCAGGGGCCGCTTCGGCAGAGTGATGACTGATGA
TGAGTCCGAGAGCGTCCTCTCCGACTCCCATGAAGGGTCGGAGCTGGAGCTGCCTGTTATCCAGCTGTGCGGGCTGGTGGAGGAGCTCAG
CTATGTAAACTCTGCTCTCAAAACTGAGACTGAGATGTTTGAGAAATATTACGCTAAACTGGAGCCCAGGGATCAGCGACCTCCACGATT
ATCAGAAATTAAAATATCAGCAGCAGATTATGCACAGGCGATCATTGAGGAGGCTGAAATTCGATGGAGTGAAGTTTCGAGAGAAGTGCA
TGAGTTTGAAAAAGATATTCTAAAAGCCATATCCAAGAAGAAAGGGAGTATTTTGGCCACTCAGAAAGTGATGAAATACATTGAGGACAT
GAACCGCCGGAGGGATAATATGAAGGAGAAATTACGTTTGAAAAATGTTTCTCTCAAAGTTCAGAGGAAAAAAATGCTTTTACAATTGAG
GCAGAAGGAAGAGGTGAGTGAGGCCCTTCACGATGTTGATTTTCAGCAGTTGAAGATAGAGAACGCTCAATTTCTTGAGACAATTGAAGC
AAGGAATCAAGAACTGACCCAGCTAAAGCTGTCATCTGGAAACACTCTGCAGGTTCTCAATGCCTACAAAAGCAAGCTTCACAAGGCAAT
GGAAATATACCTCAATCTGGACAAGGAGATCTTGCTGAGAAAAGAGCTACTTGAAAAAATTGAAAAAGAAACACTACAAGTAGAGGAGCA
GTACTTCATCCTCCTCATCATCACGGACGGGGTCATCAGTGACATGGAGGAGACACGGCATGCCGTGGTGCAGGCTTCCAAGCTGCCCAT
GTCCATCATCATCGTGGGCGTGGGCAATGCGGACTTCGCTGCCATGGAGTTCCTGGATGGGGACAGCCGCATGCTGCGCTCCCACACGGG
GGAGGAGGCAGCCCGCGATATTGTGCAGTTCGTTCCCTTTCGAGAGTTCCGCAACGCAGCAAAAGAGACCTTGGCCAAAGCTGTGCTGGC
GGAGCTGCCCCAACAAGTTGTGCAGTATTTCAAGCATAAAAACCTGCCCCCCACCAACTCGGAGCCCGCCTGAGCTCCAGTGCCCAGCAG
CAGCATGTCAGCTGAGCCTCCTGCCCTCCCCCAGGAACATGCACGCTCACTCTGCTTCCTTGTGGGTGGCCTTTTTTTACCGATCCCCTT
TTTTATTTTTTACAACCGGACCTCCACCCCCAACTTCCTCCAGCCCAGCTGGGCTTCCTTTGTTGGAGTCAACTGTTGATGCTTCCAGGC
CAAACTGGCTTCCTCTCCTCCTCTCCCCACCTTTGCCATTCTTAAGTATTGAATGTACTTTGTATAATTTTAGTGGAATTGTTATTGAGA
ATAAAATTTTTACAATCATAA

>13579_13579_6_CCDC113-CPNE2_CCDC113_chr16_58301490_ENST00000443128_CPNE2_chr16_57179997_ENST00000535318_length(amino acids)=357AA_BP=243
MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEVS
REVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLE
TIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEQYFILLIITDGVISDMEETRHAVVQAS
KLPMSIIIVGVGNADFAAMEFLDGDSRMLRSHTGEEAARDIVQFVPFREFRNAAKETLAKAVLAELPQQVVQYFKHKNLPPTNSEPA

--------------------------------------------------------------
>13579_13579_7_CCDC113-CPNE2_CCDC113_chr16_58301490_ENST00000443128_CPNE2_chr16_57179997_ENST00000537605_length(transcript)=1459nt_BP=808nt
GCAGCCGGAGTGACGCGTGGCCGCCGGCACCCGGAGCTCCTGGGCACACGGCATTGGCAGGGGCCGCTTCGGCAGAGTGATGACTGATGA
TGAGTCCGAGAGCGTCCTCTCCGACTCCCATGAAGGGTCGGAGCTGGAGCTGCCTGTTATCCAGCTGTGCGGGCTGGTGGAGGAGCTCAG
CTATGTAAACTCTGCTCTCAAAACTGAGACTGAGATGTTTGAGAAATATTACGCTAAACTGGAGCCCAGGGATCAGCGACCTCCACGATT
ATCAGAAATTAAAATATCAGCAGCAGATTATGCACAGGCGATCATTGAGGAGGCTGAAATTCGATGGAGTGAAGTTTCGAGAGAAGTGCA
TGAGTTTGAAAAAGATATTCTAAAAGCCATATCCAAGAAGAAAGGGAGTATTTTGGCCACTCAGAAAGTGATGAAATACATTGAGGACAT
GAACCGCCGGAGGGATAATATGAAGGAGAAATTACGTTTGAAAAATGTTTCTCTCAAAGTTCAGAGGAAAAAAATGCTTTTACAATTGAG
GCAGAAGGAAGAGGTGAGTGAGGCCCTTCACGATGTTGATTTTCAGCAGTTGAAGATAGAGAACGCTCAATTTCTTGAGACAATTGAAGC
AAGGAATCAAGAACTGACCCAGCTAAAGCTGTCATCTGGAAACACTCTGCAGGTTCTCAATGCCTACAAAAGCAAGCTTCACAAGGCAAT
GGAAATATACCTCAATCTGGACAAGGAGATCTTGCTGAGAAAAGAGCTACTTGAAAAAATTGAAAAAGAAACACTACAAGTAGAGGAGCA
GTACTTCATCCTCCTCATCATCACGGACGGGGTCATCAGTGACATGGAGGAGACACGGCATGCCGTGGTGCAGGCTTCCAAGCTGCCCAT
GTCCATCATCATCGTGGGCGTGGGCAATGCGGACTTCGCTGCCATGGAGTTCCTGGATGGGGACAGCCGCATGCTGCGCTCCCACACGGG
GGAGGAGGCAGCCCGCGATATTGTGCAGTTCGTTCCCTTTCGAGAGTTCCGCAACGCAGCAAAAGAGACCTTGGCCAAAGCTGTGCTGGC
GGAGCTGCCCCAACAAGTTGTGCAGTATTTCAAGCATAAAAACCTGCCCCCCACCAACTCGGAGCCCGCCTGAGCTCCAGTGCCCAGCAG
CAGCATGTCAGCTGAGCCTCCTGCCCTCCCCCAGGAACATGCACGCTCACTCTGCTTCCTTGTGGGTGGCCTTTTTTTACCGATCCCCTT
TTTTATTTTTTACAACCGGACCTCCACCCCCAACTTCCTCCAGCCCAGCTGGGCTTCCTTTGTTGGAGTCAACTGTTGATGCTTCCAGGC
CAAACTGGCTTCCTCTCCTCCTCTCCCCACCTTTGCCATTCTTAAGTATTGAATGTACTTTGTATAATTTTAGTGGAATTGTTATTGAGA
ATAAAATTTTTACAATCAT

>13579_13579_7_CCDC113-CPNE2_CCDC113_chr16_58301490_ENST00000443128_CPNE2_chr16_57179997_ENST00000537605_length(amino acids)=357AA_BP=243
MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEVS
REVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLE
TIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEQYFILLIITDGVISDMEETRHAVVQAS
KLPMSIIIVGVGNADFAAMEFLDGDSRMLRSHTGEEAARDIVQFVPFREFRNAAKETLAKAVLAELPQQVVQYFKHKNLPPTNSEPA

--------------------------------------------------------------
>13579_13579_8_CCDC113-CPNE2_CCDC113_chr16_58301490_ENST00000443128_CPNE2_chr16_57179997_ENST00000565874_length(transcript)=1290nt_BP=808nt
GCAGCCGGAGTGACGCGTGGCCGCCGGCACCCGGAGCTCCTGGGCACACGGCATTGGCAGGGGCCGCTTCGGCAGAGTGATGACTGATGA
TGAGTCCGAGAGCGTCCTCTCCGACTCCCATGAAGGGTCGGAGCTGGAGCTGCCTGTTATCCAGCTGTGCGGGCTGGTGGAGGAGCTCAG
CTATGTAAACTCTGCTCTCAAAACTGAGACTGAGATGTTTGAGAAATATTACGCTAAACTGGAGCCCAGGGATCAGCGACCTCCACGATT
ATCAGAAATTAAAATATCAGCAGCAGATTATGCACAGGCGATCATTGAGGAGGCTGAAATTCGATGGAGTGAAGTTTCGAGAGAAGTGCA
TGAGTTTGAAAAAGATATTCTAAAAGCCATATCCAAGAAGAAAGGGAGTATTTTGGCCACTCAGAAAGTGATGAAATACATTGAGGACAT
GAACCGCCGGAGGGATAATATGAAGGAGAAATTACGTTTGAAAAATGTTTCTCTCAAAGTTCAGAGGAAAAAAATGCTTTTACAATTGAG
GCAGAAGGAAGAGGTGAGTGAGGCCCTTCACGATGTTGATTTTCAGCAGTTGAAGATAGAGAACGCTCAATTTCTTGAGACAATTGAAGC
AAGGAATCAAGAACTGACCCAGCTAAAGCTGTCATCTGGAAACACTCTGCAGGTTCTCAATGCCTACAAAAGCAAGCTTCACAAGGCAAT
GGAAATATACCTCAATCTGGACAAGGAGATCTTGCTGAGAAAAGAGCTACTTGAAAAAATTGAAAAAGAAACACTACAAGTAGAGGAGCA
GTACTTCATCCTCCTCATCATCACGGACGGGGTCATCAGTGACATGGAGGAGACACGGCATGCCGTGGTGCAGGCTTCCAAGCTGCCCAT
GTCCATCATCATCGTGGGCGTGGGCAATGCGGACTTCGCTGCCATGGAGTTCCTGGATGGGGACAGCCGCATGCTGCGCTCCCACACGGG
GGAGGAGGCAGCCCGCGATATTGTGCAGTTCGTTCCCTTTCGAGAGTTCCGCAACGCAGCAAAAGAGACCTTGGCCAAAGCTGTGCTGGC
GGAGCTGCCCCAACAAGTTGTGCAGTATTTCAAGCATAAAAACCTGCCCCCCACCAACTCGGAGCCCGCCTGAGCTCCAGTGCCCAGCAG
CAGCATGTCAGCTGAGCCTCCTGCCCTCCCCCAGGAACATGCACGCTCACTCTGCTTCCTTGTGGGTGGCCTTTTTTTACCGATCCCCTT
TTTTATTTTTTACAACCGGACCTCCACCCC

>13579_13579_8_CCDC113-CPNE2_CCDC113_chr16_58301490_ENST00000443128_CPNE2_chr16_57179997_ENST00000565874_length(amino acids)=357AA_BP=243
MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQAIIEEAEIRWSEVS
REVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLE
TIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEQYFILLIITDGVISDMEETRHAVVQAS
KLPMSIIIVGVGNADFAAMEFLDGDSRMLRSHTGEEAARDIVQFVPFREFRNAAKETLAKAVLAELPQQVVQYFKHKNLPPTNSEPA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CCDC113-CPNE2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CCDC113-CPNE2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CCDC113-CPNE2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource