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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:HNRNPH3-RAB18 (FusionGDB2 ID:HG3189TG22931)

Fusion Gene Summary for HNRNPH3-RAB18

check button Fusion gene summary
Fusion gene informationFusion gene name: HNRNPH3-RAB18
Fusion gene ID: hg3189tg22931
HgeneTgene
Gene symbol

HNRNPH3

RAB18

Gene ID

3189

22931

Gene nameheterogeneous nuclear ribonucleoprotein H3RAB18, member RAS oncogene family
Synonyms2H9|HNRPH3RAB18LI1|WARBM3
Cytomap('HNRNPH3')('RAB18')

10q21.3

10p12.1

Type of geneprotein-codingprotein-coding
Descriptionheterogeneous nuclear ribonucleoprotein H3heterogeneous nuclear ribonucleoprotein 2H9hnRNP 2H9hnRNP H3ras-related protein Rab-18RAB18 small GTPase
Modification date2020031320200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000469172, ENST00000265866, 
ENST00000354695, ENST00000441000, 
Fusion gene scores* DoF score9 X 7 X 6=3788 X 7 X 4=224
# samples 109
** MAII scorelog2(10/378*10)=-1.91838623444635
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/224*10)=-1.31550182572793
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: HNRNPH3 [Title/Abstract] AND RAB18 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointHNRNPH3(70097090)-RAB18(27815757), # samples:1
Anticipated loss of major functional domain due to fusion event.HNRNPH3-RAB18 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
HNRNPH3-RAB18 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across HNRNPH3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across RAB18 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerTCGA-HU-A4GP-11AHNRNPH3chr10

70097090

+RAB18chr10

27815757

+


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Fusion Gene ORF analysis for HNRNPH3-RAB18

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000469172ENST00000356940HNRNPH3chr10

70097090

+RAB18chr10

27815757

+
3UTR-3CDSENST00000469172ENST00000535776HNRNPH3chr10

70097090

+RAB18chr10

27815757

+
3UTR-3UTRENST00000469172ENST00000465772HNRNPH3chr10

70097090

+RAB18chr10

27815757

+
3UTR-intronENST00000469172ENST00000375802HNRNPH3chr10

70097090

+RAB18chr10

27815757

+
5CDS-3UTRENST00000265866ENST00000465772HNRNPH3chr10

70097090

+RAB18chr10

27815757

+
5CDS-3UTRENST00000354695ENST00000465772HNRNPH3chr10

70097090

+RAB18chr10

27815757

+
5CDS-3UTRENST00000441000ENST00000465772HNRNPH3chr10

70097090

+RAB18chr10

27815757

+
5CDS-intronENST00000265866ENST00000375802HNRNPH3chr10

70097090

+RAB18chr10

27815757

+
5CDS-intronENST00000354695ENST00000375802HNRNPH3chr10

70097090

+RAB18chr10

27815757

+
5CDS-intronENST00000441000ENST00000375802HNRNPH3chr10

70097090

+RAB18chr10

27815757

+
In-frameENST00000265866ENST00000356940HNRNPH3chr10

70097090

+RAB18chr10

27815757

+
In-frameENST00000265866ENST00000535776HNRNPH3chr10

70097090

+RAB18chr10

27815757

+
In-frameENST00000354695ENST00000356940HNRNPH3chr10

70097090

+RAB18chr10

27815757

+
In-frameENST00000354695ENST00000535776HNRNPH3chr10

70097090

+RAB18chr10

27815757

+
In-frameENST00000441000ENST00000356940HNRNPH3chr10

70097090

+RAB18chr10

27815757

+
In-frameENST00000441000ENST00000535776HNRNPH3chr10

70097090

+RAB18chr10

27815757

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000265866HNRNPH3chr1070097090+ENST00000356940RAB18chr1027815757+4937277165773202
ENST00000265866HNRNPH3chr1070097090+ENST00000535776RAB18chr1027815757+1805277165581138
ENST00000441000HNRNPH3chr1070097090+ENST00000356940RAB18chr1027815757+4916256144752202
ENST00000441000HNRNPH3chr1070097090+ENST00000535776RAB18chr1027815757+1784256144560138
ENST00000354695HNRNPH3chr1070097090+ENST00000356940RAB18chr1027815757+4890230118726202
ENST00000354695HNRNPH3chr1070097090+ENST00000535776RAB18chr1027815757+1758230118534138

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000265866ENST00000356940HNRNPH3chr1070097090+RAB18chr1027815757+0.0021929150.9978071
ENST00000265866ENST00000535776HNRNPH3chr1070097090+RAB18chr1027815757+0.0037832350.9962167
ENST00000441000ENST00000356940HNRNPH3chr1070097090+RAB18chr1027815757+0.0021588380.9978411
ENST00000441000ENST00000535776HNRNPH3chr1070097090+RAB18chr1027815757+0.004308590.9956915
ENST00000354695ENST00000356940HNRNPH3chr1070097090+RAB18chr1027815757+0.0020506930.9979493
ENST00000354695ENST00000535776HNRNPH3chr1070097090+RAB18chr1027815757+0.0051762640.9948237

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Fusion Genomic Features for HNRNPH3-RAB18


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
HNRNPH3chr1070097090+RAB18chr1027815756+3.41E-050.9999659
HNRNPH3chr1070097090+RAB18chr1027815756+3.41E-050.9999659

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for HNRNPH3-RAB18


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:70097090/chr10:27815757)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRAB18chr10:70097090chr10:27815757ENST0000035694017122_12541207.0Nucleotide bindingNote=GTP
TgeneRAB18chr10:70097090chr10:27815757ENST0000035694017151_15341207.0Nucleotide bindingNote=GTP
TgeneRAB18chr10:70097090chr10:27815757ENST000003569401763_6741207.0Nucleotide bindingNote=GTP
TgeneRAB18chr10:70097090chr10:27815757ENST0000053577615122_12541143.0Nucleotide bindingNote=GTP
TgeneRAB18chr10:70097090chr10:27815757ENST0000053577615151_15341143.0Nucleotide bindingNote=GTP
TgeneRAB18chr10:70097090chr10:27815757ENST000005357761563_6741143.0Nucleotide bindingNote=GTP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneHNRNPH3chr10:70097090chr10:27815757ENST00000265866+210108_34437347.0Compositional biasNote=Gly-rich
HgeneHNRNPH3chr10:70097090chr10:27815757ENST00000354695+210108_34437332.0Compositional biasNote=Gly-rich
HgeneHNRNPH3chr10:70097090chr10:27815757ENST00000265866+21016_9337347.0DomainRRM 1
HgeneHNRNPH3chr10:70097090chr10:27815757ENST00000265866+210195_27037347.0DomainRRM 2
HgeneHNRNPH3chr10:70097090chr10:27815757ENST00000354695+21016_9337332.0DomainRRM 1
HgeneHNRNPH3chr10:70097090chr10:27815757ENST00000354695+210195_27037332.0DomainRRM 2
TgeneRAB18chr10:70097090chr10:27815757ENST000003569401737_4541207.0MotifEffector region
TgeneRAB18chr10:70097090chr10:27815757ENST000005357761537_4541143.0MotifEffector region
TgeneRAB18chr10:70097090chr10:27815757ENST000003569401715_2341207.0Nucleotide bindingNote=GTP
TgeneRAB18chr10:70097090chr10:27815757ENST000005357761515_2341143.0Nucleotide bindingNote=GTP


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Fusion Gene Sequence for HNRNPH3-RAB18


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>37216_37216_1_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000265866_RAB18_chr10_27815757_ENST00000356940_length(transcript)=4937nt_BP=277nt
TGCGCAGCTCCCTAAGCGGTTGTCACCGCTGGAGACGGTTGGGAGAACCGTTGTGGCGAGCGCTACACGAGGCAAACGACTTCTCCCTTC
TTTGAACTGGACCCCGCGAGCACCAGAGTCGGCGTAACTATCGCCTGACAGGCATTTAAATCAAACGGTATTGAGATGGATTGGGTTATG
AAACATAATGGTCCAAATGACGCTAGTGATGGGACAGTACGACTTCGTGGACTACCATTTGGTTGCAGCAAAGAGGAAATAGTTCAGTTC
TTTCAAGGTGTTGACTTTAAGGTGAAAACAATTTCAGTGGATGGAAATAAGGCTAAACTTGCAATATGGGATACTGCTGGTCAAGAGAGG
TTTAGAACATTAACTCCCAGCTATTATAGAGGTGCACAGGGTGTTATATTAGTTTATGATGTCACAAGAAGAGATACATTTGTTAAACTG
GATAATTGGTTAAATGAATTGGAAACATACTGTACAAGAAATGACATAGTAAACATGCTAGTTGGAAATAAAATCGATAAGGAAAATCGT
GAAGTCGATAGAAATGAAGGCCTGAAATTTGCACGAAAGCATTCCATGTTATTTATAGAGGCAAGTGCAAAAACCTGTGATGGTGTACAA
TGTGCCTTTGAAGAACTTGTTGAAAAGATCATTCAGACCCCTGGACTGTGGGAAAGTGAGAACCAGAATAAAGGAGTCAAACTGTCACAC
AGGGAAGAAGGCCAAGGAGGAGGAGCCTGTGGTGGTTATTGCTCTGTGTTATAAACTCTGGGAAATTCCATCTCTTGCATATTTGATCAG
ATAGTGACATCTTTCTGTATATAAACTCTTTAACTGCTATTTTAGGGACCTTGCAGTTTGCACATAATTGTTTTATATCATAGCAGTAAA
TATTTGCAAGAAATCCCACTCATCGACCCCGGGTAAAATGTTATGGTAAGCATGCACAGTTTGCAGTCTACAGTTTTTTTATGTAGCACA
AAATAGGTGTACCTTTATAAGTACATTCAATTTTATGATTTACATTTATCATGTAATTTTTAAAAAAATCCATCTATCTAGGATATGTTG
ATACAAAGTCTGCTTTTGCTATTCTTTTTGCTTAAATACTCCTATCATTTTCTGAATTACTTGGTATTTAGAACTCCTAGCACCACGGGG
AAGAATAGAGGTATCATCAAACGTGGCAAATTTTCTTTCAGGAATAATAAAGAGCATGATTCCACAGCTTTTCTGGGATGTTTGAGATTC
TTTTTTAGTACTAAGCAAAATTCTCATCACAGAATGTAGCCCAGGCCAATTTATAACTAAATCTCTATTTGTTCAGATGATGCTTCTAAA
ACAGCATTGATAGGTTAAAGAAGCTTGGTATTTTTAATTTACTTCAATGATTAGCTCAGTTGCTTAACTGGAGTTTTAATCCTGTGATAT
GTACATTGGATTCATGACTGTGCAGCATTTTTAGTTATGTGGTGTTTGGCAGAATGACAATAAGGTTTTCCCCCATTTTGGTTTCAGGAG
GACATGAATAGTGTGTTTATTGTAACTCCTCATACACTTTTAAAACCAACATCTTTTTTCATAAATGTTGGTAGTGTTTGTCCAGGTACC
TTAACTGTAGCTTGTGTAATGTTGATGAATATCTGTATCTTACGGCTTCCATAATGGCTAGTTGATATTCAAAAACCTATTTCTGTGTTT
TGAGGGGTGGGGAAAAAAAACACTAAGTGATAATTTGAAAAAGGCATATTGCTTCCAGATTCTGATGTGTGAGGGAAAATACTGTCACAA
TGAAAATCTTGACAATTTACTTAACAAGTAACCAGTAGTTCATCAAAACCAACTTGTACAGACTAATAAATCTTTTTCACAGTATTCAGT
TTTCTCACCTCTTGCTATTGTATATTGTAGATTTTTTTCATTCATGTGTTATTTAATTTACACTGATCTCTGCTATTTTAACCCCCCAAA
TAAGTTATTTGTCCTTTAAGGTTGGTTACTATAATACCCCTCAGTAAGATTCCAGTATTAATTTCTGGGCAGTTTGTTCTCTGTATACAA
TTGCAAATGATAAGCATTTTTGTGAGTGACCACCTTTGCAATATGTTTGTTAATTTACTTCATGTTGGGTTCTTTCTGAAATGTACATCT
TTACATATAAAAACCTCACATTCTACTTGATTTACACTTCCTAGTCTACATTACATGTGGTTGAAGGTTTTATACATTCTATATGCTTTT
ACTAAATATACAAGATTTACTACTAGAAATTTGGAGAAAGAACACTAACACATGTACTTGTGATTTGTTCATGTTATATTAAAACTTGAG
ATTTGTGTATTTATGTAGAGTCTGTATTGACAAGACTGTTGTTTTTTGCTCCTTGAGCTATATAATAATCTGTGTATTGGATTGTTGTCT
TGATTTGGTCTAAATTTGAATATATATGAGTTACTTGAATATAACAAAAATGAATTTTGTTTGATAGATTTATATTGTAACCTTTTTCTA
GTTCTTGAATAAATATAGCCTGCTTTCCCTAGATGCATTTGTGTAGGAAGTATATACATTTCCCTATTACTCTCATCAGCTGAAGAATAT
GTACTATTGTGTTACTCAAATTATGTGGCTTTCATTTTGTTGTTTTGTTGCAAGCTTAGTGTTTTGTAGTGGAGGTTTTGTAAATGAAAC
AGTTGTAATATCTAAGGTCAGGCACCTAGTAACAGGGTTTTGTTAATTCTTTTCAGAATCATTGAAGCAGTCTTAAAGGGTCTTTTGCAG
ATGGTACAAATTAGAACAATTAGAATATAGTATTTTGAGTTCTAGTAGTACTGAGATTGACCCAAACAAATAAAAAACTATTCAATTTCT
GAGTAATAGTTAATATTTATTGAAAGCTTCCTTGGTGCCAGATGCCTTTCTAAGTGCTGAATTATCTCATTAAACCTCACAGCAACCTTA
AGAGATTAGTACTCCTATTATGCCCATTTTAAAGGTGAGGACAACACAATGTAGGTATGTTAGGTAACCCCCAAAGATCACATAGCTACT
CAGTCACTGAGCTGGATTCCAGTCATGGCATTTTTACTTCTGAGCCCATACTCTTCACCATCGCTCATTTTACAATGGGTAGTTAGTTAC
CAGCTTTTTGTAACACAACCAAGTTAAGGCAGTTCCACTATTTCTTTATCACTCTTTTGTTATATGTAATAGAAGTATTTCACACTTTTG
GGTTATAGAGTAAATCCCATGATGTAAACCTACCTCATAAGTCATGTGACATAAAAGTTAAGGTAGTGGAGTAGGTGGTCTTATTTCTTT
CACCTGCTCAGAGTGGACTGAAAATCCTGACTTAGAAAAGGTACAAAGTTAGGGGACTTATGGTACCTTCACTTTTTATGTGAGAATAGA
AATTATGGAAACAGTAATTTGCTCAAAACTGAAATCTGGGGTGATGTTTTCATTTCATGTATTTGATTGCCATCCATAAACTCATACTTG
GTGTTGACATTCTAGCTGAGTGTTGTGGAAATAGACTTGATTTTGATTCATCGTAGCTTGCATGGTCAAGAGACATGATTCTCTACTAAG
GGTGGGGCTAGCACCATAGCTCATAAAAGAATCCTTCTTACACCAGTACTTGTTCTGCCTGTGAGTTGGCACAGACTTACCTAATAACCA
TAGTGTCTTTAAGTACAACTTAATACATATTTTTTCTGTGTATTTTTTTCAAATGAACTCAACAATTCTTCAGGTATTATAGATCAGAGA
TCCTCTCCATATTCAAGCATTATGCTTCTCTTTCTTGGGGGTACATTTCACTAGTAATACTTAGGAAGTTATTTTGTCTTTCCTGTATTT
CCCTAGTTAAGTATAGGGGTAAAAACGTTATTCAGCTTTCAGAAGACATTGTTCTGACTCCGACCCTGCCGTGTATACTCAACTATATAG
ACTTCACCCTGGGTTTTGCCTAAACTGTTGAAAGACGAGAATAAATAGACATAGACAGGCTAGCTAAGTCAAGACTAGGGGCTAAGGAAT
ATAGAATCACCCAGGTCTTTTTTTTTTTTTTTAATTTTTCTCTCCTCAGTTGGGAACATCTATCATGCTGGAGGACTACTGTGATGGGGC
TTTACATTTTACTGTTTTGTTGCTAGCTTATTGTTTCATACTTGGGAATCAGTCATGTTTCTGATTGTGGTATAAAGTTTGCTTAAGTGC
CCCTTAGTTAAAGCTGTTCAATGAATGTAAGCACACACACACCTACACACATATTTTGAATAGTCGTGTGTTCATGCCTGTTCTCAGTCT
TGTCCCCTTTACCGTTTCTCATGCAGGTTATTTCTTGCTTTTTTTTTTTTTCCTCTTTTTTAACCGGAGAAGCAACAAATTACGTAGTTT
TTTTTGTGTTTCTTTGATTACTAGTGAGCTTGAGTACTTTTAATATTTTATTGGATATGTTTGTGACTGACTTTAATTTCTTGTTTGTGT
GTGCTGTGGCTGCCCGATCCAGCACCTACTTCCTTCTCCCACCATACCACCCCCACCCCCACCCCTGCAAACAATTGGCATGTGGTTTGG
GTGGCATTGTCACACCCTCGGCTTTCTAGATTAACCCAGTTACCTTTTAGCAGTGCCCCACTTCCCCAGTAGCAATGGTTCAGGGGTAGG
CACCTGACCCAGACCAGACTACTGAGATAAAGATGTTTGCCTAGGCTTTTTCAGGAGCAATTGAAGACATCTTGTTGGAGATAGTGTGCT
GGGAGGAGTCACATTCTGAACTTGCTGCAGCTCGTTTTTCTAATATAAAGGAACCAGCCTGAGGCAGTACCAGGGTGAGAGGGAGTCTAT

>37216_37216_1_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000265866_RAB18_chr10_27815757_ENST00000356940_length(amino acids)=202AA_BP=37
MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGVDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRD
TFVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQNKG

--------------------------------------------------------------
>37216_37216_2_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000265866_RAB18_chr10_27815757_ENST00000535776_length(transcript)=1805nt_BP=277nt
TGCGCAGCTCCCTAAGCGGTTGTCACCGCTGGAGACGGTTGGGAGAACCGTTGTGGCGAGCGCTACACGAGGCAAACGACTTCTCCCTTC
TTTGAACTGGACCCCGCGAGCACCAGAGTCGGCGTAACTATCGCCTGACAGGCATTTAAATCAAACGGTATTGAGATGGATTGGGTTATG
AAACATAATGGTCCAAATGACGCTAGTGATGGGACAGTACGACTTCGTGGACTACCATTTGGTTGCAGCAAAGAGGAAATAGTTCAGTTC
TTTCAAGGTGTTGACTTTAAGGTGAAAACAATTTCAGTGGATGGAAATAAGGCTAAACTTGCAATATGGGAAAATCGTGAAGTCGATAGA
AATGAAGGCCTGAAATTTGCACGAAAGCATTCCATGTTATTTATAGAGGCAAGTGCAAAAACCTGTGATGGTGTACAATGTGCCTTTGAA
GAACTTGTTGAAAAGATCATTCAGACCCCTGGACTGTGGGAAAGTGAGAACCAGAATAAAGGAGTCAAACTGTCACACAGGGAAGAAGGC
CAAGGAGGAGGAGCCTGTGGTGGTTATTGCTCTGTGTTATAAACTCTGGGAAATTCCATCTCTTGCATATTTGATCAGATAGTGACATCT
TTCTGTATATAAACTCTTTAACTGCTATTTTAGGGACCTTGCAGTTTGCACATAATTGTTTTATATCATAGCAGTAAATATTTGCAAGAA
ATCCCACTCATCGACCCCGGGTAAAATGTTATGGTAAGCATGCACAGTTTGCAGTCTACAGTTTTTTTATGTAGCACAAAATAGGTGTAC
CTTTATAAGTACATTCAATTTTATGATTTACATTTATCATGTAATTTTTAAAAAAATCCATCTATCTAGGATATGTTGATACAAAGTCTG
CTTTTGCTATTCTTTTTGCTTAAATACTCCTATCATTTTCTGAATTACTTGGTATTTAGAACTCCTAGCACCACGGGGAAGAATAGAGGT
ATCATCAAACGTGGCAAATTTTCTTTCAGGAATAATAAAGAGCATGATTCCACAGCTTTTCTGGGATGTTTGAGATTCTTTTTTAGTACT
AAGCAAAATTCTCATCACAGAATGTAGCCCAGGCCAATTTATAACTAAATCTCTATTTGTTCAGATGATGCTTCTAAAACAGCATTGATA
GGTTAAAGAAGCTTGGTATTTTTAATTTACTTCAATGATTAGCTCAGTTGCTTAACTGGAGTTTTAATCCTGTGATATGTACATTGGATT
CATGACTGTGCAGCATTTTTAGTTATGTGGTGTTTGGCAGAATGACAATAAGGTTTTCCCCCATTTTGGTTTCAGGAGGACATGAATAGT
GTGTTTATTGTAACTCCTCATACACTTTTAAAACCAACATCTTTTTTCATAAATGTTGGTAGTGTTTGTCCAGGTACCTTAACTGTAGCT
TGTGTAATGTTGATGAATATCTGTATCTTACGGCTTCCATAATGGCTAGTTGATATTCAAAAACCTATTTCTGTGTTTTGAGGGGTGGGG
AAAAAAAACACTAAGTGATAATTTGAAAAAGGCATATTGCTTCCAGATTCTGATGTGTGAGGGAAAATACTGTCACAATGAAAATCTTGA
CAATTTACTTAACAAGTAACCAGTAGTTCATCAAAACCAACTTGTACAGACTAATAAATCTTTTTCACAGTATTCAGTTTTCTCACCTCT
TGCTATTGTATATTGTAGATTTTTTTCATTCATGTGTTATTTAATTTACACTGATCTCTGCTATTTTAACCCCCCAAATAAGTTATTTGT

>37216_37216_2_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000265866_RAB18_chr10_27815757_ENST00000535776_length(amino acids)=138AA_BP=37
MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGVDFKVKTISVDGNKAKLAIWENREVDRNEGLKFARKHSMLFIEASAKTCDGV

--------------------------------------------------------------
>37216_37216_3_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000354695_RAB18_chr10_27815757_ENST00000356940_length(transcript)=4890nt_BP=230nt
CCGTTGTGGCGAGCGCTACACGAGGCAAACGACTTCTCCCTTCTTTGAACTGGACCCCGCGAGCACCAGAGTCGGCGTAACTATCGCCTG
ACAGGCATTTAAATCAAACGGTATTGAGATGGATTGGGTTATGAAACATAATGGTCCAAATGACGCTAGTGATGGGACAGTACGACTTCG
TGGACTACCATTTGGTTGCAGCAAAGAGGAAATAGTTCAGTTCTTTCAAGGTGTTGACTTTAAGGTGAAAACAATTTCAGTGGATGGAAA
TAAGGCTAAACTTGCAATATGGGATACTGCTGGTCAAGAGAGGTTTAGAACATTAACTCCCAGCTATTATAGAGGTGCACAGGGTGTTAT
ATTAGTTTATGATGTCACAAGAAGAGATACATTTGTTAAACTGGATAATTGGTTAAATGAATTGGAAACATACTGTACAAGAAATGACAT
AGTAAACATGCTAGTTGGAAATAAAATCGATAAGGAAAATCGTGAAGTCGATAGAAATGAAGGCCTGAAATTTGCACGAAAGCATTCCAT
GTTATTTATAGAGGCAAGTGCAAAAACCTGTGATGGTGTACAATGTGCCTTTGAAGAACTTGTTGAAAAGATCATTCAGACCCCTGGACT
GTGGGAAAGTGAGAACCAGAATAAAGGAGTCAAACTGTCACACAGGGAAGAAGGCCAAGGAGGAGGAGCCTGTGGTGGTTATTGCTCTGT
GTTATAAACTCTGGGAAATTCCATCTCTTGCATATTTGATCAGATAGTGACATCTTTCTGTATATAAACTCTTTAACTGCTATTTTAGGG
ACCTTGCAGTTTGCACATAATTGTTTTATATCATAGCAGTAAATATTTGCAAGAAATCCCACTCATCGACCCCGGGTAAAATGTTATGGT
AAGCATGCACAGTTTGCAGTCTACAGTTTTTTTATGTAGCACAAAATAGGTGTACCTTTATAAGTACATTCAATTTTATGATTTACATTT
ATCATGTAATTTTTAAAAAAATCCATCTATCTAGGATATGTTGATACAAAGTCTGCTTTTGCTATTCTTTTTGCTTAAATACTCCTATCA
TTTTCTGAATTACTTGGTATTTAGAACTCCTAGCACCACGGGGAAGAATAGAGGTATCATCAAACGTGGCAAATTTTCTTTCAGGAATAA
TAAAGAGCATGATTCCACAGCTTTTCTGGGATGTTTGAGATTCTTTTTTAGTACTAAGCAAAATTCTCATCACAGAATGTAGCCCAGGCC
AATTTATAACTAAATCTCTATTTGTTCAGATGATGCTTCTAAAACAGCATTGATAGGTTAAAGAAGCTTGGTATTTTTAATTTACTTCAA
TGATTAGCTCAGTTGCTTAACTGGAGTTTTAATCCTGTGATATGTACATTGGATTCATGACTGTGCAGCATTTTTAGTTATGTGGTGTTT
GGCAGAATGACAATAAGGTTTTCCCCCATTTTGGTTTCAGGAGGACATGAATAGTGTGTTTATTGTAACTCCTCATACACTTTTAAAACC
AACATCTTTTTTCATAAATGTTGGTAGTGTTTGTCCAGGTACCTTAACTGTAGCTTGTGTAATGTTGATGAATATCTGTATCTTACGGCT
TCCATAATGGCTAGTTGATATTCAAAAACCTATTTCTGTGTTTTGAGGGGTGGGGAAAAAAAACACTAAGTGATAATTTGAAAAAGGCAT
ATTGCTTCCAGATTCTGATGTGTGAGGGAAAATACTGTCACAATGAAAATCTTGACAATTTACTTAACAAGTAACCAGTAGTTCATCAAA
ACCAACTTGTACAGACTAATAAATCTTTTTCACAGTATTCAGTTTTCTCACCTCTTGCTATTGTATATTGTAGATTTTTTTCATTCATGT
GTTATTTAATTTACACTGATCTCTGCTATTTTAACCCCCCAAATAAGTTATTTGTCCTTTAAGGTTGGTTACTATAATACCCCTCAGTAA
GATTCCAGTATTAATTTCTGGGCAGTTTGTTCTCTGTATACAATTGCAAATGATAAGCATTTTTGTGAGTGACCACCTTTGCAATATGTT
TGTTAATTTACTTCATGTTGGGTTCTTTCTGAAATGTACATCTTTACATATAAAAACCTCACATTCTACTTGATTTACACTTCCTAGTCT
ACATTACATGTGGTTGAAGGTTTTATACATTCTATATGCTTTTACTAAATATACAAGATTTACTACTAGAAATTTGGAGAAAGAACACTA
ACACATGTACTTGTGATTTGTTCATGTTATATTAAAACTTGAGATTTGTGTATTTATGTAGAGTCTGTATTGACAAGACTGTTGTTTTTT
GCTCCTTGAGCTATATAATAATCTGTGTATTGGATTGTTGTCTTGATTTGGTCTAAATTTGAATATATATGAGTTACTTGAATATAACAA
AAATGAATTTTGTTTGATAGATTTATATTGTAACCTTTTTCTAGTTCTTGAATAAATATAGCCTGCTTTCCCTAGATGCATTTGTGTAGG
AAGTATATACATTTCCCTATTACTCTCATCAGCTGAAGAATATGTACTATTGTGTTACTCAAATTATGTGGCTTTCATTTTGTTGTTTTG
TTGCAAGCTTAGTGTTTTGTAGTGGAGGTTTTGTAAATGAAACAGTTGTAATATCTAAGGTCAGGCACCTAGTAACAGGGTTTTGTTAAT
TCTTTTCAGAATCATTGAAGCAGTCTTAAAGGGTCTTTTGCAGATGGTACAAATTAGAACAATTAGAATATAGTATTTTGAGTTCTAGTA
GTACTGAGATTGACCCAAACAAATAAAAAACTATTCAATTTCTGAGTAATAGTTAATATTTATTGAAAGCTTCCTTGGTGCCAGATGCCT
TTCTAAGTGCTGAATTATCTCATTAAACCTCACAGCAACCTTAAGAGATTAGTACTCCTATTATGCCCATTTTAAAGGTGAGGACAACAC
AATGTAGGTATGTTAGGTAACCCCCAAAGATCACATAGCTACTCAGTCACTGAGCTGGATTCCAGTCATGGCATTTTTACTTCTGAGCCC
ATACTCTTCACCATCGCTCATTTTACAATGGGTAGTTAGTTACCAGCTTTTTGTAACACAACCAAGTTAAGGCAGTTCCACTATTTCTTT
ATCACTCTTTTGTTATATGTAATAGAAGTATTTCACACTTTTGGGTTATAGAGTAAATCCCATGATGTAAACCTACCTCATAAGTCATGT
GACATAAAAGTTAAGGTAGTGGAGTAGGTGGTCTTATTTCTTTCACCTGCTCAGAGTGGACTGAAAATCCTGACTTAGAAAAGGTACAAA
GTTAGGGGACTTATGGTACCTTCACTTTTTATGTGAGAATAGAAATTATGGAAACAGTAATTTGCTCAAAACTGAAATCTGGGGTGATGT
TTTCATTTCATGTATTTGATTGCCATCCATAAACTCATACTTGGTGTTGACATTCTAGCTGAGTGTTGTGGAAATAGACTTGATTTTGAT
TCATCGTAGCTTGCATGGTCAAGAGACATGATTCTCTACTAAGGGTGGGGCTAGCACCATAGCTCATAAAAGAATCCTTCTTACACCAGT
ACTTGTTCTGCCTGTGAGTTGGCACAGACTTACCTAATAACCATAGTGTCTTTAAGTACAACTTAATACATATTTTTTCTGTGTATTTTT
TTCAAATGAACTCAACAATTCTTCAGGTATTATAGATCAGAGATCCTCTCCATATTCAAGCATTATGCTTCTCTTTCTTGGGGGTACATT
TCACTAGTAATACTTAGGAAGTTATTTTGTCTTTCCTGTATTTCCCTAGTTAAGTATAGGGGTAAAAACGTTATTCAGCTTTCAGAAGAC
ATTGTTCTGACTCCGACCCTGCCGTGTATACTCAACTATATAGACTTCACCCTGGGTTTTGCCTAAACTGTTGAAAGACGAGAATAAATA
GACATAGACAGGCTAGCTAAGTCAAGACTAGGGGCTAAGGAATATAGAATCACCCAGGTCTTTTTTTTTTTTTTTAATTTTTCTCTCCTC
AGTTGGGAACATCTATCATGCTGGAGGACTACTGTGATGGGGCTTTACATTTTACTGTTTTGTTGCTAGCTTATTGTTTCATACTTGGGA
ATCAGTCATGTTTCTGATTGTGGTATAAAGTTTGCTTAAGTGCCCCTTAGTTAAAGCTGTTCAATGAATGTAAGCACACACACACCTACA
CACATATTTTGAATAGTCGTGTGTTCATGCCTGTTCTCAGTCTTGTCCCCTTTACCGTTTCTCATGCAGGTTATTTCTTGCTTTTTTTTT
TTTTCCTCTTTTTTAACCGGAGAAGCAACAAATTACGTAGTTTTTTTTGTGTTTCTTTGATTACTAGTGAGCTTGAGTACTTTTAATATT
TTATTGGATATGTTTGTGACTGACTTTAATTTCTTGTTTGTGTGTGCTGTGGCTGCCCGATCCAGCACCTACTTCCTTCTCCCACCATAC
CACCCCCACCCCCACCCCTGCAAACAATTGGCATGTGGTTTGGGTGGCATTGTCACACCCTCGGCTTTCTAGATTAACCCAGTTACCTTT
TAGCAGTGCCCCACTTCCCCAGTAGCAATGGTTCAGGGGTAGGCACCTGACCCAGACCAGACTACTGAGATAAAGATGTTTGCCTAGGCT
TTTTCAGGAGCAATTGAAGACATCTTGTTGGAGATAGTGTGCTGGGAGGAGTCACATTCTGAACTTGCTGCAGCTCGTTTTTCTAATATA
AAGGAACCAGCCTGAGGCAGTACCAGGGTGAGAGGGAGTCTATTGGAGCCCTTGGGAACTTCTGGATCAAATTGGACCTGAATTGAGATC

>37216_37216_3_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000354695_RAB18_chr10_27815757_ENST00000356940_length(amino acids)=202AA_BP=37
MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGVDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRD
TFVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQNKG

--------------------------------------------------------------
>37216_37216_4_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000354695_RAB18_chr10_27815757_ENST00000535776_length(transcript)=1758nt_BP=230nt
CCGTTGTGGCGAGCGCTACACGAGGCAAACGACTTCTCCCTTCTTTGAACTGGACCCCGCGAGCACCAGAGTCGGCGTAACTATCGCCTG
ACAGGCATTTAAATCAAACGGTATTGAGATGGATTGGGTTATGAAACATAATGGTCCAAATGACGCTAGTGATGGGACAGTACGACTTCG
TGGACTACCATTTGGTTGCAGCAAAGAGGAAATAGTTCAGTTCTTTCAAGGTGTTGACTTTAAGGTGAAAACAATTTCAGTGGATGGAAA
TAAGGCTAAACTTGCAATATGGGAAAATCGTGAAGTCGATAGAAATGAAGGCCTGAAATTTGCACGAAAGCATTCCATGTTATTTATAGA
GGCAAGTGCAAAAACCTGTGATGGTGTACAATGTGCCTTTGAAGAACTTGTTGAAAAGATCATTCAGACCCCTGGACTGTGGGAAAGTGA
GAACCAGAATAAAGGAGTCAAACTGTCACACAGGGAAGAAGGCCAAGGAGGAGGAGCCTGTGGTGGTTATTGCTCTGTGTTATAAACTCT
GGGAAATTCCATCTCTTGCATATTTGATCAGATAGTGACATCTTTCTGTATATAAACTCTTTAACTGCTATTTTAGGGACCTTGCAGTTT
GCACATAATTGTTTTATATCATAGCAGTAAATATTTGCAAGAAATCCCACTCATCGACCCCGGGTAAAATGTTATGGTAAGCATGCACAG
TTTGCAGTCTACAGTTTTTTTATGTAGCACAAAATAGGTGTACCTTTATAAGTACATTCAATTTTATGATTTACATTTATCATGTAATTT
TTAAAAAAATCCATCTATCTAGGATATGTTGATACAAAGTCTGCTTTTGCTATTCTTTTTGCTTAAATACTCCTATCATTTTCTGAATTA
CTTGGTATTTAGAACTCCTAGCACCACGGGGAAGAATAGAGGTATCATCAAACGTGGCAAATTTTCTTTCAGGAATAATAAAGAGCATGA
TTCCACAGCTTTTCTGGGATGTTTGAGATTCTTTTTTAGTACTAAGCAAAATTCTCATCACAGAATGTAGCCCAGGCCAATTTATAACTA
AATCTCTATTTGTTCAGATGATGCTTCTAAAACAGCATTGATAGGTTAAAGAAGCTTGGTATTTTTAATTTACTTCAATGATTAGCTCAG
TTGCTTAACTGGAGTTTTAATCCTGTGATATGTACATTGGATTCATGACTGTGCAGCATTTTTAGTTATGTGGTGTTTGGCAGAATGACA
ATAAGGTTTTCCCCCATTTTGGTTTCAGGAGGACATGAATAGTGTGTTTATTGTAACTCCTCATACACTTTTAAAACCAACATCTTTTTT
CATAAATGTTGGTAGTGTTTGTCCAGGTACCTTAACTGTAGCTTGTGTAATGTTGATGAATATCTGTATCTTACGGCTTCCATAATGGCT
AGTTGATATTCAAAAACCTATTTCTGTGTTTTGAGGGGTGGGGAAAAAAAACACTAAGTGATAATTTGAAAAAGGCATATTGCTTCCAGA
TTCTGATGTGTGAGGGAAAATACTGTCACAATGAAAATCTTGACAATTTACTTAACAAGTAACCAGTAGTTCATCAAAACCAACTTGTAC
AGACTAATAAATCTTTTTCACAGTATTCAGTTTTCTCACCTCTTGCTATTGTATATTGTAGATTTTTTTCATTCATGTGTTATTTAATTT

>37216_37216_4_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000354695_RAB18_chr10_27815757_ENST00000535776_length(amino acids)=138AA_BP=37
MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGVDFKVKTISVDGNKAKLAIWENREVDRNEGLKFARKHSMLFIEASAKTCDGV

--------------------------------------------------------------
>37216_37216_5_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000441000_RAB18_chr10_27815757_ENST00000356940_length(transcript)=4916nt_BP=256nt
GTCACCGCTGGAGACGGTTGGGAGAACCGTTGTGGCGAGCGCTACACGAGGCAAACGACTTCTCCCTTCTTTGAACTGGACCCCGCGAGC
ACCAGAGTCGGCGTAACTATCGCCTGACAGGCATTTAAATCAAACGGTATTGAGATGGATTGGGTTATGAAACATAATGGTCCAAATGAC
GCTAGTGATGGGACAGTACGACTTCGTGGACTACCATTTGGTTGCAGCAAAGAGGAAATAGTTCAGTTCTTTCAAGGTGTTGACTTTAAG
GTGAAAACAATTTCAGTGGATGGAAATAAGGCTAAACTTGCAATATGGGATACTGCTGGTCAAGAGAGGTTTAGAACATTAACTCCCAGC
TATTATAGAGGTGCACAGGGTGTTATATTAGTTTATGATGTCACAAGAAGAGATACATTTGTTAAACTGGATAATTGGTTAAATGAATTG
GAAACATACTGTACAAGAAATGACATAGTAAACATGCTAGTTGGAAATAAAATCGATAAGGAAAATCGTGAAGTCGATAGAAATGAAGGC
CTGAAATTTGCACGAAAGCATTCCATGTTATTTATAGAGGCAAGTGCAAAAACCTGTGATGGTGTACAATGTGCCTTTGAAGAACTTGTT
GAAAAGATCATTCAGACCCCTGGACTGTGGGAAAGTGAGAACCAGAATAAAGGAGTCAAACTGTCACACAGGGAAGAAGGCCAAGGAGGA
GGAGCCTGTGGTGGTTATTGCTCTGTGTTATAAACTCTGGGAAATTCCATCTCTTGCATATTTGATCAGATAGTGACATCTTTCTGTATA
TAAACTCTTTAACTGCTATTTTAGGGACCTTGCAGTTTGCACATAATTGTTTTATATCATAGCAGTAAATATTTGCAAGAAATCCCACTC
ATCGACCCCGGGTAAAATGTTATGGTAAGCATGCACAGTTTGCAGTCTACAGTTTTTTTATGTAGCACAAAATAGGTGTACCTTTATAAG
TACATTCAATTTTATGATTTACATTTATCATGTAATTTTTAAAAAAATCCATCTATCTAGGATATGTTGATACAAAGTCTGCTTTTGCTA
TTCTTTTTGCTTAAATACTCCTATCATTTTCTGAATTACTTGGTATTTAGAACTCCTAGCACCACGGGGAAGAATAGAGGTATCATCAAA
CGTGGCAAATTTTCTTTCAGGAATAATAAAGAGCATGATTCCACAGCTTTTCTGGGATGTTTGAGATTCTTTTTTAGTACTAAGCAAAAT
TCTCATCACAGAATGTAGCCCAGGCCAATTTATAACTAAATCTCTATTTGTTCAGATGATGCTTCTAAAACAGCATTGATAGGTTAAAGA
AGCTTGGTATTTTTAATTTACTTCAATGATTAGCTCAGTTGCTTAACTGGAGTTTTAATCCTGTGATATGTACATTGGATTCATGACTGT
GCAGCATTTTTAGTTATGTGGTGTTTGGCAGAATGACAATAAGGTTTTCCCCCATTTTGGTTTCAGGAGGACATGAATAGTGTGTTTATT
GTAACTCCTCATACACTTTTAAAACCAACATCTTTTTTCATAAATGTTGGTAGTGTTTGTCCAGGTACCTTAACTGTAGCTTGTGTAATG
TTGATGAATATCTGTATCTTACGGCTTCCATAATGGCTAGTTGATATTCAAAAACCTATTTCTGTGTTTTGAGGGGTGGGGAAAAAAAAC
ACTAAGTGATAATTTGAAAAAGGCATATTGCTTCCAGATTCTGATGTGTGAGGGAAAATACTGTCACAATGAAAATCTTGACAATTTACT
TAACAAGTAACCAGTAGTTCATCAAAACCAACTTGTACAGACTAATAAATCTTTTTCACAGTATTCAGTTTTCTCACCTCTTGCTATTGT
ATATTGTAGATTTTTTTCATTCATGTGTTATTTAATTTACACTGATCTCTGCTATTTTAACCCCCCAAATAAGTTATTTGTCCTTTAAGG
TTGGTTACTATAATACCCCTCAGTAAGATTCCAGTATTAATTTCTGGGCAGTTTGTTCTCTGTATACAATTGCAAATGATAAGCATTTTT
GTGAGTGACCACCTTTGCAATATGTTTGTTAATTTACTTCATGTTGGGTTCTTTCTGAAATGTACATCTTTACATATAAAAACCTCACAT
TCTACTTGATTTACACTTCCTAGTCTACATTACATGTGGTTGAAGGTTTTATACATTCTATATGCTTTTACTAAATATACAAGATTTACT
ACTAGAAATTTGGAGAAAGAACACTAACACATGTACTTGTGATTTGTTCATGTTATATTAAAACTTGAGATTTGTGTATTTATGTAGAGT
CTGTATTGACAAGACTGTTGTTTTTTGCTCCTTGAGCTATATAATAATCTGTGTATTGGATTGTTGTCTTGATTTGGTCTAAATTTGAAT
ATATATGAGTTACTTGAATATAACAAAAATGAATTTTGTTTGATAGATTTATATTGTAACCTTTTTCTAGTTCTTGAATAAATATAGCCT
GCTTTCCCTAGATGCATTTGTGTAGGAAGTATATACATTTCCCTATTACTCTCATCAGCTGAAGAATATGTACTATTGTGTTACTCAAAT
TATGTGGCTTTCATTTTGTTGTTTTGTTGCAAGCTTAGTGTTTTGTAGTGGAGGTTTTGTAAATGAAACAGTTGTAATATCTAAGGTCAG
GCACCTAGTAACAGGGTTTTGTTAATTCTTTTCAGAATCATTGAAGCAGTCTTAAAGGGTCTTTTGCAGATGGTACAAATTAGAACAATT
AGAATATAGTATTTTGAGTTCTAGTAGTACTGAGATTGACCCAAACAAATAAAAAACTATTCAATTTCTGAGTAATAGTTAATATTTATT
GAAAGCTTCCTTGGTGCCAGATGCCTTTCTAAGTGCTGAATTATCTCATTAAACCTCACAGCAACCTTAAGAGATTAGTACTCCTATTAT
GCCCATTTTAAAGGTGAGGACAACACAATGTAGGTATGTTAGGTAACCCCCAAAGATCACATAGCTACTCAGTCACTGAGCTGGATTCCA
GTCATGGCATTTTTACTTCTGAGCCCATACTCTTCACCATCGCTCATTTTACAATGGGTAGTTAGTTACCAGCTTTTTGTAACACAACCA
AGTTAAGGCAGTTCCACTATTTCTTTATCACTCTTTTGTTATATGTAATAGAAGTATTTCACACTTTTGGGTTATAGAGTAAATCCCATG
ATGTAAACCTACCTCATAAGTCATGTGACATAAAAGTTAAGGTAGTGGAGTAGGTGGTCTTATTTCTTTCACCTGCTCAGAGTGGACTGA
AAATCCTGACTTAGAAAAGGTACAAAGTTAGGGGACTTATGGTACCTTCACTTTTTATGTGAGAATAGAAATTATGGAAACAGTAATTTG
CTCAAAACTGAAATCTGGGGTGATGTTTTCATTTCATGTATTTGATTGCCATCCATAAACTCATACTTGGTGTTGACATTCTAGCTGAGT
GTTGTGGAAATAGACTTGATTTTGATTCATCGTAGCTTGCATGGTCAAGAGACATGATTCTCTACTAAGGGTGGGGCTAGCACCATAGCT
CATAAAAGAATCCTTCTTACACCAGTACTTGTTCTGCCTGTGAGTTGGCACAGACTTACCTAATAACCATAGTGTCTTTAAGTACAACTT
AATACATATTTTTTCTGTGTATTTTTTTCAAATGAACTCAACAATTCTTCAGGTATTATAGATCAGAGATCCTCTCCATATTCAAGCATT
ATGCTTCTCTTTCTTGGGGGTACATTTCACTAGTAATACTTAGGAAGTTATTTTGTCTTTCCTGTATTTCCCTAGTTAAGTATAGGGGTA
AAAACGTTATTCAGCTTTCAGAAGACATTGTTCTGACTCCGACCCTGCCGTGTATACTCAACTATATAGACTTCACCCTGGGTTTTGCCT
AAACTGTTGAAAGACGAGAATAAATAGACATAGACAGGCTAGCTAAGTCAAGACTAGGGGCTAAGGAATATAGAATCACCCAGGTCTTTT
TTTTTTTTTTTAATTTTTCTCTCCTCAGTTGGGAACATCTATCATGCTGGAGGACTACTGTGATGGGGCTTTACATTTTACTGTTTTGTT
GCTAGCTTATTGTTTCATACTTGGGAATCAGTCATGTTTCTGATTGTGGTATAAAGTTTGCTTAAGTGCCCCTTAGTTAAAGCTGTTCAA
TGAATGTAAGCACACACACACCTACACACATATTTTGAATAGTCGTGTGTTCATGCCTGTTCTCAGTCTTGTCCCCTTTACCGTTTCTCA
TGCAGGTTATTTCTTGCTTTTTTTTTTTTTCCTCTTTTTTAACCGGAGAAGCAACAAATTACGTAGTTTTTTTTGTGTTTCTTTGATTAC
TAGTGAGCTTGAGTACTTTTAATATTTTATTGGATATGTTTGTGACTGACTTTAATTTCTTGTTTGTGTGTGCTGTGGCTGCCCGATCCA
GCACCTACTTCCTTCTCCCACCATACCACCCCCACCCCCACCCCTGCAAACAATTGGCATGTGGTTTGGGTGGCATTGTCACACCCTCGG
CTTTCTAGATTAACCCAGTTACCTTTTAGCAGTGCCCCACTTCCCCAGTAGCAATGGTTCAGGGGTAGGCACCTGACCCAGACCAGACTA
CTGAGATAAAGATGTTTGCCTAGGCTTTTTCAGGAGCAATTGAAGACATCTTGTTGGAGATAGTGTGCTGGGAGGAGTCACATTCTGAAC
TTGCTGCAGCTCGTTTTTCTAATATAAAGGAACCAGCCTGAGGCAGTACCAGGGTGAGAGGGAGTCTATTGGAGCCCTTGGGAACTTCTG

>37216_37216_5_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000441000_RAB18_chr10_27815757_ENST00000356940_length(amino acids)=202AA_BP=37
MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGVDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRD
TFVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQNKG

--------------------------------------------------------------
>37216_37216_6_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000441000_RAB18_chr10_27815757_ENST00000535776_length(transcript)=1784nt_BP=256nt
GTCACCGCTGGAGACGGTTGGGAGAACCGTTGTGGCGAGCGCTACACGAGGCAAACGACTTCTCCCTTCTTTGAACTGGACCCCGCGAGC
ACCAGAGTCGGCGTAACTATCGCCTGACAGGCATTTAAATCAAACGGTATTGAGATGGATTGGGTTATGAAACATAATGGTCCAAATGAC
GCTAGTGATGGGACAGTACGACTTCGTGGACTACCATTTGGTTGCAGCAAAGAGGAAATAGTTCAGTTCTTTCAAGGTGTTGACTTTAAG
GTGAAAACAATTTCAGTGGATGGAAATAAGGCTAAACTTGCAATATGGGAAAATCGTGAAGTCGATAGAAATGAAGGCCTGAAATTTGCA
CGAAAGCATTCCATGTTATTTATAGAGGCAAGTGCAAAAACCTGTGATGGTGTACAATGTGCCTTTGAAGAACTTGTTGAAAAGATCATT
CAGACCCCTGGACTGTGGGAAAGTGAGAACCAGAATAAAGGAGTCAAACTGTCACACAGGGAAGAAGGCCAAGGAGGAGGAGCCTGTGGT
GGTTATTGCTCTGTGTTATAAACTCTGGGAAATTCCATCTCTTGCATATTTGATCAGATAGTGACATCTTTCTGTATATAAACTCTTTAA
CTGCTATTTTAGGGACCTTGCAGTTTGCACATAATTGTTTTATATCATAGCAGTAAATATTTGCAAGAAATCCCACTCATCGACCCCGGG
TAAAATGTTATGGTAAGCATGCACAGTTTGCAGTCTACAGTTTTTTTATGTAGCACAAAATAGGTGTACCTTTATAAGTACATTCAATTT
TATGATTTACATTTATCATGTAATTTTTAAAAAAATCCATCTATCTAGGATATGTTGATACAAAGTCTGCTTTTGCTATTCTTTTTGCTT
AAATACTCCTATCATTTTCTGAATTACTTGGTATTTAGAACTCCTAGCACCACGGGGAAGAATAGAGGTATCATCAAACGTGGCAAATTT
TCTTTCAGGAATAATAAAGAGCATGATTCCACAGCTTTTCTGGGATGTTTGAGATTCTTTTTTAGTACTAAGCAAAATTCTCATCACAGA
ATGTAGCCCAGGCCAATTTATAACTAAATCTCTATTTGTTCAGATGATGCTTCTAAAACAGCATTGATAGGTTAAAGAAGCTTGGTATTT
TTAATTTACTTCAATGATTAGCTCAGTTGCTTAACTGGAGTTTTAATCCTGTGATATGTACATTGGATTCATGACTGTGCAGCATTTTTA
GTTATGTGGTGTTTGGCAGAATGACAATAAGGTTTTCCCCCATTTTGGTTTCAGGAGGACATGAATAGTGTGTTTATTGTAACTCCTCAT
ACACTTTTAAAACCAACATCTTTTTTCATAAATGTTGGTAGTGTTTGTCCAGGTACCTTAACTGTAGCTTGTGTAATGTTGATGAATATC
TGTATCTTACGGCTTCCATAATGGCTAGTTGATATTCAAAAACCTATTTCTGTGTTTTGAGGGGTGGGGAAAAAAAACACTAAGTGATAA
TTTGAAAAAGGCATATTGCTTCCAGATTCTGATGTGTGAGGGAAAATACTGTCACAATGAAAATCTTGACAATTTACTTAACAAGTAACC
AGTAGTTCATCAAAACCAACTTGTACAGACTAATAAATCTTTTTCACAGTATTCAGTTTTCTCACCTCTTGCTATTGTATATTGTAGATT

>37216_37216_6_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000441000_RAB18_chr10_27815757_ENST00000535776_length(amino acids)=138AA_BP=37
MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGVDFKVKTISVDGNKAKLAIWENREVDRNEGLKFARKHSMLFIEASAKTCDGV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for HNRNPH3-RAB18


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for HNRNPH3-RAB18


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for HNRNPH3-RAB18


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC1838625Warburg Sjo Fledelius syndrome2CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneC3280203WARBURG MICRO SYNDROME 31GENOMICS_ENGLAND;UNIPROT