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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FAM73A-MYCBP2 (FusionGDB2 ID:HG374986TG23077)

Fusion Gene Summary for FAM73A-MYCBP2

check button Fusion gene summary
Fusion gene informationFusion gene name: FAM73A-MYCBP2
Fusion gene ID: hg374986tg23077
HgeneTgene
Gene symbol

FAM73A

MYCBP2

Gene ID

374986

23077

Gene namemitoguardin 1MYC binding protein 2
SynonymsFAM73AMyc-bp2|PAM|PHR1|Phr
Cytomap('FAM73A')('MYCBP2')

1p31.1

13q22.3

Type of geneprotein-codingprotein-coding
Descriptionmitoguardin 1family with sequence similarity 73, member Aprotein FAM73AE3 ubiquitin-protein ligase MYCBP2HighwireMYC binding protein 2, E3 ubiquitin protein ligasePAM/Highwire/RPM-1 protein 1RING-type E3 ubiquitin transferase MYCBP2myc-binding protein 2pam/highwire/rpm-1 proteinprotein associated with Myc
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000370791, ENST00000443751, 
Fusion gene scores* DoF score6 X 6 X 5=1807 X 9 X 4=252
# samples 68
** MAII scorelog2(6/180*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/252*10)=-1.65535182861255
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FAM73A [Title/Abstract] AND MYCBP2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFAM73A(78332076)-MYCBP2(77641999), # samples:1
Anticipated loss of major functional domain due to fusion event.FAM73A-MYCBP2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
FAM73A-MYCBP2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
FAM73A-MYCBP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
FAM73A-MYCBP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFAM73A

GO:0008053

mitochondrial fusion

26711011

TgeneMYCBP2

GO:0016567

protein ubiquitination

29643511

TgeneMYCBP2

GO:0031398

positive regulation of protein ubiquitination

20534529


check buttonFusion gene breakpoints across FAM73A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across MYCBP2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-Cancer5263NFAM73Achr1

78332076

+MYCBP2chr13

77641999

-


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Fusion Gene ORF analysis for FAM73A-MYCBP2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000370791ENST00000360084FAM73Achr1

78332076

+MYCBP2chr13

77641999

-
5CDS-intronENST00000370791ENST00000482517FAM73Achr1

78332076

+MYCBP2chr13

77641999

-
5CDS-intronENST00000443751ENST00000360084FAM73Achr1

78332076

+MYCBP2chr13

77641999

-
5CDS-intronENST00000443751ENST00000482517FAM73Achr1

78332076

+MYCBP2chr13

77641999

-
In-frameENST00000370791ENST00000357337FAM73Achr1

78332076

+MYCBP2chr13

77641999

-
In-frameENST00000370791ENST00000407578FAM73Achr1

78332076

+MYCBP2chr13

77641999

-
In-frameENST00000370791ENST00000544440FAM73Achr1

78332076

+MYCBP2chr13

77641999

-
In-frameENST00000443751ENST00000357337FAM73Achr1

78332076

+MYCBP2chr13

77641999

-
In-frameENST00000443751ENST00000407578FAM73Achr1

78332076

+MYCBP2chr13

77641999

-
In-frameENST00000443751ENST00000544440FAM73Achr1

78332076

+MYCBP2chr13

77641999

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000370791FAM73Achr178332076+ENST00000544440MYCBP2chr1377641999-418215953234601142
ENST00000370791FAM73Achr178332076+ENST00000407578MYCBP2chr1377641999-418215953234601142
ENST00000370791FAM73Achr178332076+ENST00000357337MYCBP2chr1377641999-418115953234601142
ENST00000443751FAM73Achr178332076+ENST00000544440MYCBP2chr1377641999-40431456733211104
ENST00000443751FAM73Achr178332076+ENST00000407578MYCBP2chr1377641999-40431456733211104
ENST00000443751FAM73Achr178332076+ENST00000357337MYCBP2chr1377641999-40421456733211104

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000370791ENST00000544440FAM73Achr178332076+MYCBP2chr1377641999-0.0001865410.9998135
ENST00000370791ENST00000407578FAM73Achr178332076+MYCBP2chr1377641999-0.0001865410.9998135
ENST00000370791ENST00000357337FAM73Achr178332076+MYCBP2chr1377641999-0.0001862560.99981374
ENST00000443751ENST00000544440FAM73Achr178332076+MYCBP2chr1377641999-0.0001820220.999818
ENST00000443751ENST00000407578FAM73Achr178332076+MYCBP2chr1377641999-0.0001820220.999818
ENST00000443751ENST00000357337FAM73Achr178332076+MYCBP2chr1377641999-0.0001817040.99981827

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Fusion Genomic Features for FAM73A-MYCBP2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for FAM73A-MYCBP2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:78332076/chr13:77641999)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFAM73Achr1:78332076chr13:77641999ENST00000370791+141670_90521633.0TransmembraneHelical
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000035733770844539_467640194641.0RegionTandem cysteine domain
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000054444069834539_467640194641.0RegionTandem cysteine domain
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000035733770844428_447940194641.0Zinc fingerRING-type%3B atypical
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000054444069834428_447940194641.0Zinc fingerRING-type%3B atypical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMYCBP2chr1:78332076chr13:77641999ENST000003573377084103_12640194641.0Compositional biasLys-rich
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000035733770842720_284440194641.0Compositional biasSer-rich
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000035733770843194_321540194641.0Compositional biasLys-rich
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000035733770843262_329340194641.0Compositional biasNote=Gly-rich
TgeneMYCBP2chr1:78332076chr13:77641999ENST000003573377084766_81440194641.0Compositional biasCys-rich
TgeneMYCBP2chr1:78332076chr13:77641999ENST000005444406983103_12640194641.0Compositional biasLys-rich
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000054444069832720_284440194641.0Compositional biasSer-rich
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000054444069833194_321540194641.0Compositional biasLys-rich
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000054444069833262_329340194641.0Compositional biasNote=Gly-rich
TgeneMYCBP2chr1:78332076chr13:77641999ENST000005444406983766_81440194641.0Compositional biasCys-rich
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000035733770843719_389740194641.0DomainDOC
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000054444069833719_389740194641.0DomainDOC
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000035733770841235_138640194641.0RegionPHR domain 1
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000035733770841726_188440194641.0RegionPHR domain 2
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000035733770842022_255040194641.0RegionRAE1 binding
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000054444069831235_138640194641.0RegionPHR domain 1
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000054444069831726_188440194641.0RegionPHR domain 2
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000054444069832022_255040194641.0RegionRAE1 binding
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000035733770841010_106640194641.0RepeatRCC1 5
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000035733770842341_244340194641.0RepeatFilamin
TgeneMYCBP2chr1:78332076chr13:77641999ENST000003573377084600_65540194641.0RepeatRCC1 1
TgeneMYCBP2chr1:78332076chr13:77641999ENST000003573377084699_75540194641.0RepeatRCC1 2
TgeneMYCBP2chr1:78332076chr13:77641999ENST000003573377084907_95740194641.0RepeatRCC1 3
TgeneMYCBP2chr1:78332076chr13:77641999ENST000003573377084958_100840194641.0RepeatRCC1 4
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000054444069831010_106640194641.0RepeatRCC1 5
TgeneMYCBP2chr1:78332076chr13:77641999ENST0000054444069832341_244340194641.0RepeatFilamin
TgeneMYCBP2chr1:78332076chr13:77641999ENST000005444406983600_65540194641.0RepeatRCC1 1
TgeneMYCBP2chr1:78332076chr13:77641999ENST000005444406983699_75540194641.0RepeatRCC1 2
TgeneMYCBP2chr1:78332076chr13:77641999ENST000005444406983907_95740194641.0RepeatRCC1 3
TgeneMYCBP2chr1:78332076chr13:77641999ENST000005444406983958_100840194641.0RepeatRCC1 4


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Fusion Gene Sequence for FAM73A-MYCBP2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>29189_29189_1_FAM73A-MYCBP2_FAM73A_chr1_78332076_ENST00000370791_MYCBP2_chr13_77641999_ENST00000357337_length(transcript)=4181nt_BP=1595nt
ACTCCTGACCCCGGAAGGACTCCGCCTTCTCCATGTCAGACTGCTGCTCAGCGCCAGGCATCAGCTGGGAAGCTGGCGTGGGCAGGCCAG
CTGTACCTGGCCTGGAGCTCCAGATTAGAAGAGGAGCCATGTCAGAAGAAACAGTAAGTGAATCACAGTTTTCCTTGAAGACAGCAGCGC
TAAGAGTGTTTGATCTTCCTCTGACTTGGTACTATTCTCTCTCCCAGATCAAATTTTCTCCGGTGGCTAAAAAGTTGTTTGTGGTAACTG
CAGTGAGTGCTATATCTGTAATTTTTCTGGCTCATCACTTTAAAAGAAAACGTGGAAAGAAGAAAGGAAAAATATTACCATGGGAACCAG
AGCACCTCATACTTGAATACACTAAAAGAGCAGCATCAGACAAAGGTTCAAGTTGTTCCAGTAGCAGACAGAATTTGACATTATCTTTAA
GTTCTACCAAAGACAAAGGATCTCAAGTTTGTAACTATGCTAATGGAGGACTTTTCAGTAAATATTCAGGTTCTGCACAGAGTTTGGCCT
CTGTCCAGAGTGTCAATTCTTGTCATAGCTGCGCTTGTGGCAATTCTAATTCCTGGGACAAAGCAGATGAAGATGATATTAAACTTGTTA
ATATTCCTGTGACTACTCCAGAGAACTTATACTTAATGGGTATGGAATTGTTTGAAGAGGCATTGCGTCGATGGGAACAAGCTCTGACCT
TTCGCAATAGACAGGCTGAAGATGAAGCCTGTGGTTCCATTAAACTGGGTGCAGGAGATGCCATTGCTGAAGAAAATGTAGATGATATTA
TTAGTACTGAATTTATCCATAAACTCGAAGCTCTGCTGCAAAGAGCCTATCGTCTCCAAGAGGAGTTTGAAGCTACCCTTGGGGCATCTG
ATCCTAATTCCCTTGCTGATGATATTGATAAAGATACAGATATCACCATGAAGGGTAATGTGGAAGACTTTGGCCTGCGAGACACCTTGA
GCATCGCATCCACGGATTCCTTTGCTTCCGCAGCAGAGCTTGCAGAACACAGAGAAGTACGGCATACCTACAGCCTGGAGTCCCTTTGTC
ACTGCCCATTTTACGAGGAAGCCATGCATTTAGTTGAAGAAGGAAAAATTTACTCCAGAGTACTGAGAACTGAAATGTTGGAGTGCCTAG
GAGACAGTGATTTTCTTGCCAAACTTCACTGTATTCGACAGGCTTTTCAGGTAATTCTTTCAGAATCAGCTAACAGGATATTCCTCGCTG
AGAGCGGAAGGAAAATTTTATCAGCTTTAATTGTGAAAGCACGAAAGAATCCAAAGAAGTTTGAAGATGTTTTTGATGAAATGATCTATT
TTTTAGAGCAGACCGATCACTGGGGTAGTACTGAAATGGAACTTGCTGCTAGAGGGGTGAAAAATCTAAATTTTTATGATGTTGTTCTGG
ATTTTATATTAATGGACTCCTTTGAAGATTTGGAAAACCCACCCACATCCATACAGAATGTAGTAAATAATCGATGGCTAAACTCATCCT
TCAAAGAAACAGCTGTGGCTTCAAGTTGTTGGTCGGTGCTGAAACAGAAAAGACAACAGATGAAGGTAACCTCTTTACTAAGAAGAGTTT
TGCCTGAAGTAACCCCTAGTCGTCTGGCCAGCATCATAGGAGTGAAATCCCTCCCCCCAGCAGATATCAGTGATATCATTCACTCAACAG
AGAAAGGAGACTGGAATAAGCTGGGTATCTTGGACATGTTTCTAGGATGCATTGCCAAAGCACTCACTGTACAGCTAAAAGCCAAAGGAA
CCACCATCACTGGAACAGCTGGTACCACTGTGGGCAAAGGAGTTACAACAGTTACTCTTCCGATGATTTTCAATTCCAGTTATCTCCGAC
GAGGTGAAAGTCATTGGTGGATGAAGGGCTCAACCCCTACCCAGATCTCAGAGATCATCATTAAACTTATCAAGGATATGGCAGCAGGTC
ATCTGTCAGAAGCTTGGTCCCGAGTGACAAAAAATGCTATTGCAGAAACCATCATTGCCTTGACCAAGATGGAAGAAGAATTTAGGTCTC
CAGTGAGATGTATTGCAACAACTAGACTCTGGCTTGCTCTCGCATCCCTATGTGTTCTTGATCAGGACCACGTAGATCGTCTCTCCTCGG
GGAGATGGATGGGAAAGGATGGACAACAAAAACAAATGCCTATGTGTGATAACCATGATGATGGTGAAACTGCAGCAATCATTTTATGCA
ATGTCTGTGGAAATTTATGTACAGACTGTGACAGATTCCTTCACCTTCATCGAAGAACCAAAACTCATCAAAGACAGGTCTTCAAAGAAG
AAGAAGAAGCTATAAAGGTTGACCTTCATGAAGGTTGTGGTAGAACCAAATTGTTCTGGTTGATGGCACTGGCAGATTCTAAAACAATGA
AGGCAATGGTGGAATTCCGAGAACACACAGGCAAACCCACCACGAGTAGCTCAGAAGCATGTCGCTTCTGTGGTTCCAGGAGTGGAACAG
AGTTATCTGCTGTTGGCAGTGTTTGTTCTGATGCAGATTGCCAGGAATACGCTAAGATAGCCTGTAGTAAGACGCATCCTTGTGGCCATC
CATGCGGGGGTGTTAAAAACGAAGAGCACTGTCTGCCCTGTCTACACGGCTGTGACAAAAGTGCCACAAGCCTGAAGCAAGACGCCGATG
ACATGTGCATGATATGTTTCACCGAAGCGCTCTCGGCAGCACCAGCCATTCAGCTGGATTGTAGTCACATATTCCACTTACAGTGCTGTC
GGCGAGTATTAGAAAATCGATGGCTTGGCCCAAGGATAACATTTGGATTTATATCTTGTCCCATTTGCAAGAACAAAATTAATCACATAG
TACTAAAAGACCTACTTGATCCAATAAAAGAACTCTATGAGGATGTCAGAAGAAAAGCCTTAATGAGATTGGAATATGAAGGTCTGCATA
AGAGTGAAGCTATCACAACTCCTGGTGTGAGGTTTTATAATGACCCAGCTGGCTATGCAATGAATAGATATGCATATTATGTGTGCTACA
AATGCAGAAAGGCATATTTTGGTGGTGAAGCTCGCTGCGATGCTGAGGCTGGACGGGGAGATGATTATGATCCCAGAGAGCTCATTTGTG
GTGCCTGTTCTGATGTTTCCAGGGCTCAGATGTGTCCCAAACATGGCACAGACTTTTTGGAATATAAATGTCGCTACTGCTGTTCAGTGG
CTGTTTTTTTCTGTTTTGGAACAACACATTTTTGTAATGCTTGTCATGATGATTTTCAAAGAATGACTAGCATTCCTAAGGAAGAACTAC
CACACTGTCCTGCAGGTCCCAAAGGCAAGCAGTTAGAAGGAACTGAATGTCCACTCCATGTTGTTCATCCACCCACTGGGGAAGAGTTTG
CTCTGGGATGTGGAGTGTGCAGAAATGCCCACACTTTTTAGAACACGCAGATCCTTTGTCTACAGAGAGAAAAATTGCCTTCATCCCCCA
AGAGGATGCGGTGAAGTTTAAACTCTGCTCAGGATAAGGACGGGACCATTTTTACATCCATGAAAATGAACCATTCACAGTGCAAGAAGG
ATACCAAATACCATGTACATAATTCTTGCTATGAAAAGTTTCCCCATTATTTTGGTTTATCTTCTTTTGAACAAATGACATCAAACTTGT
GAGGTGTTTGCATGTGGCCATTACCGTCATTGGCCTGTGAAGCATTGGACATTTATAGATAATTGATATAAAAGAATCGCCATGCCCATG
GACTAAGAACGATGCTGGCTTTCAAGCAAAAAAGAAAAATAATCATTGTTTATTGTATACTGCCTTTTTGTAATCCTGTACAATTGCATC
ACGGGTGGGGATAAAAAGAGGAATATTCTGGTTTATTTCCTAGACTGTTATTTAAAAAAAAAAAAAACATTGTGTTAGGACAGCATATAA
ATGTAATAAGTATCACACTGTATATAAACATATCAATGTTTGTCCTGTATAAGAATTACTAAATTACAAATGCAATTTCATTTAAACTTC
TAGGTTAAGTTTGAGCCTGAAATTTTAATGAAGTGCAATACTGAGTGTGCCTCATTATCTTGCAGCTGTAAACATATTGGAATGTACATG

>29189_29189_1_FAM73A-MYCBP2_FAM73A_chr1_78332076_ENST00000370791_MYCBP2_chr13_77641999_ENST00000357337_length(amino acids)=1142AA_BP=521
MSDCCSAPGISWEAGVGRPAVPGLELQIRRGAMSEETVSESQFSLKTAALRVFDLPLTWYYSLSQIKFSPVAKKLFVVTAVSAISVIFLA
HHFKRKRGKKKGKILPWEPEHLILEYTKRAASDKGSSCSSSRQNLTLSLSSTKDKGSQVCNYANGGLFSKYSGSAQSLASVQSVNSCHSC
ACGNSNSWDKADEDDIKLVNIPVTTPENLYLMGMELFEEALRRWEQALTFRNRQAEDEACGSIKLGAGDAIAEENVDDIISTEFIHKLEA
LLQRAYRLQEEFEATLGASDPNSLADDIDKDTDITMKGNVEDFGLRDTLSIASTDSFASAAELAEHREVRHTYSLESLCHCPFYEEAMHL
VEEGKIYSRVLRTEMLECLGDSDFLAKLHCIRQAFQVILSESANRIFLAESGRKILSALIVKARKNPKKFEDVFDEMIYFLEQTDHWGST
EMELAARGVKNLNFYDVVLDFILMDSFEDLENPPTSIQNVVNNRWLNSSFKETAVASSCWSVLKQKRQQMKVTSLLRRVLPEVTPSRLAS
IIGVKSLPPADISDIIHSTEKGDWNKLGILDMFLGCIAKALTVQLKAKGTTITGTAGTTVGKGVTTVTLPMIFNSSYLRRGESHWWMKGS
TPTQISEIIIKLIKDMAAGHLSEAWSRVTKNAIAETIIALTKMEEEFRSPVRCIATTRLWLALASLCVLDQDHVDRLSSGRWMGKDGQQK
QMPMCDNHDDGETAAIILCNVCGNLCTDCDRFLHLHRRTKTHQRQVFKEEEEAIKVDLHEGCGRTKLFWLMALADSKTMKAMVEFREHTG
KPTTSSSEACRFCGSRSGTELSAVGSVCSDADCQEYAKIACSKTHPCGHPCGGVKNEEHCLPCLHGCDKSATSLKQDADDMCMICFTEAL
SAAPAIQLDCSHIFHLQCCRRVLENRWLGPRITFGFISCPICKNKINHIVLKDLLDPIKELYEDVRRKALMRLEYEGLHKSEAITTPGVR
FYNDPAGYAMNRYAYYVCYKCRKAYFGGEARCDAEAGRGDDYDPRELICGACSDVSRAQMCPKHGTDFLEYKCRYCCSVAVFFCFGTTHF

--------------------------------------------------------------
>29189_29189_2_FAM73A-MYCBP2_FAM73A_chr1_78332076_ENST00000370791_MYCBP2_chr13_77641999_ENST00000407578_length(transcript)=4182nt_BP=1595nt
ACTCCTGACCCCGGAAGGACTCCGCCTTCTCCATGTCAGACTGCTGCTCAGCGCCAGGCATCAGCTGGGAAGCTGGCGTGGGCAGGCCAG
CTGTACCTGGCCTGGAGCTCCAGATTAGAAGAGGAGCCATGTCAGAAGAAACAGTAAGTGAATCACAGTTTTCCTTGAAGACAGCAGCGC
TAAGAGTGTTTGATCTTCCTCTGACTTGGTACTATTCTCTCTCCCAGATCAAATTTTCTCCGGTGGCTAAAAAGTTGTTTGTGGTAACTG
CAGTGAGTGCTATATCTGTAATTTTTCTGGCTCATCACTTTAAAAGAAAACGTGGAAAGAAGAAAGGAAAAATATTACCATGGGAACCAG
AGCACCTCATACTTGAATACACTAAAAGAGCAGCATCAGACAAAGGTTCAAGTTGTTCCAGTAGCAGACAGAATTTGACATTATCTTTAA
GTTCTACCAAAGACAAAGGATCTCAAGTTTGTAACTATGCTAATGGAGGACTTTTCAGTAAATATTCAGGTTCTGCACAGAGTTTGGCCT
CTGTCCAGAGTGTCAATTCTTGTCATAGCTGCGCTTGTGGCAATTCTAATTCCTGGGACAAAGCAGATGAAGATGATATTAAACTTGTTA
ATATTCCTGTGACTACTCCAGAGAACTTATACTTAATGGGTATGGAATTGTTTGAAGAGGCATTGCGTCGATGGGAACAAGCTCTGACCT
TTCGCAATAGACAGGCTGAAGATGAAGCCTGTGGTTCCATTAAACTGGGTGCAGGAGATGCCATTGCTGAAGAAAATGTAGATGATATTA
TTAGTACTGAATTTATCCATAAACTCGAAGCTCTGCTGCAAAGAGCCTATCGTCTCCAAGAGGAGTTTGAAGCTACCCTTGGGGCATCTG
ATCCTAATTCCCTTGCTGATGATATTGATAAAGATACAGATATCACCATGAAGGGTAATGTGGAAGACTTTGGCCTGCGAGACACCTTGA
GCATCGCATCCACGGATTCCTTTGCTTCCGCAGCAGAGCTTGCAGAACACAGAGAAGTACGGCATACCTACAGCCTGGAGTCCCTTTGTC
ACTGCCCATTTTACGAGGAAGCCATGCATTTAGTTGAAGAAGGAAAAATTTACTCCAGAGTACTGAGAACTGAAATGTTGGAGTGCCTAG
GAGACAGTGATTTTCTTGCCAAACTTCACTGTATTCGACAGGCTTTTCAGGTAATTCTTTCAGAATCAGCTAACAGGATATTCCTCGCTG
AGAGCGGAAGGAAAATTTTATCAGCTTTAATTGTGAAAGCACGAAAGAATCCAAAGAAGTTTGAAGATGTTTTTGATGAAATGATCTATT
TTTTAGAGCAGACCGATCACTGGGGTAGTACTGAAATGGAACTTGCTGCTAGAGGGGTGAAAAATCTAAATTTTTATGATGTTGTTCTGG
ATTTTATATTAATGGACTCCTTTGAAGATTTGGAAAACCCACCCACATCCATACAGAATGTAGTAAATAATCGATGGCTAAACTCATCCT
TCAAAGAAACAGCTGTGGCTTCAAGTTGTTGGTCGGTGCTGAAACAGAAAAGACAACAGATGAAGGTAACCTCTTTACTAAGAAGAGTTT
TGCCTGAAGTAACCCCTAGTCGTCTGGCCAGCATCATAGGAGTGAAATCCCTCCCCCCAGCAGATATCAGTGATATCATTCACTCAACAG
AGAAAGGAGACTGGAATAAGCTGGGTATCTTGGACATGTTTCTAGGATGCATTGCCAAAGCACTCACTGTACAGCTAAAAGCCAAAGGAA
CCACCATCACTGGAACAGCTGGTACCACTGTGGGCAAAGGAGTTACAACAGTTACTCTTCCGATGATTTTCAATTCCAGTTATCTCCGAC
GAGGTGAAAGTCATTGGTGGATGAAGGGCTCAACCCCTACCCAGATCTCAGAGATCATCATTAAACTTATCAAGGATATGGCAGCAGGTC
ATCTGTCAGAAGCTTGGTCCCGAGTGACAAAAAATGCTATTGCAGAAACCATCATTGCCTTGACCAAGATGGAAGAAGAATTTAGGTCTC
CAGTGAGATGTATTGCAACAACTAGACTCTGGCTTGCTCTCGCATCCCTATGTGTTCTTGATCAGGACCACGTAGATCGTCTCTCCTCGG
GGAGATGGATGGGAAAGGATGGACAACAAAAACAAATGCCTATGTGTGATAACCATGATGATGGTGAAACTGCAGCAATCATTTTATGCA
ATGTCTGTGGAAATTTATGTACAGACTGTGACAGATTCCTTCACCTTCATCGAAGAACCAAAACTCATCAAAGACAGGTCTTCAAAGAAG
AAGAAGAAGCTATAAAGGTTGACCTTCATGAAGGTTGTGGTAGAACCAAATTGTTCTGGTTGATGGCACTGGCAGATTCTAAAACAATGA
AGGCAATGGTGGAATTCCGAGAACACACAGGCAAACCCACCACGAGTAGCTCAGAAGCATGTCGCTTCTGTGGTTCCAGGAGTGGAACAG
AGTTATCTGCTGTTGGCAGTGTTTGTTCTGATGCAGATTGCCAGGAATACGCTAAGATAGCCTGTAGTAAGACGCATCCTTGTGGCCATC
CATGCGGGGGTGTTAAAAACGAAGAGCACTGTCTGCCCTGTCTACACGGCTGTGACAAAAGTGCCACAAGCCTGAAGCAAGACGCCGATG
ACATGTGCATGATATGTTTCACCGAAGCGCTCTCGGCAGCACCAGCCATTCAGCTGGATTGTAGTCACATATTCCACTTACAGTGCTGTC
GGCGAGTATTAGAAAATCGATGGCTTGGCCCAAGGATAACATTTGGATTTATATCTTGTCCCATTTGCAAGAACAAAATTAATCACATAG
TACTAAAAGACCTACTTGATCCAATAAAAGAACTCTATGAGGATGTCAGAAGAAAAGCCTTAATGAGATTGGAATATGAAGGTCTGCATA
AGAGTGAAGCTATCACAACTCCTGGTGTGAGGTTTTATAATGACCCAGCTGGCTATGCAATGAATAGATATGCATATTATGTGTGCTACA
AATGCAGAAAGGCATATTTTGGTGGTGAAGCTCGCTGCGATGCTGAGGCTGGACGGGGAGATGATTATGATCCCAGAGAGCTCATTTGTG
GTGCCTGTTCTGATGTTTCCAGGGCTCAGATGTGTCCCAAACATGGCACAGACTTTTTGGAATATAAATGTCGCTACTGCTGTTCAGTGG
CTGTTTTTTTCTGTTTTGGAACAACACATTTTTGTAATGCTTGTCATGATGATTTTCAAAGAATGACTAGCATTCCTAAGGAAGAACTAC
CACACTGTCCTGCAGGTCCCAAAGGCAAGCAGTTAGAAGGAACTGAATGTCCACTCCATGTTGTTCATCCACCCACTGGGGAAGAGTTTG
CTCTGGGATGTGGAGTGTGCAGAAATGCCCACACTTTTTAGAACACGCAGATCCTTTGTCTACAGAGAGAAAAATTGCCTTCATCCCCCA
AGAGGATGCGGTGAAGTTTAAACTCTGCTCAGGATAAGGACGGGACCATTTTTACATCCATGAAAATGAACCATTCACAGTGCAAGAAGG
ATACCAAATACCATGTACATAATTCTTGCTATGAAAAGTTTCCCCATTATTTTGGTTTATCTTCTTTTGAACAAATGACATCAAACTTGT
GAGGTGTTTGCATGTGGCCATTACCGTCATTGGCCTGTGAAGCATTGGACATTTATAGATAATTGATATAAAAGAATCGCCATGCCCATG
GACTAAGAACGATGCTGGCTTTCAAGCAAAAAAGAAAAATAATCATTGTTTATTGTATACTGCCTTTTTGTAATCCTGTACAATTGCATC
ACGGGTGGGGATAAAAAGAGGAATATTCTGGTTTATTTCCTAGACTGTTATTTAAAAAAAAAAAAAACATTGTGTTAGGACAGCATATAA
ATGTAATAAGTATCACACTGTATATAAACATATCAATGTTTGTCCTGTATAAGAATTACTAAATTACAAATGCAATTTCATTTAAACTTC
TAGGTTAAGTTTGAGCCTGAAATTTTAATGAAGTGCAATACTGAGTGTGCCTCATTATCTTGCAGCTGTAAACATATTGGAATGTACATG

>29189_29189_2_FAM73A-MYCBP2_FAM73A_chr1_78332076_ENST00000370791_MYCBP2_chr13_77641999_ENST00000407578_length(amino acids)=1142AA_BP=521
MSDCCSAPGISWEAGVGRPAVPGLELQIRRGAMSEETVSESQFSLKTAALRVFDLPLTWYYSLSQIKFSPVAKKLFVVTAVSAISVIFLA
HHFKRKRGKKKGKILPWEPEHLILEYTKRAASDKGSSCSSSRQNLTLSLSSTKDKGSQVCNYANGGLFSKYSGSAQSLASVQSVNSCHSC
ACGNSNSWDKADEDDIKLVNIPVTTPENLYLMGMELFEEALRRWEQALTFRNRQAEDEACGSIKLGAGDAIAEENVDDIISTEFIHKLEA
LLQRAYRLQEEFEATLGASDPNSLADDIDKDTDITMKGNVEDFGLRDTLSIASTDSFASAAELAEHREVRHTYSLESLCHCPFYEEAMHL
VEEGKIYSRVLRTEMLECLGDSDFLAKLHCIRQAFQVILSESANRIFLAESGRKILSALIVKARKNPKKFEDVFDEMIYFLEQTDHWGST
EMELAARGVKNLNFYDVVLDFILMDSFEDLENPPTSIQNVVNNRWLNSSFKETAVASSCWSVLKQKRQQMKVTSLLRRVLPEVTPSRLAS
IIGVKSLPPADISDIIHSTEKGDWNKLGILDMFLGCIAKALTVQLKAKGTTITGTAGTTVGKGVTTVTLPMIFNSSYLRRGESHWWMKGS
TPTQISEIIIKLIKDMAAGHLSEAWSRVTKNAIAETIIALTKMEEEFRSPVRCIATTRLWLALASLCVLDQDHVDRLSSGRWMGKDGQQK
QMPMCDNHDDGETAAIILCNVCGNLCTDCDRFLHLHRRTKTHQRQVFKEEEEAIKVDLHEGCGRTKLFWLMALADSKTMKAMVEFREHTG
KPTTSSSEACRFCGSRSGTELSAVGSVCSDADCQEYAKIACSKTHPCGHPCGGVKNEEHCLPCLHGCDKSATSLKQDADDMCMICFTEAL
SAAPAIQLDCSHIFHLQCCRRVLENRWLGPRITFGFISCPICKNKINHIVLKDLLDPIKELYEDVRRKALMRLEYEGLHKSEAITTPGVR
FYNDPAGYAMNRYAYYVCYKCRKAYFGGEARCDAEAGRGDDYDPRELICGACSDVSRAQMCPKHGTDFLEYKCRYCCSVAVFFCFGTTHF

--------------------------------------------------------------
>29189_29189_3_FAM73A-MYCBP2_FAM73A_chr1_78332076_ENST00000370791_MYCBP2_chr13_77641999_ENST00000544440_length(transcript)=4182nt_BP=1595nt
ACTCCTGACCCCGGAAGGACTCCGCCTTCTCCATGTCAGACTGCTGCTCAGCGCCAGGCATCAGCTGGGAAGCTGGCGTGGGCAGGCCAG
CTGTACCTGGCCTGGAGCTCCAGATTAGAAGAGGAGCCATGTCAGAAGAAACAGTAAGTGAATCACAGTTTTCCTTGAAGACAGCAGCGC
TAAGAGTGTTTGATCTTCCTCTGACTTGGTACTATTCTCTCTCCCAGATCAAATTTTCTCCGGTGGCTAAAAAGTTGTTTGTGGTAACTG
CAGTGAGTGCTATATCTGTAATTTTTCTGGCTCATCACTTTAAAAGAAAACGTGGAAAGAAGAAAGGAAAAATATTACCATGGGAACCAG
AGCACCTCATACTTGAATACACTAAAAGAGCAGCATCAGACAAAGGTTCAAGTTGTTCCAGTAGCAGACAGAATTTGACATTATCTTTAA
GTTCTACCAAAGACAAAGGATCTCAAGTTTGTAACTATGCTAATGGAGGACTTTTCAGTAAATATTCAGGTTCTGCACAGAGTTTGGCCT
CTGTCCAGAGTGTCAATTCTTGTCATAGCTGCGCTTGTGGCAATTCTAATTCCTGGGACAAAGCAGATGAAGATGATATTAAACTTGTTA
ATATTCCTGTGACTACTCCAGAGAACTTATACTTAATGGGTATGGAATTGTTTGAAGAGGCATTGCGTCGATGGGAACAAGCTCTGACCT
TTCGCAATAGACAGGCTGAAGATGAAGCCTGTGGTTCCATTAAACTGGGTGCAGGAGATGCCATTGCTGAAGAAAATGTAGATGATATTA
TTAGTACTGAATTTATCCATAAACTCGAAGCTCTGCTGCAAAGAGCCTATCGTCTCCAAGAGGAGTTTGAAGCTACCCTTGGGGCATCTG
ATCCTAATTCCCTTGCTGATGATATTGATAAAGATACAGATATCACCATGAAGGGTAATGTGGAAGACTTTGGCCTGCGAGACACCTTGA
GCATCGCATCCACGGATTCCTTTGCTTCCGCAGCAGAGCTTGCAGAACACAGAGAAGTACGGCATACCTACAGCCTGGAGTCCCTTTGTC
ACTGCCCATTTTACGAGGAAGCCATGCATTTAGTTGAAGAAGGAAAAATTTACTCCAGAGTACTGAGAACTGAAATGTTGGAGTGCCTAG
GAGACAGTGATTTTCTTGCCAAACTTCACTGTATTCGACAGGCTTTTCAGGTAATTCTTTCAGAATCAGCTAACAGGATATTCCTCGCTG
AGAGCGGAAGGAAAATTTTATCAGCTTTAATTGTGAAAGCACGAAAGAATCCAAAGAAGTTTGAAGATGTTTTTGATGAAATGATCTATT
TTTTAGAGCAGACCGATCACTGGGGTAGTACTGAAATGGAACTTGCTGCTAGAGGGGTGAAAAATCTAAATTTTTATGATGTTGTTCTGG
ATTTTATATTAATGGACTCCTTTGAAGATTTGGAAAACCCACCCACATCCATACAGAATGTAGTAAATAATCGATGGCTAAACTCATCCT
TCAAAGAAACAGCTGTGGCTTCAAGTTGTTGGTCGGTGCTGAAACAGAAAAGACAACAGATGAAGGTAACCTCTTTACTAAGAAGAGTTT
TGCCTGAAGTAACCCCTAGTCGTCTGGCCAGCATCATAGGAGTGAAATCCCTCCCCCCAGCAGATATCAGTGATATCATTCACTCAACAG
AGAAAGGAGACTGGAATAAGCTGGGTATCTTGGACATGTTTCTAGGATGCATTGCCAAAGCACTCACTGTACAGCTAAAAGCCAAAGGAA
CCACCATCACTGGAACAGCTGGTACCACTGTGGGCAAAGGAGTTACAACAGTTACTCTTCCGATGATTTTCAATTCCAGTTATCTCCGAC
GAGGTGAAAGTCATTGGTGGATGAAGGGCTCAACCCCTACCCAGATCTCAGAGATCATCATTAAACTTATCAAGGATATGGCAGCAGGTC
ATCTGTCAGAAGCTTGGTCCCGAGTGACAAAAAATGCTATTGCAGAAACCATCATTGCCTTGACCAAGATGGAAGAAGAATTTAGGTCTC
CAGTGAGATGTATTGCAACAACTAGACTCTGGCTTGCTCTCGCATCCCTATGTGTTCTTGATCAGGACCACGTAGATCGTCTCTCCTCGG
GGAGATGGATGGGAAAGGATGGACAACAAAAACAAATGCCTATGTGTGATAACCATGATGATGGTGAAACTGCAGCAATCATTTTATGCA
ATGTCTGTGGAAATTTATGTACAGACTGTGACAGATTCCTTCACCTTCATCGAAGAACCAAAACTCATCAAAGACAGGTCTTCAAAGAAG
AAGAAGAAGCTATAAAGGTTGACCTTCATGAAGGTTGTGGTAGAACCAAATTGTTCTGGTTGATGGCACTGGCAGATTCTAAAACAATGA
AGGCAATGGTGGAATTCCGAGAACACACAGGCAAACCCACCACGAGTAGCTCAGAAGCATGTCGCTTCTGTGGTTCCAGGAGTGGAACAG
AGTTATCTGCTGTTGGCAGTGTTTGTTCTGATGCAGATTGCCAGGAATACGCTAAGATAGCCTGTAGTAAGACGCATCCTTGTGGCCATC
CATGCGGGGGTGTTAAAAACGAAGAGCACTGTCTGCCCTGTCTACACGGCTGTGACAAAAGTGCCACAAGCCTGAAGCAAGACGCCGATG
ACATGTGCATGATATGTTTCACCGAAGCGCTCTCGGCAGCACCAGCCATTCAGCTGGATTGTAGTCACATATTCCACTTACAGTGCTGTC
GGCGAGTATTAGAAAATCGATGGCTTGGCCCAAGGATAACATTTGGATTTATATCTTGTCCCATTTGCAAGAACAAAATTAATCACATAG
TACTAAAAGACCTACTTGATCCAATAAAAGAACTCTATGAGGATGTCAGAAGAAAAGCCTTAATGAGATTGGAATATGAAGGTCTGCATA
AGAGTGAAGCTATCACAACTCCTGGTGTGAGGTTTTATAATGACCCAGCTGGCTATGCAATGAATAGATATGCATATTATGTGTGCTACA
AATGCAGAAAGGCATATTTTGGTGGTGAAGCTCGCTGCGATGCTGAGGCTGGACGGGGAGATGATTATGATCCCAGAGAGCTCATTTGTG
GTGCCTGTTCTGATGTTTCCAGGGCTCAGATGTGTCCCAAACATGGCACAGACTTTTTGGAATATAAATGTCGCTACTGCTGTTCAGTGG
CTGTTTTTTTCTGTTTTGGAACAACACATTTTTGTAATGCTTGTCATGATGATTTTCAAAGAATGACTAGCATTCCTAAGGAAGAACTAC
CACACTGTCCTGCAGGTCCCAAAGGCAAGCAGTTAGAAGGAACTGAATGTCCACTCCATGTTGTTCATCCACCCACTGGGGAAGAGTTTG
CTCTGGGATGTGGAGTGTGCAGAAATGCCCACACTTTTTAGAACACGCAGATCCTTTGTCTACAGAGAGAAAAATTGCCTTCATCCCCCA
AGAGGATGCGGTGAAGTTTAAACTCTGCTCAGGATAAGGACGGGACCATTTTTACATCCATGAAAATGAACCATTCACAGTGCAAGAAGG
ATACCAAATACCATGTACATAATTCTTGCTATGAAAAGTTTCCCCATTATTTTGGTTTATCTTCTTTTGAACAAATGACATCAAACTTGT
GAGGTGTTTGCATGTGGCCATTACCGTCATTGGCCTGTGAAGCATTGGACATTTATAGATAATTGATATAAAAGAATCGCCATGCCCATG
GACTAAGAACGATGCTGGCTTTCAAGCAAAAAAGAAAAATAATCATTGTTTATTGTATACTGCCTTTTTGTAATCCTGTACAATTGCATC
ACGGGTGGGGATAAAAAGAGGAATATTCTGGTTTATTTCCTAGACTGTTATTTAAAAAAAAAAAAAACATTGTGTTAGGACAGCATATAA
ATGTAATAAGTATCACACTGTATATAAACATATCAATGTTTGTCCTGTATAAGAATTACTAAATTACAAATGCAATTTCATTTAAACTTC
TAGGTTAAGTTTGAGCCTGAAATTTTAATGAAGTGCAATACTGAGTGTGCCTCATTATCTTGCAGCTGTAAACATATTGGAATGTACATG

>29189_29189_3_FAM73A-MYCBP2_FAM73A_chr1_78332076_ENST00000370791_MYCBP2_chr13_77641999_ENST00000544440_length(amino acids)=1142AA_BP=521
MSDCCSAPGISWEAGVGRPAVPGLELQIRRGAMSEETVSESQFSLKTAALRVFDLPLTWYYSLSQIKFSPVAKKLFVVTAVSAISVIFLA
HHFKRKRGKKKGKILPWEPEHLILEYTKRAASDKGSSCSSSRQNLTLSLSSTKDKGSQVCNYANGGLFSKYSGSAQSLASVQSVNSCHSC
ACGNSNSWDKADEDDIKLVNIPVTTPENLYLMGMELFEEALRRWEQALTFRNRQAEDEACGSIKLGAGDAIAEENVDDIISTEFIHKLEA
LLQRAYRLQEEFEATLGASDPNSLADDIDKDTDITMKGNVEDFGLRDTLSIASTDSFASAAELAEHREVRHTYSLESLCHCPFYEEAMHL
VEEGKIYSRVLRTEMLECLGDSDFLAKLHCIRQAFQVILSESANRIFLAESGRKILSALIVKARKNPKKFEDVFDEMIYFLEQTDHWGST
EMELAARGVKNLNFYDVVLDFILMDSFEDLENPPTSIQNVVNNRWLNSSFKETAVASSCWSVLKQKRQQMKVTSLLRRVLPEVTPSRLAS
IIGVKSLPPADISDIIHSTEKGDWNKLGILDMFLGCIAKALTVQLKAKGTTITGTAGTTVGKGVTTVTLPMIFNSSYLRRGESHWWMKGS
TPTQISEIIIKLIKDMAAGHLSEAWSRVTKNAIAETIIALTKMEEEFRSPVRCIATTRLWLALASLCVLDQDHVDRLSSGRWMGKDGQQK
QMPMCDNHDDGETAAIILCNVCGNLCTDCDRFLHLHRRTKTHQRQVFKEEEEAIKVDLHEGCGRTKLFWLMALADSKTMKAMVEFREHTG
KPTTSSSEACRFCGSRSGTELSAVGSVCSDADCQEYAKIACSKTHPCGHPCGGVKNEEHCLPCLHGCDKSATSLKQDADDMCMICFTEAL
SAAPAIQLDCSHIFHLQCCRRVLENRWLGPRITFGFISCPICKNKINHIVLKDLLDPIKELYEDVRRKALMRLEYEGLHKSEAITTPGVR
FYNDPAGYAMNRYAYYVCYKCRKAYFGGEARCDAEAGRGDDYDPRELICGACSDVSRAQMCPKHGTDFLEYKCRYCCSVAVFFCFGTTHF

--------------------------------------------------------------
>29189_29189_4_FAM73A-MYCBP2_FAM73A_chr1_78332076_ENST00000443751_MYCBP2_chr13_77641999_ENST00000357337_length(transcript)=4042nt_BP=1456nt
CTTCTCCATGTCAGACTGCTGCTCAGCGCCAGGCATCAGCTGGGAAGCTGGCGTGGGCAGGCCAGCTGTACCTGGCCTGGAGCTCCAGAT
CAAATTTTCTCCGGTGGCTAAAAAGTTGTTTGTGGTAACTGCAGTGAGTGCTATATCTGTAATTTTTCTGGCTCATCACTTTAAAAGAAA
ACGTGGAAAGAAGAAAGGAAAAATATTACCATGGGAACCAGAGCACCTCATACTTGAATACACTAAAAGAGCAGCATCAGACAAAGGTTC
AAGTTGTTCCAGTAGCAGACAGAATTTGACATTATCTTTAAGTTCTACCAAAGACAAAGGATCTCAAGTTTGTAACTATGCTAATGGAGG
ACTTTTCAGTAAATATTCAGGTTCTGCACAGAGTTTGGCCTCTGTCCAGAGTGTCAATTCTTGTCATAGCTGCGCTTGTGGCAATTCTAA
TTCCTGGGACAAAGCAGATGAAGATGATATTAAACTTGTTAATATTCCTGTGACTACTCCAGAGAACTTATACTTAATGGGTATGGAATT
GTTTGAAGAGGCATTGCGTCGATGGGAACAAGCTCTGACCTTTCGCAATAGACAGGCTGAAGATGAAGCCTGTGGTTCCATTAAACTGGG
TGCAGGAGATGCCATTGCTGAAGAAAATGTAGATGATATTATTAGTACTGAATTTATCCATAAACTCGAAGCTCTGCTGCAAAGAGCCTA
TCGTCTCCAAGAGGAGTTTGAAGCTACCCTTGGGGCATCTGATCCTAATTCCCTTGCTGATGATATTGATAAAGATACAGATATCACCAT
GAAGGGTAATGTGGAAGACTTTGGCCTGCGAGACACCTTGAGCATCGCATCCACGGATTCCTTTGCTTCCGCAGCAGAGCTTGCAGAACA
CAGAGAAGTACGGCATACCTACAGCCTGGAGTCCCTTTGTCACTGCCCATTTTACGAGGAAGCCATGCATTTAGTTGAAGAAGGAAAAAT
TTACTCCAGAGTACTGAGAACTGAAATGTTGGAGTGCCTAGGAGACAGTGATTTTCTTGCCAAACTTCACTGTATTCGACAGGCTTTTCA
GGTAATTCTTTCAGAATCAGCTAACAGGATATTCCTCGCTGAGAGCGGAAGGAAAATTTTATCAGCTTTAATTGTGAAAGCACGAAAGAA
TCCAAAGAAGTTTGAAGATGTTTTTGATGAAATGATCTATTTTTTAGAGCAGACCGATCACTGGGGTAGTACTGAAATGGAACTTGCTGC
TAGAGGGGTGAAAAATCTAAATTTTTATGATGTTGTTCTGGATTTTATATTAATGGACTCCTTTGAAGATTTGGAAAACCCACCCACATC
CATACAGAATGTAGTAAATAATCGATGGCTAAACTCATCCTTCAAAGAAACAGCTGTGGCTTCAAGTTGTTGGTCGGTGCTGAAACAGAA
AAGACAACAGATGAAGGTAACCTCTTTACTAAGAAGAGTTTTGCCTGAAGTAACCCCTAGTCGTCTGGCCAGCATCATAGGAGTGAAATC
CCTCCCCCCAGCAGATATCAGTGATATCATTCACTCAACAGAGAAAGGAGACTGGAATAAGCTGGGTATCTTGGACATGTTTCTAGGATG
CATTGCCAAAGCACTCACTGTACAGCTAAAAGCCAAAGGAACCACCATCACTGGAACAGCTGGTACCACTGTGGGCAAAGGAGTTACAAC
AGTTACTCTTCCGATGATTTTCAATTCCAGTTATCTCCGACGAGGTGAAAGTCATTGGTGGATGAAGGGCTCAACCCCTACCCAGATCTC
AGAGATCATCATTAAACTTATCAAGGATATGGCAGCAGGTCATCTGTCAGAAGCTTGGTCCCGAGTGACAAAAAATGCTATTGCAGAAAC
CATCATTGCCTTGACCAAGATGGAAGAAGAATTTAGGTCTCCAGTGAGATGTATTGCAACAACTAGACTCTGGCTTGCTCTCGCATCCCT
ATGTGTTCTTGATCAGGACCACGTAGATCGTCTCTCCTCGGGGAGATGGATGGGAAAGGATGGACAACAAAAACAAATGCCTATGTGTGA
TAACCATGATGATGGTGAAACTGCAGCAATCATTTTATGCAATGTCTGTGGAAATTTATGTACAGACTGTGACAGATTCCTTCACCTTCA
TCGAAGAACCAAAACTCATCAAAGACAGGTCTTCAAAGAAGAAGAAGAAGCTATAAAGGTTGACCTTCATGAAGGTTGTGGTAGAACCAA
ATTGTTCTGGTTGATGGCACTGGCAGATTCTAAAACAATGAAGGCAATGGTGGAATTCCGAGAACACACAGGCAAACCCACCACGAGTAG
CTCAGAAGCATGTCGCTTCTGTGGTTCCAGGAGTGGAACAGAGTTATCTGCTGTTGGCAGTGTTTGTTCTGATGCAGATTGCCAGGAATA
CGCTAAGATAGCCTGTAGTAAGACGCATCCTTGTGGCCATCCATGCGGGGGTGTTAAAAACGAAGAGCACTGTCTGCCCTGTCTACACGG
CTGTGACAAAAGTGCCACAAGCCTGAAGCAAGACGCCGATGACATGTGCATGATATGTTTCACCGAAGCGCTCTCGGCAGCACCAGCCAT
TCAGCTGGATTGTAGTCACATATTCCACTTACAGTGCTGTCGGCGAGTATTAGAAAATCGATGGCTTGGCCCAAGGATAACATTTGGATT
TATATCTTGTCCCATTTGCAAGAACAAAATTAATCACATAGTACTAAAAGACCTACTTGATCCAATAAAAGAACTCTATGAGGATGTCAG
AAGAAAAGCCTTAATGAGATTGGAATATGAAGGTCTGCATAAGAGTGAAGCTATCACAACTCCTGGTGTGAGGTTTTATAATGACCCAGC
TGGCTATGCAATGAATAGATATGCATATTATGTGTGCTACAAATGCAGAAAGGCATATTTTGGTGGTGAAGCTCGCTGCGATGCTGAGGC
TGGACGGGGAGATGATTATGATCCCAGAGAGCTCATTTGTGGTGCCTGTTCTGATGTTTCCAGGGCTCAGATGTGTCCCAAACATGGCAC
AGACTTTTTGGAATATAAATGTCGCTACTGCTGTTCAGTGGCTGTTTTTTTCTGTTTTGGAACAACACATTTTTGTAATGCTTGTCATGA
TGATTTTCAAAGAATGACTAGCATTCCTAAGGAAGAACTACCACACTGTCCTGCAGGTCCCAAAGGCAAGCAGTTAGAAGGAACTGAATG
TCCACTCCATGTTGTTCATCCACCCACTGGGGAAGAGTTTGCTCTGGGATGTGGAGTGTGCAGAAATGCCCACACTTTTTAGAACACGCA
GATCCTTTGTCTACAGAGAGAAAAATTGCCTTCATCCCCCAAGAGGATGCGGTGAAGTTTAAACTCTGCTCAGGATAAGGACGGGACCAT
TTTTACATCCATGAAAATGAACCATTCACAGTGCAAGAAGGATACCAAATACCATGTACATAATTCTTGCTATGAAAAGTTTCCCCATTA
TTTTGGTTTATCTTCTTTTGAACAAATGACATCAAACTTGTGAGGTGTTTGCATGTGGCCATTACCGTCATTGGCCTGTGAAGCATTGGA
CATTTATAGATAATTGATATAAAAGAATCGCCATGCCCATGGACTAAGAACGATGCTGGCTTTCAAGCAAAAAAGAAAAATAATCATTGT
TTATTGTATACTGCCTTTTTGTAATCCTGTACAATTGCATCACGGGTGGGGATAAAAAGAGGAATATTCTGGTTTATTTCCTAGACTGTT
ATTTAAAAAAAAAAAAAACATTGTGTTAGGACAGCATATAAATGTAATAAGTATCACACTGTATATAAACATATCAATGTTTGTCCTGTA
TAAGAATTACTAAATTACAAATGCAATTTCATTTAAACTTCTAGGTTAAGTTTGAGCCTGAAATTTTAATGAAGTGCAATACTGAGTGTG

>29189_29189_4_FAM73A-MYCBP2_FAM73A_chr1_78332076_ENST00000443751_MYCBP2_chr13_77641999_ENST00000357337_length(amino acids)=1104AA_BP=483
MSDCCSAPGISWEAGVGRPAVPGLELQIKFSPVAKKLFVVTAVSAISVIFLAHHFKRKRGKKKGKILPWEPEHLILEYTKRAASDKGSSC
SSSRQNLTLSLSSTKDKGSQVCNYANGGLFSKYSGSAQSLASVQSVNSCHSCACGNSNSWDKADEDDIKLVNIPVTTPENLYLMGMELFE
EALRRWEQALTFRNRQAEDEACGSIKLGAGDAIAEENVDDIISTEFIHKLEALLQRAYRLQEEFEATLGASDPNSLADDIDKDTDITMKG
NVEDFGLRDTLSIASTDSFASAAELAEHREVRHTYSLESLCHCPFYEEAMHLVEEGKIYSRVLRTEMLECLGDSDFLAKLHCIRQAFQVI
LSESANRIFLAESGRKILSALIVKARKNPKKFEDVFDEMIYFLEQTDHWGSTEMELAARGVKNLNFYDVVLDFILMDSFEDLENPPTSIQ
NVVNNRWLNSSFKETAVASSCWSVLKQKRQQMKVTSLLRRVLPEVTPSRLASIIGVKSLPPADISDIIHSTEKGDWNKLGILDMFLGCIA
KALTVQLKAKGTTITGTAGTTVGKGVTTVTLPMIFNSSYLRRGESHWWMKGSTPTQISEIIIKLIKDMAAGHLSEAWSRVTKNAIAETII
ALTKMEEEFRSPVRCIATTRLWLALASLCVLDQDHVDRLSSGRWMGKDGQQKQMPMCDNHDDGETAAIILCNVCGNLCTDCDRFLHLHRR
TKTHQRQVFKEEEEAIKVDLHEGCGRTKLFWLMALADSKTMKAMVEFREHTGKPTTSSSEACRFCGSRSGTELSAVGSVCSDADCQEYAK
IACSKTHPCGHPCGGVKNEEHCLPCLHGCDKSATSLKQDADDMCMICFTEALSAAPAIQLDCSHIFHLQCCRRVLENRWLGPRITFGFIS
CPICKNKINHIVLKDLLDPIKELYEDVRRKALMRLEYEGLHKSEAITTPGVRFYNDPAGYAMNRYAYYVCYKCRKAYFGGEARCDAEAGR
GDDYDPRELICGACSDVSRAQMCPKHGTDFLEYKCRYCCSVAVFFCFGTTHFCNACHDDFQRMTSIPKEELPHCPAGPKGKQLEGTECPL

--------------------------------------------------------------
>29189_29189_5_FAM73A-MYCBP2_FAM73A_chr1_78332076_ENST00000443751_MYCBP2_chr13_77641999_ENST00000407578_length(transcript)=4043nt_BP=1456nt
CTTCTCCATGTCAGACTGCTGCTCAGCGCCAGGCATCAGCTGGGAAGCTGGCGTGGGCAGGCCAGCTGTACCTGGCCTGGAGCTCCAGAT
CAAATTTTCTCCGGTGGCTAAAAAGTTGTTTGTGGTAACTGCAGTGAGTGCTATATCTGTAATTTTTCTGGCTCATCACTTTAAAAGAAA
ACGTGGAAAGAAGAAAGGAAAAATATTACCATGGGAACCAGAGCACCTCATACTTGAATACACTAAAAGAGCAGCATCAGACAAAGGTTC
AAGTTGTTCCAGTAGCAGACAGAATTTGACATTATCTTTAAGTTCTACCAAAGACAAAGGATCTCAAGTTTGTAACTATGCTAATGGAGG
ACTTTTCAGTAAATATTCAGGTTCTGCACAGAGTTTGGCCTCTGTCCAGAGTGTCAATTCTTGTCATAGCTGCGCTTGTGGCAATTCTAA
TTCCTGGGACAAAGCAGATGAAGATGATATTAAACTTGTTAATATTCCTGTGACTACTCCAGAGAACTTATACTTAATGGGTATGGAATT
GTTTGAAGAGGCATTGCGTCGATGGGAACAAGCTCTGACCTTTCGCAATAGACAGGCTGAAGATGAAGCCTGTGGTTCCATTAAACTGGG
TGCAGGAGATGCCATTGCTGAAGAAAATGTAGATGATATTATTAGTACTGAATTTATCCATAAACTCGAAGCTCTGCTGCAAAGAGCCTA
TCGTCTCCAAGAGGAGTTTGAAGCTACCCTTGGGGCATCTGATCCTAATTCCCTTGCTGATGATATTGATAAAGATACAGATATCACCAT
GAAGGGTAATGTGGAAGACTTTGGCCTGCGAGACACCTTGAGCATCGCATCCACGGATTCCTTTGCTTCCGCAGCAGAGCTTGCAGAACA
CAGAGAAGTACGGCATACCTACAGCCTGGAGTCCCTTTGTCACTGCCCATTTTACGAGGAAGCCATGCATTTAGTTGAAGAAGGAAAAAT
TTACTCCAGAGTACTGAGAACTGAAATGTTGGAGTGCCTAGGAGACAGTGATTTTCTTGCCAAACTTCACTGTATTCGACAGGCTTTTCA
GGTAATTCTTTCAGAATCAGCTAACAGGATATTCCTCGCTGAGAGCGGAAGGAAAATTTTATCAGCTTTAATTGTGAAAGCACGAAAGAA
TCCAAAGAAGTTTGAAGATGTTTTTGATGAAATGATCTATTTTTTAGAGCAGACCGATCACTGGGGTAGTACTGAAATGGAACTTGCTGC
TAGAGGGGTGAAAAATCTAAATTTTTATGATGTTGTTCTGGATTTTATATTAATGGACTCCTTTGAAGATTTGGAAAACCCACCCACATC
CATACAGAATGTAGTAAATAATCGATGGCTAAACTCATCCTTCAAAGAAACAGCTGTGGCTTCAAGTTGTTGGTCGGTGCTGAAACAGAA
AAGACAACAGATGAAGGTAACCTCTTTACTAAGAAGAGTTTTGCCTGAAGTAACCCCTAGTCGTCTGGCCAGCATCATAGGAGTGAAATC
CCTCCCCCCAGCAGATATCAGTGATATCATTCACTCAACAGAGAAAGGAGACTGGAATAAGCTGGGTATCTTGGACATGTTTCTAGGATG
CATTGCCAAAGCACTCACTGTACAGCTAAAAGCCAAAGGAACCACCATCACTGGAACAGCTGGTACCACTGTGGGCAAAGGAGTTACAAC
AGTTACTCTTCCGATGATTTTCAATTCCAGTTATCTCCGACGAGGTGAAAGTCATTGGTGGATGAAGGGCTCAACCCCTACCCAGATCTC
AGAGATCATCATTAAACTTATCAAGGATATGGCAGCAGGTCATCTGTCAGAAGCTTGGTCCCGAGTGACAAAAAATGCTATTGCAGAAAC
CATCATTGCCTTGACCAAGATGGAAGAAGAATTTAGGTCTCCAGTGAGATGTATTGCAACAACTAGACTCTGGCTTGCTCTCGCATCCCT
ATGTGTTCTTGATCAGGACCACGTAGATCGTCTCTCCTCGGGGAGATGGATGGGAAAGGATGGACAACAAAAACAAATGCCTATGTGTGA
TAACCATGATGATGGTGAAACTGCAGCAATCATTTTATGCAATGTCTGTGGAAATTTATGTACAGACTGTGACAGATTCCTTCACCTTCA
TCGAAGAACCAAAACTCATCAAAGACAGGTCTTCAAAGAAGAAGAAGAAGCTATAAAGGTTGACCTTCATGAAGGTTGTGGTAGAACCAA
ATTGTTCTGGTTGATGGCACTGGCAGATTCTAAAACAATGAAGGCAATGGTGGAATTCCGAGAACACACAGGCAAACCCACCACGAGTAG
CTCAGAAGCATGTCGCTTCTGTGGTTCCAGGAGTGGAACAGAGTTATCTGCTGTTGGCAGTGTTTGTTCTGATGCAGATTGCCAGGAATA
CGCTAAGATAGCCTGTAGTAAGACGCATCCTTGTGGCCATCCATGCGGGGGTGTTAAAAACGAAGAGCACTGTCTGCCCTGTCTACACGG
CTGTGACAAAAGTGCCACAAGCCTGAAGCAAGACGCCGATGACATGTGCATGATATGTTTCACCGAAGCGCTCTCGGCAGCACCAGCCAT
TCAGCTGGATTGTAGTCACATATTCCACTTACAGTGCTGTCGGCGAGTATTAGAAAATCGATGGCTTGGCCCAAGGATAACATTTGGATT
TATATCTTGTCCCATTTGCAAGAACAAAATTAATCACATAGTACTAAAAGACCTACTTGATCCAATAAAAGAACTCTATGAGGATGTCAG
AAGAAAAGCCTTAATGAGATTGGAATATGAAGGTCTGCATAAGAGTGAAGCTATCACAACTCCTGGTGTGAGGTTTTATAATGACCCAGC
TGGCTATGCAATGAATAGATATGCATATTATGTGTGCTACAAATGCAGAAAGGCATATTTTGGTGGTGAAGCTCGCTGCGATGCTGAGGC
TGGACGGGGAGATGATTATGATCCCAGAGAGCTCATTTGTGGTGCCTGTTCTGATGTTTCCAGGGCTCAGATGTGTCCCAAACATGGCAC
AGACTTTTTGGAATATAAATGTCGCTACTGCTGTTCAGTGGCTGTTTTTTTCTGTTTTGGAACAACACATTTTTGTAATGCTTGTCATGA
TGATTTTCAAAGAATGACTAGCATTCCTAAGGAAGAACTACCACACTGTCCTGCAGGTCCCAAAGGCAAGCAGTTAGAAGGAACTGAATG
TCCACTCCATGTTGTTCATCCACCCACTGGGGAAGAGTTTGCTCTGGGATGTGGAGTGTGCAGAAATGCCCACACTTTTTAGAACACGCA
GATCCTTTGTCTACAGAGAGAAAAATTGCCTTCATCCCCCAAGAGGATGCGGTGAAGTTTAAACTCTGCTCAGGATAAGGACGGGACCAT
TTTTACATCCATGAAAATGAACCATTCACAGTGCAAGAAGGATACCAAATACCATGTACATAATTCTTGCTATGAAAAGTTTCCCCATTA
TTTTGGTTTATCTTCTTTTGAACAAATGACATCAAACTTGTGAGGTGTTTGCATGTGGCCATTACCGTCATTGGCCTGTGAAGCATTGGA
CATTTATAGATAATTGATATAAAAGAATCGCCATGCCCATGGACTAAGAACGATGCTGGCTTTCAAGCAAAAAAGAAAAATAATCATTGT
TTATTGTATACTGCCTTTTTGTAATCCTGTACAATTGCATCACGGGTGGGGATAAAAAGAGGAATATTCTGGTTTATTTCCTAGACTGTT
ATTTAAAAAAAAAAAAAACATTGTGTTAGGACAGCATATAAATGTAATAAGTATCACACTGTATATAAACATATCAATGTTTGTCCTGTA
TAAGAATTACTAAATTACAAATGCAATTTCATTTAAACTTCTAGGTTAAGTTTGAGCCTGAAATTTTAATGAAGTGCAATACTGAGTGTG

>29189_29189_5_FAM73A-MYCBP2_FAM73A_chr1_78332076_ENST00000443751_MYCBP2_chr13_77641999_ENST00000407578_length(amino acids)=1104AA_BP=483
MSDCCSAPGISWEAGVGRPAVPGLELQIKFSPVAKKLFVVTAVSAISVIFLAHHFKRKRGKKKGKILPWEPEHLILEYTKRAASDKGSSC
SSSRQNLTLSLSSTKDKGSQVCNYANGGLFSKYSGSAQSLASVQSVNSCHSCACGNSNSWDKADEDDIKLVNIPVTTPENLYLMGMELFE
EALRRWEQALTFRNRQAEDEACGSIKLGAGDAIAEENVDDIISTEFIHKLEALLQRAYRLQEEFEATLGASDPNSLADDIDKDTDITMKG
NVEDFGLRDTLSIASTDSFASAAELAEHREVRHTYSLESLCHCPFYEEAMHLVEEGKIYSRVLRTEMLECLGDSDFLAKLHCIRQAFQVI
LSESANRIFLAESGRKILSALIVKARKNPKKFEDVFDEMIYFLEQTDHWGSTEMELAARGVKNLNFYDVVLDFILMDSFEDLENPPTSIQ
NVVNNRWLNSSFKETAVASSCWSVLKQKRQQMKVTSLLRRVLPEVTPSRLASIIGVKSLPPADISDIIHSTEKGDWNKLGILDMFLGCIA
KALTVQLKAKGTTITGTAGTTVGKGVTTVTLPMIFNSSYLRRGESHWWMKGSTPTQISEIIIKLIKDMAAGHLSEAWSRVTKNAIAETII
ALTKMEEEFRSPVRCIATTRLWLALASLCVLDQDHVDRLSSGRWMGKDGQQKQMPMCDNHDDGETAAIILCNVCGNLCTDCDRFLHLHRR
TKTHQRQVFKEEEEAIKVDLHEGCGRTKLFWLMALADSKTMKAMVEFREHTGKPTTSSSEACRFCGSRSGTELSAVGSVCSDADCQEYAK
IACSKTHPCGHPCGGVKNEEHCLPCLHGCDKSATSLKQDADDMCMICFTEALSAAPAIQLDCSHIFHLQCCRRVLENRWLGPRITFGFIS
CPICKNKINHIVLKDLLDPIKELYEDVRRKALMRLEYEGLHKSEAITTPGVRFYNDPAGYAMNRYAYYVCYKCRKAYFGGEARCDAEAGR
GDDYDPRELICGACSDVSRAQMCPKHGTDFLEYKCRYCCSVAVFFCFGTTHFCNACHDDFQRMTSIPKEELPHCPAGPKGKQLEGTECPL

--------------------------------------------------------------
>29189_29189_6_FAM73A-MYCBP2_FAM73A_chr1_78332076_ENST00000443751_MYCBP2_chr13_77641999_ENST00000544440_length(transcript)=4043nt_BP=1456nt
CTTCTCCATGTCAGACTGCTGCTCAGCGCCAGGCATCAGCTGGGAAGCTGGCGTGGGCAGGCCAGCTGTACCTGGCCTGGAGCTCCAGAT
CAAATTTTCTCCGGTGGCTAAAAAGTTGTTTGTGGTAACTGCAGTGAGTGCTATATCTGTAATTTTTCTGGCTCATCACTTTAAAAGAAA
ACGTGGAAAGAAGAAAGGAAAAATATTACCATGGGAACCAGAGCACCTCATACTTGAATACACTAAAAGAGCAGCATCAGACAAAGGTTC
AAGTTGTTCCAGTAGCAGACAGAATTTGACATTATCTTTAAGTTCTACCAAAGACAAAGGATCTCAAGTTTGTAACTATGCTAATGGAGG
ACTTTTCAGTAAATATTCAGGTTCTGCACAGAGTTTGGCCTCTGTCCAGAGTGTCAATTCTTGTCATAGCTGCGCTTGTGGCAATTCTAA
TTCCTGGGACAAAGCAGATGAAGATGATATTAAACTTGTTAATATTCCTGTGACTACTCCAGAGAACTTATACTTAATGGGTATGGAATT
GTTTGAAGAGGCATTGCGTCGATGGGAACAAGCTCTGACCTTTCGCAATAGACAGGCTGAAGATGAAGCCTGTGGTTCCATTAAACTGGG
TGCAGGAGATGCCATTGCTGAAGAAAATGTAGATGATATTATTAGTACTGAATTTATCCATAAACTCGAAGCTCTGCTGCAAAGAGCCTA
TCGTCTCCAAGAGGAGTTTGAAGCTACCCTTGGGGCATCTGATCCTAATTCCCTTGCTGATGATATTGATAAAGATACAGATATCACCAT
GAAGGGTAATGTGGAAGACTTTGGCCTGCGAGACACCTTGAGCATCGCATCCACGGATTCCTTTGCTTCCGCAGCAGAGCTTGCAGAACA
CAGAGAAGTACGGCATACCTACAGCCTGGAGTCCCTTTGTCACTGCCCATTTTACGAGGAAGCCATGCATTTAGTTGAAGAAGGAAAAAT
TTACTCCAGAGTACTGAGAACTGAAATGTTGGAGTGCCTAGGAGACAGTGATTTTCTTGCCAAACTTCACTGTATTCGACAGGCTTTTCA
GGTAATTCTTTCAGAATCAGCTAACAGGATATTCCTCGCTGAGAGCGGAAGGAAAATTTTATCAGCTTTAATTGTGAAAGCACGAAAGAA
TCCAAAGAAGTTTGAAGATGTTTTTGATGAAATGATCTATTTTTTAGAGCAGACCGATCACTGGGGTAGTACTGAAATGGAACTTGCTGC
TAGAGGGGTGAAAAATCTAAATTTTTATGATGTTGTTCTGGATTTTATATTAATGGACTCCTTTGAAGATTTGGAAAACCCACCCACATC
CATACAGAATGTAGTAAATAATCGATGGCTAAACTCATCCTTCAAAGAAACAGCTGTGGCTTCAAGTTGTTGGTCGGTGCTGAAACAGAA
AAGACAACAGATGAAGGTAACCTCTTTACTAAGAAGAGTTTTGCCTGAAGTAACCCCTAGTCGTCTGGCCAGCATCATAGGAGTGAAATC
CCTCCCCCCAGCAGATATCAGTGATATCATTCACTCAACAGAGAAAGGAGACTGGAATAAGCTGGGTATCTTGGACATGTTTCTAGGATG
CATTGCCAAAGCACTCACTGTACAGCTAAAAGCCAAAGGAACCACCATCACTGGAACAGCTGGTACCACTGTGGGCAAAGGAGTTACAAC
AGTTACTCTTCCGATGATTTTCAATTCCAGTTATCTCCGACGAGGTGAAAGTCATTGGTGGATGAAGGGCTCAACCCCTACCCAGATCTC
AGAGATCATCATTAAACTTATCAAGGATATGGCAGCAGGTCATCTGTCAGAAGCTTGGTCCCGAGTGACAAAAAATGCTATTGCAGAAAC
CATCATTGCCTTGACCAAGATGGAAGAAGAATTTAGGTCTCCAGTGAGATGTATTGCAACAACTAGACTCTGGCTTGCTCTCGCATCCCT
ATGTGTTCTTGATCAGGACCACGTAGATCGTCTCTCCTCGGGGAGATGGATGGGAAAGGATGGACAACAAAAACAAATGCCTATGTGTGA
TAACCATGATGATGGTGAAACTGCAGCAATCATTTTATGCAATGTCTGTGGAAATTTATGTACAGACTGTGACAGATTCCTTCACCTTCA
TCGAAGAACCAAAACTCATCAAAGACAGGTCTTCAAAGAAGAAGAAGAAGCTATAAAGGTTGACCTTCATGAAGGTTGTGGTAGAACCAA
ATTGTTCTGGTTGATGGCACTGGCAGATTCTAAAACAATGAAGGCAATGGTGGAATTCCGAGAACACACAGGCAAACCCACCACGAGTAG
CTCAGAAGCATGTCGCTTCTGTGGTTCCAGGAGTGGAACAGAGTTATCTGCTGTTGGCAGTGTTTGTTCTGATGCAGATTGCCAGGAATA
CGCTAAGATAGCCTGTAGTAAGACGCATCCTTGTGGCCATCCATGCGGGGGTGTTAAAAACGAAGAGCACTGTCTGCCCTGTCTACACGG
CTGTGACAAAAGTGCCACAAGCCTGAAGCAAGACGCCGATGACATGTGCATGATATGTTTCACCGAAGCGCTCTCGGCAGCACCAGCCAT
TCAGCTGGATTGTAGTCACATATTCCACTTACAGTGCTGTCGGCGAGTATTAGAAAATCGATGGCTTGGCCCAAGGATAACATTTGGATT
TATATCTTGTCCCATTTGCAAGAACAAAATTAATCACATAGTACTAAAAGACCTACTTGATCCAATAAAAGAACTCTATGAGGATGTCAG
AAGAAAAGCCTTAATGAGATTGGAATATGAAGGTCTGCATAAGAGTGAAGCTATCACAACTCCTGGTGTGAGGTTTTATAATGACCCAGC
TGGCTATGCAATGAATAGATATGCATATTATGTGTGCTACAAATGCAGAAAGGCATATTTTGGTGGTGAAGCTCGCTGCGATGCTGAGGC
TGGACGGGGAGATGATTATGATCCCAGAGAGCTCATTTGTGGTGCCTGTTCTGATGTTTCCAGGGCTCAGATGTGTCCCAAACATGGCAC
AGACTTTTTGGAATATAAATGTCGCTACTGCTGTTCAGTGGCTGTTTTTTTCTGTTTTGGAACAACACATTTTTGTAATGCTTGTCATGA
TGATTTTCAAAGAATGACTAGCATTCCTAAGGAAGAACTACCACACTGTCCTGCAGGTCCCAAAGGCAAGCAGTTAGAAGGAACTGAATG
TCCACTCCATGTTGTTCATCCACCCACTGGGGAAGAGTTTGCTCTGGGATGTGGAGTGTGCAGAAATGCCCACACTTTTTAGAACACGCA
GATCCTTTGTCTACAGAGAGAAAAATTGCCTTCATCCCCCAAGAGGATGCGGTGAAGTTTAAACTCTGCTCAGGATAAGGACGGGACCAT
TTTTACATCCATGAAAATGAACCATTCACAGTGCAAGAAGGATACCAAATACCATGTACATAATTCTTGCTATGAAAAGTTTCCCCATTA
TTTTGGTTTATCTTCTTTTGAACAAATGACATCAAACTTGTGAGGTGTTTGCATGTGGCCATTACCGTCATTGGCCTGTGAAGCATTGGA
CATTTATAGATAATTGATATAAAAGAATCGCCATGCCCATGGACTAAGAACGATGCTGGCTTTCAAGCAAAAAAGAAAAATAATCATTGT
TTATTGTATACTGCCTTTTTGTAATCCTGTACAATTGCATCACGGGTGGGGATAAAAAGAGGAATATTCTGGTTTATTTCCTAGACTGTT
ATTTAAAAAAAAAAAAAACATTGTGTTAGGACAGCATATAAATGTAATAAGTATCACACTGTATATAAACATATCAATGTTTGTCCTGTA
TAAGAATTACTAAATTACAAATGCAATTTCATTTAAACTTCTAGGTTAAGTTTGAGCCTGAAATTTTAATGAAGTGCAATACTGAGTGTG

>29189_29189_6_FAM73A-MYCBP2_FAM73A_chr1_78332076_ENST00000443751_MYCBP2_chr13_77641999_ENST00000544440_length(amino acids)=1104AA_BP=483
MSDCCSAPGISWEAGVGRPAVPGLELQIKFSPVAKKLFVVTAVSAISVIFLAHHFKRKRGKKKGKILPWEPEHLILEYTKRAASDKGSSC
SSSRQNLTLSLSSTKDKGSQVCNYANGGLFSKYSGSAQSLASVQSVNSCHSCACGNSNSWDKADEDDIKLVNIPVTTPENLYLMGMELFE
EALRRWEQALTFRNRQAEDEACGSIKLGAGDAIAEENVDDIISTEFIHKLEALLQRAYRLQEEFEATLGASDPNSLADDIDKDTDITMKG
NVEDFGLRDTLSIASTDSFASAAELAEHREVRHTYSLESLCHCPFYEEAMHLVEEGKIYSRVLRTEMLECLGDSDFLAKLHCIRQAFQVI
LSESANRIFLAESGRKILSALIVKARKNPKKFEDVFDEMIYFLEQTDHWGSTEMELAARGVKNLNFYDVVLDFILMDSFEDLENPPTSIQ
NVVNNRWLNSSFKETAVASSCWSVLKQKRQQMKVTSLLRRVLPEVTPSRLASIIGVKSLPPADISDIIHSTEKGDWNKLGILDMFLGCIA
KALTVQLKAKGTTITGTAGTTVGKGVTTVTLPMIFNSSYLRRGESHWWMKGSTPTQISEIIIKLIKDMAAGHLSEAWSRVTKNAIAETII
ALTKMEEEFRSPVRCIATTRLWLALASLCVLDQDHVDRLSSGRWMGKDGQQKQMPMCDNHDDGETAAIILCNVCGNLCTDCDRFLHLHRR
TKTHQRQVFKEEEEAIKVDLHEGCGRTKLFWLMALADSKTMKAMVEFREHTGKPTTSSSEACRFCGSRSGTELSAVGSVCSDADCQEYAK
IACSKTHPCGHPCGGVKNEEHCLPCLHGCDKSATSLKQDADDMCMICFTEALSAAPAIQLDCSHIFHLQCCRRVLENRWLGPRITFGFIS
CPICKNKINHIVLKDLLDPIKELYEDVRRKALMRLEYEGLHKSEAITTPGVRFYNDPAGYAMNRYAYYVCYKCRKAYFGGEARCDAEAGR
GDDYDPRELICGACSDVSRAQMCPKHGTDFLEYKCRYCCSVAVFFCFGTTHFCNACHDDFQRMTSIPKEELPHCPAGPKGKQLEGTECPL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FAM73A-MYCBP2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FAM73A-MYCBP2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FAM73A-MYCBP2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource