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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:AFF3-SAP130 (FusionGDB2 ID:HG3899TG79595) |
Fusion Gene Summary for AFF3-SAP130 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: AFF3-SAP130 | Fusion gene ID: hg3899tg79595 | Hgene | Tgene | Gene symbol | AFF3 | SAP130 | Gene ID | 3899 | 79595 |
| Gene name | AF4/FMR2 family member 3 | Sin3A associated protein 130 | |
| Synonyms | LAF4|MLLT2-like | - | |
| Cytomap | ('AFF3')('SAP130') 2q11.2 | 2q14.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | AF4/FMR2 family member 3MLLT2-related proteinlymphoid nuclear protein 4lymphoid nuclear protein related to AF4protein LAF-4 | histone deacetylase complex subunit SAP130130 kDa Sin3-associated polypeptideSin3-associated polypeptide p130Sin3A associated protein 130kDa | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | P51826 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000409236, ENST00000317233, ENST00000356421, ENST00000409579, ENST00000483600, | ||
| Fusion gene scores | * DoF score | 17 X 13 X 7=1547 | 8 X 6 X 4=192 |
| # samples | 17 | 8 | |
| ** MAII score | log2(17/1547*10)=-3.18586654531133 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/192*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: AFF3 [Title/Abstract] AND SAP130 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | AFF3(100720862)-SAP130(128770729), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | AFF3-SAP130 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. AFF3-SAP130 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. AFF3-SAP130 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. AFF3-SAP130 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. AFF3-SAP130 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF. AFF3-SAP130 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. AFF3-SAP130 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF. AFF3-SAP130 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across AFF3 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across SAP130 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
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Fusion Gene ORF analysis for AFF3-SAP130 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000356421 | ENST00000357702 | AFF3 | chr2 | 100720862 | - | SAP130 | chr2 | 128770729 | - | 0.004829479 | 0.99517053 |
| ENST00000356421 | ENST00000259235 | AFF3 | chr2 | 100720862 | - | SAP130 | chr2 | 128770729 | - | 0.005492996 | 0.994507 |
| ENST00000356421 | ENST00000259234 | AFF3 | chr2 | 100720862 | - | SAP130 | chr2 | 128770729 | - | 0.004899032 | 0.99510103 |
| ENST00000317233 | ENST00000357702 | AFF3 | chr2 | 100720862 | - | SAP130 | chr2 | 128770729 | - | 0.005388517 | 0.9946115 |
| ENST00000317233 | ENST00000259235 | AFF3 | chr2 | 100720862 | - | SAP130 | chr2 | 128770729 | - | 0.006079533 | 0.99392045 |
| ENST00000317233 | ENST00000259234 | AFF3 | chr2 | 100720862 | - | SAP130 | chr2 | 128770729 | - | 0.005512273 | 0.9944877 |
| ENST00000409579 | ENST00000357702 | AFF3 | chr2 | 100720862 | - | SAP130 | chr2 | 128770729 | - | 0.004708517 | 0.9952915 |
| ENST00000409579 | ENST00000259235 | AFF3 | chr2 | 100720862 | - | SAP130 | chr2 | 128770729 | - | 0.005271208 | 0.99472886 |
| ENST00000409579 | ENST00000259234 | AFF3 | chr2 | 100720862 | - | SAP130 | chr2 | 128770729 | - | 0.00481664 | 0.9951834 |
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Fusion Genomic Features for AFF3-SAP130 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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Fusion Protein Features for AFF3-SAP130 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:100720862/chr2:128770729) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| AFF3 | . |
| FUNCTION: Putative transcription activator that may function in lymphoid development and oncogenesis. Binds, in vitro, to double-stranded DNA. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | SAP130 | chr2:100720862 | chr2:128770729 | ENST00000259235 | 4 | 20 | 234_238 | 232 | 1049.0 | Compositional bias | Note=Poly-Ala | |
| Tgene | SAP130 | chr2:100720862 | chr2:128770729 | ENST00000259235 | 4 | 20 | 709_836 | 232 | 1049.0 | Compositional bias | Note=Pro-rich | |
| Tgene | SAP130 | chr2:100720862 | chr2:128770729 | ENST00000357702 | 4 | 21 | 234_238 | 232 | 1084.0 | Compositional bias | Note=Poly-Ala | |
| Tgene | SAP130 | chr2:100720862 | chr2:128770729 | ENST00000357702 | 4 | 21 | 709_836 | 232 | 1084.0 | Compositional bias | Note=Pro-rich |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | AFF3 | chr2:100720862 | chr2:128770729 | ENST00000317233 | - | 3 | 24 | 413_419 | 17 | 1227.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF3 | chr2:100720862 | chr2:128770729 | ENST00000317233 | - | 3 | 24 | 422_432 | 17 | 1227.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF3 | chr2:100720862 | chr2:128770729 | ENST00000317233 | - | 3 | 24 | 440_445 | 17 | 1227.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF3 | chr2:100720862 | chr2:128770729 | ENST00000317233 | - | 3 | 24 | 670_679 | 17 | 1227.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF3 | chr2:100720862 | chr2:128770729 | ENST00000356421 | - | 2 | 24 | 413_419 | 17 | 1252.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF3 | chr2:100720862 | chr2:128770729 | ENST00000356421 | - | 2 | 24 | 422_432 | 17 | 1252.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF3 | chr2:100720862 | chr2:128770729 | ENST00000356421 | - | 2 | 24 | 440_445 | 17 | 1252.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF3 | chr2:100720862 | chr2:128770729 | ENST00000356421 | - | 2 | 24 | 670_679 | 17 | 1252.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF3 | chr2:100720862 | chr2:128770729 | ENST00000409236 | - | 2 | 23 | 413_419 | 17 | 1227.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF3 | chr2:100720862 | chr2:128770729 | ENST00000409236 | - | 2 | 23 | 422_432 | 17 | 1227.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF3 | chr2:100720862 | chr2:128770729 | ENST00000409236 | - | 2 | 23 | 440_445 | 17 | 1227.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF3 | chr2:100720862 | chr2:128770729 | ENST00000409236 | - | 2 | 23 | 670_679 | 17 | 1227.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF3 | chr2:100720862 | chr2:128770729 | ENST00000409579 | - | 3 | 25 | 413_419 | 17 | 1252.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF3 | chr2:100720862 | chr2:128770729 | ENST00000409579 | - | 3 | 25 | 422_432 | 17 | 1252.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF3 | chr2:100720862 | chr2:128770729 | ENST00000409579 | - | 3 | 25 | 440_445 | 17 | 1252.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF3 | chr2:100720862 | chr2:128770729 | ENST00000409579 | - | 3 | 25 | 670_679 | 17 | 1252.0 | Compositional bias | Note=Poly-Ser |
| Tgene | SAP130 | chr2:100720862 | chr2:128770729 | ENST00000259235 | 4 | 20 | 124_169 | 232 | 1049.0 | Compositional bias | Note=Pro-rich | |
| Tgene | SAP130 | chr2:100720862 | chr2:128770729 | ENST00000259235 | 4 | 20 | 81_85 | 232 | 1049.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | SAP130 | chr2:100720862 | chr2:128770729 | ENST00000357702 | 4 | 21 | 124_169 | 232 | 1084.0 | Compositional bias | Note=Pro-rich | |
| Tgene | SAP130 | chr2:100720862 | chr2:128770729 | ENST00000357702 | 4 | 21 | 81_85 | 232 | 1084.0 | Compositional bias | Note=Poly-Ser |
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Fusion Gene Sequence for AFF3-SAP130 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >2693_2693_1_AFF3-SAP130_AFF3_chr2_100720862_ENST00000317233_SAP130_chr2_128770729_ENST00000259234_length(transcript)=3623nt_BP=289nt CGCCAGCGAGAAGAGAGCTCCACGCTCAGCCTCAGAAGAAAGACGTTCAACGACTTACTGGGGAGAGAAAGAAAAGGAACGGGAGCTGAG AGCTGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGG CGGCCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAAT GGGACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCA AATGCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCT CCTGCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGT AGGCCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACA CTACCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCT GCAGCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGT ACCATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAG CAGATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCC AATCCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCA TACCCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCT GCCATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGA CATATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTT GGCACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGA AAGACTTCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACCGTG GTGCAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCCACA GATGGAATGGCAGTTCGGAAAACCCTCATTCCTCCTCAGCCTCCTGATGTTGCTAGTCCTCGAGTGGAAAGCTCTATGCGGAGTACGTCT GGGTCACCTAGGCCTGCAGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTATCC AATCAAAATAATGATCAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCCAGT CCCCCGTCACAACCAGCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCACCT CCATCAGTCACTGTGGGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATGGAT ATCATGAGGCCAGTTTCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATGCCT ACAAGTGACCTACCACCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATGGAG ACAAACAGCACTGATGATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATTGAT GAGGAAGGTGTGAGATATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTACCAC CACTTTCAGAGGTACAGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGTCGT GCTCAAGGCTGGAAAGTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAACCTG CAGGAAGGGATTATCCCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGGTGT AAACTTGTGATGGATCAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAACAAG AACGGGACTGTCAAAAAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATGAAG AATGATGGTGGGGGTGGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAAAGC AGAGGAACCCATGACATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTGTTA AACCTGATCTGTGTCATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCAGCC TTCCGGTTTATAGACTGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGTTAT CTCTCTACACTGAAAATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAGCAG TGCCACGGCACCAAGCGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCCCAA GTGAAATTGTTATATCGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCAGAT CCTTGTTCTGAAGTACATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGTTAA TAAAGGACTCAAAGAGGTTTTTG >2693_2693_1_AFF3-SAP130_AFF3_chr2_100720862_ENST00000317233_SAP130_chr2_128770729_ENST00000259234_length(amino acids)=843AA_BP= MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT QGLQPAPMGTQQPQPEGKTSVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQ PPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKK PRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDS MLKVLDHKDRVLKLLNKNGTVKKVSKLKRKEKV -------------------------------------------------------------- >2693_2693_2_AFF3-SAP130_AFF3_chr2_100720862_ENST00000317233_SAP130_chr2_128770729_ENST00000259235_length(transcript)=3527nt_BP=289nt CGCCAGCGAGAAGAGAGCTCCACGCTCAGCCTCAGAAGAAAGACGTTCAACGACTTACTGGGGAGAGAAAGAAAAGGAACGGGAGCTGAG AGCTGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGG CGGCCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAAT GGGACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCA AATGCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCT CCTGCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGT AGGCCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACA CTACCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCT GCAGCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGT ACCATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAG CAGATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCC AATCCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCA TACCCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCT GCCATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGA CATATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTT GGCACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGA AAGACTTCAGCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACC GTGGTGCAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCC ACAGATGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTATCCAATCAAAATAAT GATCAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCCAGTCCCCCGTCACAA CCAGCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCACCTCCATCAGTCACT GTGGGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATGGATATCATGAGGCCA GTTTCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATGCCTACAAGTGACCTA CCACCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATGGAGACAAACAGCACT GATGATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATTGATGAGGAAGGTGTG AGATATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTACCACCACTTTCAGAGG TACAGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGTCGTGCTCAAGGCTGG AAAGTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAACCTGCAGGAAGGGATT ATCCCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGGTGTAAACTTGTGATG GATCAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAACAAGAACGGGACTGTC AAAAAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATGAAGAATGATGGTGGG GGTGGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAAAGCAGAGGAACCCAT GACATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTGTTAAACCTGATCTGT GTCATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCAGCCTTCCGGTTTATA GACTGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGTTATCTCTCTACACTG AAAATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAGCAGTGCCACGGCACC AAGCGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCCCAAGTGAAATTGTTA TATCGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCAGATCCTTGTTCTGAA GTACATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGTTAATAAAGGACTCAA AGAGGTTTTTGTACTTG >2693_2693_2_AFF3-SAP130_AFF3_chr2_100720862_ENST00000317233_SAP130_chr2_128770729_ENST00000259235_length(amino acids)=809AA_BP= MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT QGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVS MATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPV PEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVK AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLT NLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRKEKV -------------------------------------------------------------- >2693_2693_3_AFF3-SAP130_AFF3_chr2_100720862_ENST00000317233_SAP130_chr2_128770729_ENST00000357702_length(transcript)=3633nt_BP=289nt CGCCAGCGAGAAGAGAGCTCCACGCTCAGCCTCAGAAGAAAGACGTTCAACGACTTACTGGGGAGAGAAAGAAAAGGAACGGGAGCTGAG AGCTGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGG CGGCCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAAT GGGACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCA AATGCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCT CCTGCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGT AGGCCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACA CTACCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCT GCAGCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGT ACCATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAG CAGATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCC AATCCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCA TACCCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCT GCCATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGA CATATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTT GGCACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGA AAGACTTCAGCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACC GTGGTGCAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCC ACAGATGGAATGGCAGTTCGGAAAACCCTCATTCCTCCTCAGCCTCCTGATGTTGCTAGTCCTCGAGTGGAAAGCTCTATGCGGAGTACG TCTGGGTCACCTAGGCCTGCAGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTA TCCAATCAAAATAATGATCAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCC AGTCCCCCGTCACAACCAGCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCA CCTCCATCAGTCACTGTGGGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATG GATATCATGAGGCCAGTTTCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATG CCTACAAGTGACCTACCACCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATG GAGACAAACAGCACTGATGATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATT GATGAGGAAGGTGTGAGATATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTAC CACCACTTTCAGAGGTACAGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGT CGTGCTCAAGGCTGGAAAGTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAAC CTGCAGGAAGGGATTATCCCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGG TGTAAACTTGTGATGGATCAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAAC AAGAACGGGACTGTCAAAAAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATG AAGAATGATGGTGGGGGTGGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAA AGCAGAGGAACCCATGACATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTG TTAAACCTGATCTGTGTCATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCA GCCTTCCGGTTTATAGACTGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGT TATCTCTCTACACTGAAAATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAG CAGTGCCACGGCACCAAGCGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCC CAAGTGAAATTGTTATATCGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCA GATCCTTGTTCTGAAGTACATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGT TAATAAAGGACTCAAAGAGGTTTTTGTACTTGC >2693_2693_3_AFF3-SAP130_AFF3_chr2_100720862_ENST00000317233_SAP130_chr2_128770729_ENST00000357702_length(amino acids)=844AA_BP= MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT QGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPP QPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTI PGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRK KPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKE EKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARD SMLKVLDHKDRVLKLLNKNGTVKKVSKLKRKEKV -------------------------------------------------------------- >2693_2693_4_AFF3-SAP130_AFF3_chr2_100720862_ENST00000356421_SAP130_chr2_128770729_ENST00000259234_length(transcript)=3531nt_BP=197nt CTGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGGCG GCCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAATGG GACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCAAA TGCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCTCC TGCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGTAG GCCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACACT ACCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCTGC AGCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGTAC CATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAGCA GATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCCAA TCCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCATA CCCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCTGC CATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGACA TATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTTGG CACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGAAA GACTTCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACCGTGGT GCAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCCACAGA TGGAATGGCAGTTCGGAAAACCCTCATTCCTCCTCAGCCTCCTGATGTTGCTAGTCCTCGAGTGGAAAGCTCTATGCGGAGTACGTCTGG GTCACCTAGGCCTGCAGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTATCCAA TCAAAATAATGATCAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCCAGTCC CCCGTCACAACCAGCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCACCTCC ATCAGTCACTGTGGGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATGGATAT CATGAGGCCAGTTTCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATGCCTAC AAGTGACCTACCACCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATGGAGAC AAACAGCACTGATGATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATTGATGA GGAAGGTGTGAGATATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTACCACCA CTTTCAGAGGTACAGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGTCGTGC TCAAGGCTGGAAAGTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAACCTGCA GGAAGGGATTATCCCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGGTGTAA ACTTGTGATGGATCAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAACAAGAA CGGGACTGTCAAAAAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATGAAGAA TGATGGTGGGGGTGGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAAAGCAG AGGAACCCATGACATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTGTTAAA CCTGATCTGTGTCATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCAGCCTT CCGGTTTATAGACTGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGTTATCT CTCTACACTGAAAATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAGCAGTG CCACGGCACCAAGCGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCCCAAGT GAAATTGTTATATCGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCAGATCC TTGTTCTGAAGTACATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGTTAATA AAGGACTCAAAGAGGTTTTTG >2693_2693_4_AFF3-SAP130_AFF3_chr2_100720862_ENST00000356421_SAP130_chr2_128770729_ENST00000259234_length(amino acids)=843AA_BP= MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT QGLQPAPMGTQQPQPEGKTSVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQ PPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKK PRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDS MLKVLDHKDRVLKLLNKNGTVKKVSKLKRKEKV -------------------------------------------------------------- >2693_2693_5_AFF3-SAP130_AFF3_chr2_100720862_ENST00000356421_SAP130_chr2_128770729_ENST00000259235_length(transcript)=3435nt_BP=197nt CTGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGGCG GCCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAATGG GACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCAAA TGCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCTCC TGCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGTAG GCCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACACT ACCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCTGC AGCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGTAC CATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAGCA GATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCCAA TCCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCATA CCCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCTGC CATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGACA TATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTTGG CACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGAAA GACTTCAGCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACCGT GGTGCAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCCAC AGATGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTATCCAATCAAAATAATGA TCAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCCAGTCCCCCGTCACAACC AGCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCACCTCCATCAGTCACTGT GGGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATGGATATCATGAGGCCAGT TTCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATGCCTACAAGTGACCTACC ACCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATGGAGACAAACAGCACTGA TGATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATTGATGAGGAAGGTGTGAG ATATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTACCACCACTTTCAGAGGTA CAGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGTCGTGCTCAAGGCTGGAA AGTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAACCTGCAGGAAGGGATTAT CCCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGGTGTAAACTTGTGATGGA TCAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAACAAGAACGGGACTGTCAA AAAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATGAAGAATGATGGTGGGGG TGGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAAAGCAGAGGAACCCATGA CATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTGTTAAACCTGATCTGTGT CATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCAGCCTTCCGGTTTATAGA CTGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGTTATCTCTCTACACTGAA AATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAGCAGTGCCACGGCACCAA GCGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCCCAAGTGAAATTGTTATA TCGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCAGATCCTTGTTCTGAAGT ACATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGTTAATAAAGGACTCAAAG AGGTTTTTGTACTTG >2693_2693_5_AFF3-SAP130_AFF3_chr2_100720862_ENST00000356421_SAP130_chr2_128770729_ENST00000259235_length(amino acids)=809AA_BP= MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT QGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVS MATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPV PEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVK AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLT NLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRKEKV -------------------------------------------------------------- >2693_2693_6_AFF3-SAP130_AFF3_chr2_100720862_ENST00000356421_SAP130_chr2_128770729_ENST00000357702_length(transcript)=3541nt_BP=197nt CTGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGGCG GCCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAATGG GACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCAAA TGCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCTCC TGCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGTAG GCCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACACT ACCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCTGC AGCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGTAC CATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAGCA GATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCCAA TCCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCATA CCCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCTGC CATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGACA TATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTTGG CACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGAAA GACTTCAGCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACCGT GGTGCAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCCAC AGATGGAATGGCAGTTCGGAAAACCCTCATTCCTCCTCAGCCTCCTGATGTTGCTAGTCCTCGAGTGGAAAGCTCTATGCGGAGTACGTC TGGGTCACCTAGGCCTGCAGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTATC CAATCAAAATAATGATCAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCCAG TCCCCCGTCACAACCAGCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCACC TCCATCAGTCACTGTGGGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATGGA TATCATGAGGCCAGTTTCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATGCC TACAAGTGACCTACCACCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATGGA GACAAACAGCACTGATGATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATTGA TGAGGAAGGTGTGAGATATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTACCA CCACTTTCAGAGGTACAGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGTCG TGCTCAAGGCTGGAAAGTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAACCT GCAGGAAGGGATTATCCCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGGTG TAAACTTGTGATGGATCAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAACAA GAACGGGACTGTCAAAAAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATGAA GAATGATGGTGGGGGTGGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAAAG CAGAGGAACCCATGACATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTGTT AAACCTGATCTGTGTCATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCAGC CTTCCGGTTTATAGACTGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGTTA TCTCTCTACACTGAAAATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAGCA GTGCCACGGCACCAAGCGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCCCA AGTGAAATTGTTATATCGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCAGA TCCTTGTTCTGAAGTACATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGTTA ATAAAGGACTCAAAGAGGTTTTTGTACTTGC >2693_2693_6_AFF3-SAP130_AFF3_chr2_100720862_ENST00000356421_SAP130_chr2_128770729_ENST00000357702_length(amino acids)=844AA_BP= MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT QGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPP QPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTI PGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRK KPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKE EKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARD SMLKVLDHKDRVLKLLNKNGTVKKVSKLKRKEKV -------------------------------------------------------------- >2693_2693_7_AFF3-SAP130_AFF3_chr2_100720862_ENST00000409579_SAP130_chr2_128770729_ENST00000259234_length(transcript)=3620nt_BP=286nt AAATCCGATCTCAAATAGGAAAGAAGTCTCATTGGCCTTTTGGTCTTCTACCTGTGTCCTGAATTGAGTTTGTTAATCCTCATTCGGAGC TGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGGCGG CCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAATGGG ACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCAAAT GCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCTCCT GCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGTAGG CCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACACTA CCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCTGCA GCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGTACC ATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAGCAG ATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCCAAT CCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCATAC CCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCTGCC ATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGACAT ATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTTGGC ACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGAAAG ACTTCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACCGTGGTG CAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCCACAGAT GGAATGGCAGTTCGGAAAACCCTCATTCCTCCTCAGCCTCCTGATGTTGCTAGTCCTCGAGTGGAAAGCTCTATGCGGAGTACGTCTGGG TCACCTAGGCCTGCAGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTATCCAAT CAAAATAATGATCAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCCAGTCCC CCGTCACAACCAGCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCACCTCCA TCAGTCACTGTGGGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATGGATATC ATGAGGCCAGTTTCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATGCCTACA AGTGACCTACCACCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATGGAGACA AACAGCACTGATGATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATTGATGAG GAAGGTGTGAGATATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTACCACCAC TTTCAGAGGTACAGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGTCGTGCT CAAGGCTGGAAAGTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAACCTGCAG GAAGGGATTATCCCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGGTGTAAA CTTGTGATGGATCAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAACAAGAAC GGGACTGTCAAAAAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATGAAGAAT GATGGTGGGGGTGGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAAAGCAGA GGAACCCATGACATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTGTTAAAC CTGATCTGTGTCATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCAGCCTTC CGGTTTATAGACTGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGTTATCTC TCTACACTGAAAATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAGCAGTGC CACGGCACCAAGCGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCCCAAGTG AAATTGTTATATCGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCAGATCCT TGTTCTGAAGTACATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGTTAATAA AGGACTCAAAGAGGTTTTTG >2693_2693_7_AFF3-SAP130_AFF3_chr2_100720862_ENST00000409579_SAP130_chr2_128770729_ENST00000259234_length(amino acids)=843AA_BP= MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT QGLQPAPMGTQQPQPEGKTSVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQ PPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKK PRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDS MLKVLDHKDRVLKLLNKNGTVKKVSKLKRKEKV -------------------------------------------------------------- >2693_2693_8_AFF3-SAP130_AFF3_chr2_100720862_ENST00000409579_SAP130_chr2_128770729_ENST00000259235_length(transcript)=3524nt_BP=286nt AAATCCGATCTCAAATAGGAAAGAAGTCTCATTGGCCTTTTGGTCTTCTACCTGTGTCCTGAATTGAGTTTGTTAATCCTCATTCGGAGC TGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGGCGG CCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAATGGG ACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCAAAT GCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCTCCT GCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGTAGG CCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACACTA CCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCTGCA GCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGTACC ATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAGCAG ATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCCAAT CCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCATAC CCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCTGCC ATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGACAT ATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTTGGC ACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGAAAG ACTTCAGCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACCGTG GTGCAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCCACA GATGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTATCCAATCAAAATAATGAT CAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCCAGTCCCCCGTCACAACCA GCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCACCTCCATCAGTCACTGTG GGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATGGATATCATGAGGCCAGTT TCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATGCCTACAAGTGACCTACCA CCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATGGAGACAAACAGCACTGAT GATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATTGATGAGGAAGGTGTGAGA TATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTACCACCACTTTCAGAGGTAC AGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGTCGTGCTCAAGGCTGGAAA GTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAACCTGCAGGAAGGGATTATC CCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGGTGTAAACTTGTGATGGAT CAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAACAAGAACGGGACTGTCAAA AAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATGAAGAATGATGGTGGGGGT GGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAAAGCAGAGGAACCCATGAC ATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTGTTAAACCTGATCTGTGTC ATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCAGCCTTCCGGTTTATAGAC TGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGTTATCTCTCTACACTGAAA ATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAGCAGTGCCACGGCACCAAG CGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCCCAAGTGAAATTGTTATAT CGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCAGATCCTTGTTCTGAAGTA CATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGTTAATAAAGGACTCAAAGA GGTTTTTGTACTTG >2693_2693_8_AFF3-SAP130_AFF3_chr2_100720862_ENST00000409579_SAP130_chr2_128770729_ENST00000259235_length(amino acids)=809AA_BP= MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT QGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVS MATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPV PEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVK AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLT NLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRKEKV -------------------------------------------------------------- >2693_2693_9_AFF3-SAP130_AFF3_chr2_100720862_ENST00000409579_SAP130_chr2_128770729_ENST00000357702_length(transcript)=3630nt_BP=286nt AAATCCGATCTCAAATAGGAAAGAAGTCTCATTGGCCTTTTGGTCTTCTACCTGTGTCCTGAATTGAGTTTGTTAATCCTCATTCGGAGC TGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGGCGG CCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAATGGG ACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCAAAT GCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCTCCT GCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGTAGG CCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACACTA CCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCTGCA GCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGTACC ATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAGCAG ATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCCAAT CCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCATAC CCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCTGCC ATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGACAT ATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTTGGC ACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGAAAG ACTTCAGCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACCGTG GTGCAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCCACA GATGGAATGGCAGTTCGGAAAACCCTCATTCCTCCTCAGCCTCCTGATGTTGCTAGTCCTCGAGTGGAAAGCTCTATGCGGAGTACGTCT GGGTCACCTAGGCCTGCAGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTATCC AATCAAAATAATGATCAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCCAGT CCCCCGTCACAACCAGCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCACCT CCATCAGTCACTGTGGGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATGGAT ATCATGAGGCCAGTTTCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATGCCT ACAAGTGACCTACCACCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATGGAG ACAAACAGCACTGATGATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATTGAT GAGGAAGGTGTGAGATATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTACCAC CACTTTCAGAGGTACAGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGTCGT GCTCAAGGCTGGAAAGTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAACCTG CAGGAAGGGATTATCCCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGGTGT AAACTTGTGATGGATCAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAACAAG AACGGGACTGTCAAAAAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATGAAG AATGATGGTGGGGGTGGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAAAGC AGAGGAACCCATGACATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTGTTA AACCTGATCTGTGTCATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCAGCC TTCCGGTTTATAGACTGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGTTAT CTCTCTACACTGAAAATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAGCAG TGCCACGGCACCAAGCGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCCCAA GTGAAATTGTTATATCGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCAGAT CCTTGTTCTGAAGTACATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGTTAA TAAAGGACTCAAAGAGGTTTTTGTACTTGC >2693_2693_9_AFF3-SAP130_AFF3_chr2_100720862_ENST00000409579_SAP130_chr2_128770729_ENST00000357702_length(amino acids)=844AA_BP= MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT QGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPP QPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTI PGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRK KPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKE EKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARD SMLKVLDHKDRVLKLLNKNGTVKKVSKLKRKEKV -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for AFF3-SAP130 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for AFF3-SAP130 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for AFF3-SAP130 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | AFF3 | C0003873 | Rheumatoid Arthritis | 2 | CTD_human |
| Hgene | AFF3 | C0013146 | Drug abuse | 1 | CTD_human |
| Hgene | AFF3 | C0013170 | Drug habituation | 1 | CTD_human |
| Hgene | AFF3 | C0013222 | Drug Use Disorders | 1 | CTD_human |
| Hgene | AFF3 | C0029231 | Organic Mental Disorders, Substance-Induced | 1 | CTD_human |
| Hgene | AFF3 | C0036572 | Seizures | 1 | GENOMICS_ENGLAND |
| Hgene | AFF3 | C0038580 | Substance Dependence | 1 | CTD_human |
| Hgene | AFF3 | C0038586 | Substance Use Disorders | 1 | CTD_human |
| Hgene | AFF3 | C0236969 | Substance-Related Disorders | 1 | CTD_human |
| Hgene | AFF3 | C0740858 | Substance abuse problem | 1 | CTD_human |
| Hgene | AFF3 | C1510472 | Drug Dependence | 1 | CTD_human |
| Hgene | AFF3 | C3714756 | Intellectual Disability | 1 | GENOMICS_ENGLAND |
| Hgene | AFF3 | C4316881 | Prescription Drug Abuse | 1 | CTD_human |
| Tgene | C0152101 | Hypoplastic Left Heart Syndrome | 1 | CTD_human |
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