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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:LAMP1-F7 (FusionGDB2 ID:HG3916TG2155) |
Fusion Gene Summary for LAMP1-F7 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: LAMP1-F7 | Fusion gene ID: hg3916tg2155 | Hgene | Tgene | Gene symbol | LAMP1 | F7 | Gene ID | 3916 | 2155 |
| Gene name | lysosomal associated membrane protein 1 | coagulation factor VII | |
| Synonyms | CD107a|LAMPA|LGP120 | SPCA | |
| Cytomap | ('LAMP1')('F7') 13q34 | 13q34 | |
| Type of gene | protein-coding | protein-coding | |
| Description | lysosome-associated membrane glycoprotein 1CD107 antigen-like family member ALAMP-1lysosome-associated membrane protein 1 | coagulation factor VIIFVII coagulation proteincoagulation factor VII (serum prothrombin conversion accelerator)eptacog alfaproconvertin | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | P11279 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000332556, ENST00000397181, ENST00000471046, | ||
| Fusion gene scores | * DoF score | 10 X 10 X 6=600 | 4 X 4 X 4=64 |
| # samples | 10 | 5 | |
| ** MAII score | log2(10/600*10)=-2.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/64*10)=-0.356143810225275 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: LAMP1 [Title/Abstract] AND F7 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | LAMP1(113951810)-F7(113768161), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | LAMP1-F7 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. LAMP1-F7 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. LAMP1-F7 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. LAMP1-F7 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | F7 | GO:0002690 | positive regulation of leukocyte chemotaxis | 17991872 |
| Tgene | F7 | GO:0007596 | blood coagulation | 8632006|24998411 |
| Tgene | F7 | GO:0010641 | positive regulation of platelet-derived growth factor receptor signaling pathway | 17991872 |
| Tgene | F7 | GO:0016485 | protein processing | 24998411 |
| Tgene | F7 | GO:0050927 | positive regulation of positive chemotaxis | 17991872 |
| Tgene | F7 | GO:0051897 | positive regulation of protein kinase B signaling | 18612547 |
| Fusion gene breakpoints across LAMP1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across F7 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | SARC | TCGA-KF-A41W-01A | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
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Fusion Gene ORF analysis for LAMP1-F7 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-3UTR | ENST00000332556 | ENST00000473085 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| 5CDS-3UTR | ENST00000397181 | ENST00000473085 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| In-frame | ENST00000332556 | ENST00000346342 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| In-frame | ENST00000332556 | ENST00000375581 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| In-frame | ENST00000332556 | ENST00000541084 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| In-frame | ENST00000397181 | ENST00000346342 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| In-frame | ENST00000397181 | ENST00000375581 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| In-frame | ENST00000397181 | ENST00000541084 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| intron-3CDS | ENST00000471046 | ENST00000346342 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| intron-3CDS | ENST00000471046 | ENST00000375581 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| intron-3CDS | ENST00000471046 | ENST00000541084 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| intron-3UTR | ENST00000471046 | ENST00000473085 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000332556 | LAMP1 | chr13 | 113951810 | + | ENST00000541084 | F7 | chr13 | 113768161 | + | 1448 | 255 | 194 | 1339 | 381 |
| ENST00000332556 | LAMP1 | chr13 | 113951810 | + | ENST00000346342 | F7 | chr13 | 113768161 | + | 2363 | 255 | 194 | 1339 | 381 |
| ENST00000332556 | LAMP1 | chr13 | 113951810 | + | ENST00000375581 | F7 | chr13 | 113768161 | + | 3013 | 255 | 194 | 1339 | 381 |
| ENST00000397181 | LAMP1 | chr13 | 113951810 | + | ENST00000541084 | F7 | chr13 | 113768161 | + | 1304 | 111 | 50 | 1195 | 381 |
| ENST00000397181 | LAMP1 | chr13 | 113951810 | + | ENST00000346342 | F7 | chr13 | 113768161 | + | 2219 | 111 | 50 | 1195 | 381 |
| ENST00000397181 | LAMP1 | chr13 | 113951810 | + | ENST00000375581 | F7 | chr13 | 113768161 | + | 2869 | 111 | 50 | 1195 | 381 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000332556 | ENST00000541084 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + | 0.045948748 | 0.95405126 |
| ENST00000332556 | ENST00000346342 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + | 0.028402537 | 0.97159743 |
| ENST00000332556 | ENST00000375581 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + | 0.038365953 | 0.96163404 |
| ENST00000397181 | ENST00000541084 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + | 0.046738196 | 0.95326185 |
| ENST00000397181 | ENST00000346342 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + | 0.030130686 | 0.9698693 |
| ENST00000397181 | ENST00000375581 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + | 0.038955163 | 0.96104485 |
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Fusion Genomic Features for LAMP1-F7 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768160 | + | 1.52E-05 | 0.99998474 |
| LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768160 | + | 1.52E-05 | 0.99998474 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for LAMP1-F7 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:113951810/chr13:113768161) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| LAMP1 | . |
| FUNCTION: Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.; FUNCTION: Acts as a receptor for Lassa virus protein. {ECO:0000269|PubMed:24970085}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | F7 | chr13:113951810 | chr13:113768161 | ENST00000346342 | 2 | 8 | 106_142 | 83 | 445.0 | Domain | EGF-like 1%3B calcium-binding | |
| Tgene | F7 | chr13:113951810 | chr13:113768161 | ENST00000346342 | 2 | 8 | 147_188 | 83 | 445.0 | Domain | EGF-like 2 | |
| Tgene | F7 | chr13:113951810 | chr13:113768161 | ENST00000346342 | 2 | 8 | 213_452 | 83 | 445.0 | Domain | Peptidase S1 | |
| Tgene | F7 | chr13:113951810 | chr13:113768161 | ENST00000375581 | 3 | 9 | 106_142 | 105 | 467.0 | Domain | EGF-like 1%3B calcium-binding | |
| Tgene | F7 | chr13:113951810 | chr13:113768161 | ENST00000375581 | 3 | 9 | 147_188 | 105 | 467.0 | Domain | EGF-like 2 | |
| Tgene | F7 | chr13:113951810 | chr13:113768161 | ENST00000375581 | 3 | 9 | 213_452 | 105 | 467.0 | Domain | Peptidase S1 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | LAMP1 | chr13:113951810 | chr13:113768161 | ENST00000332556 | + | 1 | 9 | 195_227 | 20 | 418.0 | Region | Note=Hinge |
| Hgene | LAMP1 | chr13:113951810 | chr13:113768161 | ENST00000332556 | + | 1 | 9 | 228_382 | 20 | 418.0 | Region | Note=Second lumenal domain |
| Hgene | LAMP1 | chr13:113951810 | chr13:113768161 | ENST00000332556 | + | 1 | 9 | 29_194 | 20 | 418.0 | Region | Note=First lumenal domain |
| Hgene | LAMP1 | chr13:113951810 | chr13:113768161 | ENST00000332556 | + | 1 | 9 | 29_382 | 20 | 418.0 | Topological domain | Lumenal |
| Hgene | LAMP1 | chr13:113951810 | chr13:113768161 | ENST00000332556 | + | 1 | 9 | 406_417 | 20 | 418.0 | Topological domain | Cytoplasmic |
| Hgene | LAMP1 | chr13:113951810 | chr13:113768161 | ENST00000332556 | + | 1 | 9 | 383_405 | 20 | 418.0 | Transmembrane | Helical |
| Tgene | F7 | chr13:113951810 | chr13:113768161 | ENST00000346342 | 2 | 8 | 61_105 | 83 | 445.0 | Domain | Gla | |
| Tgene | F7 | chr13:113951810 | chr13:113768161 | ENST00000375581 | 3 | 9 | 61_105 | 105 | 467.0 | Domain | Gla |
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Fusion Gene Sequence for LAMP1-F7 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >43980_43980_1_LAMP1-F7_LAMP1_chr13_113951810_ENST00000332556_F7_chr13_113768161_ENST00000346342_length(transcript)=2363nt_BP=255nt GTGACAAGCGCTGCCGGCCGCGGTGTCTTCTTCGTGCCGGCGTCGCAGTGGCCGGGCCTCTTGCGTCTGGTAACGCCGCTGTCTCTAACG CCAGCCCTTGGCGCCCGCGCCCCGCCACCGCAGCGCCCGGCAGTCCGCGGCCCAACCGCCGCCCGCGCCCCCGCTCCCCGCACCGTACCC GGCCGCCTCGCGCCATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGCTACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTG CCTCAAGTCCATGCCAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATATCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACT GTGAGACGCACAAGGATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTGAGCAGTACTGCAGTGACCACACGGGCACCAAGCGCT CCTGTCGGTGCCACGAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACACCCACAGTTGAATATCCATGTGGAAAAATACCTATTC TAGAAAAAAGAAATGCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGTGCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGT TGGTGAATGGAGCTCAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGGTCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACT GGAGGAACCTGATCGCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGGATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCC CCAGCACGTACGTCCCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGCACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCC TCTGCCTGCCCGAACGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCTCATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTG GCGCCACGGCCCTGGAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGGACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCC CAAATATCACGGAGTACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACTCCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCC ACTACCGGGGCACGTGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCGCAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCT CCCAGTACATCGAGTGGCTGCAAAAGCTCATGCGCTCAGAGCCACGCCCAGGAGTCCTCCTGCGAGCCCCATTTCCCTAGCCCAGCAGCC CTGGCCTGTGGAGAGAAAGCCAAGGCTGCGTCGAACTGTCCTGGCACCAAATCCCATATATTCTTCTGCAGTTAATGGGGTAGAGGAGGG CATGGGAGGGAGGGAGAGGTGGGGAGGGAGACAGAGACAGAAACAGAGAGAGACAGAGACAGAGAGAGACTGAGGGAGAGACTCTGAGGA CATGGAGAGAGACTCAAAGAGACTCCAAGATTCAAAGAGACTAATAGAGACACAGAGATGGAATAGAAAAGATGAGAGGCAGAGGCAGAC AGGCGCTGGACAGAGGGGCAGGGGAGTGCCAAGGTTGTCCTGGAGGCAGACAGCCCAGCTGAGCCTCCTTACCTCCCTTCAGCCAAGCCC ACCTGCACGTGATCTGCTGGCCTCAGGCTGCTGCTCTGCCTTCATTGCTGGAGACAGTAGAGGCATGAACACACATGGATGCACACACAC ACACGCCAATGCACACACACAGAGATATGCACACACACGGATGCACACACAGATGGTCACACAGAGATACGCAAACACACCGATGCACAC GCACATAGAGATATGCACACACAGATGCACACACAGATATACACATGGATGCACGCACATGCCAATGCACGCACACATCAGTGCACACGG ATGCACAGAGATATGCACACACCGATGTGCGCACACACAGATATGCACACACATGGATGAGCACACACACACCAATGCGCACACACACCG ATGTACACACACAGATGCACACACAGATGCACACACACCGATGCTGACTCCATGTGTGCTGTCCTCTGAAGGCGGTTGTTTAGCTCTCAC TTTTCTGGTTCTTATCCATTATCATCTTCACTTCAGACAATTCAGAAGCATCACCATGCATGGTGGCGAATGCCCCCAAACTCTCCCCCA AATGTATTTCTCCCTTCGCTGGGTGCCGGGCTGCACAGACTATTCCCCACCTGCTTCCCAGCTTCACAATAAACGGCTGCGTCTCCTCCG >43980_43980_1_LAMP1-F7_LAMP1_chr13_113951810_ENST00000332556_F7_chr13_113768161_ENST00000346342_length(amino acids)=381AA_BP=20 MAAPGSARRPLLLLLLLLLLDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCH EGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLI AVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATAL ELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIE -------------------------------------------------------------- >43980_43980_2_LAMP1-F7_LAMP1_chr13_113951810_ENST00000332556_F7_chr13_113768161_ENST00000375581_length(transcript)=3013nt_BP=255nt GTGACAAGCGCTGCCGGCCGCGGTGTCTTCTTCGTGCCGGCGTCGCAGTGGCCGGGCCTCTTGCGTCTGGTAACGCCGCTGTCTCTAACG CCAGCCCTTGGCGCCCGCGCCCCGCCACCGCAGCGCCCGGCAGTCCGCGGCCCAACCGCCGCCCGCGCCCCCGCTCCCCGCACCGTACCC GGCCGCCTCGCGCCATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGCTACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTG CCTCAAGTCCATGCCAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATATCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACT GTGAGACGCACAAGGATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTGAGCAGTACTGCAGTGACCACACGGGCACCAAGCGCT CCTGTCGGTGCCACGAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACACCCACAGTTGAATATCCATGTGGAAAAATACCTATTC TAGAAAAAAGAAATGCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGTGCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGT TGGTGAATGGAGCTCAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGGTCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACT GGAGGAACCTGATCGCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGGATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCC CCAGCACGTACGTCCCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGCACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCC TCTGCCTGCCCGAACGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCTCATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTG GCGCCACGGCCCTGGAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGGACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCC CAAATATCACGGAGTACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACTCCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCC ACTACCGGGGCACGTGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCGCAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCT CCCAGTACATCGAGTGGCTGCAAAAGCTCATGCGCTCAGAGCCACGCCCAGGAGTCCTCCTGCGAGCCCCATTTCCCTAGCCCAGCAGCC CTGGCCTGTGGAGAGAAAGCCAAGGCTGCGTCGAACTGTCCTGGCACCAAATCCCATATATTCTTCTGCAGTTAATGGGGTAGAGGAGGG CATGGGAGGGAGGGAGAGGTGGGGAGGGAGACAGAGACAGAAACAGAGAGAGACAGAGACAGAGAGAGACTGAGGGAGAGACTCTGAGGA CATGGAGAGAGACTCAAAGAGACTCCAAGATTCAAAGAGACTAATAGAGACACAGAGATGGAATAGAAAAGATGAGAGGCAGAGGCAGAC AGGCGCTGGACAGAGGGGCAGGGGAGTGCCAAGGTTGTCCTGGAGGCAGACAGCCCAGCTGAGCCTCCTTACCTCCCTTCAGCCAAGCCC ACCTGCACGTGATCTGCTGGCCTCAGGCTGCTGCTCTGCCTTCATTGCTGGAGACAGTAGAGGCATGAACACACATGGATGCACACACAC ACACGCCAATGCACACACACAGAGATATGCACACACACGGATGCACACACAGATGGTCACACAGAGATACGCAAACACACCGATGCACAC GCACATAGAGATATGCACACACAGATGCACACACAGATATACACATGGATGCACGCACATGCCAATGCACGCACACATCAGTGCACACGG ATGCACAGAGATATGCACACACCGATGTGCGCACACACAGATATGCACACACATGGATGAGCACACACACACCAATGCGCACACACACCG ATGTACACACACAGATGCACACACAGATGCACACACACCGATGCTGACTCCATGTGTGCTGTCCTCTGAAGGCGGTTGTTTAGCTCTCAC TTTTCTGGTTCTTATCCATTATCATCTTCACTTCAGACAATTCAGAAGCATCACCATGCATGGTGGCGAATGCCCCCAAACTCTCCCCCA AATGTATTTCTCCCTTCGCTGGGTGCCGGGCTGCACAGACTATTCCCCACCTGCTTCCCAGCTTCACAATAAACGGCTGCGTCTCCTCCG CACACCTGTGGTGCCTGCCACCCACTGGGTTGCCCATGATTCATTTTTGGAGCCCCCGGTGCTCATCCTCTGAGATGCTCTTTTCTTTCA CAATTTTCAACATCACTGAAATGAACCCTCACATGGAAGCTATTTTTTAAAAACAAAAGCTGTTTGATAGATGTTTGAGGCTGTAGCTCC CAGGATCCTGTGGAATTGGATGTTCTCTCCCTGCCACAGCCCTTGTCAATGATATTTCACAGAGACCCTGGGAGCACCTGCTCAAGAGTC AGGGACACACGCATCACTAAATGCAAGTTCCCAGGCCCTGGCTGCAGTGGGAGGACCTGGCAAGCTGCACTCTTGCTGAGTCCCCAGGGT GGTGGAAGAAGAATGAGAAACACATGAACAGAGAAATGGGGAGGTGACAAACAGTGCCCCCACTCAGACTCCGGCAAGCACGGCTCAGAG AGTGGACTCGATGCCATCCCTGCAGGGCCGTCCTGGGCACCACTGGCACTCACAGCAGCAAGGTGGGCACCATTGGCACTCACAGCAGCA AGGCAGGCACCAGCAACCCACCTCGGGGGCACTCAGGCATCATCTACTTCAGAGCAGACAGGGTCTATGAACTACAGCCGTGGGCTGCTT >43980_43980_2_LAMP1-F7_LAMP1_chr13_113951810_ENST00000332556_F7_chr13_113768161_ENST00000375581_length(amino acids)=381AA_BP=20 MAAPGSARRPLLLLLLLLLLDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCH EGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLI AVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATAL ELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIE -------------------------------------------------------------- >43980_43980_3_LAMP1-F7_LAMP1_chr13_113951810_ENST00000332556_F7_chr13_113768161_ENST00000541084_length(transcript)=1448nt_BP=255nt GTGACAAGCGCTGCCGGCCGCGGTGTCTTCTTCGTGCCGGCGTCGCAGTGGCCGGGCCTCTTGCGTCTGGTAACGCCGCTGTCTCTAACG CCAGCCCTTGGCGCCCGCGCCCCGCCACCGCAGCGCCCGGCAGTCCGCGGCCCAACCGCCGCCCGCGCCCCCGCTCCCCGCACCGTACCC GGCCGCCTCGCGCCATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGCTACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTG CCTCAAGTCCATGCCAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATATCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACT GTGAGACGCACAAGGATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTGAGCAGTACTGCAGTGACCACACGGGCACCAAGCGCT CCTGTCGGTGCCACGAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACACCCACAGTTGAATATCCATGTGGAAAAATACCTATTC TAGAAAAAAGAAATGCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGTGCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGT TGGTGAATGGAGCTCAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGGTCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACT GGAGGAACCTGATCGCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGGATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCC CCAGCACGTACGTCCCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGCACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCC TCTGCCTGCCCGAACGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCTCATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTG GCGCCACGGCCCTGGAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGGACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCC CAAATATCACGGAGTACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACTCCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCC ACTACCGGGGCACGTGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCGCAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCT CCCAGTACATCGAGTGGCTGCAAAAGCTCATGCGCTCAGAGCCACGCCCAGGAGTCCTCCTGCGAGCCCCATTTCCCTAGCCCAGCAGCC CTGGCCTGTGGAGAGAAAGCCAAGGCTGCGTCGAACTGTCCTGGCACCAAATCCCATATATTCTTCTGCAGTTAATGGGGTAGAGGAGGG >43980_43980_3_LAMP1-F7_LAMP1_chr13_113951810_ENST00000332556_F7_chr13_113768161_ENST00000541084_length(amino acids)=381AA_BP=20 MAAPGSARRPLLLLLLLLLLDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCH EGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLI AVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATAL ELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIE -------------------------------------------------------------- >43980_43980_4_LAMP1-F7_LAMP1_chr13_113951810_ENST00000397181_F7_chr13_113768161_ENST00000346342_length(transcript)=2219nt_BP=111nt ACCGCCGCCCGCGCCCCCGCTCCCCGCACCGTACCCGGCCGCCTCGCGCCATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGC TACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTGCCTCAAGTCCATGCCAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATA TCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACTGTGAGACGCACAAGGATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTG AGCAGTACTGCAGTGACCACACGGGCACCAAGCGCTCCTGTCGGTGCCACGAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACAC CCACAGTTGAATATCCATGTGGAAAAATACCTATTCTAGAAAAAAGAAATGCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGT GCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGTTGGTGAATGGAGCTCAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGG TCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACTGGAGGAACCTGATCGCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGG ATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCCCCAGCACGTACGTCCCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGC ACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCCTCTGCCTGCCCGAACGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCT CATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTGGCGCCACGGCCCTGGAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGG ACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCCCAAATATCACGGAGTACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACT CCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCCACTACCGGGGCACGTGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCG CAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCTCCCAGTACATCGAGTGGCTGCAAAAGCTCATGCGCTCAGAGCCACGCCCAGGAG TCCTCCTGCGAGCCCCATTTCCCTAGCCCAGCAGCCCTGGCCTGTGGAGAGAAAGCCAAGGCTGCGTCGAACTGTCCTGGCACCAAATCC CATATATTCTTCTGCAGTTAATGGGGTAGAGGAGGGCATGGGAGGGAGGGAGAGGTGGGGAGGGAGACAGAGACAGAAACAGAGAGAGAC AGAGACAGAGAGAGACTGAGGGAGAGACTCTGAGGACATGGAGAGAGACTCAAAGAGACTCCAAGATTCAAAGAGACTAATAGAGACACA GAGATGGAATAGAAAAGATGAGAGGCAGAGGCAGACAGGCGCTGGACAGAGGGGCAGGGGAGTGCCAAGGTTGTCCTGGAGGCAGACAGC CCAGCTGAGCCTCCTTACCTCCCTTCAGCCAAGCCCACCTGCACGTGATCTGCTGGCCTCAGGCTGCTGCTCTGCCTTCATTGCTGGAGA CAGTAGAGGCATGAACACACATGGATGCACACACACACACGCCAATGCACACACACAGAGATATGCACACACACGGATGCACACACAGAT GGTCACACAGAGATACGCAAACACACCGATGCACACGCACATAGAGATATGCACACACAGATGCACACACAGATATACACATGGATGCAC GCACATGCCAATGCACGCACACATCAGTGCACACGGATGCACAGAGATATGCACACACCGATGTGCGCACACACAGATATGCACACACAT GGATGAGCACACACACACCAATGCGCACACACACCGATGTACACACACAGATGCACACACAGATGCACACACACCGATGCTGACTCCATG TGTGCTGTCCTCTGAAGGCGGTTGTTTAGCTCTCACTTTTCTGGTTCTTATCCATTATCATCTTCACTTCAGACAATTCAGAAGCATCAC CATGCATGGTGGCGAATGCCCCCAAACTCTCCCCCAAATGTATTTCTCCCTTCGCTGGGTGCCGGGCTGCACAGACTATTCCCCACCTGC >43980_43980_4_LAMP1-F7_LAMP1_chr13_113951810_ENST00000397181_F7_chr13_113768161_ENST00000346342_length(amino acids)=381AA_BP=20 MAAPGSARRPLLLLLLLLLLDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCH EGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLI AVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATAL ELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIE -------------------------------------------------------------- >43980_43980_5_LAMP1-F7_LAMP1_chr13_113951810_ENST00000397181_F7_chr13_113768161_ENST00000375581_length(transcript)=2869nt_BP=111nt ACCGCCGCCCGCGCCCCCGCTCCCCGCACCGTACCCGGCCGCCTCGCGCCATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGC TACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTGCCTCAAGTCCATGCCAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATA TCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACTGTGAGACGCACAAGGATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTG AGCAGTACTGCAGTGACCACACGGGCACCAAGCGCTCCTGTCGGTGCCACGAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACAC CCACAGTTGAATATCCATGTGGAAAAATACCTATTCTAGAAAAAAGAAATGCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGT GCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGTTGGTGAATGGAGCTCAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGG TCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACTGGAGGAACCTGATCGCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGG ATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCCCCAGCACGTACGTCCCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGC ACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCCTCTGCCTGCCCGAACGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCT CATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTGGCGCCACGGCCCTGGAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGG ACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCCCAAATATCACGGAGTACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACT CCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCCACTACCGGGGCACGTGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCG CAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCTCCCAGTACATCGAGTGGCTGCAAAAGCTCATGCGCTCAGAGCCACGCCCAGGAG TCCTCCTGCGAGCCCCATTTCCCTAGCCCAGCAGCCCTGGCCTGTGGAGAGAAAGCCAAGGCTGCGTCGAACTGTCCTGGCACCAAATCC CATATATTCTTCTGCAGTTAATGGGGTAGAGGAGGGCATGGGAGGGAGGGAGAGGTGGGGAGGGAGACAGAGACAGAAACAGAGAGAGAC AGAGACAGAGAGAGACTGAGGGAGAGACTCTGAGGACATGGAGAGAGACTCAAAGAGACTCCAAGATTCAAAGAGACTAATAGAGACACA GAGATGGAATAGAAAAGATGAGAGGCAGAGGCAGACAGGCGCTGGACAGAGGGGCAGGGGAGTGCCAAGGTTGTCCTGGAGGCAGACAGC CCAGCTGAGCCTCCTTACCTCCCTTCAGCCAAGCCCACCTGCACGTGATCTGCTGGCCTCAGGCTGCTGCTCTGCCTTCATTGCTGGAGA CAGTAGAGGCATGAACACACATGGATGCACACACACACACGCCAATGCACACACACAGAGATATGCACACACACGGATGCACACACAGAT GGTCACACAGAGATACGCAAACACACCGATGCACACGCACATAGAGATATGCACACACAGATGCACACACAGATATACACATGGATGCAC GCACATGCCAATGCACGCACACATCAGTGCACACGGATGCACAGAGATATGCACACACCGATGTGCGCACACACAGATATGCACACACAT GGATGAGCACACACACACCAATGCGCACACACACCGATGTACACACACAGATGCACACACAGATGCACACACACCGATGCTGACTCCATG TGTGCTGTCCTCTGAAGGCGGTTGTTTAGCTCTCACTTTTCTGGTTCTTATCCATTATCATCTTCACTTCAGACAATTCAGAAGCATCAC CATGCATGGTGGCGAATGCCCCCAAACTCTCCCCCAAATGTATTTCTCCCTTCGCTGGGTGCCGGGCTGCACAGACTATTCCCCACCTGC TTCCCAGCTTCACAATAAACGGCTGCGTCTCCTCCGCACACCTGTGGTGCCTGCCACCCACTGGGTTGCCCATGATTCATTTTTGGAGCC CCCGGTGCTCATCCTCTGAGATGCTCTTTTCTTTCACAATTTTCAACATCACTGAAATGAACCCTCACATGGAAGCTATTTTTTAAAAAC AAAAGCTGTTTGATAGATGTTTGAGGCTGTAGCTCCCAGGATCCTGTGGAATTGGATGTTCTCTCCCTGCCACAGCCCTTGTCAATGATA TTTCACAGAGACCCTGGGAGCACCTGCTCAAGAGTCAGGGACACACGCATCACTAAATGCAAGTTCCCAGGCCCTGGCTGCAGTGGGAGG ACCTGGCAAGCTGCACTCTTGCTGAGTCCCCAGGGTGGTGGAAGAAGAATGAGAAACACATGAACAGAGAAATGGGGAGGTGACAAACAG TGCCCCCACTCAGACTCCGGCAAGCACGGCTCAGAGAGTGGACTCGATGCCATCCCTGCAGGGCCGTCCTGGGCACCACTGGCACTCACA GCAGCAAGGTGGGCACCATTGGCACTCACAGCAGCAAGGCAGGCACCAGCAACCCACCTCGGGGGCACTCAGGCATCATCTACTTCAGAG >43980_43980_5_LAMP1-F7_LAMP1_chr13_113951810_ENST00000397181_F7_chr13_113768161_ENST00000375581_length(amino acids)=381AA_BP=20 MAAPGSARRPLLLLLLLLLLDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCH EGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLI AVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATAL ELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIE -------------------------------------------------------------- >43980_43980_6_LAMP1-F7_LAMP1_chr13_113951810_ENST00000397181_F7_chr13_113768161_ENST00000541084_length(transcript)=1304nt_BP=111nt ACCGCCGCCCGCGCCCCCGCTCCCCGCACCGTACCCGGCCGCCTCGCGCCATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGC TACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTGCCTCAAGTCCATGCCAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATA TCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACTGTGAGACGCACAAGGATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTG AGCAGTACTGCAGTGACCACACGGGCACCAAGCGCTCCTGTCGGTGCCACGAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACAC CCACAGTTGAATATCCATGTGGAAAAATACCTATTCTAGAAAAAAGAAATGCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGT GCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGTTGGTGAATGGAGCTCAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGG TCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACTGGAGGAACCTGATCGCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGG ATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCCCCAGCACGTACGTCCCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGC ACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCCTCTGCCTGCCCGAACGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCT CATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTGGCGCCACGGCCCTGGAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGG ACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCCCAAATATCACGGAGTACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACT CCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCCACTACCGGGGCACGTGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCG CAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCTCCCAGTACATCGAGTGGCTGCAAAAGCTCATGCGCTCAGAGCCACGCCCAGGAG TCCTCCTGCGAGCCCCATTTCCCTAGCCCAGCAGCCCTGGCCTGTGGAGAGAAAGCCAAGGCTGCGTCGAACTGTCCTGGCACCAAATCC >43980_43980_6_LAMP1-F7_LAMP1_chr13_113951810_ENST00000397181_F7_chr13_113768161_ENST00000541084_length(amino acids)=381AA_BP=20 MAAPGSARRPLLLLLLLLLLDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCH EGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLI AVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATAL ELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIE -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for LAMP1-F7 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for LAMP1-F7 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for LAMP1-F7 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | C0015503 | Factor VII Deficiency | 34 | CLINGEN;CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT | |
| Tgene | C0151699 | Intracranial Hemorrhage | 5 | CTD_human | |
| Tgene | C0553692 | Brain hemorrhage | 5 | CTD_human | |
| Tgene | C0751893 | Posterior Fossa Hemorrhage | 5 | CTD_human | |
| Tgene | C0019080 | Hemorrhage | 3 | CTD_human | |
| Tgene | C2937358 | Cerebral Hemorrhage | 2 | CTD_human | |
| Tgene | C0012739 | Disseminated Intravascular Coagulation | 1 | CTD_human | |
| Tgene | C0018965 | Hematuria | 1 | CTD_human | |
| Tgene | C0019087 | Hemorrhagic Disorders | 1 | CTD_human | |
| Tgene | C0032787 | Postoperative Complications | 1 | CTD_human | |
| Tgene | C0040038 | Thromboembolism | 1 | CTD_human | |
| Tgene | C0042487 | Venous Thrombosis | 1 | CTD_human | |
| Tgene | C0149871 | Deep Vein Thrombosis | 1 | CTD_human | |
| Tgene | C0749098 | Hematoma, Subdural, Acute | 1 | CTD_human | |
| Tgene | C0751797 | Intracranial Hematoma, Traumatic | 1 | CTD_human |
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