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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:CD46-CD55 (FusionGDB2 ID:HG4179TG1604)

Fusion Gene Summary for CD46-CD55

Fusion gene summary

Fusion gene information	Fusion gene name: CD46-CD55
	Fusion gene ID: hg4179tg1604
		Hgene	Tgene
	Gene symbol	CD46	CD55
	Gene ID	4179	1604
	Gene name	CD46 molecule	CD55 molecule (Cromer blood group)
	Synonyms	AHUS2\|MCP\|MIC10\|TLX\|TRA2.10	CHAPLE\|CR\|CROM\|DAF\|TC
	Cytomap	('CD46')('CD55') 1q32.2	1q32.2
	Type of gene	protein-coding	protein-coding
	Description	membrane cofactor proteinCD46 antigen, complement regulatory proteinCD46 molecule, complement regulatory proteinantigen identified by monoclonal antibody TRA-2-10complement membrane cofactor proteinmeasles virus receptormembrane cofactor protein (CD	complement decay-accelerating factorCD55 antigenCD55 molecule, decay accelerating factor for complement (Cromer blood group)Cromer blood group antigen
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000469535, ENST00000322875, ENST00000322918, ENST00000354848, ENST00000357714, ENST00000358170, ENST00000367041, ENST00000367042, ENST00000367047, ENST00000441839, ENST00000360212, ENST00000361067, ENST00000480003,
Fusion gene scores	* DoF score	12 X 12 X 6=864	10 X 8 X 4=320
	# samples	14	10
	** MAII score	log2(14/864*10)=-2.6256044852185 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(10/320*10)=-1.67807190511264 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: CD46 [Title/Abstract] AND CD55 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	CD46(207943707)-CD55(207497904), # samples:1
Anticipated loss of major functional domain due to fusion event.	CD46-CD55 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CD46-CD55 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CD46-CD55 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CD46-CD55 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	CD46	GO:0008593	regulation of Notch signaling pathway	23086448
Hgene	CD46	GO:0010629	negative regulation of gene expression	23086448
Hgene	CD46	GO:0032613	interleukin-10 production	23086448
Hgene	CD46	GO:0032733	positive regulation of interleukin-10 production	12540904
Hgene	CD46	GO:0035581	sequestering of extracellular ligand from receptor	23086448
Hgene	CD46	GO:0042102	positive regulation of T cell proliferation	12540904
Hgene	CD46	GO:0043382	positive regulation of memory T cell differentiation	12540904
Hgene	CD46	GO:0045591	positive regulation of regulatory T cell differentiation	12540904
Hgene	CD46	GO:0071636	positive regulation of transforming growth factor beta production	12540904
Tgene	CD55	GO:0007204	positive regulation of cytosolic calcium ion concentration	8223854
Tgene	CD55	GO:0030449	regulation of complement activation	25284781
Tgene	CD55	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	12731067
Tgene	CD55	GO:0035743	CD4-positive, alpha-beta T cell cytokine production	16818763
Tgene	CD55	GO:0045916	negative regulation of complement activation	6211481
Tgene	CD55	GO:1903659	regulation of complement-dependent cytotoxicity	25284781
Tgene	CD55	GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	16818763
Tgene	CD55	GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation	16818763

Fusion gene breakpoints across CD46 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across CD55 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	LIHC	TCGA-DD-A4NB-01A	CD46	chr1	207943707	+	CD55	chr1	207497904	+

Top

Fusion Gene ORF analysis for CD46-CD55

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
3UTR-3CDS	ENST00000469535	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+
3UTR-3CDS	ENST00000469535	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+
3UTR-intron	ENST00000469535	ENST00000314754	CD46	chr1	207943707	+	CD55	chr1	207497904	+
3UTR-intron	ENST00000469535	ENST00000367062	CD46	chr1	207943707	+	CD55	chr1	207497904	+
3UTR-intron	ENST00000469535	ENST00000367065	CD46	chr1	207943707	+	CD55	chr1	207497904	+
3UTR-intron	ENST00000469535	ENST00000367067	CD46	chr1	207943707	+	CD55	chr1	207497904	+
3UTR-intron	ENST00000469535	ENST00000391920	CD46	chr1	207943707	+	CD55	chr1	207497904	+
3UTR-intron	ENST00000469535	ENST00000391921	CD46	chr1	207943707	+	CD55	chr1	207497904	+
3UTR-intron	ENST00000469535	ENST00000465534	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000322875	ENST00000314754	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000322875	ENST00000367062	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000322875	ENST00000367065	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000322875	ENST00000367067	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000322875	ENST00000391920	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000322875	ENST00000391921	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000322875	ENST00000465534	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000322918	ENST00000314754	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000322918	ENST00000367062	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000322918	ENST00000367065	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000322918	ENST00000367067	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000322918	ENST00000391920	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000322918	ENST00000391921	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000322918	ENST00000465534	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000354848	ENST00000314754	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000354848	ENST00000367062	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000354848	ENST00000367065	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000354848	ENST00000367067	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000354848	ENST00000391920	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000354848	ENST00000391921	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000354848	ENST00000465534	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000357714	ENST00000314754	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000357714	ENST00000367062	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000357714	ENST00000367065	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000357714	ENST00000367067	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000357714	ENST00000391920	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000357714	ENST00000391921	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000357714	ENST00000465534	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000358170	ENST00000314754	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000358170	ENST00000367062	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000358170	ENST00000367065	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000358170	ENST00000367067	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000358170	ENST00000391920	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000358170	ENST00000391921	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000358170	ENST00000465534	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367041	ENST00000314754	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367041	ENST00000367062	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367041	ENST00000367065	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367041	ENST00000367067	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367041	ENST00000391920	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367041	ENST00000391921	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367041	ENST00000465534	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367042	ENST00000314754	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367042	ENST00000367062	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367042	ENST00000367065	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367042	ENST00000367067	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367042	ENST00000391920	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367042	ENST00000391921	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367042	ENST00000465534	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367047	ENST00000314754	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367047	ENST00000367062	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367047	ENST00000367065	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367047	ENST00000367067	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367047	ENST00000391920	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367047	ENST00000391921	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000367047	ENST00000465534	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000441839	ENST00000314754	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000441839	ENST00000367062	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000441839	ENST00000367065	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000441839	ENST00000367067	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000441839	ENST00000391920	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000441839	ENST00000391921	CD46	chr1	207943707	+	CD55	chr1	207497904	+
5CDS-intron	ENST00000441839	ENST00000465534	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000322875	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000322875	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000322918	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000322918	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000354848	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000354848	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000357714	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000357714	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000358170	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000358170	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000367041	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000367041	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000367042	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000367042	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000367047	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000367047	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000441839	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+
In-frame	ENST00000441839	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-3CDS	ENST00000360212	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-3CDS	ENST00000360212	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-3CDS	ENST00000361067	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-3CDS	ENST00000361067	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-3CDS	ENST00000480003	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-3CDS	ENST00000480003	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000360212	ENST00000314754	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000360212	ENST00000367062	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000360212	ENST00000367065	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000360212	ENST00000367067	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000360212	ENST00000391920	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000360212	ENST00000391921	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000360212	ENST00000465534	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000361067	ENST00000314754	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000361067	ENST00000367062	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000361067	ENST00000367065	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000361067	ENST00000367067	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000361067	ENST00000391920	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000361067	ENST00000391921	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000361067	ENST00000465534	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000480003	ENST00000314754	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000480003	ENST00000367062	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000480003	ENST00000367065	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000480003	ENST00000367067	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000480003	ENST00000391920	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000480003	ENST00000391921	CD46	chr1	207943707	+	CD55	chr1	207497904	+
intron-intron	ENST00000480003	ENST00000465534	CD46	chr1	207943707	+	CD55	chr1	207497904	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000367042	CD46	chr1	207943707	+	ENST00000367064	CD55	chr1	207497904	+	3315	1099	69	1958	629
ENST00000367042	CD46	chr1	207943707	+	ENST00000367063	CD55	chr1	207497904	+	2270	1099	69	2147	692
ENST00000354848	CD46	chr1	207943707	+	ENST00000367064	CD55	chr1	207497904	+	3315	1099	69	1958	629
ENST00000354848	CD46	chr1	207943707	+	ENST00000367063	CD55	chr1	207497904	+	2270	1099	69	2147	692
ENST00000441839	CD46	chr1	207943707	+	ENST00000367064	CD55	chr1	207497904	+	3315	1099	69	1958	629
ENST00000441839	CD46	chr1	207943707	+	ENST00000367063	CD55	chr1	207497904	+	2270	1099	69	2147	692
ENST00000322875	CD46	chr1	207943707	+	ENST00000367064	CD55	chr1	207497904	+	3360	1144	69	2003	644
ENST00000322875	CD46	chr1	207943707	+	ENST00000367063	CD55	chr1	207497904	+	2315	1144	69	2192	707
ENST00000367041	CD46	chr1	207943707	+	ENST00000367064	CD55	chr1	207497904	+	3270	1054	69	1913	614
ENST00000367041	CD46	chr1	207943707	+	ENST00000367063	CD55	chr1	207497904	+	2225	1054	69	2102	677
ENST00000358170	CD46	chr1	207943707	+	ENST00000367064	CD55	chr1	207497904	+	3360	1144	69	2003	644
ENST00000358170	CD46	chr1	207943707	+	ENST00000367063	CD55	chr1	207497904	+	2315	1144	69	2192	707
ENST00000322918	CD46	chr1	207943707	+	ENST00000367064	CD55	chr1	207497904	+	3270	1054	69	1913	614
ENST00000322918	CD46	chr1	207943707	+	ENST00000367063	CD55	chr1	207497904	+	2225	1054	69	2102	677
ENST00000367047	CD46	chr1	207943707	+	ENST00000367064	CD55	chr1	207497904	+	3171	955	69	1814	581
ENST00000367047	CD46	chr1	207943707	+	ENST00000367063	CD55	chr1	207497904	+	2126	955	69	2003	644
ENST00000357714	CD46	chr1	207943707	+	ENST00000367064	CD55	chr1	207497904	+	3270	1054	69	1913	614
ENST00000357714	CD46	chr1	207943707	+	ENST00000367063	CD55	chr1	207497904	+	2225	1054	69	2102	677

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000367042	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.000127107	0.9998729
ENST00000367042	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.000298275	0.9997017
ENST00000354848	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.000127107	0.9998729
ENST00000354848	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.000298275	0.9997017
ENST00000441839	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.000127107	0.9998729
ENST00000441839	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.000298275	0.9997017
ENST00000322875	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.000157844	0.99984217
ENST00000322875	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.00038671	0.99961334
ENST00000367041	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.000127595	0.99987245
ENST00000367041	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.000248004	0.999752
ENST00000358170	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.000157844	0.99984217
ENST00000358170	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.00038671	0.99961334
ENST00000322918	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.000127595	0.99987245
ENST00000322918	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.000248004	0.999752
ENST00000367047	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.000149785	0.99985015
ENST00000367047	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.00051886	0.99948114
ENST00000357714	ENST00000367064	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.000127595	0.99987245
ENST00000357714	ENST00000367063	CD46	chr1	207943707	+	CD55	chr1	207497904	+	0.000248004	0.999752

Top

Fusion Genomic Features for CD46-CD55

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
CD46	chr1	207943707	+	CD55	chr1	207497903	+	0.51106155	0.48893842
CD46	chr1	207943707	+	CD55	chr1	207497903	+	0.51106155	0.48893842

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for CD46-CD55

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:207943707/chr1:207497904)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000322875

302_326

329

400.0

Compositional bias

Note=Ser/Thr-rich

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000358170

302_326

329

973.6666666666666

Compositional bias

Note=Ser/Thr-rich

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000322875

160_225

329

400.0

Domain

Sushi 3

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000322875

226_285

329

400.0

Domain

Sushi 4

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000322875

35_96

329

400.0

Domain

Sushi 1

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000322875

97_159

329

400.0

Domain

Sushi 2

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000322918

160_225

299

350.0

Domain

Sushi 3

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000322918

226_285

299

350.0

Domain

Sushi 4

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000322918

35_96

299

350.0

Domain

Sushi 1

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000322918

97_159

299

350.0

Domain

Sushi 2

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000354848

160_225

314

385.0

Domain

Sushi 3

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000354848

226_285

314

385.0

Domain

Sushi 4

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000354848

35_96

314

385.0

Domain

Sushi 1

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000354848

97_159

314

385.0

Domain

Sushi 2

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000357714

160_225

299

370.0

Domain

Sushi 3

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000357714

226_285

299

370.0

Domain

Sushi 4

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000357714

35_96

299

370.0

Domain

Sushi 1

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000357714

97_159

299

370.0

Domain

Sushi 2

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000358170

160_225

329

973.6666666666666

Domain

Sushi 3

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000358170

226_285

329

973.6666666666666

Domain

Sushi 4

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000358170

35_96

329

973.6666666666666

Domain

Sushi 1

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000358170

97_159

329

973.6666666666666

Domain

Sushi 2

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367041

160_225

299

943.6666666666666

Domain

Sushi 3

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367041

226_285

299

943.6666666666666

Domain

Sushi 4

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367041

35_96

299

943.6666666666666

Domain

Sushi 1

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367041

97_159

299

943.6666666666666

Domain

Sushi 2

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367042

160_225

314

958.6666666666666

Domain

Sushi 3

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367042

226_285

314

958.6666666666666

Domain

Sushi 4

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367042

35_96

314

958.6666666666666

Domain

Sushi 1

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367042

97_159

314

958.6666666666666

Domain

Sushi 2

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367047

160_225

266

337.0

Domain

Sushi 3

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367047

35_96

266

337.0

Domain

Sushi 1

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367047

97_159

266

337.0

Domain

Sushi 2

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000441839

160_225

314

365.0

Domain

Sushi 3

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000441839

226_285

314

365.0

Domain

Sushi 4

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000441839

35_96

314

365.0

Domain

Sushi 1

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000441839

97_159

314

365.0

Domain

Sushi 2

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000314754

287_356

441.0

Compositional bias

Note=Ser/Thr-rich

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000367062

287_356

436.0

Compositional bias

Note=Ser/Thr-rich

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000367064

287_356

382.0

Compositional bias

Note=Ser/Thr-rich

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000367065

287_356

440.0

Compositional bias

Note=Ser/Thr-rich

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000391920

287_356

456.0

Compositional bias

Note=Ser/Thr-rich

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000314754

161_222

441.0

Domain

Sushi 3

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000314754

223_285

441.0

Domain

Sushi 4

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000314754

96_160

441.0

Domain

Sushi 2

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000367062

161_222

436.0

Domain

Sushi 3

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000367062

223_285

436.0

Domain

Sushi 4

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000367062

96_160

436.0

Domain

Sushi 2

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000367064

161_222

382.0

Domain

Sushi 3

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000367064

223_285

382.0

Domain

Sushi 4

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000367064

96_160

382.0

Domain

Sushi 2

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000367065

161_222

440.0

Domain

Sushi 3

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000367065

223_285

440.0

Domain

Sushi 4

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000367065

96_160

440.0

Domain

Sushi 2

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000391920

161_222

456.0

Domain

Sushi 3

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000391920

223_285

456.0

Domain

Sushi 4

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000391920

96_160

456.0

Domain

Sushi 2

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000322918

302_326

299

350.0

Compositional bias

Note=Ser/Thr-rich

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000354848

302_326

314

385.0

Compositional bias

Note=Ser/Thr-rich

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000357714

302_326

299

370.0

Compositional bias

Note=Ser/Thr-rich

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000360212

302_326

356.0

Compositional bias

Note=Ser/Thr-rich

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000361067

302_326

386.0

Compositional bias

Note=Ser/Thr-rich

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367041

302_326

299

943.6666666666666

Compositional bias

Note=Ser/Thr-rich

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367042

302_326

314

958.6666666666666

Compositional bias

Note=Ser/Thr-rich

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367047

302_326

266

337.0

Compositional bias

Note=Ser/Thr-rich

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000441839

302_326

314

365.0

Compositional bias

Note=Ser/Thr-rich

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000480003

302_326

371.0

Compositional bias

Note=Ser/Thr-rich

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000360212

160_225

356.0

Domain

Sushi 3

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000360212

226_285

356.0

Domain

Sushi 4

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000360212

35_96

356.0

Domain

Sushi 1

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000360212

97_159

356.0

Domain

Sushi 2

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000361067

160_225

386.0

Domain

Sushi 3

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000361067

226_285

386.0

Domain

Sushi 4

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000361067

35_96

386.0

Domain

Sushi 1

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000361067

97_159

386.0

Domain

Sushi 2

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367047

226_285

266

337.0

Domain

Sushi 4

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000480003

160_225

371.0

Domain

Sushi 3

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000480003

226_285

371.0

Domain

Sushi 4

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000480003

35_96

371.0

Domain

Sushi 1

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000480003

97_159

371.0

Domain

Sushi 2

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000322875

35_343

329

400.0

Topological domain

Extracellular

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000322875

367_392

329

400.0

Topological domain

Cytoplasmic

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000322918

35_343

299

350.0

Topological domain

Extracellular

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000322918

367_392

299

350.0

Topological domain

Cytoplasmic

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000354848

35_343

314

385.0

Topological domain

Extracellular

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000354848

367_392

314

385.0

Topological domain

Cytoplasmic

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000357714

35_343

299

370.0

Topological domain

Extracellular

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000357714

367_392

299

370.0

Topological domain

Cytoplasmic

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000358170

35_343

329

973.6666666666666

Topological domain

Extracellular

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000358170

367_392

329

973.6666666666666

Topological domain

Cytoplasmic

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000360212

35_343

356.0

Topological domain

Extracellular

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000360212

367_392

356.0

Topological domain

Cytoplasmic

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000361067

35_343

386.0

Topological domain

Extracellular

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000361067

367_392

386.0

Topological domain

Cytoplasmic

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367041

35_343

299

943.6666666666666

Topological domain

Extracellular

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367041

367_392

299

943.6666666666666

Topological domain

Cytoplasmic

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367042

35_343

314

958.6666666666666

Topological domain

Extracellular

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367042

367_392

314

958.6666666666666

Topological domain

Cytoplasmic

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367047

35_343

266

337.0

Topological domain

Extracellular

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367047

367_392

266

337.0

Topological domain

Cytoplasmic

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000441839

35_343

314

365.0

Topological domain

Extracellular

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000441839

367_392

314

365.0

Topological domain

Cytoplasmic

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000480003

35_343

371.0

Topological domain

Extracellular

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000480003

367_392

371.0

Topological domain

Cytoplasmic

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000322875

344_366

329

400.0

Transmembrane

Helical

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000322918

344_366

299

350.0

Transmembrane

Helical

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000354848

344_366

314

385.0

Transmembrane

Helical

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000357714

344_366

299

370.0

Transmembrane

Helical

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000358170

344_366

329

973.6666666666666

Transmembrane

Helical

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000360212

344_366

356.0

Transmembrane

Helical

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000361067

344_366

386.0

Transmembrane

Helical

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367041

344_366

299

943.6666666666666

Transmembrane

Helical

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367042

344_366

314

958.6666666666666

Transmembrane

Helical

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000367047

344_366

266

337.0

Transmembrane

Helical

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000441839

344_366

314

365.0

Transmembrane

Helical

Hgene

CD46

chr1:207943707

chr1:207497904

ENST00000480003

344_366

371.0

Transmembrane

Helical

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000314754

35_96

441.0

Domain

Sushi 1

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000367062

35_96

436.0

Domain

Sushi 1

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000367064

35_96

382.0

Domain

Sushi 1

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000367065

35_96

440.0

Domain

Sushi 1

Tgene

CD55

chr1:207943707

chr1:207497904

ENST00000391920

35_96

456.0

Domain

Sushi 1

Top

Fusion Gene Sequence for CD46-CD55

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>14528_14528_1_CD46-CD55_CD46_chr1_207943707_ENST00000322875_CD55_chr1_207497904_ENST00000367063_length(transcript)=2315nt_BP=1144nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCA
CCAACATTTGAAGCTATGGAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATAC
TTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACA
TGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAAT
GAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAA
AAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACT
TATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGT
GCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCC
CCAGTTCCAAAGTGTCTTAAAGTGCTGCCTCCATCTAGTACAAAACCTCCAGCTTTGAGTCATTCAGTGTCGACTTCTTCCACTACAAAA
TCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTA
AATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTTCCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGA
AGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTAAAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCT
AATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTAC
AAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTAT
TGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAAT
AAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGA
GGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAG
AAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACC
CCAAATAAAGGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTATCTGGTTCTCGTCCTGTCACCCAGGCTGGTATGCGGTGGTGTGAT
CGTAGCTCACTGCAGTCTCGAACTCCTGGGTTCAAGCGATCCTTCCACTTCAGCCTCCCAAGTAGCTGGTACTACAGGTGTGTGCCACGA
CACCCGGCTAAGTTTTTGAAATTTATTTTTTGTAGAGACAGGATTTTCCTATGTTGCCCAGGCTGGTTTCAAACTCCTGGCCGTAAGCGA
TTTTTCCGGCCTCCCAAAACGTTGCGATTATAAGTGTGAGCCACTGCACCTGGCCCCACATTTTCTTTATCCATTTGTACATTGATGGAC
ACTTAAGATGATTCCATATCTTTGCTATTGTGAATAGTGCTTCAATAAATATGTGAATGCACATA

>14528_14528_1_CD46-CD55_CD46_chr1_207943707_ENST00000322875_CD55_chr1_207497904_ENST00000367063_length(amino acids)=707AA_BP=458
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVD
YKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS
GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISG
FGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTTKSPASSASGPRPTYKPPVSNYPGS
CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATIS
FSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWS
GPPPECRGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGSRPVTQ
AGMRWCDRSSLQSRTPGFKRSFHFSLPSSWYYRCVPRHPAKFLKFIFCRDRIFLCCPGWFQTPGRKRFFRPPKTLRL

--------------------------------------------------------------
>14528_14528_2_CD46-CD55_CD46_chr1_207943707_ENST00000322875_CD55_chr1_207497904_ENST00000367064_length(transcript)=3360nt_BP=1144nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCA
CCAACATTTGAAGCTATGGAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATAC
TTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACA
TGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAAT
GAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAA
AAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACT
TATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGT
GCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCC
CCAGTTCCAAAGTGTCTTAAAGTGCTGCCTCCATCTAGTACAAAACCTCCAGCTTTGAGTCATTCAGTGTCGACTTCTTCCACTACAAAA
TCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTA
AATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTTCCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGA
AGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTAAAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCT
AATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTAC
AAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTAT
TGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAAT
AAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGA
GGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAG
AAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACC
CCAAATAAAGGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTATCTGGGCACACGTGTTTCACGTTGACAGGTTTGCTTGGGACGCTA
GTAACCATGGGCTTGCTGACTTAGCCAAAGAAGAGTTAAGAAGAAAATACACACAAGTATACAGACTGTTCCTAGTTTCTTAGACTTATC
TGCATATTGGATAAAATAAATGCAATTGTGCTCTTCATTTAGGATGCTTTCATTGTCTTTAAGATGTGTTAGGAATGTCAACAGAGCAAG
GAGAAAAAAGGCAGTCCTGGAATCACATTCTTAGCACACCTACACCTCTTGAAAATAGAACAACTTGCAGAATTGAGAGTGATTCCTTTC
CTAAAAGTGTAAGAAAGCATAGAGATTTGTTCGTATTTAGAATGGGATCACGAGGAAAAGAGAAGGAAAGTGATTTTTTTCCACAAGATC
TGTAATGTTATTTCCACTTATAAAGGAAATAAAAAATGAAAAACATTATTTGGATATCAAAAGCAAATAAAAACCCAATTCAGTCTCTTC
TAAGCAAAATTGCTAAAGAGAGATGAACCACATTATAAAGTAATCTTTGGCTGTAAGGCATTTTCATCTTTCCTTCGGGTTGGCAAAATA
TTTTAAAGGTAAAACATGCTGGTGAACCAGGGGTGTTGATGGTGATAAGGGAGGAATATAGAATGAAAGACTGAATCTTCCTTTGTTGCA
CAAATAGAGTTTGGAAAAAGCCTGTGAAAGGTGTCTTCTTTGACTTAATGTCTTTAAAAGTATCCAGAGATACTACAATATTAACATAAG
AAAAGATTATATATTATTTCTGAATCGAGATGTCCATAGTCAAATTTGTAAATCTTATTCTTTTGTAATATTTATTTATATTTATTTATG
ACAGTGAACATTCTGATTTTACATGTAAAACAAGAAAAGTTGAAGAAGATATGTGAAGAAAAATGTATTTTTCCTAAATAGAAATAAATG
ATCCCATTTTTTGGTATCATGTAGTATGTGAAATTTATTCTTAAACGTGACTACTTTATTTCTAAATAAGAAATTCCCTACCTGCTTCCT
ACAAGCAGTTCAGAATGCCATGCCTTGGTTGTCCTAGTGTGAATAATTTTCAGCTACTTTAAAATTATATTGTACTTTCTCAAGCATGTC
ATATCCTTTCCTATTAGAGTATCTATATTACTTGTTACTGATTTACCTGAAGGCAATCTGATTAATTTCTAGGTTTTTACCATATTCTTG
TCATCTTGCCAATTACATTTTAAGTGTTAGACTAGACTAAGATGTACTAGTTGTATAGAATATAACTAGATTTATTATGGCAATGTTTAT
TTTGTCATTTTGCTTCATCTGTTTTGTTGTTGAAGTACTTTAAATTTCATACGTTCATGGCATTTCACTGTAAAGACTTTAATGTGTATT
TCTTAAAATAAAACTTTTTTTCCTCCTTAA

>14528_14528_2_CD46-CD55_CD46_chr1_207943707_ENST00000322875_CD55_chr1_207497904_ENST00000367064_length(amino acids)=644AA_BP=458
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVD
YKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS
GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISG
FGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTTKSPASSASGPRPTYKPPVSNYPGS
CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATIS
FSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWS
GPPPECRGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGHTCFTL
TGLLGTLVTMGLLT

--------------------------------------------------------------
>14528_14528_3_CD46-CD55_CD46_chr1_207943707_ENST00000322918_CD55_chr1_207497904_ENST00000367063_length(transcript)=2225nt_BP=1054nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCA
CCAACATTTGAAGCTATGGAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATAC
TTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACA
TGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAAT
GAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAA
AAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACT
TATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGT
GCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCC
CCAGTTCCAAAGTGTCTTAAAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTA
AATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTTCCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGA
AGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTAAAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCT
AATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTAC
AAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTAT
TGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAAT
AAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGA
GGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAG
AAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACC
CCAAATAAAGGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTATCTGGTTCTCGTCCTGTCACCCAGGCTGGTATGCGGTGGTGTGAT
CGTAGCTCACTGCAGTCTCGAACTCCTGGGTTCAAGCGATCCTTCCACTTCAGCCTCCCAAGTAGCTGGTACTACAGGTGTGTGCCACGA
CACCCGGCTAAGTTTTTGAAATTTATTTTTTGTAGAGACAGGATTTTCCTATGTTGCCCAGGCTGGTTTCAAACTCCTGGCCGTAAGCGA
TTTTTCCGGCCTCCCAAAACGTTGCGATTATAAGTGTGAGCCACTGCACCTGGCCCCACATTTTCTTTATCCATTTGTACATTGATGGAC
ACTTAAGATGATTCCATATCTTTGCTATTGTGAATAGTGCTTCAATAAATATGTGAATGCACATA

>14528_14528_3_CD46-CD55_CD46_chr1_207943707_ENST00000322918_CD55_chr1_207497904_ENST00000367063_length(amino acids)=677AA_BP=428
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVD
YKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS
GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISG
FGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKPPVSNYPGSCEVPTRLNSASLKQPYITQNYFPVGTVVEY
ECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL
PECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTT
EVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGSRPVTQAGMRWCDRSSLQSRTPGFKRSFHFSLPSSW
YYRCVPRHPAKFLKFIFCRDRIFLCCPGWFQTPGRKRFFRPPKTLRL

--------------------------------------------------------------
>14528_14528_4_CD46-CD55_CD46_chr1_207943707_ENST00000322918_CD55_chr1_207497904_ENST00000367064_length(transcript)=3270nt_BP=1054nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCA
CCAACATTTGAAGCTATGGAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATAC
TTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACA
TGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAAT
GAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAA
AAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACT
TATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGT
GCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCC
CCAGTTCCAAAGTGTCTTAAAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTA
AATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTTCCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGA
AGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTAAAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCT
AATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTAC
AAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTAT
TGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAAT
AAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGA
GGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAG
AAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACC
CCAAATAAAGGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTATCTGGGCACACGTGTTTCACGTTGACAGGTTTGCTTGGGACGCTA
GTAACCATGGGCTTGCTGACTTAGCCAAAGAAGAGTTAAGAAGAAAATACACACAAGTATACAGACTGTTCCTAGTTTCTTAGACTTATC
TGCATATTGGATAAAATAAATGCAATTGTGCTCTTCATTTAGGATGCTTTCATTGTCTTTAAGATGTGTTAGGAATGTCAACAGAGCAAG
GAGAAAAAAGGCAGTCCTGGAATCACATTCTTAGCACACCTACACCTCTTGAAAATAGAACAACTTGCAGAATTGAGAGTGATTCCTTTC
CTAAAAGTGTAAGAAAGCATAGAGATTTGTTCGTATTTAGAATGGGATCACGAGGAAAAGAGAAGGAAAGTGATTTTTTTCCACAAGATC
TGTAATGTTATTTCCACTTATAAAGGAAATAAAAAATGAAAAACATTATTTGGATATCAAAAGCAAATAAAAACCCAATTCAGTCTCTTC
TAAGCAAAATTGCTAAAGAGAGATGAACCACATTATAAAGTAATCTTTGGCTGTAAGGCATTTTCATCTTTCCTTCGGGTTGGCAAAATA
TTTTAAAGGTAAAACATGCTGGTGAACCAGGGGTGTTGATGGTGATAAGGGAGGAATATAGAATGAAAGACTGAATCTTCCTTTGTTGCA
CAAATAGAGTTTGGAAAAAGCCTGTGAAAGGTGTCTTCTTTGACTTAATGTCTTTAAAAGTATCCAGAGATACTACAATATTAACATAAG
AAAAGATTATATATTATTTCTGAATCGAGATGTCCATAGTCAAATTTGTAAATCTTATTCTTTTGTAATATTTATTTATATTTATTTATG
ACAGTGAACATTCTGATTTTACATGTAAAACAAGAAAAGTTGAAGAAGATATGTGAAGAAAAATGTATTTTTCCTAAATAGAAATAAATG
ATCCCATTTTTTGGTATCATGTAGTATGTGAAATTTATTCTTAAACGTGACTACTTTATTTCTAAATAAGAAATTCCCTACCTGCTTCCT
ACAAGCAGTTCAGAATGCCATGCCTTGGTTGTCCTAGTGTGAATAATTTTCAGCTACTTTAAAATTATATTGTACTTTCTCAAGCATGTC
ATATCCTTTCCTATTAGAGTATCTATATTACTTGTTACTGATTTACCTGAAGGCAATCTGATTAATTTCTAGGTTTTTACCATATTCTTG
TCATCTTGCCAATTACATTTTAAGTGTTAGACTAGACTAAGATGTACTAGTTGTATAGAATATAACTAGATTTATTATGGCAATGTTTAT
TTTGTCATTTTGCTTCATCTGTTTTGTTGTTGAAGTACTTTAAATTTCATACGTTCATGGCATTTCACTGTAAAGACTTTAATGTGTATT
TCTTAAAATAAAACTTTTTTTCCTCCTTAA

>14528_14528_4_CD46-CD55_CD46_chr1_207943707_ENST00000322918_CD55_chr1_207497904_ENST00000367064_length(amino acids)=614AA_BP=428
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVD
YKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS
GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISG
FGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKPPVSNYPGSCEVPTRLNSASLKQPYITQNYFPVGTVVEY
ECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL
PECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTT
EVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGHTCFTLTGLLGTLVTMGLLT

--------------------------------------------------------------
>14528_14528_5_CD46-CD55_CD46_chr1_207943707_ENST00000354848_CD55_chr1_207497904_ENST00000367063_length(transcript)=2270nt_BP=1099nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCA
CCAACATTTGAAGCTATGGAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATAC
TTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACA
TGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAAT
GAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAA
AAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACT
TATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGT
GCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCC
CCAGTTCCAAAGTGTCTTAAAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCT
CCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTAAATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTT
CCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGAAGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTA
AAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCTAATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGC
ATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTACAAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGC
TCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTATTGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAA
CGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAATAAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTG
AATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGAGGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCT
ACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAGAAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGG
AGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACCCCAAATAAAGGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTA
TCTGGTTCTCGTCCTGTCACCCAGGCTGGTATGCGGTGGTGTGATCGTAGCTCACTGCAGTCTCGAACTCCTGGGTTCAAGCGATCCTTC
CACTTCAGCCTCCCAAGTAGCTGGTACTACAGGTGTGTGCCACGACACCCGGCTAAGTTTTTGAAATTTATTTTTTGTAGAGACAGGATT
TTCCTATGTTGCCCAGGCTGGTTTCAAACTCCTGGCCGTAAGCGATTTTTCCGGCCTCCCAAAACGTTGCGATTATAAGTGTGAGCCACT
GCACCTGGCCCCACATTTTCTTTATCCATTTGTACATTGATGGACACTTAAGATGATTCCATATCTTTGCTATTGTGAATAGTGCTTCAA
TAAATATGTGAATGCACATA

>14528_14528_5_CD46-CD55_CD46_chr1_207943707_ENST00000354848_CD55_chr1_207497904_ENST00000367063_length(amino acids)=692AA_BP=443
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVD
YKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS
GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISG
FGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASGPRPTYKPPVSNYPGSCEVPTRLNSASLKQP
YITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSS
FCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKV
PPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGSRPVTQAGMRWCDRSSLQSRT
PGFKRSFHFSLPSSWYYRCVPRHPAKFLKFIFCRDRIFLCCPGWFQTPGRKRFFRPPKTLRL

--------------------------------------------------------------
>14528_14528_6_CD46-CD55_CD46_chr1_207943707_ENST00000354848_CD55_chr1_207497904_ENST00000367064_length(transcript)=3315nt_BP=1099nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCA
CCAACATTTGAAGCTATGGAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATAC
TTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACA
TGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAAT
GAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAA
AAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACT
TATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGT
GCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCC
CCAGTTCCAAAGTGTCTTAAAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCT
CCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTAAATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTT
CCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGAAGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTA
AAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCTAATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGC
ATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTACAAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGC
TCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTATTGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAA
CGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAATAAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTG
AATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGAGGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCT
ACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAGAAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGG
AGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACCCCAAATAAAGGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTA
TCTGGGCACACGTGTTTCACGTTGACAGGTTTGCTTGGGACGCTAGTAACCATGGGCTTGCTGACTTAGCCAAAGAAGAGTTAAGAAGAA
AATACACACAAGTATACAGACTGTTCCTAGTTTCTTAGACTTATCTGCATATTGGATAAAATAAATGCAATTGTGCTCTTCATTTAGGAT
GCTTTCATTGTCTTTAAGATGTGTTAGGAATGTCAACAGAGCAAGGAGAAAAAAGGCAGTCCTGGAATCACATTCTTAGCACACCTACAC
CTCTTGAAAATAGAACAACTTGCAGAATTGAGAGTGATTCCTTTCCTAAAAGTGTAAGAAAGCATAGAGATTTGTTCGTATTTAGAATGG
GATCACGAGGAAAAGAGAAGGAAAGTGATTTTTTTCCACAAGATCTGTAATGTTATTTCCACTTATAAAGGAAATAAAAAATGAAAAACA
TTATTTGGATATCAAAAGCAAATAAAAACCCAATTCAGTCTCTTCTAAGCAAAATTGCTAAAGAGAGATGAACCACATTATAAAGTAATC
TTTGGCTGTAAGGCATTTTCATCTTTCCTTCGGGTTGGCAAAATATTTTAAAGGTAAAACATGCTGGTGAACCAGGGGTGTTGATGGTGA
TAAGGGAGGAATATAGAATGAAAGACTGAATCTTCCTTTGTTGCACAAATAGAGTTTGGAAAAAGCCTGTGAAAGGTGTCTTCTTTGACT
TAATGTCTTTAAAAGTATCCAGAGATACTACAATATTAACATAAGAAAAGATTATATATTATTTCTGAATCGAGATGTCCATAGTCAAAT
TTGTAAATCTTATTCTTTTGTAATATTTATTTATATTTATTTATGACAGTGAACATTCTGATTTTACATGTAAAACAAGAAAAGTTGAAG
AAGATATGTGAAGAAAAATGTATTTTTCCTAAATAGAAATAAATGATCCCATTTTTTGGTATCATGTAGTATGTGAAATTTATTCTTAAA
CGTGACTACTTTATTTCTAAATAAGAAATTCCCTACCTGCTTCCTACAAGCAGTTCAGAATGCCATGCCTTGGTTGTCCTAGTGTGAATA
ATTTTCAGCTACTTTAAAATTATATTGTACTTTCTCAAGCATGTCATATCCTTTCCTATTAGAGTATCTATATTACTTGTTACTGATTTA
CCTGAAGGCAATCTGATTAATTTCTAGGTTTTTACCATATTCTTGTCATCTTGCCAATTACATTTTAAGTGTTAGACTAGACTAAGATGT
ACTAGTTGTATAGAATATAACTAGATTTATTATGGCAATGTTTATTTTGTCATTTTGCTTCATCTGTTTTGTTGTTGAAGTACTTTAAAT
TTCATACGTTCATGGCATTTCACTGTAAAGACTTTAATGTGTATTTCTTAAAATAAAACTTTTTTTCCTCCTTAA

>14528_14528_6_CD46-CD55_CD46_chr1_207943707_ENST00000354848_CD55_chr1_207497904_ENST00000367064_length(amino acids)=629AA_BP=443
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVD
YKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS
GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISG
FGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASGPRPTYKPPVSNYPGSCEVPTRLNSASLKQP
YITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSS
FCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKV
PPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGHTCFTLTGLLGTLVTMGLLT

--------------------------------------------------------------
>14528_14528_7_CD46-CD55_CD46_chr1_207943707_ENST00000357714_CD55_chr1_207497904_ENST00000367063_length(transcript)=2225nt_BP=1054nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCA
CCAACATTTGAAGCTATGGAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATAC
TTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACA
TGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAAT
GAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAA
AAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACT
TATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGT
GCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCC
CCAGTTCCAAAGTGTCTTAAAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTA
AATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTTCCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGA
AGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTAAAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCT
AATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTAC
AAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTAT
TGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAAT
AAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGA
GGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAG
AAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACC
CCAAATAAAGGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTATCTGGTTCTCGTCCTGTCACCCAGGCTGGTATGCGGTGGTGTGAT
CGTAGCTCACTGCAGTCTCGAACTCCTGGGTTCAAGCGATCCTTCCACTTCAGCCTCCCAAGTAGCTGGTACTACAGGTGTGTGCCACGA
CACCCGGCTAAGTTTTTGAAATTTATTTTTTGTAGAGACAGGATTTTCCTATGTTGCCCAGGCTGGTTTCAAACTCCTGGCCGTAAGCGA
TTTTTCCGGCCTCCCAAAACGTTGCGATTATAAGTGTGAGCCACTGCACCTGGCCCCACATTTTCTTTATCCATTTGTACATTGATGGAC
ACTTAAGATGATTCCATATCTTTGCTATTGTGAATAGTGCTTCAATAAATATGTGAATGCACATA

>14528_14528_7_CD46-CD55_CD46_chr1_207943707_ENST00000357714_CD55_chr1_207497904_ENST00000367063_length(amino acids)=677AA_BP=428
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVD
YKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS
GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISG
FGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKPPVSNYPGSCEVPTRLNSASLKQPYITQNYFPVGTVVEY
ECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL
PECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTT
EVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGSRPVTQAGMRWCDRSSLQSRTPGFKRSFHFSLPSSW
YYRCVPRHPAKFLKFIFCRDRIFLCCPGWFQTPGRKRFFRPPKTLRL

--------------------------------------------------------------
>14528_14528_8_CD46-CD55_CD46_chr1_207943707_ENST00000357714_CD55_chr1_207497904_ENST00000367064_length(transcript)=3270nt_BP=1054nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCA
CCAACATTTGAAGCTATGGAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATAC
TTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACA
TGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAAT
GAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAA
AAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACT
TATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGT
GCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCC
CCAGTTCCAAAGTGTCTTAAAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTA
AATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTTCCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGA
AGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTAAAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCT
AATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTAC
AAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTAT
TGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAAT
AAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGA
GGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAG
AAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACC
CCAAATAAAGGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTATCTGGGCACACGTGTTTCACGTTGACAGGTTTGCTTGGGACGCTA
GTAACCATGGGCTTGCTGACTTAGCCAAAGAAGAGTTAAGAAGAAAATACACACAAGTATACAGACTGTTCCTAGTTTCTTAGACTTATC
TGCATATTGGATAAAATAAATGCAATTGTGCTCTTCATTTAGGATGCTTTCATTGTCTTTAAGATGTGTTAGGAATGTCAACAGAGCAAG
GAGAAAAAAGGCAGTCCTGGAATCACATTCTTAGCACACCTACACCTCTTGAAAATAGAACAACTTGCAGAATTGAGAGTGATTCCTTTC
CTAAAAGTGTAAGAAAGCATAGAGATTTGTTCGTATTTAGAATGGGATCACGAGGAAAAGAGAAGGAAAGTGATTTTTTTCCACAAGATC
TGTAATGTTATTTCCACTTATAAAGGAAATAAAAAATGAAAAACATTATTTGGATATCAAAAGCAAATAAAAACCCAATTCAGTCTCTTC
TAAGCAAAATTGCTAAAGAGAGATGAACCACATTATAAAGTAATCTTTGGCTGTAAGGCATTTTCATCTTTCCTTCGGGTTGGCAAAATA
TTTTAAAGGTAAAACATGCTGGTGAACCAGGGGTGTTGATGGTGATAAGGGAGGAATATAGAATGAAAGACTGAATCTTCCTTTGTTGCA
CAAATAGAGTTTGGAAAAAGCCTGTGAAAGGTGTCTTCTTTGACTTAATGTCTTTAAAAGTATCCAGAGATACTACAATATTAACATAAG
AAAAGATTATATATTATTTCTGAATCGAGATGTCCATAGTCAAATTTGTAAATCTTATTCTTTTGTAATATTTATTTATATTTATTTATG
ACAGTGAACATTCTGATTTTACATGTAAAACAAGAAAAGTTGAAGAAGATATGTGAAGAAAAATGTATTTTTCCTAAATAGAAATAAATG
ATCCCATTTTTTGGTATCATGTAGTATGTGAAATTTATTCTTAAACGTGACTACTTTATTTCTAAATAAGAAATTCCCTACCTGCTTCCT
ACAAGCAGTTCAGAATGCCATGCCTTGGTTGTCCTAGTGTGAATAATTTTCAGCTACTTTAAAATTATATTGTACTTTCTCAAGCATGTC
ATATCCTTTCCTATTAGAGTATCTATATTACTTGTTACTGATTTACCTGAAGGCAATCTGATTAATTTCTAGGTTTTTACCATATTCTTG
TCATCTTGCCAATTACATTTTAAGTGTTAGACTAGACTAAGATGTACTAGTTGTATAGAATATAACTAGATTTATTATGGCAATGTTTAT
TTTGTCATTTTGCTTCATCTGTTTTGTTGTTGAAGTACTTTAAATTTCATACGTTCATGGCATTTCACTGTAAAGACTTTAATGTGTATT
TCTTAAAATAAAACTTTTTTTCCTCCTTAA

>14528_14528_8_CD46-CD55_CD46_chr1_207943707_ENST00000357714_CD55_chr1_207497904_ENST00000367064_length(amino acids)=614AA_BP=428
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVD
YKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS
GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISG
FGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKPPVSNYPGSCEVPTRLNSASLKQPYITQNYFPVGTVVEY
ECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL
PECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTT
EVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGHTCFTLTGLLGTLVTMGLLT

--------------------------------------------------------------
>14528_14528_9_CD46-CD55_CD46_chr1_207943707_ENST00000358170_CD55_chr1_207497904_ENST00000367063_length(transcript)=2315nt_BP=1144nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCA
CCAACATTTGAAGCTATGGAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATAC
TTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACA
TGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAAT
GAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAA
AAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACT
TATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGT
GCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCC
CCAGTTCCAAAGTGTCTTAAAGTGCTGCCTCCATCTAGTACAAAACCTCCAGCTTTGAGTCATTCAGTGTCGACTTCTTCCACTACAAAA
TCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTA
AATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTTCCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGA
AGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTAAAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCT
AATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTAC
AAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTAT
TGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAAT
AAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGA
GGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAG
AAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACC
CCAAATAAAGGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTATCTGGTTCTCGTCCTGTCACCCAGGCTGGTATGCGGTGGTGTGAT
CGTAGCTCACTGCAGTCTCGAACTCCTGGGTTCAAGCGATCCTTCCACTTCAGCCTCCCAAGTAGCTGGTACTACAGGTGTGTGCCACGA
CACCCGGCTAAGTTTTTGAAATTTATTTTTTGTAGAGACAGGATTTTCCTATGTTGCCCAGGCTGGTTTCAAACTCCTGGCCGTAAGCGA
TTTTTCCGGCCTCCCAAAACGTTGCGATTATAAGTGTGAGCCACTGCACCTGGCCCCACATTTTCTTTATCCATTTGTACATTGATGGAC
ACTTAAGATGATTCCATATCTTTGCTATTGTGAATAGTGCTTCAATAAATATGTGAATGCACATA

>14528_14528_9_CD46-CD55_CD46_chr1_207943707_ENST00000358170_CD55_chr1_207497904_ENST00000367063_length(amino acids)=707AA_BP=458
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVD
YKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS
GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISG
FGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTTKSPASSASGPRPTYKPPVSNYPGS
CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATIS
FSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWS
GPPPECRGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGSRPVTQ
AGMRWCDRSSLQSRTPGFKRSFHFSLPSSWYYRCVPRHPAKFLKFIFCRDRIFLCCPGWFQTPGRKRFFRPPKTLRL

--------------------------------------------------------------
>14528_14528_10_CD46-CD55_CD46_chr1_207943707_ENST00000358170_CD55_chr1_207497904_ENST00000367064_length(transcript)=3360nt_BP=1144nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCA
CCAACATTTGAAGCTATGGAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATAC
TTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACA
TGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAAT
GAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAA
AAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACT
TATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGT
GCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCC
CCAGTTCCAAAGTGTCTTAAAGTGCTGCCTCCATCTAGTACAAAACCTCCAGCTTTGAGTCATTCAGTGTCGACTTCTTCCACTACAAAA
TCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTA
AATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTTCCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGA
AGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTAAAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCT
AATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTAC
AAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTAT
TGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAAT
AAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGA
GGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAG
AAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACC
CCAAATAAAGGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTATCTGGGCACACGTGTTTCACGTTGACAGGTTTGCTTGGGACGCTA
GTAACCATGGGCTTGCTGACTTAGCCAAAGAAGAGTTAAGAAGAAAATACACACAAGTATACAGACTGTTCCTAGTTTCTTAGACTTATC
TGCATATTGGATAAAATAAATGCAATTGTGCTCTTCATTTAGGATGCTTTCATTGTCTTTAAGATGTGTTAGGAATGTCAACAGAGCAAG
GAGAAAAAAGGCAGTCCTGGAATCACATTCTTAGCACACCTACACCTCTTGAAAATAGAACAACTTGCAGAATTGAGAGTGATTCCTTTC
CTAAAAGTGTAAGAAAGCATAGAGATTTGTTCGTATTTAGAATGGGATCACGAGGAAAAGAGAAGGAAAGTGATTTTTTTCCACAAGATC
TGTAATGTTATTTCCACTTATAAAGGAAATAAAAAATGAAAAACATTATTTGGATATCAAAAGCAAATAAAAACCCAATTCAGTCTCTTC
TAAGCAAAATTGCTAAAGAGAGATGAACCACATTATAAAGTAATCTTTGGCTGTAAGGCATTTTCATCTTTCCTTCGGGTTGGCAAAATA
TTTTAAAGGTAAAACATGCTGGTGAACCAGGGGTGTTGATGGTGATAAGGGAGGAATATAGAATGAAAGACTGAATCTTCCTTTGTTGCA
CAAATAGAGTTTGGAAAAAGCCTGTGAAAGGTGTCTTCTTTGACTTAATGTCTTTAAAAGTATCCAGAGATACTACAATATTAACATAAG
AAAAGATTATATATTATTTCTGAATCGAGATGTCCATAGTCAAATTTGTAAATCTTATTCTTTTGTAATATTTATTTATATTTATTTATG
ACAGTGAACATTCTGATTTTACATGTAAAACAAGAAAAGTTGAAGAAGATATGTGAAGAAAAATGTATTTTTCCTAAATAGAAATAAATG
ATCCCATTTTTTGGTATCATGTAGTATGTGAAATTTATTCTTAAACGTGACTACTTTATTTCTAAATAAGAAATTCCCTACCTGCTTCCT
ACAAGCAGTTCAGAATGCCATGCCTTGGTTGTCCTAGTGTGAATAATTTTCAGCTACTTTAAAATTATATTGTACTTTCTCAAGCATGTC
ATATCCTTTCCTATTAGAGTATCTATATTACTTGTTACTGATTTACCTGAAGGCAATCTGATTAATTTCTAGGTTTTTACCATATTCTTG
TCATCTTGCCAATTACATTTTAAGTGTTAGACTAGACTAAGATGTACTAGTTGTATAGAATATAACTAGATTTATTATGGCAATGTTTAT
TTTGTCATTTTGCTTCATCTGTTTTGTTGTTGAAGTACTTTAAATTTCATACGTTCATGGCATTTCACTGTAAAGACTTTAATGTGTATT
TCTTAAAATAAAACTTTTTTTCCTCCTTAA

>14528_14528_10_CD46-CD55_CD46_chr1_207943707_ENST00000358170_CD55_chr1_207497904_ENST00000367064_length(amino acids)=644AA_BP=458
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVD
YKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS
GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISG
FGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTTKSPASSASGPRPTYKPPVSNYPGS
CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATIS
FSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWS
GPPPECRGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGHTCFTL
TGLLGTLVTMGLLT

--------------------------------------------------------------
>14528_14528_11_CD46-CD55_CD46_chr1_207943707_ENST00000367041_CD55_chr1_207497904_ENST00000367063_length(transcript)=2225nt_BP=1054nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCA
CCAACATTTGAAGCTATGGAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATAC
TTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACA
TGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAAT
GAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAA
AAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACT
TATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGT
GCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCC
CCAGTTCCAAAGTGTCTTAAAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTA
AATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTTCCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGA
AGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTAAAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCT
AATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTAC
AAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTAT
TGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAAT
AAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGA
GGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAG
AAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACC
CCAAATAAAGGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTATCTGGTTCTCGTCCTGTCACCCAGGCTGGTATGCGGTGGTGTGAT
CGTAGCTCACTGCAGTCTCGAACTCCTGGGTTCAAGCGATCCTTCCACTTCAGCCTCCCAAGTAGCTGGTACTACAGGTGTGTGCCACGA
CACCCGGCTAAGTTTTTGAAATTTATTTTTTGTAGAGACAGGATTTTCCTATGTTGCCCAGGCTGGTTTCAAACTCCTGGCCGTAAGCGA
TTTTTCCGGCCTCCCAAAACGTTGCGATTATAAGTGTGAGCCACTGCACCTGGCCCCACATTTTCTTTATCCATTTGTACATTGATGGAC
ACTTAAGATGATTCCATATCTTTGCTATTGTGAATAGTGCTTCAATAAATATGTGAATGCACATA

>14528_14528_11_CD46-CD55_CD46_chr1_207943707_ENST00000367041_CD55_chr1_207497904_ENST00000367063_length(amino acids)=677AA_BP=428
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVD
YKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS
GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISG
FGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKPPVSNYPGSCEVPTRLNSASLKQPYITQNYFPVGTVVEY
ECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL
PECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTT
EVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGSRPVTQAGMRWCDRSSLQSRTPGFKRSFHFSLPSSW
YYRCVPRHPAKFLKFIFCRDRIFLCCPGWFQTPGRKRFFRPPKTLRL

--------------------------------------------------------------
>14528_14528_12_CD46-CD55_CD46_chr1_207943707_ENST00000367041_CD55_chr1_207497904_ENST00000367064_length(transcript)=3270nt_BP=1054nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCA
CCAACATTTGAAGCTATGGAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATAC
TTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACA
TGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAAT
GAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAA
AAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACT
TATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGT
GCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCC
CCAGTTCCAAAGTGTCTTAAAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTA
AATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTTCCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGA
AGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTAAAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCT
AATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTAC
AAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTAT
TGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAAT
AAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGA
GGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAG
AAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACC
CCAAATAAAGGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTATCTGGGCACACGTGTTTCACGTTGACAGGTTTGCTTGGGACGCTA
GTAACCATGGGCTTGCTGACTTAGCCAAAGAAGAGTTAAGAAGAAAATACACACAAGTATACAGACTGTTCCTAGTTTCTTAGACTTATC
TGCATATTGGATAAAATAAATGCAATTGTGCTCTTCATTTAGGATGCTTTCATTGTCTTTAAGATGTGTTAGGAATGTCAACAGAGCAAG
GAGAAAAAAGGCAGTCCTGGAATCACATTCTTAGCACACCTACACCTCTTGAAAATAGAACAACTTGCAGAATTGAGAGTGATTCCTTTC
CTAAAAGTGTAAGAAAGCATAGAGATTTGTTCGTATTTAGAATGGGATCACGAGGAAAAGAGAAGGAAAGTGATTTTTTTCCACAAGATC
TGTAATGTTATTTCCACTTATAAAGGAAATAAAAAATGAAAAACATTATTTGGATATCAAAAGCAAATAAAAACCCAATTCAGTCTCTTC
TAAGCAAAATTGCTAAAGAGAGATGAACCACATTATAAAGTAATCTTTGGCTGTAAGGCATTTTCATCTTTCCTTCGGGTTGGCAAAATA
TTTTAAAGGTAAAACATGCTGGTGAACCAGGGGTGTTGATGGTGATAAGGGAGGAATATAGAATGAAAGACTGAATCTTCCTTTGTTGCA
CAAATAGAGTTTGGAAAAAGCCTGTGAAAGGTGTCTTCTTTGACTTAATGTCTTTAAAAGTATCCAGAGATACTACAATATTAACATAAG
AAAAGATTATATATTATTTCTGAATCGAGATGTCCATAGTCAAATTTGTAAATCTTATTCTTTTGTAATATTTATTTATATTTATTTATG
ACAGTGAACATTCTGATTTTACATGTAAAACAAGAAAAGTTGAAGAAGATATGTGAAGAAAAATGTATTTTTCCTAAATAGAAATAAATG
ATCCCATTTTTTGGTATCATGTAGTATGTGAAATTTATTCTTAAACGTGACTACTTTATTTCTAAATAAGAAATTCCCTACCTGCTTCCT
ACAAGCAGTTCAGAATGCCATGCCTTGGTTGTCCTAGTGTGAATAATTTTCAGCTACTTTAAAATTATATTGTACTTTCTCAAGCATGTC
ATATCCTTTCCTATTAGAGTATCTATATTACTTGTTACTGATTTACCTGAAGGCAATCTGATTAATTTCTAGGTTTTTACCATATTCTTG
TCATCTTGCCAATTACATTTTAAGTGTTAGACTAGACTAAGATGTACTAGTTGTATAGAATATAACTAGATTTATTATGGCAATGTTTAT
TTTGTCATTTTGCTTCATCTGTTTTGTTGTTGAAGTACTTTAAATTTCATACGTTCATGGCATTTCACTGTAAAGACTTTAATGTGTATT
TCTTAAAATAAAACTTTTTTTCCTCCTTAA

>14528_14528_12_CD46-CD55_CD46_chr1_207943707_ENST00000367041_CD55_chr1_207497904_ENST00000367064_length(amino acids)=614AA_BP=428
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVD
YKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS
GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISG
FGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKPPVSNYPGSCEVPTRLNSASLKQPYITQNYFPVGTVVEY
ECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL
PECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTT
EVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGHTCFTLTGLLGTLVTMGLLT

--------------------------------------------------------------
>14528_14528_13_CD46-CD55_CD46_chr1_207943707_ENST00000367042_CD55_chr1_207497904_ENST00000367063_length(transcript)=2270nt_BP=1099nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCA
CCAACATTTGAAGCTATGGAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATAC
TTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACA
TGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAAT
GAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAA
AAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACT
TATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGT
GCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCC
CCAGTTCCAAAGTGTCTTAAAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCT
CCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTAAATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTT
CCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGAAGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTA
AAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCTAATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGC
ATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTACAAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGC
TCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTATTGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAA
CGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAATAAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTG
AATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGAGGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCT
ACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAGAAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGG
AGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACCCCAAATAAAGGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTA
TCTGGTTCTCGTCCTGTCACCCAGGCTGGTATGCGGTGGTGTGATCGTAGCTCACTGCAGTCTCGAACTCCTGGGTTCAAGCGATCCTTC
CACTTCAGCCTCCCAAGTAGCTGGTACTACAGGTGTGTGCCACGACACCCGGCTAAGTTTTTGAAATTTATTTTTTGTAGAGACAGGATT
TTCCTATGTTGCCCAGGCTGGTTTCAAACTCCTGGCCGTAAGCGATTTTTCCGGCCTCCCAAAACGTTGCGATTATAAGTGTGAGCCACT
GCACCTGGCCCCACATTTTCTTTATCCATTTGTACATTGATGGACACTTAAGATGATTCCATATCTTTGCTATTGTGAATAGTGCTTCAA
TAAATATGTGAATGCACATA

>14528_14528_13_CD46-CD55_CD46_chr1_207943707_ENST00000367042_CD55_chr1_207497904_ENST00000367063_length(amino acids)=692AA_BP=443
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVD
YKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS
GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISG
FGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASGPRPTYKPPVSNYPGSCEVPTRLNSASLKQP
YITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSS
FCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKV
PPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGSRPVTQAGMRWCDRSSLQSRT
PGFKRSFHFSLPSSWYYRCVPRHPAKFLKFIFCRDRIFLCCPGWFQTPGRKRFFRPPKTLRL

--------------------------------------------------------------
>14528_14528_14_CD46-CD55_CD46_chr1_207943707_ENST00000367042_CD55_chr1_207497904_ENST00000367064_length(transcript)=3315nt_BP=1099nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCA
CCAACATTTGAAGCTATGGAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATAC
TTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACA
TGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAAT
GAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAA
AAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACT
TATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGT
GCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCC
CCAGTTCCAAAGTGTCTTAAAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCT
CCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTAAATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTT
CCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGAAGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTA
AAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCTAATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGC
ATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTACAAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGC
TCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTATTGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAA
CGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAATAAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTG
AATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGAGGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCT
ACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAGAAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGG
AGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACCCCAAATAAAGGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTA
TCTGGGCACACGTGTTTCACGTTGACAGGTTTGCTTGGGACGCTAGTAACCATGGGCTTGCTGACTTAGCCAAAGAAGAGTTAAGAAGAA
AATACACACAAGTATACAGACTGTTCCTAGTTTCTTAGACTTATCTGCATATTGGATAAAATAAATGCAATTGTGCTCTTCATTTAGGAT
GCTTTCATTGTCTTTAAGATGTGTTAGGAATGTCAACAGAGCAAGGAGAAAAAAGGCAGTCCTGGAATCACATTCTTAGCACACCTACAC
CTCTTGAAAATAGAACAACTTGCAGAATTGAGAGTGATTCCTTTCCTAAAAGTGTAAGAAAGCATAGAGATTTGTTCGTATTTAGAATGG
GATCACGAGGAAAAGAGAAGGAAAGTGATTTTTTTCCACAAGATCTGTAATGTTATTTCCACTTATAAAGGAAATAAAAAATGAAAAACA
TTATTTGGATATCAAAAGCAAATAAAAACCCAATTCAGTCTCTTCTAAGCAAAATTGCTAAAGAGAGATGAACCACATTATAAAGTAATC
TTTGGCTGTAAGGCATTTTCATCTTTCCTTCGGGTTGGCAAAATATTTTAAAGGTAAAACATGCTGGTGAACCAGGGGTGTTGATGGTGA
TAAGGGAGGAATATAGAATGAAAGACTGAATCTTCCTTTGTTGCACAAATAGAGTTTGGAAAAAGCCTGTGAAAGGTGTCTTCTTTGACT
TAATGTCTTTAAAAGTATCCAGAGATACTACAATATTAACATAAGAAAAGATTATATATTATTTCTGAATCGAGATGTCCATAGTCAAAT
TTGTAAATCTTATTCTTTTGTAATATTTATTTATATTTATTTATGACAGTGAACATTCTGATTTTACATGTAAAACAAGAAAAGTTGAAG
AAGATATGTGAAGAAAAATGTATTTTTCCTAAATAGAAATAAATGATCCCATTTTTTGGTATCATGTAGTATGTGAAATTTATTCTTAAA
CGTGACTACTTTATTTCTAAATAAGAAATTCCCTACCTGCTTCCTACAAGCAGTTCAGAATGCCATGCCTTGGTTGTCCTAGTGTGAATA
ATTTTCAGCTACTTTAAAATTATATTGTACTTTCTCAAGCATGTCATATCCTTTCCTATTAGAGTATCTATATTACTTGTTACTGATTTA
CCTGAAGGCAATCTGATTAATTTCTAGGTTTTTACCATATTCTTGTCATCTTGCCAATTACATTTTAAGTGTTAGACTAGACTAAGATGT
ACTAGTTGTATAGAATATAACTAGATTTATTATGGCAATGTTTATTTTGTCATTTTGCTTCATCTGTTTTGTTGTTGAAGTACTTTAAAT
TTCATACGTTCATGGCATTTCACTGTAAAGACTTTAATGTGTATTTCTTAAAATAAAACTTTTTTTCCTCCTTAA

>14528_14528_14_CD46-CD55_CD46_chr1_207943707_ENST00000367042_CD55_chr1_207497904_ENST00000367064_length(amino acids)=629AA_BP=443
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVD
YKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS
GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISG
FGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASGPRPTYKPPVSNYPGSCEVPTRLNSASLKQP
YITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSS
FCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKV
PPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGHTCFTLTGLLGTLVTMGLLT

--------------------------------------------------------------
>14528_14528_15_CD46-CD55_CD46_chr1_207943707_ENST00000367047_CD55_chr1_207497904_ENST00000367063_length(transcript)=2126nt_BP=955nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGGAGAAACATGTCCATAT
ATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGAGGGTTAT
TACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAAAAGGTTTTG
TGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACTTATAGTTGT
GATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGTGCTGCTCCA
GAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTACAAAGCAACA
GTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCA
AAGTGTCTTAAAGTGCTGCCTCCATCTAGTACAAAACCTCCAGCTTTGAGTCATTCAGTGTCGACTTCTTCCACTACAAAATCTCCAGCG
TCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTAAATTCTGCA
TCCCTCAAACAGCCTTATATCACTCAGAATTATTTTCCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGAAGAGAACCT
TCTCTATCACCAAAACTAACTTGCCTTCAGAATTTAAAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCTAATCCGGGA
GAAATACGAAATGGTCAGATTGATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTACAAATTATTT
GGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTATTGTCCAGCA
CCACCACAAATTGACAATGGAATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAATAAAGGATTC
ACCATGATTGGAGAGCACTCTATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGAGGAAAATCT
CTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAGAAAACCACC
ACAAAAACCACCACACCAAATGCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACCCCAAATAAA
GGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTATCTGGTTCTCGTCCTGTCACCCAGGCTGGTATGCGGTGGTGTGATCGTAGCTCA
CTGCAGTCTCGAACTCCTGGGTTCAAGCGATCCTTCCACTTCAGCCTCCCAAGTAGCTGGTACTACAGGTGTGTGCCACGACACCCGGCT
AAGTTTTTGAAATTTATTTTTTGTAGAGACAGGATTTTCCTATGTTGCCCAGGCTGGTTTCAAACTCCTGGCCGTAAGCGATTTTTCCGG
CCTCCCAAAACGTTGCGATTATAAGTGTGAGCCACTGCACCTGGCCCCACATTTTCTTTATCCATTTGTACATTGATGGACACTTAAGAT
GATTCCATATCTTTGCTATTGTGAATAGTGCTTCAATAAATATGTGAATGCACATA

>14528_14528_15_CD46-CD55_CD46_chr1_207943707_ENST00000367047_CD55_chr1_207497904_ENST00000367063_length(amino acids)=644AA_BP=395
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSGETCPYIRDPLNGQAVPANGTYEFGYQMH
FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNS
VWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTS
STTKSPASSASGPRPTYKPPVSNYPGSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKK
KSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVT
YACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHF
HETTPNKGSGTTSGTTRLLSGSRPVTQAGMRWCDRSSLQSRTPGFKRSFHFSLPSSWYYRCVPRHPAKFLKFIFCRDRIFLCCPGWFQTP
GRKRFFRPPKTLRL

--------------------------------------------------------------
>14528_14528_16_CD46-CD55_CD46_chr1_207943707_ENST00000367047_CD55_chr1_207497904_ENST00000367064_length(transcript)=3171nt_BP=955nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGGAGAAACATGTCCATAT
ATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGAGGGTTAT
TACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAAAAGGTTTTG
TGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACTTATAGTTGT
GATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGTGCTGCTCCA
GAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTACAAAGCAACA
GTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCA
AAGTGTCTTAAAGTGCTGCCTCCATCTAGTACAAAACCTCCAGCTTTGAGTCATTCAGTGTCGACTTCTTCCACTACAAAATCTCCAGCG
TCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTAAATTCTGCA
TCCCTCAAACAGCCTTATATCACTCAGAATTATTTTCCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGAAGAGAACCT
TCTCTATCACCAAAACTAACTTGCCTTCAGAATTTAAAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCTAATCCGGGA
GAAATACGAAATGGTCAGATTGATGTACCAGGTGGCATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTACAAATTATTT
GGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGCTCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTATTGTCCAGCA
CCACCACAAATTGACAATGGAATAATTCAAGGGGAACGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAATAAAGGATTC
ACCATGATTGGAGAGCACTCTATTTATTGTACTGTGAATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGAGGAAAATCT
CTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCTACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAGAAAACCACC
ACAAAAACCACCACACCAAATGCTCAAGCAACACGGAGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACCCCAAATAAA
GGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTATCTGGGCACACGTGTTTCACGTTGACAGGTTTGCTTGGGACGCTAGTAACCATG
GGCTTGCTGACTTAGCCAAAGAAGAGTTAAGAAGAAAATACACACAAGTATACAGACTGTTCCTAGTTTCTTAGACTTATCTGCATATTG
GATAAAATAAATGCAATTGTGCTCTTCATTTAGGATGCTTTCATTGTCTTTAAGATGTGTTAGGAATGTCAACAGAGCAAGGAGAAAAAA
GGCAGTCCTGGAATCACATTCTTAGCACACCTACACCTCTTGAAAATAGAACAACTTGCAGAATTGAGAGTGATTCCTTTCCTAAAAGTG
TAAGAAAGCATAGAGATTTGTTCGTATTTAGAATGGGATCACGAGGAAAAGAGAAGGAAAGTGATTTTTTTCCACAAGATCTGTAATGTT
ATTTCCACTTATAAAGGAAATAAAAAATGAAAAACATTATTTGGATATCAAAAGCAAATAAAAACCCAATTCAGTCTCTTCTAAGCAAAA
TTGCTAAAGAGAGATGAACCACATTATAAAGTAATCTTTGGCTGTAAGGCATTTTCATCTTTCCTTCGGGTTGGCAAAATATTTTAAAGG
TAAAACATGCTGGTGAACCAGGGGTGTTGATGGTGATAAGGGAGGAATATAGAATGAAAGACTGAATCTTCCTTTGTTGCACAAATAGAG
TTTGGAAAAAGCCTGTGAAAGGTGTCTTCTTTGACTTAATGTCTTTAAAAGTATCCAGAGATACTACAATATTAACATAAGAAAAGATTA
TATATTATTTCTGAATCGAGATGTCCATAGTCAAATTTGTAAATCTTATTCTTTTGTAATATTTATTTATATTTATTTATGACAGTGAAC
ATTCTGATTTTACATGTAAAACAAGAAAAGTTGAAGAAGATATGTGAAGAAAAATGTATTTTTCCTAAATAGAAATAAATGATCCCATTT
TTTGGTATCATGTAGTATGTGAAATTTATTCTTAAACGTGACTACTTTATTTCTAAATAAGAAATTCCCTACCTGCTTCCTACAAGCAGT
TCAGAATGCCATGCCTTGGTTGTCCTAGTGTGAATAATTTTCAGCTACTTTAAAATTATATTGTACTTTCTCAAGCATGTCATATCCTTT
CCTATTAGAGTATCTATATTACTTGTTACTGATTTACCTGAAGGCAATCTGATTAATTTCTAGGTTTTTACCATATTCTTGTCATCTTGC
CAATTACATTTTAAGTGTTAGACTAGACTAAGATGTACTAGTTGTATAGAATATAACTAGATTTATTATGGCAATGTTTATTTTGTCATT
TTGCTTCATCTGTTTTGTTGTTGAAGTACTTTAAATTTCATACGTTCATGGCATTTCACTGTAAAGACTTTAATGTGTATTTCTTAAAAT
AAAACTTTTTTTCCTCCTTAA

>14528_14528_16_CD46-CD55_CD46_chr1_207943707_ENST00000367047_CD55_chr1_207497904_ENST00000367064_length(amino acids)=581AA_BP=395
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSGETCPYIRDPLNGQAVPANGTYEFGYQMH
FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNS
VWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTS
STTKSPASSASGPRPTYKPPVSNYPGSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKK
KSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVT
YACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHF
HETTPNKGSGTTSGTTRLLSGHTCFTLTGLLGTLVTMGLLT

--------------------------------------------------------------
>14528_14528_17_CD46-CD55_CD46_chr1_207943707_ENST00000441839_CD55_chr1_207497904_ENST00000367063_length(transcript)=2270nt_BP=1099nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCA
CCAACATTTGAAGCTATGGAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATAC
TTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACA
TGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAAT
GAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAA
AAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACT
TATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGT
GCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCC
CCAGTTCCAAAGTGTCTTAAAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCT
CCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTAAATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTT
CCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGAAGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTA
AAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCTAATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGC
ATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTACAAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGC
TCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTATTGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAA
CGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAATAAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTG
AATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGAGGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCT
ACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAGAAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGG
AGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACCCCAAATAAAGGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTA
TCTGGTTCTCGTCCTGTCACCCAGGCTGGTATGCGGTGGTGTGATCGTAGCTCACTGCAGTCTCGAACTCCTGGGTTCAAGCGATCCTTC
CACTTCAGCCTCCCAAGTAGCTGGTACTACAGGTGTGTGCCACGACACCCGGCTAAGTTTTTGAAATTTATTTTTTGTAGAGACAGGATT
TTCCTATGTTGCCCAGGCTGGTTTCAAACTCCTGGCCGTAAGCGATTTTTCCGGCCTCCCAAAACGTTGCGATTATAAGTGTGAGCCACT
GCACCTGGCCCCACATTTTCTTTATCCATTTGTACATTGATGGACACTTAAGATGATTCCATATCTTTGCTATTGTGAATAGTGCTTCAA
TAAATATGTGAATGCACATA

>14528_14528_17_CD46-CD55_CD46_chr1_207943707_ENST00000441839_CD55_chr1_207497904_ENST00000367063_length(amino acids)=692AA_BP=443
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVD
YKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS
GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISG
FGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASGPRPTYKPPVSNYPGSCEVPTRLNSASLKQP
YITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSS
FCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKV
PPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGSRPVTQAGMRWCDRSSLQSRT
PGFKRSFHFSLPSSWYYRCVPRHPAKFLKFIFCRDRIFLCCPGWFQTPGRKRFFRPPKTLRL

--------------------------------------------------------------
>14528_14528_18_CD46-CD55_CD46_chr1_207943707_ENST00000441839_CD55_chr1_207497904_ENST00000367064_length(transcript)=3315nt_BP=1099nt
GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCC
CTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAG
TGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCA
CCAACATTTGAAGCTATGGAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATAC
TTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACA
TGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAAT
GAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAA
AAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACT
TATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGT
GCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCC
CCAGTTCCAAAGTGTCTTAAAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCT
CCAGTCTCAAATTATCCAGGTAGCTGCGAGGTGCCAACAAGGCTAAATTCTGCATCCCTCAAACAGCCTTATATCACTCAGAATTATTTT
CCAGTCGGTACTGTTGTGGAATATGAGTGCCGTCCAGGTTACAGAAGAGAACCTTCTCTATCACCAAAACTAACTTGCCTTCAGAATTTA
AAATGGTCCACAGCAGTCGAATTTTGTAAAAAGAAATCATGCCCTAATCCGGGAGAAATACGAAATGGTCAGATTGATGTACCAGGTGGC
ATATTATTTGGTGCAACCATCTCCTTCTCATGTAACACAGGGTACAAATTATTTGGCTCGACTTCTAGTTTTTGTCTTATTTCAGGCAGC
TCTGTCCAGTGGAGTGACCCGTTGCCAGAGTGCAGAGAAATTTATTGTCCAGCACCACCACAAATTGACAATGGAATAATTCAAGGGGAA
CGTGACCATTATGGATATAGACAGTCTGTAACGTATGCATGTAATAAAGGATTCACCATGATTGGAGAGCACTCTATTTATTGTACTGTG
AATAATGATGAAGGAGAGTGGAGTGGCCCACCACCTGAATGCAGAGGAAAATCTCTAACTTCCAAGGTCCCACCAACAGTTCAGAAACCT
ACCACAGTAAATGTTCCAACTACAGAAGTCTCACCAACTTCTCAGAAAACCACCACAAAAACCACCACACCAAATGCTCAAGCAACACGG
AGTACACCTGTTTCCAGGACAACCAAGCATTTTCATGAAACAACCCCAAATAAAGGAAGTGGAACCACTTCAGGTACTACCCGTCTTCTA
TCTGGGCACACGTGTTTCACGTTGACAGGTTTGCTTGGGACGCTAGTAACCATGGGCTTGCTGACTTAGCCAAAGAAGAGTTAAGAAGAA
AATACACACAAGTATACAGACTGTTCCTAGTTTCTTAGACTTATCTGCATATTGGATAAAATAAATGCAATTGTGCTCTTCATTTAGGAT
GCTTTCATTGTCTTTAAGATGTGTTAGGAATGTCAACAGAGCAAGGAGAAAAAAGGCAGTCCTGGAATCACATTCTTAGCACACCTACAC
CTCTTGAAAATAGAACAACTTGCAGAATTGAGAGTGATTCCTTTCCTAAAAGTGTAAGAAAGCATAGAGATTTGTTCGTATTTAGAATGG
GATCACGAGGAAAAGAGAAGGAAAGTGATTTTTTTCCACAAGATCTGTAATGTTATTTCCACTTATAAAGGAAATAAAAAATGAAAAACA
TTATTTGGATATCAAAAGCAAATAAAAACCCAATTCAGTCTCTTCTAAGCAAAATTGCTAAAGAGAGATGAACCACATTATAAAGTAATC
TTTGGCTGTAAGGCATTTTCATCTTTCCTTCGGGTTGGCAAAATATTTTAAAGGTAAAACATGCTGGTGAACCAGGGGTGTTGATGGTGA
TAAGGGAGGAATATAGAATGAAAGACTGAATCTTCCTTTGTTGCACAAATAGAGTTTGGAAAAAGCCTGTGAAAGGTGTCTTCTTTGACT
TAATGTCTTTAAAAGTATCCAGAGATACTACAATATTAACATAAGAAAAGATTATATATTATTTCTGAATCGAGATGTCCATAGTCAAAT
TTGTAAATCTTATTCTTTTGTAATATTTATTTATATTTATTTATGACAGTGAACATTCTGATTTTACATGTAAAACAAGAAAAGTTGAAG
AAGATATGTGAAGAAAAATGTATTTTTCCTAAATAGAAATAAATGATCCCATTTTTTGGTATCATGTAGTATGTGAAATTTATTCTTAAA
CGTGACTACTTTATTTCTAAATAAGAAATTCCCTACCTGCTTCCTACAAGCAGTTCAGAATGCCATGCCTTGGTTGTCCTAGTGTGAATA
ATTTTCAGCTACTTTAAAATTATATTGTACTTTCTCAAGCATGTCATATCCTTTCCTATTAGAGTATCTATATTACTTGTTACTGATTTA
CCTGAAGGCAATCTGATTAATTTCTAGGTTTTTACCATATTCTTGTCATCTTGCCAATTACATTTTAAGTGTTAGACTAGACTAAGATGT
ACTAGTTGTATAGAATATAACTAGATTTATTATGGCAATGTTTATTTTGTCATTTTGCTTCATCTGTTTTGTTGTTGAAGTACTTTAAAT
TTCATACGTTCATGGCATTTCACTGTAAAGACTTTAATGTGTATTTCTTAAAATAAAACTTTTTTTCCTCCTTAA

>14528_14528_18_CD46-CD55_CD46_chr1_207943707_ENST00000441839_CD55_chr1_207497904_ENST00000367064_length(amino acids)=629AA_BP=443
MDPEGTSLLGWLSVSLLSSGEITASSAPRMEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVD
YKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS
GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISG
FGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASGPRPTYKPPVSNYPGSCEVPTRLNSASLKQP
YITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSS
FCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKV
PPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGHTCFTLTGLLGTLVTMGLLT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CD46-CD55

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for CD46-CD55

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for CD46-CD55

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	CD46	C2752040	HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 2	6	GENOMICS_ENGLAND;UNIPROT
Hgene	CD46	C2931788	Atypical Hemolytic Uremic Syndrome	2	CTD_human;GENOMICS_ENGLAND
Hgene	CD46	C0019061	Hemolytic-Uremic Syndrome	1	GENOMICS_ENGLAND
Hgene	CD46	C0025007	Measles	1	CTD_human
Hgene	CD46	C0162739	HELLP Syndrome	1	ORPHANET
Hgene	CD46	C0272242	Complement deficiency disease	1	GENOMICS_ENGLAND
Hgene	CD46	C3658266	Prostatic Cancer, Castration-Resistant	1	CTD_human
Hgene	CD46	C3658267	Prostatic Neoplasms, Castration-Resistant	1	CTD_human
Hgene	CD46	C4087273	C3 glomerulopathy	1	GENOMICS_ENGLAND
Tgene		C4538570	COMPLEMENT HYPERACTIVATION, ANGIOPATHIC THROMBOSIS, AND PROTEIN-LOSING ENTEROPATHY	2	UNIPROT
Tgene		C0014175	Endometriosis	1	CTD_human
Tgene		C0033680	Protein-Losing Enteropathies	1	CTD_human;GENOMICS_ENGLAND
Tgene		C0086438	Hypogammaglobulinemia	1	GENOMICS_ENGLAND
Tgene		C0236733	Amphetamine-Related Disorders	1	CTD_human
Tgene		C0236804	Amphetamine Addiction	1	CTD_human
Tgene		C0236807	Amphetamine Abuse	1	CTD_human
Tgene		C0267372	Primary intestinal lymphangiectasia	1	GENOMICS_ENGLAND
Tgene		C0269102	Endometrioma	1	CTD_human
Tgene		C0272242	Complement deficiency disease	1	GENOMICS_ENGLAND

Fusion Gene Studies in Kim Lab

Fusion gene:CD46-CD55 (FusionGDB2 ID:HG4179TG1604)

Fusion Gene Summary for CD46-CD55

Fusion Gene ORF analysis for CD46-CD55

Fusion Genomic Features for CD46-CD55

Fusion Protein Features for CD46-CD55

Fusion Gene Sequence for CD46-CD55

Fusion Gene PPI Analysis for CD46-CD55

Related Drugs for CD46-CD55

Related Diseases for CD46-CD55

Fusion Gene Studies
in Kim Lab