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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CSAD-ZYG11B (FusionGDB2 ID:HG51380TG79699)

Fusion Gene Summary for CSAD-ZYG11B

check button Fusion gene summary
Fusion gene informationFusion gene name: CSAD-ZYG11B
Fusion gene ID: hg51380tg79699
HgeneTgene
Gene symbol

CSAD

ZYG11B

Gene ID

51380

79699

Gene namecysteine sulfinic acid decarboxylasezyg-11 family member B, cell cycle regulator
SynonymsCSD|PCAPZYG11
Cytomap('CSAD')('ZYG11B')

12q13.13

1p32.3

Type of geneprotein-codingprotein-coding
Descriptioncysteine sulfinic acid decarboxylaseP-selectin cytoplasmic tail-associated proteinaspartate 1-decarboxylasecysteine sulfinic acid decarboxylase-related proteincysteine-sulfinate decarboxylasesulfinoalanine decarboxylaseprotein zyg-11 homolog Bzyg-11 homolog B
Modification date2020031320200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000379843, ENST00000444623, 
ENST00000267085, ENST00000379846, 
ENST00000453446, ENST00000491654, 
ENST00000542115, 
Fusion gene scores* DoF score8 X 7 X 5=2806 X 12 X 4=288
# samples 812
** MAII scorelog2(8/280*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/288*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CSAD [Title/Abstract] AND ZYG11B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCSAD(53553904)-ZYG11B(53222130), # samples:1
Anticipated loss of major functional domain due to fusion event.CSAD-ZYG11B seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
CSAD-ZYG11B seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CSAD (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ZYG11B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-B6-A0IQ-01ACSADchr12

53553904

-ZYG11Bchr1

53222130

+


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Fusion Gene ORF analysis for CSAD-ZYG11B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000379843ENST00000294353CSADchr12

53553904

-ZYG11Bchr1

53222130

+
Frame-shiftENST00000379843ENST00000443756CSADchr12

53553904

-ZYG11Bchr1

53222130

+
Frame-shiftENST00000379843ENST00000545132CSADchr12

53553904

-ZYG11Bchr1

53222130

+
Frame-shiftENST00000444623ENST00000294353CSADchr12

53553904

-ZYG11Bchr1

53222130

+
Frame-shiftENST00000444623ENST00000443756CSADchr12

53553904

-ZYG11Bchr1

53222130

+
Frame-shiftENST00000444623ENST00000545132CSADchr12

53553904

-ZYG11Bchr1

53222130

+
In-frameENST00000267085ENST00000294353CSADchr12

53553904

-ZYG11Bchr1

53222130

+
In-frameENST00000267085ENST00000443756CSADchr12

53553904

-ZYG11Bchr1

53222130

+
In-frameENST00000267085ENST00000545132CSADchr12

53553904

-ZYG11Bchr1

53222130

+
In-frameENST00000379846ENST00000294353CSADchr12

53553904

-ZYG11Bchr1

53222130

+
In-frameENST00000379846ENST00000443756CSADchr12

53553904

-ZYG11Bchr1

53222130

+
In-frameENST00000379846ENST00000545132CSADchr12

53553904

-ZYG11Bchr1

53222130

+
In-frameENST00000453446ENST00000294353CSADchr12

53553904

-ZYG11Bchr1

53222130

+
In-frameENST00000453446ENST00000443756CSADchr12

53553904

-ZYG11Bchr1

53222130

+
In-frameENST00000453446ENST00000545132CSADchr12

53553904

-ZYG11Bchr1

53222130

+
intron-3CDSENST00000491654ENST00000294353CSADchr12

53553904

-ZYG11Bchr1

53222130

+
intron-3CDSENST00000491654ENST00000443756CSADchr12

53553904

-ZYG11Bchr1

53222130

+
intron-3CDSENST00000491654ENST00000545132CSADchr12

53553904

-ZYG11Bchr1

53222130

+
intron-3CDSENST00000542115ENST00000294353CSADchr12

53553904

-ZYG11Bchr1

53222130

+
intron-3CDSENST00000542115ENST00000443756CSADchr12

53553904

-ZYG11Bchr1

53222130

+
intron-3CDSENST00000542115ENST00000545132CSADchr12

53553904

-ZYG11Bchr1

53222130

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000267085CSADchr1253553904-ENST00000443756ZYG11Bchr153222130+3576148112143475753
ENST00000267085CSADchr1253553904-ENST00000545132ZYG11Bchr153222130+3558148112143151645
ENST00000267085CSADchr1253553904-ENST00000294353ZYG11Bchr153222130+9399148112143685823
ENST00000379846CSADchr1253553904-ENST00000443756ZYG11Bchr153222130+29248295622823753
ENST00000379846CSADchr1253553904-ENST00000545132ZYG11Bchr153222130+29068295622499645
ENST00000379846CSADchr1253553904-ENST00000294353ZYG11Bchr153222130+87478295623033823
ENST00000453446CSADchr1253553904-ENST00000443756ZYG11Bchr153222130+3553145811913452753
ENST00000453446CSADchr1253553904-ENST00000545132ZYG11Bchr153222130+3535145811913128645
ENST00000453446CSADchr1253553904-ENST00000294353ZYG11Bchr153222130+9376145811913662823

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000267085ENST00000443756CSADchr1253553904-ZYG11Bchr153222130+0.0113099150.9886901
ENST00000267085ENST00000545132CSADchr1253553904-ZYG11Bchr153222130+0.0103807580.9896192
ENST00000267085ENST00000294353CSADchr1253553904-ZYG11Bchr153222130+0.0005721190.99942786
ENST00000379846ENST00000443756CSADchr1253553904-ZYG11Bchr153222130+0.0101910590.9898089
ENST00000379846ENST00000545132CSADchr1253553904-ZYG11Bchr153222130+0.0079064490.9920935
ENST00000379846ENST00000294353CSADchr1253553904-ZYG11Bchr153222130+0.0004810560.999519
ENST00000453446ENST00000443756CSADchr1253553904-ZYG11Bchr153222130+0.0112712320.98872876
ENST00000453446ENST00000545132CSADchr1253553904-ZYG11Bchr153222130+0.0093581970.9906418
ENST00000453446ENST00000294353CSADchr1253553904-ZYG11Bchr153222130+0.0005676760.99943227

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Fusion Genomic Features for CSAD-ZYG11B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CSADchr1253553903-ZYG11Bchr153222129+8.80E-091
CSADchr1253553903-ZYG11Bchr153222129+8.80E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CSAD-ZYG11B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:53553904/chr1:53222130)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneZYG11Bchr12:53553904chr1:53222130ENST00000294353014185_20810745.0RepeatNote=LRR 1
TgeneZYG11Bchr12:53553904chr1:53222130ENST00000294353014216_23610745.0RepeatNote=LRR 2
TgeneZYG11Bchr12:53553904chr1:53222130ENST00000294353014237_26110745.0RepeatNote=LRR 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for CSAD-ZYG11B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>19641_19641_1_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000267085_ZYG11B_chr1_53222130_ENST00000294353_length(transcript)=9399nt_BP=1481nt
GCTTGGGGACGCACGGAGAGGTGCAGCTGGGCCGTCCAGCATCAAACACTAGCCTCCACACGTGGAAAAGACCCTGACTCCCACAGTAGA
CTAGTCTTATGGGAGTCCTGGCTCTTGGGCCAGGCTGCATTAGGAAAATGGAAACCAGACTGTCTTCAAATTCTTCTGCCTAGCCTTAGC
CATTAGAGAGAGGTCCTGCTAAAGATGGACTGCAAATGCGCTTGATGGAAGGAGATGTCAATTCCACTGAAGTCCTCATTTCTGCTGAGC
TACCTGTGCACCCTGCCTCCGGCTCTCCTGAGCAGAGAGATCCTGATGGCTGACTCAGAAGCACTCCCCTCCCTTGCTGGGGACCCAGTG
GCTGTGGAAGCCTTGCTCCGGGCCGTGTTTGGGGTTGTTGTGGATGAGGCCATTCAGAAAGGAACCAGTGTCTCCCAGAAGGTCTGTGAG
TGGAAGGAGCCTGAGGAGCTGAAGCAGCTGCTGGATTTGGAGCTGCGGAGCCAGGGCGAGTCACAGAAGCAGATCCTGGAGCGGTGTCGG
GCTGTGATTCGCTACAGTGTCAAGACTGGTCACCCTCGGTTCTTCAACCAGCTCTTCTCTGGGTTGGATCCCCATGCTCTGGCCGGGCGC
ATTATCACTGAGAGCCTCAACACCAGCCAGTACACATATGAAATCGCCCCCGTGTTTGTGCTCATGGAAGAGGAGGTGCTGAGGAAACTG
CGGGCCCTGGTGGGCTGGAGCTCTGGGGACGGAATCTTCTGCCCTGGTGGCTCCATCTCCAACATGTATGCTGTAAATCTGGCCCGCTAT
CAGCGCTACCCGGATTGCAAGCAGAGGGGCCTCCGCACACTGCCGCCCCTGGCCCTATTCACATCGAAGGAGTGTCACTACTCCATCCAG
AAGGGAGCTGCGTTTCTGGGACTTGGCACCGACAGTGTCCGAGTGGTCAAGGCTGATGAGAGAGGGAAAATGGTCCCCGAGGATCTGGAG
AGGCAGATTGGTATGGCCGAGGCTGAGGGTGCTGTGCCGTTCCTGGTCAGTGCCACCTCTGGCACCACTGTGCTAGGGGCCTTTGACCCC
CTGGAGGCAATTGCTGATGTGTGCCAGCGTCATGGGCTATGGCTGCATGTGGATGCTGCCTGGGGTGGGAGCGTCCTGCTGTCACAGACA
CACAGGCATCTCCTGGATGGGATCCAGAGGGCTGACTCTGTGGCCTGGAATCCCCACAAGCTCCTCGCAGCAGGCCTGCAATGCTCTGCA
CTTCTTCTCCAGGATACCTCGAACCTGCTCAAGCGCTGCCATGGGTCCCAGGCCAGCTACCTTTTCCAGCAGGACAAGTTCTACGATGTG
GCTCTGGACACGGGAGACAAGGTGGTGCAGTGTGGCCGCCGTGTGGACTGTCTGAAGCTGTGGCTCATGTGGAAGGCACAGGGCGATCAA
GGGCTGGAGCGGCGCATCGACCAGGCCTTTGTCCTTGCCCGGAGGAGGCGTCTCCCTATTCCTTACTTGATATCTGCTTGAATTTCTTGA
CTACTCACCTTGAGAAGTTCTGTTCAGCCAGACAAGATGGAACATTGTGTCTGCAGGAACCTGGAGTATTCCCACAGGAGGTGGCTGATC
GACTGCTTCGGACCATGGCTTTTCATGGTCTATTGAATGATGGAACTGTGGGTATTTTTAGGGGCAACCAGATGCGCTTAAAGCGAGCCT
GCATTCGCAAAGCAAAGATCTCTGCTGTTGCTTTCCGGAAAGCTTTCTGCCACCACAAGTTAGTGGAACTTGATGCCACAGGTGTGAATG
CTGATATCACGATTACAGACATTATCAGTGGGCTTGGCAGTAACAAATGGATCCAGCAGAATCTCCAGTGCCTGGTGCTGAATTCATTAA
CTCTCTCCCTCGAGGATCCTTACGAGCGCTGCTTCAGCCGGCTTTCTGGCCTTCGAGCTTTAAGCATCACGAATGTTCTCTTTTACAATG
AAGACCTGGCTGAAGTTGCCTCATTGCCAAGATTAGAGAGCTTGGATATTTCTAACACCTCAATCACAGACATCACTGCTCTACTGGCCT
GCAAAGACCGACTCAAGTCTCTAACCATGCACCACTTGAAATGTTTAAAAATGACAACTACCCAGATACTGGATGTAGTTCGGGAACTCA
AACATCTGAATCATCTTGATATCTCAGATGATAAACAGTTTACATCAGACATAGCTCTTCGCTTACTAGAACAAAAAGACATCCTACCTA
ACCTTGTTTCTCTGGATGTTTCTGGGAGAAAGCACGTGACAGATAAAGCCGTTGAAGCCTTTATACAACAACGTCCAAGCATGCAATTTG
TAGGTTTGCTGGCTACTGATGCTGGTTACTCTGAATTCCTCACAGGCGAAGGACATTTGAAGGTGTCTGGGGAAGCCAATGAAACTCAGA
TTGCAGAAGCACTGAAGCGTTACAGTGAACGGGCATTCTTTGTTCGGGAAGCTCTATTTCATCTTTTTAGTCTGACTCATGTGATGGAAA
AAACAAAGCCAGAAATTTTAAAGCTTGTGGTTACTGGGATGAGAAACCACCCTATGAATTTGCCAGTGCAACTGGCTGCAAGCGCCTGTG
TATTTAACTTAACCAAGCAGGATCTTGCTGCAGGGATGCCTGTCCGACTCCTGGCTGATGTGACCCATTTGCTGCTCAAAGCCATGGAAC
ATTTTCCCAATCACCAGCAGTTACAGAAGAATTGCCTCCTTTCACTTTGCAGTGACCGGATCCTTCAAGATGTTCCATTTAACAGGTTTG
AAGCAGCCAAGCTTGTCATGCAGTGGCTTTGCAACCATGAGGATCAAAACATGCAAAGGATGGCAGTTGCTATCATTTCTATCCTGGCTG
CCAAGCTTTCTACAGAACAAACTGCACAGCTTGGTACTGAGCTCTTCATTGTCAGGCAACTTCTTCAAATAGTGAAGCAGAAAACCAATC
AAAATTCAGTGGACACTACATTGAAATTTACTTTGAGTGCACTTTGGAACCTCACAGATGAATCTCCAACCACTTGTAGACACTTTATTG
AAAACCAAGGGTTAGAACTCTTCATGAGGGTTCTAGAGTCTTTCCCAACTGAGTCATCCATTCAGCAGAAAGTTCTAGGACTTTTGAACA
ATATAGCTGAAGTACAAGAATTACATTCTGAATTAATGTGGAAAGATTTTATAGACCACATCAGTAGTCTCCTACACAGTGTGGAAGTGG
AAGTCAGTTACTTTGCAGCTGGAATTATTGCCCATTTAATATCCAGAGGTGAACAAGCTTGGACATTGAGTCGTAGCCAGAGGAATTCTC
TGCTGGATGATTTGCATTCAGCTATTTTGAAATGGCCAACTCCAGAGTGTGAGATGGTAGCATACAGGTCCTTTAATCCATTTTTCCCAT
TACTTGGCTGTTTCACAACACCAGGAGTTCAGCTATGGGCAGTTTGGGCCATGCAACATGTCTGCAGCAAGAATCCTTCAAGGTATTGCA
GCATGCTGATTGAAGAAGGAGGATTGCAGCATTTATACAACATCAAAGATCATGAACATACTGATCCCCATGTCCAACAGATTGCTGTGG
CCATTCTGGATAGCTTAGAAAAACACATTGTGCGCCATGGGAGGCCACCTCCCTGTAAAAAACAGCCCCAAGCCAGACTAAATTGATAGC
CATAAGTATTGGATAGTTGAATCACAGGAATCCTTTTTGTGATTGGTCCATTTGGAATATCTTACCCTCCCTGATGTTTTGGGGGTTTCT
ATGACAAGAGTCATAAAATCAGTTTGGGATTGATAATGTGTAGTACTGCCCATGTGAACAGTCTCTAATTTGTCTTGTGATTTTAAACTT
ATGAGTCAAGAAGGGTCTCTTCCTTTATCATTGCCTTTTAGGAAATTTTCCACATCTTTCAGTGTTTGAACTTACTTGTGCTTGAGATTC
TACAGTTTTATGGTAAAGTTTGCACGAACCCTTAGGCCAGACTTTTCTGATCTCAGAGTCCCTTCCAATCAATTTGCAGCTTCACATAAG
CTGTTGACCTGATTTCTGACACTGCTTCAGTTGTAAATTTTATACTGCTTCTGTATAAAATGCCTTTCTTCTCTATCTGTGTATATTTTA
TAAGATGTCCTTCTTAGTGTGAAAGAAGGGAAATGTGGATCATCTTGTGGAAGCTAATCACTGGCAGGAGCCTGGATGGCTGGCGGAAAG
ATATATGAGAAAGAAAAATTATGAAGGTAGAACAGAGTGTAGGAACTGGGAATTGGTTTCATGGTATAGGTTTTAAAATGAGACAGGCTA
CCCTTCGGGAGTCCACCTCTCTTGAGGCGGTGAGCAGAAGCTTGTCCTCCATATTTATACCTAGAAGTGTGGACTGCTGGTTCCTGCACA
GACTGCCGGTTATTCACTAGGAATATTTCCCCAAGCACCACAGTATAAAATACTACAGCACTCTGTGTTAAAGACTAACTGTCTACATCT
CCATATGTTGTAGTGTTGTGAAAATGTGATTTTAAAAAATTATCGCCAGTTAAAACTGGCTATTCTTTTCCTCTATTTCAAAGTCATTTT
TGTTCAGTGGAATAGAGACAGCAACATGGTGTTAACCTCTCAATTAAAATACAATTGACACCAGTAAATTTTGCCATAAAAAGTTAAAAT
CTCTTGTTCAAAATATGTGTATCTTCTTAATGTGTTCATGTTAGAGAAAGTGTCCCCATCTCACTGCCAAAAATGAAAGAAAATAATTAA
ACTCTTTAAATGATTAAATGTAATGATTCTACTCGCAGTGCATAACAGCACATATTTTTGACAGATTATTTTTTAGGCAATTACCTTTCC
TTAAGGTATCTGATACAGTATAGTAAAGAATCACTTATATCAGTAATAGCACTTGAGAGATAGCAAGTCACCAAGAAACTTAATTTTCAT
TTAAAATTTTATTTTGTGAATAAGGTCAATCTACAATCCCAGATAACTACATTTTTTTTCATAGATGGCCAGTGTTTTCAACAGAGATTT
AAAATGGAATATTAAAATTATAGTGATTATTCAGAAGCATTTTAATTTAGAAAGGAGCTGGTTTGTTAGTTCACTGATGACATTTTTTGA
CAAACATTTTATACCATTATCACAATAATCAGACTTGAATTTTTTTTGGAGTTCCTTCATGTGAATGAAAACTGAGTTAAAAGAAAGTAG
GCATTTAGGTCTGGATGCAGTGGCTCATGCTTGTAATCCCAGCACTTTGGGAAGCTGAAGCAGGAGGATTGCTTGAGCCCAGAAGTTCAA
GACTAGCCTGGGCAACATAGTGAGACTCGGTCTCTACCAAAAAAAAAAATTTTTTTTTTTTAAATTAGCTGGGTGTGGTGGCACCTGGGA
AACAGAGCGAGACGCTGACTCAAATAAATATCTAAATAGATATTTAGAATCACTGAAAACCATATTAAATGCTGGGTTAATGCTGACTTA
ATTGGCTTAAGGAATTTTTATAGGCGTAAGATAAATTTTCACAGACTAAGTTTATTTCAGACAAAATAGAGAATTCTTTTAAAAGTTTTT
TTTTTTTTTTTCCTTTTTCGAATGTTAATGTCTAAGACAAAGTTCAGAAAACGAGATGGCCTGTGGTAGTTTGGAAATTGCTAGATATGT
TGACCGTTTCCAGGTCTTTTATCTAGTGTAGTTAAGGGAAAGCCTATTTAAGAAGTTTGGCTTCAAGTTTCTGTTTTATAAGACAAAAGT
GCATATTTCTTTACAGGCTAATGCTAGGTTTTTGTCTTTACAAATTATTTTCAGAAATGGCTAAAAGTGTACAGAAAACAGTAAATCCCT
TCTTTACTCAGAATAACTTCTTAATAGTTGAAGCATCCAAAATATGTAAAAGCAAGGGTGGGCGTAGTGGCTCTTGCCTGTAATCCCAGC
ATTCTGGGAGGCCGAGGCGGGCAGATCACTTGAGATCAGGAGTTCGAGACCACCCTGGCCAACGTGGTGAAACCCCGTCTCTACTAAAAA
TACAAAAACTAGCTGGGCATGGTGGCTTTTTTGCACGCCTATAGTCCCAGCTACTCGGGAGGCTGAGGCACGAGAATCACTTGAACCCAG
GAAGTGGAGGTTGCAGTGAGCTAAGATCGTGCCACTGCACTCCAGCCTGGACAACGGAGTGAGACTCTGGGGAAAAAAAAAATTAAACTT
CCTACTTTTTTTCTTTTTGTAGAGACAGAGTTTCACTCTGTCGCCCAAGCTGGAGTGCAGTGGCACAATCATACCTCACTGCAGCCTCTT
GGGCTTATGTGATCTTACCCCCTCAGCCTCTGGAGTAGCTGGAACTACAGGCTAAATTTCCTACTTTGTAAACATCAGTAGTGGCCAGAT
ACTTCTGAGTCTTAAAAGCATAATAGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATCACA
AGGTCAGGAGTTCAAGACCAGCCTGGCCCAAATGGTGAAACCCTGTCTCTACTAAATATACAAAAATTAGCTGGGTGTGGTGGCGGGCAC
CTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGTGGAGGTTGTGGTGAGCCAATATCATGCCACTGC
ACTCCAGCCTGGGTGACAGAGTAAGACTCCGTCTCAAAAAAAAAAAAAGCATAATAATTTATTACATCCCAAATATATAAAAATTTGAGT
GCCTTTGCAGTTGGGATGGTTCCTAAAATTGCGTATAGAATTAAGGCACAGAATTGTGTGTAAGGTCCTGAATCTGGCTAAAATACAGTG
GATGTATGTATTGGAATTATGAGGCATAAGTAGCCAGTATCTATAGTTAGAATCTACAAGGCCTCCTTTTTGCACCTGTAGACTAGAATA
TAACTGTTATTGGTGCCTTTGAGTGTTATCTCTCAGTGGCTAGAGGTGCTGTTTCAAGCACAATTTAGACTAGGGTTGAACCACTCATTG
TTCAAATCATTGGTGGGCTCCAATGTAAAATATCACTACATCAGTCCACAAGCAACATTAAGGAAATCTAAAGGAAATGGAATTTGACTT
TTTAGAGTATAATGATGTTCTAGGGCATAATGAGGAAAATTTTTAAAAAATAGATTATAATGATACATATTGGTATCATTAAGACAACAG
ATTTGAGCAAATACAATTAAGGTGTCTTATTTTTTGCATCAAGTAATTATTGCTGTGGTCTTTCTACTCCACAAAATAATTTTTTCTTTT
TGCAGTTGAAAATTAACTGCATTATTAACTAATTAATAAAATAAATCAAGTGGTATAAGGGATTAGTTTACCCTCAAGCCGATGACTCCA
TGGCTACTGATATTAGTTAGTTTAGGATTTTTAAAAAGCATATCAGACCCCCAGTTTCAGGAATTGAGTATAAATATTGCTTCTTGTCAC
CCTGGGACAGTAATGCCTTATAGTGGCACTAGTCACCTTAAGTAGATTACACATGGTTGAGGTGAATAAAGCTGCATGGGAATTTGCTTT
CGTGATATATTTCATTTGCAAACTTCTACATAATCAAGTTTTATGTTTAAAACCATCGGTTCTATATATCTAGCTTTAGGAAGTTGCCCT
TACAGGTGGGACCTTTTGTGTTAATCTGTTTTCTCCCCAGTCATCTTATTTGGCTATGTTAAAAAAAAAAAAAAAAAAAAAGCGAGAGAG
AGAGATGGTGTCTCACTGTGTTGCCCAGGCTGGTCTCGAACTCCTGGCCTCAAGTGACTTTCCCACCTCAGCTTCCCAAAGTGCTGGAAT
CACAGGCATGAGCCACAGTGCCTGGTCTTAGCTGTGTTTTTAATTATGCCATGCATCAACATAACACCGGGCCATCTTCCTATCCCTTCC
TATCCCATATGTTTAATGAAAACATATTTTATGTGCTAAATTAGGTTAATTTACCAGAGATTTAGCTTAGTGTTTTTAAACTATAGAACA
ATACCCCTATAGAACAATGTACAGCTGCACCCAAGGTTAAAAAGAGGTAGCAGGGAAAACAAACTTAAACTCTTTGTATATGGTGAAACC
CATCCCTCTCCTGCCCTCTAATGGTATGTTTACATTATTTCGTTATTATACAATGTAGTGGTATAAACAGTATTATTAAACTGAAGGCAT
AAGTTAAAGGAAGTATGTTACTTTGAGCTGATGTAGGCTCTTCCACTTTTATCTGTATTTTACTTATTTGGGGACTTTGTATTGCTAGGG
CTTCAGAATACTAACTTTGACACAGCTCCCAGAGAGGTTTGCAAACTTTTGGTTTCCCTCTCAAATCCATGGTAGTAGTTTCAAATGAGT
TTGTGGATAATGGATGTTTAGTCCTTATCATTTGCTGTGTTTTGACAGTTTTTAATTTGCAGTATTCACTCACGAACTGTTTTATTTTAG
GAATAATGCAAAACCAACCTTCGTCCGGTGATGAGAATAGCCGTATGATAAGAGAATTTGCTCATCGTGCTTTAAATGATTAACTGTTTT
ACCTTATTTAGTATTTCATAGACTTTGCATGATATGGTACACTCCTAATTATGCATTCTTTGGTTTCCAAATCTTAATCTAAGATACTTT
GTTAACTGACTGGTAGCCTAAGAAAGAGACTTTTCTTCCTGTTTTTCTCTCTCCCCATTTTTTGGGGTAAGTTTTGCAAAGATCAGTGCT
GCTTCTCATGACTCTAAAGTAAAGCTCTTTTGGATAGCACAGCCTAACTTTACAGCTAGACAGAATGGCCATTAAGAATATTTCCAAAAT
CCAAGTTTATCAAAATTATTTTGTGGGAAATCATCAATCTATTTTATTAATGTTATGTGTTTAATTTTGGACTTATTTTGGGAAAAACTG
TTCAAATTGGGTCCTTTTAAGCTTATTTTAAGCAGCCTAGAAGGAAGAAGCTACTTAGCTAATGAAAGCTGAGACACTTTATTAAAAGCA
GGATCTTAAGAGCATTGTTTTTCCTTAAAAACTTTATACTCTCAGATAATCTGCAACAACAAAAATTAAGAAATCCCTGACTTTTGTAGA
ATTCCCACTGTCAAATTCTCACTGACTTATGAGTGTGAGAGAAGTTATCTTTTGTTTGAATTCTGATAGAACAGTTTAACTCCTTTCTAA
GGATATAAAAAATTCATTGGAAAGTGTGTATATTTCAAAGACTCTCAATTATCTGGACTGAAGGCACTGTTCTCACTATGGCCAGATGAA
TGGGAGTATTCTGTACATGAATCATGCTGTATTTTAAATCAGGACATCACTTAAGTATTAATGTTGTGTGTACAGATTTTTGTTTTGGGA

>19641_19641_1_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000267085_ZYG11B_chr1_53222130_ENST00000294353_length(amino acids)=823AA_BP=76
MESPQAPRSRPAMLCTSSPGYLEPAQALPWVPGQLPFPAGQVLRCGSGHGRQGGAVWPPCGLSEAVAHVEGTGRSRAGAAHRPGLCPCPE
EASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVFPQEVADRLLRTMAFHGLLNDGTVGIFRGNQMRLKRACIRKAKISAVAFRKA
FCHHKLVELDATGVNADITITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLESL
DISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTD
KAVEAFIQQRPSMQFVGLLATDAGYSEFLTGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLTHVMEKTKPEILKLVVTGMR
NHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCLLSLCSDRILQDVPFNRFEAAKLVMQWLCNHED
QNMQRMAVAIISILAAKLSTEQTAQLGTELFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVLESF
PTESSIQQKVLGLLNNIAEVQELHSELMWKDFIDHISSLLHSVEVEVSYFAAGIIAHLISRGEQAWTLSRSQRNSLLDDLHSAILKWPTP
ECEMVAYRSFNPFFPLLGCFTTPGVQLWAVWAMQHVCSKNPSRYCSMLIEEGGLQHLYNIKDHEHTDPHVQQIAVAILDSLEKHIVRHGR

--------------------------------------------------------------
>19641_19641_2_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000267085_ZYG11B_chr1_53222130_ENST00000443756_length(transcript)=3576nt_BP=1481nt
GCTTGGGGACGCACGGAGAGGTGCAGCTGGGCCGTCCAGCATCAAACACTAGCCTCCACACGTGGAAAAGACCCTGACTCCCACAGTAGA
CTAGTCTTATGGGAGTCCTGGCTCTTGGGCCAGGCTGCATTAGGAAAATGGAAACCAGACTGTCTTCAAATTCTTCTGCCTAGCCTTAGC
CATTAGAGAGAGGTCCTGCTAAAGATGGACTGCAAATGCGCTTGATGGAAGGAGATGTCAATTCCACTGAAGTCCTCATTTCTGCTGAGC
TACCTGTGCACCCTGCCTCCGGCTCTCCTGAGCAGAGAGATCCTGATGGCTGACTCAGAAGCACTCCCCTCCCTTGCTGGGGACCCAGTG
GCTGTGGAAGCCTTGCTCCGGGCCGTGTTTGGGGTTGTTGTGGATGAGGCCATTCAGAAAGGAACCAGTGTCTCCCAGAAGGTCTGTGAG
TGGAAGGAGCCTGAGGAGCTGAAGCAGCTGCTGGATTTGGAGCTGCGGAGCCAGGGCGAGTCACAGAAGCAGATCCTGGAGCGGTGTCGG
GCTGTGATTCGCTACAGTGTCAAGACTGGTCACCCTCGGTTCTTCAACCAGCTCTTCTCTGGGTTGGATCCCCATGCTCTGGCCGGGCGC
ATTATCACTGAGAGCCTCAACACCAGCCAGTACACATATGAAATCGCCCCCGTGTTTGTGCTCATGGAAGAGGAGGTGCTGAGGAAACTG
CGGGCCCTGGTGGGCTGGAGCTCTGGGGACGGAATCTTCTGCCCTGGTGGCTCCATCTCCAACATGTATGCTGTAAATCTGGCCCGCTAT
CAGCGCTACCCGGATTGCAAGCAGAGGGGCCTCCGCACACTGCCGCCCCTGGCCCTATTCACATCGAAGGAGTGTCACTACTCCATCCAG
AAGGGAGCTGCGTTTCTGGGACTTGGCACCGACAGTGTCCGAGTGGTCAAGGCTGATGAGAGAGGGAAAATGGTCCCCGAGGATCTGGAG
AGGCAGATTGGTATGGCCGAGGCTGAGGGTGCTGTGCCGTTCCTGGTCAGTGCCACCTCTGGCACCACTGTGCTAGGGGCCTTTGACCCC
CTGGAGGCAATTGCTGATGTGTGCCAGCGTCATGGGCTATGGCTGCATGTGGATGCTGCCTGGGGTGGGAGCGTCCTGCTGTCACAGACA
CACAGGCATCTCCTGGATGGGATCCAGAGGGCTGACTCTGTGGCCTGGAATCCCCACAAGCTCCTCGCAGCAGGCCTGCAATGCTCTGCA
CTTCTTCTCCAGGATACCTCGAACCTGCTCAAGCGCTGCCATGGGTCCCAGGCCAGCTACCTTTTCCAGCAGGACAAGTTCTACGATGTG
GCTCTGGACACGGGAGACAAGGTGGTGCAGTGTGGCCGCCGTGTGGACTGTCTGAAGCTGTGGCTCATGTGGAAGGCACAGGGCGATCAA
GGGCTGGAGCGGCGCATCGACCAGGCCTTTGTCCTTGCCCGGAGGAGGCGTCTCCCTATTCCTTACTTGATATCTGCTTGAATTTCTTGA
CTACTCACCTTGAGAAGTTCTGTTCAGCCAGACAAGATGGAACATTGTGTCTGCAGGAACCTGGAGTATTCCCACAGGAGGTGGCTGATC
GACTGCTTCGGACCATGGCTTTTCATGGTCTATTGAATGATGGAACTGTGGGTATTTTTAGGGGCAACCAGATGCGCTTAAAGCGAGCCT
GCATTCGCAAAGCAAAGATCTCTGCTGTTGCTTTCCGGAAAGCTTTCTGCCACCACAAGTTAGTGGAACTTGATGCCACAGGTGTGAATG
CTGATATCACGATTACAGACATTATCAGTGGGCTTGGCAGTAACAAATGGATCCAGCAGAATCTCCAGTGCCTGGTGCTGAATTCATTAA
CTCTCTCCCTCGAGGATCCTTACGAGCGCTGCTTCAGCCGGCTTTCTGGCCTTCGAGCTTTAAGCATCACGAATGTTCTCTTTTACAATG
AAGACCTGGCTGAAGTTGCCTCATTGCCAAGATTAGAGAGCTTGGATATTTCTAACACCTCAATCACAGACATCACTGCTCTACTGGCCT
GCAAAGACCGACTCAAGTCTCTAACCATGCACCACTTGAAATGTTTAAAAATGACAACTACCCAGATACTGGATGTAGTTCGGGAACTCA
AACATCTGAATCATCTTGATATCTCAGATGATAAACAGTTTACATCAGACATAGCTCTTCGCTTACTAGAACAAAAAGACATCCTACCTA
ACCTTGTTTCTCTGGATGTTTCTGGGAGAAAGCACGTGACAGATAAAGCCGTTGAAGCCTTTATACAACAACGTCCAAGCATGCAATTTG
TAGGTTTGCTGGCTACTGATGCTGGTTACTCTGAATTCCTCACAGGCGAAGGACATTTGAAGGTGTCTGGGGAAGCCAATGAAACTCAGA
TTGCAGAAGCACTGAAGCGTTACAGTGAACGGGCATTCTTTGTTCGGGAAGCTCTATTTCATCTTTTTAGTCTGACTCATGTGATGGAAA
AAACAAAGCCAGAAATTTTAAAGCTTGTGGTTACTGGGATGAGAAACCACCCTATGAATTTGCCAGTGCAACTGGCTGCAAGCGCCTGTG
TATTTAACTTAACCAAGCAGGATCTTGCTGCAGGGATGCCTGTCCGACTCCTGGCTGATGTGACCCATTTGCTGCTCAAAGCCATGGAAC
ATTTTCCCAATCACCAGCAGTTACAGAAGAATTGCCTCCTTTCACTTTGCAGTGACCGGATCCTTCAAGATGTTCCATTTAACAGGTTTG
AAGCAGCCAAGCTTGTCATGCAGTGGCTTTGCAACCATGAGGATCAAAACATGCAAAGGATGGCAGTTGCTATCATTTCTATCCTGGCTG
CCAAGCTTTCTACAGAACAAACTGCACAGCTTGGTACTGAGCTCTTCATTGTCAGGAACAATATAGCTGAAGTACAAGAATTACATTCTG
AATTAATGTGGAAAGATTTTATAGACCACATCAGTAGTCTCCTACACAGTGTGGAAGTGGAAGTCAGTTACTTTGCAGCTGGAATTATTG
CCCATTTAATATCCAGAGGTGAACAAGCTTGGACATTGAGTCGTAGCCAGAGGAATTCTCTGCTGGATGATTTGCATTCAGCTATTTTGA
AATGGCCAACTCCAGAGTGTGAGATGGTAGCATACAGGTCCTTTAATCCATTTTTCCCATTACTTGGCTGTTTCACAACACCAGGAGTTC
AGCTATGGGCAGTTTGGGCCATGCAACATGTCTGCAGCAAGAATCCTTCAAGGTATTGCAGCATGCTGATTGAAGAAGGAGGATTGCAGC
ATTTATACAACATCAAAGATCATGAACATACTGATCCCCATGTCCAACAGATTGCTGTGGCCATTCTGGATAGCTTAGAAAAACACATTG
TGCGCCATGGGAGGCCACCTCCCTGTAAAAAACAGCCCCAAGCCAGACTAAATTGATAGCCATAAGTATTGGATAGTTGAATCACAGGAA

>19641_19641_2_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000267085_ZYG11B_chr1_53222130_ENST00000443756_length(amino acids)=753AA_BP=76
MESPQAPRSRPAMLCTSSPGYLEPAQALPWVPGQLPFPAGQVLRCGSGHGRQGGAVWPPCGLSEAVAHVEGTGRSRAGAAHRPGLCPCPE
EASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVFPQEVADRLLRTMAFHGLLNDGTVGIFRGNQMRLKRACIRKAKISAVAFRKA
FCHHKLVELDATGVNADITITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLESL
DISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTD
KAVEAFIQQRPSMQFVGLLATDAGYSEFLTGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLTHVMEKTKPEILKLVVTGMR
NHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCLLSLCSDRILQDVPFNRFEAAKLVMQWLCNHED
QNMQRMAVAIISILAAKLSTEQTAQLGTELFIVRNNIAEVQELHSELMWKDFIDHISSLLHSVEVEVSYFAAGIIAHLISRGEQAWTLSR
SQRNSLLDDLHSAILKWPTPECEMVAYRSFNPFFPLLGCFTTPGVQLWAVWAMQHVCSKNPSRYCSMLIEEGGLQHLYNIKDHEHTDPHV

--------------------------------------------------------------
>19641_19641_3_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000267085_ZYG11B_chr1_53222130_ENST00000545132_length(transcript)=3558nt_BP=1481nt
GCTTGGGGACGCACGGAGAGGTGCAGCTGGGCCGTCCAGCATCAAACACTAGCCTCCACACGTGGAAAAGACCCTGACTCCCACAGTAGA
CTAGTCTTATGGGAGTCCTGGCTCTTGGGCCAGGCTGCATTAGGAAAATGGAAACCAGACTGTCTTCAAATTCTTCTGCCTAGCCTTAGC
CATTAGAGAGAGGTCCTGCTAAAGATGGACTGCAAATGCGCTTGATGGAAGGAGATGTCAATTCCACTGAAGTCCTCATTTCTGCTGAGC
TACCTGTGCACCCTGCCTCCGGCTCTCCTGAGCAGAGAGATCCTGATGGCTGACTCAGAAGCACTCCCCTCCCTTGCTGGGGACCCAGTG
GCTGTGGAAGCCTTGCTCCGGGCCGTGTTTGGGGTTGTTGTGGATGAGGCCATTCAGAAAGGAACCAGTGTCTCCCAGAAGGTCTGTGAG
TGGAAGGAGCCTGAGGAGCTGAAGCAGCTGCTGGATTTGGAGCTGCGGAGCCAGGGCGAGTCACAGAAGCAGATCCTGGAGCGGTGTCGG
GCTGTGATTCGCTACAGTGTCAAGACTGGTCACCCTCGGTTCTTCAACCAGCTCTTCTCTGGGTTGGATCCCCATGCTCTGGCCGGGCGC
ATTATCACTGAGAGCCTCAACACCAGCCAGTACACATATGAAATCGCCCCCGTGTTTGTGCTCATGGAAGAGGAGGTGCTGAGGAAACTG
CGGGCCCTGGTGGGCTGGAGCTCTGGGGACGGAATCTTCTGCCCTGGTGGCTCCATCTCCAACATGTATGCTGTAAATCTGGCCCGCTAT
CAGCGCTACCCGGATTGCAAGCAGAGGGGCCTCCGCACACTGCCGCCCCTGGCCCTATTCACATCGAAGGAGTGTCACTACTCCATCCAG
AAGGGAGCTGCGTTTCTGGGACTTGGCACCGACAGTGTCCGAGTGGTCAAGGCTGATGAGAGAGGGAAAATGGTCCCCGAGGATCTGGAG
AGGCAGATTGGTATGGCCGAGGCTGAGGGTGCTGTGCCGTTCCTGGTCAGTGCCACCTCTGGCACCACTGTGCTAGGGGCCTTTGACCCC
CTGGAGGCAATTGCTGATGTGTGCCAGCGTCATGGGCTATGGCTGCATGTGGATGCTGCCTGGGGTGGGAGCGTCCTGCTGTCACAGACA
CACAGGCATCTCCTGGATGGGATCCAGAGGGCTGACTCTGTGGCCTGGAATCCCCACAAGCTCCTCGCAGCAGGCCTGCAATGCTCTGCA
CTTCTTCTCCAGGATACCTCGAACCTGCTCAAGCGCTGCCATGGGTCCCAGGCCAGCTACCTTTTCCAGCAGGACAAGTTCTACGATGTG
GCTCTGGACACGGGAGACAAGGTGGTGCAGTGTGGCCGCCGTGTGGACTGTCTGAAGCTGTGGCTCATGTGGAAGGCACAGGGCGATCAA
GGGCTGGAGCGGCGCATCGACCAGGCCTTTGTCCTTGCCCGGAGGAGGCGTCTCCCTATTCCTTACTTGATATCTGCTTGAATTTCTTGA
CTACTCACCTTGAGAAGTTCTGTTCAGCCAGACAAGATGGAACATTGTGTCTGCAGGAACCTGGAGTATTCCCACAGGAGGTGGCTGATC
GACTGCTTCGGACCATGGCTTTTCATGGTCTATTGAATGATGGAACTGTGGGTATTTTTAGGGGCAACCAGATGCGCTTAAAGCGAGCCT
GCATTCGCAAAGCAAAGATCTCTGCTGTTGCTTTCCGGAAAGCTTTCTGCCACCACAAGTTAGTGGAACTTGATGCCACAGGTGTGAATG
CTGATATCACGATTACAGACATTATCAGTGGGCTTGGCAGTAACAAATGGATCCAGCAGAATCTCCAGTGCCTGGTGCTGAATTCATTAA
CTCTCTCCCTCGAGGATCCTTACGAGCGCTGCTTCAGCCGGCTTTCTGGCCTTCGAGCTTTAAGCATCACGAATGTTCTCTTTTACAATG
AAGACCTGGCTGAAGTTGCCTCATTGCCAAGATTAGAGAGCTTGGATATTTCTAACACCTCAATCACAGACATCACTGCTCTACTGGCCT
GCAAAGACCGACTCAAGTCTCTAACCATGCACCACTTGAAATGTTTAAAAATGACAACTACCCAGATACTGGATGTAGTTCGGGAACTCA
AACATCTGAATCATCTTGATATCTCAGATGATAAACAGTTTACATCAGACATAGCTCTTCGCTTACTAGAACAAAAAGACATCCTACCTA
ACCTTGTTTCTCTGGATGTTTCTGGGAGAAAGCACGTGACAGATAAAGCCGTTGAAGCCTTTATACAACAACGTCCAAGCATGCAATTTG
TAGGTTTGCTGGCTACTGATGCTGGTTACTCTGAATTCCTCACAGGCGAAGGACATTTGAAGGTGTCTGGGGAAGCCAATGAAACTCAGA
TTGCAGAAGCACTGAAGCGTTACAGTGAACGGGCATTCTTTGTTCGGGAAGCTCTATTTCATCTTTTTAGTCTGACTCATGTGATGGAAA
AAACAAAGCCAGAAATTTTAAAGCTTGTGGTTACTGGGATGAGAAACCACCCTATGAATTTGCCAGTGCAACTGGCTGCAAGCGCCTGTG
TATTTAACTTAACCAAGCAGGATCTTGCTGCAGGGATGCCTGTCCGACTCCTGGCTGATGTGACCCATTTGCTGCTCAAAGCCATGGAAC
ATTTTCCCAATCACCAGCAGTTACAGAAGAATTGCCTCCTTTCACTTTGCAGTGACCGGATCCTTCAAGATGTTCCATTTAACAGGTTTG
AAGCAGCCAAGCTTGTCATGCAGTGGCTTTGCAACCATGAGGATCAAAACATGCAAAGGATGGCAGTTGCTATCATTTCTATCCTGGCTG
CCAAGCTTTCTACAGAACAAACTGCACAGCTTGGTACTGAGCTCTTCATTGTCAGGCAACTTCTTCAAATAGTGAAGCAGAAAACCAATC
AAAATTCAGTGGACACTACATTGAAATTTACTTTGAGTGCACTTTGGAACCTCACAGATGAATCTCCAACCACTTGTAGACACTTTATTG
AAAACCAAGGGTTAGAACTCTTCATGAGGGTTCTAGAGTCTTTCCCAACTGAGTCATCCATTCAGCAGAAAGTTCTAGGACTTTTGGGTT
AATATGATTATTTGATACAGAAGTTGGCTCAGGTCATCTGAAACGGAAAGAACAATATAGCTGAAGTACAAGAATTACATTCTGAATTAA
TGTGGAAAGATTTTATAGACCACATCAGTAGTCTCCTACACAGTGTGGAAGTGGAAGTCAGTTACTTTGCAGCTGGAATTATTGCCCATT
TAATATCCAGAGGTGAACAAGCTTGGACATTGAGTCGTAGCCAGAGGAATTCTCTGCTGGATGATTTGCATTCAGCTATTTTGAAATGGC
CAACTCCAGAGTGTGAGATGGTAGCATACAGGTCCTTTAATCCATTTTTCCCATTACTTGGCTGTTTCACAACACCAGGAGTTCAGCTAT

>19641_19641_3_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000267085_ZYG11B_chr1_53222130_ENST00000545132_length(amino acids)=645AA_BP=76
MESPQAPRSRPAMLCTSSPGYLEPAQALPWVPGQLPFPAGQVLRCGSGHGRQGGAVWPPCGLSEAVAHVEGTGRSRAGAAHRPGLCPCPE
EASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVFPQEVADRLLRTMAFHGLLNDGTVGIFRGNQMRLKRACIRKAKISAVAFRKA
FCHHKLVELDATGVNADITITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLESL
DISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTD
KAVEAFIQQRPSMQFVGLLATDAGYSEFLTGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLTHVMEKTKPEILKLVVTGMR
NHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCLLSLCSDRILQDVPFNRFEAAKLVMQWLCNHED
QNMQRMAVAIISILAAKLSTEQTAQLGTELFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVLESF

--------------------------------------------------------------
>19641_19641_4_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000379846_ZYG11B_chr1_53222130_ENST00000294353_length(transcript)=8747nt_BP=829nt
GCTTGGGGACGCACGGAGAGGTGCAGCTGGGGTGGCTCACACCTGTAATCCCAGCACGTTGGGAAGCCGAGGTGGGGAATGACTCTGCTC
TGCCACAGATCCTGATGGCTGACTCAGAAGCACTCCCCTCCCTTGCTGGGGACCCAGTGGCTGTGGAAGCCTTGCTCCGGGCCGTGTTTG
GGGTTGTTGTGGATGAGGCCATTCAGAAAGGAACCAGTGTCTCCCAGAAGTGTCACTACTCCATCCAGAAGGGAGCTGCGTTTCTGGGAC
TTGGCACCGACAGTGTCCGAGTGGTCAAGGCTGATGAGAGAGGGAAAATGGTCCCCGAGGATCTGGAGAGGCAGATTGGTATGGCCGAGG
CTGAGGGTGCTGTGCCGTTCCTGGTCAGTGCCACCTCTGGCACCACTGTGCTAGGGGCCTTTGACCCCCTGGAGGCAATTGCTGATGTGT
GCCAGCGTCATGGGCTATGGCTGCATGTGGATGCTGCCTGGGGTGGGAGCGTCCTGCTGTCACAGACACACAGGCATCTCCTGGATGGGA
TCCAGAGGGCTGACTCTGTGGCCTGGAATCCCCACAAGCTCCTCGCAGCAGGCCTGCAATGCTCTGCACTTCTTCTCCAGGATACCTCGA
ACCTGCTCAAGCGCTGCCATGGGTCCCAGGCCAGCTACCTTTTCCAGCAGGACAAGTTCTACGATGTGGCTCTGGACACGGGAGACAAGG
TGGTGCAGTGTGGCCGCCGTGTGGACTGTCTGAAGCTGTGGCTCATGTGGAAGGCACAGGGCGATCAAGGGCTGGAGCGGCGCATCGACC
AGGCCTTTGTCCTTGCCCGGAGGAGGCGTCTCCCTATTCCTTACTTGATATCTGCTTGAATTTCTTGACTACTCACCTTGAGAAGTTCTG
TTCAGCCAGACAAGATGGAACATTGTGTCTGCAGGAACCTGGAGTATTCCCACAGGAGGTGGCTGATCGACTGCTTCGGACCATGGCTTT
TCATGGTCTATTGAATGATGGAACTGTGGGTATTTTTAGGGGCAACCAGATGCGCTTAAAGCGAGCCTGCATTCGCAAAGCAAAGATCTC
TGCTGTTGCTTTCCGGAAAGCTTTCTGCCACCACAAGTTAGTGGAACTTGATGCCACAGGTGTGAATGCTGATATCACGATTACAGACAT
TATCAGTGGGCTTGGCAGTAACAAATGGATCCAGCAGAATCTCCAGTGCCTGGTGCTGAATTCATTAACTCTCTCCCTCGAGGATCCTTA
CGAGCGCTGCTTCAGCCGGCTTTCTGGCCTTCGAGCTTTAAGCATCACGAATGTTCTCTTTTACAATGAAGACCTGGCTGAAGTTGCCTC
ATTGCCAAGATTAGAGAGCTTGGATATTTCTAACACCTCAATCACAGACATCACTGCTCTACTGGCCTGCAAAGACCGACTCAAGTCTCT
AACCATGCACCACTTGAAATGTTTAAAAATGACAACTACCCAGATACTGGATGTAGTTCGGGAACTCAAACATCTGAATCATCTTGATAT
CTCAGATGATAAACAGTTTACATCAGACATAGCTCTTCGCTTACTAGAACAAAAAGACATCCTACCTAACCTTGTTTCTCTGGATGTTTC
TGGGAGAAAGCACGTGACAGATAAAGCCGTTGAAGCCTTTATACAACAACGTCCAAGCATGCAATTTGTAGGTTTGCTGGCTACTGATGC
TGGTTACTCTGAATTCCTCACAGGCGAAGGACATTTGAAGGTGTCTGGGGAAGCCAATGAAACTCAGATTGCAGAAGCACTGAAGCGTTA
CAGTGAACGGGCATTCTTTGTTCGGGAAGCTCTATTTCATCTTTTTAGTCTGACTCATGTGATGGAAAAAACAAAGCCAGAAATTTTAAA
GCTTGTGGTTACTGGGATGAGAAACCACCCTATGAATTTGCCAGTGCAACTGGCTGCAAGCGCCTGTGTATTTAACTTAACCAAGCAGGA
TCTTGCTGCAGGGATGCCTGTCCGACTCCTGGCTGATGTGACCCATTTGCTGCTCAAAGCCATGGAACATTTTCCCAATCACCAGCAGTT
ACAGAAGAATTGCCTCCTTTCACTTTGCAGTGACCGGATCCTTCAAGATGTTCCATTTAACAGGTTTGAAGCAGCCAAGCTTGTCATGCA
GTGGCTTTGCAACCATGAGGATCAAAACATGCAAAGGATGGCAGTTGCTATCATTTCTATCCTGGCTGCCAAGCTTTCTACAGAACAAAC
TGCACAGCTTGGTACTGAGCTCTTCATTGTCAGGCAACTTCTTCAAATAGTGAAGCAGAAAACCAATCAAAATTCAGTGGACACTACATT
GAAATTTACTTTGAGTGCACTTTGGAACCTCACAGATGAATCTCCAACCACTTGTAGACACTTTATTGAAAACCAAGGGTTAGAACTCTT
CATGAGGGTTCTAGAGTCTTTCCCAACTGAGTCATCCATTCAGCAGAAAGTTCTAGGACTTTTGAACAATATAGCTGAAGTACAAGAATT
ACATTCTGAATTAATGTGGAAAGATTTTATAGACCACATCAGTAGTCTCCTACACAGTGTGGAAGTGGAAGTCAGTTACTTTGCAGCTGG
AATTATTGCCCATTTAATATCCAGAGGTGAACAAGCTTGGACATTGAGTCGTAGCCAGAGGAATTCTCTGCTGGATGATTTGCATTCAGC
TATTTTGAAATGGCCAACTCCAGAGTGTGAGATGGTAGCATACAGGTCCTTTAATCCATTTTTCCCATTACTTGGCTGTTTCACAACACC
AGGAGTTCAGCTATGGGCAGTTTGGGCCATGCAACATGTCTGCAGCAAGAATCCTTCAAGGTATTGCAGCATGCTGATTGAAGAAGGAGG
ATTGCAGCATTTATACAACATCAAAGATCATGAACATACTGATCCCCATGTCCAACAGATTGCTGTGGCCATTCTGGATAGCTTAGAAAA
ACACATTGTGCGCCATGGGAGGCCACCTCCCTGTAAAAAACAGCCCCAAGCCAGACTAAATTGATAGCCATAAGTATTGGATAGTTGAAT
CACAGGAATCCTTTTTGTGATTGGTCCATTTGGAATATCTTACCCTCCCTGATGTTTTGGGGGTTTCTATGACAAGAGTCATAAAATCAG
TTTGGGATTGATAATGTGTAGTACTGCCCATGTGAACAGTCTCTAATTTGTCTTGTGATTTTAAACTTATGAGTCAAGAAGGGTCTCTTC
CTTTATCATTGCCTTTTAGGAAATTTTCCACATCTTTCAGTGTTTGAACTTACTTGTGCTTGAGATTCTACAGTTTTATGGTAAAGTTTG
CACGAACCCTTAGGCCAGACTTTTCTGATCTCAGAGTCCCTTCCAATCAATTTGCAGCTTCACATAAGCTGTTGACCTGATTTCTGACAC
TGCTTCAGTTGTAAATTTTATACTGCTTCTGTATAAAATGCCTTTCTTCTCTATCTGTGTATATTTTATAAGATGTCCTTCTTAGTGTGA
AAGAAGGGAAATGTGGATCATCTTGTGGAAGCTAATCACTGGCAGGAGCCTGGATGGCTGGCGGAAAGATATATGAGAAAGAAAAATTAT
GAAGGTAGAACAGAGTGTAGGAACTGGGAATTGGTTTCATGGTATAGGTTTTAAAATGAGACAGGCTACCCTTCGGGAGTCCACCTCTCT
TGAGGCGGTGAGCAGAAGCTTGTCCTCCATATTTATACCTAGAAGTGTGGACTGCTGGTTCCTGCACAGACTGCCGGTTATTCACTAGGA
ATATTTCCCCAAGCACCACAGTATAAAATACTACAGCACTCTGTGTTAAAGACTAACTGTCTACATCTCCATATGTTGTAGTGTTGTGAA
AATGTGATTTTAAAAAATTATCGCCAGTTAAAACTGGCTATTCTTTTCCTCTATTTCAAAGTCATTTTTGTTCAGTGGAATAGAGACAGC
AACATGGTGTTAACCTCTCAATTAAAATACAATTGACACCAGTAAATTTTGCCATAAAAAGTTAAAATCTCTTGTTCAAAATATGTGTAT
CTTCTTAATGTGTTCATGTTAGAGAAAGTGTCCCCATCTCACTGCCAAAAATGAAAGAAAATAATTAAACTCTTTAAATGATTAAATGTA
ATGATTCTACTCGCAGTGCATAACAGCACATATTTTTGACAGATTATTTTTTAGGCAATTACCTTTCCTTAAGGTATCTGATACAGTATA
GTAAAGAATCACTTATATCAGTAATAGCACTTGAGAGATAGCAAGTCACCAAGAAACTTAATTTTCATTTAAAATTTTATTTTGTGAATA
AGGTCAATCTACAATCCCAGATAACTACATTTTTTTTCATAGATGGCCAGTGTTTTCAACAGAGATTTAAAATGGAATATTAAAATTATA
GTGATTATTCAGAAGCATTTTAATTTAGAAAGGAGCTGGTTTGTTAGTTCACTGATGACATTTTTTGACAAACATTTTATACCATTATCA
CAATAATCAGACTTGAATTTTTTTTGGAGTTCCTTCATGTGAATGAAAACTGAGTTAAAAGAAAGTAGGCATTTAGGTCTGGATGCAGTG
GCTCATGCTTGTAATCCCAGCACTTTGGGAAGCTGAAGCAGGAGGATTGCTTGAGCCCAGAAGTTCAAGACTAGCCTGGGCAACATAGTG
AGACTCGGTCTCTACCAAAAAAAAAAATTTTTTTTTTTTAAATTAGCTGGGTGTGGTGGCACCTGGGAAACAGAGCGAGACGCTGACTCA
AATAAATATCTAAATAGATATTTAGAATCACTGAAAACCATATTAAATGCTGGGTTAATGCTGACTTAATTGGCTTAAGGAATTTTTATA
GGCGTAAGATAAATTTTCACAGACTAAGTTTATTTCAGACAAAATAGAGAATTCTTTTAAAAGTTTTTTTTTTTTTTTTCCTTTTTCGAA
TGTTAATGTCTAAGACAAAGTTCAGAAAACGAGATGGCCTGTGGTAGTTTGGAAATTGCTAGATATGTTGACCGTTTCCAGGTCTTTTAT
CTAGTGTAGTTAAGGGAAAGCCTATTTAAGAAGTTTGGCTTCAAGTTTCTGTTTTATAAGACAAAAGTGCATATTTCTTTACAGGCTAAT
GCTAGGTTTTTGTCTTTACAAATTATTTTCAGAAATGGCTAAAAGTGTACAGAAAACAGTAAATCCCTTCTTTACTCAGAATAACTTCTT
AATAGTTGAAGCATCCAAAATATGTAAAAGCAAGGGTGGGCGTAGTGGCTCTTGCCTGTAATCCCAGCATTCTGGGAGGCCGAGGCGGGC
AGATCACTTGAGATCAGGAGTTCGAGACCACCCTGGCCAACGTGGTGAAACCCCGTCTCTACTAAAAATACAAAAACTAGCTGGGCATGG
TGGCTTTTTTGCACGCCTATAGTCCCAGCTACTCGGGAGGCTGAGGCACGAGAATCACTTGAACCCAGGAAGTGGAGGTTGCAGTGAGCT
AAGATCGTGCCACTGCACTCCAGCCTGGACAACGGAGTGAGACTCTGGGGAAAAAAAAAATTAAACTTCCTACTTTTTTTCTTTTTGTAG
AGACAGAGTTTCACTCTGTCGCCCAAGCTGGAGTGCAGTGGCACAATCATACCTCACTGCAGCCTCTTGGGCTTATGTGATCTTACCCCC
TCAGCCTCTGGAGTAGCTGGAACTACAGGCTAAATTTCCTACTTTGTAAACATCAGTAGTGGCCAGATACTTCTGAGTCTTAAAAGCATA
ATAGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATCACAAGGTCAGGAGTTCAAGACCAGC
CTGGCCCAAATGGTGAAACCCTGTCTCTACTAAATATACAAAAATTAGCTGGGTGTGGTGGCGGGCACCTGTAATCCCAGCTACTCAGGA
GGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGTGGAGGTTGTGGTGAGCCAATATCATGCCACTGCACTCCAGCCTGGGTGACAGAGT
AAGACTCCGTCTCAAAAAAAAAAAAAGCATAATAATTTATTACATCCCAAATATATAAAAATTTGAGTGCCTTTGCAGTTGGGATGGTTC
CTAAAATTGCGTATAGAATTAAGGCACAGAATTGTGTGTAAGGTCCTGAATCTGGCTAAAATACAGTGGATGTATGTATTGGAATTATGA
GGCATAAGTAGCCAGTATCTATAGTTAGAATCTACAAGGCCTCCTTTTTGCACCTGTAGACTAGAATATAACTGTTATTGGTGCCTTTGA
GTGTTATCTCTCAGTGGCTAGAGGTGCTGTTTCAAGCACAATTTAGACTAGGGTTGAACCACTCATTGTTCAAATCATTGGTGGGCTCCA
ATGTAAAATATCACTACATCAGTCCACAAGCAACATTAAGGAAATCTAAAGGAAATGGAATTTGACTTTTTAGAGTATAATGATGTTCTA
GGGCATAATGAGGAAAATTTTTAAAAAATAGATTATAATGATACATATTGGTATCATTAAGACAACAGATTTGAGCAAATACAATTAAGG
TGTCTTATTTTTTGCATCAAGTAATTATTGCTGTGGTCTTTCTACTCCACAAAATAATTTTTTCTTTTTGCAGTTGAAAATTAACTGCAT
TATTAACTAATTAATAAAATAAATCAAGTGGTATAAGGGATTAGTTTACCCTCAAGCCGATGACTCCATGGCTACTGATATTAGTTAGTT
TAGGATTTTTAAAAAGCATATCAGACCCCCAGTTTCAGGAATTGAGTATAAATATTGCTTCTTGTCACCCTGGGACAGTAATGCCTTATA
GTGGCACTAGTCACCTTAAGTAGATTACACATGGTTGAGGTGAATAAAGCTGCATGGGAATTTGCTTTCGTGATATATTTCATTTGCAAA
CTTCTACATAATCAAGTTTTATGTTTAAAACCATCGGTTCTATATATCTAGCTTTAGGAAGTTGCCCTTACAGGTGGGACCTTTTGTGTT
AATCTGTTTTCTCCCCAGTCATCTTATTTGGCTATGTTAAAAAAAAAAAAAAAAAAAAAGCGAGAGAGAGAGATGGTGTCTCACTGTGTT
GCCCAGGCTGGTCTCGAACTCCTGGCCTCAAGTGACTTTCCCACCTCAGCTTCCCAAAGTGCTGGAATCACAGGCATGAGCCACAGTGCC
TGGTCTTAGCTGTGTTTTTAATTATGCCATGCATCAACATAACACCGGGCCATCTTCCTATCCCTTCCTATCCCATATGTTTAATGAAAA
CATATTTTATGTGCTAAATTAGGTTAATTTACCAGAGATTTAGCTTAGTGTTTTTAAACTATAGAACAATACCCCTATAGAACAATGTAC
AGCTGCACCCAAGGTTAAAAAGAGGTAGCAGGGAAAACAAACTTAAACTCTTTGTATATGGTGAAACCCATCCCTCTCCTGCCCTCTAAT
GGTATGTTTACATTATTTCGTTATTATACAATGTAGTGGTATAAACAGTATTATTAAACTGAAGGCATAAGTTAAAGGAAGTATGTTACT
TTGAGCTGATGTAGGCTCTTCCACTTTTATCTGTATTTTACTTATTTGGGGACTTTGTATTGCTAGGGCTTCAGAATACTAACTTTGACA
CAGCTCCCAGAGAGGTTTGCAAACTTTTGGTTTCCCTCTCAAATCCATGGTAGTAGTTTCAAATGAGTTTGTGGATAATGGATGTTTAGT
CCTTATCATTTGCTGTGTTTTGACAGTTTTTAATTTGCAGTATTCACTCACGAACTGTTTTATTTTAGGAATAATGCAAAACCAACCTTC
GTCCGGTGATGAGAATAGCCGTATGATAAGAGAATTTGCTCATCGTGCTTTAAATGATTAACTGTTTTACCTTATTTAGTATTTCATAGA
CTTTGCATGATATGGTACACTCCTAATTATGCATTCTTTGGTTTCCAAATCTTAATCTAAGATACTTTGTTAACTGACTGGTAGCCTAAG
AAAGAGACTTTTCTTCCTGTTTTTCTCTCTCCCCATTTTTTGGGGTAAGTTTTGCAAAGATCAGTGCTGCTTCTCATGACTCTAAAGTAA
AGCTCTTTTGGATAGCACAGCCTAACTTTACAGCTAGACAGAATGGCCATTAAGAATATTTCCAAAATCCAAGTTTATCAAAATTATTTT
GTGGGAAATCATCAATCTATTTTATTAATGTTATGTGTTTAATTTTGGACTTATTTTGGGAAAAACTGTTCAAATTGGGTCCTTTTAAGC
TTATTTTAAGCAGCCTAGAAGGAAGAAGCTACTTAGCTAATGAAAGCTGAGACACTTTATTAAAAGCAGGATCTTAAGAGCATTGTTTTT
CCTTAAAAACTTTATACTCTCAGATAATCTGCAACAACAAAAATTAAGAAATCCCTGACTTTTGTAGAATTCCCACTGTCAAATTCTCAC
TGACTTATGAGTGTGAGAGAAGTTATCTTTTGTTTGAATTCTGATAGAACAGTTTAACTCCTTTCTAAGGATATAAAAAATTCATTGGAA
AGTGTGTATATTTCAAAGACTCTCAATTATCTGGACTGAAGGCACTGTTCTCACTATGGCCAGATGAATGGGAGTATTCTGTACATGAAT
CATGCTGTATTTTAAATCAGGACATCACTTAAGTATTAATGTTGTGTGTACAGATTTTTGTTTTGGGATTTTTTTTGCCTAAATAAATGT

>19641_19641_4_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000379846_ZYG11B_chr1_53222130_ENST00000294353_length(amino acids)=823AA_BP=76
MESPQAPRSRPAMLCTSSPGYLEPAQALPWVPGQLPFPAGQVLRCGSGHGRQGGAVWPPCGLSEAVAHVEGTGRSRAGAAHRPGLCPCPE
EASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVFPQEVADRLLRTMAFHGLLNDGTVGIFRGNQMRLKRACIRKAKISAVAFRKA
FCHHKLVELDATGVNADITITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLESL
DISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTD
KAVEAFIQQRPSMQFVGLLATDAGYSEFLTGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLTHVMEKTKPEILKLVVTGMR
NHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCLLSLCSDRILQDVPFNRFEAAKLVMQWLCNHED
QNMQRMAVAIISILAAKLSTEQTAQLGTELFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVLESF
PTESSIQQKVLGLLNNIAEVQELHSELMWKDFIDHISSLLHSVEVEVSYFAAGIIAHLISRGEQAWTLSRSQRNSLLDDLHSAILKWPTP
ECEMVAYRSFNPFFPLLGCFTTPGVQLWAVWAMQHVCSKNPSRYCSMLIEEGGLQHLYNIKDHEHTDPHVQQIAVAILDSLEKHIVRHGR

--------------------------------------------------------------
>19641_19641_5_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000379846_ZYG11B_chr1_53222130_ENST00000443756_length(transcript)=2924nt_BP=829nt
GCTTGGGGACGCACGGAGAGGTGCAGCTGGGGTGGCTCACACCTGTAATCCCAGCACGTTGGGAAGCCGAGGTGGGGAATGACTCTGCTC
TGCCACAGATCCTGATGGCTGACTCAGAAGCACTCCCCTCCCTTGCTGGGGACCCAGTGGCTGTGGAAGCCTTGCTCCGGGCCGTGTTTG
GGGTTGTTGTGGATGAGGCCATTCAGAAAGGAACCAGTGTCTCCCAGAAGTGTCACTACTCCATCCAGAAGGGAGCTGCGTTTCTGGGAC
TTGGCACCGACAGTGTCCGAGTGGTCAAGGCTGATGAGAGAGGGAAAATGGTCCCCGAGGATCTGGAGAGGCAGATTGGTATGGCCGAGG
CTGAGGGTGCTGTGCCGTTCCTGGTCAGTGCCACCTCTGGCACCACTGTGCTAGGGGCCTTTGACCCCCTGGAGGCAATTGCTGATGTGT
GCCAGCGTCATGGGCTATGGCTGCATGTGGATGCTGCCTGGGGTGGGAGCGTCCTGCTGTCACAGACACACAGGCATCTCCTGGATGGGA
TCCAGAGGGCTGACTCTGTGGCCTGGAATCCCCACAAGCTCCTCGCAGCAGGCCTGCAATGCTCTGCACTTCTTCTCCAGGATACCTCGA
ACCTGCTCAAGCGCTGCCATGGGTCCCAGGCCAGCTACCTTTTCCAGCAGGACAAGTTCTACGATGTGGCTCTGGACACGGGAGACAAGG
TGGTGCAGTGTGGCCGCCGTGTGGACTGTCTGAAGCTGTGGCTCATGTGGAAGGCACAGGGCGATCAAGGGCTGGAGCGGCGCATCGACC
AGGCCTTTGTCCTTGCCCGGAGGAGGCGTCTCCCTATTCCTTACTTGATATCTGCTTGAATTTCTTGACTACTCACCTTGAGAAGTTCTG
TTCAGCCAGACAAGATGGAACATTGTGTCTGCAGGAACCTGGAGTATTCCCACAGGAGGTGGCTGATCGACTGCTTCGGACCATGGCTTT
TCATGGTCTATTGAATGATGGAACTGTGGGTATTTTTAGGGGCAACCAGATGCGCTTAAAGCGAGCCTGCATTCGCAAAGCAAAGATCTC
TGCTGTTGCTTTCCGGAAAGCTTTCTGCCACCACAAGTTAGTGGAACTTGATGCCACAGGTGTGAATGCTGATATCACGATTACAGACAT
TATCAGTGGGCTTGGCAGTAACAAATGGATCCAGCAGAATCTCCAGTGCCTGGTGCTGAATTCATTAACTCTCTCCCTCGAGGATCCTTA
CGAGCGCTGCTTCAGCCGGCTTTCTGGCCTTCGAGCTTTAAGCATCACGAATGTTCTCTTTTACAATGAAGACCTGGCTGAAGTTGCCTC
ATTGCCAAGATTAGAGAGCTTGGATATTTCTAACACCTCAATCACAGACATCACTGCTCTACTGGCCTGCAAAGACCGACTCAAGTCTCT
AACCATGCACCACTTGAAATGTTTAAAAATGACAACTACCCAGATACTGGATGTAGTTCGGGAACTCAAACATCTGAATCATCTTGATAT
CTCAGATGATAAACAGTTTACATCAGACATAGCTCTTCGCTTACTAGAACAAAAAGACATCCTACCTAACCTTGTTTCTCTGGATGTTTC
TGGGAGAAAGCACGTGACAGATAAAGCCGTTGAAGCCTTTATACAACAACGTCCAAGCATGCAATTTGTAGGTTTGCTGGCTACTGATGC
TGGTTACTCTGAATTCCTCACAGGCGAAGGACATTTGAAGGTGTCTGGGGAAGCCAATGAAACTCAGATTGCAGAAGCACTGAAGCGTTA
CAGTGAACGGGCATTCTTTGTTCGGGAAGCTCTATTTCATCTTTTTAGTCTGACTCATGTGATGGAAAAAACAAAGCCAGAAATTTTAAA
GCTTGTGGTTACTGGGATGAGAAACCACCCTATGAATTTGCCAGTGCAACTGGCTGCAAGCGCCTGTGTATTTAACTTAACCAAGCAGGA
TCTTGCTGCAGGGATGCCTGTCCGACTCCTGGCTGATGTGACCCATTTGCTGCTCAAAGCCATGGAACATTTTCCCAATCACCAGCAGTT
ACAGAAGAATTGCCTCCTTTCACTTTGCAGTGACCGGATCCTTCAAGATGTTCCATTTAACAGGTTTGAAGCAGCCAAGCTTGTCATGCA
GTGGCTTTGCAACCATGAGGATCAAAACATGCAAAGGATGGCAGTTGCTATCATTTCTATCCTGGCTGCCAAGCTTTCTACAGAACAAAC
TGCACAGCTTGGTACTGAGCTCTTCATTGTCAGGAACAATATAGCTGAAGTACAAGAATTACATTCTGAATTAATGTGGAAAGATTTTAT
AGACCACATCAGTAGTCTCCTACACAGTGTGGAAGTGGAAGTCAGTTACTTTGCAGCTGGAATTATTGCCCATTTAATATCCAGAGGTGA
ACAAGCTTGGACATTGAGTCGTAGCCAGAGGAATTCTCTGCTGGATGATTTGCATTCAGCTATTTTGAAATGGCCAACTCCAGAGTGTGA
GATGGTAGCATACAGGTCCTTTAATCCATTTTTCCCATTACTTGGCTGTTTCACAACACCAGGAGTTCAGCTATGGGCAGTTTGGGCCAT
GCAACATGTCTGCAGCAAGAATCCTTCAAGGTATTGCAGCATGCTGATTGAAGAAGGAGGATTGCAGCATTTATACAACATCAAAGATCA
TGAACATACTGATCCCCATGTCCAACAGATTGCTGTGGCCATTCTGGATAGCTTAGAAAAACACATTGTGCGCCATGGGAGGCCACCTCC
CTGTAAAAAACAGCCCCAAGCCAGACTAAATTGATAGCCATAAGTATTGGATAGTTGAATCACAGGAATCCTTTTTGTGATTGGTCCATT

>19641_19641_5_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000379846_ZYG11B_chr1_53222130_ENST00000443756_length(amino acids)=753AA_BP=76
MESPQAPRSRPAMLCTSSPGYLEPAQALPWVPGQLPFPAGQVLRCGSGHGRQGGAVWPPCGLSEAVAHVEGTGRSRAGAAHRPGLCPCPE
EASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVFPQEVADRLLRTMAFHGLLNDGTVGIFRGNQMRLKRACIRKAKISAVAFRKA
FCHHKLVELDATGVNADITITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLESL
DISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTD
KAVEAFIQQRPSMQFVGLLATDAGYSEFLTGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLTHVMEKTKPEILKLVVTGMR
NHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCLLSLCSDRILQDVPFNRFEAAKLVMQWLCNHED
QNMQRMAVAIISILAAKLSTEQTAQLGTELFIVRNNIAEVQELHSELMWKDFIDHISSLLHSVEVEVSYFAAGIIAHLISRGEQAWTLSR
SQRNSLLDDLHSAILKWPTPECEMVAYRSFNPFFPLLGCFTTPGVQLWAVWAMQHVCSKNPSRYCSMLIEEGGLQHLYNIKDHEHTDPHV

--------------------------------------------------------------
>19641_19641_6_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000379846_ZYG11B_chr1_53222130_ENST00000545132_length(transcript)=2906nt_BP=829nt
GCTTGGGGACGCACGGAGAGGTGCAGCTGGGGTGGCTCACACCTGTAATCCCAGCACGTTGGGAAGCCGAGGTGGGGAATGACTCTGCTC
TGCCACAGATCCTGATGGCTGACTCAGAAGCACTCCCCTCCCTTGCTGGGGACCCAGTGGCTGTGGAAGCCTTGCTCCGGGCCGTGTTTG
GGGTTGTTGTGGATGAGGCCATTCAGAAAGGAACCAGTGTCTCCCAGAAGTGTCACTACTCCATCCAGAAGGGAGCTGCGTTTCTGGGAC
TTGGCACCGACAGTGTCCGAGTGGTCAAGGCTGATGAGAGAGGGAAAATGGTCCCCGAGGATCTGGAGAGGCAGATTGGTATGGCCGAGG
CTGAGGGTGCTGTGCCGTTCCTGGTCAGTGCCACCTCTGGCACCACTGTGCTAGGGGCCTTTGACCCCCTGGAGGCAATTGCTGATGTGT
GCCAGCGTCATGGGCTATGGCTGCATGTGGATGCTGCCTGGGGTGGGAGCGTCCTGCTGTCACAGACACACAGGCATCTCCTGGATGGGA
TCCAGAGGGCTGACTCTGTGGCCTGGAATCCCCACAAGCTCCTCGCAGCAGGCCTGCAATGCTCTGCACTTCTTCTCCAGGATACCTCGA
ACCTGCTCAAGCGCTGCCATGGGTCCCAGGCCAGCTACCTTTTCCAGCAGGACAAGTTCTACGATGTGGCTCTGGACACGGGAGACAAGG
TGGTGCAGTGTGGCCGCCGTGTGGACTGTCTGAAGCTGTGGCTCATGTGGAAGGCACAGGGCGATCAAGGGCTGGAGCGGCGCATCGACC
AGGCCTTTGTCCTTGCCCGGAGGAGGCGTCTCCCTATTCCTTACTTGATATCTGCTTGAATTTCTTGACTACTCACCTTGAGAAGTTCTG
TTCAGCCAGACAAGATGGAACATTGTGTCTGCAGGAACCTGGAGTATTCCCACAGGAGGTGGCTGATCGACTGCTTCGGACCATGGCTTT
TCATGGTCTATTGAATGATGGAACTGTGGGTATTTTTAGGGGCAACCAGATGCGCTTAAAGCGAGCCTGCATTCGCAAAGCAAAGATCTC
TGCTGTTGCTTTCCGGAAAGCTTTCTGCCACCACAAGTTAGTGGAACTTGATGCCACAGGTGTGAATGCTGATATCACGATTACAGACAT
TATCAGTGGGCTTGGCAGTAACAAATGGATCCAGCAGAATCTCCAGTGCCTGGTGCTGAATTCATTAACTCTCTCCCTCGAGGATCCTTA
CGAGCGCTGCTTCAGCCGGCTTTCTGGCCTTCGAGCTTTAAGCATCACGAATGTTCTCTTTTACAATGAAGACCTGGCTGAAGTTGCCTC
ATTGCCAAGATTAGAGAGCTTGGATATTTCTAACACCTCAATCACAGACATCACTGCTCTACTGGCCTGCAAAGACCGACTCAAGTCTCT
AACCATGCACCACTTGAAATGTTTAAAAATGACAACTACCCAGATACTGGATGTAGTTCGGGAACTCAAACATCTGAATCATCTTGATAT
CTCAGATGATAAACAGTTTACATCAGACATAGCTCTTCGCTTACTAGAACAAAAAGACATCCTACCTAACCTTGTTTCTCTGGATGTTTC
TGGGAGAAAGCACGTGACAGATAAAGCCGTTGAAGCCTTTATACAACAACGTCCAAGCATGCAATTTGTAGGTTTGCTGGCTACTGATGC
TGGTTACTCTGAATTCCTCACAGGCGAAGGACATTTGAAGGTGTCTGGGGAAGCCAATGAAACTCAGATTGCAGAAGCACTGAAGCGTTA
CAGTGAACGGGCATTCTTTGTTCGGGAAGCTCTATTTCATCTTTTTAGTCTGACTCATGTGATGGAAAAAACAAAGCCAGAAATTTTAAA
GCTTGTGGTTACTGGGATGAGAAACCACCCTATGAATTTGCCAGTGCAACTGGCTGCAAGCGCCTGTGTATTTAACTTAACCAAGCAGGA
TCTTGCTGCAGGGATGCCTGTCCGACTCCTGGCTGATGTGACCCATTTGCTGCTCAAAGCCATGGAACATTTTCCCAATCACCAGCAGTT
ACAGAAGAATTGCCTCCTTTCACTTTGCAGTGACCGGATCCTTCAAGATGTTCCATTTAACAGGTTTGAAGCAGCCAAGCTTGTCATGCA
GTGGCTTTGCAACCATGAGGATCAAAACATGCAAAGGATGGCAGTTGCTATCATTTCTATCCTGGCTGCCAAGCTTTCTACAGAACAAAC
TGCACAGCTTGGTACTGAGCTCTTCATTGTCAGGCAACTTCTTCAAATAGTGAAGCAGAAAACCAATCAAAATTCAGTGGACACTACATT
GAAATTTACTTTGAGTGCACTTTGGAACCTCACAGATGAATCTCCAACCACTTGTAGACACTTTATTGAAAACCAAGGGTTAGAACTCTT
CATGAGGGTTCTAGAGTCTTTCCCAACTGAGTCATCCATTCAGCAGAAAGTTCTAGGACTTTTGGGTTAATATGATTATTTGATACAGAA
GTTGGCTCAGGTCATCTGAAACGGAAAGAACAATATAGCTGAAGTACAAGAATTACATTCTGAATTAATGTGGAAAGATTTTATAGACCA
CATCAGTAGTCTCCTACACAGTGTGGAAGTGGAAGTCAGTTACTTTGCAGCTGGAATTATTGCCCATTTAATATCCAGAGGTGAACAAGC
TTGGACATTGAGTCGTAGCCAGAGGAATTCTCTGCTGGATGATTTGCATTCAGCTATTTTGAAATGGCCAACTCCAGAGTGTGAGATGGT
AGCATACAGGTCCTTTAATCCATTTTTCCCATTACTTGGCTGTTTCACAACACCAGGAGTTCAGCTATGGGCAGTTTGGGCCATGCAACA

>19641_19641_6_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000379846_ZYG11B_chr1_53222130_ENST00000545132_length(amino acids)=645AA_BP=76
MESPQAPRSRPAMLCTSSPGYLEPAQALPWVPGQLPFPAGQVLRCGSGHGRQGGAVWPPCGLSEAVAHVEGTGRSRAGAAHRPGLCPCPE
EASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVFPQEVADRLLRTMAFHGLLNDGTVGIFRGNQMRLKRACIRKAKISAVAFRKA
FCHHKLVELDATGVNADITITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLESL
DISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTD
KAVEAFIQQRPSMQFVGLLATDAGYSEFLTGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLTHVMEKTKPEILKLVVTGMR
NHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCLLSLCSDRILQDVPFNRFEAAKLVMQWLCNHED
QNMQRMAVAIISILAAKLSTEQTAQLGTELFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVLESF

--------------------------------------------------------------
>19641_19641_7_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000453446_ZYG11B_chr1_53222130_ENST00000294353_length(transcript)=9376nt_BP=1458nt
ACTTCCGGGCTCGGCAGCTAGACTAGCGGGGGCAGCCTCAGAGCGGGCCGTCCAGCATCAAACACTAGCCTCCACACGTGGAAAAGACCC
TGACTCCCACAGTAGACTAGTCTTATGGGAGTCCTGGCTCTTGGGCCAGGCTGCATTAGGAAAATGGAAACCAGACTGTCTTCAAATTCT
TCTGCCTAGCCTTAGCCATTAGAGAGAGGTCCTGCTAAAGATGGACTGCAAATGCGCTTGATGGAAGGAGATGTCAATTCCACTGAAGTC
CTCATTTCTGCTGTAGATCCTGATGGCTGACTCAGAAGCACTCCCCTCCCTTGCTGGGGACCCAGTGGCTGTGGAAGCCTTGCTCCGGGC
CGTGTTTGGGGTTGTTGTGGATGAGGCCATTCAGAAAGGAACCAGTGTCTCCCAGAAGGTCTGTGAGTGGAAGGAGCCTGAGGAGCTGAA
GCAGCTGCTGGATTTGGAGCTGCGGAGCCAGGGCGAGTCACAGAAGCAGATCCTGGAGCGGTGTCGGGCTGTGATTCGCTACAGTGTCAA
GACTGGTCACCCTCGGTTCTTCAACCAGCTCTTCTCTGGGTTGGATCCCCATGCTCTGGCCGGGCGCATTATCACTGAGAGCCTCAACAC
CAGCCAGTACACATATGAAATCGCCCCCGTGTTTGTGCTCATGGAAGAGGAGGTGCTGAGGAAACTGCGGGCCCTGGTGGGCTGGAGCTC
TGGGGACGGAATCTTCTGCCCTGGTGGCTCCATCTCCAACATGTATGCTGTAAATCTGGCCCGCTATCAGCGCTACCCGGATTGCAAGCA
GAGGGGCCTCCGCACACTGCCGCCCCTGGCCCTATTCACATCGAAGGAGTGTCACTACTCCATCCAGAAGGGAGCTGCGTTTCTGGGACT
TGGCACCGACAGTGTCCGAGTGGTCAAGGCTGATGAGAGAGGGAAAATGGTCCCCGAGGATCTGGAGAGGCAGATTGGTATGGCCGAGGC
TGAGGGTGCTGTGCCGTTCCTGGTCAGTGCCACCTCTGGCACCACTGTGCTAGGGGCCTTTGACCCCCTGGAGGCAATTGCTGATGTGTG
CCAGCGTCATGGGCTATGGCTGCATGTGGATGCTGCCTGGGGTGGGAGCGTCCTGCTGTCACAGACACACAGGCATCTCCTGGATGGGAT
CCAGAGGGCTGACTCTGTGGCCTGGAATCCCCACAAGCTCCTCGCAGCAGGCCTGCAATGCTCTGCACTTCTTCTCCAGGATACCTCGAA
CCTGCTCAAGCGCTGCCATGGGTCCCAGGCCAGCTACCTTTTCCAGCAGGACAAGTTCTACGATGTGGCTCTGGACACGGGAGACAAGGT
GGTGCAGTGTGGCCGCCGTGTGGACTGTCTGAAGCTGTGGCTCATGTGGAAGGCACAGGGCGATCAAGGGCTGGAGCGGCGCATCGACCA
GGCCTTTGTCCTTGCCCGGAGGAGGCGTCTCCCTATTCCTTACTTGATATCTGCTTGAATTTCTTGACTACTCACCTTGAGAAGTTCTGT
TCAGCCAGACAAGATGGAACATTGTGTCTGCAGGAACCTGGAGTATTCCCACAGGAGGTGGCTGATCGACTGCTTCGGACCATGGCTTTT
CATGGTCTATTGAATGATGGAACTGTGGGTATTTTTAGGGGCAACCAGATGCGCTTAAAGCGAGCCTGCATTCGCAAAGCAAAGATCTCT
GCTGTTGCTTTCCGGAAAGCTTTCTGCCACCACAAGTTAGTGGAACTTGATGCCACAGGTGTGAATGCTGATATCACGATTACAGACATT
ATCAGTGGGCTTGGCAGTAACAAATGGATCCAGCAGAATCTCCAGTGCCTGGTGCTGAATTCATTAACTCTCTCCCTCGAGGATCCTTAC
GAGCGCTGCTTCAGCCGGCTTTCTGGCCTTCGAGCTTTAAGCATCACGAATGTTCTCTTTTACAATGAAGACCTGGCTGAAGTTGCCTCA
TTGCCAAGATTAGAGAGCTTGGATATTTCTAACACCTCAATCACAGACATCACTGCTCTACTGGCCTGCAAAGACCGACTCAAGTCTCTA
ACCATGCACCACTTGAAATGTTTAAAAATGACAACTACCCAGATACTGGATGTAGTTCGGGAACTCAAACATCTGAATCATCTTGATATC
TCAGATGATAAACAGTTTACATCAGACATAGCTCTTCGCTTACTAGAACAAAAAGACATCCTACCTAACCTTGTTTCTCTGGATGTTTCT
GGGAGAAAGCACGTGACAGATAAAGCCGTTGAAGCCTTTATACAACAACGTCCAAGCATGCAATTTGTAGGTTTGCTGGCTACTGATGCT
GGTTACTCTGAATTCCTCACAGGCGAAGGACATTTGAAGGTGTCTGGGGAAGCCAATGAAACTCAGATTGCAGAAGCACTGAAGCGTTAC
AGTGAACGGGCATTCTTTGTTCGGGAAGCTCTATTTCATCTTTTTAGTCTGACTCATGTGATGGAAAAAACAAAGCCAGAAATTTTAAAG
CTTGTGGTTACTGGGATGAGAAACCACCCTATGAATTTGCCAGTGCAACTGGCTGCAAGCGCCTGTGTATTTAACTTAACCAAGCAGGAT
CTTGCTGCAGGGATGCCTGTCCGACTCCTGGCTGATGTGACCCATTTGCTGCTCAAAGCCATGGAACATTTTCCCAATCACCAGCAGTTA
CAGAAGAATTGCCTCCTTTCACTTTGCAGTGACCGGATCCTTCAAGATGTTCCATTTAACAGGTTTGAAGCAGCCAAGCTTGTCATGCAG
TGGCTTTGCAACCATGAGGATCAAAACATGCAAAGGATGGCAGTTGCTATCATTTCTATCCTGGCTGCCAAGCTTTCTACAGAACAAACT
GCACAGCTTGGTACTGAGCTCTTCATTGTCAGGCAACTTCTTCAAATAGTGAAGCAGAAAACCAATCAAAATTCAGTGGACACTACATTG
AAATTTACTTTGAGTGCACTTTGGAACCTCACAGATGAATCTCCAACCACTTGTAGACACTTTATTGAAAACCAAGGGTTAGAACTCTTC
ATGAGGGTTCTAGAGTCTTTCCCAACTGAGTCATCCATTCAGCAGAAAGTTCTAGGACTTTTGAACAATATAGCTGAAGTACAAGAATTA
CATTCTGAATTAATGTGGAAAGATTTTATAGACCACATCAGTAGTCTCCTACACAGTGTGGAAGTGGAAGTCAGTTACTTTGCAGCTGGA
ATTATTGCCCATTTAATATCCAGAGGTGAACAAGCTTGGACATTGAGTCGTAGCCAGAGGAATTCTCTGCTGGATGATTTGCATTCAGCT
ATTTTGAAATGGCCAACTCCAGAGTGTGAGATGGTAGCATACAGGTCCTTTAATCCATTTTTCCCATTACTTGGCTGTTTCACAACACCA
GGAGTTCAGCTATGGGCAGTTTGGGCCATGCAACATGTCTGCAGCAAGAATCCTTCAAGGTATTGCAGCATGCTGATTGAAGAAGGAGGA
TTGCAGCATTTATACAACATCAAAGATCATGAACATACTGATCCCCATGTCCAACAGATTGCTGTGGCCATTCTGGATAGCTTAGAAAAA
CACATTGTGCGCCATGGGAGGCCACCTCCCTGTAAAAAACAGCCCCAAGCCAGACTAAATTGATAGCCATAAGTATTGGATAGTTGAATC
ACAGGAATCCTTTTTGTGATTGGTCCATTTGGAATATCTTACCCTCCCTGATGTTTTGGGGGTTTCTATGACAAGAGTCATAAAATCAGT
TTGGGATTGATAATGTGTAGTACTGCCCATGTGAACAGTCTCTAATTTGTCTTGTGATTTTAAACTTATGAGTCAAGAAGGGTCTCTTCC
TTTATCATTGCCTTTTAGGAAATTTTCCACATCTTTCAGTGTTTGAACTTACTTGTGCTTGAGATTCTACAGTTTTATGGTAAAGTTTGC
ACGAACCCTTAGGCCAGACTTTTCTGATCTCAGAGTCCCTTCCAATCAATTTGCAGCTTCACATAAGCTGTTGACCTGATTTCTGACACT
GCTTCAGTTGTAAATTTTATACTGCTTCTGTATAAAATGCCTTTCTTCTCTATCTGTGTATATTTTATAAGATGTCCTTCTTAGTGTGAA
AGAAGGGAAATGTGGATCATCTTGTGGAAGCTAATCACTGGCAGGAGCCTGGATGGCTGGCGGAAAGATATATGAGAAAGAAAAATTATG
AAGGTAGAACAGAGTGTAGGAACTGGGAATTGGTTTCATGGTATAGGTTTTAAAATGAGACAGGCTACCCTTCGGGAGTCCACCTCTCTT
GAGGCGGTGAGCAGAAGCTTGTCCTCCATATTTATACCTAGAAGTGTGGACTGCTGGTTCCTGCACAGACTGCCGGTTATTCACTAGGAA
TATTTCCCCAAGCACCACAGTATAAAATACTACAGCACTCTGTGTTAAAGACTAACTGTCTACATCTCCATATGTTGTAGTGTTGTGAAA
ATGTGATTTTAAAAAATTATCGCCAGTTAAAACTGGCTATTCTTTTCCTCTATTTCAAAGTCATTTTTGTTCAGTGGAATAGAGACAGCA
ACATGGTGTTAACCTCTCAATTAAAATACAATTGACACCAGTAAATTTTGCCATAAAAAGTTAAAATCTCTTGTTCAAAATATGTGTATC
TTCTTAATGTGTTCATGTTAGAGAAAGTGTCCCCATCTCACTGCCAAAAATGAAAGAAAATAATTAAACTCTTTAAATGATTAAATGTAA
TGATTCTACTCGCAGTGCATAACAGCACATATTTTTGACAGATTATTTTTTAGGCAATTACCTTTCCTTAAGGTATCTGATACAGTATAG
TAAAGAATCACTTATATCAGTAATAGCACTTGAGAGATAGCAAGTCACCAAGAAACTTAATTTTCATTTAAAATTTTATTTTGTGAATAA
GGTCAATCTACAATCCCAGATAACTACATTTTTTTTCATAGATGGCCAGTGTTTTCAACAGAGATTTAAAATGGAATATTAAAATTATAG
TGATTATTCAGAAGCATTTTAATTTAGAAAGGAGCTGGTTTGTTAGTTCACTGATGACATTTTTTGACAAACATTTTATACCATTATCAC
AATAATCAGACTTGAATTTTTTTTGGAGTTCCTTCATGTGAATGAAAACTGAGTTAAAAGAAAGTAGGCATTTAGGTCTGGATGCAGTGG
CTCATGCTTGTAATCCCAGCACTTTGGGAAGCTGAAGCAGGAGGATTGCTTGAGCCCAGAAGTTCAAGACTAGCCTGGGCAACATAGTGA
GACTCGGTCTCTACCAAAAAAAAAAATTTTTTTTTTTTAAATTAGCTGGGTGTGGTGGCACCTGGGAAACAGAGCGAGACGCTGACTCAA
ATAAATATCTAAATAGATATTTAGAATCACTGAAAACCATATTAAATGCTGGGTTAATGCTGACTTAATTGGCTTAAGGAATTTTTATAG
GCGTAAGATAAATTTTCACAGACTAAGTTTATTTCAGACAAAATAGAGAATTCTTTTAAAAGTTTTTTTTTTTTTTTTCCTTTTTCGAAT
GTTAATGTCTAAGACAAAGTTCAGAAAACGAGATGGCCTGTGGTAGTTTGGAAATTGCTAGATATGTTGACCGTTTCCAGGTCTTTTATC
TAGTGTAGTTAAGGGAAAGCCTATTTAAGAAGTTTGGCTTCAAGTTTCTGTTTTATAAGACAAAAGTGCATATTTCTTTACAGGCTAATG
CTAGGTTTTTGTCTTTACAAATTATTTTCAGAAATGGCTAAAAGTGTACAGAAAACAGTAAATCCCTTCTTTACTCAGAATAACTTCTTA
ATAGTTGAAGCATCCAAAATATGTAAAAGCAAGGGTGGGCGTAGTGGCTCTTGCCTGTAATCCCAGCATTCTGGGAGGCCGAGGCGGGCA
GATCACTTGAGATCAGGAGTTCGAGACCACCCTGGCCAACGTGGTGAAACCCCGTCTCTACTAAAAATACAAAAACTAGCTGGGCATGGT
GGCTTTTTTGCACGCCTATAGTCCCAGCTACTCGGGAGGCTGAGGCACGAGAATCACTTGAACCCAGGAAGTGGAGGTTGCAGTGAGCTA
AGATCGTGCCACTGCACTCCAGCCTGGACAACGGAGTGAGACTCTGGGGAAAAAAAAAATTAAACTTCCTACTTTTTTTCTTTTTGTAGA
GACAGAGTTTCACTCTGTCGCCCAAGCTGGAGTGCAGTGGCACAATCATACCTCACTGCAGCCTCTTGGGCTTATGTGATCTTACCCCCT
CAGCCTCTGGAGTAGCTGGAACTACAGGCTAAATTTCCTACTTTGTAAACATCAGTAGTGGCCAGATACTTCTGAGTCTTAAAAGCATAA
TAGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATCACAAGGTCAGGAGTTCAAGACCAGCC
TGGCCCAAATGGTGAAACCCTGTCTCTACTAAATATACAAAAATTAGCTGGGTGTGGTGGCGGGCACCTGTAATCCCAGCTACTCAGGAG
GCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGTGGAGGTTGTGGTGAGCCAATATCATGCCACTGCACTCCAGCCTGGGTGACAGAGTA
AGACTCCGTCTCAAAAAAAAAAAAAGCATAATAATTTATTACATCCCAAATATATAAAAATTTGAGTGCCTTTGCAGTTGGGATGGTTCC
TAAAATTGCGTATAGAATTAAGGCACAGAATTGTGTGTAAGGTCCTGAATCTGGCTAAAATACAGTGGATGTATGTATTGGAATTATGAG
GCATAAGTAGCCAGTATCTATAGTTAGAATCTACAAGGCCTCCTTTTTGCACCTGTAGACTAGAATATAACTGTTATTGGTGCCTTTGAG
TGTTATCTCTCAGTGGCTAGAGGTGCTGTTTCAAGCACAATTTAGACTAGGGTTGAACCACTCATTGTTCAAATCATTGGTGGGCTCCAA
TGTAAAATATCACTACATCAGTCCACAAGCAACATTAAGGAAATCTAAAGGAAATGGAATTTGACTTTTTAGAGTATAATGATGTTCTAG
GGCATAATGAGGAAAATTTTTAAAAAATAGATTATAATGATACATATTGGTATCATTAAGACAACAGATTTGAGCAAATACAATTAAGGT
GTCTTATTTTTTGCATCAAGTAATTATTGCTGTGGTCTTTCTACTCCACAAAATAATTTTTTCTTTTTGCAGTTGAAAATTAACTGCATT
ATTAACTAATTAATAAAATAAATCAAGTGGTATAAGGGATTAGTTTACCCTCAAGCCGATGACTCCATGGCTACTGATATTAGTTAGTTT
AGGATTTTTAAAAAGCATATCAGACCCCCAGTTTCAGGAATTGAGTATAAATATTGCTTCTTGTCACCCTGGGACAGTAATGCCTTATAG
TGGCACTAGTCACCTTAAGTAGATTACACATGGTTGAGGTGAATAAAGCTGCATGGGAATTTGCTTTCGTGATATATTTCATTTGCAAAC
TTCTACATAATCAAGTTTTATGTTTAAAACCATCGGTTCTATATATCTAGCTTTAGGAAGTTGCCCTTACAGGTGGGACCTTTTGTGTTA
ATCTGTTTTCTCCCCAGTCATCTTATTTGGCTATGTTAAAAAAAAAAAAAAAAAAAAAGCGAGAGAGAGAGATGGTGTCTCACTGTGTTG
CCCAGGCTGGTCTCGAACTCCTGGCCTCAAGTGACTTTCCCACCTCAGCTTCCCAAAGTGCTGGAATCACAGGCATGAGCCACAGTGCCT
GGTCTTAGCTGTGTTTTTAATTATGCCATGCATCAACATAACACCGGGCCATCTTCCTATCCCTTCCTATCCCATATGTTTAATGAAAAC
ATATTTTATGTGCTAAATTAGGTTAATTTACCAGAGATTTAGCTTAGTGTTTTTAAACTATAGAACAATACCCCTATAGAACAATGTACA
GCTGCACCCAAGGTTAAAAAGAGGTAGCAGGGAAAACAAACTTAAACTCTTTGTATATGGTGAAACCCATCCCTCTCCTGCCCTCTAATG
GTATGTTTACATTATTTCGTTATTATACAATGTAGTGGTATAAACAGTATTATTAAACTGAAGGCATAAGTTAAAGGAAGTATGTTACTT
TGAGCTGATGTAGGCTCTTCCACTTTTATCTGTATTTTACTTATTTGGGGACTTTGTATTGCTAGGGCTTCAGAATACTAACTTTGACAC
AGCTCCCAGAGAGGTTTGCAAACTTTTGGTTTCCCTCTCAAATCCATGGTAGTAGTTTCAAATGAGTTTGTGGATAATGGATGTTTAGTC
CTTATCATTTGCTGTGTTTTGACAGTTTTTAATTTGCAGTATTCACTCACGAACTGTTTTATTTTAGGAATAATGCAAAACCAACCTTCG
TCCGGTGATGAGAATAGCCGTATGATAAGAGAATTTGCTCATCGTGCTTTAAATGATTAACTGTTTTACCTTATTTAGTATTTCATAGAC
TTTGCATGATATGGTACACTCCTAATTATGCATTCTTTGGTTTCCAAATCTTAATCTAAGATACTTTGTTAACTGACTGGTAGCCTAAGA
AAGAGACTTTTCTTCCTGTTTTTCTCTCTCCCCATTTTTTGGGGTAAGTTTTGCAAAGATCAGTGCTGCTTCTCATGACTCTAAAGTAAA
GCTCTTTTGGATAGCACAGCCTAACTTTACAGCTAGACAGAATGGCCATTAAGAATATTTCCAAAATCCAAGTTTATCAAAATTATTTTG
TGGGAAATCATCAATCTATTTTATTAATGTTATGTGTTTAATTTTGGACTTATTTTGGGAAAAACTGTTCAAATTGGGTCCTTTTAAGCT
TATTTTAAGCAGCCTAGAAGGAAGAAGCTACTTAGCTAATGAAAGCTGAGACACTTTATTAAAAGCAGGATCTTAAGAGCATTGTTTTTC
CTTAAAAACTTTATACTCTCAGATAATCTGCAACAACAAAAATTAAGAAATCCCTGACTTTTGTAGAATTCCCACTGTCAAATTCTCACT
GACTTATGAGTGTGAGAGAAGTTATCTTTTGTTTGAATTCTGATAGAACAGTTTAACTCCTTTCTAAGGATATAAAAAATTCATTGGAAA
GTGTGTATATTTCAAAGACTCTCAATTATCTGGACTGAAGGCACTGTTCTCACTATGGCCAGATGAATGGGAGTATTCTGTACATGAATC
ATGCTGTATTTTAAATCAGGACATCACTTAAGTATTAATGTTGTGTGTACAGATTTTTGTTTTGGGATTTTTTTTGCCTAAATAAATGTT

>19641_19641_7_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000453446_ZYG11B_chr1_53222130_ENST00000294353_length(amino acids)=823AA_BP=76
MESPQAPRSRPAMLCTSSPGYLEPAQALPWVPGQLPFPAGQVLRCGSGHGRQGGAVWPPCGLSEAVAHVEGTGRSRAGAAHRPGLCPCPE
EASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVFPQEVADRLLRTMAFHGLLNDGTVGIFRGNQMRLKRACIRKAKISAVAFRKA
FCHHKLVELDATGVNADITITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLESL
DISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTD
KAVEAFIQQRPSMQFVGLLATDAGYSEFLTGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLTHVMEKTKPEILKLVVTGMR
NHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCLLSLCSDRILQDVPFNRFEAAKLVMQWLCNHED
QNMQRMAVAIISILAAKLSTEQTAQLGTELFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVLESF
PTESSIQQKVLGLLNNIAEVQELHSELMWKDFIDHISSLLHSVEVEVSYFAAGIIAHLISRGEQAWTLSRSQRNSLLDDLHSAILKWPTP
ECEMVAYRSFNPFFPLLGCFTTPGVQLWAVWAMQHVCSKNPSRYCSMLIEEGGLQHLYNIKDHEHTDPHVQQIAVAILDSLEKHIVRHGR

--------------------------------------------------------------
>19641_19641_8_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000453446_ZYG11B_chr1_53222130_ENST00000443756_length(transcript)=3553nt_BP=1458nt
ACTTCCGGGCTCGGCAGCTAGACTAGCGGGGGCAGCCTCAGAGCGGGCCGTCCAGCATCAAACACTAGCCTCCACACGTGGAAAAGACCC
TGACTCCCACAGTAGACTAGTCTTATGGGAGTCCTGGCTCTTGGGCCAGGCTGCATTAGGAAAATGGAAACCAGACTGTCTTCAAATTCT
TCTGCCTAGCCTTAGCCATTAGAGAGAGGTCCTGCTAAAGATGGACTGCAAATGCGCTTGATGGAAGGAGATGTCAATTCCACTGAAGTC
CTCATTTCTGCTGTAGATCCTGATGGCTGACTCAGAAGCACTCCCCTCCCTTGCTGGGGACCCAGTGGCTGTGGAAGCCTTGCTCCGGGC
CGTGTTTGGGGTTGTTGTGGATGAGGCCATTCAGAAAGGAACCAGTGTCTCCCAGAAGGTCTGTGAGTGGAAGGAGCCTGAGGAGCTGAA
GCAGCTGCTGGATTTGGAGCTGCGGAGCCAGGGCGAGTCACAGAAGCAGATCCTGGAGCGGTGTCGGGCTGTGATTCGCTACAGTGTCAA
GACTGGTCACCCTCGGTTCTTCAACCAGCTCTTCTCTGGGTTGGATCCCCATGCTCTGGCCGGGCGCATTATCACTGAGAGCCTCAACAC
CAGCCAGTACACATATGAAATCGCCCCCGTGTTTGTGCTCATGGAAGAGGAGGTGCTGAGGAAACTGCGGGCCCTGGTGGGCTGGAGCTC
TGGGGACGGAATCTTCTGCCCTGGTGGCTCCATCTCCAACATGTATGCTGTAAATCTGGCCCGCTATCAGCGCTACCCGGATTGCAAGCA
GAGGGGCCTCCGCACACTGCCGCCCCTGGCCCTATTCACATCGAAGGAGTGTCACTACTCCATCCAGAAGGGAGCTGCGTTTCTGGGACT
TGGCACCGACAGTGTCCGAGTGGTCAAGGCTGATGAGAGAGGGAAAATGGTCCCCGAGGATCTGGAGAGGCAGATTGGTATGGCCGAGGC
TGAGGGTGCTGTGCCGTTCCTGGTCAGTGCCACCTCTGGCACCACTGTGCTAGGGGCCTTTGACCCCCTGGAGGCAATTGCTGATGTGTG
CCAGCGTCATGGGCTATGGCTGCATGTGGATGCTGCCTGGGGTGGGAGCGTCCTGCTGTCACAGACACACAGGCATCTCCTGGATGGGAT
CCAGAGGGCTGACTCTGTGGCCTGGAATCCCCACAAGCTCCTCGCAGCAGGCCTGCAATGCTCTGCACTTCTTCTCCAGGATACCTCGAA
CCTGCTCAAGCGCTGCCATGGGTCCCAGGCCAGCTACCTTTTCCAGCAGGACAAGTTCTACGATGTGGCTCTGGACACGGGAGACAAGGT
GGTGCAGTGTGGCCGCCGTGTGGACTGTCTGAAGCTGTGGCTCATGTGGAAGGCACAGGGCGATCAAGGGCTGGAGCGGCGCATCGACCA
GGCCTTTGTCCTTGCCCGGAGGAGGCGTCTCCCTATTCCTTACTTGATATCTGCTTGAATTTCTTGACTACTCACCTTGAGAAGTTCTGT
TCAGCCAGACAAGATGGAACATTGTGTCTGCAGGAACCTGGAGTATTCCCACAGGAGGTGGCTGATCGACTGCTTCGGACCATGGCTTTT
CATGGTCTATTGAATGATGGAACTGTGGGTATTTTTAGGGGCAACCAGATGCGCTTAAAGCGAGCCTGCATTCGCAAAGCAAAGATCTCT
GCTGTTGCTTTCCGGAAAGCTTTCTGCCACCACAAGTTAGTGGAACTTGATGCCACAGGTGTGAATGCTGATATCACGATTACAGACATT
ATCAGTGGGCTTGGCAGTAACAAATGGATCCAGCAGAATCTCCAGTGCCTGGTGCTGAATTCATTAACTCTCTCCCTCGAGGATCCTTAC
GAGCGCTGCTTCAGCCGGCTTTCTGGCCTTCGAGCTTTAAGCATCACGAATGTTCTCTTTTACAATGAAGACCTGGCTGAAGTTGCCTCA
TTGCCAAGATTAGAGAGCTTGGATATTTCTAACACCTCAATCACAGACATCACTGCTCTACTGGCCTGCAAAGACCGACTCAAGTCTCTA
ACCATGCACCACTTGAAATGTTTAAAAATGACAACTACCCAGATACTGGATGTAGTTCGGGAACTCAAACATCTGAATCATCTTGATATC
TCAGATGATAAACAGTTTACATCAGACATAGCTCTTCGCTTACTAGAACAAAAAGACATCCTACCTAACCTTGTTTCTCTGGATGTTTCT
GGGAGAAAGCACGTGACAGATAAAGCCGTTGAAGCCTTTATACAACAACGTCCAAGCATGCAATTTGTAGGTTTGCTGGCTACTGATGCT
GGTTACTCTGAATTCCTCACAGGCGAAGGACATTTGAAGGTGTCTGGGGAAGCCAATGAAACTCAGATTGCAGAAGCACTGAAGCGTTAC
AGTGAACGGGCATTCTTTGTTCGGGAAGCTCTATTTCATCTTTTTAGTCTGACTCATGTGATGGAAAAAACAAAGCCAGAAATTTTAAAG
CTTGTGGTTACTGGGATGAGAAACCACCCTATGAATTTGCCAGTGCAACTGGCTGCAAGCGCCTGTGTATTTAACTTAACCAAGCAGGAT
CTTGCTGCAGGGATGCCTGTCCGACTCCTGGCTGATGTGACCCATTTGCTGCTCAAAGCCATGGAACATTTTCCCAATCACCAGCAGTTA
CAGAAGAATTGCCTCCTTTCACTTTGCAGTGACCGGATCCTTCAAGATGTTCCATTTAACAGGTTTGAAGCAGCCAAGCTTGTCATGCAG
TGGCTTTGCAACCATGAGGATCAAAACATGCAAAGGATGGCAGTTGCTATCATTTCTATCCTGGCTGCCAAGCTTTCTACAGAACAAACT
GCACAGCTTGGTACTGAGCTCTTCATTGTCAGGAACAATATAGCTGAAGTACAAGAATTACATTCTGAATTAATGTGGAAAGATTTTATA
GACCACATCAGTAGTCTCCTACACAGTGTGGAAGTGGAAGTCAGTTACTTTGCAGCTGGAATTATTGCCCATTTAATATCCAGAGGTGAA
CAAGCTTGGACATTGAGTCGTAGCCAGAGGAATTCTCTGCTGGATGATTTGCATTCAGCTATTTTGAAATGGCCAACTCCAGAGTGTGAG
ATGGTAGCATACAGGTCCTTTAATCCATTTTTCCCATTACTTGGCTGTTTCACAACACCAGGAGTTCAGCTATGGGCAGTTTGGGCCATG
CAACATGTCTGCAGCAAGAATCCTTCAAGGTATTGCAGCATGCTGATTGAAGAAGGAGGATTGCAGCATTTATACAACATCAAAGATCAT
GAACATACTGATCCCCATGTCCAACAGATTGCTGTGGCCATTCTGGATAGCTTAGAAAAACACATTGTGCGCCATGGGAGGCCACCTCCC
TGTAAAAAACAGCCCCAAGCCAGACTAAATTGATAGCCATAAGTATTGGATAGTTGAATCACAGGAATCCTTTTTGTGATTGGTCCATTT

>19641_19641_8_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000453446_ZYG11B_chr1_53222130_ENST00000443756_length(amino acids)=753AA_BP=76
MESPQAPRSRPAMLCTSSPGYLEPAQALPWVPGQLPFPAGQVLRCGSGHGRQGGAVWPPCGLSEAVAHVEGTGRSRAGAAHRPGLCPCPE
EASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVFPQEVADRLLRTMAFHGLLNDGTVGIFRGNQMRLKRACIRKAKISAVAFRKA
FCHHKLVELDATGVNADITITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLESL
DISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTD
KAVEAFIQQRPSMQFVGLLATDAGYSEFLTGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLTHVMEKTKPEILKLVVTGMR
NHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCLLSLCSDRILQDVPFNRFEAAKLVMQWLCNHED
QNMQRMAVAIISILAAKLSTEQTAQLGTELFIVRNNIAEVQELHSELMWKDFIDHISSLLHSVEVEVSYFAAGIIAHLISRGEQAWTLSR
SQRNSLLDDLHSAILKWPTPECEMVAYRSFNPFFPLLGCFTTPGVQLWAVWAMQHVCSKNPSRYCSMLIEEGGLQHLYNIKDHEHTDPHV

--------------------------------------------------------------
>19641_19641_9_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000453446_ZYG11B_chr1_53222130_ENST00000545132_length(transcript)=3535nt_BP=1458nt
ACTTCCGGGCTCGGCAGCTAGACTAGCGGGGGCAGCCTCAGAGCGGGCCGTCCAGCATCAAACACTAGCCTCCACACGTGGAAAAGACCC
TGACTCCCACAGTAGACTAGTCTTATGGGAGTCCTGGCTCTTGGGCCAGGCTGCATTAGGAAAATGGAAACCAGACTGTCTTCAAATTCT
TCTGCCTAGCCTTAGCCATTAGAGAGAGGTCCTGCTAAAGATGGACTGCAAATGCGCTTGATGGAAGGAGATGTCAATTCCACTGAAGTC
CTCATTTCTGCTGTAGATCCTGATGGCTGACTCAGAAGCACTCCCCTCCCTTGCTGGGGACCCAGTGGCTGTGGAAGCCTTGCTCCGGGC
CGTGTTTGGGGTTGTTGTGGATGAGGCCATTCAGAAAGGAACCAGTGTCTCCCAGAAGGTCTGTGAGTGGAAGGAGCCTGAGGAGCTGAA
GCAGCTGCTGGATTTGGAGCTGCGGAGCCAGGGCGAGTCACAGAAGCAGATCCTGGAGCGGTGTCGGGCTGTGATTCGCTACAGTGTCAA
GACTGGTCACCCTCGGTTCTTCAACCAGCTCTTCTCTGGGTTGGATCCCCATGCTCTGGCCGGGCGCATTATCACTGAGAGCCTCAACAC
CAGCCAGTACACATATGAAATCGCCCCCGTGTTTGTGCTCATGGAAGAGGAGGTGCTGAGGAAACTGCGGGCCCTGGTGGGCTGGAGCTC
TGGGGACGGAATCTTCTGCCCTGGTGGCTCCATCTCCAACATGTATGCTGTAAATCTGGCCCGCTATCAGCGCTACCCGGATTGCAAGCA
GAGGGGCCTCCGCACACTGCCGCCCCTGGCCCTATTCACATCGAAGGAGTGTCACTACTCCATCCAGAAGGGAGCTGCGTTTCTGGGACT
TGGCACCGACAGTGTCCGAGTGGTCAAGGCTGATGAGAGAGGGAAAATGGTCCCCGAGGATCTGGAGAGGCAGATTGGTATGGCCGAGGC
TGAGGGTGCTGTGCCGTTCCTGGTCAGTGCCACCTCTGGCACCACTGTGCTAGGGGCCTTTGACCCCCTGGAGGCAATTGCTGATGTGTG
CCAGCGTCATGGGCTATGGCTGCATGTGGATGCTGCCTGGGGTGGGAGCGTCCTGCTGTCACAGACACACAGGCATCTCCTGGATGGGAT
CCAGAGGGCTGACTCTGTGGCCTGGAATCCCCACAAGCTCCTCGCAGCAGGCCTGCAATGCTCTGCACTTCTTCTCCAGGATACCTCGAA
CCTGCTCAAGCGCTGCCATGGGTCCCAGGCCAGCTACCTTTTCCAGCAGGACAAGTTCTACGATGTGGCTCTGGACACGGGAGACAAGGT
GGTGCAGTGTGGCCGCCGTGTGGACTGTCTGAAGCTGTGGCTCATGTGGAAGGCACAGGGCGATCAAGGGCTGGAGCGGCGCATCGACCA
GGCCTTTGTCCTTGCCCGGAGGAGGCGTCTCCCTATTCCTTACTTGATATCTGCTTGAATTTCTTGACTACTCACCTTGAGAAGTTCTGT
TCAGCCAGACAAGATGGAACATTGTGTCTGCAGGAACCTGGAGTATTCCCACAGGAGGTGGCTGATCGACTGCTTCGGACCATGGCTTTT
CATGGTCTATTGAATGATGGAACTGTGGGTATTTTTAGGGGCAACCAGATGCGCTTAAAGCGAGCCTGCATTCGCAAAGCAAAGATCTCT
GCTGTTGCTTTCCGGAAAGCTTTCTGCCACCACAAGTTAGTGGAACTTGATGCCACAGGTGTGAATGCTGATATCACGATTACAGACATT
ATCAGTGGGCTTGGCAGTAACAAATGGATCCAGCAGAATCTCCAGTGCCTGGTGCTGAATTCATTAACTCTCTCCCTCGAGGATCCTTAC
GAGCGCTGCTTCAGCCGGCTTTCTGGCCTTCGAGCTTTAAGCATCACGAATGTTCTCTTTTACAATGAAGACCTGGCTGAAGTTGCCTCA
TTGCCAAGATTAGAGAGCTTGGATATTTCTAACACCTCAATCACAGACATCACTGCTCTACTGGCCTGCAAAGACCGACTCAAGTCTCTA
ACCATGCACCACTTGAAATGTTTAAAAATGACAACTACCCAGATACTGGATGTAGTTCGGGAACTCAAACATCTGAATCATCTTGATATC
TCAGATGATAAACAGTTTACATCAGACATAGCTCTTCGCTTACTAGAACAAAAAGACATCCTACCTAACCTTGTTTCTCTGGATGTTTCT
GGGAGAAAGCACGTGACAGATAAAGCCGTTGAAGCCTTTATACAACAACGTCCAAGCATGCAATTTGTAGGTTTGCTGGCTACTGATGCT
GGTTACTCTGAATTCCTCACAGGCGAAGGACATTTGAAGGTGTCTGGGGAAGCCAATGAAACTCAGATTGCAGAAGCACTGAAGCGTTAC
AGTGAACGGGCATTCTTTGTTCGGGAAGCTCTATTTCATCTTTTTAGTCTGACTCATGTGATGGAAAAAACAAAGCCAGAAATTTTAAAG
CTTGTGGTTACTGGGATGAGAAACCACCCTATGAATTTGCCAGTGCAACTGGCTGCAAGCGCCTGTGTATTTAACTTAACCAAGCAGGAT
CTTGCTGCAGGGATGCCTGTCCGACTCCTGGCTGATGTGACCCATTTGCTGCTCAAAGCCATGGAACATTTTCCCAATCACCAGCAGTTA
CAGAAGAATTGCCTCCTTTCACTTTGCAGTGACCGGATCCTTCAAGATGTTCCATTTAACAGGTTTGAAGCAGCCAAGCTTGTCATGCAG
TGGCTTTGCAACCATGAGGATCAAAACATGCAAAGGATGGCAGTTGCTATCATTTCTATCCTGGCTGCCAAGCTTTCTACAGAACAAACT
GCACAGCTTGGTACTGAGCTCTTCATTGTCAGGCAACTTCTTCAAATAGTGAAGCAGAAAACCAATCAAAATTCAGTGGACACTACATTG
AAATTTACTTTGAGTGCACTTTGGAACCTCACAGATGAATCTCCAACCACTTGTAGACACTTTATTGAAAACCAAGGGTTAGAACTCTTC
ATGAGGGTTCTAGAGTCTTTCCCAACTGAGTCATCCATTCAGCAGAAAGTTCTAGGACTTTTGGGTTAATATGATTATTTGATACAGAAG
TTGGCTCAGGTCATCTGAAACGGAAAGAACAATATAGCTGAAGTACAAGAATTACATTCTGAATTAATGTGGAAAGATTTTATAGACCAC
ATCAGTAGTCTCCTACACAGTGTGGAAGTGGAAGTCAGTTACTTTGCAGCTGGAATTATTGCCCATTTAATATCCAGAGGTGAACAAGCT
TGGACATTGAGTCGTAGCCAGAGGAATTCTCTGCTGGATGATTTGCATTCAGCTATTTTGAAATGGCCAACTCCAGAGTGTGAGATGGTA
GCATACAGGTCCTTTAATCCATTTTTCCCATTACTTGGCTGTTTCACAACACCAGGAGTTCAGCTATGGGCAGTTTGGGCCATGCAACAT

>19641_19641_9_CSAD-ZYG11B_CSAD_chr12_53553904_ENST00000453446_ZYG11B_chr1_53222130_ENST00000545132_length(amino acids)=645AA_BP=76
MESPQAPRSRPAMLCTSSPGYLEPAQALPWVPGQLPFPAGQVLRCGSGHGRQGGAVWPPCGLSEAVAHVEGTGRSRAGAAHRPGLCPCPE
EASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVFPQEVADRLLRTMAFHGLLNDGTVGIFRGNQMRLKRACIRKAKISAVAFRKA
FCHHKLVELDATGVNADITITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLESL
DISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTD
KAVEAFIQQRPSMQFVGLLATDAGYSEFLTGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLTHVMEKTKPEILKLVVTGMR
NHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCLLSLCSDRILQDVPFNRFEAAKLVMQWLCNHED
QNMQRMAVAIISILAAKLSTEQTAQLGTELFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVLESF

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CSAD-ZYG11B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CSAD-ZYG11B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CSAD-ZYG11B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCSADC0023893Liver Cirrhosis, Experimental1CTD_human