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Fusion Gene Summary | |
Fusion Gene ORF analysis | |
Fusion Genomic Features | |
Fusion Protein Features | |
Fusion Gene Sequence | |
Fusion Gene PPI analysis | |
Related Drugs | |
Related Diseases |
Fusion gene:PDE9A-DHRS7 (FusionGDB2 ID:HG5152TG51635) |
Fusion Gene Summary for PDE9A-DHRS7 |
Fusion gene summary |
Fusion gene information | Fusion gene name: PDE9A-DHRS7 | Fusion gene ID: hg5152tg51635 | Hgene | Tgene | Gene symbol | PDE9A | DHRS7 | Gene ID | 5152 | 51635 |
Gene name | phosphodiesterase 9A | dehydrogenase/reductase 7 | |
Synonyms | HSPDE9A2 | CGI-86|SDR34C1|retDSR4|retSDR4 | |
Cytomap | ('PDE9A')('DHRS7') 21q22.3 | 14q23.1 | |
Type of gene | protein-coding | protein-coding | |
Description | high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9ACGMP-specific 3',5'-cyclic phosphodiesterase type 9phosphodiesterase PDE9A21 | dehydrogenase/reductase SDR family member 7dehydrogenase/reductase (SDR family) member 7retinal short-chain dehydrogenase/reductase 4short chain dehydrogenase/reductase family 34C member 1 | |
Modification date | 20200327 | 20200313 | |
UniProtAcc | . | . | |
Ensembl transtripts involved in fusion gene | ENST00000470987, ENST00000291539, ENST00000328862, ENST00000335440, ENST00000335512, ENST00000349112, ENST00000380328, ENST00000398224, ENST00000398225, ENST00000398227, ENST00000398229, ENST00000398232, ENST00000398234, ENST00000398236, ENST00000539837, | ||
Fusion gene scores | * DoF score | 11 X 7 X 6=462 | 3 X 2 X 3=18 |
# samples | 11 | 3 | |
** MAII score | log2(11/462*10)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: PDE9A [Title/Abstract] AND DHRS7 [Title/Abstract] AND fusion [Title/Abstract] | ||
Most frequent breakpoint | PDE9A(44153536)-DHRS7(60622870), # samples:3 | ||
Anticipated loss of major functional domain due to fusion event. | PDE9A-DHRS7 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. PDE9A-DHRS7 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Partner | Gene | GO ID | GO term | PubMed ID |
Hgene | PDE9A | GO:0046068 | cGMP metabolic process | 9624146 |
Hgene | PDE9A | GO:0046069 | cGMP catabolic process | 25799991 |
Fusion gene breakpoints across PDE9A (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene breakpoints across DHRS7 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChimerDB4 | LGG | TCGA-HT-7603-01A | PDE9A | chr21 | 44153536 | - | DHRS7 | chr14 | 60622870 | - |
ChimerDB4 | LGG | TCGA-HT-7603-01A | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
ChimerDB4 | LGG | TCGA-HT-7603 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
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Fusion Gene ORF analysis for PDE9A-DHRS7 |
Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
3UTR-3CDS | ENST00000470987 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
3UTR-3CDS | ENST00000470987 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
3UTR-5UTR | ENST00000470987 | ENST00000536410 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
3UTR-intron | ENST00000470987 | ENST00000553986 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-5UTR | ENST00000291539 | ENST00000536410 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-5UTR | ENST00000328862 | ENST00000536410 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-5UTR | ENST00000335440 | ENST00000536410 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-5UTR | ENST00000335512 | ENST00000536410 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-5UTR | ENST00000349112 | ENST00000536410 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-5UTR | ENST00000380328 | ENST00000536410 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-5UTR | ENST00000398224 | ENST00000536410 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-5UTR | ENST00000398225 | ENST00000536410 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-5UTR | ENST00000398227 | ENST00000536410 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-5UTR | ENST00000398229 | ENST00000536410 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-5UTR | ENST00000398232 | ENST00000536410 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-5UTR | ENST00000398234 | ENST00000536410 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-5UTR | ENST00000398236 | ENST00000536410 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-5UTR | ENST00000539837 | ENST00000536410 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-intron | ENST00000291539 | ENST00000553986 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-intron | ENST00000328862 | ENST00000553986 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-intron | ENST00000335440 | ENST00000553986 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-intron | ENST00000335512 | ENST00000553986 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-intron | ENST00000349112 | ENST00000553986 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-intron | ENST00000380328 | ENST00000553986 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-intron | ENST00000398224 | ENST00000553986 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-intron | ENST00000398225 | ENST00000553986 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-intron | ENST00000398227 | ENST00000553986 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-intron | ENST00000398229 | ENST00000553986 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-intron | ENST00000398232 | ENST00000553986 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-intron | ENST00000398234 | ENST00000553986 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-intron | ENST00000398236 | ENST00000553986 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
5CDS-intron | ENST00000539837 | ENST00000553986 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000291539 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000291539 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000328862 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000328862 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000335440 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000335440 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000335512 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000335512 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000349112 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000349112 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000380328 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000380328 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000398224 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000398224 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000398225 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000398225 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000398227 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000398227 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000398229 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000398229 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000398232 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000398232 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000398234 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000398234 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000398236 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000398236 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000539837 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
In-frame | ENST00000539837 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - |
ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
ENST00000335512 | PDE9A | chr21 | 44153536 | + | ENST00000216500 | DHRS7 | chr14 | 60622870 | - | 2186 | 453 | 461 | 1339 | 292 |
ENST00000335512 | PDE9A | chr21 | 44153536 | + | ENST00000557185 | DHRS7 | chr14 | 60622870 | - | 1522 | 453 | 461 | 1339 | 292 |
ENST00000539837 | PDE9A | chr21 | 44153536 | + | ENST00000216500 | DHRS7 | chr14 | 60622870 | - | 2085 | 352 | 360 | 1238 | 292 |
ENST00000539837 | PDE9A | chr21 | 44153536 | + | ENST00000557185 | DHRS7 | chr14 | 60622870 | - | 1421 | 352 | 360 | 1238 | 292 |
ENST00000291539 | PDE9A | chr21 | 44153536 | + | ENST00000216500 | DHRS7 | chr14 | 60622870 | - | 2361 | 628 | 636 | 1514 | 292 |
ENST00000291539 | PDE9A | chr21 | 44153536 | + | ENST00000557185 | DHRS7 | chr14 | 60622870 | - | 1697 | 628 | 636 | 1514 | 292 |
ENST00000398236 | PDE9A | chr21 | 44153536 | + | ENST00000216500 | DHRS7 | chr14 | 60622870 | - | 2079 | 346 | 354 | 1232 | 292 |
ENST00000398236 | PDE9A | chr21 | 44153536 | + | ENST00000557185 | DHRS7 | chr14 | 60622870 | - | 1415 | 346 | 354 | 1232 | 292 |
ENST00000398229 | PDE9A | chr21 | 44153536 | + | ENST00000216500 | DHRS7 | chr14 | 60622870 | - | 1987 | 254 | 262 | 1140 | 292 |
ENST00000398229 | PDE9A | chr21 | 44153536 | + | ENST00000557185 | DHRS7 | chr14 | 60622870 | - | 1323 | 254 | 262 | 1140 | 292 |
ENST00000398234 | PDE9A | chr21 | 44153536 | + | ENST00000216500 | DHRS7 | chr14 | 60622870 | - | 2086 | 353 | 361 | 1239 | 292 |
ENST00000398234 | PDE9A | chr21 | 44153536 | + | ENST00000557185 | DHRS7 | chr14 | 60622870 | - | 1422 | 353 | 361 | 1239 | 292 |
ENST00000398232 | PDE9A | chr21 | 44153536 | + | ENST00000216500 | DHRS7 | chr14 | 60622870 | - | 2188 | 455 | 463 | 1341 | 292 |
ENST00000398232 | PDE9A | chr21 | 44153536 | + | ENST00000557185 | DHRS7 | chr14 | 60622870 | - | 1524 | 455 | 463 | 1341 | 292 |
ENST00000398227 | PDE9A | chr21 | 44153536 | + | ENST00000216500 | DHRS7 | chr14 | 60622870 | - | 1909 | 176 | 184 | 1062 | 292 |
ENST00000398227 | PDE9A | chr21 | 44153536 | + | ENST00000557185 | DHRS7 | chr14 | 60622870 | - | 1245 | 176 | 184 | 1062 | 292 |
ENST00000398225 | PDE9A | chr21 | 44153536 | + | ENST00000216500 | DHRS7 | chr14 | 60622870 | - | 2266 | 533 | 541 | 1419 | 292 |
ENST00000398225 | PDE9A | chr21 | 44153536 | + | ENST00000557185 | DHRS7 | chr14 | 60622870 | - | 1602 | 533 | 541 | 1419 | 292 |
ENST00000380328 | PDE9A | chr21 | 44153536 | + | ENST00000216500 | DHRS7 | chr14 | 60622870 | - | 2178 | 445 | 453 | 1331 | 292 |
ENST00000380328 | PDE9A | chr21 | 44153536 | + | ENST00000557185 | DHRS7 | chr14 | 60622870 | - | 1514 | 445 | 453 | 1331 | 292 |
ENST00000328862 | PDE9A | chr21 | 44153536 | + | ENST00000216500 | DHRS7 | chr14 | 60622870 | - | 2259 | 526 | 534 | 1412 | 292 |
ENST00000328862 | PDE9A | chr21 | 44153536 | + | ENST00000557185 | DHRS7 | chr14 | 60622870 | - | 1595 | 526 | 534 | 1412 | 292 |
ENST00000335440 | PDE9A | chr21 | 44153536 | + | ENST00000216500 | DHRS7 | chr14 | 60622870 | - | 2031 | 298 | 306 | 1184 | 292 |
ENST00000335440 | PDE9A | chr21 | 44153536 | + | ENST00000557185 | DHRS7 | chr14 | 60622870 | - | 1367 | 298 | 306 | 1184 | 292 |
ENST00000398224 | PDE9A | chr21 | 44153536 | + | ENST00000216500 | DHRS7 | chr14 | 60622870 | - | 1974 | 241 | 249 | 1127 | 292 |
ENST00000398224 | PDE9A | chr21 | 44153536 | + | ENST00000557185 | DHRS7 | chr14 | 60622870 | - | 1310 | 241 | 249 | 1127 | 292 |
ENST00000349112 | PDE9A | chr21 | 44153536 | + | ENST00000216500 | DHRS7 | chr14 | 60622870 | - | 1919 | 186 | 194 | 1072 | 292 |
ENST00000349112 | PDE9A | chr21 | 44153536 | + | ENST00000557185 | DHRS7 | chr14 | 60622870 | - | 1255 | 186 | 194 | 1072 | 292 |
DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
ENST00000335512 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.002422206 | 0.99757785 |
ENST00000335512 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.003957223 | 0.99604285 |
ENST00000539837 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.001935626 | 0.99806434 |
ENST00000539837 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.002963294 | 0.9970367 |
ENST00000291539 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.00316381 | 0.9968362 |
ENST00000291539 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.005417369 | 0.9945826 |
ENST00000398236 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.002337817 | 0.9976622 |
ENST00000398236 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.003653681 | 0.9963463 |
ENST00000398229 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.001758029 | 0.998242 |
ENST00000398229 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.002504011 | 0.99749595 |
ENST00000398234 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.002156915 | 0.997843 |
ENST00000398234 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.003409568 | 0.9965905 |
ENST00000398232 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.002881091 | 0.99711895 |
ENST00000398232 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.004545986 | 0.99545395 |
ENST00000398227 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.001653519 | 0.99834645 |
ENST00000398227 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.002231565 | 0.9977684 |
ENST00000398225 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.002903488 | 0.99709654 |
ENST00000398225 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.004874683 | 0.99512535 |
ENST00000380328 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.002024397 | 0.99797565 |
ENST00000380328 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.002947813 | 0.9970522 |
ENST00000328862 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.00294515 | 0.9970548 |
ENST00000328862 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.004811212 | 0.99518883 |
ENST00000335440 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.001895536 | 0.99810445 |
ENST00000335440 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.002724331 | 0.99727565 |
ENST00000398224 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.002284602 | 0.99771535 |
ENST00000398224 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.003243166 | 0.99675685 |
ENST00000349112 | ENST00000216500 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.001911946 | 0.99808806 |
ENST00000349112 | ENST00000557185 | PDE9A | chr21 | 44153536 | + | DHRS7 | chr14 | 60622870 | - | 0.002701378 | 0.99729866 |
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Fusion Genomic Features for PDE9A-DHRS7 |
FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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Fusion Protein Features for PDE9A-DHRS7 |
Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr21:44153536/chr14:60622870) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
Main function of each fusion partner protein. (from UniProt) |
Hgene | Tgene |
. | . |
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Tgene | DHRS7 | chr21:44153536 | chr14:60622870 | ENST00000216500 | 1 | 8 | 54_78 | 44 | 340.0 | Nucleotide binding | NAD | |
Tgene | DHRS7 | chr21:44153536 | chr14:60622870 | ENST00000536410 | 0 | 7 | 54_78 | 0 | 290.0 | Nucleotide binding | NAD | |
Tgene | DHRS7 | chr21:44153536 | chr14:60622870 | ENST00000557185 | 0 | 7 | 54_78 | 44 | 340.0 | Nucleotide binding | NAD |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000291539 | + | 7 | 20 | 236_557 | 189 | 594.0 | Domain | PDEase |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000328862 | + | 6 | 19 | 236_557 | 163 | 568.0 | Domain | PDEase |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000335440 | + | 4 | 17 | 236_557 | 87 | 492.0 | Domain | PDEase |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000335512 | + | 6 | 19 | 236_557 | 129 | 534.0 | Domain | PDEase |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000349112 | + | 3 | 16 | 236_557 | 61 | 466.0 | Domain | PDEase |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000380328 | + | 6 | 19 | 236_557 | 136 | 541.0 | Domain | PDEase |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398224 | + | 4 | 17 | 236_557 | 62 | 467.0 | Domain | PDEase |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398225 | + | 6 | 19 | 236_557 | 148 | 553.0 | Domain | PDEase |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398227 | + | 2 | 15 | 236_557 | 29 | 434.0 | Domain | PDEase |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398229 | + | 3 | 16 | 236_557 | 55 | 460.0 | Domain | PDEase |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398232 | + | 5 | 18 | 236_557 | 122 | 527.0 | Domain | PDEase |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398234 | + | 5 | 18 | 236_557 | 88 | 493.0 | Domain | PDEase |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398236 | + | 5 | 18 | 236_557 | 103 | 508.0 | Domain | PDEase |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000291539 | + | 7 | 20 | 312_316 | 189 | 594.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000291539 | + | 7 | 20 | 512_513 | 189 | 594.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000328862 | + | 6 | 19 | 312_316 | 163 | 568.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000328862 | + | 6 | 19 | 512_513 | 163 | 568.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000335440 | + | 4 | 17 | 312_316 | 87 | 492.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000335440 | + | 4 | 17 | 512_513 | 87 | 492.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000335512 | + | 6 | 19 | 312_316 | 129 | 534.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000335512 | + | 6 | 19 | 512_513 | 129 | 534.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000349112 | + | 3 | 16 | 312_316 | 61 | 466.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000349112 | + | 3 | 16 | 512_513 | 61 | 466.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000380328 | + | 6 | 19 | 312_316 | 136 | 541.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000380328 | + | 6 | 19 | 512_513 | 136 | 541.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398224 | + | 4 | 17 | 312_316 | 62 | 467.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398224 | + | 4 | 17 | 512_513 | 62 | 467.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398225 | + | 6 | 19 | 312_316 | 148 | 553.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398225 | + | 6 | 19 | 512_513 | 148 | 553.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398227 | + | 2 | 15 | 312_316 | 29 | 434.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398227 | + | 2 | 15 | 512_513 | 29 | 434.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398229 | + | 3 | 16 | 312_316 | 55 | 460.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398229 | + | 3 | 16 | 512_513 | 55 | 460.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398232 | + | 5 | 18 | 312_316 | 122 | 527.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398232 | + | 5 | 18 | 512_513 | 122 | 527.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398234 | + | 5 | 18 | 312_316 | 88 | 493.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398234 | + | 5 | 18 | 512_513 | 88 | 493.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398236 | + | 5 | 18 | 312_316 | 103 | 508.0 | Nucleotide binding | 3'%2C5'-cGMP |
Hgene | PDE9A | chr21:44153536 | chr14:60622870 | ENST00000398236 | + | 5 | 18 | 512_513 | 103 | 508.0 | Nucleotide binding | 3'%2C5'-cGMP |
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Fusion Gene Sequence for PDE9A-DHRS7 |
For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
>63816_63816_1_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000291539_DHRS7_chr14_60622870_ENST00000216500_length(transcript)=2361nt_BP=628nt CGCGGCGGCTGGCGTCGGGAAAGTACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCC AAGGCCATCTACCTGGACATCGATGGACGCATTCAGAAGGTAATCTTCAGCAAGTACTGCAACTCCAGCGACATCATGGACCTGTTCTGC ATCGCCACCGGCCTGCCTCGGAACACGACCATCTCCCTGCTGACCACCGACGACGCCATGGTCTCCATCGACCCCACCATGCCCGCGAAT TCAGAACGCACTCCGTACAAAGTGAGACCTGTGGCCATCAAGCAACTCTCCGCTGGTGTCGAGGACAAGAGAACCACAAGCCGTGGCCAG TCTGCTGAGAGACCACTGAGGGACAGACGGGTTGTGGGCCTGGAGCAGCCCCGGAGGGAAGGAGCATTTGAAAGTGGACAGGTAGAGCCC AGGCCCAGAGAGCCCCAGGGCTGCTACCAGGAAGGCCAGCGCATCCCTCCAGAGAGAGAAGAATTAATCCAGAGCGTGCTGGCGCAGGTT GCAGAGCAGTTCTCAAGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAA TGGGAGCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTT TCTCTTGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATA CTTGTTTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTG GTCAACAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGG ACGGTGTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATA TCTGTACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCA GGTATAATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGC AATAATGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGG ATCTCAGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAA AGGATTGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTAC TTTTCAAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTAC TTTTTAATAGATATGACTTTGCTTCCAACATGGAATGAAATAAAAAATAAATAATAAAAGATTGCCATGAATCTTGCAAAAAAGGTATTA ACTCATACTATATTCTTGGATAAAATAACCTTTTAAAATACTTTAGCACATATGCTTAAAATCTAAGTTAACAGATTTGTCTTAGTCCAT TTGTGCTGCTATAACAAAATACCACAGATTTGGTAATTTATAAACAACAGAAATCTGTTTTTCCTGGCTCTTGAGGCTGGGAATTCCAAG ACCAATGCACCAGCAGAATTAGTGTCTGGTGAAGGCTGATCTCTGCTTCCAAGATGGCACCTCATTGCTGCATCCTCCACAGTGGAGGAA TGTATGTCCTCACATGGTGGAAGGGACAGAAGGGAAAGAGGAGCAAAATGCTTTCAAAAGAGCATTTAATCTCATTCATTACTCAGTCAC CTCTTAAAGGCCACATCCTTTAATACTGTTGCTTTGGGGATTAAGTTTCGACATGAATTTTGGAGGGGACAAAAACATCCAAACCATAGC AACATAAATGTATAGAATATTTCACACAAAGCAGAGTGCTGGGTAATGACCAGATATAAAGAAGTATTTGAAATGACCTTACCTCCAAGA TGCTTATACTCTTAGAAAAGTTGACAGGTACAGATGGCTGTAATTTGAAGCAGCAGGTAGGATTCATTGCACCTATTATTCATTAAACAC >63816_63816_1_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000291539_DHRS7_chr14_60622870_ENST00000216500_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_2_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000291539_DHRS7_chr14_60622870_ENST00000557185_length(transcript)=1697nt_BP=628nt CGCGGCGGCTGGCGTCGGGAAAGTACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCC AAGGCCATCTACCTGGACATCGATGGACGCATTCAGAAGGTAATCTTCAGCAAGTACTGCAACTCCAGCGACATCATGGACCTGTTCTGC ATCGCCACCGGCCTGCCTCGGAACACGACCATCTCCCTGCTGACCACCGACGACGCCATGGTCTCCATCGACCCCACCATGCCCGCGAAT TCAGAACGCACTCCGTACAAAGTGAGACCTGTGGCCATCAAGCAACTCTCCGCTGGTGTCGAGGACAAGAGAACCACAAGCCGTGGCCAG TCTGCTGAGAGACCACTGAGGGACAGACGGGTTGTGGGCCTGGAGCAGCCCCGGAGGGAAGGAGCATTTGAAAGTGGACAGGTAGAGCCC AGGCCCAGAGAGCCCCAGGGCTGCTACCAGGAAGGCCAGCGCATCCCTCCAGAGAGAGAAGAATTAATCCAGAGCGTGCTGGCGCAGGTT GCAGAGCAGTTCTCAAGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAA TGGGAGCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTT TCTCTTGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATA CTTGTTTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTG GTCAACAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGG ACGGTGTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATA TCTGTACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCA GGTATAATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGC AATAATGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGG ATCTCAGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAA AGGATTGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTAC TTTTCAAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTAC >63816_63816_2_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000291539_DHRS7_chr14_60622870_ENST00000557185_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_3_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000328862_DHRS7_chr14_60622870_ENST00000216500_length(transcript)=2259nt_BP=526nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGGTAATCTTCAGCAAGTACTGCAACTCCAGCGACATCATGGACCTGTTCTGCATCGCCACCGGCCTGCCTCGCACT CCGTACAAAGTGAGACCTGTGGCCATCAAGCAACTCTCCGCTGGTGTCGAGGACAAGAGAACCACAAGCCGTGGCCAGTCTGCTGAGAGA CCACTGAGGGACAGACGGGTTGTGGGCCTGGAGCAGCCCCGGAGGGAAGGAGCATTTGAAAGTGGACAGGTAGAGCCCAGGCCCAGAGAG CCCCAGGGCTGCTACCAGGAAGGCCAGCGCATCCCTCCAGAGAGAGAAGAATTAATCCAGAGCGTGCTGGCGCAGGTTGCAGAGCAGTTC TCAAGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATGGGAGCTGACT GATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTCTCTTGTGCTG TCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACTTGTTTTGCCC CTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGTCAACAATGGT GGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGACGGTGTCCTTG ACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATCTGTACCTCTT TCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGGTATAATAGTT TCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAATAATGGAGAC CAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGATCTCAGAACAA CCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAGGATTGAGAAC TTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTTTTCAAGCCAC TGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTTTTTAATAGAT ATGACTTTGCTTCCAACATGGAATGAAATAAAAAATAAATAATAAAAGATTGCCATGAATCTTGCAAAAAAGGTATTAACTCATACTATA TTCTTGGATAAAATAACCTTTTAAAATACTTTAGCACATATGCTTAAAATCTAAGTTAACAGATTTGTCTTAGTCCATTTGTGCTGCTAT AACAAAATACCACAGATTTGGTAATTTATAAACAACAGAAATCTGTTTTTCCTGGCTCTTGAGGCTGGGAATTCCAAGACCAATGCACCA GCAGAATTAGTGTCTGGTGAAGGCTGATCTCTGCTTCCAAGATGGCACCTCATTGCTGCATCCTCCACAGTGGAGGAATGTATGTCCTCA CATGGTGGAAGGGACAGAAGGGAAAGAGGAGCAAAATGCTTTCAAAAGAGCATTTAATCTCATTCATTACTCAGTCACCTCTTAAAGGCC ACATCCTTTAATACTGTTGCTTTGGGGATTAAGTTTCGACATGAATTTTGGAGGGGACAAAAACATCCAAACCATAGCAACATAAATGTA TAGAATATTTCACACAAAGCAGAGTGCTGGGTAATGACCAGATATAAAGAAGTATTTGAAATGACCTTACCTCCAAGATGCTTATACTCT TAGAAAAGTTGACAGGTACAGATGGCTGTAATTTGAAGCAGCAGGTAGGATTCATTGCACCTATTATTCATTAAACACCTGTTGTATGTC >63816_63816_3_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000328862_DHRS7_chr14_60622870_ENST00000216500_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_4_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000328862_DHRS7_chr14_60622870_ENST00000557185_length(transcript)=1595nt_BP=526nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGGTAATCTTCAGCAAGTACTGCAACTCCAGCGACATCATGGACCTGTTCTGCATCGCCACCGGCCTGCCTCGCACT CCGTACAAAGTGAGACCTGTGGCCATCAAGCAACTCTCCGCTGGTGTCGAGGACAAGAGAACCACAAGCCGTGGCCAGTCTGCTGAGAGA CCACTGAGGGACAGACGGGTTGTGGGCCTGGAGCAGCCCCGGAGGGAAGGAGCATTTGAAAGTGGACAGGTAGAGCCCAGGCCCAGAGAG CCCCAGGGCTGCTACCAGGAAGGCCAGCGCATCCCTCCAGAGAGAGAAGAATTAATCCAGAGCGTGCTGGCGCAGGTTGCAGAGCAGTTC TCAAGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATGGGAGCTGACT GATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTCTCTTGTGCTG TCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACTTGTTTTGCCC CTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGTCAACAATGGT GGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGACGGTGTCCTTG ACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATCTGTACCTCTT TCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGGTATAATAGTT TCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAATAATGGAGAC CAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGATCTCAGAACAA CCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAGGATTGAGAAC TTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTTTTCAAGCCAC TGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTTTTTAATAGAT >63816_63816_4_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000328862_DHRS7_chr14_60622870_ENST00000557185_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_5_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000335440_DHRS7_chr14_60622870_ENST00000216500_length(transcript)=2031nt_BP=298nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGGAACACGACCATCTCCCTGCTGACCACCGACGACGCCATGGTCTCCATCGACCCCACCATGCCCGCGAATTCAGA ACGCACTCCGTACAAAGTGAGACCTGTGGCCATCAAGCAACTCTCCGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCAC TTGGCTGTCCTAGAGAAACGCGTGGAATAATGGGAGCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAG CTGGCTTACCAGTTGTCTAAACTAGGAGTTTCTCTTGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTA GAGAATGGCAATTTAAAAGAAAAAGATATACTTGTTTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTT CTCCAGGAGTTTGGTAGAATCGACATTCTGGTCAACAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTAC AGAAAGCTAATAGAGCTTAACTACTTAGGGACGGTGTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATT GTTACTGTGAATAGCATCCTGGGTATCATATCTGTACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAAT GGCCTTCGAACAGAACTTGCCACATACCCAGGTATAATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCC CTAGCTGGAGAAGTCACAAAGACTATAGGCAATAATGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATC AGCATGGCCAATGATTTGAAAGAAGTTTGGATCTCAGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCC TGGTGGATAACCAACAAGATGGGGAAGAAAAGGATTGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAG ACAAAACATGACTGAAAAGAGCACCTGTACTTTTCAAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCT GAATAATCAAAGACTAATTTGTGATTTTACTTTTTAATAGATATGACTTTGCTTCCAACATGGAATGAAATAAAAAATAAATAATAAAAG ATTGCCATGAATCTTGCAAAAAAGGTATTAACTCATACTATATTCTTGGATAAAATAACCTTTTAAAATACTTTAGCACATATGCTTAAA ATCTAAGTTAACAGATTTGTCTTAGTCCATTTGTGCTGCTATAACAAAATACCACAGATTTGGTAATTTATAAACAACAGAAATCTGTTT TTCCTGGCTCTTGAGGCTGGGAATTCCAAGACCAATGCACCAGCAGAATTAGTGTCTGGTGAAGGCTGATCTCTGCTTCCAAGATGGCAC CTCATTGCTGCATCCTCCACAGTGGAGGAATGTATGTCCTCACATGGTGGAAGGGACAGAAGGGAAAGAGGAGCAAAATGCTTTCAAAAG AGCATTTAATCTCATTCATTACTCAGTCACCTCTTAAAGGCCACATCCTTTAATACTGTTGCTTTGGGGATTAAGTTTCGACATGAATTT TGGAGGGGACAAAAACATCCAAACCATAGCAACATAAATGTATAGAATATTTCACACAAAGCAGAGTGCTGGGTAATGACCAGATATAAA GAAGTATTTGAAATGACCTTACCTCCAAGATGCTTATACTCTTAGAAAAGTTGACAGGTACAGATGGCTGTAATTTGAAGCAGCAGGTAG >63816_63816_5_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000335440_DHRS7_chr14_60622870_ENST00000216500_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_6_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000335440_DHRS7_chr14_60622870_ENST00000557185_length(transcript)=1367nt_BP=298nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGGAACACGACCATCTCCCTGCTGACCACCGACGACGCCATGGTCTCCATCGACCCCACCATGCCCGCGAATTCAGA ACGCACTCCGTACAAAGTGAGACCTGTGGCCATCAAGCAACTCTCCGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCAC TTGGCTGTCCTAGAGAAACGCGTGGAATAATGGGAGCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAG CTGGCTTACCAGTTGTCTAAACTAGGAGTTTCTCTTGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTA GAGAATGGCAATTTAAAAGAAAAAGATATACTTGTTTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTT CTCCAGGAGTTTGGTAGAATCGACATTCTGGTCAACAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTAC AGAAAGCTAATAGAGCTTAACTACTTAGGGACGGTGTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATT GTTACTGTGAATAGCATCCTGGGTATCATATCTGTACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAAT GGCCTTCGAACAGAACTTGCCACATACCCAGGTATAATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCC CTAGCTGGAGAAGTCACAAAGACTATAGGCAATAATGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATC AGCATGGCCAATGATTTGAAAGAAGTTTGGATCTCAGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCC TGGTGGATAACCAACAAGATGGGGAAGAAAAGGATTGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAG ACAAAACATGACTGAAAAGAGCACCTGTACTTTTCAAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCT GAATAATCAAAGACTAATTTGTGATTTTACTTTTTAATAGATATGACTTTGCTTCCAACATGGAATGAAATAAAAAATAAATAATAAAAG >63816_63816_6_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000335440_DHRS7_chr14_60622870_ENST00000557185_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_7_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000335512_DHRS7_chr14_60622870_ENST00000216500_length(transcript)=2186nt_BP=453nt CCTCCCGCGGCGGCTGGCGTCGGGAAAGTACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACC GGCCCAAGGCCATCTACCTGGACATCGATGGACGCATTCAGAAGGTAATCTTCAGCAAGTACTGCAACTCCAGCGACATCATGGACCTGT TCTGCATCGCCACCGGCCTGCCTCGGAACACGACCATCTCCCTGCTGACCACCGACGACGCCATGGTCTCCATCGACCCCACCATGCCCG CGAATTCAGAACGCACTCCGTACAAAGTGAGACCTGTGGCCATCAAGCAACTCTCCGAGAGAGAAGAATTAATCCAGAGCGTGCTGGCGC AGGTTGCAGAGCAGTTCTCAAGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGG AATAATGGGAGCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAG GAGTTTCTCTTGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAG ATATACTTGTTTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACA TTCTGGTCAACAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACT TAGGGACGGTGTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTA TCATATCTGTACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACAT ACCCAGGTATAATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTA TAGGCAATAATGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAG TTTGGATCTCAGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGA AGAAAAGGATTGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACC TGTACTTTTCAAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGAT TTTACTTTTTAATAGATATGACTTTGCTTCCAACATGGAATGAAATAAAAAATAAATAATAAAAGATTGCCATGAATCTTGCAAAAAAGG TATTAACTCATACTATATTCTTGGATAAAATAACCTTTTAAAATACTTTAGCACATATGCTTAAAATCTAAGTTAACAGATTTGTCTTAG TCCATTTGTGCTGCTATAACAAAATACCACAGATTTGGTAATTTATAAACAACAGAAATCTGTTTTTCCTGGCTCTTGAGGCTGGGAATT CCAAGACCAATGCACCAGCAGAATTAGTGTCTGGTGAAGGCTGATCTCTGCTTCCAAGATGGCACCTCATTGCTGCATCCTCCACAGTGG AGGAATGTATGTCCTCACATGGTGGAAGGGACAGAAGGGAAAGAGGAGCAAAATGCTTTCAAAAGAGCATTTAATCTCATTCATTACTCA GTCACCTCTTAAAGGCCACATCCTTTAATACTGTTGCTTTGGGGATTAAGTTTCGACATGAATTTTGGAGGGGACAAAAACATCCAAACC ATAGCAACATAAATGTATAGAATATTTCACACAAAGCAGAGTGCTGGGTAATGACCAGATATAAAGAAGTATTTGAAATGACCTTACCTC CAAGATGCTTATACTCTTAGAAAAGTTGACAGGTACAGATGGCTGTAATTTGAAGCAGCAGGTAGGATTCATTGCACCTATTATTCATTA >63816_63816_7_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000335512_DHRS7_chr14_60622870_ENST00000216500_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_8_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000335512_DHRS7_chr14_60622870_ENST00000557185_length(transcript)=1522nt_BP=453nt CCTCCCGCGGCGGCTGGCGTCGGGAAAGTACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACC GGCCCAAGGCCATCTACCTGGACATCGATGGACGCATTCAGAAGGTAATCTTCAGCAAGTACTGCAACTCCAGCGACATCATGGACCTGT TCTGCATCGCCACCGGCCTGCCTCGGAACACGACCATCTCCCTGCTGACCACCGACGACGCCATGGTCTCCATCGACCCCACCATGCCCG CGAATTCAGAACGCACTCCGTACAAAGTGAGACCTGTGGCCATCAAGCAACTCTCCGAGAGAGAAGAATTAATCCAGAGCGTGCTGGCGC AGGTTGCAGAGCAGTTCTCAAGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGG AATAATGGGAGCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAG GAGTTTCTCTTGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAG ATATACTTGTTTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACA TTCTGGTCAACAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACT TAGGGACGGTGTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTA TCATATCTGTACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACAT ACCCAGGTATAATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTA TAGGCAATAATGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAG TTTGGATCTCAGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGA AGAAAAGGATTGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACC TGTACTTTTCAAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGAT >63816_63816_8_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000335512_DHRS7_chr14_60622870_ENST00000557185_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_9_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000349112_DHRS7_chr14_60622870_ENST00000216500_length(transcript)=1919nt_BP=186nt GGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGATGGACGCATTCAGAAGCACTCCGTACAAAGTGAGA CCTGTGGCCATCAAGCAACTCTCCGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCG TGGAATAATGGGAGCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAAC TAGGAGTTTCTCTTGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAA AAGATATACTTGTTTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCG ACATTCTGGTCAACAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACT ACTTAGGGACGGTGTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGG GTATCATATCTGTACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCA CATACCCAGGTATAATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGA CTATAGGCAATAATGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAG AAGTTTGGATCTCAGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGG GGAAGAAAAGGATTGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGC ACCTGTACTTTTCAAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGT GATTTTACTTTTTAATAGATATGACTTTGCTTCCAACATGGAATGAAATAAAAAATAAATAATAAAAGATTGCCATGAATCTTGCAAAAA AGGTATTAACTCATACTATATTCTTGGATAAAATAACCTTTTAAAATACTTTAGCACATATGCTTAAAATCTAAGTTAACAGATTTGTCT TAGTCCATTTGTGCTGCTATAACAAAATACCACAGATTTGGTAATTTATAAACAACAGAAATCTGTTTTTCCTGGCTCTTGAGGCTGGGA ATTCCAAGACCAATGCACCAGCAGAATTAGTGTCTGGTGAAGGCTGATCTCTGCTTCCAAGATGGCACCTCATTGCTGCATCCTCCACAG TGGAGGAATGTATGTCCTCACATGGTGGAAGGGACAGAAGGGAAAGAGGAGCAAAATGCTTTCAAAAGAGCATTTAATCTCATTCATTAC TCAGTCACCTCTTAAAGGCCACATCCTTTAATACTGTTGCTTTGGGGATTAAGTTTCGACATGAATTTTGGAGGGGACAAAAACATCCAA ACCATAGCAACATAAATGTATAGAATATTTCACACAAAGCAGAGTGCTGGGTAATGACCAGATATAAAGAAGTATTTGAAATGACCTTAC CTCCAAGATGCTTATACTCTTAGAAAAGTTGACAGGTACAGATGGCTGTAATTTGAAGCAGCAGGTAGGATTCATTGCACCTATTATTCA >63816_63816_9_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000349112_DHRS7_chr14_60622870_ENST00000216500_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_10_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000349112_DHRS7_chr14_60622870_ENST00000557185_length(transcript)=1255nt_BP=186nt GGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGATGGACGCATTCAGAAGCACTCCGTACAAAGTGAGA CCTGTGGCCATCAAGCAACTCTCCGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCG TGGAATAATGGGAGCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAAC TAGGAGTTTCTCTTGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAA AAGATATACTTGTTTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCG ACATTCTGGTCAACAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACT ACTTAGGGACGGTGTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGG GTATCATATCTGTACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCA CATACCCAGGTATAATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGA CTATAGGCAATAATGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAG AAGTTTGGATCTCAGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGG GGAAGAAAAGGATTGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGC ACCTGTACTTTTCAAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGT >63816_63816_10_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000349112_DHRS7_chr14_60622870_ENST00000557185_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_11_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000380328_DHRS7_chr14_60622870_ENST00000216500_length(transcript)=2178nt_BP=445nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGGTAATCTTCAGCAAGTACTGCAACTCCAGCGACATCATGGACCTGTTCTGCATCGCCACCGGCCTGCCTCGGAAC ACGACCATCTCCCTGCTGACCACCGACGACGCCATGGTCTCCATCGACCCCACCATGCCCGCGAATTCAGAACGGAATGAGCTCATTCTC TATACATCACTCCGTAACTTGTTGTTTTTACCTAGTAAGGAGTCATGGGCGTCCCACCAGCACTCCGTACAAAGTGAGACCTGTGGCCAT CAAGCAACTCTCCGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATGG GAGCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTCT CTTGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACTT GTTTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGTC AACAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGACG GTGTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATCT GTACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGGT ATAATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAAT AATGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGATC TCAGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAGG ATTGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTTT TCAAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTTT TTAATAGATATGACTTTGCTTCCAACATGGAATGAAATAAAAAATAAATAATAAAAGATTGCCATGAATCTTGCAAAAAAGGTATTAACT CATACTATATTCTTGGATAAAATAACCTTTTAAAATACTTTAGCACATATGCTTAAAATCTAAGTTAACAGATTTGTCTTAGTCCATTTG TGCTGCTATAACAAAATACCACAGATTTGGTAATTTATAAACAACAGAAATCTGTTTTTCCTGGCTCTTGAGGCTGGGAATTCCAAGACC AATGCACCAGCAGAATTAGTGTCTGGTGAAGGCTGATCTCTGCTTCCAAGATGGCACCTCATTGCTGCATCCTCCACAGTGGAGGAATGT ATGTCCTCACATGGTGGAAGGGACAGAAGGGAAAGAGGAGCAAAATGCTTTCAAAAGAGCATTTAATCTCATTCATTACTCAGTCACCTC TTAAAGGCCACATCCTTTAATACTGTTGCTTTGGGGATTAAGTTTCGACATGAATTTTGGAGGGGACAAAAACATCCAAACCATAGCAAC ATAAATGTATAGAATATTTCACACAAAGCAGAGTGCTGGGTAATGACCAGATATAAAGAAGTATTTGAAATGACCTTACCTCCAAGATGC TTATACTCTTAGAAAAGTTGACAGGTACAGATGGCTGTAATTTGAAGCAGCAGGTAGGATTCATTGCACCTATTATTCATTAAACACCTG >63816_63816_11_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000380328_DHRS7_chr14_60622870_ENST00000216500_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_12_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000380328_DHRS7_chr14_60622870_ENST00000557185_length(transcript)=1514nt_BP=445nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGGTAATCTTCAGCAAGTACTGCAACTCCAGCGACATCATGGACCTGTTCTGCATCGCCACCGGCCTGCCTCGGAAC ACGACCATCTCCCTGCTGACCACCGACGACGCCATGGTCTCCATCGACCCCACCATGCCCGCGAATTCAGAACGGAATGAGCTCATTCTC TATACATCACTCCGTAACTTGTTGTTTTTACCTAGTAAGGAGTCATGGGCGTCCCACCAGCACTCCGTACAAAGTGAGACCTGTGGCCAT CAAGCAACTCTCCGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATGG GAGCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTCT CTTGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACTT GTTTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGTC AACAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGACG GTGTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATCT GTACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGGT ATAATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAAT AATGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGATC TCAGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAGG ATTGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTTT TCAAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTTT >63816_63816_12_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000380328_DHRS7_chr14_60622870_ENST00000557185_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_13_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398224_DHRS7_chr14_60622870_ENST00000216500_length(transcript)=1974nt_BP=241nt GGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGATGGACGCATTCAGAAGCACTCCGTACAAAGTGAGA CCTGTGGCCATCAAGCAACTCTCCGAGAGAGAAGAATTAATCCAGAGCGTGCTGGCGCAGGTTGCAGAGCAGTTCTCAAGAGCATTCAAA ATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATGGGAGCTGACTGATATGGTGGTGTGG GTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTCTCTTGTGCTGTCAGCCAGAAGAGTG CATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACTTGTTTTGCCCCTTGACCTGACCGAC ACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGTCAACAATGGTGGAATGTCCCAGCGT TCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGACGGTGTCCTTGACAAAATGTGTTCTG CCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATCTGTACCTCTTTCCATTGGATACTGT GCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGGTATAATAGTTTCTAACATTTGCCCA GGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAATAATGGAGACCAGTCCCACAAGATG ACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGATCTCAGAACAACCTTTCTTGTTAGTA ACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAGGATTGAGAACTTTAAGAGTGGTGTG GATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTTTTCAAGCCACTGGAGGGAGAAATGG AAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTTTTTAATAGATATGACTTTGCTTCCA ACATGGAATGAAATAAAAAATAAATAATAAAAGATTGCCATGAATCTTGCAAAAAAGGTATTAACTCATACTATATTCTTGGATAAAATA ACCTTTTAAAATACTTTAGCACATATGCTTAAAATCTAAGTTAACAGATTTGTCTTAGTCCATTTGTGCTGCTATAACAAAATACCACAG ATTTGGTAATTTATAAACAACAGAAATCTGTTTTTCCTGGCTCTTGAGGCTGGGAATTCCAAGACCAATGCACCAGCAGAATTAGTGTCT GGTGAAGGCTGATCTCTGCTTCCAAGATGGCACCTCATTGCTGCATCCTCCACAGTGGAGGAATGTATGTCCTCACATGGTGGAAGGGAC AGAAGGGAAAGAGGAGCAAAATGCTTTCAAAAGAGCATTTAATCTCATTCATTACTCAGTCACCTCTTAAAGGCCACATCCTTTAATACT GTTGCTTTGGGGATTAAGTTTCGACATGAATTTTGGAGGGGACAAAAACATCCAAACCATAGCAACATAAATGTATAGAATATTTCACAC AAAGCAGAGTGCTGGGTAATGACCAGATATAAAGAAGTATTTGAAATGACCTTACCTCCAAGATGCTTATACTCTTAGAAAAGTTGACAG >63816_63816_13_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398224_DHRS7_chr14_60622870_ENST00000216500_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_14_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398224_DHRS7_chr14_60622870_ENST00000557185_length(transcript)=1310nt_BP=241nt GGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGATGGACGCATTCAGAAGCACTCCGTACAAAGTGAGA CCTGTGGCCATCAAGCAACTCTCCGAGAGAGAAGAATTAATCCAGAGCGTGCTGGCGCAGGTTGCAGAGCAGTTCTCAAGAGCATTCAAA ATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATGGGAGCTGACTGATATGGTGGTGTGG GTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTCTCTTGTGCTGTCAGCCAGAAGAGTG CATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACTTGTTTTGCCCCTTGACCTGACCGAC ACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGTCAACAATGGTGGAATGTCCCAGCGT TCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGACGGTGTCCTTGACAAAATGTGTTCTG CCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATCTGTACCTCTTTCCATTGGATACTGT GCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGGTATAATAGTTTCTAACATTTGCCCA GGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAATAATGGAGACCAGTCCCACAAGATG ACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGATCTCAGAACAACCTTTCTTGTTAGTA ACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAGGATTGAGAACTTTAAGAGTGGTGTG GATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTTTTCAAGCCACTGGAGGGAGAAATGG AAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTTTTTAATAGATATGACTTTGCTTCCA >63816_63816_14_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398224_DHRS7_chr14_60622870_ENST00000557185_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_15_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398225_DHRS7_chr14_60622870_ENST00000216500_length(transcript)=2266nt_BP=533nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGGAACACGACCATCTCCCTGCTGACCACCGACGACGCCATGGTCTCCATCGACCCCACCATGCCCGCGAATTCAGA ACGCACTCCGTACAAAGTGAGACCTGTGGCCATCAAGCAACTCTCCGCTGGTGTCGAGGACAAGAGAACCACAAGCCGTGGCCAGTCTGC TGAGAGACCACTGAGGGACAGACGGGTTGTGGGCCTGGAGCAGCCCCGGAGGGAAGGAGCATTTGAAAGTGGACAGGTAGAGCCCAGGCC CAGAGAGCCCCAGGGCTGCTACCAGGAAGGCCAGCGCATCCCTCCAGAGAGAGAAGAATTAATCCAGAGCGTGCTGGCGCAGGTTGCAGA GCAGTTCTCAAGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATGGGA GCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTCTCT TGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACTTGT TTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGTCAA CAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGACGGT GTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATCTGT ACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGGTAT AATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAATAA TGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGATCTC AGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAGGAT TGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTTTTC AAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTTTTT AATAGATATGACTTTGCTTCCAACATGGAATGAAATAAAAAATAAATAATAAAAGATTGCCATGAATCTTGCAAAAAAGGTATTAACTCA TACTATATTCTTGGATAAAATAACCTTTTAAAATACTTTAGCACATATGCTTAAAATCTAAGTTAACAGATTTGTCTTAGTCCATTTGTG CTGCTATAACAAAATACCACAGATTTGGTAATTTATAAACAACAGAAATCTGTTTTTCCTGGCTCTTGAGGCTGGGAATTCCAAGACCAA TGCACCAGCAGAATTAGTGTCTGGTGAAGGCTGATCTCTGCTTCCAAGATGGCACCTCATTGCTGCATCCTCCACAGTGGAGGAATGTAT GTCCTCACATGGTGGAAGGGACAGAAGGGAAAGAGGAGCAAAATGCTTTCAAAAGAGCATTTAATCTCATTCATTACTCAGTCACCTCTT AAAGGCCACATCCTTTAATACTGTTGCTTTGGGGATTAAGTTTCGACATGAATTTTGGAGGGGACAAAAACATCCAAACCATAGCAACAT AAATGTATAGAATATTTCACACAAAGCAGAGTGCTGGGTAATGACCAGATATAAAGAAGTATTTGAAATGACCTTACCTCCAAGATGCTT ATACTCTTAGAAAAGTTGACAGGTACAGATGGCTGTAATTTGAAGCAGCAGGTAGGATTCATTGCACCTATTATTCATTAAACACCTGTT >63816_63816_15_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398225_DHRS7_chr14_60622870_ENST00000216500_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_16_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398225_DHRS7_chr14_60622870_ENST00000557185_length(transcript)=1602nt_BP=533nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGGAACACGACCATCTCCCTGCTGACCACCGACGACGCCATGGTCTCCATCGACCCCACCATGCCCGCGAATTCAGA ACGCACTCCGTACAAAGTGAGACCTGTGGCCATCAAGCAACTCTCCGCTGGTGTCGAGGACAAGAGAACCACAAGCCGTGGCCAGTCTGC TGAGAGACCACTGAGGGACAGACGGGTTGTGGGCCTGGAGCAGCCCCGGAGGGAAGGAGCATTTGAAAGTGGACAGGTAGAGCCCAGGCC CAGAGAGCCCCAGGGCTGCTACCAGGAAGGCCAGCGCATCCCTCCAGAGAGAGAAGAATTAATCCAGAGCGTGCTGGCGCAGGTTGCAGA GCAGTTCTCAAGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATGGGA GCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTCTCT TGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACTTGT TTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGTCAA CAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGACGGT GTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATCTGT ACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGGTAT AATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAATAA TGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGATCTC AGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAGGAT TGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTTTTC AAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTTTTT >63816_63816_16_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398225_DHRS7_chr14_60622870_ENST00000557185_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_17_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398227_DHRS7_chr14_60622870_ENST00000216500_length(transcript)=1909nt_BP=176nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATG GGAGCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTC TCTTGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACT TGTTTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGT CAACAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGAC GGTGTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATC TGTACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGG TATAATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAA TAATGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGAT CTCAGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAG GATTGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTT TTCAAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTT TTTAATAGATATGACTTTGCTTCCAACATGGAATGAAATAAAAAATAAATAATAAAAGATTGCCATGAATCTTGCAAAAAAGGTATTAAC TCATACTATATTCTTGGATAAAATAACCTTTTAAAATACTTTAGCACATATGCTTAAAATCTAAGTTAACAGATTTGTCTTAGTCCATTT GTGCTGCTATAACAAAATACCACAGATTTGGTAATTTATAAACAACAGAAATCTGTTTTTCCTGGCTCTTGAGGCTGGGAATTCCAAGAC CAATGCACCAGCAGAATTAGTGTCTGGTGAAGGCTGATCTCTGCTTCCAAGATGGCACCTCATTGCTGCATCCTCCACAGTGGAGGAATG TATGTCCTCACATGGTGGAAGGGACAGAAGGGAAAGAGGAGCAAAATGCTTTCAAAAGAGCATTTAATCTCATTCATTACTCAGTCACCT CTTAAAGGCCACATCCTTTAATACTGTTGCTTTGGGGATTAAGTTTCGACATGAATTTTGGAGGGGACAAAAACATCCAAACCATAGCAA CATAAATGTATAGAATATTTCACACAAAGCAGAGTGCTGGGTAATGACCAGATATAAAGAAGTATTTGAAATGACCTTACCTCCAAGATG CTTATACTCTTAGAAAAGTTGACAGGTACAGATGGCTGTAATTTGAAGCAGCAGGTAGGATTCATTGCACCTATTATTCATTAAACACCT >63816_63816_17_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398227_DHRS7_chr14_60622870_ENST00000216500_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_18_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398227_DHRS7_chr14_60622870_ENST00000557185_length(transcript)=1245nt_BP=176nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATG GGAGCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTC TCTTGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACT TGTTTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGT CAACAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGAC GGTGTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATC TGTACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGG TATAATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAA TAATGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGAT CTCAGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAG GATTGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTT TTCAAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTT >63816_63816_18_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398227_DHRS7_chr14_60622870_ENST00000557185_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_19_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398229_DHRS7_chr14_60622870_ENST00000216500_length(transcript)=1987nt_BP=254nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGGAACACGACCATCTCCCTGCTGACCACCGACGACGCCATGGTCTCCATCGACCCCACCATGCCCGCGAATTCAGA ACGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATGGGAGCTGACTGA TATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTCTCTTGTGCTGTC AGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACTTGTTTTGCCCCT TGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGTCAACAATGGTGG AATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGACGGTGTCCTTGAC AAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATCTGTACCTCTTTC CATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGGTATAATAGTTTC TAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAATAATGGAGACCA GTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGATCTCAGAACAACC TTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAGGATTGAGAACTT TAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTTTTCAAGCCACTG GAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTTTTTAATAGATAT GACTTTGCTTCCAACATGGAATGAAATAAAAAATAAATAATAAAAGATTGCCATGAATCTTGCAAAAAAGGTATTAACTCATACTATATT CTTGGATAAAATAACCTTTTAAAATACTTTAGCACATATGCTTAAAATCTAAGTTAACAGATTTGTCTTAGTCCATTTGTGCTGCTATAA CAAAATACCACAGATTTGGTAATTTATAAACAACAGAAATCTGTTTTTCCTGGCTCTTGAGGCTGGGAATTCCAAGACCAATGCACCAGC AGAATTAGTGTCTGGTGAAGGCTGATCTCTGCTTCCAAGATGGCACCTCATTGCTGCATCCTCCACAGTGGAGGAATGTATGTCCTCACA TGGTGGAAGGGACAGAAGGGAAAGAGGAGCAAAATGCTTTCAAAAGAGCATTTAATCTCATTCATTACTCAGTCACCTCTTAAAGGCCAC ATCCTTTAATACTGTTGCTTTGGGGATTAAGTTTCGACATGAATTTTGGAGGGGACAAAAACATCCAAACCATAGCAACATAAATGTATA GAATATTTCACACAAAGCAGAGTGCTGGGTAATGACCAGATATAAAGAAGTATTTGAAATGACCTTACCTCCAAGATGCTTATACTCTTA GAAAAGTTGACAGGTACAGATGGCTGTAATTTGAAGCAGCAGGTAGGATTCATTGCACCTATTATTCATTAAACACCTGTTGTATGTCTT >63816_63816_19_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398229_DHRS7_chr14_60622870_ENST00000216500_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_20_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398229_DHRS7_chr14_60622870_ENST00000557185_length(transcript)=1323nt_BP=254nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGGAACACGACCATCTCCCTGCTGACCACCGACGACGCCATGGTCTCCATCGACCCCACCATGCCCGCGAATTCAGA ACGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATGGGAGCTGACTGA TATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTCTCTTGTGCTGTC AGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACTTGTTTTGCCCCT TGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGTCAACAATGGTGG AATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGACGGTGTCCTTGAC AAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATCTGTACCTCTTTC CATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGGTATAATAGTTTC TAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAATAATGGAGACCA GTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGATCTCAGAACAACC TTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAGGATTGAGAACTT TAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTTTTCAAGCCACTG GAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTTTTTAATAGATAT >63816_63816_20_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398229_DHRS7_chr14_60622870_ENST00000557185_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_21_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398232_DHRS7_chr14_60622870_ENST00000216500_length(transcript)=2188nt_BP=455nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGCACTCCGTACAAAGTGAGACCTGTGGCCATCAAGCAACTCTCCGCTGGTGTCGAGGACAAGAGAACCACAAGCCG TGGCCAGTCTGCTGAGAGACCACTGAGGGACAGACGGGTTGTGGGCCTGGAGCAGCCCCGGAGGGAAGGAGCATTTGAAAGTGGACAGGT AGAGCCCAGGCCCAGAGAGCCCCAGGGCTGCTACCAGGAAGGCCAGCGCATCCCTCCAGAGAGAGAAGAATTAATCCAGAGCGTGCTGGC GCAGGTTGCAGAGCAGTTCTCAAGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGT GGAATAATGGGAGCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACT AGGAGTTTCTCTTGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAA AGATATACTTGTTTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGA CATTCTGGTCAACAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTA CTTAGGGACGGTGTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGG TATCATATCTGTACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCAC ATACCCAGGTATAATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGAC TATAGGCAATAATGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGA AGTTTGGATCTCAGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGG GAAGAAAAGGATTGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCA CCTGTACTTTTCAAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTG ATTTTACTTTTTAATAGATATGACTTTGCTTCCAACATGGAATGAAATAAAAAATAAATAATAAAAGATTGCCATGAATCTTGCAAAAAA GGTATTAACTCATACTATATTCTTGGATAAAATAACCTTTTAAAATACTTTAGCACATATGCTTAAAATCTAAGTTAACAGATTTGTCTT AGTCCATTTGTGCTGCTATAACAAAATACCACAGATTTGGTAATTTATAAACAACAGAAATCTGTTTTTCCTGGCTCTTGAGGCTGGGAA TTCCAAGACCAATGCACCAGCAGAATTAGTGTCTGGTGAAGGCTGATCTCTGCTTCCAAGATGGCACCTCATTGCTGCATCCTCCACAGT GGAGGAATGTATGTCCTCACATGGTGGAAGGGACAGAAGGGAAAGAGGAGCAAAATGCTTTCAAAAGAGCATTTAATCTCATTCATTACT CAGTCACCTCTTAAAGGCCACATCCTTTAATACTGTTGCTTTGGGGATTAAGTTTCGACATGAATTTTGGAGGGGACAAAAACATCCAAA CCATAGCAACATAAATGTATAGAATATTTCACACAAAGCAGAGTGCTGGGTAATGACCAGATATAAAGAAGTATTTGAAATGACCTTACC TCCAAGATGCTTATACTCTTAGAAAAGTTGACAGGTACAGATGGCTGTAATTTGAAGCAGCAGGTAGGATTCATTGCACCTATTATTCAT >63816_63816_21_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398232_DHRS7_chr14_60622870_ENST00000216500_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_22_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398232_DHRS7_chr14_60622870_ENST00000557185_length(transcript)=1524nt_BP=455nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGCACTCCGTACAAAGTGAGACCTGTGGCCATCAAGCAACTCTCCGCTGGTGTCGAGGACAAGAGAACCACAAGCCG TGGCCAGTCTGCTGAGAGACCACTGAGGGACAGACGGGTTGTGGGCCTGGAGCAGCCCCGGAGGGAAGGAGCATTTGAAAGTGGACAGGT AGAGCCCAGGCCCAGAGAGCCCCAGGGCTGCTACCAGGAAGGCCAGCGCATCCCTCCAGAGAGAGAAGAATTAATCCAGAGCGTGCTGGC GCAGGTTGCAGAGCAGTTCTCAAGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGT GGAATAATGGGAGCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACT AGGAGTTTCTCTTGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAA AGATATACTTGTTTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGA CATTCTGGTCAACAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTA CTTAGGGACGGTGTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGG TATCATATCTGTACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCAC ATACCCAGGTATAATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGAC TATAGGCAATAATGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGA AGTTTGGATCTCAGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGG GAAGAAAAGGATTGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCA CCTGTACTTTTCAAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTG >63816_63816_22_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398232_DHRS7_chr14_60622870_ENST00000557185_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_23_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398234_DHRS7_chr14_60622870_ENST00000216500_length(transcript)=2086nt_BP=353nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGGAACACGACCATCTCCCTGCTGACCACCGACGACGCCATGGTCTCCATCGACCCCACCATGCCCGCGAATTCAGA ACGCACTCCGTACAAAGTGAGACCTGTGGCCATCAAGCAACTCTCCGAGAGAGAAGAATTAATCCAGAGCGTGCTGGCGCAGGTTGCAGA GCAGTTCTCAAGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATGGGA GCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTCTCT TGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACTTGT TTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGTCAA CAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGACGGT GTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATCTGT ACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGGTAT AATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAATAA TGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGATCTC AGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAGGAT TGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTTTTC AAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTTTTT AATAGATATGACTTTGCTTCCAACATGGAATGAAATAAAAAATAAATAATAAAAGATTGCCATGAATCTTGCAAAAAAGGTATTAACTCA TACTATATTCTTGGATAAAATAACCTTTTAAAATACTTTAGCACATATGCTTAAAATCTAAGTTAACAGATTTGTCTTAGTCCATTTGTG CTGCTATAACAAAATACCACAGATTTGGTAATTTATAAACAACAGAAATCTGTTTTTCCTGGCTCTTGAGGCTGGGAATTCCAAGACCAA TGCACCAGCAGAATTAGTGTCTGGTGAAGGCTGATCTCTGCTTCCAAGATGGCACCTCATTGCTGCATCCTCCACAGTGGAGGAATGTAT GTCCTCACATGGTGGAAGGGACAGAAGGGAAAGAGGAGCAAAATGCTTTCAAAAGAGCATTTAATCTCATTCATTACTCAGTCACCTCTT AAAGGCCACATCCTTTAATACTGTTGCTTTGGGGATTAAGTTTCGACATGAATTTTGGAGGGGACAAAAACATCCAAACCATAGCAACAT AAATGTATAGAATATTTCACACAAAGCAGAGTGCTGGGTAATGACCAGATATAAAGAAGTATTTGAAATGACCTTACCTCCAAGATGCTT ATACTCTTAGAAAAGTTGACAGGTACAGATGGCTGTAATTTGAAGCAGCAGGTAGGATTCATTGCACCTATTATTCATTAAACACCTGTT >63816_63816_23_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398234_DHRS7_chr14_60622870_ENST00000216500_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_24_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398234_DHRS7_chr14_60622870_ENST00000557185_length(transcript)=1422nt_BP=353nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGGAACACGACCATCTCCCTGCTGACCACCGACGACGCCATGGTCTCCATCGACCCCACCATGCCCGCGAATTCAGA ACGCACTCCGTACAAAGTGAGACCTGTGGCCATCAAGCAACTCTCCGAGAGAGAAGAATTAATCCAGAGCGTGCTGGCGCAGGTTGCAGA GCAGTTCTCAAGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATGGGA GCTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTCTCT TGTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACTTGT TTTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGTCAA CAATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGACGGT GTCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATCTGT ACCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGGTAT AATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAATAA TGGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGATCTC AGAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAGGAT TGAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTTTTC AAGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTTTTT >63816_63816_24_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398234_DHRS7_chr14_60622870_ENST00000557185_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_25_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398236_DHRS7_chr14_60622870_ENST00000216500_length(transcript)=2079nt_BP=346nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGGTAATCTTCAGCAAGTACTGCAACTCCAGCGACATCATGGACCTGTTCTGCATCGCCACCGGCCTGCCTCGCACT CCGTACAAAGTGAGACCTGTGGCCATCAAGCAACTCTCCGAGAGAGAAGAATTAATCCAGAGCGTGCTGGCGCAGGTTGCAGAGCAGTTC TCAAGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATGGGAGCTGACT GATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTCTCTTGTGCTG TCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACTTGTTTTGCCC CTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGTCAACAATGGT GGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGACGGTGTCCTTG ACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATCTGTACCTCTT TCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGGTATAATAGTT TCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAATAATGGAGAC CAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGATCTCAGAACAA CCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAGGATTGAGAAC TTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTTTTCAAGCCAC TGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTTTTTAATAGAT ATGACTTTGCTTCCAACATGGAATGAAATAAAAAATAAATAATAAAAGATTGCCATGAATCTTGCAAAAAAGGTATTAACTCATACTATA TTCTTGGATAAAATAACCTTTTAAAATACTTTAGCACATATGCTTAAAATCTAAGTTAACAGATTTGTCTTAGTCCATTTGTGCTGCTAT AACAAAATACCACAGATTTGGTAATTTATAAACAACAGAAATCTGTTTTTCCTGGCTCTTGAGGCTGGGAATTCCAAGACCAATGCACCA GCAGAATTAGTGTCTGGTGAAGGCTGATCTCTGCTTCCAAGATGGCACCTCATTGCTGCATCCTCCACAGTGGAGGAATGTATGTCCTCA CATGGTGGAAGGGACAGAAGGGAAAGAGGAGCAAAATGCTTTCAAAAGAGCATTTAATCTCATTCATTACTCAGTCACCTCTTAAAGGCC ACATCCTTTAATACTGTTGCTTTGGGGATTAAGTTTCGACATGAATTTTGGAGGGGACAAAAACATCCAAACCATAGCAACATAAATGTA TAGAATATTTCACACAAAGCAGAGTGCTGGGTAATGACCAGATATAAAGAAGTATTTGAAATGACCTTACCTCCAAGATGCTTATACTCT TAGAAAAGTTGACAGGTACAGATGGCTGTAATTTGAAGCAGCAGGTAGGATTCATTGCACCTATTATTCATTAAACACCTGTTGTATGTC >63816_63816_25_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398236_DHRS7_chr14_60622870_ENST00000216500_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_26_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398236_DHRS7_chr14_60622870_ENST00000557185_length(transcript)=1415nt_BP=346nt ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT GGACGCATTCAGAAGGTAATCTTCAGCAAGTACTGCAACTCCAGCGACATCATGGACCTGTTCTGCATCGCCACCGGCCTGCCTCGCACT CCGTACAAAGTGAGACCTGTGGCCATCAAGCAACTCTCCGAGAGAGAAGAATTAATCCAGAGCGTGCTGGCGCAGGTTGCAGAGCAGTTC TCAAGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATGGGAGCTGACT GATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTCTCTTGTGCTG TCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACTTGTTTTGCCC CTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGTCAACAATGGT GGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGACGGTGTCCTTG ACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATCTGTACCTCTT TCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGGTATAATAGTT TCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAATAATGGAGAC CAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGATCTCAGAACAA CCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAGGATTGAGAAC TTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTTTTCAAGCCAC TGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTTTTTAATAGAT >63816_63816_26_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000398236_DHRS7_chr14_60622870_ENST00000557185_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_27_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000539837_DHRS7_chr14_60622870_ENST00000216500_length(transcript)=2085nt_BP=352nt TCCCGCGGCGGCTGGCGTCGGGAAAGTACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGG CCCAAGGCCATCTACCTGGACATCGATGGACGCATTCAGAAGGTAATCTTCAGCAAGTACTGCAACTCCAGCGACATCATGGACCTGTTC TGCATCGCCACCGGCCTGCCTCGGAACACGACCATCTCCCTGCTGACCACCGACGACGCCATGGTCTCCATCGACCCCACCATGCCCGCG AATTCAGAACGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATGGGAG CTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTCTCTT GTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACTTGTT TTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGTCAAC AATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGACGGTG TCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATCTGTA CCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGGTATA ATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAATAAT GGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGATCTCA GAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAGGATT GAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTTTTCA AGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTTTTTA ATAGATATGACTTTGCTTCCAACATGGAATGAAATAAAAAATAAATAATAAAAGATTGCCATGAATCTTGCAAAAAAGGTATTAACTCAT ACTATATTCTTGGATAAAATAACCTTTTAAAATACTTTAGCACATATGCTTAAAATCTAAGTTAACAGATTTGTCTTAGTCCATTTGTGC TGCTATAACAAAATACCACAGATTTGGTAATTTATAAACAACAGAAATCTGTTTTTCCTGGCTCTTGAGGCTGGGAATTCCAAGACCAAT GCACCAGCAGAATTAGTGTCTGGTGAAGGCTGATCTCTGCTTCCAAGATGGCACCTCATTGCTGCATCCTCCACAGTGGAGGAATGTATG TCCTCACATGGTGGAAGGGACAGAAGGGAAAGAGGAGCAAAATGCTTTCAAAAGAGCATTTAATCTCATTCATTACTCAGTCACCTCTTA AAGGCCACATCCTTTAATACTGTTGCTTTGGGGATTAAGTTTCGACATGAATTTTGGAGGGGACAAAAACATCCAAACCATAGCAACATA AATGTATAGAATATTTCACACAAAGCAGAGTGCTGGGTAATGACCAGATATAAAGAAGTATTTGAAATGACCTTACCTCCAAGATGCTTA TACTCTTAGAAAAGTTGACAGGTACAGATGGCTGTAATTTGAAGCAGCAGGTAGGATTCATTGCACCTATTATTCATTAAACACCTGTTG >63816_63816_27_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000539837_DHRS7_chr14_60622870_ENST00000216500_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- >63816_63816_28_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000539837_DHRS7_chr14_60622870_ENST00000557185_length(transcript)=1421nt_BP=352nt TCCCGCGGCGGCTGGCGTCGGGAAAGTACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGG CCCAAGGCCATCTACCTGGACATCGATGGACGCATTCAGAAGGTAATCTTCAGCAAGTACTGCAACTCCAGCGACATCATGGACCTGTTC TGCATCGCCACCGGCCTGCCTCGGAACACGACCATCTCCCTGCTGACCACCGACGACGCCATGGTCTCCATCGACCCCACCATGCCCGCG AATTCAGAACGAGCATTCAAAATCAATGAACTGAAAGCTGAAGTTGCAAATCACTTGGCTGTCCTAGAGAAACGCGTGGAATAATGGGAG CTGACTGATATGGTGGTGTGGGTGACTGGAGCCTCGAGTGGAATTGGTGAGGAGCTGGCTTACCAGTTGTCTAAACTAGGAGTTTCTCTT GTGCTGTCAGCCAGAAGAGTGCATGAGCTGGAAAGGGTGAAAAGAAGATGCCTAGAGAATGGCAATTTAAAAGAAAAAGATATACTTGTT TTGCCCCTTGACCTGACCGACACTGGTTCCCATGAAGCGGCTACCAAAGCTGTTCTCCAGGAGTTTGGTAGAATCGACATTCTGGTCAAC AATGGTGGAATGTCCCAGCGTTCTCTGTGCATGGATACCAGCTTGGATGTCTACAGAAAGCTAATAGAGCTTAACTACTTAGGGACGGTG TCCTTGACAAAATGTGTTCTGCCTCACATGATCGAGAGGAAGCAAGGAAAGATTGTTACTGTGAATAGCATCCTGGGTATCATATCTGTA CCTCTTTCCATTGGATACTGTGCTAGCAAGCATGCTCTCCGGGGTTTTTTTAATGGCCTTCGAACAGAACTTGCCACATACCCAGGTATA ATAGTTTCTAACATTTGCCCAGGACCTGTGCAATCAAATATTGTGGAGAATTCCCTAGCTGGAGAAGTCACAAAGACTATAGGCAATAAT GGAGACCAGTCCCACAAGATGACAACCAGTCGTTGTGTGCGGCTGATGTTAATCAGCATGGCCAATGATTTGAAAGAAGTTTGGATCTCA GAACAACCTTTCTTGTTAGTAACATATTTGTGGCAATACATGCCAACCTGGGCCTGGTGGATAACCAACAAGATGGGGAAGAAAAGGATT GAGAACTTTAAGAGTGGTGTGGATGCAGACTCTTCTTATTTTAAAATCTTTAAGACAAAACATGACTGAAAAGAGCACCTGTACTTTTCA AGCCACTGGAGGGAGAAATGGAAAACATGAAAACAGCAATCTTCTTATGCTTCTGAATAATCAAAGACTAATTTGTGATTTTACTTTTTA >63816_63816_28_PDE9A-DHRS7_PDE9A_chr21_44153536_ENST00000539837_DHRS7_chr14_60622870_ENST00000557185_length(amino acids)=292AA_BP= MTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVN NGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI IVSNICPGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRI -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for PDE9A-DHRS7 |
Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
- Retained PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
- Lost PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
- Retained PPIs, but lost function due to frame-shift fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for PDE9A-DHRS7 |
Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for PDE9A-DHRS7 |
Diseases associated with fusion partners. (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | PDE9A | C0005586 | Bipolar Disorder | 1 | PSYGENET |
Tgene | C0015695 | Fatty Liver | 1 | CTD_human | |
Tgene | C0019193 | Hepatitis, Toxic | 1 | CTD_human | |
Tgene | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human | |
Tgene | C0860207 | Drug-Induced Liver Disease | 1 | CTD_human | |
Tgene | C1262760 | Hepatitis, Drug-Induced | 1 | CTD_human | |
Tgene | C2711227 | Steatohepatitis | 1 | CTD_human | |
Tgene | C3658290 | Drug-Induced Acute Liver Injury | 1 | CTD_human | |
Tgene | C4277682 | Chemical and Drug Induced Liver Injury | 1 | CTD_human | |
Tgene | C4279912 | Chemically-Induced Liver Toxicity | 1 | CTD_human |