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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:PIK3C2G-CTDSP2 (FusionGDB2 ID:HG5288TG10106) |
Fusion Gene Summary for PIK3C2G-CTDSP2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PIK3C2G-CTDSP2 | Fusion gene ID: hg5288tg10106 | Hgene | Tgene | Gene symbol | PIK3C2G | CTDSP2 | Gene ID | 5288 | 10106 |
| Gene name | phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma | CTD small phosphatase 2 | |
| Synonyms | PI3K-C2-gamma|PI3K-C2GAMMA | OS4|PSR2|SCP2 | |
| Cytomap | ('PIK3C2G')('CTDSP2') 12p12.3 | 12q14.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gammaPTDINS-3-kinase C2 gammaphosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptidephosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit g | carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2NLI-interacting factor 2conserved gene amplified in osteosarcomanuclear LIM interactor-intera | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000536967, ENST00000266497, ENST00000433979, ENST00000535651, ENST00000538779, | ||
| Fusion gene scores | * DoF score | 4 X 4 X 3=48 | 12 X 10 X 7=840 |
| # samples | 5 | 13 | |
| ** MAII score | log2(5/48*10)=0.0588936890535686 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(13/840*10)=-2.69187770463767 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PIK3C2G [Title/Abstract] AND CTDSP2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | PIK3C2G(18435693)-CTDSP2(58218102), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | PIK3C2G-CTDSP2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. PIK3C2G-CTDSP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | CTDSP2 | GO:0006470 | protein dephosphorylation | 12721286 |
| Fusion gene breakpoints across PIK3C2G (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across CTDSP2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | SARC | TCGA-DX-A1KZ-01A | PIK3C2G | chr12 | 18435693 | - | CTDSP2 | chr12 | 58218102 | - |
| ChimerDB4 | SARC | TCGA-DX-A1KZ-01A | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - |
| ChimerDB4 | SARC | TCGA-RN-AAAQ-01A | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - |
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Fusion Gene ORF analysis for PIK3C2G-CTDSP2 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000536967 | ENST00000398073 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - |
| 3UTR-5UTR | ENST00000536967 | ENST00000547701 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - |
| 3UTR-intron | ENST00000536967 | ENST00000548823 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - |
| 5CDS-5UTR | ENST00000266497 | ENST00000547701 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - |
| 5CDS-5UTR | ENST00000433979 | ENST00000547701 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - |
| 5CDS-5UTR | ENST00000535651 | ENST00000547701 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - |
| 5CDS-5UTR | ENST00000538779 | ENST00000547701 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - |
| 5CDS-intron | ENST00000266497 | ENST00000548823 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - |
| 5CDS-intron | ENST00000433979 | ENST00000548823 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - |
| 5CDS-intron | ENST00000535651 | ENST00000548823 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - |
| 5CDS-intron | ENST00000538779 | ENST00000548823 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - |
| In-frame | ENST00000266497 | ENST00000398073 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - |
| In-frame | ENST00000433979 | ENST00000398073 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - |
| In-frame | ENST00000535651 | ENST00000398073 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - |
| In-frame | ENST00000538779 | ENST00000398073 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000535651 | PIK3C2G | chr12 | 18435693 | + | ENST00000398073 | CTDSP2 | chr12 | 58218102 | - | 5305 | 1225 | 547 | 1629 | 360 |
| ENST00000433979 | PIK3C2G | chr12 | 18435693 | + | ENST00000398073 | CTDSP2 | chr12 | 58218102 | - | 4874 | 794 | 116 | 1198 | 360 |
| ENST00000538779 | PIK3C2G | chr12 | 18435693 | + | ENST00000398073 | CTDSP2 | chr12 | 58218102 | - | 4796 | 716 | 38 | 1120 | 360 |
| ENST00000266497 | PIK3C2G | chr12 | 18435693 | + | ENST00000398073 | CTDSP2 | chr12 | 58218102 | - | 4796 | 716 | 38 | 1120 | 360 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000535651 | ENST00000398073 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - | 0.000789355 | 0.9992106 |
| ENST00000433979 | ENST00000398073 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - | 0.000831929 | 0.99916804 |
| ENST00000538779 | ENST00000398073 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - | 0.000880276 | 0.9991197 |
| ENST00000266497 | ENST00000398073 | PIK3C2G | chr12 | 18435693 | + | CTDSP2 | chr12 | 58218102 | - | 0.000880276 | 0.9991197 |
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Fusion Genomic Features for PIK3C2G-CTDSP2 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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Fusion Protein Features for PIK3C2G-CTDSP2 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:18435693/chr12:58218102) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PIK3C2G | chr12:18435693 | chr12:58218102 | ENST00000266497 | + | 1 | 31 | 1199_1311 | 226 | 1446.0 | Domain | PX |
| Hgene | PIK3C2G | chr12:18435693 | chr12:58218102 | ENST00000266497 | + | 1 | 31 | 1328_1445 | 226 | 1446.0 | Domain | C2 |
| Hgene | PIK3C2G | chr12:18435693 | chr12:58218102 | ENST00000266497 | + | 1 | 31 | 285_371 | 226 | 1446.0 | Domain | PI3K-RBD |
| Hgene | PIK3C2G | chr12:18435693 | chr12:58218102 | ENST00000266497 | + | 1 | 31 | 453_628 | 226 | 1446.0 | Domain | C2 PI3K-type |
| Hgene | PIK3C2G | chr12:18435693 | chr12:58218102 | ENST00000266497 | + | 1 | 31 | 643_819 | 226 | 1446.0 | Domain | PIK helical |
| Hgene | PIK3C2G | chr12:18435693 | chr12:58218102 | ENST00000266497 | + | 1 | 31 | 916_1180 | 226 | 1446.0 | Domain | PI3K/PI4K |
| Hgene | PIK3C2G | chr12:18435693 | chr12:58218102 | ENST00000433979 | + | 2 | 32 | 1199_1311 | 226 | 1446.0 | Domain | PX |
| Hgene | PIK3C2G | chr12:18435693 | chr12:58218102 | ENST00000433979 | + | 2 | 32 | 1328_1445 | 226 | 1446.0 | Domain | C2 |
| Hgene | PIK3C2G | chr12:18435693 | chr12:58218102 | ENST00000433979 | + | 2 | 32 | 285_371 | 226 | 1446.0 | Domain | PI3K-RBD |
| Hgene | PIK3C2G | chr12:18435693 | chr12:58218102 | ENST00000433979 | + | 2 | 32 | 453_628 | 226 | 1446.0 | Domain | C2 PI3K-type |
| Hgene | PIK3C2G | chr12:18435693 | chr12:58218102 | ENST00000433979 | + | 2 | 32 | 643_819 | 226 | 1446.0 | Domain | PIK helical |
| Hgene | PIK3C2G | chr12:18435693 | chr12:58218102 | ENST00000433979 | + | 2 | 32 | 916_1180 | 226 | 1446.0 | Domain | PI3K/PI4K |
| Tgene | CTDSP2 | chr12:18435693 | chr12:58218102 | ENST00000398073 | 4 | 8 | 97_255 | 137 | 272.0 | Domain | FCP1 homology |
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Fusion Gene Sequence for PIK3C2G-CTDSP2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >65354_65354_1_PIK3C2G-CTDSP2_PIK3C2G_chr12_18435693_ENST00000266497_CTDSP2_chr12_58218102_ENST00000398073_length(transcript)=4796nt_BP=716nt GGAGCAGAGTCAACCCTCTCAGTTACATAAAATAAAAAATGGCATATTCTTGGCAAACGGATCCAAATCCTAATGAATCACACGAAAAGC AGTATGAACACCAAGAATTTCTCTTTGTAAATCAACCCCATTCTTCTAGCCAAGTCAGTCTGGGTTTTGATCAGATAGTAGATGAGATCA GTGGCAAAATTCCACACTACGAGAGTGAAATTGATGAAAACACCTTTTTTGTGCCCACTGCACCAAAATGGGACTCAACAGGGCATTCAT TAAATGAAGCACACCAAATATCCTTGAATGAATTCACTTCTAAAAGCCGTGAACTCTCCTGGCATCAAGTTAGCAAAGCACCAGCAATTG GTTTTAGTCCTTCTGTGTTACCAAAACCTCAAAATACGAATAAAGAATGCTCCTGGGGAAGCCCCATAGGAAAACATCATGGTGCTGATG ATTCCAGATTCAGTATTTTAGCTCCATCATTCACAAGTTTGGATAAAATTAATCTAGAGAAAGAATTAGAAAATGAAAATCATAACTACC ATATAGGATTTGAAAGTAGCATTCCTCCAACAAATTCATCCTTCTCAAGTGACTTCATGCCGAAAGAAGAGAATAAAAGGAGTGGACATG TGAACATTGTGGAACCATCTTTGATGCTTTTGAAAGGCTCTCTTCAACCCGGAATGTGGGAAAGTACATGGCAGAAGAATATAGAGGTGT ATGTGCTCAAGAGGCCTTATGTGGATGAGTTCCTGAGACGCATGGGGGAACTCTTTGAATGTGTTCTCTTCACTGCCAGCCTGGCCAAGT ATGCCGACCCTGTGACAGACCTGCTGGACCGGTGTGGGGTGTTCCGGGCCCGCCTATTCCGTGAGTCTTGCGTGTTCCACCAGGGCTGCT ACGTCAAGGACCTCAGCCGCCTGGGGAGGGACCTGAGAAAGACCCTCATCCTGGACAACTCGCCTGCTTCTTACATATTCCACCCCGAGA ATGCAGTGCCTGTGCAGTCCTGGTTTGATGACATGGCAGACACTGAGTTGCTGAACCTGATCCCAATCTTTGAGGAGCTGAGCGGAGCAG AGGACGTCTACACCAGCCTTGGGCAGCTGCGGGCCCCTTAGCCTGCCCTGCTTCCAAGCGACGGCCATCCCAGTAGGGGACTTTCCCACA CTGTGCCTTTACGATCAGCGTGACAGAGTAGAAGCTGGAGTGCCTCACCACACGGCCCGGAAACAGCGGGAAGTAACTGGAAAGAGCTTT AGGACAGCTTAGATGCCGAGTGGGCGAATGCCAGACCAATGATACCCAGAGCTACCTGCCGCCAACTTGTTGAGATGTGTGTTTGACTGT GAGAGAGTGTGTGTTTGTGTGTGTGTTTTGCCATGAACTGTGGCCCCAGTGTATAGTGTTTCAGTGGGGGAGAAGCTGAAAGACCAAGAC TCTTCCCAAGTTAGCTTGTCTCCTCTCCTGTCACCCTAAGAGCCACTGAGTTGTGTAGGGATGAAGACTATTGAAGACTCCATTGCCAAA CCATGGCCTTTCCTCAGTGTTGTAAGGCCTATGCCAAGGATAAAGGAAGGGTATGCCTTTGGGTACTCCAGGCACACACCTTTCTGAAAT CCTTCTCCAGCCAGCTGCTGCAGACAAAAGATCACATTTCTGGGAAGATGAGAACTTGTTTCCAGACCAGCATCCAGTGGCCATCAGGTC TTGTGGCCCAAAGGCTATGCTTGCCTCCGGCTGAGTGCCTGGGATAGGCCTTTTCTATGTCTCCCCAAGGCTGGGGTGCTGAGCCTGCCT TCCTCACCACCTAGCCATAGTCTCAAACCTGTGGGGAAGGAGGTTTTCTCCCTGCCCGGGAAGAGGACAGATAACTGATTTCCGTTCTTT TGACTGTGTTTTAAAATTCTCTTTCTAAACACAGAGTGTTGGGCCTGGTTTGTTTCTGACAAAGTTACAGTCCTGGGCCTGTAATGAATG TCGGCGGCGCTGGGGTTGCAGGGAAAAGACAAATCCTCAAAGCGTGGACGTGTGTCCCCATGGCTTGTGGATCAGCTAAGCTCGGGATCA TTTCCATAAGTCTGCTTTTCAGGGATTCTCTGCTGGTGCTGGTGCAAGGACTTCTGTTCCAAAGGCTGGGAAAAACTAAGCTGTCCCAGC CCCTCCCATTTCTTGGGCAGGGCTCTTTTCCTGTTGTGTCTTCCCCCAGGGCCTGTCCTGTACCGAGCTCTGTCTGTTCCAGCCTTCATC CTTCCTGGCTGTTGCTTTTCCTCTTAAGGGCCTCAGAACTCTTGCTCTTCCTGGGCTGAGGGGGAATGAGTGTTCTTGCCATTTGCCAGC CTAATGCGCATGCTTTCTGCCTCTGGTAACAGGAGTGAGTGAGCCCCTCAGACCTGCACTCTGGGTGTCTCCTGCTTTCAAAGGTTCTTA ATAGTGAATGCTTTAAAATTAAAGTCATCACGAAATGGAAGTTTTCCCAGGGTGGAAAATAAGAGGAAGTGCTGCTGTAATTGGGAGCAC AAGGGGCCTCCCAAAAAGGAGCCCCACCTCAGCATCACTGCCTTAATCGTGGCCTCCCTGGGGTGGGTGGGGTTCTCTCCTCCCTCCCTC CCTCCTCCTGGGGTGGGAGGGCGCTCCTGTTCCCATCTCTGTGTTCCCTGGAGGCAGGTATCACAAAGCATTTGTGAATTGCTTTAGGTG CAGGGACACCACCCACTCAGGACTCTTCCCCATCATCCCTTCCATTGCCACACCCTAGATCCAGCCTCAGGAACTAACAAGTTTTGAGAA AAGCAGGTAGTAGAGCAGCAGCTTCGTGCTCTCAGCGGTGGCTGGCTGGCATTTTTCTCTAGCGTTGTGGTGCCACCTTCCCTTCTTGTC CCAAGGTTATAAGGCCTTGTCTTTCTCTTTGGAATCATAAAGTGGAACAGAGTCCCCAGAACTCATGTGGCCATTTCCGCCAGCATCACT CCCCGGTGCCTATGGGGTCCCGGTGTACCTAAAGGGAGAAGGACCCCATGTGCTAGCCAGAAATATACTGTCTCTTGAAGGAAAGCAGGA GCTCAGACTCTTAGAGCCAGCTGTGGCTTCGGACCCAAGGCCTGACCTAGGCTGCTATCCTAATATTGCAGGAGGGGCCTCTCTTCCAAG CCCCACCCTAAGGGTTAGCCCTTGGCCAAATCTTTTGCCGTCTAGGCCCAGCCAGGCTTTTCTGACTAAATAAGCAATAAGAGGCTCTAA GCTGACTGAGTTGCAAGGACCCTTTCCGCCCTCCCTTGGATCTCCATGTTTTTCCAGATGGCGGAAGAGCATGTGCCACCCCCTTTCCTA ACAGACTTGTCCAAGTGCTTGGCGTGGGACCCATGACCAAAGCCCAGGATGGCTTGGTGGGAGTGTCCCTGCTGCATCTGCATGAAGCCC CTGCTTTTTAGGCCTCACTCCCATCAGAACCCTGCCTGCCCACCTGCAACTCCCCCCCAACAATGCCATTCCCACTTGCCCCAGAGAAGC TACTCGGCCAAACCTAGCCAGGGTCTGTTCTTGTGGACCAGAGCCAGCCTAGTCATTATTTGCTGTCGGGTTTCCAGTTTCACCGTGTGT TAGGGTGAGGGATGATTGTAAAATTTGCTCCTCAAAGGAATCAGGCCAGACTCAATTTTGGAGGGCAAGACAGGGAGGAGGCCGCTTCAT CCCAGACTCTCTTCTAGGGCTTCCCACCATCAGCCCCTCCCACTTGAGACTGGTCTTTGGGAGGCAATAGGCCACCATGCCTGGTCAGCA CCAATTCAAGCCATGCCAGGAATCTGCCTACCTGCCAGGTTCAGTTCTTTTAAGGTGCCTCTTCAGGGACACAGTGTGTCTCTCTGATTG GGCTTCTAAATCAAAAGCCTGATGTTCGTGTCCCTCTCATAGGGGGAGCTTTGGACACAGGACCAGTTTGGAAAAGGGTCAGGTAAGGGT TTCCACTCTGCACATTGTAGAGGGAACACTCTGTAGGCCCATGGGTCCCTTACTAGAGAGGTTGAGTGAATTTGCCTTCAGTTAACATGG GACCTTCTGTTTAGCTTCCTCTTGCTTCCCAAAGATTTTAAGCATTTTGTAAATGTATAAACTCACCTCTGGTAACAGTGGCCCAGACGC TGCTTTGTGCTAAAAGCATGGGAAATGTAAAGGCAGTCTTTCTCTGGGAAATGGATGCTATTCTATTCTGCTGCCCCTACCTGTTCCTGA GGCCTCATTTAGAAAGAAAATCCCCTCAGAAGGCTGTCTGGCACCCAGTGTCCTAGCCAGGCCAAGTATATGAGAAAGGTAAGTCCATTT TCCCCTTCAGGTCCTCAGTGGATTACTTAACCACTGCTGTCCCTCGGTCCCTTTTTCCTAAACGGGTTTAGTTCTGTCTTTTTTCTCCTT TTTTCTAAATGCTGGTAAATATTTACATTCAGCCAGGGAAGAGGAGGCCAGAGGTCGGGCCAGCTGCCCCATTCTTTTAACGTTGTAGGG CCTGCCCATGGAGCGGACCCTCCTCTTTGGGCCTCGTGAGCTTTTTTGCTTATCATGTTCCATTTCGTGCCGCTTTCCCCCTTCAAGATG CCATTTGGAGGGTAGGGGATCTGCTTCCCACTGTGACTGGGCTATGGGATTCTGACTACCTTGCTTACAGATTCATGGTTTGATAAATTT GTTGTATTCAAAAACTTGAAATGCAGGACGCCATTAAGTGTCTGTTTATATTTTTGGAATATTTGTATTACTTACAATTAATTAATAAAA GTGGGTTTAAAAAACCTTTCCAGGAA >65354_65354_1_PIK3C2G-CTDSP2_PIK3C2G_chr12_18435693_ENST00000266497_CTDSP2_chr12_58218102_ENST00000398073_length(amino acids)=360AA_BP=226 MAYSWQTDPNPNESHEKQYEHQEFLFVNQPHSSSQVSLGFDQIVDEISGKIPHYESEIDENTFFVPTAPKWDSTGHSLNEAHQISLNEFT SKSRELSWHQVSKAPAIGFSPSVLPKPQNTNKECSWGSPIGKHHGADDSRFSILAPSFTSLDKINLEKELENENHNYHIGFESSIPPTNS SFSSDFMPKEENKRSGHVNIVEPSLMLLKGSLQPGMWESTWQKNIEVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCG VFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPIFEELSGAEDVYTSLGQLRAP -------------------------------------------------------------- >65354_65354_2_PIK3C2G-CTDSP2_PIK3C2G_chr12_18435693_ENST00000433979_CTDSP2_chr12_58218102_ENST00000398073_length(transcript)=4874nt_BP=794nt TGAGATCGTGTTTCATTTCAGGAAGATATATGCGTCAGGAAAATTTCTATCTTCTTTTGTATTATCAAGGAGATATTTGGAGCAGAGTCA ACCCTCTCAGTTACATAAAATAAAAAATGGCATATTCTTGGCAAACGGATCCAAATCCTAATGAATCACACGAAAAGCAGTATGAACACC AAGAATTTCTCTTTGTAAATCAACCCCATTCTTCTAGCCAAGTCAGTCTGGGTTTTGATCAGATAGTAGATGAGATCAGTGGCAAAATTC CACACTACGAGAGTGAAATTGATGAAAACACCTTTTTTGTGCCCACTGCACCAAAATGGGACTCAACAGGGCATTCATTAAATGAAGCAC ACCAAATATCCTTGAATGAATTCACTTCTAAAAGCCGTGAACTCTCCTGGCATCAAGTTAGCAAAGCACCAGCAATTGGTTTTAGTCCTT CTGTGTTACCAAAACCTCAAAATACGAATAAAGAATGCTCCTGGGGAAGCCCCATAGGAAAACATCATGGTGCTGATGATTCCAGATTCA GTATTTTAGCTCCATCATTCACAAGTTTGGATAAAATTAATCTAGAGAAAGAATTAGAAAATGAAAATCATAACTACCATATAGGATTTG AAAGTAGCATTCCTCCAACAAATTCATCCTTCTCAAGTGACTTCATGCCGAAAGAAGAGAATAAAAGGAGTGGACATGTGAACATTGTGG AACCATCTTTGATGCTTTTGAAAGGCTCTCTTCAACCCGGAATGTGGGAAAGTACATGGCAGAAGAATATAGAGGTGTATGTGCTCAAGA GGCCTTATGTGGATGAGTTCCTGAGACGCATGGGGGAACTCTTTGAATGTGTTCTCTTCACTGCCAGCCTGGCCAAGTATGCCGACCCTG TGACAGACCTGCTGGACCGGTGTGGGGTGTTCCGGGCCCGCCTATTCCGTGAGTCTTGCGTGTTCCACCAGGGCTGCTACGTCAAGGACC TCAGCCGCCTGGGGAGGGACCTGAGAAAGACCCTCATCCTGGACAACTCGCCTGCTTCTTACATATTCCACCCCGAGAATGCAGTGCCTG TGCAGTCCTGGTTTGATGACATGGCAGACACTGAGTTGCTGAACCTGATCCCAATCTTTGAGGAGCTGAGCGGAGCAGAGGACGTCTACA CCAGCCTTGGGCAGCTGCGGGCCCCTTAGCCTGCCCTGCTTCCAAGCGACGGCCATCCCAGTAGGGGACTTTCCCACACTGTGCCTTTAC GATCAGCGTGACAGAGTAGAAGCTGGAGTGCCTCACCACACGGCCCGGAAACAGCGGGAAGTAACTGGAAAGAGCTTTAGGACAGCTTAG ATGCCGAGTGGGCGAATGCCAGACCAATGATACCCAGAGCTACCTGCCGCCAACTTGTTGAGATGTGTGTTTGACTGTGAGAGAGTGTGT GTTTGTGTGTGTGTTTTGCCATGAACTGTGGCCCCAGTGTATAGTGTTTCAGTGGGGGAGAAGCTGAAAGACCAAGACTCTTCCCAAGTT AGCTTGTCTCCTCTCCTGTCACCCTAAGAGCCACTGAGTTGTGTAGGGATGAAGACTATTGAAGACTCCATTGCCAAACCATGGCCTTTC CTCAGTGTTGTAAGGCCTATGCCAAGGATAAAGGAAGGGTATGCCTTTGGGTACTCCAGGCACACACCTTTCTGAAATCCTTCTCCAGCC AGCTGCTGCAGACAAAAGATCACATTTCTGGGAAGATGAGAACTTGTTTCCAGACCAGCATCCAGTGGCCATCAGGTCTTGTGGCCCAAA GGCTATGCTTGCCTCCGGCTGAGTGCCTGGGATAGGCCTTTTCTATGTCTCCCCAAGGCTGGGGTGCTGAGCCTGCCTTCCTCACCACCT AGCCATAGTCTCAAACCTGTGGGGAAGGAGGTTTTCTCCCTGCCCGGGAAGAGGACAGATAACTGATTTCCGTTCTTTTGACTGTGTTTT AAAATTCTCTTTCTAAACACAGAGTGTTGGGCCTGGTTTGTTTCTGACAAAGTTACAGTCCTGGGCCTGTAATGAATGTCGGCGGCGCTG GGGTTGCAGGGAAAAGACAAATCCTCAAAGCGTGGACGTGTGTCCCCATGGCTTGTGGATCAGCTAAGCTCGGGATCATTTCCATAAGTC TGCTTTTCAGGGATTCTCTGCTGGTGCTGGTGCAAGGACTTCTGTTCCAAAGGCTGGGAAAAACTAAGCTGTCCCAGCCCCTCCCATTTC TTGGGCAGGGCTCTTTTCCTGTTGTGTCTTCCCCCAGGGCCTGTCCTGTACCGAGCTCTGTCTGTTCCAGCCTTCATCCTTCCTGGCTGT TGCTTTTCCTCTTAAGGGCCTCAGAACTCTTGCTCTTCCTGGGCTGAGGGGGAATGAGTGTTCTTGCCATTTGCCAGCCTAATGCGCATG CTTTCTGCCTCTGGTAACAGGAGTGAGTGAGCCCCTCAGACCTGCACTCTGGGTGTCTCCTGCTTTCAAAGGTTCTTAATAGTGAATGCT TTAAAATTAAAGTCATCACGAAATGGAAGTTTTCCCAGGGTGGAAAATAAGAGGAAGTGCTGCTGTAATTGGGAGCACAAGGGGCCTCCC AAAAAGGAGCCCCACCTCAGCATCACTGCCTTAATCGTGGCCTCCCTGGGGTGGGTGGGGTTCTCTCCTCCCTCCCTCCCTCCTCCTGGG GTGGGAGGGCGCTCCTGTTCCCATCTCTGTGTTCCCTGGAGGCAGGTATCACAAAGCATTTGTGAATTGCTTTAGGTGCAGGGACACCAC CCACTCAGGACTCTTCCCCATCATCCCTTCCATTGCCACACCCTAGATCCAGCCTCAGGAACTAACAAGTTTTGAGAAAAGCAGGTAGTA GAGCAGCAGCTTCGTGCTCTCAGCGGTGGCTGGCTGGCATTTTTCTCTAGCGTTGTGGTGCCACCTTCCCTTCTTGTCCCAAGGTTATAA GGCCTTGTCTTTCTCTTTGGAATCATAAAGTGGAACAGAGTCCCCAGAACTCATGTGGCCATTTCCGCCAGCATCACTCCCCGGTGCCTA TGGGGTCCCGGTGTACCTAAAGGGAGAAGGACCCCATGTGCTAGCCAGAAATATACTGTCTCTTGAAGGAAAGCAGGAGCTCAGACTCTT AGAGCCAGCTGTGGCTTCGGACCCAAGGCCTGACCTAGGCTGCTATCCTAATATTGCAGGAGGGGCCTCTCTTCCAAGCCCCACCCTAAG GGTTAGCCCTTGGCCAAATCTTTTGCCGTCTAGGCCCAGCCAGGCTTTTCTGACTAAATAAGCAATAAGAGGCTCTAAGCTGACTGAGTT GCAAGGACCCTTTCCGCCCTCCCTTGGATCTCCATGTTTTTCCAGATGGCGGAAGAGCATGTGCCACCCCCTTTCCTAACAGACTTGTCC AAGTGCTTGGCGTGGGACCCATGACCAAAGCCCAGGATGGCTTGGTGGGAGTGTCCCTGCTGCATCTGCATGAAGCCCCTGCTTTTTAGG CCTCACTCCCATCAGAACCCTGCCTGCCCACCTGCAACTCCCCCCCAACAATGCCATTCCCACTTGCCCCAGAGAAGCTACTCGGCCAAA CCTAGCCAGGGTCTGTTCTTGTGGACCAGAGCCAGCCTAGTCATTATTTGCTGTCGGGTTTCCAGTTTCACCGTGTGTTAGGGTGAGGGA TGATTGTAAAATTTGCTCCTCAAAGGAATCAGGCCAGACTCAATTTTGGAGGGCAAGACAGGGAGGAGGCCGCTTCATCCCAGACTCTCT TCTAGGGCTTCCCACCATCAGCCCCTCCCACTTGAGACTGGTCTTTGGGAGGCAATAGGCCACCATGCCTGGTCAGCACCAATTCAAGCC ATGCCAGGAATCTGCCTACCTGCCAGGTTCAGTTCTTTTAAGGTGCCTCTTCAGGGACACAGTGTGTCTCTCTGATTGGGCTTCTAAATC AAAAGCCTGATGTTCGTGTCCCTCTCATAGGGGGAGCTTTGGACACAGGACCAGTTTGGAAAAGGGTCAGGTAAGGGTTTCCACTCTGCA CATTGTAGAGGGAACACTCTGTAGGCCCATGGGTCCCTTACTAGAGAGGTTGAGTGAATTTGCCTTCAGTTAACATGGGACCTTCTGTTT AGCTTCCTCTTGCTTCCCAAAGATTTTAAGCATTTTGTAAATGTATAAACTCACCTCTGGTAACAGTGGCCCAGACGCTGCTTTGTGCTA AAAGCATGGGAAATGTAAAGGCAGTCTTTCTCTGGGAAATGGATGCTATTCTATTCTGCTGCCCCTACCTGTTCCTGAGGCCTCATTTAG AAAGAAAATCCCCTCAGAAGGCTGTCTGGCACCCAGTGTCCTAGCCAGGCCAAGTATATGAGAAAGGTAAGTCCATTTTCCCCTTCAGGT CCTCAGTGGATTACTTAACCACTGCTGTCCCTCGGTCCCTTTTTCCTAAACGGGTTTAGTTCTGTCTTTTTTCTCCTTTTTTCTAAATGC TGGTAAATATTTACATTCAGCCAGGGAAGAGGAGGCCAGAGGTCGGGCCAGCTGCCCCATTCTTTTAACGTTGTAGGGCCTGCCCATGGA GCGGACCCTCCTCTTTGGGCCTCGTGAGCTTTTTTGCTTATCATGTTCCATTTCGTGCCGCTTTCCCCCTTCAAGATGCCATTTGGAGGG TAGGGGATCTGCTTCCCACTGTGACTGGGCTATGGGATTCTGACTACCTTGCTTACAGATTCATGGTTTGATAAATTTGTTGTATTCAAA AACTTGAAATGCAGGACGCCATTAAGTGTCTGTTTATATTTTTGGAATATTTGTATTACTTACAATTAATTAATAAAAGTGGGTTTAAAA AACCTTTCCAGGAA >65354_65354_2_PIK3C2G-CTDSP2_PIK3C2G_chr12_18435693_ENST00000433979_CTDSP2_chr12_58218102_ENST00000398073_length(amino acids)=360AA_BP=226 MAYSWQTDPNPNESHEKQYEHQEFLFVNQPHSSSQVSLGFDQIVDEISGKIPHYESEIDENTFFVPTAPKWDSTGHSLNEAHQISLNEFT SKSRELSWHQVSKAPAIGFSPSVLPKPQNTNKECSWGSPIGKHHGADDSRFSILAPSFTSLDKINLEKELENENHNYHIGFESSIPPTNS SFSSDFMPKEENKRSGHVNIVEPSLMLLKGSLQPGMWESTWQKNIEVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCG VFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPIFEELSGAEDVYTSLGQLRAP -------------------------------------------------------------- >65354_65354_3_PIK3C2G-CTDSP2_PIK3C2G_chr12_18435693_ENST00000535651_CTDSP2_chr12_58218102_ENST00000398073_length(transcript)=5305nt_BP=1225nt ATAGGGCAGGCAAGGGGAAGGCTGGTCACTCCACCCTAATCTTACAATGCAAATGGACTTTCCAGTTGATCAGCACCATCTTGTCTGCTT CTTATTGTACATATGCCTGACAAAAGGAAGGGAAGATGGAGCCGCCATCTTGAACATGTCTAGTCCTTAGTTCCTGCCACATTCACACGT GCAAGCTCCCAGCTTGCTTCTCTGTGTCTGCCCCTCAACTTTACAGGCTGCTCTTTGTTAGAAAATGATTTGGGACTGCTTTTCATTAAA AAGGAAAGCCTTACCGAGGACTCCCATACCCTTACTATCTGCCTAAGTAATTTATTCTTAACTCCTGTACCAGTGAGAATCAAATTATTG AGAATTGTTGAGAAGCAGAAACTAACTACCTGGATTGTAAACCAAGGAAATGGTACCTGAAAACTGCCAACGGTACCTGAGAATGGAGCT GACACAGAGAAAAGCACAGGAAAATTTCTATCTTCTTTTGTATTATCAAGGAGATATTTGGAGCAGAGTCAACCCTCTCAGTTACATAAA ATAAAAAATGGCATATTCTTGGCAAACGGATCCAAATCCTAATGAATCACACGAAAAGCAGTATGAACACCAAGAATTTCTCTTTGTAAA TCAACCCCATTCTTCTAGCCAAGTCAGTCTGGGTTTTGATCAGATAGTAGATGAGATCAGTGGCAAAATTCCACACTACGAGAGTGAAAT TGATGAAAACACCTTTTTTGTGCCCACTGCACCAAAATGGGACTCAACAGGGCATTCATTAAATGAAGCACACCAAATATCCTTGAATGA ATTCACTTCTAAAAGCCGTGAACTCTCCTGGCATCAAGTTAGCAAAGCACCAGCAATTGGTTTTAGTCCTTCTGTGTTACCAAAACCTCA AAATACGAATAAAGAATGCTCCTGGGGAAGCCCCATAGGAAAACATCATGGTGCTGATGATTCCAGATTCAGTATTTTAGCTCCATCATT CACAAGTTTGGATAAAATTAATCTAGAGAAAGAATTAGAAAATGAAAATCATAACTACCATATAGGATTTGAAAGTAGCATTCCTCCAAC AAATTCATCCTTCTCAAGTGACTTCATGCCGAAAGAAGAGAATAAAAGGAGTGGACATGTGAACATTGTGGAACCATCTTTGATGCTTTT GAAAGGCTCTCTTCAACCCGGAATGTGGGAAAGTACATGGCAGAAGAATATAGAGGTGTATGTGCTCAAGAGGCCTTATGTGGATGAGTT CCTGAGACGCATGGGGGAACTCTTTGAATGTGTTCTCTTCACTGCCAGCCTGGCCAAGTATGCCGACCCTGTGACAGACCTGCTGGACCG GTGTGGGGTGTTCCGGGCCCGCCTATTCCGTGAGTCTTGCGTGTTCCACCAGGGCTGCTACGTCAAGGACCTCAGCCGCCTGGGGAGGGA CCTGAGAAAGACCCTCATCCTGGACAACTCGCCTGCTTCTTACATATTCCACCCCGAGAATGCAGTGCCTGTGCAGTCCTGGTTTGATGA CATGGCAGACACTGAGTTGCTGAACCTGATCCCAATCTTTGAGGAGCTGAGCGGAGCAGAGGACGTCTACACCAGCCTTGGGCAGCTGCG GGCCCCTTAGCCTGCCCTGCTTCCAAGCGACGGCCATCCCAGTAGGGGACTTTCCCACACTGTGCCTTTACGATCAGCGTGACAGAGTAG AAGCTGGAGTGCCTCACCACACGGCCCGGAAACAGCGGGAAGTAACTGGAAAGAGCTTTAGGACAGCTTAGATGCCGAGTGGGCGAATGC CAGACCAATGATACCCAGAGCTACCTGCCGCCAACTTGTTGAGATGTGTGTTTGACTGTGAGAGAGTGTGTGTTTGTGTGTGTGTTTTGC CATGAACTGTGGCCCCAGTGTATAGTGTTTCAGTGGGGGAGAAGCTGAAAGACCAAGACTCTTCCCAAGTTAGCTTGTCTCCTCTCCTGT CACCCTAAGAGCCACTGAGTTGTGTAGGGATGAAGACTATTGAAGACTCCATTGCCAAACCATGGCCTTTCCTCAGTGTTGTAAGGCCTA TGCCAAGGATAAAGGAAGGGTATGCCTTTGGGTACTCCAGGCACACACCTTTCTGAAATCCTTCTCCAGCCAGCTGCTGCAGACAAAAGA TCACATTTCTGGGAAGATGAGAACTTGTTTCCAGACCAGCATCCAGTGGCCATCAGGTCTTGTGGCCCAAAGGCTATGCTTGCCTCCGGC TGAGTGCCTGGGATAGGCCTTTTCTATGTCTCCCCAAGGCTGGGGTGCTGAGCCTGCCTTCCTCACCACCTAGCCATAGTCTCAAACCTG TGGGGAAGGAGGTTTTCTCCCTGCCCGGGAAGAGGACAGATAACTGATTTCCGTTCTTTTGACTGTGTTTTAAAATTCTCTTTCTAAACA CAGAGTGTTGGGCCTGGTTTGTTTCTGACAAAGTTACAGTCCTGGGCCTGTAATGAATGTCGGCGGCGCTGGGGTTGCAGGGAAAAGACA AATCCTCAAAGCGTGGACGTGTGTCCCCATGGCTTGTGGATCAGCTAAGCTCGGGATCATTTCCATAAGTCTGCTTTTCAGGGATTCTCT GCTGGTGCTGGTGCAAGGACTTCTGTTCCAAAGGCTGGGAAAAACTAAGCTGTCCCAGCCCCTCCCATTTCTTGGGCAGGGCTCTTTTCC TGTTGTGTCTTCCCCCAGGGCCTGTCCTGTACCGAGCTCTGTCTGTTCCAGCCTTCATCCTTCCTGGCTGTTGCTTTTCCTCTTAAGGGC CTCAGAACTCTTGCTCTTCCTGGGCTGAGGGGGAATGAGTGTTCTTGCCATTTGCCAGCCTAATGCGCATGCTTTCTGCCTCTGGTAACA GGAGTGAGTGAGCCCCTCAGACCTGCACTCTGGGTGTCTCCTGCTTTCAAAGGTTCTTAATAGTGAATGCTTTAAAATTAAAGTCATCAC GAAATGGAAGTTTTCCCAGGGTGGAAAATAAGAGGAAGTGCTGCTGTAATTGGGAGCACAAGGGGCCTCCCAAAAAGGAGCCCCACCTCA GCATCACTGCCTTAATCGTGGCCTCCCTGGGGTGGGTGGGGTTCTCTCCTCCCTCCCTCCCTCCTCCTGGGGTGGGAGGGCGCTCCTGTT CCCATCTCTGTGTTCCCTGGAGGCAGGTATCACAAAGCATTTGTGAATTGCTTTAGGTGCAGGGACACCACCCACTCAGGACTCTTCCCC ATCATCCCTTCCATTGCCACACCCTAGATCCAGCCTCAGGAACTAACAAGTTTTGAGAAAAGCAGGTAGTAGAGCAGCAGCTTCGTGCTC TCAGCGGTGGCTGGCTGGCATTTTTCTCTAGCGTTGTGGTGCCACCTTCCCTTCTTGTCCCAAGGTTATAAGGCCTTGTCTTTCTCTTTG GAATCATAAAGTGGAACAGAGTCCCCAGAACTCATGTGGCCATTTCCGCCAGCATCACTCCCCGGTGCCTATGGGGTCCCGGTGTACCTA AAGGGAGAAGGACCCCATGTGCTAGCCAGAAATATACTGTCTCTTGAAGGAAAGCAGGAGCTCAGACTCTTAGAGCCAGCTGTGGCTTCG GACCCAAGGCCTGACCTAGGCTGCTATCCTAATATTGCAGGAGGGGCCTCTCTTCCAAGCCCCACCCTAAGGGTTAGCCCTTGGCCAAAT CTTTTGCCGTCTAGGCCCAGCCAGGCTTTTCTGACTAAATAAGCAATAAGAGGCTCTAAGCTGACTGAGTTGCAAGGACCCTTTCCGCCC TCCCTTGGATCTCCATGTTTTTCCAGATGGCGGAAGAGCATGTGCCACCCCCTTTCCTAACAGACTTGTCCAAGTGCTTGGCGTGGGACC CATGACCAAAGCCCAGGATGGCTTGGTGGGAGTGTCCCTGCTGCATCTGCATGAAGCCCCTGCTTTTTAGGCCTCACTCCCATCAGAACC CTGCCTGCCCACCTGCAACTCCCCCCCAACAATGCCATTCCCACTTGCCCCAGAGAAGCTACTCGGCCAAACCTAGCCAGGGTCTGTTCT TGTGGACCAGAGCCAGCCTAGTCATTATTTGCTGTCGGGTTTCCAGTTTCACCGTGTGTTAGGGTGAGGGATGATTGTAAAATTTGCTCC TCAAAGGAATCAGGCCAGACTCAATTTTGGAGGGCAAGACAGGGAGGAGGCCGCTTCATCCCAGACTCTCTTCTAGGGCTTCCCACCATC AGCCCCTCCCACTTGAGACTGGTCTTTGGGAGGCAATAGGCCACCATGCCTGGTCAGCACCAATTCAAGCCATGCCAGGAATCTGCCTAC CTGCCAGGTTCAGTTCTTTTAAGGTGCCTCTTCAGGGACACAGTGTGTCTCTCTGATTGGGCTTCTAAATCAAAAGCCTGATGTTCGTGT CCCTCTCATAGGGGGAGCTTTGGACACAGGACCAGTTTGGAAAAGGGTCAGGTAAGGGTTTCCACTCTGCACATTGTAGAGGGAACACTC TGTAGGCCCATGGGTCCCTTACTAGAGAGGTTGAGTGAATTTGCCTTCAGTTAACATGGGACCTTCTGTTTAGCTTCCTCTTGCTTCCCA AAGATTTTAAGCATTTTGTAAATGTATAAACTCACCTCTGGTAACAGTGGCCCAGACGCTGCTTTGTGCTAAAAGCATGGGAAATGTAAA GGCAGTCTTTCTCTGGGAAATGGATGCTATTCTATTCTGCTGCCCCTACCTGTTCCTGAGGCCTCATTTAGAAAGAAAATCCCCTCAGAA GGCTGTCTGGCACCCAGTGTCCTAGCCAGGCCAAGTATATGAGAAAGGTAAGTCCATTTTCCCCTTCAGGTCCTCAGTGGATTACTTAAC CACTGCTGTCCCTCGGTCCCTTTTTCCTAAACGGGTTTAGTTCTGTCTTTTTTCTCCTTTTTTCTAAATGCTGGTAAATATTTACATTCA GCCAGGGAAGAGGAGGCCAGAGGTCGGGCCAGCTGCCCCATTCTTTTAACGTTGTAGGGCCTGCCCATGGAGCGGACCCTCCTCTTTGGG CCTCGTGAGCTTTTTTGCTTATCATGTTCCATTTCGTGCCGCTTTCCCCCTTCAAGATGCCATTTGGAGGGTAGGGGATCTGCTTCCCAC TGTGACTGGGCTATGGGATTCTGACTACCTTGCTTACAGATTCATGGTTTGATAAATTTGTTGTATTCAAAAACTTGAAATGCAGGACGC CATTAAGTGTCTGTTTATATTTTTGGAATATTTGTATTACTTACAATTAATTAATAAAAGTGGGTTTAAAAAACCTTTCCAGGAA >65354_65354_3_PIK3C2G-CTDSP2_PIK3C2G_chr12_18435693_ENST00000535651_CTDSP2_chr12_58218102_ENST00000398073_length(amino acids)=360AA_BP=226 MAYSWQTDPNPNESHEKQYEHQEFLFVNQPHSSSQVSLGFDQIVDEISGKIPHYESEIDENTFFVPTAPKWDSTGHSLNEAHQISLNEFT SKSRELSWHQVSKAPAIGFSPSVLPKPQNTNKECSWGSPIGKHHGADDSRFSILAPSFTSLDKINLEKELENENHNYHIGFESSIPPTNS SFSSDFMPKEENKRSGHVNIVEPSLMLLKGSLQPGMWESTWQKNIEVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCG VFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPIFEELSGAEDVYTSLGQLRAP -------------------------------------------------------------- >65354_65354_4_PIK3C2G-CTDSP2_PIK3C2G_chr12_18435693_ENST00000538779_CTDSP2_chr12_58218102_ENST00000398073_length(transcript)=4796nt_BP=716nt GGAGCAGAGTCAACCCTCTCAGTTACATAAAATAAAAAATGGCATATTCTTGGCAAACGGATCCAAATCCTAATGAATCACACGAAAAGC AGTATGAACACCAAGAATTTCTCTTTGTAAATCAACCCCATTCTTCTAGCCAAGTCAGTCTGGGTTTTGATCAGATAGTAGATGAGATCA GTGGCAAAATTCCACACTACGAGAGTGAAATTGATGAAAACACCTTTTTTGTGCCCACTGCACCAAAATGGGACTCAACAGGGCATTCAT TAAATGAAGCACACCAAATATCCTTGAATGAATTCACTTCTAAAAGCCGTGAACTCTCCTGGCATCAAGTTAGCAAAGCACCAGCAATTG GTTTTAGTCCTTCTGTGTTACCAAAACCTCAAAATACGAATAAAGAATGCTCCTGGGGAAGCCCCATAGGAAAACATCATGGTGCTGATG ATTCCAGATTCAGTATTTTAGCTCCATCATTCACAAGTTTGGATAAAATTAATCTAGAGAAAGAATTAGAAAATGAAAATCATAACTACC ATATAGGATTTGAAAGTAGCATTCCTCCAACAAATTCATCCTTCTCAAGTGACTTCATGCCGAAAGAAGAGAATAAAAGGAGTGGACATG TGAACATTGTGGAACCATCTTTGATGCTTTTGAAAGGCTCTCTTCAACCCGGAATGTGGGAAAGTACATGGCAGAAGAATATAGAGGTGT ATGTGCTCAAGAGGCCTTATGTGGATGAGTTCCTGAGACGCATGGGGGAACTCTTTGAATGTGTTCTCTTCACTGCCAGCCTGGCCAAGT ATGCCGACCCTGTGACAGACCTGCTGGACCGGTGTGGGGTGTTCCGGGCCCGCCTATTCCGTGAGTCTTGCGTGTTCCACCAGGGCTGCT ACGTCAAGGACCTCAGCCGCCTGGGGAGGGACCTGAGAAAGACCCTCATCCTGGACAACTCGCCTGCTTCTTACATATTCCACCCCGAGA ATGCAGTGCCTGTGCAGTCCTGGTTTGATGACATGGCAGACACTGAGTTGCTGAACCTGATCCCAATCTTTGAGGAGCTGAGCGGAGCAG AGGACGTCTACACCAGCCTTGGGCAGCTGCGGGCCCCTTAGCCTGCCCTGCTTCCAAGCGACGGCCATCCCAGTAGGGGACTTTCCCACA CTGTGCCTTTACGATCAGCGTGACAGAGTAGAAGCTGGAGTGCCTCACCACACGGCCCGGAAACAGCGGGAAGTAACTGGAAAGAGCTTT AGGACAGCTTAGATGCCGAGTGGGCGAATGCCAGACCAATGATACCCAGAGCTACCTGCCGCCAACTTGTTGAGATGTGTGTTTGACTGT GAGAGAGTGTGTGTTTGTGTGTGTGTTTTGCCATGAACTGTGGCCCCAGTGTATAGTGTTTCAGTGGGGGAGAAGCTGAAAGACCAAGAC TCTTCCCAAGTTAGCTTGTCTCCTCTCCTGTCACCCTAAGAGCCACTGAGTTGTGTAGGGATGAAGACTATTGAAGACTCCATTGCCAAA CCATGGCCTTTCCTCAGTGTTGTAAGGCCTATGCCAAGGATAAAGGAAGGGTATGCCTTTGGGTACTCCAGGCACACACCTTTCTGAAAT CCTTCTCCAGCCAGCTGCTGCAGACAAAAGATCACATTTCTGGGAAGATGAGAACTTGTTTCCAGACCAGCATCCAGTGGCCATCAGGTC TTGTGGCCCAAAGGCTATGCTTGCCTCCGGCTGAGTGCCTGGGATAGGCCTTTTCTATGTCTCCCCAAGGCTGGGGTGCTGAGCCTGCCT TCCTCACCACCTAGCCATAGTCTCAAACCTGTGGGGAAGGAGGTTTTCTCCCTGCCCGGGAAGAGGACAGATAACTGATTTCCGTTCTTT TGACTGTGTTTTAAAATTCTCTTTCTAAACACAGAGTGTTGGGCCTGGTTTGTTTCTGACAAAGTTACAGTCCTGGGCCTGTAATGAATG TCGGCGGCGCTGGGGTTGCAGGGAAAAGACAAATCCTCAAAGCGTGGACGTGTGTCCCCATGGCTTGTGGATCAGCTAAGCTCGGGATCA TTTCCATAAGTCTGCTTTTCAGGGATTCTCTGCTGGTGCTGGTGCAAGGACTTCTGTTCCAAAGGCTGGGAAAAACTAAGCTGTCCCAGC CCCTCCCATTTCTTGGGCAGGGCTCTTTTCCTGTTGTGTCTTCCCCCAGGGCCTGTCCTGTACCGAGCTCTGTCTGTTCCAGCCTTCATC CTTCCTGGCTGTTGCTTTTCCTCTTAAGGGCCTCAGAACTCTTGCTCTTCCTGGGCTGAGGGGGAATGAGTGTTCTTGCCATTTGCCAGC CTAATGCGCATGCTTTCTGCCTCTGGTAACAGGAGTGAGTGAGCCCCTCAGACCTGCACTCTGGGTGTCTCCTGCTTTCAAAGGTTCTTA ATAGTGAATGCTTTAAAATTAAAGTCATCACGAAATGGAAGTTTTCCCAGGGTGGAAAATAAGAGGAAGTGCTGCTGTAATTGGGAGCAC AAGGGGCCTCCCAAAAAGGAGCCCCACCTCAGCATCACTGCCTTAATCGTGGCCTCCCTGGGGTGGGTGGGGTTCTCTCCTCCCTCCCTC CCTCCTCCTGGGGTGGGAGGGCGCTCCTGTTCCCATCTCTGTGTTCCCTGGAGGCAGGTATCACAAAGCATTTGTGAATTGCTTTAGGTG CAGGGACACCACCCACTCAGGACTCTTCCCCATCATCCCTTCCATTGCCACACCCTAGATCCAGCCTCAGGAACTAACAAGTTTTGAGAA AAGCAGGTAGTAGAGCAGCAGCTTCGTGCTCTCAGCGGTGGCTGGCTGGCATTTTTCTCTAGCGTTGTGGTGCCACCTTCCCTTCTTGTC CCAAGGTTATAAGGCCTTGTCTTTCTCTTTGGAATCATAAAGTGGAACAGAGTCCCCAGAACTCATGTGGCCATTTCCGCCAGCATCACT CCCCGGTGCCTATGGGGTCCCGGTGTACCTAAAGGGAGAAGGACCCCATGTGCTAGCCAGAAATATACTGTCTCTTGAAGGAAAGCAGGA GCTCAGACTCTTAGAGCCAGCTGTGGCTTCGGACCCAAGGCCTGACCTAGGCTGCTATCCTAATATTGCAGGAGGGGCCTCTCTTCCAAG CCCCACCCTAAGGGTTAGCCCTTGGCCAAATCTTTTGCCGTCTAGGCCCAGCCAGGCTTTTCTGACTAAATAAGCAATAAGAGGCTCTAA GCTGACTGAGTTGCAAGGACCCTTTCCGCCCTCCCTTGGATCTCCATGTTTTTCCAGATGGCGGAAGAGCATGTGCCACCCCCTTTCCTA ACAGACTTGTCCAAGTGCTTGGCGTGGGACCCATGACCAAAGCCCAGGATGGCTTGGTGGGAGTGTCCCTGCTGCATCTGCATGAAGCCC CTGCTTTTTAGGCCTCACTCCCATCAGAACCCTGCCTGCCCACCTGCAACTCCCCCCCAACAATGCCATTCCCACTTGCCCCAGAGAAGC TACTCGGCCAAACCTAGCCAGGGTCTGTTCTTGTGGACCAGAGCCAGCCTAGTCATTATTTGCTGTCGGGTTTCCAGTTTCACCGTGTGT TAGGGTGAGGGATGATTGTAAAATTTGCTCCTCAAAGGAATCAGGCCAGACTCAATTTTGGAGGGCAAGACAGGGAGGAGGCCGCTTCAT CCCAGACTCTCTTCTAGGGCTTCCCACCATCAGCCCCTCCCACTTGAGACTGGTCTTTGGGAGGCAATAGGCCACCATGCCTGGTCAGCA CCAATTCAAGCCATGCCAGGAATCTGCCTACCTGCCAGGTTCAGTTCTTTTAAGGTGCCTCTTCAGGGACACAGTGTGTCTCTCTGATTG GGCTTCTAAATCAAAAGCCTGATGTTCGTGTCCCTCTCATAGGGGGAGCTTTGGACACAGGACCAGTTTGGAAAAGGGTCAGGTAAGGGT TTCCACTCTGCACATTGTAGAGGGAACACTCTGTAGGCCCATGGGTCCCTTACTAGAGAGGTTGAGTGAATTTGCCTTCAGTTAACATGG GACCTTCTGTTTAGCTTCCTCTTGCTTCCCAAAGATTTTAAGCATTTTGTAAATGTATAAACTCACCTCTGGTAACAGTGGCCCAGACGC TGCTTTGTGCTAAAAGCATGGGAAATGTAAAGGCAGTCTTTCTCTGGGAAATGGATGCTATTCTATTCTGCTGCCCCTACCTGTTCCTGA GGCCTCATTTAGAAAGAAAATCCCCTCAGAAGGCTGTCTGGCACCCAGTGTCCTAGCCAGGCCAAGTATATGAGAAAGGTAAGTCCATTT TCCCCTTCAGGTCCTCAGTGGATTACTTAACCACTGCTGTCCCTCGGTCCCTTTTTCCTAAACGGGTTTAGTTCTGTCTTTTTTCTCCTT TTTTCTAAATGCTGGTAAATATTTACATTCAGCCAGGGAAGAGGAGGCCAGAGGTCGGGCCAGCTGCCCCATTCTTTTAACGTTGTAGGG CCTGCCCATGGAGCGGACCCTCCTCTTTGGGCCTCGTGAGCTTTTTTGCTTATCATGTTCCATTTCGTGCCGCTTTCCCCCTTCAAGATG CCATTTGGAGGGTAGGGGATCTGCTTCCCACTGTGACTGGGCTATGGGATTCTGACTACCTTGCTTACAGATTCATGGTTTGATAAATTT GTTGTATTCAAAAACTTGAAATGCAGGACGCCATTAAGTGTCTGTTTATATTTTTGGAATATTTGTATTACTTACAATTAATTAATAAAA GTGGGTTTAAAAAACCTTTCCAGGAA >65354_65354_4_PIK3C2G-CTDSP2_PIK3C2G_chr12_18435693_ENST00000538779_CTDSP2_chr12_58218102_ENST00000398073_length(amino acids)=360AA_BP=226 MAYSWQTDPNPNESHEKQYEHQEFLFVNQPHSSSQVSLGFDQIVDEISGKIPHYESEIDENTFFVPTAPKWDSTGHSLNEAHQISLNEFT SKSRELSWHQVSKAPAIGFSPSVLPKPQNTNKECSWGSPIGKHHGADDSRFSILAPSFTSLDKINLEKELENENHNYHIGFESSIPPTNS SFSSDFMPKEENKRSGHVNIVEPSLMLLKGSLQPGMWESTWQKNIEVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCG VFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPIFEELSGAEDVYTSLGQLRAP -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for PIK3C2G-CTDSP2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for PIK3C2G-CTDSP2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for PIK3C2G-CTDSP2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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